Incidental Mutation 'R8679:Iars1'
| ID |
679779 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iars1
|
| Ensembl Gene |
ENSMUSG00000037851 |
| Gene Name |
isoleucyl-tRNA synthetase 1 |
| Synonyms |
Iars, 2510016L12Rik, E430001P04Rik |
| MMRRC Submission |
068534-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8679 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
49835606-49887743 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
C to A
at 49856675 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130204
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047363]
[ENSMUST00000164260]
[ENSMUST00000165316]
[ENSMUST00000171510]
|
| AlphaFold |
Q8BU30 |
| Predicted Effect |
silent
Transcript: ENSMUST00000047363
|
| SMART Domains |
Protein: ENSMUSP00000048096
Gene: ENSMUSG00000037851
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA-synt_1
|
17 |
639 |
9.2e-242 |
PFAM |
|
Pfam:tRNA-synt_1g
|
46 |
197 |
3.7e-6 |
PFAM |
|
Pfam:Anticodon_1
|
693 |
852 |
1.1e-23 |
PFAM |
|
low complexity region
|
1159 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1169 |
1180 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1229 |
N/A |
INTRINSIC |
|
| Predicted Effect |
silent
Transcript: ENSMUST00000164260
|
| SMART Domains |
Protein: ENSMUSP00000126806
Gene: ENSMUSG00000037851
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA-synt_1
|
17 |
639 |
5.5e-238 |
PFAM |
|
Pfam:tRNA-synt_1g
|
46 |
205 |
5.2e-8 |
PFAM |
|
Pfam:tRNA-synt_1g
|
521 |
659 |
2.1e-5 |
PFAM |
|
Pfam:Anticodon_1
|
693 |
852 |
7.1e-24 |
PFAM |
|
low complexity region
|
1159 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1169 |
1180 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1229 |
N/A |
INTRINSIC |
|
| Predicted Effect |
silent
Transcript: ENSMUST00000165316
|
| SMART Domains |
Protein: ENSMUSP00000132082
Gene: ENSMUSG00000037851
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA-synt_1
|
17 |
639 |
5.5e-238 |
PFAM |
|
Pfam:tRNA-synt_1g
|
46 |
205 |
5.2e-8 |
PFAM |
|
Pfam:tRNA-synt_1g
|
521 |
659 |
2.1e-5 |
PFAM |
|
Pfam:Anticodon_1
|
693 |
852 |
7.1e-24 |
PFAM |
|
low complexity region
|
1159 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1169 |
1180 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1229 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171510
|
| SMART Domains |
Protein: ENSMUSP00000130204
Gene: ENSMUSG00000037851
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA-synt_1
|
1 |
96 |
5.6e-28 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.4%
|
| Validation Efficiency |
98% (91/93) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc5 |
T |
C |
16: 20,152,479 (GRCm39) |
T1356A |
possibly damaging |
Het |
| Ace3 |
A |
G |
11: 105,886,701 (GRCm39) |
T154A |
probably benign |
Het |
| Arhgap31 |
C |
A |
16: 38,422,966 (GRCm39) |
Q1033H |
probably damaging |
Het |
| C1qtnf1 |
C |
T |
11: 118,337,340 (GRCm39) |
R57* |
probably null |
Het |
| Cacna1g |
T |
C |
11: 94,319,962 (GRCm39) |
T1405A |
probably damaging |
Het |
| Cacna1i |
A |
G |
15: 80,260,011 (GRCm39) |
|
probably benign |
Het |
| Cdca4 |
T |
A |
12: 112,785,734 (GRCm39) |
|
probably null |
Het |
| Cpa4 |
T |
A |
6: 30,585,158 (GRCm39) |
M314K |
probably damaging |
Het |
| Cpn2 |
A |
T |
16: 30,078,085 (GRCm39) |
S539T |
possibly damaging |
Het |
| Crebbp |
A |
G |
16: 3,902,322 (GRCm39) |
S2306P |
probably damaging |
Het |
| Cspg4b |
A |
G |
13: 113,488,163 (GRCm39) |
R9G |
|
Het |
| Dcaf5 |
T |
C |
12: 80,385,807 (GRCm39) |
H773R |
probably benign |
Het |
| Dcun1d2 |
A |
T |
8: 13,311,406 (GRCm39) |
D194E |
probably benign |
Het |
| Dnah1 |
G |
T |
14: 30,989,767 (GRCm39) |
R3250S |
possibly damaging |
Het |
| Dnajc25 |
A |
C |
4: 59,020,195 (GRCm39) |
K206T |
possibly damaging |
Het |
| Dnajc27 |
T |
C |
12: 4,146,325 (GRCm39) |
L118P |
possibly damaging |
Het |
| Etl4 |
C |
T |
2: 20,714,288 (GRCm39) |
T129I |
probably damaging |
Het |
| Faap100 |
A |
G |
11: 120,263,003 (GRCm39) |
I785T |
probably damaging |
Het |
| Fam227b |
A |
T |
2: 125,830,928 (GRCm39) |
D425E |
probably benign |
Het |
| Fat4 |
C |
G |
3: 39,064,842 (GRCm39) |
L4933V |
probably damaging |
Het |
| Fbrsl1 |
A |
G |
5: 110,526,086 (GRCm39) |
F39L |
probably damaging |
Het |
| Fezf1 |
A |
G |
6: 23,247,769 (GRCm39) |
V102A |
probably benign |
Het |
| Gabra2 |
T |
C |
5: 71,170,040 (GRCm39) |
|
probably benign |
Het |
| Garnl3 |
C |
A |
2: 32,916,106 (GRCm39) |
R346L |
probably damaging |
Het |
| Grin2a |
A |
T |
16: 9,403,089 (GRCm39) |
I799N |
possibly damaging |
Het |
| Hspa4 |
A |
G |
11: 53,160,691 (GRCm39) |
F462L |
probably damaging |
Het |
| Igkv6-32 |
C |
T |
6: 70,051,063 (GRCm39) |
V98M |
possibly damaging |
Het |
| Il31ra |
A |
G |
13: 112,662,372 (GRCm39) |
F560S |
possibly damaging |
Het |
| Itpr3 |
G |
A |
17: 27,337,651 (GRCm39) |
|
probably benign |
Het |
| Kif2a |
G |
A |
13: 107,116,049 (GRCm39) |
T299I |
probably damaging |
Het |
| Leo1 |
T |
A |
9: 75,373,544 (GRCm39) |
Y656* |
probably null |
Het |
| Lpcat2 |
T |
A |
8: 93,635,864 (GRCm39) |
V422D |
probably damaging |
Het |
| Lrrcc1 |
T |
A |
3: 14,601,084 (GRCm39) |
S39T |
probably benign |
Het |
| Macf1 |
A |
T |
4: 123,405,869 (GRCm39) |
S341T |
probably benign |
Het |
| Mc2r |
T |
A |
18: 68,540,879 (GRCm39) |
Y138F |
probably damaging |
Het |
| Mepe |
A |
G |
5: 104,485,754 (GRCm39) |
N298S |
possibly damaging |
Het |
| Mmp15 |
C |
A |
8: 96,092,982 (GRCm39) |
N120K |
possibly damaging |
Het |
| Mrps9 |
A |
G |
1: 42,918,915 (GRCm39) |
R106G |
probably damaging |
Het |
| Muc16 |
T |
A |
9: 18,557,744 (GRCm39) |
M2850L |
unknown |
Het |
| Mxra8 |
T |
A |
4: 155,927,122 (GRCm39) |
I352N |
probably damaging |
Het |
| Myo16 |
G |
A |
8: 10,411,042 (GRCm39) |
V167I |
unknown |
Het |
| Neb |
T |
C |
2: 52,215,051 (GRCm39) |
D209G |
probably damaging |
Het |
| Nlgn2 |
A |
G |
11: 69,716,309 (GRCm39) |
V744A |
probably benign |
Het |
| Notch2 |
A |
G |
3: 98,029,218 (GRCm39) |
|
probably null |
Het |
| Nr1d1 |
G |
C |
11: 98,660,073 (GRCm39) |
R484G |
probably damaging |
Het |
| Or14c42-ps1 |
A |
T |
7: 86,211,147 (GRCm39) |
H69L |
unknown |
Het |
| Or5ak20 |
T |
C |
2: 85,183,953 (GRCm39) |
T106A |
probably benign |
Het |
| Or5k16 |
G |
A |
16: 58,736,843 (GRCm39) |
R54C |
probably benign |
Het |
| Or9k2b |
T |
C |
10: 130,016,702 (GRCm39) |
I16V |
probably benign |
Het |
| Oxa1l |
A |
G |
14: 54,605,248 (GRCm39) |
|
probably null |
Het |
| Piwil4 |
T |
C |
9: 14,616,322 (GRCm39) |
D15G |
|
Het |
| Plcz1 |
C |
A |
6: 139,949,612 (GRCm39) |
W461L |
probably damaging |
Het |
| Plek |
A |
T |
11: 16,944,676 (GRCm39) |
I118N |
probably damaging |
Het |
| Poc1b |
C |
A |
10: 99,000,728 (GRCm39) |
|
probably benign |
Het |
| Potefam1 |
A |
T |
2: 111,059,567 (GRCm39) |
M64K |
possibly damaging |
Het |
| Ppp1r16b |
G |
A |
2: 158,593,098 (GRCm39) |
D226N |
probably damaging |
Het |
| Prss36 |
T |
C |
7: 127,532,635 (GRCm39) |
T739A |
possibly damaging |
Het |
| Psme2 |
A |
T |
14: 55,827,074 (GRCm39) |
|
probably null |
Het |
| Ptprb |
T |
G |
10: 116,203,495 (GRCm39) |
V1802G |
probably damaging |
Het |
| Rabep2 |
C |
A |
7: 126,034,848 (GRCm39) |
Y84* |
probably null |
Het |
| Rbbp6 |
T |
G |
7: 122,600,516 (GRCm39) |
S1508A |
unknown |
Het |
| Rel |
A |
T |
11: 23,692,430 (GRCm39) |
D534E |
probably benign |
Het |
| Rpgrip1 |
G |
A |
14: 52,396,852 (GRCm39) |
S1258N |
probably damaging |
Het |
| Rprml |
T |
C |
11: 103,540,953 (GRCm39) |
L116P |
probably damaging |
Het |
| Rsph10b |
A |
G |
5: 143,887,112 (GRCm39) |
T323A |
possibly damaging |
Het |
| Rtn4rl1 |
A |
G |
11: 75,156,099 (GRCm39) |
H177R |
probably damaging |
Het |
| Sag |
A |
G |
1: 87,738,032 (GRCm39) |
T24A |
probably benign |
Het |
| Scgb2b26 |
G |
T |
7: 33,643,784 (GRCm39) |
T52N |
probably damaging |
Het |
| Scn10a |
T |
C |
9: 119,501,194 (GRCm39) |
I197V |
probably damaging |
Het |
| Sec24c |
T |
A |
14: 20,742,927 (GRCm39) |
V1003D |
possibly damaging |
Het |
| Sirt2 |
G |
A |
7: 28,471,261 (GRCm39) |
G30E |
probably damaging |
Het |
| Slc13a5 |
T |
A |
11: 72,149,919 (GRCm39) |
Q197L |
probably benign |
Het |
| Slc44a3 |
A |
T |
3: 121,283,918 (GRCm39) |
S445T |
probably damaging |
Het |
| Slc7a7 |
A |
T |
14: 54,610,449 (GRCm39) |
V399E |
probably benign |
Het |
| Smarcad1 |
T |
A |
6: 65,088,865 (GRCm39) |
D1000E |
probably benign |
Het |
| Sorcs2 |
G |
T |
5: 36,196,657 (GRCm39) |
Q663K |
probably benign |
Het |
| Stat4 |
A |
G |
1: 52,118,991 (GRCm39) |
R345G |
probably null |
Het |
| Sycp2 |
G |
A |
2: 177,992,768 (GRCm39) |
R1261C |
probably damaging |
Het |
| Tcf19 |
T |
C |
17: 35,825,381 (GRCm39) |
I259V |
probably benign |
Het |
| Thada |
T |
A |
17: 84,536,637 (GRCm39) |
R1636S |
probably benign |
Het |
| Tnrc6c |
T |
C |
11: 117,604,961 (GRCm39) |
L32P |
probably benign |
Het |
| Tonsl |
G |
A |
15: 76,517,076 (GRCm39) |
T881I |
probably benign |
Het |
| Tonsl |
A |
C |
15: 76,518,263 (GRCm39) |
C570G |
probably damaging |
Het |
| Ube2o |
C |
A |
11: 116,432,273 (GRCm39) |
E898* |
probably null |
Het |
| Usp5 |
T |
C |
6: 124,794,394 (GRCm39) |
H762R |
possibly damaging |
Het |
| Vmn2r15 |
A |
G |
5: 109,434,779 (GRCm39) |
S642P |
probably benign |
Het |
| Vmn2r23 |
T |
C |
6: 123,690,431 (GRCm39) |
W436R |
probably damaging |
Het |
| Vps13d |
A |
C |
4: 144,811,977 (GRCm39) |
I3343M |
|
Het |
| Wbp11 |
T |
C |
6: 136,799,932 (GRCm39) |
K83E |
probably damaging |
Het |
| Zfp26 |
T |
A |
9: 20,356,201 (GRCm39) |
N36Y |
possibly damaging |
Het |
| Zfp57 |
T |
A |
17: 37,320,938 (GRCm39) |
I264N |
probably damaging |
Het |
|
| Other mutations in Iars1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00697:Iars1
|
APN |
13 |
49,863,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00764:Iars1
|
APN |
13 |
49,865,303 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL01153:Iars1
|
APN |
13 |
49,865,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01481:Iars1
|
APN |
13 |
49,882,174 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01596:Iars1
|
APN |
13 |
49,856,652 (GRCm39) |
missense |
probably benign |
|
|
IGL01682:Iars1
|
APN |
13 |
49,863,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01885:Iars1
|
APN |
13 |
49,844,975 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL01907:Iars1
|
APN |
13 |
49,863,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02023:Iars1
|
APN |
13 |
49,841,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02121:Iars1
|
APN |
13 |
49,878,172 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02365:Iars1
|
APN |
13 |
49,844,975 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02704:Iars1
|
APN |
13 |
49,874,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02838:Iars1
|
APN |
13 |
49,843,965 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02975:Iars1
|
APN |
13 |
49,858,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02982:Iars1
|
APN |
13 |
49,863,185 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03034:Iars1
|
APN |
13 |
49,843,965 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03060:Iars1
|
APN |
13 |
49,843,923 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03156:Iars1
|
APN |
13 |
49,856,655 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03206:Iars1
|
APN |
13 |
49,846,546 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03343:Iars1
|
APN |
13 |
49,878,223 (GRCm39) |
missense |
probably benign |
0.12 |
|
gannett_peak
|
UTSW |
13 |
49,861,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
missouri
|
UTSW |
13 |
49,841,752 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
spacex
|
UTSW |
13 |
49,876,478 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
wind_river
|
UTSW |
13 |
49,855,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Iars1
|
UTSW |
13 |
49,846,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Iars1
|
UTSW |
13 |
49,846,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0184:Iars1
|
UTSW |
13 |
49,875,688 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0200:Iars1
|
UTSW |
13 |
49,879,678 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R0356:Iars1
|
UTSW |
13 |
49,856,709 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0383:Iars1
|
UTSW |
13 |
49,885,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0657:Iars1
|
UTSW |
13 |
49,855,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1005:Iars1
|
UTSW |
13 |
49,840,921 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1427:Iars1
|
UTSW |
13 |
49,857,745 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1449:Iars1
|
UTSW |
13 |
49,887,186 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1647:Iars1
|
UTSW |
13 |
49,876,478 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1648:Iars1
|
UTSW |
13 |
49,876,478 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1664:Iars1
|
UTSW |
13 |
49,865,251 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1763:Iars1
|
UTSW |
13 |
49,876,553 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2192:Iars1
|
UTSW |
13 |
49,841,605 (GRCm39) |
splice site |
probably null |
|
|
R2203:Iars1
|
UTSW |
13 |
49,876,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2357:Iars1
|
UTSW |
13 |
49,841,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3724:Iars1
|
UTSW |
13 |
49,840,860 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4785:Iars1
|
UTSW |
13 |
49,878,139 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4934:Iars1
|
UTSW |
13 |
49,871,460 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4999:Iars1
|
UTSW |
13 |
49,863,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5048:Iars1
|
UTSW |
13 |
49,841,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5268:Iars1
|
UTSW |
13 |
49,843,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Iars1
|
UTSW |
13 |
49,875,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5486:Iars1
|
UTSW |
13 |
49,863,049 (GRCm39) |
splice site |
probably null |
|
|
R5960:Iars1
|
UTSW |
13 |
49,878,113 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5972:Iars1
|
UTSW |
13 |
49,863,108 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5978:Iars1
|
UTSW |
13 |
49,876,469 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6031:Iars1
|
UTSW |
13 |
49,859,307 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6031:Iars1
|
UTSW |
13 |
49,859,307 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6092:Iars1
|
UTSW |
13 |
49,861,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6167:Iars1
|
UTSW |
13 |
49,876,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Iars1
|
UTSW |
13 |
49,861,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6358:Iars1
|
UTSW |
13 |
49,880,619 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R6385:Iars1
|
UTSW |
13 |
49,855,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6403:Iars1
|
UTSW |
13 |
49,840,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6575:Iars1
|
UTSW |
13 |
49,878,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6675:Iars1
|
UTSW |
13 |
49,873,054 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6957:Iars1
|
UTSW |
13 |
49,875,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7207:Iars1
|
UTSW |
13 |
49,841,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7254:Iars1
|
UTSW |
13 |
49,876,554 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7354:Iars1
|
UTSW |
13 |
49,857,796 (GRCm39) |
missense |
probably benign |
|
|
R7397:Iars1
|
UTSW |
13 |
49,882,153 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7696:Iars1
|
UTSW |
13 |
49,860,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7799:Iars1
|
UTSW |
13 |
49,876,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7828:Iars1
|
UTSW |
13 |
49,878,748 (GRCm39) |
missense |
probably benign |
|
|
R8768:Iars1
|
UTSW |
13 |
49,878,102 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8797:Iars1
|
UTSW |
13 |
49,841,738 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8906:Iars1
|
UTSW |
13 |
49,882,177 (GRCm39) |
missense |
probably benign |
|
|
R8990:Iars1
|
UTSW |
13 |
49,841,752 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9134:Iars1
|
UTSW |
13 |
49,855,323 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9137:Iars1
|
UTSW |
13 |
49,855,350 (GRCm39) |
missense |
probably benign |
|
|
R9394:Iars1
|
UTSW |
13 |
49,883,536 (GRCm39) |
missense |
probably benign |
|
|
R9668:Iars1
|
UTSW |
13 |
49,840,885 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9741:Iars1
|
UTSW |
13 |
49,844,978 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Iars1
|
UTSW |
13 |
49,874,564 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACATGTGGGTGTGTCTACAG -3'
(R):5'- TTCCATTGGTCTTGGCAAGGC -3'
Sequencing Primer
(F):5'- TGTCTACAGGTGTGCACAC -3'
(R):5'- CAAAGAAGTTTAATGAGAGTCGTGAC -3'
|
| Posted On |
2021-08-11 |
Incidental Mutation