Incidental Mutation 'R8960:Insrr'
| ID |
682262 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Insrr
|
| Ensembl Gene |
ENSMUSG00000005640 |
| Gene Name |
insulin receptor-related receptor |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.285)
|
| Stock # |
R8960 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87704258-87723408 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 87720386 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 1008
(T1008K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103208
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029711]
[ENSMUST00000029714]
[ENSMUST00000090981]
[ENSMUST00000107582]
|
| AlphaFold |
Q9WTL4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029711
AA Change: T1008K
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000029711
Gene: ENSMUSG00000005640
AA Change: T1008K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
1.8e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
3.8e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029714
|
| SMART Domains |
Protein: ENSMUSP00000029714
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000090981
|
| SMART Domains |
Protein: ENSMUSP00000088503
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107582
AA Change: T1008K
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000103208
Gene: ENSMUSG00000005640
AA Change: T1008K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
7.7e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
1.6e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.9%
- 20x: 99.7%
|
| Validation Efficiency |
100% (78/78) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no anomalies in pancreatic islet morphology, beta-cell mass or pancreatic secretory function. This mutation in combination with Insr mutant mice does not affect the diabetes predisposition of Insr mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg4 |
G |
A |
9: 44,186,063 (GRCm39) |
Q603* |
probably null |
Het |
| Adar |
A |
G |
3: 89,647,516 (GRCm39) |
Y165C |
probably damaging |
Het |
| Afp |
A |
G |
5: 90,651,500 (GRCm39) |
T372A |
probably benign |
Het |
| Asah1 |
T |
A |
8: 41,800,061 (GRCm39) |
L184F |
probably damaging |
Het |
| Bltp1 |
A |
G |
3: 37,067,132 (GRCm39) |
E3548G |
probably damaging |
Het |
| Bpifb2 |
A |
T |
2: 153,731,046 (GRCm39) |
I206F |
possibly damaging |
Het |
| Btn1a1 |
C |
A |
13: 23,648,741 (GRCm39) |
D31Y |
possibly damaging |
Het |
| C4b |
T |
A |
17: 34,952,892 (GRCm39) |
D1110V |
probably damaging |
Het |
| Ccdc162 |
T |
A |
10: 41,429,178 (GRCm39) |
D1901V |
probably damaging |
Het |
| Cd101 |
A |
G |
3: 100,910,817 (GRCm39) |
V947A |
probably benign |
Het |
| Cd55b |
A |
T |
1: 130,338,375 (GRCm39) |
S238T |
possibly damaging |
Het |
| Cdc25c |
T |
C |
18: 34,866,329 (GRCm39) |
I437V |
possibly damaging |
Het |
| Cfap97 |
T |
C |
8: 46,623,605 (GRCm39) |
S332P |
probably damaging |
Het |
| Chpf |
A |
G |
1: 75,452,398 (GRCm39) |
L352P |
probably damaging |
Het |
| Cntln |
T |
A |
4: 85,018,961 (GRCm39) |
M1217K |
possibly damaging |
Het |
| Cntrl |
A |
G |
2: 35,052,053 (GRCm39) |
E1629G |
possibly damaging |
Het |
| Csnk1g2 |
T |
C |
10: 80,474,396 (GRCm39) |
Y206H |
probably damaging |
Het |
| Cyp2c55 |
T |
A |
19: 38,995,547 (GRCm39) |
W20R |
probably null |
Het |
| Dhx35 |
A |
T |
2: 158,657,393 (GRCm39) |
H130L |
possibly damaging |
Het |
| Dnm1 |
A |
G |
2: 32,202,741 (GRCm39) |
V54A |
probably damaging |
Het |
| Eea1 |
T |
A |
10: 95,864,381 (GRCm39) |
S967T |
probably benign |
Het |
| Efcab3 |
A |
G |
11: 104,820,772 (GRCm39) |
|
probably benign |
Het |
| Elf3 |
A |
T |
1: 135,182,813 (GRCm39) |
I304N |
probably damaging |
Het |
| Eps8l1 |
G |
T |
7: 4,481,214 (GRCm39) |
R672L |
probably damaging |
Het |
| Fam163a |
A |
T |
1: 155,954,862 (GRCm39) |
C96* |
probably null |
Het |
| Fancd2 |
T |
C |
6: 113,540,129 (GRCm39) |
|
probably null |
Het |
| Fbxo3 |
C |
T |
2: 103,858,274 (GRCm39) |
L23F |
possibly damaging |
Het |
| Fbxw14 |
A |
G |
9: 109,114,367 (GRCm39) |
V121A |
possibly damaging |
Het |
| Fgd6 |
T |
A |
10: 93,880,868 (GRCm39) |
V574D |
probably benign |
Het |
| Gask1b |
T |
C |
3: 79,794,293 (GRCm39) |
S254P |
probably benign |
Het |
| Gbp11 |
A |
G |
5: 105,479,251 (GRCm39) |
F124S |
probably damaging |
Het |
| Grin1 |
A |
T |
2: 25,195,428 (GRCm39) |
|
probably benign |
Het |
| Grm2 |
T |
G |
9: 106,531,345 (GRCm39) |
E48A |
probably benign |
Het |
| H2-M10.5 |
T |
A |
17: 37,084,770 (GRCm39) |
Y165N |
probably benign |
Het |
| Hoxa13 |
A |
C |
6: 52,236,976 (GRCm39) |
S172A |
probably benign |
Het |
| Ifih1 |
T |
A |
2: 62,442,235 (GRCm39) |
K376N |
possibly damaging |
Het |
| Itih1 |
A |
G |
14: 30,655,414 (GRCm39) |
S594P |
probably damaging |
Het |
| Kidins220 |
T |
C |
12: 25,106,914 (GRCm39) |
S1365P |
probably benign |
Het |
| Malrd1 |
A |
T |
2: 15,570,241 (GRCm39) |
K158* |
probably null |
Het |
| Man2c1 |
G |
A |
9: 57,045,279 (GRCm39) |
G504R |
probably damaging |
Het |
| Mbd1 |
T |
C |
18: 74,406,890 (GRCm39) |
|
probably null |
Het |
| Micall2 |
G |
A |
5: 139,702,025 (GRCm39) |
A323V |
probably benign |
Het |
| Mroh9 |
A |
C |
1: 162,883,196 (GRCm39) |
F428V |
probably benign |
Het |
| Myo7b |
T |
A |
18: 32,127,299 (GRCm39) |
|
probably benign |
Het |
| Niban1 |
A |
T |
1: 151,591,463 (GRCm39) |
H535L |
possibly damaging |
Het |
| Obscn |
A |
T |
11: 58,922,438 (GRCm39) |
V6567E |
probably damaging |
Het |
| Or1e28-ps1 |
A |
C |
11: 73,615,230 (GRCm39) |
S207A |
unknown |
Het |
| Or1e33 |
A |
T |
11: 73,738,167 (GRCm39) |
C261* |
probably null |
Het |
| Or2g25 |
T |
A |
17: 37,970,760 (GRCm39) |
T155S |
probably benign |
Het |
| Or2y1d |
A |
T |
11: 49,321,543 (GRCm39) |
Q80L |
probably benign |
Het |
| Or5h25 |
T |
A |
16: 58,930,555 (GRCm39) |
R139S |
probably benign |
Het |
| Or8b53 |
A |
T |
9: 38,667,385 (GRCm39) |
I134F |
possibly damaging |
Het |
| Pde4dip |
T |
C |
3: 97,700,464 (GRCm39) |
D238G |
probably damaging |
Het |
| Peg10 |
GAT |
GATCAT |
6: 4,756,449 (GRCm39) |
|
probably benign |
Het |
| Pgbd5 |
T |
A |
8: 125,111,175 (GRCm39) |
Y172F |
probably benign |
Het |
| Pkd1 |
A |
G |
17: 24,795,176 (GRCm39) |
T2288A |
probably damaging |
Het |
| Ppp6r2 |
T |
A |
15: 89,137,239 (GRCm39) |
M1K |
probably null |
Het |
| Rc3h1 |
A |
G |
1: 160,774,164 (GRCm39) |
T344A |
probably damaging |
Het |
| Rgs5 |
T |
C |
1: 169,504,461 (GRCm39) |
V37A |
possibly damaging |
Het |
| Rgs9 |
A |
G |
11: 109,139,815 (GRCm39) |
S17P |
possibly damaging |
Het |
| Rusc1 |
T |
A |
3: 88,991,865 (GRCm39) |
D407V |
probably damaging |
Het |
| Rwdd1 |
T |
A |
10: 33,895,383 (GRCm39) |
I18F |
possibly damaging |
Het |
| Satb2 |
C |
T |
1: 56,910,470 (GRCm39) |
|
probably null |
Het |
| Sds |
A |
G |
5: 120,621,659 (GRCm39) |
E267G |
probably damaging |
Het |
| Sema4b |
T |
A |
7: 79,875,076 (GRCm39) |
V822E |
probably damaging |
Het |
| Sfxn5 |
A |
T |
6: 85,266,176 (GRCm39) |
M107K |
probably damaging |
Het |
| Slc5a8 |
C |
T |
10: 88,722,035 (GRCm39) |
|
probably benign |
Het |
| Sorbs1 |
T |
C |
19: 40,387,048 (GRCm39) |
D6G |
probably damaging |
Het |
| Syt14 |
A |
C |
1: 192,666,515 (GRCm39) |
|
probably benign |
Het |
| Vmn2r124 |
T |
G |
17: 18,283,291 (GRCm39) |
Y328* |
probably null |
Het |
| Vmn2r86 |
T |
A |
10: 130,289,672 (GRCm39) |
E74D |
probably benign |
Het |
| Vmo1 |
A |
C |
11: 70,404,476 (GRCm39) |
L175W |
probably damaging |
Het |
| Vps13a |
G |
T |
19: 16,683,247 (GRCm39) |
L982I |
possibly damaging |
Het |
| Wdr19 |
T |
C |
5: 65,398,211 (GRCm39) |
V812A |
probably benign |
Het |
| Wdr27 |
T |
C |
17: 15,103,908 (GRCm39) |
I733V |
probably benign |
Het |
| Wdr54 |
A |
T |
6: 83,132,739 (GRCm39) |
H38Q |
probably damaging |
Het |
| Wdr76 |
G |
A |
2: 121,341,104 (GRCm39) |
V50I |
probably damaging |
Het |
| Zfp930 |
T |
A |
8: 69,680,541 (GRCm39) |
N59K |
probably damaging |
Het |
| Zfyve9 |
T |
C |
4: 108,501,558 (GRCm39) |
N1218S |
possibly damaging |
Het |
|
| Other mutations in Insrr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00718:Insrr
|
APN |
3 |
87,720,981 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00801:Insrr
|
APN |
3 |
87,721,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Insrr
|
APN |
3 |
87,708,099 (GRCm39) |
nonsense |
probably null |
|
|
IGL01755:Insrr
|
APN |
3 |
87,721,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02100:Insrr
|
APN |
3 |
87,718,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02261:Insrr
|
APN |
3 |
87,708,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Insrr
|
APN |
3 |
87,717,216 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02387:Insrr
|
APN |
3 |
87,720,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02478:Insrr
|
APN |
3 |
87,716,719 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02550:Insrr
|
APN |
3 |
87,711,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02555:Insrr
|
APN |
3 |
87,721,124 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02673:Insrr
|
APN |
3 |
87,720,368 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02724:Insrr
|
APN |
3 |
87,716,879 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02798:Insrr
|
APN |
3 |
87,717,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02969:Insrr
|
APN |
3 |
87,721,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL03073:Insrr
|
APN |
3 |
87,717,245 (GRCm39) |
splice site |
probably benign |
|
|
IGL03178:Insrr
|
APN |
3 |
87,709,848 (GRCm39) |
splice site |
probably null |
|
|
IGL03389:Insrr
|
APN |
3 |
87,716,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Insrr
|
APN |
3 |
87,716,638 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL02799:Insrr
|
UTSW |
3 |
87,720,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Insrr
|
UTSW |
3 |
87,716,923 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0357:Insrr
|
UTSW |
3 |
87,715,953 (GRCm39) |
splice site |
probably null |
|
|
R0501:Insrr
|
UTSW |
3 |
87,717,991 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0504:Insrr
|
UTSW |
3 |
87,720,463 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0522:Insrr
|
UTSW |
3 |
87,708,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Insrr
|
UTSW |
3 |
87,721,744 (GRCm39) |
splice site |
probably benign |
|
|
R0558:Insrr
|
UTSW |
3 |
87,718,288 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0599:Insrr
|
UTSW |
3 |
87,720,440 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1312:Insrr
|
UTSW |
3 |
87,707,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Insrr
|
UTSW |
3 |
87,711,369 (GRCm39) |
missense |
probably benign |
|
|
R1785:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1786:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1892:Insrr
|
UTSW |
3 |
87,721,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Insrr
|
UTSW |
3 |
87,721,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2080:Insrr
|
UTSW |
3 |
87,721,598 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2094:Insrr
|
UTSW |
3 |
87,710,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2130:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2131:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2133:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2220:Insrr
|
UTSW |
3 |
87,716,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2259:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2404:Insrr
|
UTSW |
3 |
87,709,974 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4027:Insrr
|
UTSW |
3 |
87,716,906 (GRCm39) |
missense |
probably benign |
|
|
R4042:Insrr
|
UTSW |
3 |
87,721,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4511:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4571:Insrr
|
UTSW |
3 |
87,708,194 (GRCm39) |
missense |
probably benign |
|
|
R4870:Insrr
|
UTSW |
3 |
87,718,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Insrr
|
UTSW |
3 |
87,722,572 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5393:Insrr
|
UTSW |
3 |
87,718,007 (GRCm39) |
splice site |
probably null |
|
|
R5685:Insrr
|
UTSW |
3 |
87,707,803 (GRCm39) |
splice site |
probably null |
|
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6047:Insrr
|
UTSW |
3 |
87,711,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6276:Insrr
|
UTSW |
3 |
87,707,826 (GRCm39) |
nonsense |
probably null |
|
|
R6298:Insrr
|
UTSW |
3 |
87,720,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6726:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6727:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6728:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6796:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7041:Insrr
|
UTSW |
3 |
87,722,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7169:Insrr
|
UTSW |
3 |
87,715,901 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7270:Insrr
|
UTSW |
3 |
87,710,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Insrr
|
UTSW |
3 |
87,721,623 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7398:Insrr
|
UTSW |
3 |
87,716,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7473:Insrr
|
UTSW |
3 |
87,711,838 (GRCm39) |
splice site |
probably null |
|
|
R7815:Insrr
|
UTSW |
3 |
87,716,002 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8159:Insrr
|
UTSW |
3 |
87,707,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8289:Insrr
|
UTSW |
3 |
87,721,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8309:Insrr
|
UTSW |
3 |
87,717,749 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8312:Insrr
|
UTSW |
3 |
87,707,791 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8445:Insrr
|
UTSW |
3 |
87,720,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8917:Insrr
|
UTSW |
3 |
87,718,276 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8989:Insrr
|
UTSW |
3 |
87,722,664 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9015:Insrr
|
UTSW |
3 |
87,720,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:Insrr
|
UTSW |
3 |
87,720,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9251:Insrr
|
UTSW |
3 |
87,717,391 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9327:Insrr
|
UTSW |
3 |
87,721,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9646:Insrr
|
UTSW |
3 |
87,721,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF022:Insrr
|
UTSW |
3 |
87,711,792 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1177:Insrr
|
UTSW |
3 |
87,708,134 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
Z1192:Insrr
|
UTSW |
3 |
87,709,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATAGACGCCTTTGTCCTGCC -3'
(R):5'- TCAGGATTTTAACCACAGTCCC -3'
Sequencing Primer
(F):5'- GTGTGAGCCTGTAGTTACCAAAATC -3'
(R):5'- GTCCCAACCCTGACCTGGATAATTC -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation