Mutagenetix > Incidental Mutation

Incidental Mutation 'R8991:Fsip2'

684388

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

068716-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.174) question?

Stock #

R8991 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

82943634-83008937 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 82985026 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 3701 (V3701A)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000143764
AA Change: V3701A

PolyPhen 2 Score 0.326 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: V3701A

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921524L21Rik	A	T	18: 6,620,232 (GRCm38)	K54I	probably damaging	Het
Ankrd34b	T	A	13: 92,439,217 (GRCm38)	I319K	probably benign	Het
Art2b	G	A	7: 101,580,383 (GRCm38)	A103V	probably damaging	Het
Atmin	T	G	8: 116,952,926 (GRCm38)	F126C	probably damaging	Het
Cc2d1b	A	T	4: 108,624,946 (GRCm38)	N139I	probably benign	Het
Cep128	T	C	12: 91,234,213 (GRCm38)	Y794C	probably damaging	Het
Cic	T	A	7: 25,289,460 (GRCm38)	V1829D	probably damaging	Het
Cnep1r1	G	A	8: 88,129,819 (GRCm38)	R99Q	unknown	Het
Cpq	G	C	15: 33,213,207 (GRCm38)	R124P	probably damaging	Het
Crtc3	A	T	7: 80,677,443 (GRCm38)	V45D	probably damaging	Het
Dchs2	T	G	3: 83,128,836 (GRCm38)	S297A	probably benign	Het
Dnah9	A	T	11: 65,886,680 (GRCm38)	S3681T	probably damaging	Het
Dock8	T	C	19: 25,188,367 (GRCm38)	Y1872H	possibly damaging	Het
Fbn2	T	A	18: 58,106,323 (GRCm38)	Q558L	probably damaging	Het
Fn1	A	G	1: 71,637,332 (GRCm38)	V580A	probably benign	Het
Fscn3	C	T	6: 28,434,473 (GRCm38)	T349I	probably benign	Het
Hectd4	T	C	5: 121,358,284 (GRCm38)	V3913A	probably benign	Het
Htt	G	A	5: 34,905,718 (GRCm38)	G2898D	probably damaging	Het
Ighv3-4	T	G	12: 114,253,646 (GRCm38)	E108D	probably benign	Het
Irx5	G	T	8: 92,360,507 (GRCm38)	E356*	probably null	Het
Kcnh6	A	G	11: 106,019,145 (GRCm38)	I499V	possibly damaging	Het
Kcnj10	T	A	1: 172,369,396 (GRCm38)	I159N	probably damaging	Het
Kcnmb4	T	A	10: 116,446,333 (GRCm38)	H153L	probably benign	Het
Klhl8	T	C	5: 103,870,538 (GRCm38)	N409S	probably benign	Het
Ksr1	A	G	11: 79,045,188 (GRCm38)	S117P	probably benign	Het
Lrfn3	A	T	7: 30,359,819 (GRCm38)	V327E	probably damaging	Het
Mrc2	C	A	11: 105,338,914 (GRCm38)	H724Q	probably benign	Het
Mtf2	T	A	5: 108,100,939 (GRCm38)	F372L	probably benign	Het
Nipbl	A	T	15: 8,291,513 (GRCm38)	D2703E	probably damaging	Het
Nova1	T	C	12: 46,817,017 (GRCm38)	Y50C	unknown	Het
Ofcc1	T	A	13: 40,142,801 (GRCm38)	Y519F	probably benign	Het
Olfr1180	A	C	2: 88,412,379 (GRCm38)	M93R	probably damaging	Het
Olfr1278	T	C	2: 111,293,003 (GRCm38)	I245T	probably damaging	Het
Olfr1314	A	T	2: 112,092,337 (GRCm38)	D121E	probably damaging	Het
Olfr170	T	A	16: 19,605,761 (GRCm38)	K301N	probably damaging	Het
Pclo	C	T	5: 14,669,311 (GRCm38)	A1154V	unknown	Het
Phrf1	A	G	7: 141,243,758 (GRCm38)	D4G	unknown	Het
Ppp4r3b	A	T	11: 29,173,306 (GRCm38)	M1L	probably damaging	Het
Prmt7	A	G	8: 106,217,242 (GRCm38)		probably null	Het
Retnlg	A	G	16: 48,873,675 (GRCm38)	T65A	possibly damaging	Het
Sbf2	T	C	7: 110,312,689 (GRCm38)	N1763D	probably benign	Het
Scn7a	A	G	2: 66,684,244 (GRCm38)	F1062S	possibly damaging	Het
Scube3	A	C	17: 28,164,053 (GRCm38)	K402Q	probably damaging	Het
Skiv2l	T	A	17: 34,840,190 (GRCm38)	D1067V	probably damaging	Het
Slc25a22	C	A	7: 141,433,958 (GRCm38)	D30Y	probably damaging	Het
Smim17	A	T	7: 6,424,721 (GRCm38)	Q2L	possibly damaging	Het
Son	G	T	16: 91,656,478 (GRCm38)	M704I	probably benign	Het
Son	C	T	16: 91,656,720 (GRCm38)	S785F	possibly damaging	Het
Tnfrsf21	G	A	17: 43,085,408 (GRCm38)	V528M	probably benign	Het
Tnks1bp1	T	C	2: 85,063,946 (GRCm38)	S1406P	probably benign	Het
Trim21	A	T	7: 102,563,701 (GRCm38)	V130E	probably benign	Het
Try5	T	A	6: 41,312,361 (GRCm38)	I94F	probably benign	Het
Tubb4a	C	T	17: 57,081,169 (GRCm38)	V286I	probably benign	Het
Vmn1r180	T	A	7: 23,952,651 (GRCm38)	S80T	probably benign	Het
Vmn2r114	A	C	17: 23,310,312 (GRCm38)	I272S	probably damaging	Het
Vmn2r12	A	T	5: 109,086,167 (GRCm38)	Y726*	probably null	Het
Zdhhc16	T	C	19: 41,938,026 (GRCm38)	F83L	probably damaging	Het
Zfp521	C	A	18: 13,846,080 (GRCm38)	L425F	probably damaging	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,990,386 (GRCm38)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,991,313 (GRCm38)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,999,819 (GRCm38)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,992,982 (GRCm38)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,977,519 (GRCm38)	missense	probably benign
IGL01554:Fsip2	APN	2	82,977,278 (GRCm38)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,991,086 (GRCm38)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,978,347 (GRCm38)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,982,639 (GRCm38)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,984,929 (GRCm38)	missense	probably benign
IGL01918:Fsip2	APN	2	82,992,138 (GRCm38)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,994,005 (GRCm38)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,993,867 (GRCm38)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,991,860 (GRCm38)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,978,721 (GRCm38)	missense	probably benign
IGL02155:Fsip2	APN	2	82,998,352 (GRCm38)	missense	probably benign
IGL02219:Fsip2	APN	2	82,977,830 (GRCm38)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,982,772 (GRCm38)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,978,793 (GRCm38)	missense	probably benign
IGL02478:Fsip2	APN	2	82,984,392 (GRCm38)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,978,855 (GRCm38)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,992,003 (GRCm38)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,949,492 (GRCm38)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,993,063 (GRCm38)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,998,318 (GRCm38)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,982,157 (GRCm38)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,951,026 (GRCm38)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,993,495 (GRCm38)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,992,357 (GRCm38)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,983,054 (GRCm38)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,990,624 (GRCm38)	intron	probably benign
IGL03076:Fsip2	APN	2	82,982,138 (GRCm38)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,978,076 (GRCm38)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,977,393 (GRCm38)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,990,470 (GRCm38)	missense	probably benign
bubblegum	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
Dao	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
engulf	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
envelope	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
gladius	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
glove	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
Katana	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
scarf	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
Sock	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
swaddle	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
wrap	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
Wrapper	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,988,412 (GRCm38)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,984,365 (GRCm38)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,984,362 (GRCm38)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,990,852 (GRCm38)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,999,857 (GRCm38)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,976,608 (GRCm38)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,984,925 (GRCm38)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,991,121 (GRCm38)	missense	probably benign
R0149:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,980,807 (GRCm38)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,985,177 (GRCm38)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,985,896 (GRCm38)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,983,333 (GRCm38)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,984,564 (GRCm38)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,991,075 (GRCm38)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,977,785 (GRCm38)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,946,952 (GRCm38)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,993,795 (GRCm38)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,977,533 (GRCm38)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,944,140 (GRCm38)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,988,958 (GRCm38)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,976,897 (GRCm38)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,986,169 (GRCm38)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,991,359 (GRCm38)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,982,339 (GRCm38)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,986,273 (GRCm38)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,985,484 (GRCm38)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,998,031 (GRCm38)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,989,436 (GRCm38)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,988,461 (GRCm38)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,975,034 (GRCm38)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,991,500 (GRCm38)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,975,226 (GRCm38)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,975,017 (GRCm38)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,981,011 (GRCm38)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,989,763 (GRCm38)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,989,408 (GRCm38)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,989,745 (GRCm38)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,998,063 (GRCm38)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,987,195 (GRCm38)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,979,811 (GRCm38)	missense	probably benign
R1520:Fsip2	UTSW	2	82,980,714 (GRCm38)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,981,587 (GRCm38)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,986,282 (GRCm38)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,978,517 (GRCm38)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,986,345 (GRCm38)	missense	probably benign
R1700:Fsip2	UTSW	2	82,991,737 (GRCm38)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,974,945 (GRCm38)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,989,912 (GRCm38)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,987,711 (GRCm38)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,984,896 (GRCm38)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,999,841 (GRCm38)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,977,562 (GRCm38)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,984,589 (GRCm38)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,993,257 (GRCm38)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,980,783 (GRCm38)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,986,733 (GRCm38)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,980,558 (GRCm38)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,991,550 (GRCm38)	missense	probably benign
R1965:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,979,831 (GRCm38)	missense	probably benign
R1988:Fsip2	UTSW	2	82,976,517 (GRCm38)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,989,444 (GRCm38)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,978,512 (GRCm38)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,976,355 (GRCm38)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	83,008,815 (GRCm38)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,988,579 (GRCm38)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,990,271 (GRCm38)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,977,479 (GRCm38)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,962,751 (GRCm38)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,975,093 (GRCm38)	missense	probably benign
R2344:Fsip2	UTSW	2	82,989,913 (GRCm38)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,976,249 (GRCm38)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,980,720 (GRCm38)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,985,341 (GRCm38)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,979,610 (GRCm38)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,951,657 (GRCm38)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,978,167 (GRCm38)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,990,431 (GRCm38)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,979,045 (GRCm38)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,991,524 (GRCm38)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,986,510 (GRCm38)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,992,010 (GRCm38)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,986,727 (GRCm38)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,984,909 (GRCm38)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,988,967 (GRCm38)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,978,217 (GRCm38)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,982,714 (GRCm38)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,950,946 (GRCm38)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,989,606 (GRCm38)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,986,415 (GRCm38)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,958,662 (GRCm38)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,983,518 (GRCm38)	missense	probably benign
R4042:Fsip2	UTSW	2	82,983,552 (GRCm38)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,982,901 (GRCm38)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,987,069 (GRCm38)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,977,857 (GRCm38)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,991,206 (GRCm38)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,951,665 (GRCm38)	missense	probably benign
R4549:Fsip2	UTSW	2	82,989,628 (GRCm38)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,984,953 (GRCm38)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,986,166 (GRCm38)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,978,673 (GRCm38)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,987,759 (GRCm38)	missense	probably benign
R4700:Fsip2	UTSW	2	82,987,029 (GRCm38)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,974,859 (GRCm38)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,975,353 (GRCm38)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,989,285 (GRCm38)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,982,108 (GRCm38)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,987,700 (GRCm38)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,988,442 (GRCm38)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,990,171 (GRCm38)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,985,471 (GRCm38)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,949,395 (GRCm38)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,990,951 (GRCm38)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,974,858 (GRCm38)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,988,094 (GRCm38)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,981,493 (GRCm38)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,993,770 (GRCm38)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,985,040 (GRCm38)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,977,414 (GRCm38)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,946,932 (GRCm38)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,985,878 (GRCm38)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,979,429 (GRCm38)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,989,133 (GRCm38)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,988,492 (GRCm38)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,991,116 (GRCm38)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,991,985 (GRCm38)	missense	probably benign
R5119:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,981,424 (GRCm38)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,978,572 (GRCm38)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,982,994 (GRCm38)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,993,161 (GRCm38)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,978,581 (GRCm38)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,988,145 (GRCm38)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,989,841 (GRCm38)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,975,398 (GRCm38)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,990,918 (GRCm38)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,982,228 (GRCm38)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,979,886 (GRCm38)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,985,310 (GRCm38)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,985,198 (GRCm38)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,950,912 (GRCm38)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,950,908 (GRCm38)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,962,746 (GRCm38)	missense	probably benign
R5568:Fsip2	UTSW	2	82,986,564 (GRCm38)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,998,128 (GRCm38)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,988,095 (GRCm38)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,987,494 (GRCm38)	nonsense	probably null
R5712:Fsip2	UTSW	2	83,008,848 (GRCm38)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,977,916 (GRCm38)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,984,740 (GRCm38)	missense	probably benign
R5881:Fsip2	UTSW	2	82,984,441 (GRCm38)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,992,609 (GRCm38)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,988,508 (GRCm38)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,986,748 (GRCm38)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,977,491 (GRCm38)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,963,313 (GRCm38)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,990,468 (GRCm38)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,987,939 (GRCm38)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,992,127 (GRCm38)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,985,673 (GRCm38)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,979,433 (GRCm38)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,991,044 (GRCm38)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,993,768 (GRCm38)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,987,945 (GRCm38)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,987,257 (GRCm38)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,980,727 (GRCm38)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,982,454 (GRCm38)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,989,883 (GRCm38)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,980,441 (GRCm38)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,988,898 (GRCm38)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,993,072 (GRCm38)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,992,684 (GRCm38)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,983,492 (GRCm38)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,982,313 (GRCm38)	missense	probably benign
R6621:Fsip2	UTSW	2	82,989,814 (GRCm38)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,983,227 (GRCm38)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,967,817 (GRCm38)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,979,534 (GRCm38)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,986,432 (GRCm38)	missense	probably benign
R6790:Fsip2	UTSW	2	82,990,939 (GRCm38)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,980,959 (GRCm38)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,985,200 (GRCm38)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,983,625 (GRCm38)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,985,988 (GRCm38)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,978,717 (GRCm38)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,948,286 (GRCm38)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,976,954 (GRCm38)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,986,925 (GRCm38)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,990,635 (GRCm38)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,990,891 (GRCm38)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,980,734 (GRCm38)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,983,152 (GRCm38)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,987,624 (GRCm38)	missense	probably benign
R7126:Fsip2	UTSW	2	82,983,141 (GRCm38)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,982,741 (GRCm38)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,981,197 (GRCm38)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,986,227 (GRCm38)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,993,237 (GRCm38)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,989,068 (GRCm38)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,983,671 (GRCm38)	missense	probably benign
R7228:Fsip2	UTSW	2	82,992,307 (GRCm38)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,982,140 (GRCm38)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,993,263 (GRCm38)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,979,081 (GRCm38)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,982,130 (GRCm38)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,980,519 (GRCm38)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,989,691 (GRCm38)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,983,118 (GRCm38)	missense	probably benign
R7343:Fsip2	UTSW	2	82,979,367 (GRCm38)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,988,796 (GRCm38)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,990,319 (GRCm38)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,985,257 (GRCm38)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,980,097 (GRCm38)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,951,680 (GRCm38)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,988,550 (GRCm38)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,984,852 (GRCm38)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,993,993 (GRCm38)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,989,017 (GRCm38)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,975,241 (GRCm38)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,986,912 (GRCm38)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,981,805 (GRCm38)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,990,111 (GRCm38)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,980,908 (GRCm38)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,988,379 (GRCm38)	missense	probably benign
R7811:Fsip2	UTSW	2	82,998,453 (GRCm38)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,976,700 (GRCm38)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,977,824 (GRCm38)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,951,021 (GRCm38)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,985,776 (GRCm38)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,988,449 (GRCm38)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
R8034:Fsip2	UTSW	2	82,989,355 (GRCm38)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,985,978 (GRCm38)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,958,673 (GRCm38)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,992,952 (GRCm38)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,975,797 (GRCm38)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,987,677 (GRCm38)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,984,744 (GRCm38)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,976,607 (GRCm38)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,990,464 (GRCm38)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,978,143 (GRCm38)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,981,002 (GRCm38)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,988,380 (GRCm38)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,990,755 (GRCm38)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,987,854 (GRCm38)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,991,895 (GRCm38)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8419:Fsip2	UTSW	2	82,978,619 (GRCm38)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,981,566 (GRCm38)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,977,086 (GRCm38)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8459:Fsip2	UTSW	2	82,979,678 (GRCm38)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,979,940 (GRCm38)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,946,992 (GRCm38)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,991,527 (GRCm38)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,984,902 (GRCm38)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,981,109 (GRCm38)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,985,478 (GRCm38)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,983,109 (GRCm38)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,991,262 (GRCm38)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,990,438 (GRCm38)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,979,180 (GRCm38)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,977,337 (GRCm38)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,986,640 (GRCm38)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,980,594 (GRCm38)	missense	probably benign
R8926:Fsip2	UTSW	2	82,993,583 (GRCm38)	missense	possibly damaging	0.84
R9014:Fsip2	UTSW	2	82,976,554 (GRCm38)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,986,731 (GRCm38)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,998,201 (GRCm38)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,975,836 (GRCm38)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,976,957 (GRCm38)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,985,759 (GRCm38)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,982,826 (GRCm38)	missense	probably benign
R9149:Fsip2	UTSW	2	82,982,030 (GRCm38)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,985,230 (GRCm38)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,987,500 (GRCm38)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,990,081 (GRCm38)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,992,718 (GRCm38)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,985,614 (GRCm38)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,977,318 (GRCm38)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,988,260 (GRCm38)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,988,403 (GRCm38)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,980,695 (GRCm38)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,992,412 (GRCm38)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,989,449 (GRCm38)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,975,563 (GRCm38)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,986,358 (GRCm38)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,975,788 (GRCm38)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,986,941 (GRCm38)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,962,718 (GRCm38)	missense	probably benign
R9523:Fsip2	UTSW	2	82,977,628 (GRCm38)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,967,829 (GRCm38)	missense	probably benign
R9636:Fsip2	UTSW	2	82,990,219 (GRCm38)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,991,640 (GRCm38)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,988,928 (GRCm38)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,975,882 (GRCm38)	missense	probably benign
R9705:Fsip2	UTSW	2	82,993,290 (GRCm38)	missense	probably benign
R9739:Fsip2	UTSW	2	82,993,552 (GRCm38)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,987,897 (GRCm38)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,991,650 (GRCm38)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,979,881 (GRCm38)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,991,521 (GRCm38)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,992,532 (GRCm38)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,977,840 (GRCm38)	missense	probably benign
RF028:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,982,507 (GRCm38)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,951,020 (GRCm38)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,954,946 (GRCm38)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,976,778 (GRCm38)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,987,463 (GRCm38)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,988,634 (GRCm38)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,987,653 (GRCm38)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,975,448 (GRCm38)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,989,665 (GRCm38)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,984,524 (GRCm38)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,946,960 (GRCm38)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,987,203 (GRCm38)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- TCTGTCCAGGAGTGACTTCTTC -3'
(R):5'- CCTACATTGTTTGCAAGGCTTC -3'

Sequencing Primer
(F):5'- CCAGGAGTGACTTCTTCTGATTTTG -3'
(R):5'- CATTGTTTGCAAGGCTTCTATTAC -3'

Posted On

2021-10-11