Mutagenetix > Incidental Mutation

Incidental Mutation 'R8975:Efcab3'

683400

Institutional Source

Beutler Lab

Gene Symbol

Efcab3

Ensembl Gene

ENSMUSG00000020690

Gene Name

EF-hand calcium binding domain 3

Synonyms

Gm11639, Efcab13, 4921510J17Rik, Efcab15, Gm11639

MMRRC Submission

068809-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8975 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

104954418-105008363 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 104954415 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Glutamic Acid at position 5090 (K5090E)

Ref Sequence

ENSEMBL: ENSMUSP00000148433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000136876] [ENSMUST00000137086] [ENSMUST00000212287]

AlphaFold

Q80X60

Predicted Effect

probably benign
Transcript: ENSMUST00000136876

SMART Domains

Protein: ENSMUSP00000120875
Gene: ENSMUSG00000020690

Domain	Start	End	E-Value	Type
SCOP:d1exra_	2	127	2e-3	SMART
Blast:EFh	102	130	8e-12	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000137086

SMART Domains

Protein: ENSMUSP00000114580
Gene: ENSMUSG00000020690

Domain	Start	End	E-Value	Type
internal_repeat_1	4	78	5.46e-7	PROSPERO
EFh	102	130	2.18e1	SMART
EFh	155	183	4.93e0	SMART
Blast:EFh	257	285	3e-7	BLAST
EFh	293	321	1.03e0	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000212287
AA Change: K5090E

PolyPhen 2 Score 0.168 (Sensitivity: 0.92; Specificity: 0.87)

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (64/64)

Allele List at MGI

Other mutations in this stock

Total: 65 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700018F24Rik	A	G	5: 144,980,192 (GRCm39)	D47G	probably damaging	Het
4930550C14Rik	A	T	9: 53,334,258 (GRCm39)	K167M	possibly damaging	Het
Abhd16b	A	G	2: 181,135,806 (GRCm39)	N236S	probably benign	Het
Ahnak	T	G	19: 8,990,101 (GRCm39)	V3795G	probably damaging	Het
Atg2b	A	T	12: 105,602,725 (GRCm39)	M1606K	probably damaging	Het
Bmt2	A	T	6: 13,630,611 (GRCm39)	I187K	probably damaging	Het
Cep250	C	T	2: 155,812,042 (GRCm39)	A446V	unknown	Het
Cep290	A	G	10: 100,349,782 (GRCm39)	N610D	possibly damaging	Het
Ctps1	C	T	4: 120,406,743 (GRCm39)	D338N	probably benign	Het
Ctsz	A	T	2: 174,275,421 (GRCm39)	I118N	probably benign	Het
Depdc1b	A	G	13: 108,525,094 (GRCm39)	E483G	probably null	Het
Dhh	T	C	15: 98,795,976 (GRCm39)	S60G	probably damaging	Het
Dpagt1	T	C	9: 44,237,446 (GRCm39)		probably benign	Het
Dpy19l1	T	C	9: 24,359,102 (GRCm39)	K162R	probably damaging	Het
Dynap	T	C	18: 70,375,093 (GRCm39)	T41A	possibly damaging	Het
Dyrk4	T	C	6: 126,871,783 (GRCm39)	N162D	probably benign	Het
Eml5	T	A	12: 98,776,829 (GRCm39)	T1429S	probably damaging	Het
Fbn2	C	T	18: 58,286,928 (GRCm39)	G244R	probably damaging	Het
Fer1l5	A	G	1: 36,456,897 (GRCm39)	D1625G	probably benign	Het
Frmd4b	G	A	6: 97,283,477 (GRCm39)	T484M	possibly damaging	Het
Hhat	T	C	1: 192,431,250 (GRCm39)	E33G	probably damaging	Het
Ifngr1	A	G	10: 19,485,360 (GRCm39)	D453G	probably damaging	Het
Itpr3	T	A	17: 27,335,628 (GRCm39)	I2246N	possibly damaging	Het
Larp4b	T	G	13: 9,195,537 (GRCm39)	I212S	probably damaging	Het
Lilra5	T	C	7: 4,241,636 (GRCm39)	V145A	probably benign	Het
Map1lc3a	A	G	2: 155,118,926 (GRCm39)	K30R	possibly damaging	Het
Mapk8ip1	A	G	2: 92,215,166 (GRCm39)	Y652H	probably damaging	Het
Med23	A	G	10: 24,780,334 (GRCm39)	E994G	probably benign	Het
Mep1b	A	T	18: 21,208,714 (GRCm39)	D30V	probably benign	Het
Mki67	C	A	7: 135,297,364 (GRCm39)	A2557S	possibly damaging	Het
Mki67	T	C	7: 135,300,129 (GRCm39)	D1635G	probably benign	Het
Msantd5f6	A	G	4: 73,320,167 (GRCm39)	L204P	probably damaging	Het
Mup3	A	T	4: 62,003,472 (GRCm39)	D132E	probably benign	Het
Myo15b	A	T	11: 115,781,780 (GRCm39)	T2830S	unknown	Het
Myocd	T	A	11: 65,069,287 (GRCm39)	H979L	probably damaging	Het
Nvl	A	T	1: 180,958,001 (GRCm39)	N260K	probably benign	Het
Or2a57	T	A	6: 43,213,056 (GRCm39)	H171Q	probably benign	Het
Or2d2b	T	A	7: 106,705,664 (GRCm39)	T135S	probably benign	Het
Or4d2	T	A	11: 87,784,645 (GRCm39)	Y35F	probably damaging	Het
Pdha2	C	A	3: 140,917,649 (GRCm39)		probably benign	Het
Peg10	GC	GCTCC	6: 4,756,452 (GRCm39)		probably benign	Het
Phtf2	A	C	5: 20,969,249 (GRCm39)	V687G	probably damaging	Het
Plagl2	C	T	2: 153,074,346 (GRCm39)	G185D	possibly damaging	Het
Ppp1r3e	A	G	14: 55,113,946 (GRCm39)	V242A	probably benign	Het
Proser3	A	G	7: 30,239,458 (GRCm39)	S549P	possibly damaging	Het
Prrc2c	A	G	1: 162,533,630 (GRCm39)	V995A	unknown	Het
Ptpn13	A	G	5: 103,649,266 (GRCm39)	H223R	probably benign	Het
Rsf1	CG	CGTCGGCGGGG	7: 97,229,115 (GRCm39)		probably benign	Het
Scn11a	T	C	9: 119,587,565 (GRCm39)	E1393G	probably damaging	Het
Sipa1l1	T	A	12: 82,479,612 (GRCm39)	S1432T	possibly damaging	Het
Slc10a5	G	C	3: 10,399,670 (GRCm39)	A330G	probably benign	Het
Slc2a5	A	C	4: 150,224,270 (GRCm39)	N293H	probably damaging	Het
Spmap1	A	T	11: 97,663,572 (GRCm39)	Y93N	probably damaging	Het
Spmip4	C	T	6: 50,561,391 (GRCm39)	R176H	probably damaging	Het
Sptbn1	T	C	11: 30,073,869 (GRCm39)	E1400G	possibly damaging	Het
Stk33	T	A	7: 108,935,280 (GRCm39)	I171F	probably damaging	Het
Syne1	G	A	10: 5,161,945 (GRCm39)	H5450Y	probably benign	Het
Tbcd	G	C	11: 121,387,679 (GRCm39)		probably benign	Het
Tkt	T	A	14: 30,288,884 (GRCm39)		probably benign	Het
Tpra1	A	T	6: 88,888,726 (GRCm39)	M303L	probably benign	Het
Ubr3	T	C	2: 69,752,651 (GRCm39)	S303P	probably damaging	Het
Uqcrc1	T	C	9: 108,776,721 (GRCm39)	F341S	probably damaging	Het
Vmn1r223	T	C	13: 23,434,248 (GRCm39)	S281P	possibly damaging	Het
Vmn1r32	C	A	6: 66,530,189 (GRCm39)	A196S	probably benign	Het
Zfp644	G	T	5: 106,785,467 (GRCm39)	T360N	probably benign	Het

Other mutations in Efcab3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00897:Efcab3	APN	11	104,990,847 (GRCm39)	missense	probably damaging	1.00
IGL01308:Efcab3	APN	11	104,611,523 (GRCm39)	missense	probably benign	0.03
IGL01483:Efcab3	APN	11	104,630,173 (GRCm39)	missense	probably benign	0.03
IGL01695:Efcab3	APN	11	104,626,889 (GRCm39)	missense	probably damaging	1.00
IGL01860:Efcab3	APN	11	104,581,747 (GRCm39)	missense	probably benign	0.16
IGL01981:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL01984:Efcab3	APN	11	104,629,134 (GRCm39)	missense	probably benign	0.20
IGL02023:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL02252:Efcab3	APN	11	104,644,753 (GRCm39)	missense	possibly damaging	0.68
IGL02886:Efcab3	APN	11	104,986,700 (GRCm39)	missense	possibly damaging	0.95
IGL03116:Efcab3	APN	11	104,612,359 (GRCm39)	missense	probably benign	0.02
IGL03141:Efcab3	APN	11	104,986,696 (GRCm39)	missense	probably damaging	0.99
IGL03242:Efcab3	APN	11	104,997,230 (GRCm39)	missense	probably damaging	1.00
IGL03274:Efcab3	APN	11	104,611,919 (GRCm39)	missense	probably benign	0.03
IGL03408:Efcab3	APN	11	104,601,447 (GRCm39)	missense	probably benign	0.03
PIT4812001:Efcab3	UTSW	11	104,990,805 (GRCm39)	missense	probably null	0.00
R0018:Efcab3	UTSW	11	104,612,378 (GRCm39)	critical splice donor site	probably null
R0068:Efcab3	UTSW	11	104,611,648 (GRCm39)	missense	probably benign	0.29
R0350:Efcab3	UTSW	11	104,581,706 (GRCm39)	missense	probably benign	0.03
R0388:Efcab3	UTSW	11	105,000,227 (GRCm39)	missense	possibly damaging	0.61
R0646:Efcab3	UTSW	11	104,611,327 (GRCm39)	missense	probably benign	0.03
R0668:Efcab3	UTSW	11	104,611,318 (GRCm39)	missense	probably benign	0.16
R0715:Efcab3	UTSW	11	104,611,706 (GRCm39)	missense	possibly damaging	0.90
R0944:Efcab3	UTSW	11	104,601,556 (GRCm39)	splice site	probably null
R1330:Efcab3	UTSW	11	104,637,116 (GRCm39)	missense	possibly damaging	0.84
R1440:Efcab3	UTSW	11	104,999,581 (GRCm39)	splice site	probably benign
R1508:Efcab3	UTSW	11	104,601,503 (GRCm39)	missense	probably benign	0.03
R1540:Efcab3	UTSW	11	104,999,726 (GRCm39)	missense	probably benign	0.07
R1643:Efcab3	UTSW	11	104,589,804 (GRCm39)	missense	probably benign	0.16
R1651:Efcab3	UTSW	11	104,611,492 (GRCm39)	missense	probably benign	0.03
R1665:Efcab3	UTSW	11	104,611,940 (GRCm39)	missense	probably benign	0.07
R1702:Efcab3	UTSW	11	104,581,832 (GRCm39)	missense	probably benign	0.03
R1711:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1779:Efcab3	UTSW	11	104,611,765 (GRCm39)	missense	probably benign	0.15
R1813:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1818:Efcab3	UTSW	11	104,612,333 (GRCm39)	missense	probably benign	0.10
R1896:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1969:Efcab3	UTSW	11	104,637,090 (GRCm39)	missense	probably damaging	1.00
R2029:Efcab3	UTSW	11	104,990,851 (GRCm39)	missense	probably damaging	0.99
R2139:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R2165:Efcab3	UTSW	11	104,642,688 (GRCm39)	missense	possibly damaging	0.93
R2359:Efcab3	UTSW	11	104,630,106 (GRCm39)	missense	possibly damaging	0.80
R2394:Efcab3	UTSW	11	104,629,121 (GRCm39)	missense	probably benign	0.17
R2401:Efcab3	UTSW	11	104,963,144 (GRCm39)	critical splice donor site	probably null
R2406:Efcab3	UTSW	11	104,611,457 (GRCm39)	missense	probably benign	0.03
R2570:Efcab3	UTSW	11	104,624,490 (GRCm39)	missense	probably damaging	1.00
R3795:Efcab3	UTSW	11	104,624,501 (GRCm39)	missense	possibly damaging	0.94
R3901:Efcab3	UTSW	11	104,974,713 (GRCm39)	missense	possibly damaging	0.68
R4244:Efcab3	UTSW	11	105,002,629 (GRCm39)	missense	probably damaging	1.00
R4352:Efcab3	UTSW	11	104,630,140 (GRCm39)	missense	probably null	0.25
R4359:Efcab3	UTSW	11	104,624,547 (GRCm39)	splice site	probably null
R4424:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably null
R4895:Efcab3	UTSW	11	105,008,227 (GRCm39)	unclassified	probably benign
R4895:Efcab3	UTSW	11	104,640,496 (GRCm39)	missense	probably damaging	1.00
R4895:Efcab3	UTSW	11	104,611,112 (GRCm39)	missense	probably benign	0.16
R5006:Efcab3	UTSW	11	104,620,503 (GRCm39)	splice site	probably null
R5066:Efcab3	UTSW	11	104,611,490 (GRCm39)	missense	probably benign	0.03
R5316:Efcab3	UTSW	11	104,967,286 (GRCm39)	missense	possibly damaging	0.80
R5329:Efcab3	UTSW	11	104,644,632 (GRCm39)	splice site	probably null
R5405:Efcab3	UTSW	11	104,612,018 (GRCm39)	missense	probably benign	0.07
R5814:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably benign
R5888:Efcab3	UTSW	11	104,612,227 (GRCm39)	splice site	probably benign
R5910:Efcab3	UTSW	11	104,581,760 (GRCm39)	missense	probably benign	0.01
R5975:Efcab3	UTSW	11	104,578,375 (GRCm39)	start gained	probably benign
R6019:Efcab3	UTSW	11	104,933,728 (GRCm39)	critical splice donor site	probably null
R6028:Efcab3	UTSW	11	104,660,481 (GRCm39)	critical splice donor site	probably null
R6048:Efcab3	UTSW	11	104,835,259 (GRCm39)	missense	unknown
R6059:Efcab3	UTSW	11	104,927,595 (GRCm39)	missense	probably benign	0.03
R6147:Efcab3	UTSW	11	104,858,566 (GRCm39)	missense	unknown
R6176:Efcab3	UTSW	11	104,683,383 (GRCm39)	missense	probably benign	0.16
R6181:Efcab3	UTSW	11	104,722,159 (GRCm39)	missense	probably benign	0.25
R6196:Efcab3	UTSW	11	104,746,386 (GRCm39)	missense	probably benign	0.07
R6245:Efcab3	UTSW	11	104,675,834 (GRCm39)	missense	probably benign	0.03
R6262:Efcab3	UTSW	11	104,784,579 (GRCm39)	missense	probably benign	0.24
R6263:Efcab3	UTSW	11	104,810,312 (GRCm39)	missense	unknown
R6277:Efcab3	UTSW	11	104,901,148 (GRCm39)	missense	possibly damaging	0.49
R6338:Efcab3	UTSW	11	104,734,034 (GRCm39)	nonsense	probably null
R6355:Efcab3	UTSW	11	104,896,511 (GRCm39)	missense	probably benign	0.29
R6356:Efcab3	UTSW	11	104,784,533 (GRCm39)	missense	probably benign	0.19
R6365:Efcab3	UTSW	11	104,815,412 (GRCm39)	missense	unknown
R6378:Efcab3	UTSW	11	104,999,620 (GRCm39)	missense	possibly damaging	0.83
R6391:Efcab3	UTSW	11	104,885,143 (GRCm39)	missense	possibly damaging	0.92
R6494:Efcab3	UTSW	11	104,990,845 (GRCm39)	missense	possibly damaging	0.93
R6556:Efcab3	UTSW	11	104,899,077 (GRCm39)	missense	probably null	0.03
R6573:Efcab3	UTSW	11	104,971,461 (GRCm39)	missense	possibly damaging	0.91
R6604:Efcab3	UTSW	11	104,589,772 (GRCm39)	nonsense	probably null
R6605:Efcab3	UTSW	11	104,890,107 (GRCm39)	splice site	probably null
R6634:Efcab3	UTSW	11	104,784,609 (GRCm39)	missense	probably benign	0.17
R6723:Efcab3	UTSW	11	105,007,906 (GRCm39)	missense	possibly damaging	0.95
R6851:Efcab3	UTSW	11	104,896,521 (GRCm39)	missense	probably benign	0.03
R6862:Efcab3	UTSW	11	104,612,284 (GRCm39)	nonsense	probably null
R6949:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	1.00
R6970:Efcab3	UTSW	11	104,667,182 (GRCm39)	missense	probably benign	0.03
R7014:Efcab3	UTSW	11	104,584,248 (GRCm39)	missense	probably benign	0.03
R7097:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7122:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7124:Efcab3	UTSW	11	104,629,100 (GRCm39)	missense	probably benign	0.17
R7146:Efcab3	UTSW	11	104,913,764 (GRCm39)	missense	probably benign	0.03
R7146:Efcab3	UTSW	11	104,858,578 (GRCm39)	missense	unknown
R7154:Efcab3	UTSW	11	104,589,966 (GRCm39)	splice site	probably null
R7175:Efcab3	UTSW	11	104,838,237 (GRCm39)	missense	unknown
R7189:Efcab3	UTSW	11	104,986,690 (GRCm39)	missense	probably benign
R7198:Efcab3	UTSW	11	104,642,711 (GRCm39)	missense	probably benign	0.15
R7211:Efcab3	UTSW	11	104,601,539 (GRCm39)	missense	probably benign	0.01
R7211:Efcab3	UTSW	11	104,615,435 (GRCm39)	critical splice donor site	probably null
R7216:Efcab3	UTSW	11	104,771,375 (GRCm39)	missense	possibly damaging	0.49
R7221:Efcab3	UTSW	11	104,791,432 (GRCm39)	missense	probably benign	0.36
R7233:Efcab3	UTSW	11	104,730,669 (GRCm39)	missense	possibly damaging	0.69
R7236:Efcab3	UTSW	11	104,790,093 (GRCm39)	missense	probably benign	0.10
R7262:Efcab3	UTSW	11	104,745,432 (GRCm39)	critical splice donor site	probably null
R7289:Efcab3	UTSW	11	104,929,184 (GRCm39)	missense	probably benign	0.24
R7323:Efcab3	UTSW	11	104,920,837 (GRCm39)	missense	probably benign	0.07
R7378:Efcab3	UTSW	11	104,605,528 (GRCm39)	missense	probably benign	0.03
R7388:Efcab3	UTSW	11	104,611,871 (GRCm39)	missense	probably damaging	0.97
R7390:Efcab3	UTSW	11	104,615,411 (GRCm39)	missense	possibly damaging	0.46
R7411:Efcab3	UTSW	11	104,890,549 (GRCm39)	missense	probably benign	0.10
R7468:Efcab3	UTSW	11	104,640,526 (GRCm39)	missense	probably benign	0.17
R7483:Efcab3	UTSW	11	105,000,112 (GRCm39)	missense	probably benign	0.39
R7497:Efcab3	UTSW	11	104,653,516 (GRCm39)	critical splice donor site	probably null
R7612:Efcab3	UTSW	11	104,999,647 (GRCm39)	missense	possibly damaging	0.80
R7620:Efcab3	UTSW	11	104,722,969 (GRCm39)	missense	possibly damaging	0.95
R7638:Efcab3	UTSW	11	104,927,625 (GRCm39)	missense	probably benign	0.03
R7661:Efcab3	UTSW	11	104,617,503 (GRCm39)	missense	probably benign	0.03
R7667:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R7682:Efcab3	UTSW	11	104,855,174 (GRCm39)	splice site	probably null
R7708:Efcab3	UTSW	11	104,855,397 (GRCm39)	missense	unknown
R7719:Efcab3	UTSW	11	105,002,674 (GRCm39)	missense	probably benign	0.14
R7721:Efcab3	UTSW	11	104,615,366 (GRCm39)	nonsense	probably null
R7735:Efcab3	UTSW	11	104,962,465 (GRCm39)	missense	probably benign
R7747:Efcab3	UTSW	11	104,733,429 (GRCm39)	missense	probably damaging	0.96
R7840:Efcab3	UTSW	11	104,624,539 (GRCm39)	missense	probably benign	0.07
R7846:Efcab3	UTSW	11	104,605,571 (GRCm39)	critical splice donor site	probably null
R7893:Efcab3	UTSW	11	104,870,186 (GRCm39)	missense	unknown
R7895:Efcab3	UTSW	11	105,008,150 (GRCm39)	missense	probably benign	0.29
R7897:Efcab3	UTSW	11	104,889,061 (GRCm39)	missense	probably benign	0.24
R7936:Efcab3	UTSW	11	104,890,524 (GRCm39)	missense	possibly damaging	0.89
R7936:Efcab3	UTSW	11	104,937,385 (GRCm39)	critical splice donor site	probably null
R7959:Efcab3	UTSW	11	104,933,627 (GRCm39)	missense	probably damaging	0.96
R8031:Efcab3	UTSW	11	104,772,295 (GRCm39)	missense	possibly damaging	0.49
R8041:Efcab3	UTSW	11	104,810,305 (GRCm39)	missense	unknown
R8054:Efcab3	UTSW	11	104,621,226 (GRCm39)	missense	probably benign	0.07
R8056:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	0.98
R8061:Efcab3	UTSW	11	104,997,275 (GRCm39)	missense	probably benign	0.00
R8088:Efcab3	UTSW	11	104,889,072 (GRCm39)	missense	probably benign	0.10
R8112:Efcab3	UTSW	11	104,841,026 (GRCm39)	missense	unknown
R8116:Efcab3	UTSW	11	105,002,677 (GRCm39)	missense	possibly damaging	0.65
R8340:Efcab3	UTSW	11	104,876,856 (GRCm39)	missense	unknown
R8405:Efcab3	UTSW	11	104,612,024 (GRCm39)	missense	probably benign	0.02
R8413:Efcab3	UTSW	11	104,811,135 (GRCm39)	missense	unknown
R8472:Efcab3	UTSW	11	104,709,463 (GRCm39)	missense	probably benign	0.07
R8549:Efcab3	UTSW	11	104,890,521 (GRCm39)	missense	probably damaging	0.99
R8699:Efcab3	UTSW	11	104,672,072 (GRCm39)	missense	probably benign	0.03
R8711:Efcab3	UTSW	11	104,743,371 (GRCm39)	missense	probably benign	0.03
R8732:Efcab3	UTSW	11	104,695,100 (GRCm39)	missense	probably benign	0.03
R8745:Efcab3	UTSW	11	104,749,304 (GRCm39)	missense	possibly damaging	0.57
R8806:Efcab3	UTSW	11	104,928,695 (GRCm39)	missense	probably benign	0.07
R8810:Efcab3	UTSW	11	104,805,721 (GRCm39)	missense	unknown
R8845:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R8870:Efcab3	UTSW	11	104,791,500 (GRCm39)	missense	probably benign	0.07
R8872:Efcab3	UTSW	11	104,760,880 (GRCm39)	missense	probably benign	0.19
R8879:Efcab3	UTSW	11	104,581,781 (GRCm39)	missense	probably benign	0.03
R8924:Efcab3	UTSW	11	104,806,253 (GRCm39)	frame shift	probably null
R8954:Efcab3	UTSW	11	104,909,525 (GRCm39)	critical splice donor site	probably null
R8960:Efcab3	UTSW	11	104,820,772 (GRCm39)	splice site	probably benign
R8988:Efcab3	UTSW	11	104,911,352 (GRCm39)	missense	probably benign	0.07
R8998:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R8999:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R9002:Efcab3	UTSW	11	104,920,822 (GRCm39)	missense	probably damaging	0.99
R9012:Efcab3	UTSW	11	104,711,347 (GRCm39)	critical splice donor site	probably null
R9036:Efcab3	UTSW	11	104,927,601 (GRCm39)	missense	probably benign	0.03
R9037:Efcab3	UTSW	11	104,803,791 (GRCm39)	missense	unknown
R9059:Efcab3	UTSW	11	104,642,689 (GRCm39)	missense	possibly damaging	0.73
R9066:Efcab3	UTSW	11	104,631,688 (GRCm39)	intron	probably benign
R9122:Efcab3	UTSW	11	104,856,605 (GRCm39)	missense	unknown
R9125:Efcab3	UTSW	11	104,736,360 (GRCm39)	missense	probably damaging	1.00
R9127:Efcab3	UTSW	11	104,741,407 (GRCm39)	missense	probably benign	0.07
R9171:Efcab3	UTSW	11	104,800,708 (GRCm39)	missense	probably benign	0.36
R9219:Efcab3	UTSW	11	104,836,691 (GRCm39)	missense	unknown
R9224:Efcab3	UTSW	11	104,661,801 (GRCm39)	missense	probably benign	0.07
R9235:Efcab3	UTSW	11	104,907,987 (GRCm39)	missense	probably benign	0.19
R9294:Efcab3	UTSW	11	104,722,126 (GRCm39)	missense	probably benign	0.24
R9318:Efcab3	UTSW	11	104,856,648 (GRCm39)	critical splice donor site	probably null
R9322:Efcab3	UTSW	11	104,765,199 (GRCm39)	missense	probably benign	0.36
R9361:Efcab3	UTSW	11	104,896,524 (GRCm39)	missense	probably benign	0.03
R9408:Efcab3	UTSW	11	104,621,255 (GRCm39)	critical splice donor site	probably null
R9434:Efcab3	UTSW	11	104,899,863 (GRCm39)	missense	probably benign	0.24
R9477:Efcab3	UTSW	11	104,836,698 (GRCm39)	missense	unknown
R9658:Efcab3	UTSW	11	104,611,120 (GRCm39)	missense	probably benign	0.03
R9719:Efcab3	UTSW	11	104,867,912 (GRCm39)	missense	unknown
R9751:Efcab3	UTSW	11	104,783,911 (GRCm39)	missense	probably benign	0.19
R9763:Efcab3	UTSW	11	104,890,485 (GRCm39)	missense	possibly damaging	0.89
X0026:Efcab3	UTSW	11	105,007,937 (GRCm39)	missense	probably benign	0.03
X0026:Efcab3	UTSW	11	104,611,801 (GRCm39)	missense	probably benign	0.07
Z1088:Efcab3	UTSW	11	104,642,728 (GRCm39)	missense	probably damaging	0.96
Z1176:Efcab3	UTSW	11	104,990,872 (GRCm39)	missense	probably damaging	1.00
Z1176:Efcab3	UTSW	11	104,892,793 (GRCm39)	missense	probably benign	0.29
Z1176:Efcab3	UTSW	11	104,999,598 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,711,344 (GRCm39)	missense	probably benign	0.03
Z1177:Efcab3	UTSW	11	104,630,164 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,814,845 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- TCCTCTTACCTGACTTAGAAAAGGC -3'
(R):5'- TCCACAGGAGTTCGCAGTTC -3'

Sequencing Primer
(F):5'- CCTGACTTAGAAAAGGCTTTCAG -3'
(R):5'- CTCTTCTTCTTCTTTTTCCTTAGCAG -3'

Posted On

2021-10-11