Incidental Mutation 'R8887:Wdr64'
| ID |
677369 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wdr64
|
| Ensembl Gene |
ENSMUSG00000026523 |
| Gene Name |
WD repeat domain 64 |
| Synonyms |
4930415O10Rik, 4930511H01Rik |
| MMRRC Submission |
068752-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R8887 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
175526159-175643300 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 175599850 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Histidine
at position 559
(P559H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128678
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094288]
[ENSMUST00000171939]
[ENSMUST00000194087]
[ENSMUST00000194783]
|
| AlphaFold |
Q9D565 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094288
AA Change: P569H
PolyPhen 2
Score 0.352 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000091846
Gene: ENSMUSG00000026523
AA Change: P569H
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
118 |
159 |
2.65e1 |
SMART |
|
WD40
|
162 |
200 |
2.13e1 |
SMART |
|
low complexity region
|
259 |
271 |
N/A |
INTRINSIC |
|
Blast:WD40
|
277 |
316 |
5e-19 |
BLAST |
|
WD40
|
323 |
361 |
2.4e-1 |
SMART |
|
WD40
|
365 |
404 |
8.29e-1 |
SMART |
|
WD40
|
407 |
449 |
1.7e2 |
SMART |
|
WD40
|
457 |
493 |
1.19e1 |
SMART |
|
WD40
|
497 |
538 |
4.55e-3 |
SMART |
|
WD40
|
643 |
684 |
3.31e0 |
SMART |
|
WD40
|
742 |
806 |
7.4e0 |
SMART |
|
Blast:WD40
|
811 |
851 |
7e-17 |
BLAST |
|
WD40
|
864 |
903 |
4.62e-4 |
SMART |
|
Blast:XPGN
|
921 |
964 |
9e-19 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171939
AA Change: P559H
PolyPhen 2
Score 0.175 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000128678
Gene: ENSMUSG00000026523
AA Change: P559H
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
151 |
190 |
5.73e0 |
SMART |
|
low complexity region
|
249 |
261 |
N/A |
INTRINSIC |
|
Blast:WD40
|
267 |
306 |
4e-19 |
BLAST |
|
WD40
|
313 |
351 |
2.4e-1 |
SMART |
|
WD40
|
355 |
394 |
8.29e-1 |
SMART |
|
WD40
|
397 |
439 |
1.7e2 |
SMART |
|
WD40
|
447 |
483 |
1.19e1 |
SMART |
|
WD40
|
487 |
528 |
4.55e-3 |
SMART |
|
WD40
|
633 |
674 |
3.31e0 |
SMART |
|
WD40
|
732 |
796 |
7.4e0 |
SMART |
|
Blast:WD40
|
801 |
841 |
5e-17 |
BLAST |
|
WD40
|
854 |
893 |
4.62e-4 |
SMART |
|
Blast:XPGN
|
911 |
954 |
1e-18 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000194087
AA Change: P559H
PolyPhen 2
Score 0.460 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000141740
Gene: ENSMUSG00000026523
AA Change: P559H
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
151 |
190 |
3.6e-2 |
SMART |
|
low complexity region
|
249 |
261 |
N/A |
INTRINSIC |
|
Blast:WD40
|
267 |
305 |
5e-19 |
BLAST |
|
WD40
|
313 |
351 |
1.5e-3 |
SMART |
|
WD40
|
355 |
394 |
5.2e-3 |
SMART |
|
WD40
|
397 |
439 |
1.1e0 |
SMART |
|
WD40
|
447 |
483 |
7.6e-2 |
SMART |
|
WD40
|
487 |
528 |
2.9e-5 |
SMART |
|
WD40
|
633 |
674 |
2.1e-2 |
SMART |
|
WD40
|
732 |
796 |
4.7e-2 |
SMART |
|
Blast:WD40
|
801 |
841 |
6e-17 |
BLAST |
|
WD40
|
854 |
893 |
2.9e-6 |
SMART |
|
Blast:XPGN
|
911 |
954 |
1e-18 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194783
AA Change: P118H
PolyPhen 2
Score 0.179 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000141384
Gene: ENSMUSG00000026523
AA Change: P118H
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
6 |
42 |
7.6e-2 |
SMART |
|
WD40
|
46 |
87 |
2.9e-5 |
SMART |
|
WD40
|
192 |
233 |
2.1e-2 |
SMART |
|
WD40
|
291 |
355 |
4.7e-2 |
SMART |
|
Blast:WD40
|
360 |
400 |
4e-17 |
BLAST |
|
WD40
|
413 |
452 |
2.9e-6 |
SMART |
|
Blast:XPGN
|
470 |
519 |
3e-19 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
98% (93/95) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1)
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acsbg2 |
T |
C |
17: 57,175,285 (GRCm39) |
T76A |
probably benign |
Het |
| Actn1 |
A |
G |
12: 80,215,197 (GRCm39) |
C860R |
probably damaging |
Het |
| Adam23 |
T |
A |
1: 63,554,744 (GRCm39) |
L170Q |
probably damaging |
Het |
| Afdn |
C |
T |
17: 14,116,401 (GRCm39) |
R1620* |
probably null |
Het |
| Agfg1 |
A |
G |
1: 82,848,525 (GRCm39) |
|
probably benign |
Het |
| Aire |
A |
G |
10: 77,870,298 (GRCm39) |
S476P |
probably damaging |
Het |
| Arhgef26 |
A |
G |
3: 62,247,401 (GRCm39) |
T162A |
probably benign |
Het |
| Atp1a2 |
T |
C |
1: 172,113,222 (GRCm39) |
Q487R |
probably null |
Het |
| BC048507 |
T |
A |
13: 68,011,628 (GRCm39) |
C2S |
probably benign |
Het |
| Bltp1 |
G |
T |
3: 37,087,503 (GRCm39) |
A615S |
possibly damaging |
Het |
| Bnc2 |
A |
C |
4: 84,209,707 (GRCm39) |
|
probably benign |
Het |
| Bop1 |
C |
T |
15: 76,338,524 (GRCm39) |
G473R |
probably damaging |
Het |
| C1galt1 |
A |
G |
6: 7,866,379 (GRCm39) |
E75G |
probably benign |
Het |
| Cacna1i |
T |
C |
15: 80,258,894 (GRCm39) |
V1201A |
possibly damaging |
Het |
| Cecr2 |
C |
A |
6: 120,715,162 (GRCm39) |
T249K |
probably damaging |
Het |
| Clca3a2 |
C |
A |
3: 144,790,810 (GRCm39) |
G421* |
probably null |
Het |
| Clec1b |
A |
T |
6: 129,378,703 (GRCm39) |
|
probably null |
Het |
| Cnksr3 |
C |
T |
10: 7,104,467 (GRCm39) |
D79N |
probably damaging |
Het |
| Col15a1 |
A |
G |
4: 47,287,091 (GRCm39) |
Q843R |
probably damaging |
Het |
| Col6a3 |
T |
C |
1: 90,755,948 (GRCm39) |
S114G |
probably benign |
Het |
| Corin |
A |
T |
5: 72,486,953 (GRCm39) |
|
probably null |
Het |
| Cyp2u1 |
A |
G |
3: 131,096,503 (GRCm39) |
Y92H |
probably damaging |
Het |
| Dcbld2 |
T |
C |
16: 58,229,270 (GRCm39) |
L51P |
probably damaging |
Het |
| Dip2c |
T |
A |
13: 9,673,989 (GRCm39) |
|
probably benign |
Het |
| Dlc1 |
A |
T |
8: 37,051,481 (GRCm39) |
V299E |
probably benign |
Het |
| Dlgap2 |
G |
A |
8: 14,229,682 (GRCm39) |
|
probably null |
Het |
| Dnah1 |
A |
G |
14: 31,032,997 (GRCm39) |
L346P |
probably damaging |
Het |
| Dnah9 |
T |
C |
11: 65,746,210 (GRCm39) |
T3968A |
probably benign |
Het |
| Duox2 |
A |
C |
2: 122,120,044 (GRCm39) |
M822R |
probably null |
Het |
| E2f7 |
A |
T |
10: 110,610,674 (GRCm39) |
Q433L |
probably benign |
Het |
| Eif3k |
A |
C |
7: 28,679,901 (GRCm39) |
Y42* |
probably null |
Het |
| Elmod3 |
A |
G |
6: 72,563,494 (GRCm39) |
S45P |
probably damaging |
Het |
| Emilin3 |
C |
A |
2: 160,751,108 (GRCm39) |
V214F |
possibly damaging |
Het |
| Fbxo10 |
A |
T |
4: 45,058,887 (GRCm39) |
F283L |
probably benign |
Het |
| Fbxw7 |
T |
C |
3: 84,876,549 (GRCm39) |
Y358H |
|
Het |
| G430095P16Rik |
A |
G |
8: 85,453,043 (GRCm39) |
N10S |
unknown |
Het |
| Gldc |
A |
G |
19: 30,111,156 (GRCm39) |
V540A |
possibly damaging |
Het |
| Gm3667 |
T |
A |
14: 18,271,553 (GRCm39) |
E67D |
probably benign |
Het |
| Golga3 |
T |
A |
5: 110,353,626 (GRCm39) |
|
probably benign |
Het |
| H60c |
T |
C |
10: 3,217,255 (GRCm39) |
E38G |
probably benign |
Het |
| Hectd4 |
A |
G |
5: 121,433,541 (GRCm39) |
D952G |
probably benign |
Het |
| Hoxb8 |
T |
A |
11: 96,175,223 (GRCm39) |
L220Q |
probably damaging |
Het |
| Ice1 |
A |
T |
13: 70,751,050 (GRCm39) |
L1679M |
probably damaging |
Het |
| Ifi202b |
T |
A |
1: 173,802,480 (GRCm39) |
Y118F |
probably damaging |
Het |
| Ift122 |
A |
T |
6: 115,868,880 (GRCm39) |
T456S |
probably benign |
Het |
| Ighg3 |
G |
A |
12: 113,323,845 (GRCm39) |
T181I |
|
Het |
| Ighv1-66 |
C |
A |
12: 115,557,032 (GRCm39) |
V17F |
probably damaging |
Het |
| Ighv5-12-4 |
A |
G |
12: 113,726,130 (GRCm39) |
V31A |
possibly damaging |
Het |
| Ints12 |
T |
A |
3: 132,815,003 (GRCm39) |
N403K |
probably damaging |
Het |
| Itpr3 |
G |
A |
17: 27,337,651 (GRCm39) |
|
probably benign |
Het |
| Kalrn |
A |
C |
16: 34,047,496 (GRCm39) |
N908K |
probably benign |
Het |
| Kctd9 |
G |
A |
14: 67,962,016 (GRCm39) |
V20I |
unknown |
Het |
| Krt78 |
G |
T |
15: 101,861,746 (GRCm39) |
L167M |
probably damaging |
Het |
| Ldb1 |
T |
C |
19: 46,023,294 (GRCm39) |
E206G |
probably damaging |
Het |
| Lig1 |
A |
G |
7: 13,030,713 (GRCm39) |
Y455C |
probably damaging |
Het |
| Ltbp1 |
T |
G |
17: 75,486,077 (GRCm39) |
I34S |
probably damaging |
Het |
| Map2 |
T |
C |
1: 66,454,758 (GRCm39) |
I1216T |
possibly damaging |
Het |
| Mex3c |
T |
C |
18: 73,706,800 (GRCm39) |
V229A |
probably damaging |
Het |
| Mfsd11 |
T |
C |
11: 116,745,526 (GRCm39) |
|
probably null |
Het |
| Mroh1 |
A |
G |
15: 76,331,474 (GRCm39) |
T1233A |
probably benign |
Het |
| Myct1 |
C |
T |
10: 5,554,208 (GRCm39) |
T25I |
probably damaging |
Het |
| Nipbl |
A |
T |
15: 8,391,271 (GRCm39) |
H234Q |
probably damaging |
Het |
| Npc1l1 |
G |
A |
11: 6,175,665 (GRCm39) |
P549S |
probably damaging |
Het |
| Or12d2 |
A |
T |
17: 37,624,642 (GRCm39) |
L211Q |
probably damaging |
Het |
| Or4c3 |
A |
G |
2: 89,852,269 (GRCm39) |
V47A |
probably benign |
Het |
| Or5h22 |
A |
T |
16: 58,894,846 (GRCm39) |
V199D |
possibly damaging |
Het |
| Or5w22 |
A |
G |
2: 87,363,187 (GRCm39) |
D270G |
possibly damaging |
Het |
| Or6c3b |
A |
T |
10: 129,527,372 (GRCm39) |
Y179* |
probably null |
Het |
| Padi3 |
A |
T |
4: 140,523,795 (GRCm39) |
C228* |
probably null |
Het |
| Palld |
T |
A |
8: 61,986,512 (GRCm39) |
D1015V |
unknown |
Het |
| Pcna-ps2 |
A |
T |
19: 9,261,488 (GRCm39) |
Y249F |
probably benign |
Het |
| Pelo |
C |
T |
13: 115,225,451 (GRCm39) |
C258Y |
probably benign |
Het |
| Ppp1r13b |
A |
T |
12: 111,803,430 (GRCm39) |
|
probably benign |
Het |
| Pramel26 |
A |
G |
4: 143,539,257 (GRCm39) |
F79L |
probably damaging |
Het |
| Prdm2 |
A |
G |
4: 142,860,771 (GRCm39) |
W840R |
probably damaging |
Het |
| Prkcg |
A |
G |
7: 3,370,857 (GRCm39) |
D428G |
possibly damaging |
Het |
| Pus7 |
G |
A |
5: 23,948,476 (GRCm39) |
R571* |
probably null |
Het |
| Rab11fip3 |
A |
G |
17: 26,286,927 (GRCm39) |
C409R |
possibly damaging |
Het |
| Rdh13 |
T |
C |
7: 4,434,522 (GRCm39) |
D186G |
probably damaging |
Het |
| Rslcan18 |
T |
A |
13: 67,246,793 (GRCm39) |
H273L |
probably damaging |
Het |
| Rxfp1 |
T |
A |
3: 79,559,289 (GRCm39) |
|
probably benign |
Het |
| Sh3bp1 |
T |
A |
15: 78,788,540 (GRCm39) |
|
probably null |
Het |
| Siglecg |
T |
A |
7: 43,058,008 (GRCm39) |
S9T |
probably benign |
Het |
| Slc9a1 |
T |
C |
4: 133,139,258 (GRCm39) |
F159L |
probably benign |
Het |
| Slc9a2 |
A |
G |
1: 40,758,009 (GRCm39) |
I183V |
probably benign |
Het |
| St6galnac4 |
A |
G |
2: 32,484,110 (GRCm39) |
M103V |
probably damaging |
Het |
| Tbc1d30 |
T |
C |
10: 121,187,059 (GRCm39) |
D42G |
possibly damaging |
Het |
| Tlr5 |
C |
A |
1: 182,801,332 (GRCm39) |
T212K |
probably benign |
Het |
| Trim43b |
T |
G |
9: 88,969,642 (GRCm39) |
I269L |
probably benign |
Het |
| Ttll6 |
T |
C |
11: 96,047,492 (GRCm39) |
L697P |
possibly damaging |
Het |
| Ttn |
T |
G |
2: 76,549,239 (GRCm39) |
T31813P |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,571,932 (GRCm39) |
D26320E |
probably damaging |
Het |
| Uba6 |
A |
G |
5: 86,307,061 (GRCm39) |
|
probably null |
Het |
| Usp1 |
C |
G |
4: 98,819,185 (GRCm39) |
Q216E |
probably benign |
Het |
| Vcan |
T |
C |
13: 89,853,026 (GRCm39) |
T645A |
probably benign |
Het |
| Zfat |
T |
C |
15: 68,056,315 (GRCm39) |
Y247C |
probably damaging |
Het |
| Zfp979 |
A |
T |
4: 147,698,219 (GRCm39) |
N163K |
probably damaging |
Het |
|
| Other mutations in Wdr64 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00563:Wdr64
|
APN |
1 |
175,526,366 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00902:Wdr64
|
APN |
1 |
175,556,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01347:Wdr64
|
APN |
1 |
175,547,899 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL01353:Wdr64
|
APN |
1 |
175,559,151 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01583:Wdr64
|
APN |
1 |
175,594,722 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01643:Wdr64
|
APN |
1 |
175,599,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01673:Wdr64
|
APN |
1 |
175,627,922 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL01992:Wdr64
|
APN |
1 |
175,533,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Wdr64
|
APN |
1 |
175,594,613 (GRCm39) |
nonsense |
probably null |
|
|
IGL02834:Wdr64
|
APN |
1 |
175,633,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL03214:Wdr64
|
APN |
1 |
175,571,201 (GRCm39) |
splice site |
probably benign |
|
|
IGL03305:Wdr64
|
APN |
1 |
175,583,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03308:Wdr64
|
APN |
1 |
175,594,562 (GRCm39) |
unclassified |
probably benign |
|
|
PIT4418001:Wdr64
|
UTSW |
1 |
175,571,160 (GRCm39) |
nonsense |
probably null |
|
|
R0036:Wdr64
|
UTSW |
1 |
175,556,496 (GRCm39) |
nonsense |
probably null |
|
|
R0041:Wdr64
|
UTSW |
1 |
175,554,037 (GRCm39) |
nonsense |
probably null |
|
|
R0041:Wdr64
|
UTSW |
1 |
175,554,037 (GRCm39) |
nonsense |
probably null |
|
|
R0079:Wdr64
|
UTSW |
1 |
175,622,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0380:Wdr64
|
UTSW |
1 |
175,597,208 (GRCm39) |
splice site |
probably benign |
|
|
R0486:Wdr64
|
UTSW |
1 |
175,622,769 (GRCm39) |
splice site |
probably benign |
|
|
R0520:Wdr64
|
UTSW |
1 |
175,553,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0598:Wdr64
|
UTSW |
1 |
175,633,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Wdr64
|
UTSW |
1 |
175,599,751 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0746:Wdr64
|
UTSW |
1 |
175,620,539 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0927:Wdr64
|
UTSW |
1 |
175,620,647 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0947:Wdr64
|
UTSW |
1 |
175,603,315 (GRCm39) |
missense |
probably benign |
|
|
R1014:Wdr64
|
UTSW |
1 |
175,583,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1332:Wdr64
|
UTSW |
1 |
175,622,706 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1416:Wdr64
|
UTSW |
1 |
175,633,568 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1421:Wdr64
|
UTSW |
1 |
175,594,716 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1467:Wdr64
|
UTSW |
1 |
175,603,288 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1467:Wdr64
|
UTSW |
1 |
175,603,288 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1796:Wdr64
|
UTSW |
1 |
175,544,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1797:Wdr64
|
UTSW |
1 |
175,639,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Wdr64
|
UTSW |
1 |
175,594,661 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2321:Wdr64
|
UTSW |
1 |
175,622,653 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R2449:Wdr64
|
UTSW |
1 |
175,526,479 (GRCm39) |
missense |
probably benign |
|
|
R4049:Wdr64
|
UTSW |
1 |
175,633,422 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4155:Wdr64
|
UTSW |
1 |
175,597,172 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4624:Wdr64
|
UTSW |
1 |
175,599,829 (GRCm39) |
missense |
probably benign |
|
|
R4661:Wdr64
|
UTSW |
1 |
175,554,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4711:Wdr64
|
UTSW |
1 |
175,626,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4891:Wdr64
|
UTSW |
1 |
175,526,345 (GRCm39) |
unclassified |
probably benign |
|
|
R4925:Wdr64
|
UTSW |
1 |
175,552,268 (GRCm39) |
splice site |
probably null |
|
|
R4943:Wdr64
|
UTSW |
1 |
175,547,882 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5000:Wdr64
|
UTSW |
1 |
175,553,941 (GRCm39) |
splice site |
probably null |
|
|
R5001:Wdr64
|
UTSW |
1 |
175,620,525 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5143:Wdr64
|
UTSW |
1 |
175,553,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5395:Wdr64
|
UTSW |
1 |
175,583,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Wdr64
|
UTSW |
1 |
175,639,623 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6014:Wdr64
|
UTSW |
1 |
175,633,556 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6417:Wdr64
|
UTSW |
1 |
175,553,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6456:Wdr64
|
UTSW |
1 |
175,613,175 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6555:Wdr64
|
UTSW |
1 |
175,547,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6576:Wdr64
|
UTSW |
1 |
175,633,494 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6797:Wdr64
|
UTSW |
1 |
175,638,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6891:Wdr64
|
UTSW |
1 |
175,533,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Wdr64
|
UTSW |
1 |
175,533,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7205:Wdr64
|
UTSW |
1 |
175,617,499 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7252:Wdr64
|
UTSW |
1 |
175,603,240 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7552:Wdr64
|
UTSW |
1 |
175,613,147 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7732:Wdr64
|
UTSW |
1 |
175,617,495 (GRCm39) |
missense |
probably benign |
|
|
R7777:Wdr64
|
UTSW |
1 |
175,617,564 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7780:Wdr64
|
UTSW |
1 |
175,556,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7810:Wdr64
|
UTSW |
1 |
175,559,092 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7833:Wdr64
|
UTSW |
1 |
175,591,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7843:Wdr64
|
UTSW |
1 |
175,639,668 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7887:Wdr64
|
UTSW |
1 |
175,613,111 (GRCm39) |
missense |
not run |
|
|
R7991:Wdr64
|
UTSW |
1 |
175,554,051 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8124:Wdr64
|
UTSW |
1 |
175,626,844 (GRCm39) |
splice site |
probably null |
|
|
R8129:Wdr64
|
UTSW |
1 |
175,603,154 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8673:Wdr64
|
UTSW |
1 |
175,633,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8728:Wdr64
|
UTSW |
1 |
175,559,079 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8786:Wdr64
|
UTSW |
1 |
175,636,327 (GRCm39) |
nonsense |
probably null |
|
|
R8822:Wdr64
|
UTSW |
1 |
175,544,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8842:Wdr64
|
UTSW |
1 |
175,599,893 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9014:Wdr64
|
UTSW |
1 |
175,526,395 (GRCm39) |
missense |
probably benign |
|
|
R9330:Wdr64
|
UTSW |
1 |
175,554,024 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9332:Wdr64
|
UTSW |
1 |
175,599,871 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9465:Wdr64
|
UTSW |
1 |
175,618,823 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9716:Wdr64
|
UTSW |
1 |
175,622,658 (GRCm39) |
missense |
probably benign |
|
|
R9717:Wdr64
|
UTSW |
1 |
175,544,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Wdr64
|
UTSW |
1 |
175,533,551 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAAGAGTCTGGCTGTGTGCAC -3'
(R):5'- CCAGTTAGTGGGTAAGGACTATCC -3'
Sequencing Primer
(F):5'- TGGCTGTGTGCACACCATC -3'
(R):5'- TTGAGGCCTTAGACTCAAGC -3'
|
| Posted On |
2021-08-02 |
Incidental Mutation