Incidental Mutation 'R8947:Uggt1'
| ID |
681335 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Uggt1
|
| Ensembl Gene |
ENSMUSG00000037470 |
| Gene Name |
UDP-glucose glycoprotein glucosyltransferase 1 |
| Synonyms |
C820010P03Rik, 0910001L17Rik, Ugcgl1, A930007H10Rik |
| MMRRC Submission |
068785-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.470)
|
| Stock # |
R8947 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
36179109-36283407 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 36197229 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1225
(T1225A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037930
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046875]
[ENSMUST00000173166]
[ENSMUST00000174266]
|
| AlphaFold |
Q6P5E4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046875
AA Change: T1225A
PolyPhen 2
Score 0.117 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000037930
Gene: ENSMUSG00000037470
AA Change: T1225A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
42 |
N/A |
INTRINSIC |
|
Pfam:UDP-g_GGTase
|
44 |
1222 |
N/A |
PFAM |
|
SCOP:d1ga8a_
|
1256 |
1521 |
3e-45 |
SMART |
|
Blast:BROMO
|
1414 |
1453 |
3e-17 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173166
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174224
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174266
|
| SMART Domains |
Protein: ENSMUSP00000134640
Gene: ENSMUSG00000037470
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
97 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0599 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
99% (93/94) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
PHENOTYPE: Heterozygous KO reduces susceptibility to and morbidity of RNA virus infection. Homozygous KO is embryonic lethal. The peptide is a folding sensor for glycoproteins in the ER. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
A |
16: 4,665,292 (GRCm39) |
F141L |
unknown |
Het |
| A2ml1 |
G |
T |
6: 128,529,219 (GRCm39) |
N974K |
probably damaging |
Het |
| Abcg8 |
T |
C |
17: 84,999,246 (GRCm39) |
L114P |
probably damaging |
Het |
| Akt3 |
A |
T |
1: 176,958,645 (GRCm39) |
W22R |
probably damaging |
Het |
| Ank2 |
C |
T |
3: 126,736,396 (GRCm39) |
|
probably benign |
Het |
| Ap1g1 |
C |
T |
8: 110,589,964 (GRCm39) |
|
probably benign |
Het |
| Arhgef19 |
T |
A |
4: 140,973,618 (GRCm39) |
V35E |
possibly damaging |
Het |
| Baz2b |
T |
C |
2: 59,778,583 (GRCm39) |
D759G |
probably benign |
Het |
| BC051665 |
C |
A |
13: 60,930,004 (GRCm39) |
G320W |
probably damaging |
Het |
| Bche |
T |
A |
3: 73,608,761 (GRCm39) |
T222S |
probably damaging |
Het |
| C8a |
T |
C |
4: 104,679,326 (GRCm39) |
D444G |
probably damaging |
Het |
| Cacna1e |
A |
T |
1: 154,277,896 (GRCm39) |
S2019T |
probably benign |
Het |
| Carm1 |
T |
C |
9: 21,497,749 (GRCm39) |
I373T |
probably damaging |
Het |
| Ccdc39 |
T |
C |
3: 33,869,609 (GRCm39) |
|
probably benign |
Het |
| Clic5 |
A |
T |
17: 44,553,148 (GRCm39) |
|
probably benign |
Het |
| Cntn3 |
A |
G |
6: 102,414,864 (GRCm39) |
F28L |
probably damaging |
Het |
| Col6a5 |
C |
T |
9: 105,822,833 (GRCm39) |
E175K |
unknown |
Het |
| Cpb2 |
T |
C |
14: 75,515,627 (GRCm39) |
Y352H |
probably damaging |
Het |
| Cpeb3 |
A |
T |
19: 37,152,366 (GRCm39) |
D3E |
probably damaging |
Het |
| Ctsl |
T |
C |
13: 64,514,840 (GRCm39) |
T155A |
probably damaging |
Het |
| Cygb |
C |
T |
11: 116,540,645 (GRCm39) |
A114T |
probably damaging |
Het |
| Cyp11a1 |
T |
C |
9: 57,924,738 (GRCm39) |
V17A |
probably benign |
Het |
| Dhcr7 |
T |
G |
7: 143,400,959 (GRCm39) |
I374S |
probably damaging |
Het |
| Dhx36 |
T |
C |
3: 62,380,387 (GRCm39) |
R807G |
probably benign |
Het |
| Diaph1 |
A |
T |
18: 37,986,754 (GRCm39) |
V1077E |
probably damaging |
Het |
| Ehmt2 |
A |
G |
17: 35,127,280 (GRCm39) |
E131G |
possibly damaging |
Het |
| Evpl |
A |
G |
11: 116,112,164 (GRCm39) |
I1842T |
probably damaging |
Het |
| Fastk |
C |
A |
5: 24,646,649 (GRCm39) |
C294F |
probably damaging |
Het |
| Fndc5 |
T |
C |
4: 129,030,929 (GRCm39) |
C20R |
probably benign |
Het |
| Gm7298 |
C |
A |
6: 121,757,553 (GRCm39) |
Q1053K |
possibly damaging |
Het |
| Gm8362 |
A |
G |
14: 18,151,405 (GRCm39) |
|
probably null |
Het |
| Gmps |
T |
A |
3: 63,906,098 (GRCm39) |
I465N |
probably damaging |
Het |
| Heatr4 |
T |
G |
12: 84,001,431 (GRCm39) |
M904L |
probably benign |
Het |
| Hhip |
T |
A |
8: 80,771,785 (GRCm39) |
D175V |
probably damaging |
Het |
| Hmcn2 |
G |
A |
2: 31,278,220 (GRCm39) |
V1641M |
probably damaging |
Het |
| Hoxa5 |
T |
G |
6: 52,179,776 (GRCm39) |
T200P |
probably damaging |
Het |
| Ift122 |
C |
A |
6: 115,901,368 (GRCm39) |
A1050D |
probably benign |
Het |
| Igf2bp2 |
C |
A |
16: 21,897,473 (GRCm39) |
E247* |
probably null |
Het |
| Irak1bp1 |
T |
A |
9: 82,728,846 (GRCm39) |
L259H |
probably damaging |
Het |
| Irgm1 |
G |
A |
11: 48,759,575 (GRCm39) |
|
probably benign |
Het |
| Itih1 |
A |
T |
14: 30,657,866 (GRCm39) |
|
probably benign |
Het |
| Itpk1 |
A |
T |
12: 102,536,582 (GRCm39) |
C355S |
probably benign |
Het |
| Kcng4 |
T |
C |
8: 120,352,452 (GRCm39) |
E486G |
possibly damaging |
Het |
| Kif20b |
T |
C |
19: 34,918,629 (GRCm39) |
V671A |
possibly damaging |
Het |
| Kif28 |
T |
G |
1: 179,544,320 (GRCm39) |
I345L |
possibly damaging |
Het |
| Klri2 |
C |
G |
6: 129,710,742 (GRCm39) |
|
probably null |
Het |
| Kntc1 |
T |
C |
5: 123,925,041 (GRCm39) |
V1118A |
probably benign |
Het |
| Lpin2 |
T |
A |
17: 71,511,871 (GRCm39) |
I34N |
probably benign |
Het |
| Lrch3 |
T |
A |
16: 32,802,199 (GRCm39) |
V264D |
possibly damaging |
Het |
| Lrrk2 |
C |
T |
15: 91,586,473 (GRCm39) |
Q430* |
probably null |
Het |
| Map10 |
T |
G |
8: 126,397,839 (GRCm39) |
S411A |
probably benign |
Het |
| Map1a |
A |
T |
2: 121,135,450 (GRCm39) |
I2089F |
probably benign |
Het |
| Med12l |
T |
A |
3: 58,984,443 (GRCm39) |
|
probably benign |
Het |
| Mypn |
T |
A |
10: 63,005,156 (GRCm39) |
Q317L |
probably damaging |
Het |
| Ncan |
T |
A |
8: 70,555,171 (GRCm39) |
I999F |
probably damaging |
Het |
| Nmrk2 |
C |
A |
10: 81,035,539 (GRCm39) |
R134L |
probably damaging |
Het |
| Or4k42 |
C |
T |
2: 111,320,042 (GRCm39) |
V154I |
probably benign |
Het |
| Or51f1d |
T |
A |
7: 102,701,315 (GRCm39) |
V270E |
probably damaging |
Het |
| Or5k17 |
T |
C |
16: 58,746,433 (GRCm39) |
N167S |
probably benign |
Het |
| Or6z7 |
A |
G |
7: 6,483,246 (GRCm39) |
V303A |
probably benign |
Het |
| Or8b1c |
T |
A |
9: 38,384,685 (GRCm39) |
I214N |
probably damaging |
Het |
| Osbpl1a |
A |
G |
18: 12,899,858 (GRCm39) |
|
probably null |
Het |
| Pcdh1 |
T |
C |
18: 38,332,073 (GRCm39) |
D310G |
possibly damaging |
Het |
| Pkn2 |
C |
T |
3: 142,517,674 (GRCm39) |
|
probably null |
Het |
| Plch1 |
T |
A |
3: 63,691,547 (GRCm39) |
M31L |
probably damaging |
Het |
| Polg2 |
A |
G |
11: 106,659,170 (GRCm39) |
F448L |
probably damaging |
Het |
| Ppp4r3b |
A |
G |
11: 29,150,758 (GRCm39) |
T475A |
possibly damaging |
Het |
| Prdm13 |
C |
T |
4: 21,678,817 (GRCm39) |
E558K |
probably damaging |
Het |
| Prdm9 |
T |
A |
17: 15,764,270 (GRCm39) |
I837F |
possibly damaging |
Het |
| R3hdm1 |
T |
A |
1: 128,102,694 (GRCm39) |
M125K |
possibly damaging |
Het |
| Rbm39 |
A |
T |
2: 155,990,276 (GRCm39) |
V468E |
probably damaging |
Het |
| Rnasel |
T |
A |
1: 153,630,777 (GRCm39) |
V431E |
probably damaging |
Het |
| Rps2 |
T |
A |
17: 24,940,227 (GRCm39) |
D220E |
probably benign |
Het |
| Rsf1 |
T |
C |
7: 97,331,059 (GRCm39) |
|
probably benign |
Het |
| Rsph10b |
G |
T |
5: 143,913,952 (GRCm39) |
A710S |
probably benign |
Het |
| Sez6 |
A |
T |
11: 77,844,353 (GRCm39) |
T59S |
probably damaging |
Het |
| Sf3b1 |
A |
T |
1: 55,039,444 (GRCm39) |
V727E |
probably damaging |
Het |
| Slit2 |
T |
G |
5: 48,407,140 (GRCm39) |
L857R |
probably damaging |
Het |
| Spata31g1 |
T |
A |
4: 42,972,097 (GRCm39) |
S477T |
probably benign |
Het |
| Sspo |
T |
G |
6: 48,425,504 (GRCm39) |
C42G |
probably damaging |
Het |
| Strc |
C |
T |
2: 121,201,470 (GRCm39) |
D1245N |
probably benign |
Het |
| Supv3l1 |
T |
A |
10: 62,268,118 (GRCm39) |
T576S |
probably benign |
Het |
| Tecrl |
C |
T |
5: 83,461,154 (GRCm39) |
R101Q |
probably benign |
Het |
| Tmeff2 |
A |
G |
1: 51,220,952 (GRCm39) |
Y309C |
probably damaging |
Het |
| Tmem43 |
T |
A |
6: 91,462,362 (GRCm39) |
W316R |
probably damaging |
Het |
| Tmigd3 |
T |
C |
3: 105,821,554 (GRCm39) |
V141A |
probably benign |
Het |
| Trav9-1 |
T |
C |
14: 53,725,584 (GRCm39) |
F8L |
probably benign |
Het |
| Trbv5 |
T |
G |
6: 41,039,641 (GRCm39) |
F82C |
probably damaging |
Het |
| Ubtf |
T |
C |
11: 102,205,802 (GRCm39) |
N41S |
possibly damaging |
Het |
| Vmn1r72 |
T |
C |
7: 11,403,807 (GRCm39) |
R214G |
possibly damaging |
Het |
| Vmn2r12 |
T |
G |
5: 109,234,522 (GRCm39) |
K563N |
possibly damaging |
Het |
| Vmn2r83 |
T |
C |
10: 79,304,873 (GRCm39) |
S28P |
probably benign |
Het |
| Vwa8 |
T |
G |
14: 79,438,552 (GRCm39) |
L1875R |
probably damaging |
Het |
| Xrcc6 |
T |
A |
15: 81,913,866 (GRCm39) |
V64E |
probably damaging |
Het |
| Zfp292 |
T |
C |
4: 34,811,835 (GRCm39) |
Y403C |
probably damaging |
Het |
| Zfp955a |
A |
T |
17: 33,460,955 (GRCm39) |
H392Q |
probably damaging |
Het |
| Zfyve19 |
T |
C |
2: 119,041,290 (GRCm39) |
S69P |
probably damaging |
Het |
|
| Other mutations in Uggt1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00091:Uggt1
|
APN |
1 |
36,218,633 (GRCm39) |
splice site |
probably benign |
|
|
IGL00817:Uggt1
|
APN |
1 |
36,225,013 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01395:Uggt1
|
APN |
1 |
36,194,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01609:Uggt1
|
APN |
1 |
36,221,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01619:Uggt1
|
APN |
1 |
36,200,775 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02077:Uggt1
|
APN |
1 |
36,215,875 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02313:Uggt1
|
APN |
1 |
36,223,565 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02341:Uggt1
|
APN |
1 |
36,203,600 (GRCm39) |
makesense |
probably null |
|
|
IGL02346:Uggt1
|
APN |
1 |
36,218,751 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02447:Uggt1
|
APN |
1 |
36,189,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02883:Uggt1
|
APN |
1 |
36,216,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02930:Uggt1
|
APN |
1 |
36,196,537 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03153:Uggt1
|
APN |
1 |
36,241,899 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03162:Uggt1
|
APN |
1 |
36,247,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03170:Uggt1
|
APN |
1 |
36,202,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03266:Uggt1
|
APN |
1 |
36,189,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
K3955:Uggt1
|
UTSW |
1 |
36,201,434 (GRCm39) |
missense |
probably benign |
0.37 |
|
R0037:Uggt1
|
UTSW |
1 |
36,225,013 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0037:Uggt1
|
UTSW |
1 |
36,225,013 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0167:Uggt1
|
UTSW |
1 |
36,209,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0373:Uggt1
|
UTSW |
1 |
36,218,751 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0502:Uggt1
|
UTSW |
1 |
36,199,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0546:Uggt1
|
UTSW |
1 |
36,235,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0610:Uggt1
|
UTSW |
1 |
36,204,587 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Uggt1
|
UTSW |
1 |
36,194,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0760:Uggt1
|
UTSW |
1 |
36,200,805 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0825:Uggt1
|
UTSW |
1 |
36,197,224 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0827:Uggt1
|
UTSW |
1 |
36,195,394 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0884:Uggt1
|
UTSW |
1 |
36,214,159 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1112:Uggt1
|
UTSW |
1 |
36,212,627 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1470:Uggt1
|
UTSW |
1 |
36,215,877 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1470:Uggt1
|
UTSW |
1 |
36,215,877 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1592:Uggt1
|
UTSW |
1 |
36,241,939 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1730:Uggt1
|
UTSW |
1 |
36,260,342 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1923:Uggt1
|
UTSW |
1 |
36,218,694 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1970:Uggt1
|
UTSW |
1 |
36,190,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2086:Uggt1
|
UTSW |
1 |
36,231,495 (GRCm39) |
missense |
probably null |
1.00 |
|
R2829:Uggt1
|
UTSW |
1 |
36,201,375 (GRCm39) |
missense |
probably benign |
0.38 |
|
R3431:Uggt1
|
UTSW |
1 |
36,249,140 (GRCm39) |
nonsense |
probably null |
|
|
R3432:Uggt1
|
UTSW |
1 |
36,249,140 (GRCm39) |
nonsense |
probably null |
|
|
R3725:Uggt1
|
UTSW |
1 |
36,221,588 (GRCm39) |
nonsense |
probably null |
|
|
R3880:Uggt1
|
UTSW |
1 |
36,215,885 (GRCm39) |
intron |
probably benign |
|
|
R4052:Uggt1
|
UTSW |
1 |
36,203,570 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4133:Uggt1
|
UTSW |
1 |
36,197,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4489:Uggt1
|
UTSW |
1 |
36,185,749 (GRCm39) |
nonsense |
probably null |
|
|
R4570:Uggt1
|
UTSW |
1 |
36,189,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4866:Uggt1
|
UTSW |
1 |
36,241,936 (GRCm39) |
nonsense |
probably null |
|
|
R4895:Uggt1
|
UTSW |
1 |
36,195,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4900:Uggt1
|
UTSW |
1 |
36,241,936 (GRCm39) |
nonsense |
probably null |
|
|
R5372:Uggt1
|
UTSW |
1 |
36,283,141 (GRCm39) |
splice site |
probably benign |
|
|
R5385:Uggt1
|
UTSW |
1 |
36,223,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5652:Uggt1
|
UTSW |
1 |
36,255,234 (GRCm39) |
nonsense |
probably null |
|
|
R5694:Uggt1
|
UTSW |
1 |
36,218,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5732:Uggt1
|
UTSW |
1 |
36,200,852 (GRCm39) |
splice site |
probably null |
|
|
R5893:Uggt1
|
UTSW |
1 |
36,266,709 (GRCm39) |
splice site |
probably null |
|
|
R6191:Uggt1
|
UTSW |
1 |
36,201,289 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6247:Uggt1
|
UTSW |
1 |
36,202,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6259:Uggt1
|
UTSW |
1 |
36,273,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6399:Uggt1
|
UTSW |
1 |
36,202,447 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6439:Uggt1
|
UTSW |
1 |
36,214,032 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6468:Uggt1
|
UTSW |
1 |
36,212,531 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6788:Uggt1
|
UTSW |
1 |
36,269,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7165:Uggt1
|
UTSW |
1 |
36,194,188 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7255:Uggt1
|
UTSW |
1 |
36,185,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7273:Uggt1
|
UTSW |
1 |
36,201,302 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7469:Uggt1
|
UTSW |
1 |
36,190,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7490:Uggt1
|
UTSW |
1 |
36,203,589 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7570:Uggt1
|
UTSW |
1 |
36,224,919 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7612:Uggt1
|
UTSW |
1 |
36,202,316 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7759:Uggt1
|
UTSW |
1 |
36,185,806 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7792:Uggt1
|
UTSW |
1 |
36,247,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7816:Uggt1
|
UTSW |
1 |
36,202,396 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7858:Uggt1
|
UTSW |
1 |
36,195,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Uggt1
|
UTSW |
1 |
36,247,115 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8040:Uggt1
|
UTSW |
1 |
36,250,554 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8093:Uggt1
|
UTSW |
1 |
36,266,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8245:Uggt1
|
UTSW |
1 |
36,204,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Uggt1
|
UTSW |
1 |
36,266,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8353:Uggt1
|
UTSW |
1 |
36,209,377 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8442:Uggt1
|
UTSW |
1 |
36,212,568 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8519:Uggt1
|
UTSW |
1 |
36,215,724 (GRCm39) |
splice site |
probably null |
|
|
R8529:Uggt1
|
UTSW |
1 |
36,223,513 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8730:Uggt1
|
UTSW |
1 |
36,236,624 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8917:Uggt1
|
UTSW |
1 |
36,185,735 (GRCm39) |
missense |
|
|
|
R9240:Uggt1
|
UTSW |
1 |
36,221,696 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9248:Uggt1
|
UTSW |
1 |
36,249,103 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9401:Uggt1
|
UTSW |
1 |
36,255,212 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9414:Uggt1
|
UTSW |
1 |
36,223,507 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9416:Uggt1
|
UTSW |
1 |
36,203,603 (GRCm39) |
missense |
|
|
|
R9441:Uggt1
|
UTSW |
1 |
36,260,306 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9489:Uggt1
|
UTSW |
1 |
36,273,886 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9563:Uggt1
|
UTSW |
1 |
36,204,627 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9605:Uggt1
|
UTSW |
1 |
36,273,886 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0022:Uggt1
|
UTSW |
1 |
36,204,636 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Z1088:Uggt1
|
UTSW |
1 |
36,213,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Uggt1
|
UTSW |
1 |
36,200,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Uggt1
|
UTSW |
1 |
36,194,154 (GRCm39) |
missense |
probably null |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCGTGGAAGAACACTTTCC -3'
(R):5'- ATGAACGCACTGCCACAGTC -3'
Sequencing Primer
(F):5'- TCTTCTCCAACTGAAAGGGC -3'
(R):5'- TGCCACAGTCCTGAGAGTCTG -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation