Mutagenetix > Incidental Mutation

Incidental Mutation 'R8968:2410089E03Rik'

682888

Institutional Source

Beutler Lab

Gene Symbol

2410089E03Rik

Ensembl Gene

ENSMUSG00000039801

Gene Name

RIKEN cDNA 2410089E03 gene

Synonyms

b2b012Clo

MMRRC Submission

068802-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R8968 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

8169106-8271158 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 8201281 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Leucine at position 1014 (H1014L)

Ref Sequence

ENSEMBL: ENSMUSP00000106247 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000110617]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000110617
AA Change: H1014L

PolyPhen 2 Score 0.842 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000106247
Gene: ENSMUSG00000039801
AA Change: H1014L

Domain	Start	End	E-Value	Type
low complexity region	144	157	N/A	INTRINSIC
low complexity region	338	352	N/A	INTRINSIC
low complexity region	466	476	N/A	INTRINSIC
low complexity region	868	883	N/A	INTRINSIC
low complexity region	949	962	N/A	INTRINSIC
low complexity region	1400	1415	N/A	INTRINSIC
low complexity region	1449	1464	N/A	INTRINSIC
low complexity region	1827	1838	N/A	INTRINSIC
low complexity region	1919	1930	N/A	INTRINSIC
low complexity region	2130	2145	N/A	INTRINSIC
coiled coil region	2750	2782	N/A	INTRINSIC
low complexity region	2838	2850	N/A	INTRINSIC
Pfam:Joubert	2894	3207	1.9e-136	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.4%
20x: 97.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. Defects in this gene are a cause of Joubert syndrome (JBTS). [provided by RefSeq, May 2012]
PHENOTYPE: Homozygotes exhibit double outlet right ventricle {SDD}, pulmonary atresia/hypolastic pulmonary artery, atrioventricular septal defect, and right aortic arch. Non-cardiovascular defects include cleft palate, polydactyly, transparent chest wall (sternal bone hypoplasia) and hypoplastic lungs. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 80 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2210408I21Rik	T	A	13: 77,332,310 (GRCm38)	L1153*	probably null	Het
2810474O19Rik	T	A	6: 149,327,166 (GRCm38)	V570D	probably damaging	Het
Adamts2	T	C	11: 50,792,723 (GRCm38)	I944T	possibly damaging	Het
Aqp9	A	T	9: 71,138,203 (GRCm38)	C67*	probably null	Het
Armt1	G	T	10: 4,454,150 (GRCm38)	G412W	probably damaging	Het
B4galt1	T	C	4: 40,807,243 (GRCm38)	D381G	probably benign	Het
Bmp5	A	T	9: 75,873,297 (GRCm38)	H292L	probably benign	Het
Brpf1	T	C	6: 113,322,549 (GRCm38)	F1181S	probably damaging	Het
Btbd7	C	A	12: 102,812,766 (GRCm38)	G414C	probably damaging	Het
Ccdc65	A	T	15: 98,718,842 (GRCm38)	K204*	probably null	Het
Cdk5	T	A	5: 24,422,381 (GRCm38)	K88M	probably damaging	Het
Cdrt4	T	A	11: 62,992,808 (GRCm38)	L112Q	probably damaging	Het
Cenpb	T	C	2: 131,178,627 (GRCm38)	E417G	unknown	Het
Cep135	T	C	5: 76,606,729 (GRCm38)	I351T	possibly damaging	Het
Ces1d	A	T	8: 93,187,755 (GRCm38)	S226R	probably damaging	Het
Cfap97	T	A	8: 46,170,077 (GRCm38)	V168E	possibly damaging	Het
CN725425	T	C	15: 91,245,887 (GRCm38)	C318R	possibly damaging	Het
Cnga3	T	A	1: 37,261,379 (GRCm38)	D393E	probably benign	Het
Cpsf1	G	A	15: 76,601,969 (GRCm38)	R358*	probably null	Het
Cyp2b23	G	A	7: 26,679,538 (GRCm38)	P167L	probably damaging	Het
Cyp2c70	A	T	19: 40,153,615 (GRCm38)	H477Q	probably benign	Het
D930020B18Rik	A	C	10: 121,654,816 (GRCm38)	Y107S	probably damaging	Het
Dhrs1	A	T	14: 55,740,735 (GRCm38)	F216I	probably benign	Het
Dmgdh	A	T	13: 93,709,259 (GRCm38)	K474*	probably null	Het
Dsp	T	C	13: 38,151,620 (GRCm38)	I11T	possibly damaging	Het
Erh	G	T	12: 80,637,508 (GRCm38)	A65E	probably benign	Het
Fmnl1	AGGCTCTGG	AGG	11: 103,186,618 (GRCm38)		probably benign	Het
Grid2	A	C	6: 64,666,155 (GRCm38)	H967P	probably benign	Het
Hc	A	G	2: 35,032,305 (GRCm38)	I503T	possibly damaging	Het
Herc3	T	C	6: 58,890,198 (GRCm38)	L824S	probably damaging	Het
Hfm1	T	C	5: 106,917,573 (GRCm38)	D80G	probably benign	Het
Hjurp	CTCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCT	C	1: 88,266,277 (GRCm38)		probably benign	Het
Hspa1l	A	G	17: 34,977,254 (GRCm38)	K90E	possibly damaging	Het
Impa2	G	A	18: 67,318,427 (GRCm38)	V264I	probably benign	Het
Ipmk	C	T	10: 71,363,503 (GRCm38)	R65W	probably damaging	Het
Klhl38	C	T	15: 58,322,104 (GRCm38)	V410I	probably benign	Het
Lcn4	A	G	2: 26,668,348 (GRCm38)	I175T	possibly damaging	Het
Lipo2	C	A	19: 33,749,517 (GRCm38)	W40L	probably damaging	Het
Mgam	A	T	6: 40,757,811 (GRCm38)		probably null	Het
Myo16	T	A	8: 10,569,700 (GRCm38)	I1417N	unknown	Het
Olfr1052	G	A	2: 86,298,182 (GRCm38)	R122H	probably benign	Het
Olfr1196	T	A	2: 88,700,793 (GRCm38)	I179F	probably benign	Het
Olfr136	A	T	17: 38,335,429 (GRCm38)	T91S	possibly damaging	Het
Olfr603	A	T	7: 103,383,460 (GRCm38)	C181S	probably damaging	Het
Pcdha11	A	G	18: 37,012,254 (GRCm38)	N466S	probably damaging	Het
Pif1	C	T	9: 65,591,794 (GRCm38)	T432M	probably damaging	Het
Pigt	CCAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGAT	CCAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGAT	2: 164,499,669 (GRCm38)		probably null	Het
Pkd1l3	CCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACACAGGTGACATCAGACACACCTGCATCCAATAGCCCACCACAGGGGACATCAGACACACCTGGATTCAGCAGCCCAACACAGGTGACAACAGCCACACTTGTATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACATCTGCATCCATCAGCCCACCACAGGTAATATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACA	CCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACACAGGTGACATCAGACACACCTGCATCCAATAGCCCACCACAGGGGACATCAGACACACCTGGATTCAGCAGCCCAACACAGGTGACAACAGCCACACTTGTATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGACACATCTGCATCCATCAGCCCACCACAGGTAATATCAGACACACCTGCATCCAGCAGCCCACCACAGGTGACATCAGAGACACCTGCATCCAGCAGCCCAACA	8: 109,623,788 (GRCm38)		probably benign	Het
Pole	T	C	5: 110,312,083 (GRCm38)	S1118P	possibly damaging	Het
Ppp4r4	T	C	12: 103,600,447 (GRCm38)	M652T	probably benign	Het
Prex2	A	T	1: 11,110,338 (GRCm38)	K376*	probably null	Het
Prps1l1	A	T	12: 34,985,206 (GRCm38)	I107F	probably damaging	Het
Rfc1	C	T	5: 65,275,435 (GRCm38)	V761I	probably benign	Het
Ripk4	T	C	16: 97,746,003 (GRCm38)	E353G	probably benign	Het
Robo2	C	A	16: 73,971,053 (GRCm38)		probably null	Het
Rrm1	C	T	7: 102,468,338 (GRCm38)	A745V	probably benign	Het
Sash1	A	T	10: 8,730,415 (GRCm38)	V737D	probably benign	Het
Sel1l2	T	C	2: 140,285,289 (GRCm38)	K101E	probably benign	Het
Selenbp2	A	T	3: 94,700,030 (GRCm38)	I253F	probably benign	Het
Setd1a	C	T	7: 127,786,107 (GRCm38)	P662L	possibly damaging	Het
Slc16a6	C	T	11: 109,454,950 (GRCm38)	V496I	possibly damaging	Het
Slc4a4	A	T	5: 89,084,653 (GRCm38)	M239L	probably benign	Het
Slc7a8	G	C	14: 54,781,293 (GRCm38)	A12G	probably benign	Het
Snx30	T	C	4: 59,886,517 (GRCm38)	S309P	possibly damaging	Het
Spen	T	C	4: 141,470,390 (GRCm38)	N3389S	probably benign	Het
Spg11	T	C	2: 122,092,206 (GRCm38)	T921A	probably damaging	Het
Tanc2	T	A	11: 105,867,574 (GRCm38)	D720E	possibly damaging	Het
Tmprss9	A	T	10: 80,894,329 (GRCm38)	I688F	possibly damaging	Het
Trap1	A	G	16: 4,044,626 (GRCm38)	V596A	possibly damaging	Het
Ttc32	G	T	12: 9,030,187 (GRCm38)	R44L	probably benign	Het
Tusc3	T	A	8: 39,130,744 (GRCm38)	N288K	probably benign	Het
Ush2a	G	A	1: 188,395,759 (GRCm38)	G656E	probably damaging	Het
Vill	T	C	9: 119,063,603 (GRCm38)		probably null	Het
Vmn1r5	A	T	6: 56,986,197 (GRCm38)	R286*	probably null	Het
Vmn2r14	T	C	5: 109,217,667 (GRCm38)	T514A	probably benign	Het
Vmn2r32	G	A	7: 7,474,205 (GRCm38)	H396Y	probably benign	Het
Vmn2r75	A	T	7: 86,171,557 (GRCm38)	Y56*	probably null	Het
Wdfy3	C	T	5: 101,864,117 (GRCm38)	S2668N	probably benign	Het
Wdr72	G	A	9: 74,152,447 (GRCm38)	D392N	probably benign	Het
Zfp518a	A	C	19: 40,913,426 (GRCm38)	K600Q	possibly damaging	Het

Other mutations in 2410089E03Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00756:2410089E03Rik	APN	15	8,264,447 (GRCm38)	splice site	probably benign
IGL00766:2410089E03Rik	APN	15	8,252,164 (GRCm38)	missense	unknown
IGL01483:2410089E03Rik	APN	15	8,187,107 (GRCm38)	missense	probably damaging	0.98
IGL01520:2410089E03Rik	APN	15	8,221,911 (GRCm38)	missense	probably damaging	0.96
IGL01578:2410089E03Rik	APN	15	8,270,710 (GRCm38)	missense	unknown
IGL01701:2410089E03Rik	APN	15	8,203,257 (GRCm38)	splice site	probably benign
IGL01892:2410089E03Rik	APN	15	8,242,265 (GRCm38)	splice site	probably benign
IGL01895:2410089E03Rik	APN	15	8,229,107 (GRCm38)	missense	possibly damaging	0.63
IGL01922:2410089E03Rik	APN	15	8,270,821 (GRCm38)	missense	unknown
IGL01978:2410089E03Rik	APN	15	8,219,382 (GRCm38)	missense	probably damaging	0.98
IGL02031:2410089E03Rik	APN	15	8,179,769 (GRCm38)	missense	probably damaging	0.99
IGL02318:2410089E03Rik	APN	15	8,175,025 (GRCm38)	missense	probably damaging	0.98
IGL02321:2410089E03Rik	APN	15	8,216,572 (GRCm38)	missense	probably benign	0.04
IGL02363:2410089E03Rik	APN	15	8,218,437 (GRCm38)	missense	possibly damaging	0.68
IGL02404:2410089E03Rik	APN	15	8,187,284 (GRCm38)	missense	possibly damaging	0.48
IGL02535:2410089E03Rik	APN	15	8,174,838 (GRCm38)	missense	probably damaging	1.00
IGL02732:2410089E03Rik	APN	15	8,179,891 (GRCm38)	missense	probably benign	0.03
IGL02895:2410089E03Rik	APN	15	8,232,107 (GRCm38)	splice site	probably benign
IGL02903:2410089E03Rik	APN	15	8,269,778 (GRCm38)	missense	unknown
IGL02903:2410089E03Rik	APN	15	8,269,779 (GRCm38)	missense	unknown
IGL02979:2410089E03Rik	APN	15	8,218,554 (GRCm38)	missense	possibly damaging	0.82
IGL03077:2410089E03Rik	APN	15	8,212,795 (GRCm38)	splice site	probably benign
IGL03196:2410089E03Rik	APN	15	8,201,342 (GRCm38)	missense	probably damaging	0.98
IGL03344:2410089E03Rik	APN	15	8,187,458 (GRCm38)	missense	possibly damaging	0.63
IGL03368:2410089E03Rik	APN	15	8,222,373 (GRCm38)	missense	probably benign	0.06
IGL03403:2410089E03Rik	APN	15	8,201,342 (GRCm38)	missense	probably damaging	0.98
agnes	UTSW	15	8,246,938 (GRCm38)	nonsense	probably null
dei	UTSW	15	8,186,165 (GRCm38)	missense	probably damaging	1.00
R0015:2410089E03Rik	UTSW	15	8,186,184 (GRCm38)	missense	probably damaging	1.00
R0015:2410089E03Rik	UTSW	15	8,186,184 (GRCm38)	missense	probably damaging	1.00
R0101:2410089E03Rik	UTSW	15	8,220,960 (GRCm38)	missense	probably benign	0.00
R0105:2410089E03Rik	UTSW	15	8,187,392 (GRCm38)	missense	probably benign
R0105:2410089E03Rik	UTSW	15	8,187,392 (GRCm38)	missense	probably benign
R0165:2410089E03Rik	UTSW	15	8,216,382 (GRCm38)	missense	probably damaging	1.00
R0306:2410089E03Rik	UTSW	15	8,179,889 (GRCm38)	missense	probably damaging	1.00
R0433:2410089E03Rik	UTSW	15	8,216,562 (GRCm38)	missense	probably benign	0.00
R0491:2410089E03Rik	UTSW	15	8,182,243 (GRCm38)	missense	probably damaging	1.00
R0523:2410089E03Rik	UTSW	15	8,194,386 (GRCm38)	missense	probably damaging	1.00
R0571:2410089E03Rik	UTSW	15	8,259,793 (GRCm38)	missense	unknown
R0679:2410089E03Rik	UTSW	15	8,223,122 (GRCm38)	missense	probably benign	0.39
R0704:2410089E03Rik	UTSW	15	8,210,083 (GRCm38)	missense	possibly damaging	0.93
R0707:2410089E03Rik	UTSW	15	8,258,321 (GRCm38)	missense	unknown
R0715:2410089E03Rik	UTSW	15	8,223,092 (GRCm38)	missense	probably benign	0.14
R0762:2410089E03Rik	UTSW	15	8,218,416 (GRCm38)	unclassified	probably benign
R0830:2410089E03Rik	UTSW	15	8,247,185 (GRCm38)	missense	unknown
R0924:2410089E03Rik	UTSW	15	8,251,070 (GRCm38)	splice site	probably benign
R1071:2410089E03Rik	UTSW	15	8,218,426 (GRCm38)	missense	probably benign	0.20
R1184:2410089E03Rik	UTSW	15	8,216,487 (GRCm38)	missense	probably benign
R1224:2410089E03Rik	UTSW	15	8,178,385 (GRCm38)	missense	probably benign	0.06
R1416:2410089E03Rik	UTSW	15	8,246,938 (GRCm38)	nonsense	probably null
R1428:2410089E03Rik	UTSW	15	8,219,369 (GRCm38)	missense	possibly damaging	0.83
R1487:2410089E03Rik	UTSW	15	8,186,231 (GRCm38)	missense	probably damaging	1.00
R1641:2410089E03Rik	UTSW	15	8,228,959 (GRCm38)	missense	probably benign	0.41
R1652:2410089E03Rik	UTSW	15	8,201,146 (GRCm38)	missense	probably damaging	1.00
R1688:2410089E03Rik	UTSW	15	8,228,609 (GRCm38)	missense	probably benign	0.00
R1715:2410089E03Rik	UTSW	15	8,226,900 (GRCm38)	splice site	probably null
R1820:2410089E03Rik	UTSW	15	8,269,645 (GRCm38)	missense	unknown
R1863:2410089E03Rik	UTSW	15	8,228,593 (GRCm38)	missense	probably benign	0.00
R1940:2410089E03Rik	UTSW	15	8,233,852 (GRCm38)	missense	probably damaging	0.98
R1967:2410089E03Rik	UTSW	15	8,203,420 (GRCm38)	missense	probably benign	0.09
R2064:2410089E03Rik	UTSW	15	8,186,165 (GRCm38)	missense	probably damaging	1.00
R2076:2410089E03Rik	UTSW	15	8,219,257 (GRCm38)	missense	possibly damaging	0.93
R2163:2410089E03Rik	UTSW	15	8,203,251 (GRCm38)	splice site	probably null
R2208:2410089E03Rik	UTSW	15	8,194,403 (GRCm38)	missense	probably benign	0.33
R2504:2410089E03Rik	UTSW	15	8,219,216 (GRCm38)	missense	probably damaging	0.99
R2568:2410089E03Rik	UTSW	15	8,201,269 (GRCm38)	missense	possibly damaging	0.70
R2845:2410089E03Rik	UTSW	15	8,216,380 (GRCm38)	missense	probably damaging	1.00
R2913:2410089E03Rik	UTSW	15	8,270,685 (GRCm38)	missense	unknown
R3056:2410089E03Rik	UTSW	15	8,251,007 (GRCm38)	missense	unknown
R3706:2410089E03Rik	UTSW	15	8,259,816 (GRCm38)	missense	unknown
R3707:2410089E03Rik	UTSW	15	8,259,816 (GRCm38)	missense	unknown
R3870:2410089E03Rik	UTSW	15	8,218,464 (GRCm38)	missense	probably damaging	0.98
R3877:2410089E03Rik	UTSW	15	8,221,943 (GRCm38)	missense	probably benign
R3886:2410089E03Rik	UTSW	15	8,171,805 (GRCm38)	missense	probably damaging	0.98
R4057:2410089E03Rik	UTSW	15	8,219,025 (GRCm38)	missense	probably benign	0.08
R4090:2410089E03Rik	UTSW	15	8,212,358 (GRCm38)	splice site	probably null
R4362:2410089E03Rik	UTSW	15	8,270,745 (GRCm38)	missense	unknown
R4363:2410089E03Rik	UTSW	15	8,270,745 (GRCm38)	missense	unknown
R4445:2410089E03Rik	UTSW	15	8,252,188 (GRCm38)	missense	unknown
R4581:2410089E03Rik	UTSW	15	8,171,798 (GRCm38)	missense	possibly damaging	0.85
R4587:2410089E03Rik	UTSW	15	8,201,152 (GRCm38)	missense	possibly damaging	0.50
R4659:2410089E03Rik	UTSW	15	8,216,276 (GRCm38)	intron	probably benign
R4663:2410089E03Rik	UTSW	15	8,218,455 (GRCm38)	missense	probably benign	0.31
R4779:2410089E03Rik	UTSW	15	8,218,838 (GRCm38)	missense	probably benign	0.04
R4812:2410089E03Rik	UTSW	15	8,201,123 (GRCm38)	splice site	probably null
R4850:2410089E03Rik	UTSW	15	8,262,938 (GRCm38)	missense	unknown
R4896:2410089E03Rik	UTSW	15	8,221,937 (GRCm38)	missense	probably benign	0.00
R5273:2410089E03Rik	UTSW	15	8,262,938 (GRCm38)	missense	unknown
R5273:2410089E03Rik	UTSW	15	8,244,341 (GRCm38)	missense	probably damaging	0.98
R5303:2410089E03Rik	UTSW	15	8,260,690 (GRCm38)	splice site	probably null
R5307:2410089E03Rik	UTSW	15	8,260,690 (GRCm38)	splice site	probably null
R5308:2410089E03Rik	UTSW	15	8,260,690 (GRCm38)	splice site	probably null
R5373:2410089E03Rik	UTSW	15	8,270,803 (GRCm38)	missense	unknown
R5374:2410089E03Rik	UTSW	15	8,270,803 (GRCm38)	missense	unknown
R5386:2410089E03Rik	UTSW	15	8,194,413 (GRCm38)	missense	probably damaging	1.00
R5534:2410089E03Rik	UTSW	15	8,228,835 (GRCm38)	missense	probably benign	0.06
R5720:2410089E03Rik	UTSW	15	8,203,687 (GRCm38)	missense	probably benign	0.35
R5891:2410089E03Rik	UTSW	15	8,188,589 (GRCm38)	missense	probably benign	0.00
R5932:2410089E03Rik	UTSW	15	8,244,595 (GRCm38)	splice site	probably null
R6053:2410089E03Rik	UTSW	15	8,188,461 (GRCm38)	missense	probably benign	0.35
R6166:2410089E03Rik	UTSW	15	8,186,560 (GRCm38)	missense	probably benign	0.00
R6245:2410089E03Rik	UTSW	15	8,178,418 (GRCm38)	missense	probably benign	0.01
R6246:2410089E03Rik	UTSW	15	8,210,014 (GRCm38)	missense	probably damaging	1.00
R6541:2410089E03Rik	UTSW	15	8,219,295 (GRCm38)	missense	possibly damaging	0.48
R6622:2410089E03Rik	UTSW	15	8,244,222 (GRCm38)	missense	probably damaging	0.98
R6707:2410089E03Rik	UTSW	15	8,223,122 (GRCm38)	missense	probably benign	0.39
R6729:2410089E03Rik	UTSW	15	8,188,601 (GRCm38)	splice site	probably null
R6805:2410089E03Rik	UTSW	15	8,244,306 (GRCm38)	missense	probably benign	0.07
R6806:2410089E03Rik	UTSW	15	8,186,858 (GRCm38)	missense	possibly damaging	0.55
R6813:2410089E03Rik	UTSW	15	8,229,282 (GRCm38)	missense	probably benign
R6830:2410089E03Rik	UTSW	15	8,176,184 (GRCm38)	missense	probably benign	0.04
R6845:2410089E03Rik	UTSW	15	8,221,904 (GRCm38)	missense	possibly damaging	0.84
R6894:2410089E03Rik	UTSW	15	8,187,368 (GRCm38)	missense	probably damaging	0.99
R6970:2410089E03Rik	UTSW	15	8,187,548 (GRCm38)	missense	probably benign	0.01
R6991:2410089E03Rik	UTSW	15	8,252,206 (GRCm38)	missense	unknown
R7003:2410089E03Rik	UTSW	15	8,228,762 (GRCm38)	missense	probably damaging	0.99
R7088:2410089E03Rik	UTSW	15	8,218,947 (GRCm38)	missense	probably benign	0.16
R7104:2410089E03Rik	UTSW	15	8,194,444 (GRCm38)	missense	possibly damaging	0.83
R7311:2410089E03Rik	UTSW	15	8,180,915 (GRCm38)	missense	probably damaging	1.00
R7374:2410089E03Rik	UTSW	15	8,247,247 (GRCm38)	missense	unknown
R7446:2410089E03Rik	UTSW	15	8,232,080 (GRCm38)	missense	probably damaging	0.98
R7539:2410089E03Rik	UTSW	15	8,201,244 (GRCm38)	missense	probably benign	0.19
R7543:2410089E03Rik	UTSW	15	8,225,392 (GRCm38)	missense	unknown
R7558:2410089E03Rik	UTSW	15	8,225,367 (GRCm38)	missense	unknown
R7629:2410089E03Rik	UTSW	15	8,227,067 (GRCm38)	nonsense	probably null
R7635:2410089E03Rik	UTSW	15	8,226,920 (GRCm38)	missense	probably benign	0.01
R7644:2410089E03Rik	UTSW	15	8,223,127 (GRCm38)	missense	probably benign	0.00
R7705:2410089E03Rik	UTSW	15	8,182,252 (GRCm38)	missense	probably damaging	1.00
R7752:2410089E03Rik	UTSW	15	8,269,706 (GRCm38)	missense	unknown
R7754:2410089E03Rik	UTSW	15	8,243,826 (GRCm38)	missense	possibly damaging	0.53
R7757:2410089E03Rik	UTSW	15	8,252,227 (GRCm38)	missense	unknown
R7836:2410089E03Rik	UTSW	15	8,203,757 (GRCm38)	missense	probably damaging	0.97
R7875:2410089E03Rik	UTSW	15	8,209,962 (GRCm38)	missense	probably benign	0.18
R7901:2410089E03Rik	UTSW	15	8,269,706 (GRCm38)	missense	unknown
R7983:2410089E03Rik	UTSW	15	8,221,815 (GRCm38)	missense	probably benign	0.01
R8030:2410089E03Rik	UTSW	15	8,230,303 (GRCm38)	missense	probably damaging	1.00
R8088:2410089E03Rik	UTSW	15	8,186,318 (GRCm38)	missense	probably benign	0.00
R8231:2410089E03Rik	UTSW	15	8,219,027 (GRCm38)	missense	probably benign	0.16
R8443:2410089E03Rik	UTSW	15	8,201,151 (GRCm38)	missense	probably benign	0.03
R8480:2410089E03Rik	UTSW	15	8,187,458 (GRCm38)	missense	possibly damaging	0.63
R8693:2410089E03Rik	UTSW	15	8,229,008 (GRCm38)	missense	probably benign	0.15
R8785:2410089E03Rik	UTSW	15	8,174,760 (GRCm38)	missense	probably benign	0.39
R8791:2410089E03Rik	UTSW	15	8,187,260 (GRCm38)	missense	probably damaging	1.00
R8822:2410089E03Rik	UTSW	15	8,171,778 (GRCm38)	missense	probably damaging	1.00
R8831:2410089E03Rik	UTSW	15	8,182,136 (GRCm38)	missense	probably benign	0.09
R8932:2410089E03Rik	UTSW	15	8,194,375 (GRCm38)	missense	probably damaging	1.00
R8973:2410089E03Rik	UTSW	15	8,203,793 (GRCm38)	missense	probably damaging	1.00
R9036:2410089E03Rik	UTSW	15	8,223,138 (GRCm38)	missense	possibly damaging	0.63
R9134:2410089E03Rik	UTSW	15	8,199,232 (GRCm38)	missense	probably damaging	0.99
R9197:2410089E03Rik	UTSW	15	8,251,052 (GRCm38)	missense	unknown
R9259:2410089E03Rik	UTSW	15	8,203,303 (GRCm38)	missense	possibly damaging	0.82
R9269:2410089E03Rik	UTSW	15	8,219,016 (GRCm38)	missense	probably damaging	0.97
R9294:2410089E03Rik	UTSW	15	8,203,327 (GRCm38)	missense	probably benign	0.00
R9328:2410089E03Rik	UTSW	15	8,186,208 (GRCm38)	missense	probably damaging	1.00
R9563:2410089E03Rik	UTSW	15	8,187,079 (GRCm38)	missense	probably benign	0.20
R9680:2410089E03Rik	UTSW	15	8,202,301 (GRCm38)	missense	possibly damaging	0.68
R9721:2410089E03Rik	UTSW	15	8,225,409 (GRCm38)	missense	unknown
R9779:2410089E03Rik	UTSW	15	8,201,302 (GRCm38)	missense	possibly damaging	0.93
R9780:2410089E03Rik	UTSW	15	8,228,639 (GRCm38)	missense	probably benign	0.00
U24488:2410089E03Rik	UTSW	15	8,182,210 (GRCm38)	missense	probably damaging	1.00
X0023:2410089E03Rik	UTSW	15	8,247,031 (GRCm38)	missense	unknown
Z1177:2410089E03Rik	UTSW	15	8,209,989 (GRCm38)	missense	probably damaging	0.98
Z1177:2410089E03Rik	UTSW	15	8,174,972 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTTGGATCTATGTATGCAATTGTGA -3'
(R):5'- GCTATTATCCAATATTTGAAGCTTGTC -3'

Sequencing Primer
(F):5'- ACAACACTCTAAGGTGGC -3'
(R):5'- AGTCAGTGCTCTTAACCGCTGAG -3'

Posted On

2021-10-11