Incidental Mutation 'IGL00340:Lrrc39'
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ID6771
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lrrc39
Ensembl Gene ENSMUSG00000027961
Gene Nameleucine rich repeat containing 39
Synonyms2010005E21Rik, 9430028I06Rik
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.336) question?
Stock #IGL00340
Quality Score
Status
Chromosome3
Chromosomal Location116562973-116583134 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 116570981 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000029573 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000029573]
Predicted Effect probably benign
Transcript: ENSMUST00000029573
SMART Domains Protein: ENSMUSP00000029573
Gene: ENSMUSG00000027961

DomainStartEndE-ValueType
LRR 105 127 1.15e1 SMART
LRR_TYP 128 151 7.26e-3 SMART
LRR 175 197 6.58e0 SMART
LRR 198 220 1e1 SMART
LRR 221 243 7.16e0 SMART
LRR 244 267 6.58e0 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000200361
Predicted Effect noncoding transcript
Transcript: ENSMUST00000203327
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 62 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930430A15Rik G T 2: 111,220,762 L230I probably damaging Het
Adamts3 G A 5: 89,701,666 H632Y probably damaging Het
Adgre5 T A 8: 83,728,401 M221L probably benign Het
Apba2 A T 7: 64,736,941 I439F possibly damaging Het
Arid1b C A 17: 5,321,284 N632K probably damaging Het
Bcas3 A T 11: 85,365,591 I60L probably damaging Het
Brd9 T C 13: 73,938,547 S56P probably damaging Het
Ccdc57 T A 11: 120,860,469 D925V possibly damaging Het
Ccna1 A G 3: 55,050,655 V143A probably damaging Het
Cdhr3 T C 12: 33,052,209 T410A probably benign Het
Ddx60 G T 8: 61,958,646 D511Y probably damaging Het
Drc7 C A 8: 95,056,001 probably benign Het
Dysf A G 6: 84,141,951 E1290G probably benign Het
Fam168b T C 1: 34,836,802 M1V probably null Het
Farsa A G 8: 84,864,257 K208R probably damaging Het
Fnip2 A G 3: 79,518,061 probably benign Het
Gm17535 A T 9: 3,035,111 H170L probably benign Het
Gm4553 T C 7: 142,165,227 S155G unknown Het
Gm5852 T C 3: 93,727,194 noncoding transcript Het
Gnb2 T C 5: 137,530,706 probably benign Het
Gpr158 A G 2: 21,368,683 N143S probably damaging Het
Hcn1 C A 13: 117,602,977 Q92K unknown Het
Helb T C 10: 120,098,245 I678V possibly damaging Het
Hnrnpl C A 7: 28,813,373 A118D probably damaging Het
Klhl14 G A 18: 21,651,864 P169S probably benign Het
Kndc1 T C 7: 139,901,988 probably benign Het
Lmod2 A G 6: 24,598,052 E57G probably damaging Het
Lrch4 T C 5: 137,637,747 I300T possibly damaging Het
Lrp6 A G 6: 134,456,090 V1426A probably benign Het
Mamstr G A 7: 45,644,285 V262I probably benign Het
Mob1b A T 5: 88,756,155 T217S probably benign Het
Mocs3 G A 2: 168,231,491 R286H possibly damaging Het
Mpo A T 11: 87,802,617 Q27L probably benign Het
Ncdn A T 4: 126,747,188 D506E probably benign Het
Noxa1 A G 2: 25,094,902 I8T probably benign Het
Olfr46 T A 7: 140,610,753 S196T probably damaging Het
Olfr514 C T 7: 108,825,073 V309I probably benign Het
Olfr878 A G 9: 37,919,050 Y131C probably damaging Het
Oma1 G T 4: 103,319,368 A110S probably benign Het
Pde4a A C 9: 21,211,061 K694T probably benign Het
Phc1 A G 6: 122,322,999 probably benign Het
Pias1 A G 9: 62,923,296 V187A probably damaging Het
Pifo A G 3: 106,014,508 V33A probably benign Het
Pigf C A 17: 87,020,448 L130F probably null Het
Pkd1 G T 17: 24,580,095 V2763L probably damaging Het
Ppp1r8 T C 4: 132,834,681 Y76C probably damaging Het
Ppp6r3 C A 19: 3,518,324 G158V probably damaging Het
Ptpn13 A G 5: 103,551,058 I1136V probably damaging Het
Ptprq T C 10: 107,576,929 I1770V probably damaging Het
Rhpn2 A T 7: 35,370,760 I148F probably damaging Het
Stard3 T C 11: 98,377,459 Y239H probably damaging Het
Stau1 T C 2: 166,950,809 Y412C probably benign Het
Sucnr1 A G 3: 60,086,632 I194V probably benign Het
Tanc1 A G 2: 59,790,841 T335A possibly damaging Het
Tmem126a T C 7: 90,452,755 T79A probably benign Het
Trav9-2 A T 14: 53,591,383 Y70F probably benign Het
Tspear A G 10: 77,873,236 E432G probably benign Het
Ube2o T C 11: 116,544,754 R403G probably benign Het
Unc80 C A 1: 66,606,459 S1431R possibly damaging Het
Usp24 G A 4: 106,401,139 C1578Y probably damaging Het
Vsig10 A T 5: 117,351,587 M473L probably benign Het
Xpot T A 10: 121,605,644 M559L probably benign Het
Other mutations in Lrrc39
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01017:Lrrc39 APN 3 116570851 missense probably benign 0.01
IGL01717:Lrrc39 APN 3 116579497 unclassified probably benign
IGL01728:Lrrc39 APN 3 116579500 unclassified probably benign
IGL02208:Lrrc39 APN 3 116578274 missense probably damaging 1.00
IGL02801:Lrrc39 APN 3 116578346 missense possibly damaging 0.89
R0279:Lrrc39 UTSW 3 116578303 missense probably benign 0.19
R1351:Lrrc39 UTSW 3 116565820 missense possibly damaging 0.51
R1436:Lrrc39 UTSW 3 116579644 splice site probably null
R1641:Lrrc39 UTSW 3 116570913 missense probably damaging 0.99
R1716:Lrrc39 UTSW 3 116579567 missense probably benign 0.00
R2199:Lrrc39 UTSW 3 116570961 missense probably damaging 0.97
R2410:Lrrc39 UTSW 3 116581250 missense probably benign 0.02
R4696:Lrrc39 UTSW 3 116570120 missense probably damaging 1.00
R4816:Lrrc39 UTSW 3 116568866 critical splice donor site probably null
R5076:Lrrc39 UTSW 3 116579540 missense probably benign 0.37
R6152:Lrrc39 UTSW 3 116570975 critical splice donor site probably null
R7124:Lrrc39 UTSW 3 116565913 missense probably benign
X0028:Lrrc39 UTSW 3 116565871 missense probably damaging 1.00
Posted On2012-04-20