Mutagenetix > Incidental Mutation

Incidental Mutation 'R8960:Peg10'

682274

Institutional Source

Beutler Lab

Gene Symbol

Peg10

Ensembl Gene

ENSMUSG00000092035

Gene Name

paternally expressed 10

Synonyms

MEF3L, MyEF-3 like, Rtl2, Mar2, MyEF-3, HB-1, Edr, Mart2

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R8960 (G1)

Quality Score

165.468

Status

Validated

Chromosome

Chromosomal Location

4747306-4760517 bp(+) (GRCm39)

Type of Mutation

small insertion (1 aa in frame mutation)

DNA Base Change (assembly)

GAT to GATCAT at 4756449 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000135076 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166678] [ENSMUST00000176204] [ENSMUST00000176551]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000166678

SMART Domains

Protein: ENSMUSP00000127306
Gene: ENSMUSG00000092035

Domain	Start	End	E-Value	Type
low complexity region	11	26	N/A	INTRINSIC
low complexity region	34	50	N/A	INTRINSIC
low complexity region	80	107	N/A	INTRINSIC
Pfam:DUF4939	130	220	6.1e-17	PFAM
Pfam:Retrotrans_gag	174	267	2.9e-20	PFAM
low complexity region	334	342	N/A	INTRINSIC
ZnF_C2HC	345	361	3.34e-2	SMART
low complexity region	368	379	N/A	INTRINSIC
low complexity region	541	610	N/A	INTRINSIC
low complexity region	621	660	N/A	INTRINSIC
low complexity region	663	785	N/A	INTRINSIC
Blast:SERPIN	798	910	1e-5	BLAST
low complexity region	923	936	N/A	INTRINSIC
low complexity region	972	998	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000176204

SMART Domains

Protein: ENSMUSP00000134963
Gene: ENSMUSG00000092035

Domain	Start	End	E-Value	Type
low complexity region	11	26	N/A	INTRINSIC
low complexity region	34	50	N/A	INTRINSIC
low complexity region	80	107	N/A	INTRINSIC
Pfam:Retrotrans_gag	174	267	1.3e-20	PFAM
low complexity region	334	342	N/A	INTRINSIC
ZnF_C2HC	345	361	3.34e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000176551

SMART Domains

Protein: ENSMUSP00000135076
Gene: ENSMUSG00000092035

Domain	Start	End	E-Value	Type
low complexity region	173	242	N/A	INTRINSIC
low complexity region	253	292	N/A	INTRINSIC
low complexity region	295	417	N/A	INTRINSIC
Blast:SERPIN	430	542	6e-6	BLAST
low complexity region	555	568	N/A	INTRINSIC
low complexity region	604	630	N/A	INTRINSIC

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.9%
20x: 99.7%

Validation Efficiency

100% (78/78)

MGI Phenotype

FUNCTION: This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation, apoptosis and cancer development. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. [provided by RefSeq, Oct 2014]
PHENOTYPE: Heterozygous mice with a paternally inherited null allele display embryonic lethality during organogenesis with abnormal placental development. Heterozygous mice with a maternally inherited null allele are viable and fertile. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 79 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcg4	G	A	9: 44,186,063 (GRCm39)	Q603*	probably null	Het
Adar	A	G	3: 89,647,516 (GRCm39)	Y165C	probably damaging	Het
Afp	A	G	5: 90,651,500 (GRCm39)	T372A	probably benign	Het
Asah1	T	A	8: 41,800,061 (GRCm39)	L184F	probably damaging	Het
Bltp1	A	G	3: 37,067,132 (GRCm39)	E3548G	probably damaging	Het
Bpifb2	A	T	2: 153,731,046 (GRCm39)	I206F	possibly damaging	Het
Btn1a1	C	A	13: 23,648,741 (GRCm39)	D31Y	possibly damaging	Het
C4b	T	A	17: 34,952,892 (GRCm39)	D1110V	probably damaging	Het
Ccdc162	T	A	10: 41,429,178 (GRCm39)	D1901V	probably damaging	Het
Cd101	A	G	3: 100,910,817 (GRCm39)	V947A	probably benign	Het
Cd55b	A	T	1: 130,338,375 (GRCm39)	S238T	possibly damaging	Het
Cdc25c	T	C	18: 34,866,329 (GRCm39)	I437V	possibly damaging	Het
Cfap97	T	C	8: 46,623,605 (GRCm39)	S332P	probably damaging	Het
Chpf	A	G	1: 75,452,398 (GRCm39)	L352P	probably damaging	Het
Cntln	T	A	4: 85,018,961 (GRCm39)	M1217K	possibly damaging	Het
Cntrl	A	G	2: 35,052,053 (GRCm39)	E1629G	possibly damaging	Het
Csnk1g2	T	C	10: 80,474,396 (GRCm39)	Y206H	probably damaging	Het
Cyp2c55	T	A	19: 38,995,547 (GRCm39)	W20R	probably null	Het
Dhx35	A	T	2: 158,657,393 (GRCm39)	H130L	possibly damaging	Het
Dnm1	A	G	2: 32,202,741 (GRCm39)	V54A	probably damaging	Het
Eea1	T	A	10: 95,864,381 (GRCm39)	S967T	probably benign	Het
Efcab3	A	G	11: 104,820,772 (GRCm39)		probably benign	Het
Elf3	A	T	1: 135,182,813 (GRCm39)	I304N	probably damaging	Het
Eps8l1	G	T	7: 4,481,214 (GRCm39)	R672L	probably damaging	Het
Fam163a	A	T	1: 155,954,862 (GRCm39)	C96*	probably null	Het
Fancd2	T	C	6: 113,540,129 (GRCm39)		probably null	Het
Fbxo3	C	T	2: 103,858,274 (GRCm39)	L23F	possibly damaging	Het
Fbxw14	A	G	9: 109,114,367 (GRCm39)	V121A	possibly damaging	Het
Fgd6	T	A	10: 93,880,868 (GRCm39)	V574D	probably benign	Het
Gask1b	T	C	3: 79,794,293 (GRCm39)	S254P	probably benign	Het
Gbp11	A	G	5: 105,479,251 (GRCm39)	F124S	probably damaging	Het
Grin1	A	T	2: 25,195,428 (GRCm39)		probably benign	Het
Grm2	T	G	9: 106,531,345 (GRCm39)	E48A	probably benign	Het
H2-M10.5	T	A	17: 37,084,770 (GRCm39)	Y165N	probably benign	Het
Hoxa13	A	C	6: 52,236,976 (GRCm39)	S172A	probably benign	Het
Ifih1	T	A	2: 62,442,235 (GRCm39)	K376N	possibly damaging	Het
Insrr	C	A	3: 87,720,386 (GRCm39)	T1008K	probably damaging	Het
Itih1	A	G	14: 30,655,414 (GRCm39)	S594P	probably damaging	Het
Kidins220	T	C	12: 25,106,914 (GRCm39)	S1365P	probably benign	Het
Malrd1	A	T	2: 15,570,241 (GRCm39)	K158*	probably null	Het
Man2c1	G	A	9: 57,045,279 (GRCm39)	G504R	probably damaging	Het
Mbd1	T	C	18: 74,406,890 (GRCm39)		probably null	Het
Micall2	G	A	5: 139,702,025 (GRCm39)	A323V	probably benign	Het
Mroh9	A	C	1: 162,883,196 (GRCm39)	F428V	probably benign	Het
Myo7b	T	A	18: 32,127,299 (GRCm39)		probably benign	Het
Niban1	A	T	1: 151,591,463 (GRCm39)	H535L	possibly damaging	Het
Obscn	A	T	11: 58,922,438 (GRCm39)	V6567E	probably damaging	Het
Or1e28-ps1	A	C	11: 73,615,230 (GRCm39)	S207A	unknown	Het
Or1e33	A	T	11: 73,738,167 (GRCm39)	C261*	probably null	Het
Or2g25	T	A	17: 37,970,760 (GRCm39)	T155S	probably benign	Het
Or2y1d	A	T	11: 49,321,543 (GRCm39)	Q80L	probably benign	Het
Or5h25	T	A	16: 58,930,555 (GRCm39)	R139S	probably benign	Het
Or8b53	A	T	9: 38,667,385 (GRCm39)	I134F	possibly damaging	Het
Pde4dip	T	C	3: 97,700,464 (GRCm39)	D238G	probably damaging	Het
Pgbd5	T	A	8: 125,111,175 (GRCm39)	Y172F	probably benign	Het
Pkd1	A	G	17: 24,795,176 (GRCm39)	T2288A	probably damaging	Het
Ppp6r2	T	A	15: 89,137,239 (GRCm39)	M1K	probably null	Het
Rc3h1	A	G	1: 160,774,164 (GRCm39)	T344A	probably damaging	Het
Rgs5	T	C	1: 169,504,461 (GRCm39)	V37A	possibly damaging	Het
Rgs9	A	G	11: 109,139,815 (GRCm39)	S17P	possibly damaging	Het
Rusc1	T	A	3: 88,991,865 (GRCm39)	D407V	probably damaging	Het
Rwdd1	T	A	10: 33,895,383 (GRCm39)	I18F	possibly damaging	Het
Satb2	C	T	1: 56,910,470 (GRCm39)		probably null	Het
Sds	A	G	5: 120,621,659 (GRCm39)	E267G	probably damaging	Het
Sema4b	T	A	7: 79,875,076 (GRCm39)	V822E	probably damaging	Het
Sfxn5	A	T	6: 85,266,176 (GRCm39)	M107K	probably damaging	Het
Slc5a8	C	T	10: 88,722,035 (GRCm39)		probably benign	Het
Sorbs1	T	C	19: 40,387,048 (GRCm39)	D6G	probably damaging	Het
Syt14	A	C	1: 192,666,515 (GRCm39)		probably benign	Het
Vmn2r124	T	G	17: 18,283,291 (GRCm39)	Y328*	probably null	Het
Vmn2r86	T	A	10: 130,289,672 (GRCm39)	E74D	probably benign	Het
Vmo1	A	C	11: 70,404,476 (GRCm39)	L175W	probably damaging	Het
Vps13a	G	T	19: 16,683,247 (GRCm39)	L982I	possibly damaging	Het
Wdr19	T	C	5: 65,398,211 (GRCm39)	V812A	probably benign	Het
Wdr27	T	C	17: 15,103,908 (GRCm39)	I733V	probably benign	Het
Wdr54	A	T	6: 83,132,739 (GRCm39)	H38Q	probably damaging	Het
Wdr76	G	A	2: 121,341,104 (GRCm39)	V50I	probably damaging	Het
Zfp930	T	A	8: 69,680,541 (GRCm39)	N59K	probably damaging	Het
Zfyve9	T	C	4: 108,501,558 (GRCm39)	N1218S	possibly damaging	Het

Other mutations in Peg10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02029:Peg10	APN	6	4,754,473 (GRCm39)	utr 5 prime	probably benign
IGL03063:Peg10	APN	6	4,756,647 (GRCm39)	utr 3 prime	probably benign
piaggio	UTSW	6	4,756,427 (GRCm39)	utr 3 prime	probably benign
PIT4480001:Peg10	UTSW	6	4,756,560 (GRCm39)	missense	unknown
R0090:Peg10	UTSW	6	4,756,063 (GRCm39)	utr 3 prime	probably benign
R0148:Peg10	UTSW	6	4,755,711 (GRCm39)	missense	possibly damaging	0.88
R0650:Peg10	UTSW	6	4,756,475 (GRCm39)	small insertion	probably benign
R0698:Peg10	UTSW	6	4,756,835 (GRCm39)	utr 3 prime	probably benign
R1600:Peg10	UTSW	6	4,757,080 (GRCm39)	utr 3 prime	probably benign
R1842:Peg10	UTSW	6	4,756,381 (GRCm39)	utr 3 prime	probably benign
R1930:Peg10	UTSW	6	4,755,778 (GRCm39)	missense	probably damaging	0.99
R1931:Peg10	UTSW	6	4,755,778 (GRCm39)	missense	probably damaging	0.99
R2162:Peg10	UTSW	6	4,755,914 (GRCm39)	utr 3 prime	probably benign
R2215:Peg10	UTSW	6	4,756,918 (GRCm39)	utr 3 prime	probably benign
R2339:Peg10	UTSW	6	4,756,102 (GRCm39)	utr 3 prime	probably benign
R2847:Peg10	UTSW	6	4,756,912 (GRCm39)	utr 3 prime	probably benign
R2848:Peg10	UTSW	6	4,756,912 (GRCm39)	utr 3 prime	probably benign
R3000:Peg10	UTSW	6	4,754,276 (GRCm39)	utr 5 prime	probably benign
R3056:Peg10	UTSW	6	4,755,029 (GRCm39)	missense	possibly damaging	0.66
R4051:Peg10	UTSW	6	4,754,534 (GRCm39)	missense	probably benign	0.00
R4059:Peg10	UTSW	6	4,756,427 (GRCm39)	utr 3 prime	probably benign
R4296:Peg10	UTSW	6	4,756,472 (GRCm39)	small insertion	probably benign
R4626:Peg10	UTSW	6	4,756,460 (GRCm39)	small insertion	probably benign
R4634:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R4679:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R4834:Peg10	UTSW	6	4,754,294 (GRCm39)	utr 5 prime	probably benign
R4982:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R4983:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R4996:Peg10	UTSW	6	4,756,454 (GRCm39)	small insertion	probably benign
R4997:Peg10	UTSW	6	4,756,457 (GRCm39)	small insertion	probably benign
R5015:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R5085:Peg10	UTSW	6	4,755,864 (GRCm39)	utr 3 prime	probably benign
R5091:Peg10	UTSW	6	4,754,511 (GRCm39)	missense	probably benign	0.01
R5231:Peg10	UTSW	6	4,756,939 (GRCm39)	utr 3 prime	probably benign
R5278:Peg10	UTSW	6	4,756,442 (GRCm39)	small deletion	probably benign
R5364:Peg10	UTSW	6	4,756,128 (GRCm39)	utr 3 prime	probably benign
R5397:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R5485:Peg10	UTSW	6	4,755,565 (GRCm39)	missense	probably benign	0.09
R5573:Peg10	UTSW	6	4,755,913 (GRCm39)	utr 3 prime	probably benign
R5710:Peg10	UTSW	6	4,756,351 (GRCm39)	small insertion	probably benign
R5710:Peg10	UTSW	6	4,756,350 (GRCm39)	small insertion	probably benign
R5736:Peg10	UTSW	6	4,754,423 (GRCm39)	missense	probably benign	0.00
R5865:Peg10	UTSW	6	4,754,375 (GRCm39)	missense	probably damaging	0.98
R6056:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6116:Peg10	UTSW	6	4,756,351 (GRCm39)	small insertion	probably benign
R6129:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6147:Peg10	UTSW	6	4,754,499 (GRCm39)	start gained	probably benign
R6171:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6194:Peg10	UTSW	6	4,756,351 (GRCm39)	small insertion	probably benign
R6197:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6207:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6215:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6276:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6281:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6287:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R6302:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6393:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6394:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R6405:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R6421:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6486:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6538:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6668:Peg10	UTSW	6	4,754,502 (GRCm39)	missense	probably benign	0.01
R6679:Peg10	UTSW	6	4,754,276 (GRCm39)	utr 5 prime	probably benign
R6685:Peg10	UTSW	6	4,754,738 (GRCm39)	missense	probably damaging	1.00
R6702:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6706:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6747:Peg10	UTSW	6	4,757,137 (GRCm39)	utr 3 prime	probably benign
R6775:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6811:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R6823:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R6826:Peg10	UTSW	6	4,756,353 (GRCm39)	small insertion	probably benign
R6847:Peg10	UTSW	6	4,754,279 (GRCm39)	utr 5 prime	probably benign
R6861:Peg10	UTSW	6	4,756,351 (GRCm39)	small insertion	probably benign
R6861:Peg10	UTSW	6	4,756,350 (GRCm39)	small insertion	probably benign
R6876:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R6891:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R6911:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R6973:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R6990:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R6998:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7070:Peg10	UTSW	6	4,756,454 (GRCm39)	small insertion	probably benign
R7120:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7132:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7140:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7189:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R7208:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7256:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7260:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7261:Peg10	UTSW	6	4,756,591 (GRCm39)	missense	unknown
R7401:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7409:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7439:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R7475:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7483:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R7502:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7515:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7520:Peg10	UTSW	6	4,756,796 (GRCm39)	missense	unknown
R7544:Peg10	UTSW	6	4,756,427 (GRCm39)	frame shift	probably null
R7571:Peg10	UTSW	6	4,756,082 (GRCm39)	missense	unknown
R7581:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7635:Peg10	UTSW	6	4,754,938 (GRCm39)	missense	probably damaging	0.99
R7677:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7697:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R7710:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7803:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R7816:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R7820:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R7827:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7861:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R7881:Peg10	UTSW	6	4,756,454 (GRCm39)	small insertion	probably benign
R7904:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R7915:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R7916:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R7963:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8016:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8037:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8062:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8081:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8113:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8115:Peg10	UTSW	6	4,756,707 (GRCm39)	missense	unknown
R8140:Peg10	UTSW	6	4,756,113 (GRCm39)	missense	unknown
R8178:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8233:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R8239:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8281:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R8310:Peg10	UTSW	6	4,756,454 (GRCm39)	small insertion	probably benign
R8312:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8330:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8338:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8354:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8387:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8390:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8408:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R8415:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8439:Peg10	UTSW	6	4,755,462 (GRCm39)	missense	possibly damaging	0.58
R8444:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8463:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R8477:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R8507:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R8552:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8678:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R8699:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8700:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8705:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8765:Peg10	UTSW	6	4,754,492 (GRCm39)	missense	unknown
R8824:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8859:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8870:Peg10	UTSW	6	4,754,825 (GRCm39)	missense	probably damaging	0.99
R8909:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R8918:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8924:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R8925:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8930:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R8950:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8975:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R8988:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9046:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9068:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9074:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9088:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R9094:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R9114:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9116:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9135:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R9137:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9139:Peg10	UTSW	6	4,757,128 (GRCm39)	missense	unknown
R9139:Peg10	UTSW	6	4,756,449 (GRCm39)	small insertion	probably benign
R9171:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9173:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9213:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9216:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9229:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9233:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9283:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9328:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9367:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9369:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9405:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9410:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9412:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R9421:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9437:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9440:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9460:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9492:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9495:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9500:Peg10	UTSW	6	4,756,871 (GRCm39)	missense	unknown
R9511:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9515:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9576:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9610:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9611:Peg10	UTSW	6	4,756,453 (GRCm39)	small insertion	probably benign
R9611:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9614:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign
R9619:Peg10	UTSW	6	4,755,316 (GRCm39)	missense	probably benign	0.02
R9646:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9655:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9673:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
R9675:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9696:Peg10	UTSW	6	4,756,431 (GRCm39)	small deletion	probably benign
R9749:Peg10	UTSW	6	4,756,398 (GRCm39)	small deletion	probably benign
R9756:Peg10	UTSW	6	4,756,452 (GRCm39)	small insertion	probably benign
X0065:Peg10	UTSW	6	4,756,515 (GRCm39)	utr 3 prime	probably benign
Z1176:Peg10	UTSW	6	4,756,451 (GRCm39)	small insertion	probably benign

Predicted Primers

PCR Primer
(F):5'- GTTTACAGTGCCACAACCG -3'
(R):5'- TACAGGGTGGTAAATTCTGAATCC -3'

Sequencing Primer
(F):5'- TCAGCATGAGCATCTGCATG -3'
(R):5'- CTGAATCCAGCCATGTGGTAG -3'

Posted On

2021-08-31