Incidental Mutation 'R8972:Ccdc88a'
| ID |
683187 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc88a
|
| Ensembl Gene |
ENSMUSG00000032740 |
| Gene Name |
coiled coil domain containing 88A |
| Synonyms |
GIV, Girdin, D130005J21Rik, HkRP1, C330012F17Rik, C130096N06Rik, A430106J12Rik |
| MMRRC Submission |
068806-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8972 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
29323658-29460808 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 29435888 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1270
(N1270K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048978
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040182]
[ENSMUST00000140194]
[ENSMUST00000155854]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040182
AA Change: N1270K
PolyPhen 2
Score 0.074 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000048978
Gene: ENSMUSG00000032740
AA Change: N1270K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HOOK
|
14 |
590 |
8.1e-36 |
PFAM |
|
low complexity region
|
614 |
625 |
N/A |
INTRINSIC |
|
Blast:BRLZ
|
665 |
719 |
6e-22 |
BLAST |
|
low complexity region
|
826 |
839 |
N/A |
INTRINSIC |
|
low complexity region
|
883 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1093 |
1104 |
N/A |
INTRINSIC |
|
coiled coil region
|
1268 |
1385 |
N/A |
INTRINSIC |
|
low complexity region
|
1437 |
1444 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1576 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1609 |
1702 |
2.38e-6 |
PROSPERO |
|
internal_repeat_1
|
1708 |
1808 |
2.38e-6 |
PROSPERO |
|
low complexity region
|
1811 |
1824 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000123561
AA Change: N250K
PolyPhen 2
Score 0.653 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000119173
Gene: ENSMUSG00000032740
AA Change: N250K
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
212 |
N/A |
INTRINSIC |
|
coiled coil region
|
248 |
365 |
N/A |
INTRINSIC |
|
low complexity region
|
418 |
425 |
N/A |
INTRINSIC |
|
low complexity region
|
547 |
557 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140194
|
| SMART Domains |
Protein: ENSMUSP00000114942
Gene: ENSMUSG00000032740
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
3 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
144 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
304 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155854
|
| SMART Domains |
Protein: ENSMUSP00000115117
Gene: ENSMUSG00000032740
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
75 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
146 |
176 |
N/A |
INTRINSIC |
|
Blast:BRLZ
|
228 |
283 |
7e-6 |
BLAST |
|
low complexity region
|
284 |
295 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0642 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (70/71) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal weight loss, reduced angiogenesis, and premature death by P25. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
C |
T |
11: 9,278,138 (GRCm39) |
S3106F |
probably damaging |
Het |
| Acss1 |
G |
T |
2: 150,484,809 (GRCm39) |
R145S |
probably damaging |
Het |
| Acss3 |
T |
C |
10: 106,920,783 (GRCm39) |
Y109C |
probably damaging |
Het |
| Adgre4 |
G |
T |
17: 56,109,189 (GRCm39) |
G399C |
probably damaging |
Het |
| Alpk1 |
A |
G |
3: 127,473,232 (GRCm39) |
S924P |
probably damaging |
Het |
| Anapc4 |
T |
A |
5: 53,007,884 (GRCm39) |
D382E |
possibly damaging |
Het |
| Arfgef2 |
C |
T |
2: 166,709,253 (GRCm39) |
A1110V |
possibly damaging |
Het |
| Arhgap20 |
T |
C |
9: 51,760,311 (GRCm39) |
F721L |
probably benign |
Het |
| Arhgef39 |
T |
C |
4: 43,497,185 (GRCm39) |
S269G |
probably benign |
Het |
| Asap2 |
C |
T |
12: 21,279,249 (GRCm39) |
T377M |
probably damaging |
Het |
| Baiap3 |
G |
T |
17: 25,466,010 (GRCm39) |
A558E |
probably benign |
Het |
| Birc6 |
A |
C |
17: 75,009,313 (GRCm39) |
T4862P |
probably benign |
Het |
| Cc2d2a |
A |
G |
5: 43,867,884 (GRCm39) |
T843A |
probably benign |
Het |
| Ccdc187 |
A |
T |
2: 26,171,079 (GRCm39) |
D466E |
probably benign |
Het |
| Cep250 |
C |
T |
2: 155,812,042 (GRCm39) |
A446V |
unknown |
Het |
| Cntn1 |
T |
G |
15: 92,150,278 (GRCm39) |
Y371D |
probably benign |
Het |
| Cpsf1 |
T |
C |
15: 76,481,528 (GRCm39) |
D1141G |
probably damaging |
Het |
| Crebbp |
C |
T |
16: 3,925,935 (GRCm39) |
V1193I |
probably benign |
Het |
| Csf2ra |
A |
T |
19: 61,213,597 (GRCm39) |
S371T |
probably null |
Het |
| Csf2rb2 |
T |
C |
15: 78,172,115 (GRCm39) |
N432D |
probably benign |
Het |
| Cul9 |
A |
T |
17: 46,854,177 (GRCm39) |
L175Q |
probably damaging |
Het |
| Dlc1 |
T |
A |
8: 37,405,394 (GRCm39) |
R132* |
probably null |
Het |
| Dock5 |
C |
A |
14: 68,013,749 (GRCm39) |
L1324F |
probably damaging |
Het |
| Dop1a |
T |
C |
9: 86,403,300 (GRCm39) |
V36A |
possibly damaging |
Het |
| Fap |
A |
G |
2: 62,378,927 (GRCm39) |
V158A |
probably benign |
Het |
| G2e3 |
T |
A |
12: 51,410,277 (GRCm39) |
S319T |
possibly damaging |
Het |
| Gatd3a |
T |
C |
10: 78,003,323 (GRCm39) |
I110V |
possibly damaging |
Het |
| Gphn |
T |
C |
12: 78,656,013 (GRCm39) |
|
probably null |
Het |
| Gucy2g |
A |
G |
19: 55,226,406 (GRCm39) |
I170T |
probably benign |
Het |
| Hmgxb4 |
T |
A |
8: 75,748,466 (GRCm39) |
W438R |
probably damaging |
Het |
| Igkv14-126 |
G |
T |
6: 67,873,329 (GRCm39) |
G19V |
probably damaging |
Het |
| Kansl1l |
C |
T |
1: 66,812,101 (GRCm39) |
C506Y |
probably damaging |
Het |
| Kif2a |
T |
C |
13: 107,115,543 (GRCm39) |
T321A |
probably damaging |
Het |
| Krtap6-5 |
C |
T |
16: 88,844,607 (GRCm39) |
R42H |
unknown |
Het |
| Map4 |
T |
A |
9: 109,864,185 (GRCm39) |
M470K |
probably benign |
Het |
| Mill1 |
T |
C |
7: 17,996,982 (GRCm39) |
V191A |
probably benign |
Het |
| Mki67 |
C |
A |
7: 135,297,364 (GRCm39) |
A2557S |
possibly damaging |
Het |
| Mkln1 |
A |
T |
6: 31,473,681 (GRCm39) |
H669L |
probably damaging |
Het |
| Mrgprb3 |
A |
T |
7: 48,293,422 (GRCm39) |
V43E |
possibly damaging |
Het |
| Mucl2 |
T |
A |
15: 103,927,860 (GRCm39) |
|
probably null |
Het |
| Mybbp1a |
T |
A |
11: 72,337,076 (GRCm39) |
I604N |
probably benign |
Het |
| Myo18b |
T |
C |
5: 112,841,164 (GRCm39) |
T2210A |
probably benign |
Het |
| Nlrp4f |
T |
C |
13: 65,330,749 (GRCm39) |
I881M |
probably benign |
Het |
| Obscn |
C |
A |
11: 58,943,442 (GRCm39) |
A4236S |
probably benign |
Het |
| Or13a23-ps1 |
A |
T |
7: 140,119,038 (GRCm39) |
M203L |
unknown |
Het |
| Or4a67 |
A |
C |
2: 88,598,630 (GRCm39) |
F10V |
possibly damaging |
Het |
| Or8d1 |
A |
G |
9: 38,767,254 (GRCm39) |
K299E |
probably damaging |
Het |
| Or8d2b |
G |
A |
9: 38,789,150 (GRCm39) |
R226H |
probably benign |
Het |
| Phc3 |
T |
A |
3: 31,015,926 (GRCm39) |
Q83L |
possibly damaging |
Het |
| Pira2 |
T |
C |
7: 3,845,070 (GRCm39) |
Y396C |
probably damaging |
Het |
| Prss3 |
T |
A |
6: 41,353,872 (GRCm39) |
I24F |
probably damaging |
Het |
| Psg21 |
T |
C |
7: 18,381,293 (GRCm39) |
N417D |
probably benign |
Het |
| Ros1 |
G |
T |
10: 51,999,333 (GRCm39) |
R1206S |
probably benign |
Het |
| Smg9 |
A |
T |
7: 24,120,055 (GRCm39) |
Q386L |
probably benign |
Het |
| Sncb |
T |
A |
13: 54,907,772 (GRCm39) |
|
probably null |
Het |
| Son |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
16: 91,457,222 (GRCm39) |
|
probably benign |
Het |
| Sorl1 |
T |
A |
9: 41,957,848 (GRCm39) |
I599F |
probably damaging |
Het |
| Sox6 |
C |
A |
7: 115,076,218 (GRCm39) |
E807* |
probably null |
Het |
| Ssu2 |
G |
A |
6: 112,360,898 (GRCm39) |
A53V |
probably benign |
Het |
| Tas2r123 |
T |
C |
6: 132,824,333 (GRCm39) |
C77R |
probably benign |
Het |
| Tcta |
T |
C |
9: 108,181,333 (GRCm39) |
R117G |
unknown |
Het |
| Tiam1 |
G |
A |
16: 89,609,894 (GRCm39) |
A1038V |
probably damaging |
Het |
| Tram2 |
A |
T |
1: 21,074,273 (GRCm39) |
|
probably benign |
Het |
| Tsku |
C |
A |
7: 98,001,704 (GRCm39) |
R209L |
probably damaging |
Het |
| Twnk |
T |
C |
19: 45,000,149 (GRCm39) |
F622L |
probably damaging |
Het |
| Ube2t |
C |
T |
1: 134,899,670 (GRCm39) |
T106I |
probably damaging |
Het |
| Usf1 |
C |
T |
1: 171,245,352 (GRCm39) |
R255W |
probably damaging |
Het |
| Usp28 |
T |
A |
9: 48,949,124 (GRCm39) |
L906Q |
probably null |
Het |
| Vmn2r31 |
T |
A |
7: 7,399,654 (GRCm39) |
Y101F |
probably benign |
Het |
| Vmn2r42 |
A |
G |
7: 8,187,331 (GRCm39) |
S814P |
probably damaging |
Het |
| Wnt2b |
T |
C |
3: 104,858,475 (GRCm39) |
R265G |
possibly damaging |
Het |
| Zfp62 |
T |
G |
11: 49,106,892 (GRCm39) |
S328A |
possibly damaging |
Het |
| Zfp974 |
T |
C |
7: 27,610,589 (GRCm39) |
I379V |
probably benign |
Het |
| Zmynd15 |
T |
C |
11: 70,355,065 (GRCm39) |
V484A |
possibly damaging |
Het |
| Zzef1 |
T |
C |
11: 72,791,499 (GRCm39) |
L2201P |
probably damaging |
Het |
|
| Other mutations in Ccdc88a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00499:Ccdc88a
|
APN |
11 |
29,449,341 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL00577:Ccdc88a
|
APN |
11 |
29,374,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00766:Ccdc88a
|
APN |
11 |
29,451,046 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01384:Ccdc88a
|
APN |
11 |
29,453,915 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01541:Ccdc88a
|
APN |
11 |
29,350,283 (GRCm39) |
missense |
probably benign |
|
|
IGL01647:Ccdc88a
|
APN |
11 |
29,454,321 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02648:Ccdc88a
|
APN |
11 |
29,451,051 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02885:Ccdc88a
|
APN |
11 |
29,398,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03117:Ccdc88a
|
APN |
11 |
29,324,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03196:Ccdc88a
|
APN |
11 |
29,432,340 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
trailor
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0108:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0326:Ccdc88a
|
UTSW |
11 |
29,411,021 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0565:Ccdc88a
|
UTSW |
11 |
29,411,042 (GRCm39) |
unclassified |
probably benign |
|
|
R0631:Ccdc88a
|
UTSW |
11 |
29,443,752 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Ccdc88a
|
UTSW |
11 |
29,432,749 (GRCm39) |
unclassified |
probably benign |
|
|
R0762:Ccdc88a
|
UTSW |
11 |
29,413,112 (GRCm39) |
unclassified |
probably benign |
|
|
R0838:Ccdc88a
|
UTSW |
11 |
29,350,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0946:Ccdc88a
|
UTSW |
11 |
29,406,509 (GRCm39) |
missense |
probably benign |
|
|
R1192:Ccdc88a
|
UTSW |
11 |
29,454,049 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R1500:Ccdc88a
|
UTSW |
11 |
29,432,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1701:Ccdc88a
|
UTSW |
11 |
29,427,427 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1826:Ccdc88a
|
UTSW |
11 |
29,439,637 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1902:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1903:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2021:Ccdc88a
|
UTSW |
11 |
29,453,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2023:Ccdc88a
|
UTSW |
11 |
29,413,546 (GRCm39) |
nonsense |
probably null |
|
|
R2284:Ccdc88a
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R3236:Ccdc88a
|
UTSW |
11 |
29,397,995 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R3409:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3410:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3411:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3430:Ccdc88a
|
UTSW |
11 |
29,398,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3620:Ccdc88a
|
UTSW |
11 |
29,380,227 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4204:Ccdc88a
|
UTSW |
11 |
29,413,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4515:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4518:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4519:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4693:Ccdc88a
|
UTSW |
11 |
29,432,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Ccdc88a
|
UTSW |
11 |
29,372,586 (GRCm39) |
missense |
probably benign |
|
|
R4707:Ccdc88a
|
UTSW |
11 |
29,397,956 (GRCm39) |
missense |
probably benign |
|
|
R4732:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4733:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4734:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4749:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4817:Ccdc88a
|
UTSW |
11 |
29,410,907 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4828:Ccdc88a
|
UTSW |
11 |
29,413,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ccdc88a
|
UTSW |
11 |
29,432,133 (GRCm39) |
nonsense |
probably null |
|
|
R5288:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5373:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5374:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5401:Ccdc88a
|
UTSW |
11 |
29,413,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5586:Ccdc88a
|
UTSW |
11 |
29,453,484 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ccdc88a
|
UTSW |
11 |
29,432,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7116:Ccdc88a
|
UTSW |
11 |
29,454,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7353:Ccdc88a
|
UTSW |
11 |
29,413,368 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7538:Ccdc88a
|
UTSW |
11 |
29,413,370 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7663:Ccdc88a
|
UTSW |
11 |
29,448,614 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7769:Ccdc88a
|
UTSW |
11 |
29,432,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Ccdc88a
|
UTSW |
11 |
29,427,348 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7810:Ccdc88a
|
UTSW |
11 |
29,435,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7826:Ccdc88a
|
UTSW |
11 |
29,453,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7956:Ccdc88a
|
UTSW |
11 |
29,413,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Ccdc88a
|
UTSW |
11 |
29,443,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8402:Ccdc88a
|
UTSW |
11 |
29,413,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8409:Ccdc88a
|
UTSW |
11 |
29,453,544 (GRCm39) |
missense |
probably benign |
|
|
R8555:Ccdc88a
|
UTSW |
11 |
29,380,169 (GRCm39) |
missense |
probably benign |
|
|
R8676:Ccdc88a
|
UTSW |
11 |
29,410,860 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8846:Ccdc88a
|
UTSW |
11 |
29,414,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9353:Ccdc88a
|
UTSW |
11 |
29,427,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Ccdc88a
|
UTSW |
11 |
29,453,922 (GRCm39) |
missense |
probably null |
0.55 |
|
R9385:Ccdc88a
|
UTSW |
11 |
29,405,422 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9509:Ccdc88a
|
UTSW |
11 |
29,414,143 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9610:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9611:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9664:Ccdc88a
|
UTSW |
11 |
29,405,484 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9720:Ccdc88a
|
UTSW |
11 |
29,413,813 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTTAATACCAGGTTGATTGAGTCAC -3'
(R):5'- TAGGCATGTCTTGACATAAAGGAAG -3'
Sequencing Primer
(F):5'- GGCTTACACGTTCAGAGGTTCAATC -3'
(R):5'- GAAACAATGATGAAGTCTGTTGACAC -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation