Mutagenetix > Incidental Mutation

Incidental Mutation 'R8936:Cul9'

680682

Institutional Source

Beutler Lab

Gene Symbol

Cul9

Ensembl Gene

ENSMUSG00000040327

Gene Name

cullin 9

Synonyms

Parc, 1810035I07Rik

MMRRC Submission

068779-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.198) question?

Stock #

R8936 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

46811535-46857314 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 46839528 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Cysteine at position 817 (S817C)

Ref Sequence

ENSEMBL: ENSMUSP00000138418 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000066026] [ENSMUST00000182485]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000066026
AA Change: S817C

PolyPhen 2 Score 0.816 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000067736
Gene: ENSMUSG00000040327
AA Change: S817C

Domain	Start	End	E-Value	Type
low complexity region	46	61	N/A	INTRINSIC
low complexity region	119	131	N/A	INTRINSIC
low complexity region	345	357	N/A	INTRINSIC
Pfam:Cul7	367	441	1e-35	PFAM
low complexity region	447	460	N/A	INTRINSIC
low complexity region	525	540	N/A	INTRINSIC
low complexity region	845	860	N/A	INTRINSIC
low complexity region	873	880	N/A	INTRINSIC
APC10	1166	1325	1.97e-56	SMART
low complexity region	1437	1450	N/A	INTRINSIC
low complexity region	1563	1578	N/A	INTRINSIC
low complexity region	1646	1671	N/A	INTRINSIC
Cullin_Nedd8	1867	1950	7.55e-6	SMART
Blast:RING	2074	2122	2e-13	BLAST
IBR	2144	2207	8.99e-14	SMART
IBR	2228	2283	4.66e-2	SMART
low complexity region	2503	2520	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182485
AA Change: S817C

PolyPhen 2 Score 0.816 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000138418
Gene: ENSMUSG00000040327
AA Change: S817C

Domain	Start	End	E-Value	Type
low complexity region	46	61	N/A	INTRINSIC
low complexity region	119	131	N/A	INTRINSIC
low complexity region	345	357	N/A	INTRINSIC
Pfam:Cul7	367	442	1.4e-33	PFAM
low complexity region	447	460	N/A	INTRINSIC
low complexity region	525	540	N/A	INTRINSIC
low complexity region	845	860	N/A	INTRINSIC
low complexity region	873	880	N/A	INTRINSIC
APC10	1166	1325	1.97e-56	SMART
low complexity region	1437	1450	N/A	INTRINSIC
low complexity region	1563	1578	N/A	INTRINSIC
low complexity region	1646	1671	N/A	INTRINSIC
Cullin_Nedd8	1867	1950	7.55e-6	SMART
Blast:RING	2074	2122	3e-13	BLAST
IBR	2144	2207	8.99e-14	SMART
IBR	2228	2283	4.66e-2	SMART
coiled coil region	2461	2497	N/A	INTRINSIC
low complexity region	2513	2530	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.7%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 85 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc2	A	G	19: 43,797,101 (GRCm39)	K491E	probably benign	Het
Abcd3	T	C	3: 121,569,117 (GRCm39)	I374V	probably benign	Het
Adam34	G	A	8: 44,104,439 (GRCm39)	T402I	probably benign	Het
Angptl7	G	T	4: 148,581,790 (GRCm39)	H199N	probably benign	Het
Ankrd11	A	G	8: 123,621,840 (GRCm39)	C671R	possibly damaging	Het
Anxa7	G	A	14: 20,521,495 (GRCm39)	P67L	unknown	Het
Ap3d1	T	A	10: 80,547,952 (GRCm39)	Q913H	probably benign	Het
Arhgef37	A	G	18: 61,656,948 (GRCm39)	I39T	probably damaging	Het
Armh4	G	A	14: 50,008,024 (GRCm39)	T483I	probably damaging	Het
C3ar1	T	A	6: 122,828,044 (GRCm39)	T58S	probably damaging	Het
Caap1	A	T	4: 94,389,332 (GRCm39)	L334Q	probably damaging	Het
Ccr1	A	T	9: 123,763,882 (GRCm39)	I216K	probably damaging	Het
Cdh9	T	A	15: 16,831,162 (GRCm39)		probably null	Het
Cept1	A	G	3: 106,411,921 (GRCm39)	F351S	possibly damaging	Het
Cfap61	A	G	2: 145,791,879 (GRCm39)	D112G	possibly damaging	Het
Dido1	A	G	2: 180,303,195 (GRCm39)	S1570P	probably benign	Het
Disc1	A	G	8: 125,814,754 (GRCm39)	D206G	probably damaging	Het
Dock5	T	A	14: 68,083,439 (GRCm39)	R157*	probably null	Het
Dpp6	A	G	5: 27,926,140 (GRCm39)	D738G	probably damaging	Het
Enpep	A	G	3: 129,125,884 (GRCm39)	F83L	possibly damaging	Het
F10	G	T	8: 13,095,086 (GRCm39)	W81L	probably damaging	Het
Fam217a	T	C	13: 35,095,147 (GRCm39)	D356G	probably damaging	Het
Fes	T	C	7: 80,031,473 (GRCm39)	E467G	probably damaging	Het
Fignl2	A	T	15: 100,951,339 (GRCm39)	D314E	unknown	Het
Foxh1	T	C	15: 76,552,719 (GRCm39)		probably benign	Het
Gdpd5	T	C	7: 99,109,199 (GRCm39)	L573P	probably benign	Het
Gigyf1	T	A	5: 137,523,469 (GRCm39)	S934T	probably damaging	Het
Gm7356	C	T	17: 14,221,937 (GRCm39)	V31I	probably benign	Het
Hoatz	A	G	9: 51,011,298 (GRCm39)		probably null	Het
Hoxa2	C	A	6: 52,140,517 (GRCm39)	K156N	probably damaging	Het
Ifi203	G	A	1: 173,756,857 (GRCm39)		probably benign	Het
Il5ra	A	T	6: 106,692,604 (GRCm39)	D380E	possibly damaging	Het
Ino80c	C	A	18: 24,254,865 (GRCm39)		probably benign	Het
Kif18a	T	A	2: 109,163,966 (GRCm39)	W772R	probably benign	Het
Lipo3	G	T	19: 33,557,880 (GRCm39)	Q171K	probably damaging	Het
Mga	A	T	2: 119,794,709 (GRCm39)	T2798S	probably damaging	Het
Msantd5l	A	G	11: 51,145,249 (GRCm39)	S113P	probably damaging	Het
Mybpc1	T	A	10: 88,394,437 (GRCm39)	T297S	probably benign	Het
Myh7	T	G	14: 55,228,440 (GRCm39)	Q222P	probably benign	Het
N4bp2l2	T	C	5: 150,585,362 (GRCm39)	D206G	probably benign	Het
Nacc2	G	C	2: 25,952,216 (GRCm39)	T380S	probably benign	Het
Niban3	T	A	8: 72,060,307 (GRCm39)		probably benign	Het
Nkpd1	T	A	7: 19,255,875 (GRCm39)	D186E	probably damaging	Het
Nol10	A	T	12: 17,466,863 (GRCm39)	E581V	probably benign	Het
Ntrk1	A	T	3: 87,693,366 (GRCm39)	N255K	possibly damaging	Het
Nudt5	T	G	2: 5,869,228 (GRCm39)	D151E	probably benign	Het
Obscn	A	T	11: 58,892,858 (GRCm39)	L6796Q	probably benign	Het
Or10p21	C	T	10: 128,847,802 (GRCm39)	A216V	probably benign	Het
Or4k2	A	G	14: 50,423,999 (GRCm39)	I225T	possibly damaging	Het
Oxct2b	A	G	4: 123,010,838 (GRCm39)	T253A	probably benign	Het
Patl1	G	A	19: 11,891,725 (GRCm39)	C10Y	probably damaging	Het
Pikfyve	A	G	1: 65,310,427 (GRCm39)	R1905G	possibly damaging	Het
Pkhd1l1	A	G	15: 44,402,312 (GRCm39)	E2228G	possibly damaging	Het
Plcg1	A	G	2: 160,589,986 (GRCm39)	K135E	probably benign	Het
Proz	A	G	8: 13,115,319 (GRCm39)	T112A	probably benign	Het
Prune2	A	G	19: 17,099,199 (GRCm39)	N1568D	probably benign	Het
Rbm4	A	G	19: 4,837,539 (GRCm39)	V431A	probably benign	Het
Rgs19	G	T	2: 181,333,058 (GRCm39)	C40*	probably null	Het
Rimbp3	T	A	16: 17,030,884 (GRCm39)	I1436K	probably benign	Het
Rnps1	T	A	17: 24,641,176 (GRCm39)	M192K	probably damaging	Het
Rrad	C	T	8: 105,355,222 (GRCm39)	R262Q	possibly damaging	Het
Slc17a9	G	A	2: 180,380,210 (GRCm39)	V318I	probably benign	Het
Slc5a12	A	G	2: 110,467,455 (GRCm39)	I412V	probably damaging	Het
Smc4	T	A	3: 68,925,491 (GRCm39)	N329K	probably benign	Het
St3gal4	G	A	9: 34,964,723 (GRCm39)	R165W	probably damaging	Het
Strbp	G	A	2: 37,493,949 (GRCm39)	R375*	probably null	Het
Tacc2	A	G	7: 130,228,367 (GRCm39)	N1684S	possibly damaging	Het
Tet1	A	T	10: 62,676,063 (GRCm39)	L671*	probably null	Het
Tex2	C	A	11: 106,458,144 (GRCm39)	E429*	probably null	Het
Tgm4	T	C	9: 122,869,541 (GRCm39)	I40T	possibly damaging	Het
Tmem132d	C	T	5: 127,869,676 (GRCm39)	D553N	probably damaging	Het
Tnks	A	T	8: 35,320,501 (GRCm39)	Y723*	probably null	Het
Tnks1bp1	A	T	2: 84,894,320 (GRCm39)	T1416S	probably benign	Het
Tnxb	T	A	17: 34,904,646 (GRCm39)	L1137Q	probably damaging	Het
Tor4a	A	C	2: 25,085,202 (GRCm39)	C68G	probably damaging	Het
Tubb2b	A	C	13: 34,312,445 (GRCm39)	V116G	probably damaging	Het
Upb1	T	A	10: 75,250,827 (GRCm39)	S99T	probably benign	Het
Vmn1r31	T	A	6: 58,449,083 (GRCm39)	I261F	unknown	Het
Vmn1r53	T	C	6: 90,200,571 (GRCm39)	Y251C	probably benign	Het
Vmn2r58	T	C	7: 41,513,981 (GRCm39)	R221G		Het
Vmn2r88	A	T	14: 51,655,983 (GRCm39)	I740F	possibly damaging	Het
Zfp644	C	T	5: 106,783,503 (GRCm39)	G1015R	probably damaging	Het
Zfy1	T	C	Y: 738,726 (GRCm39)	D160G	unknown	Het
Zscan25	T	A	5: 145,223,200 (GRCm39)	V156E	probably damaging	Het
Zyg11b	A	T	4: 108,109,356 (GRCm39)	F443I		Het

Other mutations in Cul9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00087:Cul9	APN	17	46,836,635 (GRCm39)	missense	probably damaging	1.00
IGL00330:Cul9	APN	17	46,821,767 (GRCm39)	splice site	probably benign
IGL00726:Cul9	APN	17	46,839,022 (GRCm39)	missense	probably damaging	1.00
IGL01020:Cul9	APN	17	46,849,949 (GRCm39)	missense	probably damaging	1.00
IGL01358:Cul9	APN	17	46,849,240 (GRCm39)	missense	probably damaging	1.00
IGL01410:Cul9	APN	17	46,839,572 (GRCm39)	missense	probably damaging	0.99
IGL01781:Cul9	APN	17	46,850,230 (GRCm39)	missense	probably benign
IGL01873:Cul9	APN	17	46,813,378 (GRCm39)	missense	probably damaging	0.99
IGL02117:Cul9	APN	17	46,851,301 (GRCm39)	missense	probably benign	0.00
IGL02300:Cul9	APN	17	46,831,958 (GRCm39)	splice site	probably benign
IGL02426:Cul9	APN	17	46,834,184 (GRCm39)	missense	possibly damaging	0.95
IGL02427:Cul9	APN	17	46,813,558 (GRCm39)	missense	possibly damaging	0.69
IGL02496:Cul9	APN	17	46,851,302 (GRCm39)	missense	possibly damaging	0.72
IGL03008:Cul9	APN	17	46,813,623 (GRCm39)	splice site	probably benign
IGL03059:Cul9	APN	17	46,849,913 (GRCm39)	missense	probably damaging	0.98
IGL03302:Cul9	APN	17	46,837,566 (GRCm39)	missense	probably damaging	0.98
bottlenose	UTSW	17	46,811,770 (GRCm39)	missense	possibly damaging	0.79
flipper	UTSW	17	46,836,818 (GRCm39)	missense	probably benign	0.05
orca	UTSW	17	46,836,061 (GRCm39)	missense	probably damaging	1.00
FR4340:Cul9	UTSW	17	46,811,779 (GRCm39)	small insertion	probably benign
FR4449:Cul9	UTSW	17	46,811,782 (GRCm39)	small insertion	probably benign
FR4737:Cul9	UTSW	17	46,811,784 (GRCm39)	small insertion	probably benign
FR4737:Cul9	UTSW	17	46,811,772 (GRCm39)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,811,779 (GRCm39)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,811,776 (GRCm39)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,811,774 (GRCm39)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,811,782 (GRCm39)	small insertion	probably benign
R0012:Cul9	UTSW	17	46,849,436 (GRCm39)	missense	probably benign	0.26
R0079:Cul9	UTSW	17	46,848,589 (GRCm39)	nonsense	probably null
R0143:Cul9	UTSW	17	46,837,336 (GRCm39)	missense	possibly damaging	0.65
R0390:Cul9	UTSW	17	46,839,515 (GRCm39)	missense	probably benign	0.34
R0401:Cul9	UTSW	17	46,852,630 (GRCm39)	missense	probably damaging	1.00
R0529:Cul9	UTSW	17	46,831,394 (GRCm39)	splice site	probably benign
R0815:Cul9	UTSW	17	46,848,748 (GRCm39)	splice site	probably null
R0863:Cul9	UTSW	17	46,848,748 (GRCm39)	splice site	probably null
R0972:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1173:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1216:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1217:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1261:Cul9	UTSW	17	46,836,708 (GRCm39)	missense	probably damaging	1.00
R1278:Cul9	UTSW	17	46,811,775 (GRCm39)	small deletion	probably benign
R1281:Cul9	UTSW	17	46,822,460 (GRCm39)	missense	probably damaging	1.00
R1349:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1372:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1403:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1403:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1405:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1405:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R1467:Cul9	UTSW	17	46,836,299 (GRCm39)	missense	probably damaging	1.00
R1467:Cul9	UTSW	17	46,836,299 (GRCm39)	missense	probably damaging	1.00
R1482:Cul9	UTSW	17	46,819,473 (GRCm39)	missense	probably damaging	0.99
R1491:Cul9	UTSW	17	46,849,490 (GRCm39)	nonsense	probably null
R1618:Cul9	UTSW	17	46,836,818 (GRCm39)	missense	probably benign	0.05
R1641:Cul9	UTSW	17	46,854,486 (GRCm39)	missense	possibly damaging	0.96
R1679:Cul9	UTSW	17	46,832,082 (GRCm39)	missense	possibly damaging	0.90
R1771:Cul9	UTSW	17	46,848,738 (GRCm39)	missense	probably benign	0.41
R1803:Cul9	UTSW	17	46,814,023 (GRCm39)	missense	probably damaging	1.00
R2020:Cul9	UTSW	17	46,833,101 (GRCm39)	missense	probably damaging	1.00
R2046:Cul9	UTSW	17	46,854,659 (GRCm39)	missense	probably damaging	1.00
R2056:Cul9	UTSW	17	46,854,298 (GRCm39)	missense	probably benign
R2088:Cul9	UTSW	17	46,837,575 (GRCm39)	missense	probably damaging	1.00
R2415:Cul9	UTSW	17	46,854,364 (GRCm39)	missense	probably benign
R2925:Cul9	UTSW	17	46,821,907 (GRCm39)	missense	probably benign	0.08
R2964:Cul9	UTSW	17	46,813,154 (GRCm39)	missense	probably damaging	0.96
R2965:Cul9	UTSW	17	46,813,154 (GRCm39)	missense	probably damaging	0.96
R3690:Cul9	UTSW	17	46,814,957 (GRCm39)	splice site	probably null
R3847:Cul9	UTSW	17	46,836,061 (GRCm39)	missense	probably damaging	1.00
R4437:Cul9	UTSW	17	46,813,085 (GRCm39)	missense	probably damaging	1.00
R4470:Cul9	UTSW	17	46,849,262 (GRCm39)	missense	probably benign	0.00
R4540:Cul9	UTSW	17	46,814,015 (GRCm39)	missense	probably null	0.98
R4555:Cul9	UTSW	17	46,812,755 (GRCm39)	missense	possibly damaging	0.82
R4604:Cul9	UTSW	17	46,841,072 (GRCm39)	missense	probably damaging	0.99
R4646:Cul9	UTSW	17	46,849,943 (GRCm39)	nonsense	probably null
R4799:Cul9	UTSW	17	46,811,770 (GRCm39)	missense	possibly damaging	0.79
R4822:Cul9	UTSW	17	46,840,977 (GRCm39)	missense	probably benign	0.01
R4964:Cul9	UTSW	17	46,849,451 (GRCm39)	missense	probably damaging	1.00
R4965:Cul9	UTSW	17	46,849,451 (GRCm39)	missense	probably damaging	1.00
R5027:Cul9	UTSW	17	46,811,708 (GRCm39)	missense	probably damaging	0.99
R5185:Cul9	UTSW	17	46,836,758 (GRCm39)	missense	possibly damaging	0.95
R5237:Cul9	UTSW	17	46,854,393 (GRCm39)	missense	probably benign	0.00
R5278:Cul9	UTSW	17	46,821,799 (GRCm39)	missense	probably damaging	1.00
R5361:Cul9	UTSW	17	46,811,775 (GRCm39)	small deletion	probably benign
R5455:Cul9	UTSW	17	46,821,772 (GRCm39)	splice site	probably null
R5592:Cul9	UTSW	17	46,831,517 (GRCm39)	missense	probably benign	0.00
R5597:Cul9	UTSW	17	46,813,591 (GRCm39)	missense	possibly damaging	0.56
R5613:Cul9	UTSW	17	46,814,770 (GRCm39)	missense	probably damaging	1.00
R6122:Cul9	UTSW	17	46,832,854 (GRCm39)	missense	possibly damaging	0.72
R6135:Cul9	UTSW	17	46,832,379 (GRCm39)	missense	probably benign
R6352:Cul9	UTSW	17	46,822,241 (GRCm39)	missense	probably benign	0.00
R6376:Cul9	UTSW	17	46,819,489 (GRCm39)	missense	probably damaging	1.00
R6868:Cul9	UTSW	17	46,833,109 (GRCm39)	missense	possibly damaging	0.73
R6898:Cul9	UTSW	17	46,821,952 (GRCm39)	missense	possibly damaging	0.87
R7090:Cul9	UTSW	17	46,811,765 (GRCm39)	missense	probably damaging	0.96
R7193:Cul9	UTSW	17	46,849,423 (GRCm39)	missense	probably damaging	0.98
R7221:Cul9	UTSW	17	46,839,491 (GRCm39)	missense	probably damaging	0.99
R7291:Cul9	UTSW	17	46,851,359 (GRCm39)	missense	probably benign	0.00
R7320:Cul9	UTSW	17	46,821,835 (GRCm39)	missense	possibly damaging	0.80
R7348:Cul9	UTSW	17	46,821,919 (GRCm39)	missense	possibly damaging	0.89
R7463:Cul9	UTSW	17	46,831,402 (GRCm39)	splice site	probably null
R7480:Cul9	UTSW	17	46,848,738 (GRCm39)	missense	probably benign	0.41
R7573:Cul9	UTSW	17	46,830,836 (GRCm39)	missense	probably benign
R7582:Cul9	UTSW	17	46,821,905 (GRCm39)	missense	probably damaging	1.00
R7605:Cul9	UTSW	17	46,852,658 (GRCm39)	missense	probably damaging	0.99
R7684:Cul9	UTSW	17	46,820,815 (GRCm39)	missense	probably damaging	1.00
R7830:Cul9	UTSW	17	46,851,237 (GRCm39)	missense	probably benign	0.37
R7834:Cul9	UTSW	17	46,836,630 (GRCm39)	splice site	probably null
R8131:Cul9	UTSW	17	46,822,168 (GRCm39)	missense	probably damaging	1.00
R8192:Cul9	UTSW	17	46,849,273 (GRCm39)	missense	probably benign	0.01
R8231:Cul9	UTSW	17	46,831,427 (GRCm39)	missense	probably damaging	0.99
R8248:Cul9	UTSW	17	46,840,940 (GRCm39)	missense	probably damaging	0.99
R8504:Cul9	UTSW	17	46,814,506 (GRCm39)	missense	probably damaging	1.00
R8550:Cul9	UTSW	17	46,830,772 (GRCm39)	missense	probably damaging	1.00
R8716:Cul9	UTSW	17	46,838,840 (GRCm39)	missense	probably benign	0.28
R8769:Cul9	UTSW	17	46,832,828 (GRCm39)	missense	possibly damaging	0.85
R8893:Cul9	UTSW	17	46,811,775 (GRCm39)	small deletion	probably benign
R8904:Cul9	UTSW	17	46,831,427 (GRCm39)	missense	probably damaging	0.99
R8972:Cul9	UTSW	17	46,854,177 (GRCm39)	missense	probably damaging	1.00
R9003:Cul9	UTSW	17	46,836,001 (GRCm39)	missense	possibly damaging	0.78
R9012:Cul9	UTSW	17	46,854,447 (GRCm39)	missense	probably benign
R9056:Cul9	UTSW	17	46,854,696 (GRCm39)	missense	probably damaging	0.99
R9071:Cul9	UTSW	17	46,837,379 (GRCm39)	missense	probably benign
R9162:Cul9	UTSW	17	46,837,529 (GRCm39)	missense	probably benign	0.32
R9476:Cul9	UTSW	17	46,821,833 (GRCm39)	missense	probably damaging	1.00
R9526:Cul9	UTSW	17	46,841,026 (GRCm39)	missense	probably benign	0.41
R9563:Cul9	UTSW	17	46,820,897 (GRCm39)	missense	probably benign	0.01
R9568:Cul9	UTSW	17	46,831,044 (GRCm39)	missense	possibly damaging	0.56
R9610:Cul9	UTSW	17	46,830,823 (GRCm39)	missense	possibly damaging	0.96
R9611:Cul9	UTSW	17	46,830,823 (GRCm39)	missense	possibly damaging	0.96
R9705:Cul9	UTSW	17	46,854,226 (GRCm39)	missense	probably damaging	1.00
R9765:Cul9	UTSW	17	46,850,224 (GRCm39)	missense	probably benign	0.18
RF011:Cul9	UTSW	17	46,811,774 (GRCm39)	small insertion	probably benign
RF016:Cul9	UTSW	17	46,811,789 (GRCm39)	nonsense	probably null
RF026:Cul9	UTSW	17	46,811,795 (GRCm39)	nonsense	probably null
RF027:Cul9	UTSW	17	46,811,774 (GRCm39)	small insertion	probably benign
RF030:Cul9	UTSW	17	46,811,795 (GRCm39)	small insertion	probably benign
RF033:Cul9	UTSW	17	46,811,780 (GRCm39)	small insertion	probably benign
RF039:Cul9	UTSW	17	46,811,780 (GRCm39)	small insertion	probably benign
RF041:Cul9	UTSW	17	46,811,780 (GRCm39)	nonsense	probably null
RF042:Cul9	UTSW	17	46,851,541 (GRCm39)	frame shift	probably null
RF057:Cul9	UTSW	17	46,811,789 (GRCm39)	nonsense	probably null
Z1176:Cul9	UTSW	17	46,831,511 (GRCm39)	nonsense	probably null
Z1176:Cul9	UTSW	17	46,831,502 (GRCm39)	nonsense	probably null
Z1177:Cul9	UTSW	17	46,848,723 (GRCm39)	missense	probably benign	0.14

Predicted Primers

PCR Primer
(F):5'- ACAGCGAGGATTTAGAGTCTG -3'
(R):5'- TAACCGTGCAGCTACTCCAG -3'

Sequencing Primer
(F):5'- GTCTGGAGGGTAAACTCTAACCC -3'
(R):5'- GCAGCTACTCCAGGGTTTG -3'

Posted On

2021-08-31