Incidental Mutation 'R8989:Insrr'
| ID |
684270 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Insrr
|
| Ensembl Gene |
ENSMUSG00000005640 |
| Gene Name |
insulin receptor-related receptor |
| Synonyms |
|
| MMRRC Submission |
068821-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.274)
|
| Stock # |
R8989 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87704258-87723408 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 87722664 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1295
(N1295K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000029711
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029711]
[ENSMUST00000029714]
[ENSMUST00000090981]
[ENSMUST00000107582]
|
| AlphaFold |
Q9WTL4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029711
AA Change: N1295K
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000029711
Gene: ENSMUSG00000005640
AA Change: N1295K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
1.8e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
3.8e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029714
|
| SMART Domains |
Protein: ENSMUSP00000029714
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000090981
|
| SMART Domains |
Protein: ENSMUSP00000088503
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107582
AA Change: N1295K
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000103208
Gene: ENSMUSG00000005640
AA Change: N1295K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
7.7e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
1.6e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Meta Mutation Damage Score |
0.0662 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.4%
|
| Validation Efficiency |
100% (62/62) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no anomalies in pancreatic islet morphology, beta-cell mass or pancreatic secretory function. This mutation in combination with Insr mutant mice does not affect the diabetes predisposition of Insr mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 62 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
A |
G |
13: 77,760,724 (GRCm39) |
I1260M |
probably benign |
Het |
| A1cf |
T |
A |
19: 31,904,556 (GRCm39) |
F273Y |
possibly damaging |
Het |
| A3galt2 |
T |
C |
4: 128,655,231 (GRCm39) |
W45R |
probably damaging |
Het |
| Adam23 |
A |
G |
1: 63,588,948 (GRCm39) |
E460G |
probably damaging |
Het |
| Ago1 |
T |
A |
4: 126,357,583 (GRCm39) |
T31S |
probably benign |
Het |
| Ago3 |
T |
A |
4: 126,298,191 (GRCm39) |
T110S |
probably damaging |
Het |
| Akap6 |
T |
C |
12: 52,927,654 (GRCm39) |
F188S |
probably damaging |
Het |
| Asic2 |
G |
A |
11: 81,043,180 (GRCm39) |
P38S |
probably benign |
Het |
| Astn2 |
A |
T |
4: 65,499,890 (GRCm39) |
C1000S |
possibly damaging |
Het |
| Atp10b |
T |
A |
11: 43,136,269 (GRCm39) |
C1132* |
probably null |
Het |
| Atp7b |
A |
T |
8: 22,510,911 (GRCm39) |
S527T |
probably benign |
Het |
| Bod1l |
G |
A |
5: 41,979,025 (GRCm39) |
T763I |
probably benign |
Het |
| Capn11 |
A |
G |
17: 45,954,783 (GRCm39) |
L118P |
probably damaging |
Het |
| Col13a1 |
T |
C |
10: 61,696,250 (GRCm39) |
E589G |
unknown |
Het |
| Col6a2 |
T |
C |
10: 76,440,015 (GRCm39) |
D630G |
probably damaging |
Het |
| Ctnnd2 |
G |
A |
15: 30,669,660 (GRCm39) |
R423H |
probably damaging |
Het |
| Dld |
G |
A |
12: 31,383,458 (GRCm39) |
T447I |
probably damaging |
Het |
| Eif4g3 |
T |
C |
4: 137,912,059 (GRCm39) |
L1227S |
probably damaging |
Het |
| Elac1 |
C |
A |
18: 73,880,310 (GRCm39) |
E29* |
probably null |
Het |
| Entrep1 |
T |
A |
19: 23,962,196 (GRCm39) |
Q269L |
probably damaging |
Het |
| Ephb6 |
C |
T |
6: 41,590,293 (GRCm39) |
A15V |
probably benign |
Het |
| Fancc |
G |
T |
13: 63,548,090 (GRCm39) |
L70M |
possibly damaging |
Het |
| Fgd6 |
T |
A |
10: 93,959,425 (GRCm39) |
M1041K |
probably damaging |
Het |
| Fn1 |
A |
G |
1: 71,663,446 (GRCm39) |
V1014A |
possibly damaging |
Het |
| Galnt1 |
C |
T |
18: 24,402,567 (GRCm39) |
T308I |
possibly damaging |
Het |
| Garre1 |
T |
C |
7: 33,956,869 (GRCm39) |
Q332R |
probably damaging |
Het |
| Gpr63 |
T |
A |
4: 25,007,357 (GRCm39) |
V27D |
possibly damaging |
Het |
| Hcfc2 |
T |
C |
10: 82,536,822 (GRCm39) |
V78A |
probably damaging |
Het |
| Hexd |
T |
A |
11: 121,109,136 (GRCm39) |
|
probably benign |
Het |
| Hipk1 |
T |
C |
3: 103,668,960 (GRCm39) |
T479A |
possibly damaging |
Het |
| Hkdc1 |
T |
C |
10: 62,229,544 (GRCm39) |
D711G |
probably damaging |
Het |
| Ifna16 |
A |
T |
4: 88,594,912 (GRCm39) |
F61Y |
probably damaging |
Het |
| Kif5b |
T |
A |
18: 6,209,021 (GRCm39) |
R914W |
probably damaging |
Het |
| Lpo |
T |
C |
11: 87,708,660 (GRCm39) |
T113A |
probably benign |
Het |
| Mmp21 |
T |
C |
7: 133,276,746 (GRCm39) |
D419G |
probably damaging |
Het |
| Naf1 |
A |
G |
8: 67,313,628 (GRCm39) |
T204A |
possibly damaging |
Het |
| Nsmce4a |
T |
C |
7: 130,141,587 (GRCm39) |
T201A |
probably benign |
Het |
| Nup160 |
T |
A |
2: 90,548,208 (GRCm39) |
N980K |
probably damaging |
Het |
| Odad2 |
T |
C |
18: 7,268,464 (GRCm39) |
K352E |
probably benign |
Het |
| Or13c7d |
T |
C |
4: 43,770,346 (GRCm39) |
I222V |
possibly damaging |
Het |
| Or14j2 |
A |
T |
17: 37,885,542 (GRCm39) |
F257L |
probably benign |
Het |
| Or2d3c |
T |
A |
7: 106,526,366 (GRCm39) |
Q100L |
probably damaging |
Het |
| Pcdhb19 |
A |
G |
18: 37,631,476 (GRCm39) |
T424A |
probably benign |
Het |
| Pclo |
C |
T |
5: 14,719,325 (GRCm39) |
A1154V |
unknown |
Het |
| Pramel28 |
C |
A |
4: 143,691,770 (GRCm39) |
A318S |
probably benign |
Het |
| Psma8 |
T |
A |
18: 14,890,404 (GRCm39) |
D181E |
probably benign |
Het |
| Rhpn2 |
C |
A |
7: 35,053,446 (GRCm39) |
|
probably benign |
Het |
| Serpinb6e |
G |
T |
13: 34,022,967 (GRCm39) |
H139N |
possibly damaging |
Het |
| Slc26a7 |
T |
A |
4: 14,533,642 (GRCm39) |
I394F |
probably damaging |
Het |
| Spmip5 |
T |
C |
19: 58,776,153 (GRCm39) |
E100G |
probably damaging |
Het |
| Stxbp5l |
ATTTT |
ATTTTT |
16: 37,036,414 (GRCm39) |
|
probably null |
Het |
| Taok3 |
T |
C |
5: 117,379,227 (GRCm39) |
S421P |
probably benign |
Het |
| Tas2r143 |
T |
G |
6: 42,377,828 (GRCm39) |
D219E |
probably damaging |
Het |
| Tcaf1 |
G |
A |
6: 42,663,707 (GRCm39) |
R58C |
probably damaging |
Het |
| Tenm3 |
A |
T |
8: 48,688,383 (GRCm39) |
Y2401* |
probably null |
Het |
| Tut1 |
T |
C |
19: 8,937,116 (GRCm39) |
V200A |
possibly damaging |
Het |
| Unc5c |
T |
A |
3: 141,509,467 (GRCm39) |
|
probably benign |
Het |
| Vmn2r28 |
T |
G |
7: 5,493,473 (GRCm39) |
I158L |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,404,134 (GRCm39) |
H19L |
probably benign |
Het |
| Xpo4 |
A |
G |
14: 57,828,475 (GRCm39) |
M795T |
probably benign |
Het |
| Zc3h12a |
C |
A |
4: 125,014,743 (GRCm39) |
R247L |
probably damaging |
Het |
| Zfp521 |
C |
A |
18: 13,979,137 (GRCm39) |
L425F |
probably damaging |
Het |
|
| Other mutations in Insrr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00718:Insrr
|
APN |
3 |
87,720,981 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00801:Insrr
|
APN |
3 |
87,721,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Insrr
|
APN |
3 |
87,708,099 (GRCm39) |
nonsense |
probably null |
|
|
IGL01755:Insrr
|
APN |
3 |
87,721,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02100:Insrr
|
APN |
3 |
87,718,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02261:Insrr
|
APN |
3 |
87,708,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Insrr
|
APN |
3 |
87,717,216 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02387:Insrr
|
APN |
3 |
87,720,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02478:Insrr
|
APN |
3 |
87,716,719 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02550:Insrr
|
APN |
3 |
87,711,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02555:Insrr
|
APN |
3 |
87,721,124 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02673:Insrr
|
APN |
3 |
87,720,368 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02724:Insrr
|
APN |
3 |
87,716,879 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02798:Insrr
|
APN |
3 |
87,717,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02969:Insrr
|
APN |
3 |
87,721,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL03073:Insrr
|
APN |
3 |
87,717,245 (GRCm39) |
splice site |
probably benign |
|
|
IGL03178:Insrr
|
APN |
3 |
87,709,848 (GRCm39) |
splice site |
probably null |
|
|
IGL03389:Insrr
|
APN |
3 |
87,716,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Insrr
|
APN |
3 |
87,716,638 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL02799:Insrr
|
UTSW |
3 |
87,720,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Insrr
|
UTSW |
3 |
87,716,923 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0357:Insrr
|
UTSW |
3 |
87,715,953 (GRCm39) |
splice site |
probably null |
|
|
R0501:Insrr
|
UTSW |
3 |
87,717,991 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0504:Insrr
|
UTSW |
3 |
87,720,463 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0522:Insrr
|
UTSW |
3 |
87,708,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Insrr
|
UTSW |
3 |
87,721,744 (GRCm39) |
splice site |
probably benign |
|
|
R0558:Insrr
|
UTSW |
3 |
87,718,288 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0599:Insrr
|
UTSW |
3 |
87,720,440 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1312:Insrr
|
UTSW |
3 |
87,707,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Insrr
|
UTSW |
3 |
87,711,369 (GRCm39) |
missense |
probably benign |
|
|
R1785:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1786:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1892:Insrr
|
UTSW |
3 |
87,721,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Insrr
|
UTSW |
3 |
87,721,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2080:Insrr
|
UTSW |
3 |
87,721,598 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2094:Insrr
|
UTSW |
3 |
87,710,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2130:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2131:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2133:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2220:Insrr
|
UTSW |
3 |
87,716,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2259:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2404:Insrr
|
UTSW |
3 |
87,709,974 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4027:Insrr
|
UTSW |
3 |
87,716,906 (GRCm39) |
missense |
probably benign |
|
|
R4042:Insrr
|
UTSW |
3 |
87,721,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4511:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4571:Insrr
|
UTSW |
3 |
87,708,194 (GRCm39) |
missense |
probably benign |
|
|
R4870:Insrr
|
UTSW |
3 |
87,718,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Insrr
|
UTSW |
3 |
87,722,572 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5393:Insrr
|
UTSW |
3 |
87,718,007 (GRCm39) |
splice site |
probably null |
|
|
R5685:Insrr
|
UTSW |
3 |
87,707,803 (GRCm39) |
splice site |
probably null |
|
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6047:Insrr
|
UTSW |
3 |
87,711,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6276:Insrr
|
UTSW |
3 |
87,707,826 (GRCm39) |
nonsense |
probably null |
|
|
R6298:Insrr
|
UTSW |
3 |
87,720,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6726:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6727:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6728:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6796:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7041:Insrr
|
UTSW |
3 |
87,722,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7169:Insrr
|
UTSW |
3 |
87,715,901 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7270:Insrr
|
UTSW |
3 |
87,710,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Insrr
|
UTSW |
3 |
87,721,623 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7398:Insrr
|
UTSW |
3 |
87,716,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7473:Insrr
|
UTSW |
3 |
87,711,838 (GRCm39) |
splice site |
probably null |
|
|
R7815:Insrr
|
UTSW |
3 |
87,716,002 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8159:Insrr
|
UTSW |
3 |
87,707,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8289:Insrr
|
UTSW |
3 |
87,721,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8309:Insrr
|
UTSW |
3 |
87,717,749 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8312:Insrr
|
UTSW |
3 |
87,707,791 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8445:Insrr
|
UTSW |
3 |
87,720,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8917:Insrr
|
UTSW |
3 |
87,718,276 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8960:Insrr
|
UTSW |
3 |
87,720,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Insrr
|
UTSW |
3 |
87,720,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:Insrr
|
UTSW |
3 |
87,720,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9251:Insrr
|
UTSW |
3 |
87,717,391 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9327:Insrr
|
UTSW |
3 |
87,721,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9646:Insrr
|
UTSW |
3 |
87,721,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF022:Insrr
|
UTSW |
3 |
87,711,792 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1177:Insrr
|
UTSW |
3 |
87,708,134 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
Z1192:Insrr
|
UTSW |
3 |
87,709,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAGCTGATGAGACTCTGCTG -3'
(R):5'- TGTGAGTTCAGATGCCTCCC -3'
Sequencing Primer
(F):5'- TGATGAGACTCTGCTGGCAGC -3'
(R):5'- GAGTTCAGATGCCTCCCTTTCTGG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation