Incidental Mutation 'R8995:Shprh'
| ID |
684680 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| MMRRC Submission |
068826-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8995 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
11025171-11093339 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 11040574 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 682
(Y682*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039422
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000159541]
[ENSMUST00000159810]
[ENSMUST00000160461]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000044053
AA Change: Y682*
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
AA Change: Y682*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000054814
AA Change: Y682*
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
AA Change: Y682*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159541
AA Change: Y682*
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
AA Change: Y682*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159810
AA Change: Y682*
|
| SMART Domains |
Protein: ENSMUSP00000125457
Gene: ENSMUSG00000090112
AA Change: Y682*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
2e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
Blast:DEXDc
|
948 |
1026 |
2e-9 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000160461
AA Change: Y162*
|
| SMART Domains |
Protein: ENSMUSP00000125127
Gene: ENSMUSG00000090112
AA Change: Y162*
| Domain | Start | End | E-Value | Type |
|---|
|
PHD
|
131 |
178 |
2.33e-5 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 98.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700018B08Rik |
A |
G |
8: 122,257,764 (GRCm39) |
*214R |
probably null |
Het |
| Acd |
A |
G |
8: 106,427,131 (GRCm39) |
L93P |
probably damaging |
Het |
| Adgrv1 |
GTT |
GT |
13: 81,553,457 (GRCm39) |
|
probably null |
Het |
| Aldh1b1 |
T |
A |
4: 45,803,413 (GRCm39) |
M317K |
possibly damaging |
Het |
| Arfgap2 |
C |
A |
2: 91,103,929 (GRCm39) |
Q342K |
probably damaging |
Het |
| Arhgef16 |
C |
T |
4: 154,371,495 (GRCm39) |
E233K |
probably damaging |
Het |
| Asxl1 |
C |
T |
2: 153,235,886 (GRCm39) |
R323C |
probably damaging |
Het |
| Bank1 |
G |
T |
3: 135,772,264 (GRCm39) |
D656E |
possibly damaging |
Het |
| Bdh2 |
A |
G |
3: 135,000,989 (GRCm39) |
M120V |
probably damaging |
Het |
| Bend7 |
A |
G |
2: 4,749,103 (GRCm39) |
I73M |
probably damaging |
Het |
| Cd207 |
C |
A |
6: 83,652,891 (GRCm39) |
D80Y |
probably damaging |
Het |
| Cdon |
A |
G |
9: 35,398,093 (GRCm39) |
T937A |
probably damaging |
Het |
| Cntn1 |
G |
A |
15: 92,132,347 (GRCm39) |
V148M |
probably damaging |
Het |
| Csnk2a1-ps3 |
T |
A |
1: 156,352,873 (GRCm39) |
V358E |
probably benign |
Het |
| Ddx50 |
A |
G |
10: 62,469,862 (GRCm39) |
I375T |
probably damaging |
Het |
| Dhrs1 |
T |
A |
14: 55,977,396 (GRCm39) |
T241S |
probably benign |
Het |
| Eef1b2 |
T |
C |
1: 63,217,629 (GRCm39) |
Y79H |
probably damaging |
Het |
| Elmod2 |
A |
G |
8: 84,049,315 (GRCm39) |
C84R |
probably benign |
Het |
| Exo1 |
A |
G |
1: 175,736,127 (GRCm39) |
H837R |
probably benign |
Het |
| Fat3 |
T |
C |
9: 16,286,898 (GRCm39) |
N875S |
probably damaging |
Het |
| Flvcr1 |
A |
T |
1: 190,743,817 (GRCm39) |
L413Q |
probably damaging |
Het |
| Fras1 |
G |
T |
5: 96,860,415 (GRCm39) |
V2154F |
possibly damaging |
Het |
| Golm2 |
A |
C |
2: 121,756,199 (GRCm39) |
E409D |
probably damaging |
Het |
| Hectd4 |
G |
A |
5: 121,392,422 (GRCm39) |
V229M |
possibly damaging |
Het |
| Ifitm6 |
A |
T |
7: 140,596,617 (GRCm39) |
V52E |
probably damaging |
Het |
| Igkv4-58 |
A |
G |
6: 69,477,511 (GRCm39) |
S29P |
probably damaging |
Het |
| Klc1 |
G |
A |
12: 111,743,344 (GRCm39) |
A224T |
probably damaging |
Het |
| Knl1 |
T |
C |
2: 118,902,990 (GRCm39) |
S1564P |
probably benign |
Het |
| Krt25 |
T |
C |
11: 99,207,382 (GRCm39) |
D399G |
probably benign |
Het |
| Lamc1 |
T |
C |
1: 153,207,993 (GRCm39) |
Q98R |
probably benign |
Het |
| Lpar1 |
T |
A |
4: 58,486,954 (GRCm39) |
M106L |
probably damaging |
Het |
| Mpc1 |
A |
G |
17: 8,502,784 (GRCm39) |
Y21C |
probably benign |
Het |
| Msr1 |
T |
A |
8: 40,042,460 (GRCm39) |
I372F |
possibly damaging |
Het |
| Ndc80 |
T |
C |
17: 71,815,598 (GRCm39) |
N396D |
probably benign |
Het |
| Nphp4 |
G |
A |
4: 152,623,345 (GRCm39) |
R673H |
probably damaging |
Het |
| Nsd3 |
T |
C |
8: 26,131,169 (GRCm39) |
F178S |
probably damaging |
Het |
| Or1p1b |
A |
T |
11: 74,130,620 (GRCm39) |
T77S |
probably benign |
Het |
| Or8g54 |
T |
C |
9: 39,707,313 (GRCm39) |
I214T |
possibly damaging |
Het |
| Pcdhgb7 |
T |
A |
18: 37,885,230 (GRCm39) |
F133L |
probably damaging |
Het |
| Pikfyve |
A |
G |
1: 65,244,746 (GRCm39) |
|
probably null |
Het |
| Pld5 |
A |
T |
1: 175,791,580 (GRCm39) |
D475E |
probably benign |
Het |
| Potefam3f |
A |
T |
8: 20,479,025 (GRCm39) |
H11L |
|
Het |
| Prop1 |
G |
A |
11: 50,841,887 (GRCm39) |
P173L |
possibly damaging |
Het |
| Rabepk |
G |
A |
2: 34,689,842 (GRCm39) |
|
probably benign |
Het |
| Reln |
A |
G |
5: 22,184,577 (GRCm39) |
I1646T |
probably benign |
Het |
| Rexo1 |
A |
T |
10: 80,386,095 (GRCm39) |
L321Q |
probably damaging |
Het |
| Rfx3 |
T |
A |
19: 27,783,725 (GRCm39) |
E382V |
probably benign |
Het |
| Rnf20 |
C |
T |
4: 49,648,437 (GRCm39) |
T415I |
possibly damaging |
Het |
| Rpl10-ps3 |
T |
A |
9: 50,256,078 (GRCm39) |
D55V |
probably benign |
Het |
| Sag |
A |
G |
1: 87,733,052 (GRCm39) |
T7A |
probably benign |
Het |
| Saysd1 |
G |
A |
14: 20,133,005 (GRCm39) |
R51C |
probably damaging |
Het |
| Slc6a13 |
T |
C |
6: 121,302,012 (GRCm39) |
I198T |
probably damaging |
Het |
| Slx9 |
G |
A |
10: 77,333,303 (GRCm39) |
R121* |
probably null |
Het |
| Smyd5 |
C |
A |
6: 85,415,829 (GRCm39) |
C101* |
probably null |
Het |
| Spata31d1d |
A |
G |
13: 59,874,421 (GRCm39) |
V1038A |
probably benign |
Het |
| Stat6 |
T |
C |
10: 127,494,511 (GRCm39) |
S692P |
probably benign |
Het |
| Tbc1d9 |
A |
T |
8: 83,998,180 (GRCm39) |
M1246L |
probably benign |
Het |
| Tmprss5 |
T |
A |
9: 49,025,894 (GRCm39) |
|
probably null |
Het |
| Trim12a |
A |
T |
7: 103,953,532 (GRCm39) |
M193K |
probably benign |
Het |
| Ube2t |
T |
A |
1: 134,899,658 (GRCm39) |
L102H |
probably damaging |
Het |
| Ubr1 |
G |
A |
2: 120,697,034 (GRCm39) |
R1623W |
probably damaging |
Het |
| Ush2a |
T |
G |
1: 188,176,850 (GRCm39) |
M1338R |
probably damaging |
Het |
| Usp36 |
A |
T |
11: 118,175,825 (GRCm39) |
L112Q |
probably damaging |
Het |
| Vmn1r53 |
A |
G |
6: 90,200,757 (GRCm39) |
M189T |
probably benign |
Het |
| Vmn1r54 |
T |
C |
6: 90,246,668 (GRCm39) |
V194A |
probably benign |
Het |
| Vmn2r33 |
A |
G |
7: 7,554,192 (GRCm39) |
V787A |
probably damaging |
Het |
| Vps26a |
A |
G |
10: 62,300,458 (GRCm39) |
I236T |
probably damaging |
Het |
| Vwde |
A |
T |
6: 13,195,996 (GRCm39) |
L343Q |
probably damaging |
Het |
| Xdh |
A |
G |
17: 74,205,369 (GRCm39) |
V1032A |
probably damaging |
Het |
| Zan |
A |
G |
5: 137,393,882 (GRCm39) |
F4523S |
unknown |
Het |
| Zfand5 |
T |
A |
19: 21,254,387 (GRCm39) |
V66E |
probably benign |
Het |
| Zfp658 |
T |
A |
7: 43,222,798 (GRCm39) |
C358S |
possibly damaging |
Het |
| Zfp977 |
T |
A |
7: 42,232,072 (GRCm39) |
R64W |
probably damaging |
Het |
| Zfp995 |
C |
T |
17: 22,099,172 (GRCm39) |
S354N |
probably benign |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,063,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,063,764 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,038,781 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01295:Shprh
|
APN |
10 |
11,059,612 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01387:Shprh
|
APN |
10 |
11,045,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,045,763 (GRCm39) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,066,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,057,246 (GRCm39) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,070,101 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,030,509 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,068,238 (GRCm39) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,062,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,045,853 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0331:Shprh
|
UTSW |
10 |
11,069,914 (GRCm39) |
splice site |
probably benign |
|
|
R0494:Shprh
|
UTSW |
10 |
11,032,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,038,556 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,059,631 (GRCm39) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,038,821 (GRCm39) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,082,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,062,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,035,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,040,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,032,822 (GRCm39) |
missense |
probably benign |
|
|
R1830:Shprh
|
UTSW |
10 |
11,062,655 (GRCm39) |
splice site |
probably null |
|
|
R1898:Shprh
|
UTSW |
10 |
11,062,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,059,541 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,027,864 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,037,979 (GRCm39) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,047,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,042,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,040,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,046,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,045,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,054,501 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,083,604 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,062,262 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,036,215 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,046,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,057,284 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,040,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,032,863 (GRCm39) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,030,449 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,042,301 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,046,041 (GRCm39) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,088,074 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,063,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,054,485 (GRCm39) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,043,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,047,681 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,062,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,070,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,042,289 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,057,252 (GRCm39) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,042,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,042,474 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,040,449 (GRCm39) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,037,924 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
|
|
R7998:Shprh
|
UTSW |
10 |
11,061,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Shprh
|
UTSW |
10 |
11,088,077 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,027,555 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8116:Shprh
|
UTSW |
10 |
11,089,205 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8390:Shprh
|
UTSW |
10 |
11,063,727 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,057,313 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,027,678 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,032,908 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,061,181 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9053:Shprh
|
UTSW |
10 |
11,030,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,038,589 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,036,320 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,038,633 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,081,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,042,235 (GRCm39) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,082,076 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,038,574 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,089,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,040,204 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,040,585 (GRCm39) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,062,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,062,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,040,297 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,027,506 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAAAGACTGTGCTGAGTCGC -3'
(R):5'- AAGCACCACTGTACAGGTTC -3'
Sequencing Primer
(F):5'- ACTGTGCTGAGTCGCCAAAC -3'
(R):5'- TAGCTGCAGTGCCTTACCAG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation