Incidental Mutation 'R8955:Ralgapb'
| ID |
681903 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapb
|
| Ensembl Gene |
ENSMUSG00000027652 |
| Gene Name |
Ral GTPase activating protein, beta subunit (non-catalytic) |
| Synonyms |
B230339M05Rik |
| MMRRC Submission |
068791-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8955 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
158251768-158341173 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to G
at 158337389 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Arginine
at position 1116
(T1116R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116481
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046274]
[ENSMUST00000109485]
[ENSMUST00000109486]
[ENSMUST00000141497]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000046274
AA Change: T1434R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000048430
Gene: ENSMUSG00000027652
AA Change: T1434R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
775 |
788 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1097 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1321 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109485
AA Change: T1450R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000105111
Gene: ENSMUSG00000027652
AA Change: T1450R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
637 |
N/A |
INTRINSIC |
|
low complexity region
|
791 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
936 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1325 |
1337 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000105112
Gene: ENSMUSG00000027652
AA Change: T1438R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000141497
AA Change: T1116R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000116481
Gene: ENSMUSG00000027652
AA Change: T1116R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
288 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
470 |
N/A |
INTRINSIC |
|
low complexity region
|
592 |
602 |
N/A |
INTRINSIC |
|
low complexity region
|
768 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1003 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy8 |
C |
T |
15: 64,576,554 (GRCm39) |
V1003I |
possibly damaging |
Het |
| Adgra3 |
T |
A |
5: 50,118,731 (GRCm39) |
Y939F |
probably benign |
Het |
| Adra2b |
T |
C |
2: 127,205,504 (GRCm39) |
V2A |
probably benign |
Het |
| Aga |
T |
A |
8: 53,974,164 (GRCm39) |
Y296N |
possibly damaging |
Het |
| Apc |
A |
G |
18: 34,401,370 (GRCm39) |
Q52R |
probably damaging |
Het |
| Arfgef1 |
A |
T |
1: 10,270,062 (GRCm39) |
S362R |
probably benign |
Het |
| Arhgef7 |
C |
T |
8: 11,808,451 (GRCm39) |
|
probably benign |
Het |
| Bmp5 |
A |
T |
9: 75,805,835 (GRCm39) |
M446L |
probably damaging |
Het |
| Carmil3 |
C |
T |
14: 55,733,534 (GRCm39) |
T350I |
probably damaging |
Het |
| Cd44 |
T |
A |
2: 102,683,363 (GRCm39) |
T224S |
probably damaging |
Het |
| Cep112 |
A |
T |
11: 108,643,260 (GRCm39) |
I7F |
possibly damaging |
Het |
| Chrna2 |
G |
A |
14: 66,379,681 (GRCm39) |
A7T |
probably benign |
Het |
| Cldn16 |
G |
A |
16: 26,301,270 (GRCm39) |
V193I |
probably benign |
Het |
| Clec4a3 |
G |
A |
6: 122,943,479 (GRCm39) |
E100K |
possibly damaging |
Het |
| Cntln |
C |
T |
4: 84,986,110 (GRCm39) |
T1026I |
possibly damaging |
Het |
| Cyp4v3 |
T |
A |
8: 45,761,564 (GRCm39) |
I420F |
probably benign |
Het |
| Dcbld2 |
G |
A |
16: 58,271,125 (GRCm39) |
A301T |
|
Het |
| Dnah1 |
A |
T |
14: 31,007,950 (GRCm39) |
D2152E |
probably benign |
Het |
| Dpy19l4 |
A |
G |
4: 11,290,195 (GRCm39) |
V179A |
probably benign |
Het |
| Dusp4 |
T |
A |
8: 35,284,462 (GRCm39) |
I259N |
probably damaging |
Het |
| Enpp1 |
T |
A |
10: 24,544,926 (GRCm39) |
I318F |
probably benign |
Het |
| Entpd6 |
T |
C |
2: 150,595,005 (GRCm39) |
V15A |
possibly damaging |
Het |
| Epb41l1 |
C |
G |
2: 156,363,923 (GRCm39) |
Q811E |
probably benign |
Het |
| Epb41l5 |
T |
C |
1: 119,570,292 (GRCm39) |
H32R |
probably damaging |
Het |
| Fam135b |
C |
T |
15: 71,334,063 (GRCm39) |
V1044I |
possibly damaging |
Het |
| Fat4 |
A |
T |
3: 39,037,778 (GRCm39) |
H3810L |
probably benign |
Het |
| Fbxw28 |
T |
A |
9: 109,167,857 (GRCm39) |
|
probably null |
Het |
| Flnb |
T |
G |
14: 7,892,874 (GRCm38) |
V648G |
probably damaging |
Het |
| Flnb |
T |
A |
14: 7,904,688 (GRCm38) |
Y1030* |
probably null |
Het |
| Fndc3a |
T |
C |
14: 72,794,410 (GRCm39) |
T787A |
probably benign |
Het |
| Gli2 |
T |
A |
1: 118,783,187 (GRCm39) |
H106L |
probably damaging |
Het |
| Gm10283 |
T |
A |
8: 60,954,390 (GRCm39) |
|
probably null |
Het |
| Gm3336 |
C |
T |
8: 71,174,545 (GRCm39) |
R67* |
probably null |
Het |
| Gsr |
T |
G |
8: 34,183,936 (GRCm39) |
I399M |
possibly damaging |
Het |
| Gtf2ird2 |
T |
A |
5: 134,245,596 (GRCm39) |
M618K |
probably damaging |
Het |
| Gtf3c3 |
T |
A |
1: 54,462,722 (GRCm39) |
D347V |
probably benign |
Het |
| Hspa12a |
T |
C |
19: 58,788,058 (GRCm39) |
Y588C |
probably damaging |
Het |
| Il20ra |
A |
G |
10: 19,635,160 (GRCm39) |
E467G |
possibly damaging |
Het |
| Inf2 |
A |
G |
12: 112,576,998 (GRCm39) |
I991V |
unknown |
Het |
| Irag2 |
A |
T |
6: 145,117,390 (GRCm39) |
M376L |
probably benign |
Het |
| Irx6 |
T |
C |
8: 93,405,040 (GRCm39) |
C303R |
probably damaging |
Het |
| Kcnmb4 |
T |
A |
10: 116,309,381 (GRCm39) |
K16* |
probably null |
Het |
| Kirrel3 |
T |
C |
9: 34,855,738 (GRCm39) |
L86P |
probably damaging |
Het |
| Lipo5 |
A |
C |
19: 33,450,530 (GRCm39) |
F21V |
|
Het |
| Lrrc31 |
T |
A |
3: 30,733,267 (GRCm39) |
R482S |
probably benign |
Het |
| Lrrc3b |
C |
T |
14: 15,358,159 (GRCm38) |
C149Y |
probably damaging |
Het |
| Lrrk1 |
A |
G |
7: 65,919,573 (GRCm39) |
M446T |
probably benign |
Het |
| Macroh2a2 |
A |
T |
10: 61,593,610 (GRCm39) |
I22N |
probably damaging |
Het |
| Mettl14 |
C |
T |
3: 123,167,693 (GRCm39) |
D222N |
probably benign |
Het |
| Mfsd4b3-ps |
G |
A |
10: 39,824,072 (GRCm39) |
H63Y |
probably benign |
Het |
| Myo16 |
T |
C |
8: 10,426,175 (GRCm39) |
W311R |
probably damaging |
Het |
| Nccrp1 |
A |
T |
7: 28,245,628 (GRCm39) |
N151K |
probably benign |
Het |
| Obsl1 |
T |
C |
1: 75,480,493 (GRCm39) |
D377G |
probably damaging |
Het |
| Or5b97 |
T |
A |
19: 12,878,578 (GRCm39) |
T189S |
probably benign |
Het |
| Or5p80 |
T |
A |
7: 108,229,506 (GRCm39) |
C102* |
probably null |
Het |
| Or7c19 |
T |
A |
8: 85,957,913 (GRCm39) |
I263N |
probably benign |
Het |
| Or7c70 |
G |
T |
10: 78,683,576 (GRCm39) |
P58T |
probably damaging |
Het |
| Pigb |
T |
C |
9: 72,945,983 (GRCm39) |
N63S |
probably damaging |
Het |
| Plch2 |
T |
C |
4: 155,077,023 (GRCm39) |
E577G |
probably benign |
Het |
| Prkab2 |
T |
C |
3: 97,573,943 (GRCm39) |
V194A |
probably benign |
Het |
| Psd3 |
T |
C |
8: 68,416,461 (GRCm39) |
I479V |
probably benign |
Het |
| Rpap2 |
T |
A |
5: 107,768,361 (GRCm39) |
S400T |
possibly damaging |
Het |
| Rpgrip1l |
C |
A |
8: 92,007,456 (GRCm39) |
W378L |
possibly damaging |
Het |
| Rps20 |
T |
A |
4: 3,834,617 (GRCm39) |
M82L |
probably benign |
Het |
| Rps5 |
T |
C |
7: 12,659,440 (GRCm39) |
M77T |
possibly damaging |
Het |
| Scaf11 |
A |
G |
15: 96,318,371 (GRCm39) |
S398P |
probably damaging |
Het |
| Sdf2 |
T |
A |
11: 78,145,763 (GRCm39) |
D153E |
probably benign |
Het |
| Selplg |
GTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCT |
GTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCT |
5: 113,957,756 (GRCm39) |
|
probably benign |
Het |
| Slc12a9 |
T |
C |
5: 137,329,270 (GRCm39) |
N128S |
probably damaging |
Het |
| Slc25a32 |
C |
A |
15: 38,960,946 (GRCm39) |
G246C |
probably damaging |
Het |
| Slc38a4 |
C |
T |
15: 96,914,662 (GRCm39) |
A64T |
probably benign |
Het |
| Slit3 |
T |
C |
11: 35,589,207 (GRCm39) |
V1254A |
probably damaging |
Het |
| Slx4 |
T |
C |
16: 3,808,111 (GRCm39) |
K481R |
probably benign |
Het |
| Tcea1 |
A |
G |
1: 4,959,732 (GRCm39) |
T136A |
probably benign |
Het |
| Thra |
A |
G |
11: 98,644,449 (GRCm39) |
D13G |
possibly damaging |
Het |
| Tmed9 |
G |
A |
13: 55,744,775 (GRCm39) |
S227N |
probably benign |
Het |
| Trim80 |
C |
A |
11: 115,331,538 (GRCm39) |
T20K |
probably benign |
Het |
| Trmt61a |
G |
T |
12: 111,649,256 (GRCm39) |
V276L |
probably benign |
Het |
| Trpc4ap |
T |
C |
2: 155,508,171 (GRCm39) |
D160G |
possibly damaging |
Het |
| Ubr5 |
C |
T |
15: 38,029,825 (GRCm39) |
E467K |
|
Het |
| Vars2 |
C |
A |
17: 35,972,541 (GRCm39) |
G26W |
probably damaging |
Het |
| Vmn1r226 |
G |
T |
17: 20,908,287 (GRCm39) |
R173L |
possibly damaging |
Het |
| Vmn1r29 |
G |
T |
6: 58,284,284 (GRCm39) |
M1I |
probably null |
Het |
| Vmn2r3 |
G |
T |
3: 64,168,803 (GRCm39) |
P578Q |
possibly damaging |
Het |
| Vmn2r57 |
A |
T |
7: 41,049,571 (GRCm39) |
I726N |
possibly damaging |
Het |
| Zfp39 |
A |
T |
11: 58,780,946 (GRCm39) |
Y605* |
probably null |
Het |
|
| Other mutations in Ralgapb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00094:Ralgapb
|
APN |
2 |
158,262,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00534:Ralgapb
|
APN |
2 |
158,272,420 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01362:Ralgapb
|
APN |
2 |
158,277,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01653:Ralgapb
|
APN |
2 |
158,304,079 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01704:Ralgapb
|
APN |
2 |
158,262,795 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Ralgapb
|
APN |
2 |
158,296,034 (GRCm39) |
splice site |
probably benign |
|
|
IGL02169:Ralgapb
|
APN |
2 |
158,268,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02516:Ralgapb
|
APN |
2 |
158,307,735 (GRCm39) |
splice site |
probably benign |
|
|
IGL02548:Ralgapb
|
APN |
2 |
158,286,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02550:Ralgapb
|
APN |
2 |
158,290,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02653:Ralgapb
|
APN |
2 |
158,285,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02744:Ralgapb
|
APN |
2 |
158,288,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Ralgapb
|
APN |
2 |
158,268,204 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02937:Ralgapb
|
APN |
2 |
158,334,936 (GRCm39) |
splice site |
probably null |
|
|
IGL02993:Ralgapb
|
APN |
2 |
158,279,314 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03154:Ralgapb
|
APN |
2 |
158,274,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Ralgapb
|
APN |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL03347:Ralgapb
|
APN |
2 |
158,307,880 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Chacha
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Gato
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Kibble
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ralston
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ralgapb
|
UTSW |
2 |
158,272,342 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0077:Ralgapb
|
UTSW |
2 |
158,315,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0581:Ralgapb
|
UTSW |
2 |
158,334,881 (GRCm39) |
missense |
probably benign |
|
|
R0629:Ralgapb
|
UTSW |
2 |
158,281,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0839:Ralgapb
|
UTSW |
2 |
158,315,203 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1331:Ralgapb
|
UTSW |
2 |
158,272,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1540:Ralgapb
|
UTSW |
2 |
158,307,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1572:Ralgapb
|
UTSW |
2 |
158,288,119 (GRCm39) |
splice site |
probably benign |
|
|
R1628:Ralgapb
|
UTSW |
2 |
158,272,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1718:Ralgapb
|
UTSW |
2 |
158,285,200 (GRCm39) |
nonsense |
probably null |
|
|
R1777:Ralgapb
|
UTSW |
2 |
158,304,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1822:Ralgapb
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1903:Ralgapb
|
UTSW |
2 |
158,337,483 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1909:Ralgapb
|
UTSW |
2 |
158,286,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2157:Ralgapb
|
UTSW |
2 |
158,279,392 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4524:Ralgapb
|
UTSW |
2 |
158,279,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4946:Ralgapb
|
UTSW |
2 |
158,282,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Ralgapb
|
UTSW |
2 |
158,277,428 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5014:Ralgapb
|
UTSW |
2 |
158,337,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5165:Ralgapb
|
UTSW |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5465:Ralgapb
|
UTSW |
2 |
158,290,325 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5526:Ralgapb
|
UTSW |
2 |
158,274,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Ralgapb
|
UTSW |
2 |
158,336,630 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5949:Ralgapb
|
UTSW |
2 |
158,296,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6140:Ralgapb
|
UTSW |
2 |
158,298,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Ralgapb
|
UTSW |
2 |
158,288,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6192:Ralgapb
|
UTSW |
2 |
158,291,367 (GRCm39) |
splice site |
probably null |
|
|
R6364:Ralgapb
|
UTSW |
2 |
158,304,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6458:Ralgapb
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6746:Ralgapb
|
UTSW |
2 |
158,318,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6788:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7017:Ralgapb
|
UTSW |
2 |
158,290,257 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,336,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,334,380 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7236:Ralgapb
|
UTSW |
2 |
158,282,747 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7454:Ralgapb
|
UTSW |
2 |
158,274,822 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7485:Ralgapb
|
UTSW |
2 |
158,285,275 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7595:Ralgapb
|
UTSW |
2 |
158,268,085 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7615:Ralgapb
|
UTSW |
2 |
158,292,190 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7728:Ralgapb
|
UTSW |
2 |
158,324,423 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7913:Ralgapb
|
UTSW |
2 |
158,307,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7953:Ralgapb
|
UTSW |
2 |
158,307,803 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8245:Ralgapb
|
UTSW |
2 |
158,285,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8337:Ralgapb
|
UTSW |
2 |
158,292,192 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8363:Ralgapb
|
UTSW |
2 |
158,268,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Ralgapb
|
UTSW |
2 |
158,268,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Ralgapb
|
UTSW |
2 |
158,292,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,279,264 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8992:Ralgapb
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9013:Ralgapb
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9141:Ralgapb
|
UTSW |
2 |
158,262,811 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9166:Ralgapb
|
UTSW |
2 |
158,274,842 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9242:Ralgapb
|
UTSW |
2 |
158,277,386 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9274:Ralgapb
|
UTSW |
2 |
158,278,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9354:Ralgapb
|
UTSW |
2 |
158,279,313 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9454:Ralgapb
|
UTSW |
2 |
158,315,072 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9489:Ralgapb
|
UTSW |
2 |
158,268,283 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9490:Ralgapb
|
UTSW |
2 |
158,334,350 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9510:Ralgapb
|
UTSW |
2 |
158,285,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Ralgapb
|
UTSW |
2 |
158,277,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAGGAAAACTGTTGTTCTGGAGC -3'
(R):5'- TGCAGTTCTTGAGTCCAACC -3'
Sequencing Primer
(F):5'- AGAGCTGCCTTGACTCTGGTC -3'
(R):5'- AGTTCTTGAGTCCAACCTCCTGG -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation