Incidental Mutation 'R8905:Robo1'
| ID |
680058 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Robo1
|
| Ensembl Gene |
ENSMUSG00000022883 |
| Gene Name |
roundabout guidance receptor 1 |
| Synonyms |
DUTT1 |
| MMRRC Submission |
068762-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8905 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
72105194-72842983 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 72539173 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 90
(D90V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156106
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023600]
[ENSMUST00000231580]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000023600
AA Change: D72V
PolyPhen 2
Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000023600
Gene: ENSMUSG00000022883
AA Change: D72V
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
41 |
115 |
3.15e-10 |
SMART |
|
IGc2
|
143 |
208 |
2.52e-9 |
SMART |
|
IGc2
|
235 |
298 |
3.85e-14 |
SMART |
|
IGv
|
328 |
391 |
3.71e-7 |
SMART |
|
IGc2
|
428 |
493 |
2.46e-12 |
SMART |
|
FN3
|
522 |
604 |
3.17e-13 |
SMART |
|
FN3
|
634 |
721 |
1.66e0 |
SMART |
|
FN3
|
736 |
822 |
4.28e-10 |
SMART |
|
low complexity region
|
1108 |
1125 |
N/A |
INTRINSIC |
|
low complexity region
|
1148 |
1157 |
N/A |
INTRINSIC |
|
low complexity region
|
1186 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1282 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1345 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1380 |
N/A |
INTRINSIC |
|
low complexity region
|
1442 |
1449 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1576 |
N/A |
INTRINSIC |
|
low complexity region
|
1602 |
1611 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000231580
AA Change: D90V
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.3%
|
| Validation Efficiency |
100% (77/77) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
PHENOTYPE: Mice homozygous for a reporter allele show altered axon guidance. Mice homozygous for a null allele die at birth showing aberrant axon pathfinding and cortical interneuron migration. Homozygotes for another null allele show neonatal death, aphagia, delayed lung maturation and bronchial hyperplasia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700013G24Rik |
T |
C |
4: 137,182,553 (GRCm39) |
V236A |
probably benign |
Het |
| Abca15 |
A |
T |
7: 119,960,771 (GRCm39) |
R744S |
probably benign |
Het |
| Adgra1 |
T |
C |
7: 139,455,763 (GRCm39) |
S464P |
probably damaging |
Het |
| Arhgap45 |
T |
C |
10: 79,855,570 (GRCm39) |
V3A |
probably benign |
Het |
| AW554918 |
T |
A |
18: 25,473,206 (GRCm39) |
S134T |
probably damaging |
Het |
| Bmper |
A |
G |
9: 23,318,082 (GRCm39) |
E567G |
probably benign |
Het |
| C2cd3 |
T |
C |
7: 100,074,132 (GRCm39) |
|
probably null |
Het |
| Cars1 |
A |
G |
7: 143,140,196 (GRCm39) |
Y170H |
probably damaging |
Het |
| Celsr1 |
A |
T |
15: 85,788,269 (GRCm39) |
|
probably benign |
Het |
| Celsr3 |
C |
T |
9: 108,718,501 (GRCm39) |
H2351Y |
probably damaging |
Het |
| Cfap210 |
A |
G |
2: 69,612,104 (GRCm39) |
S175P |
probably benign |
Het |
| Clxn |
A |
G |
16: 14,738,275 (GRCm39) |
I147V |
possibly damaging |
Het |
| Cyp2d11 |
T |
C |
15: 82,275,102 (GRCm39) |
I282V |
probably benign |
Het |
| Dhfr |
A |
G |
13: 92,494,467 (GRCm39) |
T57A |
probably damaging |
Het |
| Dhrs7l |
T |
A |
12: 72,666,431 (GRCm39) |
D80V |
probably damaging |
Het |
| Dnah7b |
A |
C |
1: 46,292,534 (GRCm39) |
Q2973P |
probably damaging |
Het |
| Dnajc5b |
T |
C |
3: 19,633,184 (GRCm39) |
C136R |
probably benign |
Het |
| Ercc3 |
T |
G |
18: 32,398,771 (GRCm39) |
D683E |
possibly damaging |
Het |
| Faxc |
A |
G |
4: 21,982,398 (GRCm39) |
Y279C |
probably damaging |
Het |
| Fbxw7 |
T |
C |
3: 84,872,634 (GRCm39) |
M191T |
possibly damaging |
Het |
| Fcgbp |
T |
A |
7: 27,785,934 (GRCm39) |
V457E |
probably damaging |
Het |
| Fip1l1 |
A |
T |
5: 74,756,624 (GRCm39) |
T539S |
probably damaging |
Het |
| Gabra1 |
T |
C |
11: 42,038,052 (GRCm39) |
T189A |
possibly damaging |
Het |
| Glg1 |
T |
C |
8: 111,884,668 (GRCm39) |
D1118G |
probably damaging |
Het |
| Gli3 |
A |
G |
13: 15,901,116 (GRCm39) |
D1501G |
probably benign |
Het |
| Hacd1 |
A |
G |
2: 14,049,761 (GRCm39) |
I91T |
possibly damaging |
Het |
| Ift22 |
T |
C |
5: 136,941,745 (GRCm39) |
V159A |
probably benign |
Het |
| Igkv1-110 |
T |
A |
6: 68,248,070 (GRCm39) |
Y60N |
probably damaging |
Het |
| Inpp5d |
A |
G |
1: 87,637,348 (GRCm39) |
K502E |
probably damaging |
Het |
| Kcnt2 |
A |
T |
1: 140,435,467 (GRCm39) |
Q478L |
possibly damaging |
Het |
| Mettl13 |
A |
G |
1: 162,364,847 (GRCm39) |
F511L |
probably damaging |
Het |
| Mis18bp1 |
T |
C |
12: 65,180,401 (GRCm39) |
|
probably null |
Het |
| Mrps30 |
A |
T |
13: 118,523,479 (GRCm39) |
S98T |
probably benign |
Het |
| Muc2 |
C |
T |
7: 141,279,643 (GRCm39) |
A209V |
probably benign |
Het |
| Nfs1 |
A |
T |
2: 155,970,503 (GRCm39) |
I270N |
probably damaging |
Het |
| Nlgn3 |
T |
C |
X: 100,352,390 (GRCm39) |
V179A |
probably damaging |
Het |
| Nsmaf |
A |
G |
4: 6,424,951 (GRCm39) |
S266P |
probably benign |
Het |
| Obscn |
A |
G |
11: 58,960,784 (GRCm39) |
S3176P |
probably damaging |
Het |
| Or4c123 |
A |
T |
2: 89,126,801 (GRCm39) |
L271Q |
possibly damaging |
Het |
| Or7g12 |
A |
G |
9: 18,899,494 (GRCm39) |
D70G |
possibly damaging |
Het |
| P2ry12 |
T |
A |
3: 59,124,997 (GRCm39) |
Y226F |
probably damaging |
Het |
| Pabpc2 |
C |
A |
18: 39,907,704 (GRCm39) |
T323K |
probably benign |
Het |
| Pank2 |
A |
G |
2: 131,124,646 (GRCm39) |
D71G |
possibly damaging |
Het |
| Patj |
A |
T |
4: 98,385,412 (GRCm39) |
H393L |
probably damaging |
Het |
| Pde8b |
A |
G |
13: 95,182,993 (GRCm39) |
V255A |
probably damaging |
Het |
| Plekhs1 |
T |
C |
19: 56,471,028 (GRCm39) |
W374R |
probably damaging |
Het |
| Ppm1g |
T |
C |
5: 31,361,437 (GRCm39) |
D313G |
probably damaging |
Het |
| Rnf114 |
A |
G |
2: 167,353,134 (GRCm39) |
N135S |
probably benign |
Het |
| Rnf43 |
T |
G |
11: 87,621,951 (GRCm39) |
Y351D |
probably damaging |
Het |
| Sbds |
A |
G |
5: 130,277,125 (GRCm39) |
V172A |
possibly damaging |
Het |
| Scamp5 |
T |
A |
9: 57,352,669 (GRCm39) |
I167F |
probably benign |
Het |
| Sec14l5 |
A |
G |
16: 4,994,364 (GRCm39) |
E386G |
probably damaging |
Het |
| Sfxn1 |
T |
A |
13: 54,246,433 (GRCm39) |
V159E |
probably damaging |
Het |
| Sgsm1 |
C |
T |
5: 113,421,495 (GRCm39) |
G531R |
probably benign |
Het |
| Slc22a26 |
T |
A |
19: 7,760,331 (GRCm39) |
I471F |
probably damaging |
Het |
| Slc41a3 |
T |
A |
6: 90,589,123 (GRCm39) |
M78K |
probably benign |
Het |
| Slc8a1 |
A |
T |
17: 81,749,084 (GRCm39) |
Y653N |
probably benign |
Het |
| Slco6c1 |
A |
T |
1: 97,053,391 (GRCm39) |
M170K |
possibly damaging |
Het |
| Smarca5 |
A |
T |
8: 81,440,577 (GRCm39) |
I629K |
probably benign |
Het |
| Smg7 |
T |
A |
1: 152,715,817 (GRCm39) |
D1099V |
probably damaging |
Het |
| Spata31e2 |
A |
G |
1: 26,721,895 (GRCm39) |
V1095A |
probably damaging |
Het |
| Srbd1 |
T |
C |
17: 86,308,890 (GRCm39) |
I763V |
probably benign |
Het |
| Stk25 |
A |
G |
1: 93,556,929 (GRCm39) |
S30P |
probably damaging |
Het |
| Sv2b |
C |
T |
7: 74,767,459 (GRCm39) |
A646T |
probably benign |
Het |
| Tardbp |
T |
C |
4: 148,705,093 (GRCm39) |
M167V |
probably benign |
Het |
| Tmem132a |
T |
C |
19: 10,842,647 (GRCm39) |
N276S |
probably damaging |
Het |
| Ttpa |
T |
A |
4: 20,028,435 (GRCm39) |
S162T |
probably benign |
Het |
| Usp13 |
T |
C |
3: 32,935,572 (GRCm39) |
Y333H |
probably damaging |
Het |
| Vmn2r3 |
T |
A |
3: 64,166,695 (GRCm39) |
Y812F |
probably damaging |
Het |
| Yeats2 |
A |
G |
16: 20,009,144 (GRCm39) |
T463A |
probably benign |
Het |
| Zbtb26 |
T |
A |
2: 37,326,927 (GRCm39) |
K36N |
probably benign |
Het |
| Zfc3h1 |
A |
T |
10: 115,259,383 (GRCm39) |
T1652S |
probably benign |
Het |
| Zfp472 |
G |
A |
17: 33,197,455 (GRCm39) |
C510Y |
possibly damaging |
Het |
| Zfp518a |
C |
A |
19: 40,902,780 (GRCm39) |
T903K |
probably damaging |
Het |
| Zfp668 |
T |
C |
7: 127,465,598 (GRCm39) |
T529A |
probably benign |
Het |
| Zfp930 |
A |
G |
8: 69,681,351 (GRCm39) |
T349A |
possibly damaging |
Het |
| Zmiz2 |
T |
G |
11: 6,346,840 (GRCm39) |
Y182D |
probably damaging |
Het |
|
| Other mutations in Robo1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01766:Robo1
|
APN |
16 |
72,801,553 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01937:Robo1
|
APN |
16 |
72,759,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01945:Robo1
|
APN |
16 |
72,759,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02151:Robo1
|
APN |
16 |
72,786,504 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02232:Robo1
|
APN |
16 |
72,768,872 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02282:Robo1
|
APN |
16 |
72,539,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02590:Robo1
|
APN |
16 |
72,840,020 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02874:Robo1
|
APN |
16 |
72,809,806 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02974:Robo1
|
APN |
16 |
72,803,750 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03233:Robo1
|
APN |
16 |
72,767,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4378001:Robo1
|
UTSW |
16 |
72,801,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0079:Robo1
|
UTSW |
16 |
72,730,230 (GRCm39) |
splice site |
probably benign |
|
|
R0254:Robo1
|
UTSW |
16 |
72,461,058 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0366:Robo1
|
UTSW |
16 |
72,539,133 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R0410:Robo1
|
UTSW |
16 |
72,768,872 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0511:Robo1
|
UTSW |
16 |
72,810,013 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0563:Robo1
|
UTSW |
16 |
72,769,174 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0637:Robo1
|
UTSW |
16 |
72,798,839 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1239:Robo1
|
UTSW |
16 |
72,821,430 (GRCm39) |
splice site |
probably null |
|
|
R1773:Robo1
|
UTSW |
16 |
72,801,399 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1777:Robo1
|
UTSW |
16 |
72,801,555 (GRCm39) |
missense |
probably benign |
|
|
R1901:Robo1
|
UTSW |
16 |
72,757,092 (GRCm39) |
missense |
probably null |
1.00 |
|
R1902:Robo1
|
UTSW |
16 |
72,757,092 (GRCm39) |
missense |
probably null |
1.00 |
|
R1903:Robo1
|
UTSW |
16 |
72,757,092 (GRCm39) |
missense |
probably null |
1.00 |
|
R1996:Robo1
|
UTSW |
16 |
72,767,067 (GRCm39) |
missense |
probably benign |
0.40 |
|
R2040:Robo1
|
UTSW |
16 |
72,730,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Robo1
|
UTSW |
16 |
72,775,660 (GRCm39) |
missense |
probably benign |
|
|
R2269:Robo1
|
UTSW |
16 |
72,775,660 (GRCm39) |
missense |
probably benign |
|
|
R2433:Robo1
|
UTSW |
16 |
72,767,127 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3084:Robo1
|
UTSW |
16 |
72,801,625 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3085:Robo1
|
UTSW |
16 |
72,798,898 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3150:Robo1
|
UTSW |
16 |
72,767,157 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R3418:Robo1
|
UTSW |
16 |
72,832,805 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3610:Robo1
|
UTSW |
16 |
72,780,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3940:Robo1
|
UTSW |
16 |
72,806,631 (GRCm39) |
missense |
probably benign |
|
|
R3953:Robo1
|
UTSW |
16 |
72,821,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4692:Robo1
|
UTSW |
16 |
72,757,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4726:Robo1
|
UTSW |
16 |
72,768,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4814:Robo1
|
UTSW |
16 |
72,768,923 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4884:Robo1
|
UTSW |
16 |
72,701,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Robo1
|
UTSW |
16 |
72,776,756 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5150:Robo1
|
UTSW |
16 |
72,769,192 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5183:Robo1
|
UTSW |
16 |
72,539,038 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5360:Robo1
|
UTSW |
16 |
72,732,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5629:Robo1
|
UTSW |
16 |
72,780,598 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5804:Robo1
|
UTSW |
16 |
72,840,077 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6107:Robo1
|
UTSW |
16 |
72,780,717 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6127:Robo1
|
UTSW |
16 |
72,809,956 (GRCm39) |
missense |
probably benign |
|
|
R6128:Robo1
|
UTSW |
16 |
72,809,956 (GRCm39) |
missense |
probably benign |
|
|
R6129:Robo1
|
UTSW |
16 |
72,809,956 (GRCm39) |
missense |
probably benign |
|
|
R6191:Robo1
|
UTSW |
16 |
72,730,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6357:Robo1
|
UTSW |
16 |
72,767,190 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6408:Robo1
|
UTSW |
16 |
72,768,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6516:Robo1
|
UTSW |
16 |
72,821,241 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6600:Robo1
|
UTSW |
16 |
72,786,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6802:Robo1
|
UTSW |
16 |
72,730,201 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7105:Robo1
|
UTSW |
16 |
72,539,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7189:Robo1
|
UTSW |
16 |
72,757,039 (GRCm39) |
nonsense |
probably null |
|
|
R7290:Robo1
|
UTSW |
16 |
72,801,408 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7296:Robo1
|
UTSW |
16 |
72,786,519 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Robo1
|
UTSW |
16 |
72,767,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7605:Robo1
|
UTSW |
16 |
72,821,189 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7607:Robo1
|
UTSW |
16 |
72,360,626 (GRCm39) |
missense |
|
|
|
R7634:Robo1
|
UTSW |
16 |
72,839,866 (GRCm39) |
splice site |
probably null |
|
|
R7636:Robo1
|
UTSW |
16 |
72,360,615 (GRCm39) |
missense |
|
|
|
R7857:Robo1
|
UTSW |
16 |
72,767,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7966:Robo1
|
UTSW |
16 |
72,780,760 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7997:Robo1
|
UTSW |
16 |
72,701,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8101:Robo1
|
UTSW |
16 |
72,775,469 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8191:Robo1
|
UTSW |
16 |
72,730,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8218:Robo1
|
UTSW |
16 |
72,786,678 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8228:Robo1
|
UTSW |
16 |
72,809,768 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8292:Robo1
|
UTSW |
16 |
72,769,420 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8298:Robo1
|
UTSW |
16 |
72,769,020 (GRCm39) |
intron |
probably benign |
|
|
R8332:Robo1
|
UTSW |
16 |
72,775,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Robo1
|
UTSW |
16 |
72,821,385 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8492:Robo1
|
UTSW |
16 |
72,809,911 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8730:Robo1
|
UTSW |
16 |
72,786,495 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8774:Robo1
|
UTSW |
16 |
72,832,719 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774-TAIL:Robo1
|
UTSW |
16 |
72,832,719 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8776:Robo1
|
UTSW |
16 |
72,821,141 (GRCm39) |
nonsense |
probably null |
|
|
R8776-TAIL:Robo1
|
UTSW |
16 |
72,821,141 (GRCm39) |
nonsense |
probably null |
|
|
R8913:Robo1
|
UTSW |
16 |
72,701,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9003:Robo1
|
UTSW |
16 |
72,539,002 (GRCm39) |
splice site |
probably benign |
|
|
R9246:Robo1
|
UTSW |
16 |
72,769,178 (GRCm39) |
missense |
probably benign |
|
|
R9451:Robo1
|
UTSW |
16 |
72,803,718 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9509:Robo1
|
UTSW |
16 |
72,759,167 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9652:Robo1
|
UTSW |
16 |
72,821,330 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9653:Robo1
|
UTSW |
16 |
72,821,330 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9749:Robo1
|
UTSW |
16 |
72,105,257 (GRCm39) |
start gained |
probably benign |
|
|
Z1176:Robo1
|
UTSW |
16 |
72,774,688 (GRCm39) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTCTGTAGTGAGACCTTTAACC -3'
(R):5'- ACTTACTAGCTACCTCCAGCG -3'
Sequencing Primer
(F):5'- GAGACCTTTAACCGATTTTCAGATGG -3'
(R):5'- TACCTCCAGCGATGCGTTG -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation