Incidental Mutation 'R8878:Zfp236'
| ID |
676736 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp236
|
| Ensembl Gene |
ENSMUSG00000041258 |
| Gene Name |
zinc finger protein 236 |
| Synonyms |
LOC240456 |
| MMRRC Submission |
068746-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8878 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
82611718-82711008 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 82617122 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Methionine
at position 1791
(T1791M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138557
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000171071]
[ENSMUST00000182122]
[ENSMUST00000183048]
|
| AlphaFold |
S4R299 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171071
AA Change: T1743M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130004
Gene: ENSMUSG00000041258
AA Change: T1743M
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
low complexity region
|
290 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
403 |
426 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
436 |
458 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
464 |
486 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
492 |
514 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
520 |
542 |
1.18e-2 |
SMART |
|
low complexity region
|
592 |
605 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
611 |
633 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
639 |
661 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
667 |
689 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
695 |
717 |
7.37e-4 |
SMART |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
922 |
944 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
950 |
972 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
978 |
1000 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1006 |
1028 |
2.75e-3 |
SMART |
|
low complexity region
|
1030 |
1039 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1122 |
1144 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1150 |
1172 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1178 |
1200 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1206 |
1228 |
5.42e-2 |
SMART |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1462 |
1477 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1612 |
1635 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1641 |
1663 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1733 |
1756 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182122
AA Change: T1791M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000138557
Gene: ENSMUSG00000041258
AA Change: T1791M
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
474 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
484 |
506 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
512 |
534 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
540 |
562 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
568 |
590 |
1.18e-2 |
SMART |
|
low complexity region
|
640 |
653 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
659 |
681 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
687 |
709 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
715 |
737 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
743 |
765 |
7.37e-4 |
SMART |
|
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
970 |
992 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
998 |
1020 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1026 |
1048 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1054 |
1076 |
2.75e-3 |
SMART |
|
low complexity region
|
1078 |
1087 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1198 |
1220 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1226 |
1248 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1254 |
1276 |
5.42e-2 |
SMART |
|
low complexity region
|
1291 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1525 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1660 |
1683 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1689 |
1711 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1725 |
1747 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1753 |
1775 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1781 |
1804 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183048
|
| SMART Domains |
Protein: ENSMUSP00000138179
Gene: ENSMUSG00000041258
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
467 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183324
|
| Meta Mutation Damage Score |
0.3321 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (73/74) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss2 |
C |
A |
2: 155,398,324 (GRCm39) |
H348Q |
probably benign |
Het |
| Ago1 |
T |
A |
4: 126,357,516 (GRCm39) |
Y53F |
probably benign |
Het |
| Arrdc5 |
A |
G |
17: 56,601,342 (GRCm39) |
L261P |
probably benign |
Het |
| Asb2 |
C |
A |
12: 103,290,138 (GRCm39) |
W551L |
possibly damaging |
Het |
| Atl2 |
T |
C |
17: 80,160,232 (GRCm39) |
I452V |
probably benign |
Het |
| Atxn7l3 |
T |
C |
11: 102,183,545 (GRCm39) |
S203G |
probably benign |
Het |
| Bche |
A |
G |
3: 73,608,506 (GRCm39) |
F307L |
probably benign |
Het |
| C6 |
T |
C |
15: 4,826,454 (GRCm39) |
V679A |
probably benign |
Het |
| Cd163 |
A |
T |
6: 124,297,469 (GRCm39) |
N872Y |
probably damaging |
Het |
| Cdkal1 |
C |
A |
13: 29,658,607 (GRCm39) |
V380F |
probably damaging |
Het |
| Ceacam11 |
A |
T |
7: 17,709,536 (GRCm39) |
I245L |
probably benign |
Het |
| Ceacam16 |
G |
T |
7: 19,592,656 (GRCm39) |
T84K |
possibly damaging |
Het |
| Ceacam2 |
T |
A |
7: 25,227,351 (GRCm39) |
Q172L |
probably benign |
Het |
| Chga |
T |
G |
12: 102,527,720 (GRCm39) |
S125A |
possibly damaging |
Het |
| Col9a1 |
T |
C |
1: 24,236,048 (GRCm39) |
|
probably null |
Het |
| Crybg3 |
C |
A |
16: 59,380,547 (GRCm39) |
A236S |
probably benign |
Het |
| Csmd1 |
A |
G |
8: 15,960,528 (GRCm39) |
Y3296H |
probably damaging |
Het |
| Cyp2j8 |
C |
A |
4: 96,358,807 (GRCm39) |
V371L |
possibly damaging |
Het |
| Des |
C |
A |
1: 75,337,137 (GRCm39) |
L26M |
unknown |
Het |
| Edc3 |
A |
G |
9: 57,623,484 (GRCm39) |
S140G |
possibly damaging |
Het |
| Fam161a |
C |
T |
11: 22,970,092 (GRCm39) |
T90I |
probably benign |
Het |
| Fancm |
T |
C |
12: 65,173,522 (GRCm39) |
Y1945H |
probably damaging |
Het |
| Fbn2 |
C |
T |
18: 58,257,318 (GRCm39) |
V350I |
probably benign |
Het |
| Git2 |
A |
G |
5: 114,899,649 (GRCm39) |
C235R |
possibly damaging |
Het |
| Gk2 |
T |
C |
5: 97,604,341 (GRCm39) |
K166E |
probably benign |
Het |
| Gm12258 |
G |
A |
11: 58,750,112 (GRCm39) |
R429H |
unknown |
Het |
| Gm7247 |
T |
G |
14: 51,666,210 (GRCm39) |
|
probably benign |
Het |
| Gmppa |
A |
G |
1: 75,414,932 (GRCm39) |
Y59C |
probably damaging |
Het |
| Has1 |
G |
T |
17: 18,070,321 (GRCm39) |
A200E |
possibly damaging |
Het |
| Hbs1l |
T |
C |
10: 21,234,711 (GRCm39) |
I588T |
possibly damaging |
Het |
| Helz2 |
A |
G |
2: 180,874,560 (GRCm39) |
V1978A |
possibly damaging |
Het |
| Hoxb9 |
T |
C |
11: 96,165,557 (GRCm39) |
Y209H |
probably damaging |
Het |
| Hps5 |
T |
C |
7: 46,421,345 (GRCm39) |
D706G |
probably benign |
Het |
| Hydin |
T |
C |
8: 111,035,720 (GRCm39) |
V137A |
probably benign |
Het |
| Ifngr2 |
T |
C |
16: 91,359,847 (GRCm39) |
I318T |
probably benign |
Het |
| Iqgap3 |
C |
T |
3: 88,020,532 (GRCm39) |
T1290I |
probably damaging |
Het |
| Jrk |
A |
T |
15: 74,578,988 (GRCm39) |
V99E |
probably benign |
Het |
| Kalrn |
G |
A |
16: 34,018,830 (GRCm39) |
P1311S |
probably benign |
Het |
| Kalrn |
G |
A |
16: 34,025,696 (GRCm39) |
T931M |
probably damaging |
Het |
| Kirrel3 |
A |
G |
9: 34,850,561 (GRCm39) |
|
probably benign |
Het |
| Klk1b9 |
T |
C |
7: 43,443,782 (GRCm39) |
F99L |
possibly damaging |
Het |
| Lamb3 |
T |
C |
1: 193,013,124 (GRCm39) |
C450R |
probably damaging |
Het |
| Lyst |
T |
A |
13: 13,815,661 (GRCm39) |
S1182T |
probably benign |
Het |
| Map1a |
T |
C |
2: 121,138,125 (GRCm39) |
V2933A |
probably damaging |
Het |
| Map2k5 |
A |
T |
9: 63,250,667 (GRCm39) |
|
probably null |
Het |
| Mcm6 |
A |
G |
1: 128,283,248 (GRCm39) |
|
probably null |
Het |
| Mmp17 |
G |
A |
5: 129,683,378 (GRCm39) |
V505M |
probably damaging |
Het |
| Mpped2 |
A |
G |
2: 106,575,065 (GRCm39) |
D50G |
probably damaging |
Het |
| Mtf1 |
T |
A |
4: 124,715,023 (GRCm39) |
L216* |
probably null |
Het |
| Niban2 |
A |
T |
2: 32,811,105 (GRCm39) |
M372L |
probably benign |
Het |
| Obscn |
T |
C |
11: 58,890,638 (GRCm39) |
E7298G |
unknown |
Het |
| Or52ab7 |
A |
T |
7: 102,978,212 (GRCm39) |
H173L |
possibly damaging |
Het |
| Or56a3 |
T |
C |
7: 104,735,763 (GRCm39) |
L280P |
probably damaging |
Het |
| Or6c205 |
T |
C |
10: 129,086,883 (GRCm39) |
L160P |
probably benign |
Het |
| Or7d9 |
A |
G |
9: 20,197,358 (GRCm39) |
D129G |
probably damaging |
Het |
| Otulinl |
T |
A |
15: 27,664,884 (GRCm39) |
H24L |
probably benign |
Het |
| Pax2 |
G |
A |
19: 44,777,215 (GRCm39) |
|
probably null |
Het |
| Pcnt |
T |
A |
10: 76,244,675 (GRCm39) |
E1135V |
probably damaging |
Het |
| Pgap3 |
A |
T |
11: 98,281,924 (GRCm39) |
V129D |
probably benign |
Het |
| Polq |
A |
G |
16: 36,860,869 (GRCm39) |
N497S |
probably benign |
Het |
| Ppfia4 |
T |
C |
1: 134,227,122 (GRCm39) |
T1138A |
|
Het |
| Prickle4 |
A |
G |
17: 48,001,587 (GRCm39) |
L32P |
|
Het |
| Prl2c2 |
C |
T |
13: 13,171,896 (GRCm39) |
G158R |
probably damaging |
Het |
| Psd3 |
A |
G |
8: 68,210,750 (GRCm39) |
I752T |
probably benign |
Het |
| Sag |
A |
T |
1: 87,756,158 (GRCm39) |
Y255F |
probably benign |
Het |
| Scn7a |
A |
T |
2: 66,506,199 (GRCm39) |
D1563E |
probably damaging |
Het |
| Secisbp2 |
A |
G |
13: 51,837,404 (GRCm39) |
N855S |
probably benign |
Het |
| Setd2 |
T |
C |
9: 110,421,467 (GRCm39) |
V2011A |
probably benign |
Het |
| Slc30a6 |
T |
C |
17: 74,730,112 (GRCm39) |
V334A |
probably damaging |
Het |
| Spen |
A |
G |
4: 141,204,520 (GRCm39) |
V1369A |
unknown |
Het |
| Stac2 |
T |
C |
11: 97,932,373 (GRCm39) |
T207A |
probably benign |
Het |
| Syne2 |
T |
C |
12: 75,952,067 (GRCm39) |
V445A |
probably benign |
Het |
| Tas2r131 |
C |
A |
6: 132,934,467 (GRCm39) |
W114L |
probably damaging |
Het |
| Tgfbrap1 |
G |
A |
1: 43,088,959 (GRCm39) |
R815* |
probably null |
Het |
| Trpv2 |
A |
T |
11: 62,481,112 (GRCm39) |
I404L |
probably benign |
Het |
|
| Other mutations in Zfp236 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Zfp236
|
APN |
18 |
82,686,815 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01760:Zfp236
|
APN |
18 |
82,639,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01923:Zfp236
|
APN |
18 |
82,700,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01934:Zfp236
|
APN |
18 |
82,651,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01949:Zfp236
|
APN |
18 |
82,642,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02063:Zfp236
|
APN |
18 |
82,676,276 (GRCm39) |
missense |
probably benign |
|
|
IGL02496:Zfp236
|
APN |
18 |
82,648,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02513:Zfp236
|
APN |
18 |
82,648,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Zfp236
|
APN |
18 |
82,676,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL02880:Zfp236
|
APN |
18 |
82,642,584 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03156:Zfp236
|
APN |
18 |
82,698,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Zfp236
|
APN |
18 |
82,648,733 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0047:Zfp236
|
UTSW |
18 |
82,698,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Zfp236
|
UTSW |
18 |
82,657,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0194:Zfp236
|
UTSW |
18 |
82,675,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Zfp236
|
UTSW |
18 |
82,658,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0302:Zfp236
|
UTSW |
18 |
82,676,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0730:Zfp236
|
UTSW |
18 |
82,658,369 (GRCm39) |
splice site |
probably benign |
|
|
R0755:Zfp236
|
UTSW |
18 |
82,638,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1202:Zfp236
|
UTSW |
18 |
82,646,291 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1449:Zfp236
|
UTSW |
18 |
82,664,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Zfp236
|
UTSW |
18 |
82,692,549 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1785:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1786:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2042:Zfp236
|
UTSW |
18 |
82,651,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2133:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2247:Zfp236
|
UTSW |
18 |
82,622,423 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2484:Zfp236
|
UTSW |
18 |
82,686,762 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3715:Zfp236
|
UTSW |
18 |
82,651,095 (GRCm39) |
splice site |
probably benign |
|
|
R4003:Zfp236
|
UTSW |
18 |
82,698,870 (GRCm39) |
nonsense |
probably null |
|
|
R4031:Zfp236
|
UTSW |
18 |
82,642,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4482:Zfp236
|
UTSW |
18 |
82,662,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4492:Zfp236
|
UTSW |
18 |
82,648,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4502:Zfp236
|
UTSW |
18 |
82,655,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4561:Zfp236
|
UTSW |
18 |
82,638,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp236
|
UTSW |
18 |
82,615,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Zfp236
|
UTSW |
18 |
82,627,543 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5064:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5084:Zfp236
|
UTSW |
18 |
82,627,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Zfp236
|
UTSW |
18 |
82,637,006 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5191:Zfp236
|
UTSW |
18 |
82,639,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5264:Zfp236
|
UTSW |
18 |
82,676,198 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5264:Zfp236
|
UTSW |
18 |
82,648,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5339:Zfp236
|
UTSW |
18 |
82,642,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Zfp236
|
UTSW |
18 |
82,615,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5445:Zfp236
|
UTSW |
18 |
82,700,281 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5513:Zfp236
|
UTSW |
18 |
82,676,147 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5527:Zfp236
|
UTSW |
18 |
82,676,159 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5628:Zfp236
|
UTSW |
18 |
82,675,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5758:Zfp236
|
UTSW |
18 |
82,689,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Zfp236
|
UTSW |
18 |
82,658,276 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6137:Zfp236
|
UTSW |
18 |
82,689,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6193:Zfp236
|
UTSW |
18 |
82,622,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6198:Zfp236
|
UTSW |
18 |
82,675,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Zfp236
|
UTSW |
18 |
82,675,229 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6705:Zfp236
|
UTSW |
18 |
82,651,862 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6948:Zfp236
|
UTSW |
18 |
82,662,187 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6989:Zfp236
|
UTSW |
18 |
82,646,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7113:Zfp236
|
UTSW |
18 |
82,638,462 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7261:Zfp236
|
UTSW |
18 |
82,627,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7363:Zfp236
|
UTSW |
18 |
82,639,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Zfp236
|
UTSW |
18 |
82,651,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7564:Zfp236
|
UTSW |
18 |
82,662,366 (GRCm39) |
nonsense |
probably null |
|
|
R7731:Zfp236
|
UTSW |
18 |
82,698,798 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7857:Zfp236
|
UTSW |
18 |
82,686,726 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Zfp236
|
UTSW |
18 |
82,692,481 (GRCm39) |
nonsense |
probably null |
|
|
R7904:Zfp236
|
UTSW |
18 |
82,627,507 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7948:Zfp236
|
UTSW |
18 |
82,642,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp236
|
UTSW |
18 |
82,657,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Zfp236
|
UTSW |
18 |
82,648,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Zfp236
|
UTSW |
18 |
82,658,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Zfp236
|
UTSW |
18 |
82,664,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Zfp236
|
UTSW |
18 |
82,664,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Zfp236
|
UTSW |
18 |
82,637,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9076:Zfp236
|
UTSW |
18 |
82,638,469 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9243:Zfp236
|
UTSW |
18 |
82,662,050 (GRCm39) |
intron |
probably benign |
|
|
R9594:Zfp236
|
UTSW |
18 |
82,664,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9642:Zfp236
|
UTSW |
18 |
82,622,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Zfp236
|
UTSW |
18 |
82,664,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Zfp236
|
UTSW |
18 |
82,637,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCACAGGCTTCAACTCTTGTC -3'
(R):5'- TCAACACTGAGCTGACTGGAATG -3'
Sequencing Primer
(F):5'- TCTATATGTGCAGTCCTTACAGG -3'
(R):5'- AGTGACATTGTGCTCTGCTAAAG -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation