Incidental Mutation 'R9005:Dsc2'
| ID |
685258 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2b, Dsc2a |
| MMRRC Submission |
068835-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9005 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20030633-20059554 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 20038094 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 616
(D616G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042905
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039247
AA Change: D616G
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: D616G
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075214
AA Change: D616G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: D616G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
AA Change: D15G
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
99% (80/81) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110059E24Rik |
C |
T |
19: 21,652,711 (GRCm38) |
|
probably benign |
Het |
| Abcd4 |
C |
T |
12: 84,608,582 (GRCm38) |
W369* |
probably null |
Het |
| Abcf3 |
A |
G |
16: 20,549,306 (GRCm38) |
E98G |
probably benign |
Het |
| Acaca |
A |
T |
11: 84,371,584 (GRCm38) |
D2004V |
probably damaging |
Het |
| Acot5 |
G |
C |
12: 84,069,856 (GRCm38) |
M130I |
|
Het |
| Adamts3 |
C |
T |
5: 89,677,834 (GRCm38) |
E1049K |
probably benign |
Het |
| Agfg2 |
A |
T |
5: 137,652,482 (GRCm38) |
L456Q |
probably damaging |
Het |
| Agtr1b |
T |
A |
3: 20,316,179 (GRCm38) |
T88S |
possibly damaging |
Het |
| Amer2 |
G |
C |
14: 60,379,927 (GRCm38) |
D524H |
probably damaging |
Het |
| Ankrd61 |
T |
A |
5: 143,894,858 (GRCm38) |
T43S |
probably benign |
Het |
| Apcs |
A |
G |
1: 172,894,209 (GRCm38) |
L190P |
probably benign |
Het |
| Arsg |
A |
G |
11: 109,490,520 (GRCm38) |
K30E |
probably benign |
Het |
| Banp |
A |
T |
8: 121,978,702 (GRCm38) |
M104L |
possibly damaging |
Het |
| BC048403 |
A |
G |
10: 121,750,596 (GRCm38) |
Y272C |
probably damaging |
Het |
| BC080695 |
G |
A |
4: 143,571,855 (GRCm38) |
D123N |
probably benign |
Het |
| Caskin1 |
A |
G |
17: 24,499,137 (GRCm38) |
Q268R |
probably benign |
Het |
| Ccdc112 |
A |
G |
18: 46,296,388 (GRCm38) |
V81A |
probably damaging |
Het |
| Cfap44 |
T |
C |
16: 44,460,154 (GRCm38) |
I1432T |
probably damaging |
Het |
| Chd2 |
A |
T |
7: 73,484,546 (GRCm38) |
N684K |
probably damaging |
Het |
| Creb1 |
T |
C |
1: 64,566,319 (GRCm38) |
|
probably null |
Het |
| Ctsc |
C |
T |
7: 88,278,294 (GRCm38) |
T31I |
probably damaging |
Het |
| Cttnbp2 |
C |
A |
6: 18,434,431 (GRCm38) |
R476L |
probably damaging |
Het |
| Cwf19l1 |
T |
C |
19: 44,123,214 (GRCm38) |
D260G |
possibly damaging |
Het |
| Cyp24a1 |
A |
T |
2: 170,494,085 (GRCm38) |
S211T |
probably damaging |
Het |
| Ddx3y |
T |
C |
Y: 1,282,919 (GRCm38) |
N46D |
probably damaging |
Het |
| Dgkz |
G |
T |
2: 91,938,745 (GRCm38) |
H653Q |
probably benign |
Het |
| Dnajc16 |
A |
T |
4: 141,764,634 (GRCm38) |
I626N |
possibly damaging |
Het |
| Dscam |
A |
T |
16: 96,801,380 (GRCm38) |
S621T |
probably damaging |
Het |
| Dst |
T |
A |
1: 34,228,693 (GRCm38) |
V3058E |
probably damaging |
Het |
| Ep400 |
A |
T |
5: 110,711,093 (GRCm38) |
C1125S |
unknown |
Het |
| Glyatl3 |
G |
A |
17: 40,912,728 (GRCm38) |
Q41* |
probably null |
Het |
| Gm7694 |
T |
G |
1: 170,301,358 (GRCm38) |
I201L |
probably damaging |
Het |
| Gnal |
C |
T |
18: 67,088,759 (GRCm38) |
R78* |
probably null |
Het |
| Gtf3c1 |
T |
C |
7: 125,703,897 (GRCm38) |
D122G |
probably benign |
Het |
| Htt |
G |
T |
5: 34,817,751 (GRCm38) |
D622Y |
possibly damaging |
Het |
| Igkv4-92 |
A |
G |
6: 68,755,097 (GRCm38) |
C98R |
probably benign |
Het |
| Incenp |
G |
A |
19: 9,877,724 (GRCm38) |
R608* |
probably null |
Het |
| Kif3c |
G |
A |
12: 3,401,706 (GRCm38) |
R679H |
probably damaging |
Het |
| Kng1 |
T |
A |
16: 23,079,396 (GRCm38) |
H515Q |
probably damaging |
Het |
| Lamb2 |
T |
C |
9: 108,484,171 (GRCm38) |
|
probably null |
Het |
| Malrd1 |
A |
T |
2: 15,845,329 (GRCm38) |
N1253I |
unknown |
Het |
| Map3k21 |
A |
T |
8: 125,910,732 (GRCm38) |
D19V |
|
Het |
| March2 |
G |
T |
17: 33,696,233 (GRCm38) |
P129Q |
probably damaging |
Het |
| Mier2 |
G |
A |
10: 79,548,440 (GRCm38) |
R166W |
probably damaging |
Het |
| Ms4a4d |
T |
A |
19: 11,556,200 (GRCm38) |
D148E |
possibly damaging |
Het |
| Myl4 |
A |
G |
11: 104,577,558 (GRCm38) |
D36G |
probably damaging |
Het |
| Olfr1375 |
G |
A |
11: 51,048,111 (GRCm38) |
M1I |
probably null |
Het |
| Olfr206 |
A |
T |
16: 59,345,566 (GRCm38) |
I45N |
probably damaging |
Het |
| Olfr235 |
A |
G |
19: 12,268,340 (GRCm38) |
T37A |
probably benign |
Het |
| Olfr447 |
T |
C |
6: 42,912,236 (GRCm38) |
S238P |
probably damaging |
Het |
| Pard3 |
G |
A |
8: 127,277,166 (GRCm38) |
S123N |
probably damaging |
Het |
| Parp8 |
T |
C |
13: 116,876,590 (GRCm38) |
N638D |
probably benign |
Het |
| Pgpep1l |
A |
T |
7: 68,237,658 (GRCm38) |
S65T |
probably damaging |
Het |
| Ppp1r13b |
A |
G |
12: 111,830,274 (GRCm38) |
V1068A |
probably benign |
Het |
| Prkd1 |
G |
A |
12: 50,383,402 (GRCm38) |
Q641* |
probably null |
Het |
| Ptgr2 |
T |
C |
12: 84,298,099 (GRCm38) |
V82A |
possibly damaging |
Het |
| Rbm34 |
G |
A |
8: 126,959,582 (GRCm38) |
P225S |
possibly damaging |
Het |
| Rnps1 |
A |
T |
17: 24,418,522 (GRCm38) |
K46I |
unknown |
Het |
| Shank1 |
T |
C |
7: 44,352,985 (GRCm38) |
V1376A |
probably benign |
Het |
| Ski |
A |
T |
4: 155,221,860 (GRCm38) |
Y221N |
probably damaging |
Het |
| Skint6 |
C |
A |
4: 113,238,150 (GRCm38) |
G104V |
probably damaging |
Het |
| Slit2 |
G |
A |
5: 48,302,518 (GRCm38) |
C1380Y |
possibly damaging |
Het |
| Smpd3 |
C |
T |
8: 106,257,426 (GRCm38) |
G554S |
probably benign |
Het |
| Sorbs2 |
T |
G |
8: 45,795,737 (GRCm38) |
V675G |
probably benign |
Het |
| Spdl1 |
C |
A |
11: 34,809,708 (GRCm38) |
C605F |
possibly damaging |
Het |
| Syne1 |
C |
A |
10: 5,205,406 (GRCm38) |
D5568Y |
probably benign |
Het |
| Tac1 |
C |
A |
6: 7,559,141 (GRCm38) |
A111D |
possibly damaging |
Het |
| Tmco1 |
C |
T |
1: 167,308,563 (GRCm38) |
|
probably benign |
Het |
| Tnfrsf1a |
T |
C |
6: 125,356,915 (GRCm38) |
C44R |
probably damaging |
Het |
| Traf3ip3 |
T |
C |
1: 193,181,977 (GRCm38) |
Q366R |
probably benign |
Het |
| Trip10 |
A |
G |
17: 57,262,416 (GRCm38) |
D479G |
probably damaging |
Het |
| Trip11 |
T |
C |
12: 101,878,872 (GRCm38) |
T1536A |
probably benign |
Het |
| Tstd3 |
G |
T |
4: 21,767,082 (GRCm38) |
A13E |
possibly damaging |
Het |
| Urb1 |
T |
C |
16: 90,753,790 (GRCm38) |
K2058R |
probably benign |
Het |
| Usp15 |
A |
T |
10: 123,146,798 (GRCm38) |
I304N |
possibly damaging |
Het |
| Usp18 |
T |
G |
6: 121,252,570 (GRCm38) |
H49Q |
probably benign |
Het |
| Vmn1r56 |
T |
A |
7: 5,196,390 (GRCm38) |
D76V |
probably damaging |
Het |
| Wnk1 |
A |
G |
6: 119,962,432 (GRCm38) |
S167P |
probably damaging |
Het |
| Zfp229 |
G |
A |
17: 21,746,750 (GRCm38) |
A654T |
possibly damaging |
Het |
| Zfp977 |
C |
T |
7: 42,580,658 (GRCm38) |
V148I |
probably benign |
Het |
| Znfx1 |
A |
T |
2: 167,038,736 (GRCm38) |
I1240N |
|
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,041,797 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,035,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,034,683 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,043,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,048,286 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,047,157 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,038,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,046,342 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,043,733 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,045,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,041,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,047,079 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,046,243 (GRCm38) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,046,277 (GRCm38) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,033,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,051,226 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,041,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,041,452 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,050,059 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,033,295 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,032,212 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,045,565 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,034,701 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,050,151 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,046,246 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,032,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,045,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,035,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,045,469 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,045,501 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,032,351 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,050,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,050,142 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,034,583 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,035,303 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,046,279 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,035,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,032,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,047,108 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,045,430 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,035,463 (GRCm38) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,051,175 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,046,238 (GRCm38) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,032,278 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,050,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,035,275 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,051,179 (GRCm38) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,035,335 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,041,926 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,035,394 (GRCm38) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,050,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,041,778 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,316 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,315 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,050,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,046,285 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,034,663 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,034,665 (GRCm38) |
nonsense |
probably null |
|
|
R9017:Dsc2
|
UTSW |
18 |
20,043,911 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,034,707 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,041,716 (GRCm38) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,047,219 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,038,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,046,304 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,035,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGCTCACTGACCATTATACC -3'
(R):5'- ACTGGAACTCTGGGAATCATAC -3'
Sequencing Primer
(F):5'- cacacacacagagagaga -3'
(R):5'- CTCTGGGAATCATACTTGAAGATGTG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation