Incidental Mutation 'R8903:Obsl1'
| ID |
678278 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Obsl1
|
| Ensembl Gene |
ENSMUSG00000026211 |
| Gene Name |
obscurin-like 1 |
| Synonyms |
|
| MMRRC Submission |
068760-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.205)
|
| Stock # |
R8903 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
75462469-75483134 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 75463917 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1696
(V1696A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000050899]
[ENSMUST00000113567]
[ENSMUST00000113575]
[ENSMUST00000148980]
[ENSMUST00000187411]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000050899
|
| SMART Domains |
Protein: ENSMUSP00000057865
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4203
|
40 |
236 |
7.2e-51 |
PFAM |
|
low complexity region
|
252 |
302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113567
AA Change: V1696A
PolyPhen 2
Score 0.655 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109197
Gene: ENSMUSG00000026211
AA Change: V1696A
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
8e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
3e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
IG
|
996 |
1075 |
1.27e-5 |
SMART |
|
IGc2
|
1094 |
1160 |
4.07e-4 |
SMART |
|
IGc2
|
1186 |
1252 |
9.49e-5 |
SMART |
|
IG
|
1274 |
1353 |
7.41e-7 |
SMART |
|
IG
|
1363 |
1444 |
1.15e-3 |
SMART |
|
IG
|
1454 |
1533 |
8.33e-1 |
SMART |
|
IGc2
|
1549 |
1615 |
8.72e-4 |
SMART |
|
IG
|
1633 |
1712 |
1e-3 |
SMART |
|
IG
|
1723 |
1802 |
3.82e-9 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113575
|
| SMART Domains |
Protein: ENSMUSP00000109205
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4203
|
39 |
237 |
2.2e-59 |
PFAM |
|
low complexity region
|
252 |
302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132252
|
| SMART Domains |
Protein: ENSMUSP00000117420
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
1 |
59 |
2.8e-1 |
SMART |
|
IGc2
|
85 |
151 |
9.49e-5 |
SMART |
|
IG
|
175 |
254 |
2.64e-3 |
SMART |
|
IG
|
265 |
344 |
7.41e-7 |
SMART |
|
Blast:IG
|
354 |
417 |
4e-35 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148980
|
| SMART Domains |
Protein: ENSMUSP00000116977
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
19 |
N/A |
INTRINSIC |
|
Pfam:DUF4203
|
119 |
150 |
6.6e-12 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155084
|
| SMART Domains |
Protein: ENSMUSP00000114553
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1g1ca_
|
2 |
32 |
1e-3 |
SMART |
|
IGc2
|
64 |
132 |
1.48e-6 |
SMART |
|
IG
|
153 |
233 |
9.49e-5 |
SMART |
|
IG
|
241 |
317 |
1.04e-1 |
SMART |
|
FN3
|
324 |
407 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
414 |
520 |
4e-57 |
PDB |
|
Blast:IG_like
|
428 |
517 |
2e-50 |
BLAST |
|
IG
|
529 |
610 |
3.79e-4 |
SMART |
|
IG
|
620 |
699 |
2.58e-6 |
SMART |
|
IGc2
|
717 |
783 |
1.12e-6 |
SMART |
|
IG
|
802 |
881 |
1.27e-5 |
SMART |
|
IGc2
|
900 |
966 |
4.07e-4 |
SMART |
|
IGc2
|
992 |
1058 |
9.49e-5 |
SMART |
|
IG
|
1080 |
1159 |
7.41e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187411
|
| SMART Domains |
Protein: ENSMUSP00000140795
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
38 |
50 |
N/A |
INTRINSIC |
|
Pfam:DUF4203
|
101 |
142 |
6.9e-10 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.4%
|
| Validation Efficiency |
97% (74/76) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca14 |
T |
C |
7: 119,815,526 (GRCm39) |
F258S |
probably damaging |
Het |
| Abca3 |
A |
G |
17: 24,602,959 (GRCm39) |
Y518C |
probably damaging |
Het |
| Ank2 |
A |
T |
3: 126,840,431 (GRCm39) |
N274K |
probably damaging |
Het |
| Ankrd31 |
C |
T |
13: 96,969,329 (GRCm39) |
L989F |
probably damaging |
Het |
| Ano6 |
A |
G |
15: 95,825,463 (GRCm39) |
R354G |
probably benign |
Het |
| Ano8 |
T |
C |
8: 71,934,834 (GRCm39) |
|
probably null |
Het |
| Arfgef1 |
T |
C |
1: 10,211,838 (GRCm39) |
Y1735C |
probably damaging |
Het |
| B3gnt8 |
G |
A |
7: 25,328,659 (GRCm39) |
G363D |
probably benign |
Het |
| Calcrl |
T |
C |
2: 84,203,729 (GRCm39) |
|
probably null |
Het |
| Cc2d2b |
A |
T |
19: 40,797,726 (GRCm39) |
D782V |
unknown |
Het |
| Ccdc162 |
A |
G |
10: 41,531,440 (GRCm39) |
|
probably null |
Het |
| Cdkal1 |
A |
T |
13: 29,809,918 (GRCm39) |
*219R |
probably null |
Het |
| Clcnkb |
A |
T |
4: 141,135,160 (GRCm39) |
V526D |
possibly damaging |
Het |
| Cnbp |
A |
T |
6: 87,821,074 (GRCm39) |
C162S |
probably damaging |
Het |
| Coq2 |
A |
G |
5: 100,811,656 (GRCm39) |
|
probably benign |
Het |
| D6Wsu163e |
T |
A |
6: 126,931,778 (GRCm39) |
L270Q |
probably damaging |
Het |
| Dennd10 |
C |
T |
19: 60,823,423 (GRCm39) |
Q353* |
probably null |
Het |
| Dnhd1 |
C |
T |
7: 105,362,855 (GRCm39) |
Q3806* |
probably null |
Het |
| Eepd1 |
T |
C |
9: 25,394,518 (GRCm39) |
F261L |
probably benign |
Het |
| Fes |
C |
T |
7: 80,036,559 (GRCm39) |
|
probably benign |
Het |
| Fsip2 |
T |
A |
2: 82,807,681 (GRCm39) |
D1333E |
possibly damaging |
Het |
| Gm10800 |
CAAGAAAACTGAAAATCAAAGAAAACTGAAAATCA |
CAAGAAAACTGAAAATCA |
2: 98,497,361 (GRCm39) |
|
probably null |
Het |
| Gm5113 |
T |
C |
7: 29,878,292 (GRCm39) |
F127L |
probably benign |
Het |
| Grk3 |
A |
G |
5: 113,066,697 (GRCm39) |
S596P |
possibly damaging |
Het |
| Gsk3a |
A |
G |
7: 24,936,814 (GRCm39) |
V91A |
possibly damaging |
Het |
| Gss |
T |
C |
2: 155,420,279 (GRCm39) |
K141E |
probably damaging |
Het |
| Il1rl2 |
A |
T |
1: 40,366,530 (GRCm39) |
|
probably null |
Het |
| Kcnmb1 |
A |
G |
11: 33,914,825 (GRCm39) |
Y42C |
probably damaging |
Het |
| Krtap16-1 |
A |
T |
11: 99,877,170 (GRCm39) |
I78N |
probably damaging |
Het |
| Lrp2 |
C |
T |
2: 69,379,382 (GRCm39) |
S110N |
possibly damaging |
Het |
| Lrrfip1 |
T |
A |
1: 91,012,781 (GRCm39) |
|
probably benign |
Het |
| Magel2 |
G |
T |
7: 62,029,441 (GRCm39) |
A782S |
unknown |
Het |
| Map1b |
C |
A |
13: 99,569,017 (GRCm39) |
E1235* |
probably null |
Het |
| Mcpt1 |
A |
C |
14: 56,257,520 (GRCm39) |
H222P |
probably benign |
Het |
| Met |
T |
A |
6: 17,549,137 (GRCm39) |
N996K |
probably benign |
Het |
| Mia |
C |
A |
7: 26,880,230 (GRCm39) |
Q52H |
probably damaging |
Het |
| Mia |
T |
A |
7: 26,880,231 (GRCm39) |
Q52L |
possibly damaging |
Het |
| Myh7 |
T |
A |
14: 55,230,228 (GRCm39) |
K35* |
probably null |
Het |
| Myt1l |
T |
A |
12: 29,861,468 (GRCm39) |
D83E |
unknown |
Het |
| Nbl1 |
A |
G |
4: 138,810,861 (GRCm39) |
V111A |
probably damaging |
Het |
| Nid1 |
T |
A |
13: 13,638,515 (GRCm39) |
V145D |
probably benign |
Het |
| Nif3l1 |
C |
T |
1: 58,486,653 (GRCm39) |
|
probably benign |
Het |
| Npnt |
T |
C |
3: 132,591,764 (GRCm39) |
Y500C |
probably damaging |
Het |
| Nubpl |
T |
A |
12: 52,144,676 (GRCm39) |
|
probably null |
Het |
| Nxpe4 |
T |
A |
9: 48,310,250 (GRCm39) |
D504E |
probably damaging |
Het |
| Or56a3 |
A |
T |
7: 104,735,329 (GRCm39) |
R135S |
possibly damaging |
Het |
| Or8s2 |
A |
T |
15: 98,276,475 (GRCm39) |
I172N |
probably damaging |
Het |
| P2rx1 |
A |
T |
11: 72,900,821 (GRCm39) |
H224L |
probably benign |
Het |
| Pald1 |
A |
T |
10: 61,182,815 (GRCm39) |
|
probably null |
Het |
| Pard6g |
C |
T |
18: 80,160,411 (GRCm39) |
R175* |
probably null |
Het |
| Pisd |
A |
G |
5: 32,895,755 (GRCm39) |
I271T |
probably benign |
Het |
| Prrt3 |
T |
C |
6: 113,472,796 (GRCm39) |
S459G |
probably damaging |
Het |
| Psd3 |
A |
T |
8: 68,165,945 (GRCm39) |
C328S |
unknown |
Het |
| Psme1 |
A |
G |
14: 55,817,853 (GRCm39) |
E120G |
|
Het |
| Pum3 |
A |
T |
19: 27,397,457 (GRCm39) |
M306K |
possibly damaging |
Het |
| Pxdn |
T |
C |
12: 30,040,992 (GRCm39) |
F423L |
probably benign |
Het |
| Rac3 |
A |
G |
11: 120,614,071 (GRCm39) |
D118G |
probably damaging |
Het |
| Rnf14 |
A |
G |
18: 38,446,267 (GRCm39) |
K357E |
probably benign |
Het |
| Rpl23a |
T |
C |
11: 78,073,720 (GRCm39) |
I40V |
probably benign |
Het |
| Slc5a5 |
A |
T |
8: 71,345,227 (GRCm39) |
S27T |
probably damaging |
Het |
| Slc7a14 |
A |
T |
3: 31,277,595 (GRCm39) |
L670Q |
probably damaging |
Het |
| Snorc |
C |
T |
1: 87,402,826 (GRCm39) |
T52I |
probably damaging |
Het |
| Sst |
T |
A |
16: 23,708,499 (GRCm39) |
K111* |
probably null |
Het |
| Stxbp4 |
A |
G |
11: 90,426,267 (GRCm39) |
S514P |
unknown |
Het |
| Susd1 |
T |
A |
4: 59,390,576 (GRCm39) |
T300S |
probably benign |
Het |
| Tecpr1 |
C |
T |
5: 144,150,845 (GRCm39) |
|
probably benign |
Het |
| Tmem185b |
C |
T |
1: 119,454,198 (GRCm39) |
|
probably benign |
Het |
| Tor2a |
T |
A |
2: 32,651,699 (GRCm39) |
F305I |
probably damaging |
Het |
| Ttk |
T |
A |
9: 83,750,113 (GRCm39) |
D689E |
probably damaging |
Het |
| Tut4 |
A |
T |
4: 108,336,408 (GRCm39) |
D44V |
probably damaging |
Het |
| Usp25 |
A |
G |
16: 76,878,421 (GRCm39) |
D615G |
probably damaging |
Het |
| Vmn1r209 |
A |
G |
13: 22,990,684 (GRCm39) |
V2A |
probably benign |
Het |
| Vmn2r80 |
A |
C |
10: 79,017,928 (GRCm39) |
E551A |
probably damaging |
Het |
| Wac |
G |
T |
18: 7,926,104 (GRCm39) |
E636* |
probably null |
Het |
| Wdr53 |
T |
A |
16: 32,071,130 (GRCm39) |
D158E |
probably damaging |
Het |
| Zbtb7c |
T |
C |
18: 76,270,152 (GRCm39) |
V80A |
probably damaging |
Het |
|
| Other mutations in Obsl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Obsl1
|
APN |
1 |
75,467,518 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01111:Obsl1
|
APN |
1 |
75,473,789 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01140:Obsl1
|
APN |
1 |
75,466,400 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02149:Obsl1
|
APN |
1 |
75,480,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Obsl1
|
APN |
1 |
75,480,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Obsl1
|
APN |
1 |
75,464,357 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02296:Obsl1
|
APN |
1 |
75,474,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02386:Obsl1
|
APN |
1 |
75,469,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Obsl1
|
APN |
1 |
75,481,890 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02601:Obsl1
|
APN |
1 |
75,466,264 (GRCm39) |
missense |
probably benign |
|
|
IGL03053:Obsl1
|
APN |
1 |
75,469,723 (GRCm39) |
missense |
probably benign |
|
|
IGL03181:Obsl1
|
APN |
1 |
75,469,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03402:Obsl1
|
APN |
1 |
75,463,443 (GRCm39) |
missense |
probably benign |
0.00 |
|
Jude
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Obsl1
|
UTSW |
1 |
75,482,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4382001:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0281:Obsl1
|
UTSW |
1 |
75,469,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1343:Obsl1
|
UTSW |
1 |
75,469,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1394:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1395:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1439:Obsl1
|
UTSW |
1 |
75,463,428 (GRCm39) |
nonsense |
probably null |
|
|
R1456:Obsl1
|
UTSW |
1 |
75,464,300 (GRCm39) |
nonsense |
probably null |
|
|
R1728:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1729:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1730:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1739:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1757:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R1762:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1783:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1784:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1785:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1851:Obsl1
|
UTSW |
1 |
75,469,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Obsl1
|
UTSW |
1 |
75,469,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1873:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Obsl1
|
UTSW |
1 |
75,482,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1985:Obsl1
|
UTSW |
1 |
75,482,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2069:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2122:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R2141:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2142:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2184:Obsl1
|
UTSW |
1 |
75,478,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2267:Obsl1
|
UTSW |
1 |
75,482,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2883:Obsl1
|
UTSW |
1 |
75,473,155 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3079:Obsl1
|
UTSW |
1 |
75,467,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Obsl1
|
UTSW |
1 |
75,474,890 (GRCm39) |
missense |
probably benign |
|
|
R4002:Obsl1
|
UTSW |
1 |
75,476,743 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4365:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4366:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4414:Obsl1
|
UTSW |
1 |
75,467,546 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Obsl1
|
UTSW |
1 |
75,480,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Obsl1
|
UTSW |
1 |
75,466,145 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5081:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5389:Obsl1
|
UTSW |
1 |
75,479,905 (GRCm39) |
intron |
probably benign |
|
|
R5757:Obsl1
|
UTSW |
1 |
75,469,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5890:Obsl1
|
UTSW |
1 |
75,470,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5946:Obsl1
|
UTSW |
1 |
75,467,851 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6005:Obsl1
|
UTSW |
1 |
75,468,859 (GRCm39) |
splice site |
probably null |
|
|
R6118:Obsl1
|
UTSW |
1 |
75,468,722 (GRCm39) |
intron |
probably benign |
|
|
R6154:Obsl1
|
UTSW |
1 |
75,476,788 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6317:Obsl1
|
UTSW |
1 |
75,466,273 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6379:Obsl1
|
UTSW |
1 |
75,479,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6387:Obsl1
|
UTSW |
1 |
75,468,006 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7084:Obsl1
|
UTSW |
1 |
75,464,394 (GRCm39) |
missense |
probably benign |
|
|
R7123:Obsl1
|
UTSW |
1 |
75,466,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7202:Obsl1
|
UTSW |
1 |
75,466,360 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7291:Obsl1
|
UTSW |
1 |
75,466,161 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7305:Obsl1
|
UTSW |
1 |
75,470,590 (GRCm39) |
nonsense |
probably null |
|
|
R7366:Obsl1
|
UTSW |
1 |
75,479,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Obsl1
|
UTSW |
1 |
75,464,348 (GRCm39) |
missense |
probably benign |
|
|
R7474:Obsl1
|
UTSW |
1 |
75,474,828 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7611:Obsl1
|
UTSW |
1 |
75,482,024 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7672:Obsl1
|
UTSW |
1 |
75,469,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7715:Obsl1
|
UTSW |
1 |
75,478,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7762:Obsl1
|
UTSW |
1 |
75,480,167 (GRCm39) |
missense |
probably benign |
|
|
R8005:Obsl1
|
UTSW |
1 |
75,482,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Obsl1
|
UTSW |
1 |
75,469,317 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8379:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8381:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8383:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8396:Obsl1
|
UTSW |
1 |
75,480,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8465:Obsl1
|
UTSW |
1 |
75,480,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Obsl1
|
UTSW |
1 |
75,482,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8710:Obsl1
|
UTSW |
1 |
75,469,326 (GRCm39) |
missense |
probably benign |
|
|
R8877:Obsl1
|
UTSW |
1 |
75,473,167 (GRCm39) |
nonsense |
probably null |
|
|
R8913:Obsl1
|
UTSW |
1 |
75,467,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8924:Obsl1
|
UTSW |
1 |
75,482,841 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8955:Obsl1
|
UTSW |
1 |
75,480,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9008:Obsl1
|
UTSW |
1 |
75,482,027 (GRCm39) |
missense |
probably benign |
|
|
R9121:Obsl1
|
UTSW |
1 |
75,482,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9295:Obsl1
|
UTSW |
1 |
75,476,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Obsl1
|
UTSW |
1 |
75,482,391 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9367:Obsl1
|
UTSW |
1 |
75,466,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9459:Obsl1
|
UTSW |
1 |
75,474,884 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9496:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9497:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Obsl1
|
UTSW |
1 |
75,466,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9546:Obsl1
|
UTSW |
1 |
75,482,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9550:Obsl1
|
UTSW |
1 |
75,474,910 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9561:Obsl1
|
UTSW |
1 |
75,480,157 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9687:Obsl1
|
UTSW |
1 |
75,479,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V8831:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
X0061:Obsl1
|
UTSW |
1 |
75,463,412 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,467,656 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1177:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,480,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGCTGCTCTCTGTGACC -3'
(R):5'- CAGCTCTGAGTTCTGCCTAG -3'
Sequencing Primer
(F):5'- TGTGACCTGCCCCAAGAGAG -3'
(R):5'- GAGTTCTGCCTAGCTCCTCTTCG -3'
|
| Posted On |
2021-08-02 |
Incidental Mutation