Incidental Mutation 'R8962:Adamts17'
| ID |
682392 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts17
|
| Ensembl Gene |
ENSMUSG00000058145 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 17 |
| Synonyms |
AU023434 |
| MMRRC Submission |
068796-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.081)
|
| Stock # |
R8962 (G1)
|
| Quality Score |
186.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
66489483-66802919 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 66725057 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Valine
at position 162
(L162V)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098382]
[ENSMUST00000107478]
|
| AlphaFold |
E9Q4D1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000098382
AA Change: L793V
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000095984
Gene: ENSMUSG00000058145
AA Change: L793V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
35 |
179 |
2.9e-25 |
PFAM |
|
Pfam:Reprolysin_5
|
228 |
422 |
3.1e-15 |
PFAM |
|
Pfam:Reprolysin_2
|
248 |
440 |
6.1e-13 |
PFAM |
|
Pfam:Reprolysin_3
|
252 |
398 |
2.2e-12 |
PFAM |
|
Pfam:Reprolysin_4
|
328 |
446 |
7.1e-10 |
PFAM |
|
Pfam:Reprolysin
|
334 |
450 |
2e-18 |
PFAM |
|
Blast:ACR
|
454 |
533 |
3e-12 |
BLAST |
|
TSP1
|
544 |
596 |
2.2e-15 |
SMART |
|
Pfam:ADAM_spacer1
|
698 |
808 |
6.4e-30 |
PFAM |
|
TSP1
|
829 |
887 |
1.81e-1 |
SMART |
|
TSP1
|
889 |
942 |
1.15e-4 |
SMART |
|
TSP1
|
949 |
993 |
4.05e-5 |
SMART |
|
TSP1
|
1000 |
1054 |
2.91e-6 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107478
AA Change: L766V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103102
Gene: ENSMUSG00000058145
AA Change: L766V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
34 |
180 |
3.1e-23 |
PFAM |
|
Pfam:Reprolysin_5
|
228 |
424 |
3.2e-15 |
PFAM |
|
Pfam:Reprolysin_2
|
248 |
440 |
5.9e-11 |
PFAM |
|
Pfam:Reprolysin_3
|
252 |
398 |
6e-12 |
PFAM |
|
Pfam:Reprolysin_4
|
328 |
446 |
6.8e-10 |
PFAM |
|
Pfam:Reprolysin
|
334 |
450 |
4.3e-21 |
PFAM |
|
Blast:ACR
|
454 |
533 |
3e-12 |
BLAST |
|
TSP1
|
544 |
596 |
2.2e-15 |
SMART |
|
Pfam:ADAM_spacer1
|
700 |
781 |
2.2e-16 |
PFAM |
|
TSP1
|
802 |
860 |
1.81e-1 |
SMART |
|
TSP1
|
862 |
915 |
1.15e-4 |
SMART |
|
TSP1
|
922 |
966 |
4.05e-5 |
SMART |
|
TSP1
|
973 |
1027 |
2.91e-6 |
SMART |
|
Pfam:PLAC
|
1046 |
1080 |
1.1e-10 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000154103
AA Change: L162V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000121836
Gene: ENSMUSG00000058145
AA Change: L162V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ADAM_spacer1
|
68 |
178 |
4e-31 |
PFAM |
|
Blast:TSP1
|
199 |
234 |
6e-17 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.3%
- 20x: 97.4%
|
| Validation Efficiency |
99% (86/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome, which is characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. [provided by RefSeq, May 2016]
|
| Allele List at MGI |
All alleles(3) : Targeted, other(2) Gene trapped(1) |
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
T |
A |
9: 46,220,173 (GRCm39) |
M120L |
probably benign |
Het |
| Abat |
A |
G |
16: 8,396,166 (GRCm39) |
T48A |
probably damaging |
Het |
| Abca8a |
A |
T |
11: 109,969,634 (GRCm39) |
I314N |
probably damaging |
Het |
| Abr |
A |
T |
11: 76,352,155 (GRCm39) |
V108D |
probably damaging |
Het |
| Adamts6 |
A |
T |
13: 104,433,899 (GRCm39) |
K109N |
probably damaging |
Het |
| Ago3 |
A |
G |
4: 126,241,595 (GRCm39) |
F68S |
probably damaging |
Het |
| Aifm3 |
T |
C |
16: 17,324,200 (GRCm39) |
|
probably null |
Het |
| Ankrd26 |
T |
C |
6: 118,512,104 (GRCm39) |
E506G |
probably benign |
Het |
| Apaf1 |
A |
G |
10: 90,903,066 (GRCm39) |
L185P |
probably damaging |
Het |
| Atp8b3 |
G |
T |
10: 80,355,896 (GRCm39) |
T1272K |
probably benign |
Het |
| Cars2 |
A |
G |
8: 11,587,304 (GRCm39) |
V193A |
probably benign |
Het |
| Ccn5 |
C |
T |
2: 163,667,160 (GRCm39) |
R54* |
probably null |
Het |
| Ccr8 |
A |
T |
9: 119,923,613 (GRCm39) |
I243F |
possibly damaging |
Het |
| Col12a1 |
A |
G |
9: 79,538,901 (GRCm39) |
V2465A |
probably damaging |
Het |
| Ctbp1 |
T |
C |
5: 33,416,616 (GRCm39) |
N127S |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,149,377 (GRCm39) |
S117P |
probably damaging |
Het |
| Dgkb |
T |
C |
12: 38,189,494 (GRCm39) |
|
probably null |
Het |
| Dnah11 |
T |
A |
12: 117,916,273 (GRCm39) |
D3520V |
probably damaging |
Het |
| Dnah11 |
C |
T |
12: 117,918,630 (GRCm39) |
D1530N |
probably damaging |
Het |
| Dock5 |
T |
C |
14: 67,994,640 (GRCm39) |
T1807A |
probably benign |
Het |
| Drd3 |
C |
T |
16: 43,641,842 (GRCm39) |
T386I |
probably damaging |
Het |
| Dsg1b |
A |
G |
18: 20,542,316 (GRCm39) |
N941S |
probably damaging |
Het |
| Enpp3 |
T |
C |
10: 24,696,513 (GRCm39) |
T141A |
probably benign |
Het |
| Esyt1 |
A |
T |
10: 128,356,566 (GRCm39) |
C360S |
possibly damaging |
Het |
| Ethe1 |
T |
A |
7: 24,305,682 (GRCm39) |
V143D |
probably damaging |
Het |
| Fam170b |
A |
G |
14: 32,557,336 (GRCm39) |
D57G |
probably benign |
Het |
| Fam53c |
T |
C |
18: 34,901,229 (GRCm39) |
S49P |
probably damaging |
Het |
| Fbp1 |
G |
A |
13: 63,023,067 (GRCm39) |
L77F |
probably benign |
Het |
| Gm17093 |
A |
G |
14: 44,758,149 (GRCm39) |
E110G |
|
Het |
| Gm21976 |
G |
T |
13: 98,423,821 (GRCm39) |
|
silent |
Het |
| Golgb1 |
T |
C |
16: 36,733,978 (GRCm39) |
I1075T |
probably damaging |
Het |
| Grip2 |
T |
C |
6: 91,754,391 (GRCm39) |
D628G |
probably damaging |
Het |
| Gtpbp1 |
G |
T |
15: 79,601,929 (GRCm39) |
L557F |
probably benign |
Het |
| Ighv12-3 |
A |
T |
12: 114,330,204 (GRCm39) |
F97Y |
probably benign |
Het |
| Itga8 |
T |
C |
2: 12,196,045 (GRCm39) |
H635R |
possibly damaging |
Het |
| Itgb7 |
A |
G |
15: 102,127,037 (GRCm39) |
L466S |
probably damaging |
Het |
| Klc2 |
T |
C |
19: 5,161,864 (GRCm39) |
D277G |
probably benign |
Het |
| Ktn1 |
A |
G |
14: 47,901,248 (GRCm39) |
E2G |
probably damaging |
Het |
| Lcmt1 |
T |
A |
7: 123,000,669 (GRCm39) |
Y68N |
probably damaging |
Het |
| Marchf10 |
G |
T |
11: 105,280,815 (GRCm39) |
S490* |
probably null |
Het |
| Mterf1b |
A |
T |
5: 4,246,437 (GRCm39) |
Y26F |
probably benign |
Het |
| Myo18b |
T |
A |
5: 113,006,346 (GRCm39) |
I855F |
probably benign |
Het |
| Nek4 |
G |
A |
14: 30,675,915 (GRCm39) |
M83I |
probably damaging |
Het |
| Nicn1 |
C |
T |
9: 108,171,708 (GRCm39) |
R163C |
possibly damaging |
Het |
| Nos1 |
T |
C |
5: 118,017,405 (GRCm39) |
V256A |
probably benign |
Het |
| Nr1h2 |
T |
C |
7: 44,201,463 (GRCm39) |
T50A |
probably benign |
Het |
| Or14c42-ps1 |
T |
A |
7: 86,211,317 (GRCm39) |
*126K |
probably null |
Het |
| Or4n4 |
A |
C |
14: 50,518,816 (GRCm39) |
M298R |
possibly damaging |
Het |
| Ovol2 |
G |
C |
2: 144,147,834 (GRCm39) |
R172G |
probably damaging |
Het |
| Parp14 |
A |
G |
16: 35,677,187 (GRCm39) |
I927T |
probably damaging |
Het |
| Pcdhga7 |
T |
A |
18: 37,848,879 (GRCm39) |
H295Q |
probably benign |
Het |
| Pkhd1l1 |
C |
T |
15: 44,400,291 (GRCm39) |
T2145I |
probably damaging |
Het |
| Plekhs1 |
C |
T |
19: 56,461,680 (GRCm39) |
T139I |
possibly damaging |
Het |
| Rab11fip3 |
T |
A |
17: 26,231,007 (GRCm39) |
D746V |
probably damaging |
Het |
| Rnf214 |
A |
C |
9: 45,809,728 (GRCm39) |
|
probably null |
Het |
| Rtn4ip1 |
A |
T |
10: 43,822,415 (GRCm39) |
|
probably null |
Het |
| S1pr1 |
T |
C |
3: 115,505,569 (GRCm39) |
R342G |
|
Het |
| Serpina1f |
T |
C |
12: 103,656,131 (GRCm39) |
S366G |
probably benign |
Het |
| Sestd1 |
A |
T |
2: 77,042,708 (GRCm39) |
M282K |
probably benign |
Het |
| Siglecf |
T |
G |
7: 43,001,140 (GRCm39) |
V36G |
probably damaging |
Het |
| Slc1a1 |
T |
C |
19: 28,886,869 (GRCm39) |
V410A |
probably damaging |
Het |
| Slc38a4 |
C |
A |
15: 96,917,684 (GRCm39) |
D14Y |
probably benign |
Het |
| Slk |
C |
T |
19: 47,610,748 (GRCm39) |
T806M |
probably damaging |
Het |
| Slurp2 |
C |
A |
15: 74,615,249 (GRCm39) |
V48F |
possibly damaging |
Het |
| Socs1 |
A |
G |
16: 10,602,642 (GRCm39) |
S32P |
possibly damaging |
Het |
| Son |
T |
C |
16: 91,455,057 (GRCm39) |
V1268A |
possibly damaging |
Het |
| Sp7 |
C |
A |
15: 102,274,880 (GRCm39) |
|
probably benign |
Het |
| Speer4a2 |
T |
G |
5: 26,290,745 (GRCm39) |
E142A |
probably benign |
Het |
| Taar7b |
T |
G |
10: 23,876,359 (GRCm39) |
S175A |
probably benign |
Het |
| Tet2 |
T |
C |
3: 133,193,804 (GRCm39) |
N210S |
probably benign |
Het |
| Tkfc |
T |
C |
19: 10,570,700 (GRCm39) |
D492G |
probably damaging |
Het |
| Tmc7 |
G |
A |
7: 118,160,228 (GRCm39) |
P203L |
probably benign |
Het |
| Trmt9b |
A |
G |
8: 36,972,729 (GRCm39) |
K60E |
probably damaging |
Het |
| Tshz2 |
C |
A |
2: 169,726,524 (GRCm39) |
F373L |
probably damaging |
Het |
| Ttc29 |
T |
A |
8: 79,042,336 (GRCm39) |
L307Q |
probably damaging |
Het |
| Tubd1 |
G |
A |
11: 86,439,659 (GRCm39) |
M1I |
probably null |
Het |
| Vmn1r62 |
T |
A |
7: 5,678,601 (GRCm39) |
M94K |
probably damaging |
Het |
| Vmn2r125 |
T |
C |
4: 156,703,186 (GRCm39) |
I188T |
possibly damaging |
Het |
| Vmn2r5 |
T |
C |
3: 64,398,564 (GRCm39) |
D805G |
probably damaging |
Het |
| Vmn2r6 |
A |
T |
3: 64,463,576 (GRCm39) |
D419E |
probably damaging |
Het |
| Vps39 |
A |
T |
2: 120,174,687 (GRCm39) |
Y98* |
probably null |
Het |
| Zdbf2 |
G |
A |
1: 63,347,162 (GRCm39) |
G1847D |
probably benign |
Het |
| Zdhhc6 |
T |
C |
19: 55,287,239 (GRCm39) |
E407G |
probably benign |
Het |
| Zfp407 |
A |
G |
18: 84,577,057 (GRCm39) |
I1352T |
probably damaging |
Het |
| Zfp607a |
A |
G |
7: 27,578,786 (GRCm39) |
K619E |
possibly damaging |
Het |
| Zfp811 |
A |
T |
17: 33,017,622 (GRCm39) |
N139K |
probably benign |
Het |
|
| Other mutations in Adamts17 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00708:Adamts17
|
APN |
7 |
66,618,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00950:Adamts17
|
APN |
7 |
66,770,660 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01532:Adamts17
|
APN |
7 |
66,558,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01591:Adamts17
|
APN |
7 |
66,654,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01602:Adamts17
|
APN |
7 |
66,538,159 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL01640:Adamts17
|
APN |
7 |
66,679,428 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01686:Adamts17
|
APN |
7 |
66,490,037 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01747:Adamts17
|
APN |
7 |
66,701,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02081:Adamts17
|
APN |
7 |
66,711,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02152:Adamts17
|
APN |
7 |
66,774,748 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02264:Adamts17
|
APN |
7 |
66,697,207 (GRCm39) |
splice site |
probably null |
|
|
IGL02457:Adamts17
|
APN |
7 |
66,677,562 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02519:Adamts17
|
APN |
7 |
66,774,721 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02530:Adamts17
|
APN |
7 |
66,559,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02649:Adamts17
|
APN |
7 |
66,499,626 (GRCm39) |
splice site |
probably benign |
|
|
IGL02711:Adamts17
|
APN |
7 |
66,701,788 (GRCm39) |
splice site |
probably benign |
|
|
IGL03006:Adamts17
|
APN |
7 |
66,728,095 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL03203:Adamts17
|
APN |
7 |
66,711,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03343:Adamts17
|
APN |
7 |
66,725,064 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB007:Adamts17
|
UTSW |
7 |
66,499,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
BB017:Adamts17
|
UTSW |
7 |
66,499,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
E2594:Adamts17
|
UTSW |
7 |
66,654,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Adamts17
|
UTSW |
7 |
66,799,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0416:Adamts17
|
UTSW |
7 |
66,565,646 (GRCm39) |
splice site |
probably null |
|
|
R0635:Adamts17
|
UTSW |
7 |
66,558,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1083:Adamts17
|
UTSW |
7 |
66,797,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1476:Adamts17
|
UTSW |
7 |
66,725,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Adamts17
|
UTSW |
7 |
66,799,704 (GRCm39) |
nonsense |
probably null |
|
|
R1729:Adamts17
|
UTSW |
7 |
66,799,704 (GRCm39) |
nonsense |
probably null |
|
|
R1763:Adamts17
|
UTSW |
7 |
66,797,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1784:Adamts17
|
UTSW |
7 |
66,799,704 (GRCm39) |
nonsense |
probably null |
|
|
R1905:Adamts17
|
UTSW |
7 |
66,697,220 (GRCm39) |
nonsense |
probably null |
|
|
R1938:Adamts17
|
UTSW |
7 |
66,774,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Adamts17
|
UTSW |
7 |
66,774,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3796:Adamts17
|
UTSW |
7 |
66,489,662 (GRCm39) |
splice site |
probably null |
|
|
R3849:Adamts17
|
UTSW |
7 |
66,490,215 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3850:Adamts17
|
UTSW |
7 |
66,490,215 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3945:Adamts17
|
UTSW |
7 |
66,770,687 (GRCm39) |
missense |
probably benign |
|
|
R4519:Adamts17
|
UTSW |
7 |
66,490,314 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4554:Adamts17
|
UTSW |
7 |
66,677,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4555:Adamts17
|
UTSW |
7 |
66,677,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4556:Adamts17
|
UTSW |
7 |
66,677,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4557:Adamts17
|
UTSW |
7 |
66,677,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Adamts17
|
UTSW |
7 |
66,691,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Adamts17
|
UTSW |
7 |
66,654,218 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5019:Adamts17
|
UTSW |
7 |
66,711,818 (GRCm39) |
nonsense |
probably null |
|
|
R5438:Adamts17
|
UTSW |
7 |
66,538,165 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5444:Adamts17
|
UTSW |
7 |
66,691,647 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5673:Adamts17
|
UTSW |
7 |
66,691,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6326:Adamts17
|
UTSW |
7 |
66,770,636 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6964:Adamts17
|
UTSW |
7 |
66,654,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6964:Adamts17
|
UTSW |
7 |
66,559,148 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7129:Adamts17
|
UTSW |
7 |
66,770,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7317:Adamts17
|
UTSW |
7 |
66,490,304 (GRCm39) |
nonsense |
probably null |
|
|
R7355:Adamts17
|
UTSW |
7 |
66,725,052 (GRCm39) |
missense |
|
|
|
R7386:Adamts17
|
UTSW |
7 |
66,618,597 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7407:Adamts17
|
UTSW |
7 |
66,697,304 (GRCm39) |
nonsense |
probably null |
|
|
R7432:Adamts17
|
UTSW |
7 |
66,701,665 (GRCm39) |
missense |
|
|
|
R7782:Adamts17
|
UTSW |
7 |
66,774,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7817:Adamts17
|
UTSW |
7 |
66,559,224 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7930:Adamts17
|
UTSW |
7 |
66,499,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7993:Adamts17
|
UTSW |
7 |
66,499,612 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8178:Adamts17
|
UTSW |
7 |
66,499,464 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R9095:Adamts17
|
UTSW |
7 |
66,654,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Adamts17
|
UTSW |
7 |
66,489,648 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9303:Adamts17
|
UTSW |
7 |
66,489,645 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9305:Adamts17
|
UTSW |
7 |
66,489,645 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9505:Adamts17
|
UTSW |
7 |
66,774,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9668:Adamts17
|
UTSW |
7 |
66,797,438 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
X0022:Adamts17
|
UTSW |
7 |
66,691,649 (GRCm39) |
missense |
probably benign |
0.44 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGAAAGAGTGTGCTCACCCC -3'
(R):5'- ATTTCTTGAGCCCAGCTGC -3'
Sequencing Primer
(F):5'- GTGTGCTCACCCCAGACAAG -3'
(R):5'- AGCCCAGCTGCTCCCTC -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation