Incidental Mutation 'R8968:Tanc2'
| ID |
682876 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc2
|
| Ensembl Gene |
ENSMUSG00000053580 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| Synonyms |
5730590C14Rik, 3526402J09Rik |
| MMRRC Submission |
068802-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8968 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
105480812-105820130 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 105758400 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 720
(D720E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100330]
|
| AlphaFold |
A2A690 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100330
AA Change: D720E
PolyPhen 2
Score 0.497 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000097904
Gene: ENSMUSG00000053580
AA Change: D720E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
129 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
823 |
834 |
N/A |
INTRINSIC |
|
ANK
|
846 |
878 |
2.08e3 |
SMART |
|
ANK
|
882 |
913 |
2.97e2 |
SMART |
|
ANK
|
917 |
946 |
5.75e-1 |
SMART |
|
ANK
|
950 |
979 |
8.62e1 |
SMART |
|
ANK
|
990 |
1018 |
1.16e3 |
SMART |
|
ANK
|
1033 |
1062 |
3.31e-1 |
SMART |
|
ANK
|
1066 |
1095 |
7.71e-2 |
SMART |
|
ANK
|
1099 |
1128 |
6.12e-5 |
SMART |
|
ANK
|
1132 |
1161 |
8.99e-3 |
SMART |
|
ANK
|
1165 |
1194 |
5.71e-5 |
SMART |
|
ANK
|
1198 |
1227 |
2.11e2 |
SMART |
|
TPR
|
1244 |
1277 |
3.89e1 |
SMART |
|
TPR
|
1291 |
1324 |
3.61e-2 |
SMART |
|
TPR
|
1325 |
1358 |
2.82e-4 |
SMART |
|
low complexity region
|
1369 |
1406 |
N/A |
INTRINSIC |
|
low complexity region
|
1533 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1787 |
1802 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 97.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector die prior to E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
T |
A |
13: 77,480,429 (GRCm39) |
L1153* |
probably null |
Het |
| Adamts2 |
T |
C |
11: 50,683,550 (GRCm39) |
I944T |
possibly damaging |
Het |
| Aqp9 |
A |
T |
9: 71,045,485 (GRCm39) |
C67* |
probably null |
Het |
| Armt1 |
G |
T |
10: 4,404,150 (GRCm39) |
G412W |
probably damaging |
Het |
| B4galt1 |
T |
C |
4: 40,807,243 (GRCm39) |
D381G |
probably benign |
Het |
| Bmp5 |
A |
T |
9: 75,780,579 (GRCm39) |
H292L |
probably benign |
Het |
| Brpf1 |
T |
C |
6: 113,299,510 (GRCm39) |
F1181S |
probably damaging |
Het |
| Btbd7 |
C |
A |
12: 102,779,025 (GRCm39) |
G414C |
probably damaging |
Het |
| Ccdc65 |
A |
T |
15: 98,616,723 (GRCm39) |
K204* |
probably null |
Het |
| Cdk5 |
T |
A |
5: 24,627,379 (GRCm39) |
K88M |
probably damaging |
Het |
| Cdrt4 |
T |
A |
11: 62,883,634 (GRCm39) |
L112Q |
probably damaging |
Het |
| Cenpb |
T |
C |
2: 131,020,547 (GRCm39) |
E417G |
unknown |
Het |
| Cep135 |
T |
C |
5: 76,754,576 (GRCm39) |
I351T |
possibly damaging |
Het |
| Ces1d |
A |
T |
8: 93,914,383 (GRCm39) |
S226R |
probably damaging |
Het |
| Cfap97 |
T |
A |
8: 46,623,114 (GRCm39) |
V168E |
possibly damaging |
Het |
| CN725425 |
T |
C |
15: 91,130,090 (GRCm39) |
C318R |
possibly damaging |
Het |
| Cnga3 |
T |
A |
1: 37,300,460 (GRCm39) |
D393E |
probably benign |
Het |
| Cplane1 |
A |
T |
15: 8,230,765 (GRCm39) |
H1014L |
possibly damaging |
Het |
| Cpsf1 |
G |
A |
15: 76,486,169 (GRCm39) |
R358* |
probably null |
Het |
| Cyp2b23 |
G |
A |
7: 26,378,963 (GRCm39) |
P167L |
probably damaging |
Het |
| Cyp2c70 |
A |
T |
19: 40,142,059 (GRCm39) |
H477Q |
probably benign |
Het |
| D930020B18Rik |
A |
C |
10: 121,490,721 (GRCm39) |
Y107S |
probably damaging |
Het |
| Dhrs1 |
A |
T |
14: 55,978,192 (GRCm39) |
F216I |
probably benign |
Het |
| Dmgdh |
A |
T |
13: 93,845,767 (GRCm39) |
K474* |
probably null |
Het |
| Dsp |
T |
C |
13: 38,335,596 (GRCm39) |
I11T |
possibly damaging |
Het |
| Erh |
G |
T |
12: 80,684,282 (GRCm39) |
A65E |
probably benign |
Het |
| Fmnl1 |
AGGCTCTGG |
AGG |
11: 103,077,444 (GRCm39) |
|
probably benign |
Het |
| Grid2 |
A |
C |
6: 64,643,139 (GRCm39) |
H967P |
probably benign |
Het |
| Hc |
A |
G |
2: 34,922,317 (GRCm39) |
I503T |
possibly damaging |
Het |
| Herc3 |
T |
C |
6: 58,867,183 (GRCm39) |
L824S |
probably damaging |
Het |
| Hfm1 |
T |
C |
5: 107,065,439 (GRCm39) |
D80G |
probably benign |
Het |
| Hjurp |
CTCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCT |
C |
1: 88,193,999 (GRCm39) |
|
probably benign |
Het |
| Hspa1l |
A |
G |
17: 35,196,230 (GRCm39) |
K90E |
possibly damaging |
Het |
| Impa2 |
G |
A |
18: 67,451,497 (GRCm39) |
V264I |
probably benign |
Het |
| Ipmk |
C |
T |
10: 71,199,333 (GRCm39) |
R65W |
probably damaging |
Het |
| Klhl38 |
C |
T |
15: 58,185,500 (GRCm39) |
V410I |
probably benign |
Het |
| Lcn4 |
A |
G |
2: 26,558,360 (GRCm39) |
I175T |
possibly damaging |
Het |
| Lipo2 |
C |
A |
19: 33,726,917 (GRCm39) |
W40L |
probably damaging |
Het |
| Mgam |
A |
T |
6: 40,734,745 (GRCm39) |
|
probably null |
Het |
| Myo16 |
T |
A |
8: 10,619,700 (GRCm39) |
I1417N |
unknown |
Het |
| Or2n1d |
A |
T |
17: 38,646,320 (GRCm39) |
T91S |
possibly damaging |
Het |
| Or4a66 |
T |
A |
2: 88,531,137 (GRCm39) |
I179F |
probably benign |
Het |
| Or52e19b |
A |
T |
7: 103,032,667 (GRCm39) |
C181S |
probably damaging |
Het |
| Or5j3 |
G |
A |
2: 86,128,526 (GRCm39) |
R122H |
probably benign |
Het |
| Pcdha11 |
A |
G |
18: 37,145,307 (GRCm39) |
N466S |
probably damaging |
Het |
| Pif1 |
C |
T |
9: 65,499,076 (GRCm39) |
T432M |
probably damaging |
Het |
| Pigt |
CCAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGAT |
CCAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGAT |
2: 164,341,589 (GRCm39) |
|
probably null |
Het |
| Pkd1l3 |
CCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACACAGGTGACATCAGACACACCTGCATCCAATAGCCCACCACAGGGGACATCAGACACACCTGGATTCAGCAGCCCAACACAGGTGACAACAGCCACACTTGTATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACATCTGCATCCATCAGCCCACCACAGGTAATATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACA |
CCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACACAGGTGACATCAGACACACCTGCATCCAATAGCCCACCACAGGGGACATCAGACACACCTGGATTCAGCAGCCCAACACAGGTGACAACAGCCACACTTGTATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACATCTGCATCCATCAGCCCACCACAGGTAATATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACA |
8: 110,350,420 (GRCm39) |
|
probably benign |
Het |
| Pole |
T |
C |
5: 110,459,949 (GRCm39) |
S1118P |
possibly damaging |
Het |
| Ppp4r4 |
T |
C |
12: 103,566,706 (GRCm39) |
M652T |
probably benign |
Het |
| Prex2 |
A |
T |
1: 11,180,562 (GRCm39) |
K376* |
probably null |
Het |
| Prps1l1 |
A |
T |
12: 35,035,205 (GRCm39) |
I107F |
probably damaging |
Het |
| Resf1 |
T |
A |
6: 149,228,664 (GRCm39) |
V570D |
probably damaging |
Het |
| Rfc1 |
C |
T |
5: 65,432,778 (GRCm39) |
V761I |
probably benign |
Het |
| Ripk4 |
T |
C |
16: 97,547,203 (GRCm39) |
E353G |
probably benign |
Het |
| Robo2 |
C |
A |
16: 73,767,941 (GRCm39) |
|
probably null |
Het |
| Rrm1 |
C |
T |
7: 102,117,545 (GRCm39) |
A745V |
probably benign |
Het |
| Sash1 |
A |
T |
10: 8,606,179 (GRCm39) |
V737D |
probably benign |
Het |
| Sel1l2 |
T |
C |
2: 140,127,209 (GRCm39) |
K101E |
probably benign |
Het |
| Selenbp2 |
A |
T |
3: 94,607,337 (GRCm39) |
I253F |
probably benign |
Het |
| Setd1a |
C |
T |
7: 127,385,279 (GRCm39) |
P662L |
possibly damaging |
Het |
| Slc16a6 |
C |
T |
11: 109,345,776 (GRCm39) |
V496I |
possibly damaging |
Het |
| Slc4a4 |
A |
T |
5: 89,232,512 (GRCm39) |
M239L |
probably benign |
Het |
| Slc7a8 |
G |
C |
14: 55,018,750 (GRCm39) |
A12G |
probably benign |
Het |
| Snx30 |
T |
C |
4: 59,886,517 (GRCm39) |
S309P |
possibly damaging |
Het |
| Spen |
T |
C |
4: 141,197,701 (GRCm39) |
N3389S |
probably benign |
Het |
| Spg11 |
T |
C |
2: 121,922,687 (GRCm39) |
T921A |
probably damaging |
Het |
| Tmprss9 |
A |
T |
10: 80,730,163 (GRCm39) |
I688F |
possibly damaging |
Het |
| Trap1 |
A |
G |
16: 3,862,490 (GRCm39) |
V596A |
possibly damaging |
Het |
| Ttc32 |
G |
T |
12: 9,080,187 (GRCm39) |
R44L |
probably benign |
Het |
| Tusc3 |
T |
A |
8: 39,597,898 (GRCm39) |
N288K |
probably benign |
Het |
| Ush2a |
G |
A |
1: 188,127,956 (GRCm39) |
G656E |
probably damaging |
Het |
| Vill |
T |
C |
9: 118,892,671 (GRCm39) |
|
probably null |
Het |
| Vmn1r5 |
A |
T |
6: 56,963,182 (GRCm39) |
R286* |
probably null |
Het |
| Vmn2r14 |
T |
C |
5: 109,365,533 (GRCm39) |
T514A |
probably benign |
Het |
| Vmn2r32 |
G |
A |
7: 7,477,204 (GRCm39) |
H396Y |
probably benign |
Het |
| Vmn2r75 |
A |
T |
7: 85,820,765 (GRCm39) |
Y56* |
probably null |
Het |
| Wdfy3 |
C |
T |
5: 102,011,983 (GRCm39) |
S2668N |
probably benign |
Het |
| Wdr72 |
G |
A |
9: 74,059,729 (GRCm39) |
D392N |
probably benign |
Het |
| Zfp518a |
A |
C |
19: 40,901,870 (GRCm39) |
K600Q |
possibly damaging |
Het |
|
| Other mutations in Tanc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Tanc2
|
APN |
11 |
105,814,046 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00688:Tanc2
|
APN |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00709:Tanc2
|
APN |
11 |
105,689,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01013:Tanc2
|
APN |
11 |
105,515,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01141:Tanc2
|
APN |
11 |
105,777,300 (GRCm39) |
splice site |
probably benign |
|
|
IGL01386:Tanc2
|
APN |
11 |
105,777,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01433:Tanc2
|
APN |
11 |
105,701,348 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01562:Tanc2
|
APN |
11 |
105,670,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01979:Tanc2
|
APN |
11 |
105,667,746 (GRCm39) |
missense |
probably benign |
|
|
IGL02104:Tanc2
|
APN |
11 |
105,670,959 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02434:Tanc2
|
APN |
11 |
105,670,868 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02534:Tanc2
|
APN |
11 |
105,725,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Tanc2
|
APN |
11 |
105,667,777 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Tanc2
|
APN |
11 |
105,803,918 (GRCm39) |
splice site |
probably null |
|
|
R0595:Tanc2
|
UTSW |
11 |
105,605,003 (GRCm39) |
splice site |
probably null |
|
|
R1131:Tanc2
|
UTSW |
11 |
105,725,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1320:Tanc2
|
UTSW |
11 |
105,777,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tanc2
|
UTSW |
11 |
105,814,460 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1497:Tanc2
|
UTSW |
11 |
105,812,963 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1692:Tanc2
|
UTSW |
11 |
105,748,326 (GRCm39) |
missense |
probably benign |
|
|
R1712:Tanc2
|
UTSW |
11 |
105,790,606 (GRCm39) |
missense |
probably benign |
|
|
R1793:Tanc2
|
UTSW |
11 |
105,515,859 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1812:Tanc2
|
UTSW |
11 |
105,777,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1905:Tanc2
|
UTSW |
11 |
105,813,689 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1959:Tanc2
|
UTSW |
11 |
105,801,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Tanc2
|
UTSW |
11 |
105,689,558 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2122:Tanc2
|
UTSW |
11 |
105,786,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Tanc2
|
UTSW |
11 |
105,801,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2341:Tanc2
|
UTSW |
11 |
105,725,877 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2497:Tanc2
|
UTSW |
11 |
105,564,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3438:Tanc2
|
UTSW |
11 |
105,748,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3711:Tanc2
|
UTSW |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3765:Tanc2
|
UTSW |
11 |
105,805,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Tanc2
|
UTSW |
11 |
105,689,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Tanc2
|
UTSW |
11 |
105,804,888 (GRCm39) |
intron |
probably benign |
|
|
R4609:Tanc2
|
UTSW |
11 |
105,801,066 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4674:Tanc2
|
UTSW |
11 |
105,758,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Tanc2
|
UTSW |
11 |
105,758,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Tanc2
|
UTSW |
11 |
105,515,886 (GRCm39) |
start codon destroyed |
probably null |
0.46 |
|
R5010:Tanc2
|
UTSW |
11 |
105,670,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Tanc2
|
UTSW |
11 |
105,748,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5385:Tanc2
|
UTSW |
11 |
105,667,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5409:Tanc2
|
UTSW |
11 |
105,758,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5419:Tanc2
|
UTSW |
11 |
105,813,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5501:Tanc2
|
UTSW |
11 |
105,805,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Tanc2
|
UTSW |
11 |
105,814,132 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5651:Tanc2
|
UTSW |
11 |
105,689,526 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5798:Tanc2
|
UTSW |
11 |
105,812,681 (GRCm39) |
small deletion |
probably benign |
|
|
R5876:Tanc2
|
UTSW |
11 |
105,813,439 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5889:Tanc2
|
UTSW |
11 |
105,812,633 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5958:Tanc2
|
UTSW |
11 |
105,731,451 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5999:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,814,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6025:Tanc2
|
UTSW |
11 |
105,787,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6025:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6185:Tanc2
|
UTSW |
11 |
105,803,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Tanc2
|
UTSW |
11 |
105,748,382 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6821:Tanc2
|
UTSW |
11 |
105,777,316 (GRCm39) |
splice site |
probably null |
|
|
R6846:Tanc2
|
UTSW |
11 |
105,689,479 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6857:Tanc2
|
UTSW |
11 |
105,801,114 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6904:Tanc2
|
UTSW |
11 |
105,726,056 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7009:Tanc2
|
UTSW |
11 |
105,731,525 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7017:Tanc2
|
UTSW |
11 |
105,813,934 (GRCm39) |
missense |
probably benign |
|
|
R7371:Tanc2
|
UTSW |
11 |
105,689,422 (GRCm39) |
missense |
probably benign |
|
|
R7556:Tanc2
|
UTSW |
11 |
105,799,857 (GRCm39) |
missense |
|
|
|
R7630:Tanc2
|
UTSW |
11 |
105,667,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7693:Tanc2
|
UTSW |
11 |
105,814,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Tanc2
|
UTSW |
11 |
105,667,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7807:Tanc2
|
UTSW |
11 |
105,758,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7878:Tanc2
|
UTSW |
11 |
105,804,241 (GRCm39) |
missense |
|
|
|
R7895:Tanc2
|
UTSW |
11 |
105,812,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Tanc2
|
UTSW |
11 |
105,787,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Tanc2
|
UTSW |
11 |
105,754,833 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Tanc2
|
UTSW |
11 |
105,725,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8133:Tanc2
|
UTSW |
11 |
105,814,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8422:Tanc2
|
UTSW |
11 |
105,726,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8527:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8542:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8834:Tanc2
|
UTSW |
11 |
105,807,845 (GRCm39) |
missense |
|
|
|
R8912:Tanc2
|
UTSW |
11 |
105,758,153 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8927:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8928:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9065:Tanc2
|
UTSW |
11 |
105,689,518 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Tanc2
|
UTSW |
11 |
105,758,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9108:Tanc2
|
UTSW |
11 |
105,810,580 (GRCm39) |
intron |
probably benign |
|
|
R9131:Tanc2
|
UTSW |
11 |
105,689,603 (GRCm39) |
missense |
probably benign |
|
|
R9294:Tanc2
|
UTSW |
11 |
105,777,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9445:Tanc2
|
UTSW |
11 |
105,758,290 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0027:Tanc2
|
UTSW |
11 |
105,726,009 (GRCm39) |
missense |
probably benign |
0.26 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATAGAGAAAGGCTACCTAGTGC -3'
(R):5'- AGGCTCAGACTCACTTATCACAG -3'
Sequencing Primer
(F):5'- GGCTACCTAGTGCTAAAGAGTTC -3'
(R):5'- CTATATCTTACCTGGGATCACAGAG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation