Incidental Mutation 'R8919:Dab2'
| ID |
679158 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dab2
|
| Ensembl Gene |
ENSMUSG00000022150 |
| Gene Name |
disabled 2, mitogen-responsive phosphoprotein |
| Synonyms |
5730435J12Rik, D15Wsu122e, D630005B22Rik, p96 |
| MMRRC Submission |
068706-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.914)
|
| Stock # |
R8919 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
6329269-6470193 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 6465271 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 707
(N707K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079689
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078019]
[ENSMUST00000080880]
[ENSMUST00000110663]
[ENSMUST00000110664]
[ENSMUST00000161812]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000078019
AA Change: N489K
PolyPhen 2
Score 0.146 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000077166
Gene: ENSMUSG00000022150
AA Change: N489K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
34 |
N/A |
INTRINSIC |
|
PTB
|
45 |
179 |
1.16e-27 |
SMART |
|
low complexity region
|
270 |
288 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
306 |
N/A |
INTRINSIC |
|
low complexity region
|
335 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
394 |
N/A |
INTRINSIC |
|
PDB:3H8D|H
|
465 |
493 |
2e-12 |
PDB |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000079689
Gene: ENSMUSG00000022150
AA Change: N707K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
34 |
N/A |
INTRINSIC |
|
PTB
|
45 |
179 |
1.16e-27 |
SMART |
|
low complexity region
|
488 |
506 |
N/A |
INTRINSIC |
|
low complexity region
|
510 |
524 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
612 |
N/A |
INTRINSIC |
|
PDB:3H8D|H
|
683 |
711 |
3e-12 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110663
AA Change: N489K
PolyPhen 2
Score 0.146 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000106291
Gene: ENSMUSG00000022150
AA Change: N489K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
34 |
N/A |
INTRINSIC |
|
PTB
|
45 |
179 |
1.16e-27 |
SMART |
|
low complexity region
|
270 |
288 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
306 |
N/A |
INTRINSIC |
|
low complexity region
|
335 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
394 |
N/A |
INTRINSIC |
|
PDB:3H8D|H
|
465 |
493 |
2e-12 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110664
AA Change: N686K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000106292
Gene: ENSMUSG00000022150
AA Change: N686K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
34 |
N/A |
INTRINSIC |
|
PTB
|
45 |
179 |
1.16e-27 |
SMART |
|
low complexity region
|
467 |
485 |
N/A |
INTRINSIC |
|
low complexity region
|
489 |
503 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
552 |
N/A |
INTRINSIC |
|
low complexity region
|
575 |
591 |
N/A |
INTRINSIC |
|
PDB:3H8D|H
|
662 |
690 |
3e-12 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161812
AA Change: N468K
PolyPhen 2
Score 0.150 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000124589
Gene: ENSMUSG00000022150
AA Change: N468K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
34 |
N/A |
INTRINSIC |
|
PTB
|
45 |
179 |
1.16e-27 |
SMART |
|
low complexity region
|
249 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
334 |
N/A |
INTRINSIC |
|
low complexity region
|
357 |
373 |
N/A |
INTRINSIC |
|
PDB:3H8D|H
|
444 |
472 |
2e-12 |
PDB |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000124996
Gene: ENSMUSG00000022150
AA Change: N574K
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:PTB
|
2 |
59 |
1e-33 |
BLAST |
|
PDB:1P3R|C
|
2 |
59 |
2e-34 |
PDB |
|
SCOP:d1ddma_
|
3 |
59 |
9e-12 |
SMART |
|
low complexity region
|
60 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
356 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
392 |
N/A |
INTRINSIC |
|
low complexity region
|
421 |
441 |
N/A |
INTRINSIC |
|
low complexity region
|
464 |
480 |
N/A |
INTRINSIC |
|
PDB:3H8D|H
|
551 |
579 |
3e-12 |
PDB |
|
| Meta Mutation Damage Score |
0.0859 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (81/82) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Homozygous null mutants exhibit abnormal primitive endoderm structure and/or function, lack a proamniotic cavity and die prior to embryonic day 9.5. A conditional mutant survives, but shows kidney proximal tubule abnormality. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted, knock-out(1) Targeted, other(2) Gene trapped(1) |
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadat |
C |
T |
8: 60,993,158 (GRCm39) |
T373I |
possibly damaging |
Het |
| Abca13 |
T |
C |
11: 9,241,653 (GRCm39) |
L1172P |
possibly damaging |
Het |
| Abcg2 |
A |
G |
6: 58,661,326 (GRCm39) |
Y459C |
probably benign |
Het |
| AC125199.3 |
T |
C |
16: 88,609,061 (GRCm39) |
N4D |
possibly damaging |
Het |
| Acad8 |
A |
G |
9: 26,910,785 (GRCm39) |
M3T |
probably benign |
Het |
| Acsbg3 |
A |
C |
17: 57,189,218 (GRCm39) |
I209L |
probably benign |
Het |
| Adcyap1r1 |
C |
T |
6: 55,474,080 (GRCm39) |
T472I |
probably damaging |
Het |
| Ank3 |
A |
T |
10: 69,840,671 (GRCm39) |
K1890N |
possibly damaging |
Het |
| Asic1 |
G |
A |
15: 99,569,826 (GRCm39) |
C49Y |
probably benign |
Het |
| Atp1a1 |
T |
C |
3: 101,498,547 (GRCm39) |
N215S |
probably damaging |
Het |
| C87436 |
A |
G |
6: 86,422,774 (GRCm39) |
Y116C |
probably damaging |
Het |
| Car5a |
T |
C |
8: 122,671,519 (GRCm39) |
D5G |
probably benign |
Het |
| Ccdc169 |
T |
C |
3: 55,058,368 (GRCm39) |
|
probably null |
Het |
| Ccdc93 |
A |
G |
1: 121,426,970 (GRCm39) |
R586G |
probably damaging |
Het |
| Cep295 |
A |
G |
9: 15,238,007 (GRCm39) |
V131A |
probably damaging |
Het |
| Cox5a |
A |
G |
9: 57,436,329 (GRCm39) |
D60G |
possibly damaging |
Het |
| Cpne6 |
A |
T |
14: 55,750,104 (GRCm39) |
E78D |
probably benign |
Het |
| Cyp2u1 |
T |
C |
3: 131,089,114 (GRCm39) |
E390G |
probably damaging |
Het |
| Dock10 |
A |
T |
1: 80,483,147 (GRCm39) |
D2101E |
probably benign |
Het |
| Duoxa2 |
G |
A |
2: 122,132,357 (GRCm39) |
|
probably null |
Het |
| Eif4a3 |
T |
C |
11: 119,190,758 (GRCm39) |
D22G |
probably benign |
Het |
| Fhip1b |
T |
C |
7: 105,037,477 (GRCm39) |
T369A |
possibly damaging |
Het |
| Fubp3 |
A |
G |
2: 31,482,476 (GRCm39) |
|
probably null |
Het |
| Gm10330 |
A |
G |
12: 23,829,887 (GRCm39) |
L98P |
probably benign |
Het |
| Gm5108 |
A |
G |
5: 68,134,299 (GRCm39) |
*102W |
probably null |
Het |
| Gpr149 |
A |
C |
3: 62,438,478 (GRCm39) |
S560A |
probably damaging |
Het |
| Haspin |
T |
C |
11: 73,027,430 (GRCm39) |
D553G |
probably benign |
Het |
| Hsf1 |
C |
T |
15: 76,382,051 (GRCm39) |
H104Y |
probably benign |
Het |
| Ifi203 |
T |
C |
1: 173,756,494 (GRCm39) |
T430A |
unknown |
Het |
| Itih2 |
G |
A |
2: 10,102,822 (GRCm39) |
Q771* |
probably null |
Het |
| Kazald1 |
T |
A |
19: 45,065,395 (GRCm39) |
L92Q |
probably damaging |
Het |
| Krt19 |
T |
C |
11: 100,031,980 (GRCm39) |
E324G |
probably damaging |
Het |
| Lrrc28 |
A |
T |
7: 67,268,833 (GRCm39) |
V79E |
possibly damaging |
Het |
| Ltn1 |
T |
A |
16: 87,178,381 (GRCm39) |
Q1616L |
probably damaging |
Het |
| Mdc1 |
A |
G |
17: 36,158,843 (GRCm39) |
K408E |
probably benign |
Het |
| Nalcn |
A |
T |
14: 123,561,284 (GRCm39) |
M738K |
probably benign |
Het |
| Ncoa4 |
T |
C |
14: 31,894,848 (GRCm39) |
L125P |
probably damaging |
Het |
| Ncor2 |
G |
T |
5: 125,106,253 (GRCm39) |
R810S |
|
Het |
| Neb |
C |
T |
2: 52,127,141 (GRCm39) |
G348D |
|
Het |
| Nfat5 |
T |
A |
8: 108,095,228 (GRCm39) |
F1156L |
probably damaging |
Het |
| Oit3 |
G |
A |
10: 59,277,468 (GRCm39) |
T13I |
unknown |
Het |
| Opa1 |
A |
C |
16: 29,424,340 (GRCm39) |
Q230P |
probably damaging |
Het |
| Or10j3b |
T |
C |
1: 173,044,064 (GRCm39) |
I282T |
probably damaging |
Het |
| Or52k2 |
T |
A |
7: 102,253,711 (GRCm39) |
I50N |
probably damaging |
Het |
| Or5p66 |
A |
G |
7: 107,886,289 (GRCm39) |
F15L |
probably damaging |
Het |
| Or5w12 |
A |
C |
2: 87,502,567 (GRCm39) |
L48W |
probably damaging |
Het |
| Or6c5b |
G |
T |
10: 129,246,082 (GRCm39) |
M282I |
probably benign |
Het |
| Parpbp |
T |
C |
10: 87,946,189 (GRCm39) |
H410R |
probably null |
Het |
| Pex5l |
A |
G |
3: 33,007,333 (GRCm39) |
V481A |
probably damaging |
Het |
| Plekhh3 |
C |
A |
11: 101,057,225 (GRCm39) |
R344L |
probably benign |
Het |
| Prrc2b |
T |
C |
2: 32,104,953 (GRCm39) |
V1477A |
probably benign |
Het |
| Ptp4a2 |
G |
A |
4: 129,738,945 (GRCm39) |
G94S |
possibly damaging |
Het |
| Ptprk |
T |
A |
10: 28,359,203 (GRCm39) |
Y598* |
probably null |
Het |
| Rfx5 |
C |
A |
3: 94,864,475 (GRCm39) |
T207N |
probably damaging |
Het |
| Rnase2b |
A |
G |
14: 51,400,347 (GRCm39) |
T143A |
possibly damaging |
Het |
| Scn1a |
A |
G |
2: 66,168,330 (GRCm39) |
V92A |
probably benign |
Het |
| Shank2 |
C |
A |
7: 143,965,265 (GRCm39) |
P958T |
probably damaging |
Het |
| Slc13a1 |
A |
G |
6: 24,108,194 (GRCm39) |
I294T |
probably damaging |
Het |
| Slc4a8 |
A |
T |
15: 100,712,421 (GRCm39) |
E1084D |
probably benign |
Het |
| Smurf1 |
T |
A |
5: 144,820,422 (GRCm39) |
R549* |
probably null |
Het |
| Spmip10 |
T |
C |
18: 56,725,537 (GRCm39) |
F66L |
probably damaging |
Het |
| Sprr2b |
T |
C |
3: 92,225,032 (GRCm39) |
C93R |
unknown |
Het |
| Tcn2 |
G |
T |
11: 3,873,569 (GRCm39) |
S259Y |
probably damaging |
Het |
| Tent4a |
G |
T |
13: 69,651,828 (GRCm39) |
T531N |
possibly damaging |
Het |
| Tle1 |
A |
G |
4: 72,076,525 (GRCm39) |
S168P |
possibly damaging |
Het |
| Tnfrsf1b |
C |
T |
4: 144,950,150 (GRCm39) |
G264D |
probably damaging |
Het |
| Tnks2 |
T |
A |
19: 36,823,088 (GRCm39) |
N118K |
probably damaging |
Het |
| Topaz1 |
G |
T |
9: 122,626,930 (GRCm39) |
|
probably benign |
Het |
| Traf3ip1 |
A |
G |
1: 91,443,796 (GRCm39) |
|
probably benign |
Het |
| Ttk |
A |
G |
9: 83,721,322 (GRCm39) |
E69G |
probably damaging |
Het |
| Tulp3 |
T |
C |
6: 128,310,966 (GRCm39) |
D87G |
probably benign |
Het |
| Usp38 |
C |
T |
8: 81,708,479 (GRCm39) |
G1033D |
probably damaging |
Het |
| Usp44 |
T |
A |
10: 93,693,775 (GRCm39) |
N707K |
probably benign |
Het |
| Vipas39 |
T |
A |
12: 87,305,858 (GRCm39) |
R112* |
probably null |
Het |
| Vmn1r185 |
A |
C |
7: 26,311,206 (GRCm39) |
S100A |
probably damaging |
Het |
| Vmn1r209 |
T |
C |
13: 22,990,223 (GRCm39) |
M156V |
probably benign |
Het |
| Vmn1r3 |
G |
A |
4: 3,184,863 (GRCm39) |
T148I |
probably benign |
Het |
| Wdr41 |
G |
A |
13: 95,151,620 (GRCm39) |
R260H |
probably benign |
Het |
| Wdr90 |
G |
A |
17: 26,076,146 (GRCm39) |
R104C |
|
Het |
| Wnk2 |
A |
T |
13: 49,221,711 (GRCm39) |
H1183Q |
possibly damaging |
Het |
| Zfp667 |
A |
T |
7: 6,308,256 (GRCm39) |
H308L |
possibly damaging |
Het |
| Zfp952 |
A |
G |
17: 33,220,628 (GRCm39) |
N18D |
possibly damaging |
Het |
|
| Other mutations in Dab2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00586:Dab2
|
APN |
15 |
6,459,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00731:Dab2
|
APN |
15 |
6,465,191 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02382:Dab2
|
APN |
15 |
6,466,468 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL02598:Dab2
|
APN |
15 |
6,458,847 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03054:Dab2
|
APN |
15 |
6,447,707 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03093:Dab2
|
APN |
15 |
6,465,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03369:Dab2
|
APN |
15 |
6,464,790 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL03372:Dab2
|
APN |
15 |
6,459,030 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0157:Dab2
|
UTSW |
15 |
6,459,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0326:Dab2
|
UTSW |
15 |
6,447,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0488:Dab2
|
UTSW |
15 |
6,454,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0552:Dab2
|
UTSW |
15 |
6,464,895 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0938:Dab2
|
UTSW |
15 |
6,464,865 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1433:Dab2
|
UTSW |
15 |
6,459,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Dab2
|
UTSW |
15 |
6,459,351 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1713:Dab2
|
UTSW |
15 |
6,459,182 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1757:Dab2
|
UTSW |
15 |
6,359,933 (GRCm39) |
intron |
probably benign |
|
|
R1800:Dab2
|
UTSW |
15 |
6,464,948 (GRCm39) |
missense |
probably benign |
|
|
R1837:Dab2
|
UTSW |
15 |
6,365,957 (GRCm39) |
intron |
probably benign |
|
|
R1999:Dab2
|
UTSW |
15 |
6,446,398 (GRCm39) |
missense |
probably benign |
0.32 |
|
R2050:Dab2
|
UTSW |
15 |
6,464,696 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2117:Dab2
|
UTSW |
15 |
6,465,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2129:Dab2
|
UTSW |
15 |
6,365,864 (GRCm39) |
nonsense |
probably null |
|
|
R2150:Dab2
|
UTSW |
15 |
6,446,398 (GRCm39) |
missense |
probably benign |
0.32 |
|
R2329:Dab2
|
UTSW |
15 |
6,459,044 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2338:Dab2
|
UTSW |
15 |
6,464,733 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2680:Dab2
|
UTSW |
15 |
6,466,474 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3978:Dab2
|
UTSW |
15 |
6,464,644 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3979:Dab2
|
UTSW |
15 |
6,464,644 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3980:Dab2
|
UTSW |
15 |
6,464,644 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4551:Dab2
|
UTSW |
15 |
6,464,775 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4795:Dab2
|
UTSW |
15 |
6,459,092 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4829:Dab2
|
UTSW |
15 |
6,454,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4830:Dab2
|
UTSW |
15 |
6,457,008 (GRCm39) |
missense |
probably benign |
|
|
R4832:Dab2
|
UTSW |
15 |
6,366,080 (GRCm39) |
splice site |
probably null |
|
|
R5168:Dab2
|
UTSW |
15 |
6,365,924 (GRCm39) |
intron |
probably benign |
|
|
R5620:Dab2
|
UTSW |
15 |
6,447,796 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5996:Dab2
|
UTSW |
15 |
6,464,792 (GRCm39) |
nonsense |
probably null |
|
|
R6159:Dab2
|
UTSW |
15 |
6,465,941 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6998:Dab2
|
UTSW |
15 |
6,454,130 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7002:Dab2
|
UTSW |
15 |
6,464,846 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7040:Dab2
|
UTSW |
15 |
6,451,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7138:Dab2
|
UTSW |
15 |
6,458,780 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7448:Dab2
|
UTSW |
15 |
6,451,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7548:Dab2
|
UTSW |
15 |
6,459,399 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8062:Dab2
|
UTSW |
15 |
6,456,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8124:Dab2
|
UTSW |
15 |
6,458,878 (GRCm39) |
nonsense |
probably null |
|
|
R8164:Dab2
|
UTSW |
15 |
6,460,449 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8171:Dab2
|
UTSW |
15 |
6,453,407 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8230:Dab2
|
UTSW |
15 |
6,451,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8372:Dab2
|
UTSW |
15 |
6,446,406 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8427:Dab2
|
UTSW |
15 |
6,458,840 (GRCm39) |
nonsense |
probably null |
|
|
R9363:Dab2
|
UTSW |
15 |
6,460,481 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9461:Dab2
|
UTSW |
15 |
6,460,435 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9532:Dab2
|
UTSW |
15 |
6,451,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9779:Dab2
|
UTSW |
15 |
6,460,525 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CGCTTTCACTGGCTTAGACC -3'
(R):5'- ATTGGCTGAGGTAAAGGGCTC -3'
Sequencing Primer
(F):5'- ACTGGCTTAGACCCCCTTGG -3'
(R):5'- CTAAGGTGAATGGTTAAGTGACCTCC -3'
|
| Posted On |
2021-08-02 |
Incidental Mutation