Incidental Mutation 'R8896:Megf6'
| ID |
678016 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Megf6
|
| Ensembl Gene |
ENSMUSG00000057751 |
| Gene Name |
multiple EGF-like-domains 6 |
| Synonyms |
2600001P17Rik, Egfl3 |
| MMRRC Submission |
068698-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8896 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
154255187-154360170 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 154326860 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 163
(D163E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000030897
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030897]
[ENSMUST00000152159]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000030897
AA Change: D163E
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000030897
Gene: ENSMUSG00000057751
AA Change: D163E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
EGF_CA
|
122 |
162 |
1.54e-6 |
SMART |
|
EGF_CA
|
163 |
203 |
2.08e-12 |
SMART |
|
EGF
|
207 |
245 |
5.4e-2 |
SMART |
|
EGF
|
249 |
286 |
2.39e-3 |
SMART |
|
EGF_CA
|
287 |
327 |
4.96e-10 |
SMART |
|
EGF
|
336 |
373 |
1.64e-1 |
SMART |
|
EGF
|
377 |
413 |
1.99e1 |
SMART |
|
EGF_CA
|
414 |
454 |
7.4e-9 |
SMART |
|
EGF
|
521 |
554 |
4.26e0 |
SMART |
|
EGF_Lam
|
570 |
609 |
1.19e-3 |
SMART |
|
EGF_like
|
613 |
652 |
5.29e-1 |
SMART |
|
EGF
|
642 |
685 |
2.2e1 |
SMART |
|
EGF_Lam
|
656 |
697 |
1.04e-3 |
SMART |
|
EGF
|
687 |
730 |
1.59e1 |
SMART |
|
EGF_like
|
701 |
742 |
2.27e0 |
SMART |
|
EGF_Lam
|
746 |
784 |
1.33e-1 |
SMART |
|
EGF
|
783 |
816 |
2.85e-1 |
SMART |
|
EGF_Lam
|
832 |
871 |
3.88e-3 |
SMART |
|
EGF_Lam
|
875 |
915 |
3.25e-5 |
SMART |
|
EGF
|
914 |
946 |
4.7e-2 |
SMART |
|
EGF_like
|
962 |
1001 |
1.69e-1 |
SMART |
|
EGF
|
1000 |
1032 |
7.02e-1 |
SMART |
|
EGF_Lam
|
1048 |
1087 |
3.1e-2 |
SMART |
|
EGF
|
1077 |
1118 |
7.53e-1 |
SMART |
|
EGF_like
|
1091 |
1130 |
5.59e-1 |
SMART |
|
EGF
|
1129 |
1161 |
5.04e-2 |
SMART |
|
EGF_Lam
|
1177 |
1216 |
2.94e-3 |
SMART |
|
EGF
|
1206 |
1248 |
1.87e1 |
SMART |
|
EGF_Lam
|
1220 |
1260 |
3.1e-2 |
SMART |
|
EGF
|
1259 |
1291 |
1.73e0 |
SMART |
|
EGF
|
1302 |
1334 |
6.55e-1 |
SMART |
|
EGF
|
1345 |
1377 |
4.39e-2 |
SMART |
|
EGF_Lam
|
1393 |
1432 |
7.64e-2 |
SMART |
|
EGF_Lam
|
1436 |
1475 |
2.64e-5 |
SMART |
|
EGF_like
|
1465 |
1506 |
4.2e1 |
SMART |
|
EGF_Lam
|
1479 |
1518 |
1.19e-3 |
SMART |
|
EGF
|
1517 |
1549 |
1.84e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000152159
AA Change: D55E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000121641
Gene: ENSMUSG00000057751
AA Change: D55E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
EGF_CA
|
55 |
95 |
2.08e-12 |
SMART |
|
EGF
|
99 |
137 |
5.4e-2 |
SMART |
|
EGF
|
141 |
178 |
2.39e-3 |
SMART |
|
EGF_CA
|
179 |
219 |
4.96e-10 |
SMART |
|
EGF
|
228 |
265 |
1.64e-1 |
SMART |
|
EGF
|
269 |
305 |
1.99e1 |
SMART |
|
EGF_CA
|
306 |
346 |
7.4e-9 |
SMART |
|
EGF
|
413 |
446 |
4.26e0 |
SMART |
|
EGF_Lam
|
462 |
501 |
1.19e-3 |
SMART |
|
EGF_like
|
505 |
544 |
5.29e-1 |
SMART |
|
EGF
|
534 |
577 |
2.2e1 |
SMART |
|
EGF_Lam
|
548 |
589 |
1.04e-3 |
SMART |
|
EGF
|
579 |
622 |
1.59e1 |
SMART |
|
EGF_like
|
593 |
634 |
2.27e0 |
SMART |
|
EGF_Lam
|
638 |
676 |
1.33e-1 |
SMART |
|
EGF
|
675 |
708 |
2.85e-1 |
SMART |
|
EGF_Lam
|
724 |
763 |
3.88e-3 |
SMART |
|
EGF_Lam
|
767 |
807 |
3.25e-5 |
SMART |
|
EGF
|
806 |
838 |
4.7e-2 |
SMART |
|
EGF_Lam
|
854 |
893 |
2.56e-3 |
SMART |
|
EGF
|
892 |
924 |
2.02e-1 |
SMART |
|
EGF
|
935 |
967 |
7.13e-2 |
SMART |
|
EGF
|
978 |
1010 |
1.73e0 |
SMART |
|
EGF
|
1021 |
1053 |
6.55e-1 |
SMART |
|
EGF
|
1064 |
1096 |
4.39e-2 |
SMART |
|
EGF
|
1107 |
1139 |
4.97e-1 |
SMART |
|
EGF
|
1159 |
1191 |
1.84e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (73/73) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aox4 |
T |
G |
1: 58,291,233 (GRCm39) |
S784A |
probably benign |
Het |
| Ap3d1 |
T |
A |
10: 80,552,425 (GRCm39) |
H581L |
probably benign |
Het |
| Atp11a |
T |
C |
8: 12,899,781 (GRCm39) |
Y915H |
probably damaging |
Het |
| Atp4b |
T |
C |
8: 13,437,514 (GRCm39) |
D213G |
probably benign |
Het |
| Bcl11a |
A |
G |
11: 24,113,640 (GRCm39) |
S328G |
probably benign |
Het |
| Bean1 |
CT |
C |
8: 104,908,664 (GRCm39) |
|
probably null |
Het |
| Cadps2 |
T |
A |
6: 23,410,876 (GRCm39) |
Y685F |
probably damaging |
Het |
| Ccdc88b |
C |
T |
19: 6,831,203 (GRCm39) |
A580T |
probably benign |
Het |
| Cdc42bpa |
GACAACA |
GACA |
1: 179,958,373 (GRCm39) |
|
probably benign |
Het |
| Cep152 |
A |
T |
2: 125,408,155 (GRCm39) |
V1396D |
possibly damaging |
Het |
| Ces1c |
T |
C |
8: 93,833,254 (GRCm39) |
I404V |
probably benign |
Het |
| Cr2 |
A |
T |
1: 194,851,581 (GRCm39) |
M137K |
possibly damaging |
Het |
| Cyp2d40 |
T |
C |
15: 82,644,454 (GRCm39) |
Y257C |
unknown |
Het |
| Dennd1c |
T |
A |
17: 57,381,512 (GRCm39) |
D116V |
probably damaging |
Het |
| Dph2 |
G |
A |
4: 117,747,575 (GRCm39) |
R270* |
probably null |
Het |
| Dpp8 |
A |
C |
9: 64,985,318 (GRCm39) |
H792P |
possibly damaging |
Het |
| Dusp29 |
T |
C |
14: 21,736,763 (GRCm39) |
D113G |
probably benign |
Het |
| Efs |
T |
C |
14: 55,157,756 (GRCm39) |
E185G |
possibly damaging |
Het |
| Eml3 |
A |
G |
19: 8,914,056 (GRCm39) |
E480G |
probably damaging |
Het |
| Fam193a |
A |
G |
5: 34,583,828 (GRCm39) |
T336A |
probably benign |
Het |
| Fermt1 |
C |
T |
2: 132,783,852 (GRCm39) |
|
probably benign |
Het |
| Galnt4 |
T |
A |
10: 98,945,955 (GRCm39) |
V560D |
probably damaging |
Het |
| Gbp2b |
C |
A |
3: 142,309,327 (GRCm39) |
T146K |
probably damaging |
Het |
| Gbp5 |
C |
T |
3: 142,211,308 (GRCm39) |
T346I |
probably damaging |
Het |
| Glrx |
G |
T |
13: 75,995,317 (GRCm39) |
C79F |
probably damaging |
Het |
| Glt8d2 |
T |
A |
10: 82,490,616 (GRCm39) |
T225S |
probably damaging |
Het |
| Grm3 |
A |
G |
5: 9,562,483 (GRCm39) |
F456L |
possibly damaging |
Het |
| Gse1 |
T |
G |
8: 121,303,185 (GRCm39) |
S1109A |
unknown |
Het |
| Gstp3 |
A |
T |
19: 4,108,573 (GRCm39) |
L63Q |
probably damaging |
Het |
| Hapln3 |
G |
A |
7: 78,767,239 (GRCm39) |
R267W |
probably benign |
Het |
| Herc4 |
T |
A |
10: 63,147,286 (GRCm39) |
I801N |
possibly damaging |
Het |
| Ido1 |
G |
T |
8: 25,077,880 (GRCm39) |
D153E |
probably benign |
Het |
| Itpr3 |
G |
A |
17: 27,337,651 (GRCm39) |
|
probably benign |
Het |
| Kcnj9 |
T |
A |
1: 172,153,360 (GRCm39) |
S255C |
probably damaging |
Het |
| Kpna3 |
T |
C |
14: 61,629,294 (GRCm39) |
N39D |
probably benign |
Het |
| Krt39 |
A |
T |
11: 99,409,095 (GRCm39) |
S269T |
probably damaging |
Het |
| Lfng |
G |
A |
5: 140,598,978 (GRCm39) |
V296I |
probably benign |
Het |
| Lrit3 |
T |
A |
3: 129,585,132 (GRCm39) |
I209F |
probably damaging |
Het |
| Map4k5 |
T |
A |
12: 69,870,275 (GRCm39) |
D523V |
possibly damaging |
Het |
| Mdn1 |
C |
T |
4: 32,678,328 (GRCm39) |
P652L |
probably benign |
Het |
| Med30 |
G |
A |
15: 52,584,516 (GRCm39) |
V145I |
possibly damaging |
Het |
| Meltf |
T |
A |
16: 31,709,522 (GRCm39) |
|
probably benign |
Het |
| Mindy4 |
T |
C |
6: 55,255,223 (GRCm39) |
L567P |
probably benign |
Het |
| Mppe1 |
T |
C |
18: 67,370,472 (GRCm39) |
D75G |
probably damaging |
Het |
| Muc4 |
C |
T |
16: 32,754,673 (GRCm38) |
P1516S |
probably benign |
Het |
| Myo3b |
C |
A |
2: 70,069,160 (GRCm39) |
F494L |
probably damaging |
Het |
| Nedd4l |
A |
G |
18: 65,298,688 (GRCm39) |
T226A |
probably benign |
Het |
| Nod1 |
A |
G |
6: 54,921,277 (GRCm39) |
V347A |
probably benign |
Het |
| Nup210 |
A |
T |
6: 91,019,235 (GRCm39) |
|
probably null |
Het |
| Nup210l |
A |
G |
3: 90,025,932 (GRCm39) |
R185G |
probably damaging |
Het |
| Oma1 |
T |
C |
4: 103,210,829 (GRCm39) |
L445S |
probably damaging |
Het |
| Or13p10 |
A |
T |
4: 118,523,502 (GRCm39) |
M263L |
probably benign |
Het |
| Or5ac20 |
A |
T |
16: 59,104,452 (GRCm39) |
M136K |
probably damaging |
Het |
| Or8g36 |
A |
G |
9: 39,422,770 (GRCm39) |
L82P |
probably damaging |
Het |
| Oxsm |
A |
T |
14: 16,242,677 (GRCm38) |
F31I |
probably benign |
Het |
| Pdcd5 |
A |
T |
7: 35,346,795 (GRCm39) |
M1K |
probably null |
Het |
| Pkd1l2 |
T |
C |
8: 117,740,615 (GRCm39) |
T2161A |
possibly damaging |
Het |
| Pla2g3 |
A |
T |
11: 3,442,151 (GRCm39) |
S404C |
probably null |
Het |
| Plec |
A |
G |
15: 76,078,560 (GRCm39) |
V60A |
unknown |
Het |
| Prpsap2 |
A |
G |
11: 61,643,736 (GRCm39) |
S66P |
possibly damaging |
Het |
| Rarb |
A |
G |
14: 16,436,804 (GRCm38) |
L239P |
probably damaging |
Het |
| Ryr3 |
A |
T |
2: 112,583,395 (GRCm39) |
Y2845* |
probably null |
Het |
| Spta1 |
T |
C |
1: 174,045,548 (GRCm39) |
C1569R |
probably damaging |
Het |
| Stard13 |
G |
A |
5: 150,986,115 (GRCm39) |
S465L |
probably damaging |
Het |
| Tmub1 |
A |
T |
5: 24,651,680 (GRCm39) |
S80T |
probably benign |
Het |
| Trpv5 |
A |
G |
6: 41,647,847 (GRCm39) |
F322S |
probably damaging |
Het |
| Vmn2r5 |
G |
A |
3: 64,411,203 (GRCm39) |
A455V |
probably benign |
Het |
| Washc4 |
T |
A |
10: 83,405,882 (GRCm39) |
N459K |
probably damaging |
Het |
| Wdr11 |
C |
T |
7: 129,207,437 (GRCm39) |
R300* |
probably null |
Het |
| Zer1 |
A |
G |
2: 29,993,430 (GRCm39) |
F559L |
probably damaging |
Het |
| Zfat |
A |
T |
15: 68,052,519 (GRCm39) |
V425D |
probably damaging |
Het |
| Zfp738 |
G |
A |
13: 67,817,910 (GRCm39) |
L694F |
|
Het |
| Zfp839 |
C |
T |
12: 110,835,277 (GRCm39) |
A844V |
probably damaging |
Het |
|
| Other mutations in Megf6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01122:Megf6
|
APN |
4 |
154,338,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Megf6
|
APN |
4 |
154,337,020 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01512:Megf6
|
APN |
4 |
154,347,040 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01824:Megf6
|
APN |
4 |
154,336,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02172:Megf6
|
APN |
4 |
154,355,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02727:Megf6
|
APN |
4 |
154,337,606 (GRCm39) |
splice site |
probably null |
|
|
IGL02966:Megf6
|
APN |
4 |
154,338,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Didactic
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0118:Megf6
|
UTSW |
4 |
154,339,098 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0220:Megf6
|
UTSW |
4 |
154,342,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Megf6
|
UTSW |
4 |
154,339,092 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0383:Megf6
|
UTSW |
4 |
154,349,783 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0417:Megf6
|
UTSW |
4 |
154,352,424 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0526:Megf6
|
UTSW |
4 |
154,343,398 (GRCm39) |
missense |
probably benign |
|
|
R0528:Megf6
|
UTSW |
4 |
154,343,630 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0928:Megf6
|
UTSW |
4 |
154,261,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1311:Megf6
|
UTSW |
4 |
154,348,239 (GRCm39) |
splice site |
probably null |
|
|
R1458:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1470:Megf6
|
UTSW |
4 |
154,336,876 (GRCm39) |
splice site |
probably benign |
|
|
R1476:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1479:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1624:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1626:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1638:Megf6
|
UTSW |
4 |
154,346,967 (GRCm39) |
splice site |
probably benign |
|
|
R1777:Megf6
|
UTSW |
4 |
154,355,147 (GRCm39) |
nonsense |
probably null |
|
|
R1831:Megf6
|
UTSW |
4 |
154,355,134 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1944:Megf6
|
UTSW |
4 |
154,340,523 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1984:Megf6
|
UTSW |
4 |
154,352,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2448:Megf6
|
UTSW |
4 |
154,351,102 (GRCm39) |
splice site |
probably null |
|
|
R2880:Megf6
|
UTSW |
4 |
154,337,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4032:Megf6
|
UTSW |
4 |
154,261,550 (GRCm39) |
nonsense |
probably null |
|
|
R4058:Megf6
|
UTSW |
4 |
154,326,989 (GRCm39) |
splice site |
probably benign |
|
|
R4672:Megf6
|
UTSW |
4 |
154,333,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4688:Megf6
|
UTSW |
4 |
154,338,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4752:Megf6
|
UTSW |
4 |
154,336,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:Megf6
|
UTSW |
4 |
154,338,738 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4909:Megf6
|
UTSW |
4 |
154,349,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Megf6
|
UTSW |
4 |
154,338,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4981:Megf6
|
UTSW |
4 |
154,351,907 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4990:Megf6
|
UTSW |
4 |
154,351,683 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5001:Megf6
|
UTSW |
4 |
154,352,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5189:Megf6
|
UTSW |
4 |
154,336,980 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5210:Megf6
|
UTSW |
4 |
154,354,273 (GRCm39) |
intron |
probably benign |
|
|
R5220:Megf6
|
UTSW |
4 |
154,338,295 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5250:Megf6
|
UTSW |
4 |
154,340,467 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5697:Megf6
|
UTSW |
4 |
154,342,686 (GRCm39) |
missense |
probably null |
0.15 |
|
R5808:Megf6
|
UTSW |
4 |
154,352,119 (GRCm39) |
missense |
probably benign |
|
|
R5916:Megf6
|
UTSW |
4 |
154,333,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6054:Megf6
|
UTSW |
4 |
154,347,636 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6075:Megf6
|
UTSW |
4 |
154,347,056 (GRCm39) |
nonsense |
probably null |
|
|
R6515:Megf6
|
UTSW |
4 |
154,343,376 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6599:Megf6
|
UTSW |
4 |
154,342,544 (GRCm39) |
splice site |
probably null |
|
|
R6811:Megf6
|
UTSW |
4 |
154,336,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Megf6
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7023:Megf6
|
UTSW |
4 |
154,338,602 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7117:Megf6
|
UTSW |
4 |
154,343,379 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7163:Megf6
|
UTSW |
4 |
154,351,898 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7345:Megf6
|
UTSW |
4 |
154,351,772 (GRCm39) |
missense |
probably benign |
|
|
R7580:Megf6
|
UTSW |
4 |
154,355,201 (GRCm39) |
nonsense |
probably null |
|
|
R7649:Megf6
|
UTSW |
4 |
154,349,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7702:Megf6
|
UTSW |
4 |
154,354,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8010:Megf6
|
UTSW |
4 |
154,354,964 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8175:Megf6
|
UTSW |
4 |
154,353,076 (GRCm39) |
nonsense |
probably null |
|
|
R8231:Megf6
|
UTSW |
4 |
154,336,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8436:Megf6
|
UTSW |
4 |
154,349,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8460:Megf6
|
UTSW |
4 |
154,350,634 (GRCm39) |
nonsense |
probably null |
|
|
R8738:Megf6
|
UTSW |
4 |
154,352,436 (GRCm39) |
missense |
probably benign |
|
|
R8854:Megf6
|
UTSW |
4 |
154,352,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9098:Megf6
|
UTSW |
4 |
154,354,160 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9147:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9148:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9161:Megf6
|
UTSW |
4 |
154,352,172 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9355:Megf6
|
UTSW |
4 |
154,338,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9386:Megf6
|
UTSW |
4 |
154,340,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9404:Megf6
|
UTSW |
4 |
154,348,225 (GRCm39) |
missense |
|
|
|
R9469:Megf6
|
UTSW |
4 |
154,335,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9472:Megf6
|
UTSW |
4 |
154,333,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9777:Megf6
|
UTSW |
4 |
154,343,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Megf6
|
UTSW |
4 |
154,322,283 (GRCm39) |
missense |
probably benign |
0.12 |
|
Z1177:Megf6
|
UTSW |
4 |
154,354,198 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,204 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,139 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Megf6
|
UTSW |
4 |
154,352,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
Z1177:Megf6
|
UTSW |
4 |
154,335,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCTCATGCTGAAATTTCCTC -3'
(R):5'- TGCAGACATGGGTACATTCTGG -3'
Sequencing Primer
(F):5'- ATGCTGAAATTTCCTCTGGTAGC -3'
(R):5'- ACATGGGTACATTCTGGAGAGTG -3'
|
| Posted On |
2021-08-02 |
Incidental Mutation