Mutagenetix > Incidental Mutation

Incidental Mutation 'R8885:Dnah3'

677242

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

Dnahc3

MMRRC Submission

068751-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R8885 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

119521894-119694503 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 119561375 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 328 (I328F)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000046993
AA Change: I2715F

PolyPhen 2 Score 0.458 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: I2715F

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000209154
AA Change: I2704F

PolyPhen 2 Score 0.307 (Sensitivity: 0.90; Specificity: 0.89)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

100% (104/104)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 106 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2210408I21Rik	A	T	13: 77,471,525 (GRCm39)	S977C	possibly damaging	Het
Abca8a	T	A	11: 109,960,305 (GRCm39)	D646V	probably damaging	Het
Adss2	T	A	1: 177,597,526 (GRCm39)	Y378F	probably damaging	Het
Akap6	C	T	12: 53,188,319 (GRCm39)	A1911V	probably benign	Het
Alg2	T	C	4: 47,474,159 (GRCm39)	Y43C	probably benign	Het
Alk	A	C	17: 72,202,758 (GRCm39)	V1159G	probably damaging	Het
Alx3	A	T	3: 107,508,010 (GRCm39)	Q173L	probably damaging	Het
Aqp9	A	G	9: 71,069,593 (GRCm39)		probably benign	Het
Atf7ip	C	A	6: 136,564,141 (GRCm39)	L787I	probably benign	Het
Bbs9	A	T	9: 22,590,234 (GRCm39)	E657D	possibly damaging	Het
Bean1	G	A	8: 104,908,752 (GRCm39)		probably null	Het
Cactin	G	T	10: 81,157,082 (GRCm39)	R13L	unknown	Het
Ccdc178	T	C	18: 22,200,721 (GRCm39)	E412G	probably damaging	Het
Ccdc30	A	G	4: 119,181,759 (GRCm39)	I583T	probably damaging	Het
Ccl8	T	C	11: 82,006,933 (GRCm39)	Y49H	probably damaging	Het
Clptm1	T	A	7: 19,372,932 (GRCm39)	K199N	probably damaging	Het
Cnbp	G	A	6: 87,822,646 (GRCm39)	S39L	probably benign	Het
Cnih3	T	A	1: 181,237,437 (GRCm39)		probably benign	Het
Cnksr3	A	T	10: 7,090,201 (GRCm39)		probably benign	Het
Cntn1	A	G	15: 92,159,380 (GRCm39)	I512V	probably benign	Het
Col20a1	A	G	2: 180,640,296 (GRCm39)		probably benign	Het
Col28a1	A	T	6: 8,127,360 (GRCm39)		probably benign	Het
Col6a2	A	T	10: 76,450,741 (GRCm39)	Y63*	probably null	Het
Copa	T	G	1: 171,925,312 (GRCm39)	F190V	probably damaging	Het
Crisp4	A	C	1: 18,207,148 (GRCm39)		probably benign	Het
Cxcl2	C	T	5: 91,052,085 (GRCm39)	Q64*	probably null	Het
Cxcr5	T	C	9: 44,425,549 (GRCm39)	D36G	probably benign	Het
Cyp20a1	T	A	1: 60,411,765 (GRCm39)	V271E	possibly damaging	Het
D430041D05Rik	T	C	2: 104,071,538 (GRCm39)	Y570C	probably damaging	Het
Ddi1	T	G	9: 6,266,198 (GRCm39)	D57A	probably benign	Het
Ddx11	T	A	17: 66,450,460 (GRCm39)	S492T	probably benign	Het
Dhx34	C	T	7: 15,950,376 (GRCm39)	R264H	probably damaging	Het
Dnah5	C	T	15: 28,327,886 (GRCm39)	R2087C	probably damaging	Het
Dnah8	C	G	17: 30,927,286 (GRCm39)	S1314W	possibly damaging	Het
Dock2	T	C	11: 34,260,396 (GRCm39)	N982D	probably benign	Het
Dync1h1	A	G	12: 110,583,172 (GRCm39)	D423G	probably damaging	Het
Ect2l	A	C	10: 18,048,583 (GRCm39)	L213V	probably damaging	Het
Fam210a	T	C	18: 68,409,215 (GRCm39)	I32V	probably benign	Het
Fancg	A	G	4: 43,007,266 (GRCm39)		probably null	Het
Fastkd5	T	C	2: 130,457,111 (GRCm39)	E493G	probably benign	Het
Fbxo38	T	C	18: 62,659,272 (GRCm39)	M342V	probably damaging	Het
Flnc	A	C	6: 29,455,410 (GRCm39)	K2020Q	probably damaging	Het
Flt4	A	G	11: 49,527,160 (GRCm39)		probably benign	Het
Frmd4b	G	T	6: 97,389,480 (GRCm39)	P129T	probably benign	Het
Galnt13	C	A	2: 54,770,138 (GRCm39)	A310E	probably benign	Het
Gm4884	T	A	7: 40,694,108 (GRCm39)	Y692*	probably null	Het
Gm6309	T	A	5: 146,105,103 (GRCm39)	D270V	probably damaging	Het
Grip1	G	T	10: 119,290,192 (GRCm39)		probably benign	Het
Itpr3	G	A	17: 27,337,651 (GRCm39)		probably benign	Het
Kdf1	G	T	4: 133,255,505 (GRCm39)	C74F	probably damaging	Het
Kdm1b	T	A	13: 47,207,184 (GRCm39)	C169*	probably null	Het
Kmt2c	G	T	5: 25,520,077 (GRCm39)	T2011K	probably benign	Het
Lama1	G	A	17: 68,080,779 (GRCm39)	G1269E		Het
Lamb3	C	T	1: 193,017,182 (GRCm39)	A791V	probably benign	Het
Leng9	G	T	7: 4,151,774 (GRCm39)	R301S	possibly damaging	Het
Lgr6	C	A	1: 134,915,342 (GRCm39)	V746L	probably benign	Het
Lrp5	T	A	19: 3,702,170 (GRCm39)	S216C	probably damaging	Het
Ltn1	T	C	16: 87,178,433 (GRCm39)	T1599A	probably damaging	Het
Map2k1	G	T	9: 64,094,606 (GRCm39)	N345K	probably damaging	Het
Map4k1	T	A	7: 28,688,862 (GRCm39)	D304E	probably benign	Het
Mcpt1	C	T	14: 56,256,522 (GRCm39)	T86I	probably damaging	Het
Mcpt9	T	C	14: 56,265,153 (GRCm39)	K116R	probably benign	Het
Morc2a	G	T	11: 3,628,584 (GRCm39)	A346S	probably damaging	Het
Mybpc3	A	T	2: 90,954,237 (GRCm39)	Q370L	probably benign	Het
Nars2	T	C	7: 96,652,095 (GRCm39)	S229P	probably damaging	Het
Ndufa10	A	T	1: 92,397,693 (GRCm39)	Y118N	probably damaging	Het
Nek11	A	T	9: 105,172,571 (GRCm39)		probably null	Het
Notch4	T	C	17: 34,803,470 (GRCm39)	V1463A	possibly damaging	Het
Nrcam	T	C	12: 44,610,908 (GRCm39)	I536T	probably benign	Het
Or6c202	T	C	10: 128,996,334 (GRCm39)	Y173C	probably benign	Het
Pbld1	A	T	10: 62,912,226 (GRCm39)	T285S	probably benign	Het
Pcdhgb8	A	T	18: 37,896,177 (GRCm39)	T416S	possibly damaging	Het
Plekhg6	T	C	6: 125,351,523 (GRCm39)	D242G	probably damaging	Het
Pnmt	T	A	11: 98,278,580 (GRCm39)	V182D	probably benign	Het
Ppp1r13b	G	T	12: 111,799,871 (GRCm39)	N758K	probably damaging	Het
Prex2	A	G	1: 11,240,799 (GRCm39)		probably benign	Het
Prss3	A	T	6: 41,354,512 (GRCm39)	L7Q	probably damaging	Het
Prss43	T	A	9: 110,660,046 (GRCm39)	L370Q	probably damaging	Het
Rac1	A	T	5: 143,493,885 (GRCm39)	V104E	probably damaging	Het
Rgs9	T	C	11: 109,166,449 (GRCm39)	Y107C	probably damaging	Het
Rnase13	C	T	14: 52,159,940 (GRCm39)	W66*	probably null	Het
Rrp1b	G	A	17: 32,270,688 (GRCm39)	V216I	possibly damaging	Het
Serinc1	A	G	10: 57,395,864 (GRCm39)	S309P	probably benign	Het
Serpine3	T	A	14: 62,902,587 (GRCm39)	L66Q	probably damaging	Het
Smc5	C	T	19: 23,191,234 (GRCm39)	V924M	probably damaging	Het
Spmip4	A	T	6: 50,551,028 (GRCm39)	Y474N	possibly damaging	Het
Srgap1	A	T	10: 121,761,545 (GRCm39)		probably benign	Het
Stab1	T	C	14: 30,883,771 (GRCm39)	E262G	possibly damaging	Het
Ston2	A	G	12: 91,606,498 (GRCm39)	*896R	probably null	Het
Syt6	A	G	3: 103,532,941 (GRCm39)	M442V	probably benign	Het
Tap1	T	C	17: 34,408,536 (GRCm39)		probably null	Het
Tbx3	A	C	5: 119,818,624 (GRCm39)	S420R	probably benign	Het
Tespa1	A	T	10: 130,198,316 (GRCm39)	Q446L	probably benign	Het
Tifab	T	C	13: 56,324,108 (GRCm39)	M112V	probably benign	Het
Trpv5	A	T	6: 41,630,192 (GRCm39)	S633T	possibly damaging	Het
Ttn	T	C	2: 76,684,236 (GRCm39)	K838R	unknown	Het
Ttn	A	T	2: 76,744,810 (GRCm39)	V5413E	probably damaging	Het
Tub	C	A	7: 108,628,793 (GRCm39)	N415K		Het
Vmn2r3	T	C	3: 64,182,383 (GRCm39)	M439V	probably benign	Het
Vps13c	A	G	9: 67,850,736 (GRCm39)	D2231G	probably benign	Het
Wbp1	C	T	6: 83,096,913 (GRCm39)	C118Y	unknown	Het
Zdhhc20	C	T	14: 58,127,671 (GRCm39)		probably benign	Het
Zfp217	T	A	2: 169,956,391 (GRCm39)	N869I	probably benign	Het
Zfp677	T	C	17: 21,618,350 (GRCm39)	I469T	probably benign	Het
Zmym2	T	A	14: 57,185,329 (GRCm39)		probably benign	Het
Zzef1	T	G	11: 72,687,402 (GRCm39)	S94A	probably benign	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,538,128 (GRCm39)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,550,820 (GRCm39)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	119,622,164 (GRCm39)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,525,787 (GRCm39)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,566,943 (GRCm39)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,564,753 (GRCm39)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,542,798 (GRCm39)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,550,874 (GRCm39)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,550,437 (GRCm39)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	119,628,277 (GRCm39)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,550,494 (GRCm39)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,566,802 (GRCm39)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,550,215 (GRCm39)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,565,470 (GRCm39)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,538,137 (GRCm39)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,536,246 (GRCm39)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,564,720 (GRCm39)	missense	probably benign
IGL03404:Dnah3	APN	7	119,538,200 (GRCm39)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	119,618,924 (GRCm39)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	119,676,998 (GRCm39)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	119,644,882 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,564,882 (GRCm39)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,542,795 (GRCm39)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,527,977 (GRCm39)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	119,671,110 (GRCm39)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	119,620,138 (GRCm39)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,567,128 (GRCm39)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	119,629,274 (GRCm39)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R0972:Dnah3	UTSW	7	119,634,563 (GRCm39)	splice site	probably null
R1066:Dnah3	UTSW	7	119,660,232 (GRCm39)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	119,677,668 (GRCm39)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,522,253 (GRCm39)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,538,227 (GRCm39)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	119,689,899 (GRCm39)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,551,202 (GRCm39)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	119,646,853 (GRCm39)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	119,670,181 (GRCm39)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	119,618,918 (GRCm39)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,525,672 (GRCm39)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,570,402 (GRCm39)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,527,963 (GRCm39)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	119,645,009 (GRCm39)	splice site	probably null
R1711:Dnah3	UTSW	7	119,677,794 (GRCm39)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	119,634,582 (GRCm39)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,528,079 (GRCm39)	splice site	probably null
R1883:Dnah3	UTSW	7	119,677,142 (GRCm39)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	119,685,557 (GRCm39)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,567,182 (GRCm39)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,566,793 (GRCm39)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	119,694,400 (GRCm39)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,550,465 (GRCm39)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	119,638,629 (GRCm39)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,551,132 (GRCm39)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,566,982 (GRCm39)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,551,236 (GRCm39)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,550,792 (GRCm39)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	119,645,011 (GRCm39)	splice site	probably null
R2567:Dnah3	UTSW	7	119,551,920 (GRCm39)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,567,161 (GRCm39)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,550,722 (GRCm39)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,550,338 (GRCm39)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,550,333 (GRCm39)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	119,677,704 (GRCm39)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,550,303 (GRCm39)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	119,682,516 (GRCm39)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	119,628,248 (GRCm39)	nonsense	probably null
R4478:Dnah3	UTSW	7	119,671,086 (GRCm39)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	119,608,554 (GRCm39)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign
R4649:Dnah3	UTSW	7	119,646,921 (GRCm39)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	119,658,589 (GRCm39)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	119,677,169 (GRCm39)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	119,678,629 (GRCm39)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,567,047 (GRCm39)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	119,610,295 (GRCm39)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,550,904 (GRCm39)	nonsense	probably null
R4935:Dnah3	UTSW	7	119,615,700 (GRCm39)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,530,783 (GRCm39)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,555,424 (GRCm39)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,528,002 (GRCm39)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	119,671,128 (GRCm39)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,550,803 (GRCm39)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	119,620,169 (GRCm39)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5069:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5154:Dnah3	UTSW	7	119,551,642 (GRCm39)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	119,631,861 (GRCm39)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	119,620,234 (GRCm39)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,542,871 (GRCm39)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,524,126 (GRCm39)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	119,689,299 (GRCm39)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,570,689 (GRCm39)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,570,844 (GRCm39)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,538,288 (GRCm39)	splice site	probably null
R5673:Dnah3	UTSW	7	119,550,812 (GRCm39)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	119,677,074 (GRCm39)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	119,658,421 (GRCm39)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,577,445 (GRCm39)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	119,689,175 (GRCm39)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,542,822 (GRCm39)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,530,696 (GRCm39)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	119,638,585 (GRCm39)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,538,056 (GRCm39)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,574,331 (GRCm39)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	119,668,927 (GRCm39)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	119,677,724 (GRCm39)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	119,615,749 (GRCm39)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,522,103 (GRCm39)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	119,672,764 (GRCm39)	missense	probably benign
R6004:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,566,745 (GRCm39)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	119,629,254 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	119,685,469 (GRCm39)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,564,711 (GRCm39)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	119,608,607 (GRCm39)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	119,653,856 (GRCm39)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,522,191 (GRCm39)	splice site	probably null
R6447:Dnah3	UTSW	7	119,522,277 (GRCm39)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	119,660,179 (GRCm39)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	119,670,172 (GRCm39)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,522,197 (GRCm39)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,570,950 (GRCm39)	missense	probably benign
R6882:Dnah3	UTSW	7	119,570,407 (GRCm39)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	119,653,824 (GRCm39)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	119,631,977 (GRCm39)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	119,629,233 (GRCm39)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,570,312 (GRCm39)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,521,965 (GRCm39)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	119,670,746 (GRCm39)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	119,631,893 (GRCm39)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,542,856 (GRCm39)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,580,567 (GRCm39)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	119,629,208 (GRCm39)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	119,628,239 (GRCm39)	missense	probably benign
R7375:Dnah3	UTSW	7	119,550,900 (GRCm39)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	119,660,183 (GRCm39)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,565,474 (GRCm39)	missense
R7431:Dnah3	UTSW	7	119,650,967 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	119,660,135 (GRCm39)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	119,672,815 (GRCm39)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,570,817 (GRCm39)	missense	probably benign
R7618:Dnah3	UTSW	7	119,577,601 (GRCm39)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,566,657 (GRCm39)	missense
R7728:Dnah3	UTSW	7	119,538,051 (GRCm39)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,570,438 (GRCm39)	splice site	probably null
R7757:Dnah3	UTSW	7	119,670,793 (GRCm39)	missense	probably benign
R7774:Dnah3	UTSW	7	119,550,975 (GRCm39)	nonsense	probably null
R7804:Dnah3	UTSW	7	119,610,235 (GRCm39)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,551,841 (GRCm39)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,550,927 (GRCm39)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,566,775 (GRCm39)	missense
R7903:Dnah3	UTSW	7	119,641,351 (GRCm39)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	119,677,012 (GRCm39)	missense	probably benign
R8142:Dnah3	UTSW	7	119,660,189 (GRCm39)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,566,837 (GRCm39)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,525,636 (GRCm39)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,550,375 (GRCm39)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	119,671,104 (GRCm39)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,551,728 (GRCm39)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	119,610,253 (GRCm39)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,536,253 (GRCm39)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,550,591 (GRCm39)	missense	probably damaging	1.00
R8912:Dnah3	UTSW	7	119,689,869 (GRCm39)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,549,881 (GRCm39)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,536,294 (GRCm39)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,551,272 (GRCm39)	missense	probably benign
R9053:Dnah3	UTSW	7	119,618,987 (GRCm39)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	119,684,368 (GRCm39)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	119,684,351 (GRCm39)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,566,859 (GRCm39)	missense
R9383:Dnah3	UTSW	7	119,646,819 (GRCm39)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	119,628,205 (GRCm39)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,551,473 (GRCm39)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,551,523 (GRCm39)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	119,644,912 (GRCm39)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	119,650,951 (GRCm39)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	119,670,236 (GRCm39)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,561,356 (GRCm39)	missense
R9633:Dnah3	UTSW	7	119,550,216 (GRCm39)	missense	probably benign
R9654:Dnah3	UTSW	7	119,641,396 (GRCm39)	nonsense	probably null
R9665:Dnah3	UTSW	7	119,644,981 (GRCm39)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	119,677,611 (GRCm39)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,574,299 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	119,610,096 (GRCm39)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,567,026 (GRCm39)	missense
Z1177:Dnah3	UTSW	7	119,607,085 (GRCm39)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,567,124 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- CCCAGTTTTGACTCAGAGTGG -3'
(R):5'- GACAGTGCTGATCTCATGTCTCTC -3'

Sequencing Primer
(F):5'- CCCAGTTTTGACTCAGAGTGGGATAG -3'
(R):5'- CCCTCTTCCACGCTAGGTG -3'

Posted On

2021-08-02