Incidental Mutation 'R8963:Ccdc88a'
| ID |
682504 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc88a
|
| Ensembl Gene |
ENSMUSG00000032740 |
| Gene Name |
coiled coil domain containing 88A |
| Synonyms |
GIV, Girdin, D130005J21Rik, HkRP1, C330012F17Rik, C130096N06Rik, A430106J12Rik |
| MMRRC Submission |
068797-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8963 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
29323658-29460808 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 29448416 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1465
(N1465K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048978
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040182]
[ENSMUST00000140194]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000040182
AA Change: N1465K
PolyPhen 2
Score 0.774 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000048978
Gene: ENSMUSG00000032740
AA Change: N1465K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HOOK
|
14 |
590 |
8.1e-36 |
PFAM |
|
low complexity region
|
614 |
625 |
N/A |
INTRINSIC |
|
Blast:BRLZ
|
665 |
719 |
6e-22 |
BLAST |
|
low complexity region
|
826 |
839 |
N/A |
INTRINSIC |
|
low complexity region
|
883 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1093 |
1104 |
N/A |
INTRINSIC |
|
coiled coil region
|
1268 |
1385 |
N/A |
INTRINSIC |
|
low complexity region
|
1437 |
1444 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1576 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1609 |
1702 |
2.38e-6 |
PROSPERO |
|
internal_repeat_1
|
1708 |
1808 |
2.38e-6 |
PROSPERO |
|
low complexity region
|
1811 |
1824 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000119173
Gene: ENSMUSG00000032740
AA Change: N445K
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
212 |
N/A |
INTRINSIC |
|
coiled coil region
|
248 |
365 |
N/A |
INTRINSIC |
|
low complexity region
|
418 |
425 |
N/A |
INTRINSIC |
|
low complexity region
|
547 |
557 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140194
AA Change: N193K
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000114942
Gene: ENSMUSG00000032740
AA Change: N193K
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
3 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
144 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
304 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal weight loss, reduced angiogenesis, and premature death by P25. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
T |
C |
11: 119,902,963 (GRCm39) |
T421A |
probably damaging |
Het |
| Adamts12 |
T |
C |
15: 11,317,443 (GRCm39) |
|
probably null |
Het |
| Adgrv1 |
A |
T |
13: 81,567,588 (GRCm39) |
V5195E |
probably benign |
Het |
| Adora2b |
C |
T |
11: 62,139,983 (GRCm39) |
A19V |
possibly damaging |
Het |
| Ankrd28 |
A |
G |
14: 31,477,698 (GRCm39) |
C115R |
probably benign |
Het |
| Ankrd35 |
T |
A |
3: 96,587,003 (GRCm39) |
L106* |
probably null |
Het |
| Ankrd44 |
G |
A |
1: 54,801,538 (GRCm39) |
A263V |
probably damaging |
Het |
| Apol7b |
T |
C |
15: 77,308,120 (GRCm39) |
K125R |
possibly damaging |
Het |
| Cacna1c |
A |
T |
6: 118,719,232 (GRCm39) |
L245* |
probably null |
Het |
| Cbll1 |
A |
T |
12: 31,538,199 (GRCm39) |
H185Q |
probably damaging |
Het |
| Ccdc150 |
A |
C |
1: 54,311,641 (GRCm39) |
N209T |
probably benign |
Het |
| Cfap54 |
C |
A |
10: 92,864,562 (GRCm39) |
G124* |
probably null |
Het |
| Chml |
A |
T |
1: 175,514,601 (GRCm39) |
L440H |
probably damaging |
Het |
| Chrnd |
A |
T |
1: 87,122,603 (GRCm39) |
Q128L |
probably damaging |
Het |
| Clvs2 |
A |
T |
10: 33,498,677 (GRCm39) |
D84E |
probably benign |
Het |
| Ctif |
CGGGGCACACTTTGCTCTTACCTCCCGGAGGCACGTGTAGATGGGGCACACTTTGCTCTTACCTCCCGGAGGCACGTGTAGATGGGGCACAC |
CGGGGCACACTTTGCTCTTACCTCCCGGAGGCACGTGTAGATGGGGCACAC |
18: 75,604,874 (GRCm39) |
|
probably benign |
Het |
| Cyp2c40 |
T |
A |
19: 39,755,926 (GRCm39) |
I463F |
possibly damaging |
Het |
| Cyp51 |
C |
A |
5: 4,136,519 (GRCm39) |
R425L |
probably damaging |
Het |
| Daam1 |
A |
G |
12: 71,992,018 (GRCm39) |
T279A |
unknown |
Het |
| Ebf2 |
G |
T |
14: 67,665,554 (GRCm39) |
V571F |
probably benign |
Het |
| Elapor2 |
T |
A |
5: 9,487,792 (GRCm39) |
N559K |
probably damaging |
Het |
| Elavl4 |
A |
T |
4: 110,063,776 (GRCm39) |
I275N |
probably damaging |
Het |
| F11r |
A |
G |
1: 171,288,505 (GRCm39) |
Q116R |
probably benign |
Het |
| Foxred2 |
T |
A |
15: 77,829,805 (GRCm39) |
D580V |
probably benign |
Het |
| Gatad1 |
A |
C |
5: 3,691,544 (GRCm39) |
L4R |
probably damaging |
Het |
| Gcn1 |
T |
A |
5: 115,727,153 (GRCm39) |
M670K |
probably benign |
Het |
| Greb1 |
A |
T |
12: 16,774,885 (GRCm39) |
F171I |
probably damaging |
Het |
| Grin2b |
A |
G |
6: 136,021,007 (GRCm39) |
V98A |
probably damaging |
Het |
| Helz2 |
A |
T |
2: 180,871,407 (GRCm39) |
V2735E |
probably damaging |
Het |
| Hrct1 |
A |
T |
4: 43,727,564 (GRCm39) |
|
probably benign |
Het |
| Ighv1-11 |
C |
T |
12: 114,575,864 (GRCm39) |
R117K |
probably damaging |
Het |
| Igkv12-46 |
A |
T |
6: 69,741,754 (GRCm39) |
S34T |
probably damaging |
Het |
| Il27ra |
T |
A |
8: 84,767,711 (GRCm39) |
N71Y |
probably damaging |
Het |
| Iqca1 |
G |
T |
1: 90,067,649 (GRCm39) |
H201N |
probably benign |
Het |
| Itgb1bp1 |
C |
T |
12: 21,324,864 (GRCm39) |
R64Q |
probably damaging |
Het |
| Katnb1 |
T |
C |
8: 95,809,519 (GRCm39) |
L13S |
probably damaging |
Het |
| Kif26b |
G |
A |
1: 178,743,714 (GRCm39) |
R1270Q |
probably benign |
Het |
| Klhdc2 |
A |
T |
12: 69,347,065 (GRCm39) |
R77* |
probably null |
Het |
| Klra10 |
A |
T |
6: 130,249,617 (GRCm39) |
|
probably null |
Het |
| Large1 |
A |
T |
8: 73,542,612 (GRCm39) |
I704N |
probably damaging |
Het |
| Lrp1b |
G |
A |
2: 40,888,196 (GRCm39) |
H2241Y |
probably benign |
Het |
| Lrpap1 |
T |
A |
5: 35,255,001 (GRCm39) |
M212L |
probably benign |
Het |
| Mab21l1 |
A |
G |
3: 55,690,348 (GRCm39) |
|
probably benign |
Het |
| Map4k4 |
A |
T |
1: 40,039,740 (GRCm39) |
Q44L |
probably damaging |
Het |
| Map7d1 |
A |
G |
4: 126,130,475 (GRCm39) |
S412P |
probably damaging |
Het |
| Me1 |
A |
T |
9: 86,480,844 (GRCm39) |
F354I |
probably damaging |
Het |
| Nlrp1b |
A |
G |
11: 71,108,658 (GRCm39) |
V281A |
probably damaging |
Het |
| Nrip2 |
A |
G |
6: 128,385,288 (GRCm39) |
T240A |
possibly damaging |
Het |
| Nsmaf |
A |
G |
4: 6,428,471 (GRCm39) |
V203A |
probably damaging |
Het |
| Or12e8 |
T |
A |
2: 87,187,950 (GRCm39) |
I54K |
possibly damaging |
Het |
| Or4g17 |
A |
T |
2: 111,209,645 (GRCm39) |
Q100L |
probably damaging |
Het |
| Or4n5 |
A |
T |
14: 50,132,509 (GRCm39) |
M250K |
probably benign |
Het |
| Or8g2 |
A |
G |
9: 39,821,495 (GRCm39) |
Y132C |
probably damaging |
Het |
| P4ha2 |
T |
C |
11: 54,004,995 (GRCm39) |
F124L |
probably benign |
Het |
| Pcdha9 |
A |
T |
18: 37,131,750 (GRCm39) |
D273V |
probably benign |
Het |
| Pkd1l3 |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
8: 110,350,827 (GRCm39) |
|
probably benign |
Het |
| Plxnd1 |
G |
T |
6: 115,949,506 (GRCm39) |
S760* |
probably null |
Het |
| Polr1b |
A |
G |
2: 128,957,576 (GRCm39) |
T544A |
probably benign |
Het |
| Polr2g |
T |
C |
19: 8,771,513 (GRCm39) |
D153G |
probably damaging |
Het |
| Pramel12 |
T |
C |
4: 143,144,229 (GRCm39) |
Y192H |
probably benign |
Het |
| Rad51ap2 |
A |
C |
12: 11,506,255 (GRCm39) |
E59A |
possibly damaging |
Het |
| Rrm1 |
A |
T |
7: 102,105,739 (GRCm39) |
Y285F |
probably benign |
Het |
| Ryr3 |
A |
G |
2: 112,667,015 (GRCm39) |
|
probably null |
Het |
| Scaf4 |
GGCTGCTGCTGCTGCTGCTGCTGCTG |
GGCTGCTGCTGCTGCTGCTGCTG |
16: 90,026,745 (GRCm39) |
|
probably benign |
Het |
| Sftpd |
A |
G |
14: 40,905,001 (GRCm39) |
V30A |
probably benign |
Het |
| Sirt6 |
A |
G |
10: 81,462,378 (GRCm39) |
V7A |
probably benign |
Het |
| Ska1 |
C |
T |
18: 74,330,639 (GRCm39) |
V188M |
probably damaging |
Het |
| Skint8 |
G |
A |
4: 111,794,241 (GRCm39) |
M210I |
probably benign |
Het |
| Slc6a11 |
A |
G |
6: 114,202,782 (GRCm39) |
|
probably null |
Het |
| Slc6a2 |
A |
T |
8: 93,715,702 (GRCm39) |
H280L |
probably benign |
Het |
| Sptan1 |
T |
C |
2: 29,873,744 (GRCm39) |
V208A |
possibly damaging |
Het |
| Taf6l |
T |
A |
19: 8,752,135 (GRCm39) |
T518S |
probably benign |
Het |
| Thoc2l |
T |
C |
5: 104,665,652 (GRCm39) |
V58A |
probably benign |
Het |
| Tsc22d1 |
T |
C |
14: 76,656,266 (GRCm39) |
M59T |
probably benign |
Het |
| Unc5cl |
A |
G |
17: 48,769,361 (GRCm39) |
T282A |
probably benign |
Het |
| Vav3 |
A |
G |
3: 109,590,229 (GRCm39) |
K260E |
probably damaging |
Het |
| Vmn2r53 |
A |
G |
7: 12,315,926 (GRCm39) |
V631A |
probably damaging |
Het |
| Zfp938 |
A |
T |
10: 82,061,287 (GRCm39) |
F444L |
possibly damaging |
Het |
|
| Other mutations in Ccdc88a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00499:Ccdc88a
|
APN |
11 |
29,449,341 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL00577:Ccdc88a
|
APN |
11 |
29,374,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00766:Ccdc88a
|
APN |
11 |
29,451,046 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01384:Ccdc88a
|
APN |
11 |
29,453,915 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01541:Ccdc88a
|
APN |
11 |
29,350,283 (GRCm39) |
missense |
probably benign |
|
|
IGL01647:Ccdc88a
|
APN |
11 |
29,454,321 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02648:Ccdc88a
|
APN |
11 |
29,451,051 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02885:Ccdc88a
|
APN |
11 |
29,398,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03117:Ccdc88a
|
APN |
11 |
29,324,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03196:Ccdc88a
|
APN |
11 |
29,432,340 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
trailor
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0108:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0326:Ccdc88a
|
UTSW |
11 |
29,411,021 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0565:Ccdc88a
|
UTSW |
11 |
29,411,042 (GRCm39) |
unclassified |
probably benign |
|
|
R0631:Ccdc88a
|
UTSW |
11 |
29,443,752 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Ccdc88a
|
UTSW |
11 |
29,432,749 (GRCm39) |
unclassified |
probably benign |
|
|
R0762:Ccdc88a
|
UTSW |
11 |
29,413,112 (GRCm39) |
unclassified |
probably benign |
|
|
R0838:Ccdc88a
|
UTSW |
11 |
29,350,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0946:Ccdc88a
|
UTSW |
11 |
29,406,509 (GRCm39) |
missense |
probably benign |
|
|
R1192:Ccdc88a
|
UTSW |
11 |
29,454,049 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R1500:Ccdc88a
|
UTSW |
11 |
29,432,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1701:Ccdc88a
|
UTSW |
11 |
29,427,427 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1826:Ccdc88a
|
UTSW |
11 |
29,439,637 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1902:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1903:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2021:Ccdc88a
|
UTSW |
11 |
29,453,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2023:Ccdc88a
|
UTSW |
11 |
29,413,546 (GRCm39) |
nonsense |
probably null |
|
|
R2284:Ccdc88a
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R3236:Ccdc88a
|
UTSW |
11 |
29,397,995 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R3409:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3410:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3411:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3430:Ccdc88a
|
UTSW |
11 |
29,398,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3620:Ccdc88a
|
UTSW |
11 |
29,380,227 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4204:Ccdc88a
|
UTSW |
11 |
29,413,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4515:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4518:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4519:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4693:Ccdc88a
|
UTSW |
11 |
29,432,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Ccdc88a
|
UTSW |
11 |
29,372,586 (GRCm39) |
missense |
probably benign |
|
|
R4707:Ccdc88a
|
UTSW |
11 |
29,397,956 (GRCm39) |
missense |
probably benign |
|
|
R4732:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4733:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4734:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4749:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4817:Ccdc88a
|
UTSW |
11 |
29,410,907 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4828:Ccdc88a
|
UTSW |
11 |
29,413,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ccdc88a
|
UTSW |
11 |
29,432,133 (GRCm39) |
nonsense |
probably null |
|
|
R5288:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5373:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5374:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5401:Ccdc88a
|
UTSW |
11 |
29,413,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5586:Ccdc88a
|
UTSW |
11 |
29,453,484 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ccdc88a
|
UTSW |
11 |
29,432,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7116:Ccdc88a
|
UTSW |
11 |
29,454,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7353:Ccdc88a
|
UTSW |
11 |
29,413,368 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7538:Ccdc88a
|
UTSW |
11 |
29,413,370 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7663:Ccdc88a
|
UTSW |
11 |
29,448,614 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7769:Ccdc88a
|
UTSW |
11 |
29,432,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Ccdc88a
|
UTSW |
11 |
29,427,348 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7810:Ccdc88a
|
UTSW |
11 |
29,435,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7826:Ccdc88a
|
UTSW |
11 |
29,453,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7956:Ccdc88a
|
UTSW |
11 |
29,413,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Ccdc88a
|
UTSW |
11 |
29,443,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8402:Ccdc88a
|
UTSW |
11 |
29,413,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8409:Ccdc88a
|
UTSW |
11 |
29,453,544 (GRCm39) |
missense |
probably benign |
|
|
R8555:Ccdc88a
|
UTSW |
11 |
29,380,169 (GRCm39) |
missense |
probably benign |
|
|
R8676:Ccdc88a
|
UTSW |
11 |
29,410,860 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8846:Ccdc88a
|
UTSW |
11 |
29,414,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8972:Ccdc88a
|
UTSW |
11 |
29,435,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9353:Ccdc88a
|
UTSW |
11 |
29,427,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Ccdc88a
|
UTSW |
11 |
29,453,922 (GRCm39) |
missense |
probably null |
0.55 |
|
R9385:Ccdc88a
|
UTSW |
11 |
29,405,422 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9509:Ccdc88a
|
UTSW |
11 |
29,414,143 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9610:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9611:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9664:Ccdc88a
|
UTSW |
11 |
29,405,484 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9720:Ccdc88a
|
UTSW |
11 |
29,413,813 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTTTTAAAGGCAGTTGGGGC -3'
(R):5'- AACTGCTTGGATCGGAAGGC -3'
Sequencing Primer
(F):5'- TTGAAAATCCATCAGCCTTTGG -3'
(R):5'- CTTGGATCGGAAGGCTGCAG -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation