Incidental Mutation 'R9010:Rims2'
| ID |
685595 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rims2
|
| Ensembl Gene |
ENSMUSG00000037386 |
| Gene Name |
regulating synaptic membrane exocytosis 2 |
| Synonyms |
RIM2, 2810036I15Rik, Syt3-rs |
| MMRRC Submission |
068840-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.661)
|
| Stock # |
R9010 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
39061681-39547768 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 39315786 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 597
(C597*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048719
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042917]
[ENSMUST00000082054]
[ENSMUST00000227243]
[ENSMUST00000228839]
|
| AlphaFold |
Q9EQZ7 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000042917
AA Change: C597*
|
| SMART Domains |
Protein: ENSMUSP00000048719
Gene: ENSMUSG00000037386
AA Change: C597*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
30 |
154 |
9.5e-18 |
PFAM |
|
low complexity region
|
315 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
498 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
521 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
540 |
N/A |
INTRINSIC |
|
PDZ
|
646 |
725 |
8.27e-16 |
SMART |
|
low complexity region
|
740 |
748 |
N/A |
INTRINSIC |
|
C2
|
790 |
897 |
4.08e-21 |
SMART |
|
low complexity region
|
905 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1130 |
N/A |
INTRINSIC |
|
low complexity region
|
1208 |
1238 |
N/A |
INTRINSIC |
|
C2
|
1432 |
1535 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000082054
AA Change: C637*
|
| SMART Domains |
Protein: ENSMUSP00000080711
Gene: ENSMUSG00000037386
AA Change: C637*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
76 |
194 |
2.2e-11 |
PFAM |
|
low complexity region
|
355 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
538 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
561 |
N/A |
INTRINSIC |
|
low complexity region
|
567 |
580 |
N/A |
INTRINSIC |
|
PDZ
|
686 |
765 |
8.27e-16 |
SMART |
|
low complexity region
|
780 |
788 |
N/A |
INTRINSIC |
|
C2
|
830 |
937 |
4.08e-21 |
SMART |
|
low complexity region
|
945 |
959 |
N/A |
INTRINSIC |
|
low complexity region
|
1075 |
1086 |
N/A |
INTRINSIC |
|
low complexity region
|
1166 |
1196 |
N/A |
INTRINSIC |
|
C2
|
1390 |
1493 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000227243
AA Change: C597*
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227381
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228839
|
| Meta Mutation Damage Score |
0.9631 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.1%
|
| Validation Efficiency |
100% (71/71) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]
PHENOTYPE: Mice homozygous for a knock-out allele show reduced body size, aberrant insulin granule exocytosis, and impaired secretion of hormones associated with glucose homeostasis. Mice homozygous for another knock-out allele show a slightly reduced body size, abnormal maternal behavior and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310003L06Rik |
T |
A |
5: 88,119,504 (GRCm39) |
M87K |
possibly damaging |
Het |
| Angel1 |
T |
C |
12: 86,770,153 (GRCm39) |
S36G |
possibly damaging |
Het |
| Apol6 |
A |
G |
15: 76,935,697 (GRCm39) |
H322R |
unknown |
Het |
| Arfgef2 |
G |
A |
2: 166,701,284 (GRCm39) |
R694Q |
probably damaging |
Het |
| Bank1 |
A |
T |
3: 135,761,559 (GRCm39) |
N748K |
probably benign |
Het |
| Bptf |
A |
T |
11: 106,964,576 (GRCm39) |
D1539E |
probably damaging |
Het |
| Bst1 |
T |
C |
5: 43,982,695 (GRCm39) |
I180T |
possibly damaging |
Het |
| Cabin1 |
C |
A |
10: 75,570,892 (GRCm39) |
E795* |
probably null |
Het |
| Ccdc168 |
A |
G |
1: 44,100,633 (GRCm39) |
V155A |
possibly damaging |
Het |
| Cckar |
T |
A |
5: 53,857,163 (GRCm39) |
T416S |
probably damaging |
Het |
| Ccng2 |
G |
T |
5: 93,416,616 (GRCm39) |
E46* |
probably null |
Het |
| Ceacam9 |
T |
C |
7: 16,455,916 (GRCm39) |
S8P |
probably benign |
Het |
| Cercam |
G |
A |
2: 29,766,071 (GRCm39) |
D317N |
possibly damaging |
Het |
| Cfap54 |
T |
A |
10: 92,734,921 (GRCm39) |
M2377L |
unknown |
Het |
| Cgnl1 |
A |
T |
9: 71,558,631 (GRCm39) |
L914H |
probably damaging |
Het |
| Chst13 |
G |
A |
6: 90,286,506 (GRCm39) |
P152L |
probably damaging |
Het |
| Clec2g |
T |
A |
6: 128,925,688 (GRCm39) |
F32L |
unknown |
Het |
| Cntnap5c |
A |
T |
17: 58,671,159 (GRCm39) |
M1116L |
probably benign |
Het |
| Col11a2 |
C |
A |
17: 34,283,760 (GRCm39) |
F1516L |
unknown |
Het |
| Crb2 |
A |
G |
2: 37,680,698 (GRCm39) |
E542G |
probably benign |
Het |
| Crisp1 |
A |
T |
17: 40,616,101 (GRCm39) |
|
probably benign |
Het |
| Crybg3 |
G |
A |
16: 59,374,702 (GRCm39) |
T470M |
probably damaging |
Het |
| Dusp9 |
TAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCTAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCTAAAGCGGAGGCCAAAGCGGAGGCCAAAG |
TAAAGCGGAGGCCAAAGCGGAGGCCAAAGCGGAGGCTAAAGCGGAGGCCAAAGCGGAGGCCAAAG |
X: 72,684,217 (GRCm39) |
|
probably benign |
Het |
| Eif1ad |
T |
A |
19: 5,418,726 (GRCm39) |
V93D |
possibly damaging |
Het |
| Entpd3 |
T |
C |
9: 120,384,825 (GRCm39) |
I134T |
probably benign |
Het |
| Garre1 |
A |
T |
7: 33,938,491 (GRCm39) |
C1015S |
probably benign |
Het |
| Gm19410 |
A |
G |
8: 36,282,011 (GRCm39) |
M1865V |
probably benign |
Het |
| Gpat2 |
A |
G |
2: 127,277,146 (GRCm39) |
E728G |
probably benign |
Het |
| Heatr5b |
C |
A |
17: 79,081,139 (GRCm39) |
S1371I |
probably damaging |
Het |
| Ighv1-4 |
A |
T |
12: 114,450,949 (GRCm39) |
M53K |
possibly damaging |
Het |
| Itch |
A |
T |
2: 155,020,991 (GRCm39) |
T169S |
probably benign |
Het |
| Kifc2 |
A |
G |
15: 76,550,885 (GRCm39) |
N587S |
possibly damaging |
Het |
| Klk1b16 |
A |
T |
7: 43,790,177 (GRCm39) |
D149V |
probably benign |
Het |
| Kndc1 |
C |
T |
7: 139,507,708 (GRCm39) |
S1222F |
possibly damaging |
Het |
| Lefty2 |
T |
A |
1: 180,722,172 (GRCm39) |
I170N |
probably damaging |
Het |
| Lrrc14b |
A |
G |
13: 74,509,151 (GRCm39) |
F419L |
possibly damaging |
Het |
| Mkrn2 |
T |
A |
6: 115,591,583 (GRCm39) |
V302E |
possibly damaging |
Het |
| Msh4 |
T |
C |
3: 153,595,819 (GRCm39) |
K271R |
probably benign |
Het |
| Muc6 |
T |
C |
7: 141,226,351 (GRCm39) |
T1559A |
unknown |
Het |
| Naa16 |
T |
G |
14: 79,607,482 (GRCm39) |
R289S |
probably benign |
Het |
| Nab1 |
T |
A |
1: 52,529,610 (GRCm39) |
I96F |
possibly damaging |
Het |
| Ntn4 |
T |
C |
10: 93,480,506 (GRCm39) |
C77R |
|
Het |
| Nusap1 |
A |
G |
2: 119,479,456 (GRCm39) |
T424A |
possibly damaging |
Het |
| Or1p1 |
G |
T |
11: 74,180,305 (GRCm39) |
V278F |
probably damaging |
Het |
| Or2w6 |
A |
G |
13: 21,842,681 (GRCm39) |
Y271H |
probably damaging |
Het |
| Or4e2 |
T |
A |
14: 52,688,556 (GRCm39) |
S229T |
possibly damaging |
Het |
| Otog |
A |
G |
7: 45,949,894 (GRCm39) |
D267G |
probably benign |
Het |
| P2ry2 |
A |
C |
7: 100,647,358 (GRCm39) |
F316V |
probably benign |
Het |
| Padi2 |
A |
G |
4: 140,663,924 (GRCm39) |
T426A |
probably damaging |
Het |
| Pakap |
A |
T |
4: 57,883,192 (GRCm39) |
D845V |
probably damaging |
Het |
| Plxna2 |
T |
C |
1: 194,471,217 (GRCm39) |
F996S |
possibly damaging |
Het |
| Ppp4r3a |
T |
C |
12: 101,024,591 (GRCm39) |
M303V |
possibly damaging |
Het |
| Prelid2 |
A |
T |
18: 42,065,781 (GRCm39) |
W85R |
probably damaging |
Het |
| Rabep1 |
G |
A |
11: 70,810,034 (GRCm39) |
R532H |
probably damaging |
Het |
| Rabgap1l |
G |
A |
1: 160,528,443 (GRCm39) |
R388W |
possibly damaging |
Het |
| Rad51ap2 |
G |
T |
12: 11,508,675 (GRCm39) |
V866L |
probably benign |
Het |
| Rassf3 |
C |
A |
10: 121,311,991 (GRCm39) |
E9* |
probably null |
Het |
| Rbbp4 |
A |
C |
4: 129,216,180 (GRCm39) |
L189R |
probably benign |
Het |
| Rrp12 |
T |
A |
19: 41,871,929 (GRCm39) |
I452F |
probably benign |
Het |
| Snx29 |
G |
A |
16: 11,449,391 (GRCm39) |
A279T |
probably benign |
Het |
| Tdh |
C |
T |
14: 63,737,704 (GRCm39) |
S17N |
probably benign |
Het |
| Tgm5 |
T |
C |
2: 120,879,371 (GRCm39) |
D555G |
possibly damaging |
Het |
| Thbs1 |
A |
C |
2: 117,953,045 (GRCm39) |
D885A |
probably damaging |
Het |
| Tmprss9 |
C |
A |
10: 80,733,701 (GRCm39) |
A921E |
unknown |
Het |
| Trrap |
T |
A |
5: 144,783,226 (GRCm39) |
F3340I |
probably damaging |
Het |
| Vmn1r72 |
A |
T |
7: 11,404,145 (GRCm39) |
M101K |
possibly damaging |
Het |
| Vmn2r117 |
A |
G |
17: 23,679,445 (GRCm39) |
L593P |
probably benign |
Het |
| Washc2 |
G |
A |
6: 116,198,823 (GRCm39) |
G295E |
probably damaging |
Het |
| Zfp273 |
A |
T |
13: 67,974,177 (GRCm39) |
H435L |
probably damaging |
Het |
| Zfp395 |
A |
G |
14: 65,623,948 (GRCm39) |
E139G |
possibly damaging |
Het |
| Zfp512b |
G |
A |
2: 181,230,011 (GRCm39) |
A552V |
possibly damaging |
Het |
|
| Other mutations in Rims2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Rims2
|
APN |
15 |
39,323,011 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL00502:Rims2
|
APN |
15 |
39,370,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00556:Rims2
|
APN |
15 |
39,320,070 (GRCm39) |
splice site |
probably null |
|
|
IGL00811:Rims2
|
APN |
15 |
39,155,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00827:Rims2
|
APN |
15 |
39,335,755 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01642:Rims2
|
APN |
15 |
39,321,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Rims2
|
APN |
15 |
39,398,334 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03009:Rims2
|
APN |
15 |
39,430,393 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03080:Rims2
|
APN |
15 |
39,399,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Rims2
|
APN |
15 |
39,322,989 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03252:Rims2
|
APN |
15 |
39,315,748 (GRCm39) |
missense |
probably benign |
|
|
IGL03365:Rims2
|
APN |
15 |
39,339,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03393:Rims2
|
APN |
15 |
39,326,009 (GRCm39) |
splice site |
probably null |
|
|
IGL03409:Rims2
|
APN |
15 |
39,320,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
rhyme
|
UTSW |
15 |
39,315,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4486001:Rims2
|
UTSW |
15 |
39,339,916 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0009:Rims2
|
UTSW |
15 |
39,398,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0009:Rims2
|
UTSW |
15 |
39,398,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0078:Rims2
|
UTSW |
15 |
39,398,251 (GRCm39) |
missense |
probably benign |
0.42 |
|
R0367:Rims2
|
UTSW |
15 |
39,326,011 (GRCm39) |
splice site |
probably null |
|
|
R0401:Rims2
|
UTSW |
15 |
39,373,028 (GRCm39) |
splice site |
probably benign |
|
|
R0531:Rims2
|
UTSW |
15 |
39,430,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0791:Rims2
|
UTSW |
15 |
39,543,021 (GRCm39) |
splice site |
probably benign |
|
|
R0838:Rims2
|
UTSW |
15 |
39,544,421 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1201:Rims2
|
UTSW |
15 |
39,479,720 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1318:Rims2
|
UTSW |
15 |
39,381,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1457:Rims2
|
UTSW |
15 |
39,374,710 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1619:Rims2
|
UTSW |
15 |
39,370,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1672:Rims2
|
UTSW |
15 |
39,155,584 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1743:Rims2
|
UTSW |
15 |
39,543,046 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1766:Rims2
|
UTSW |
15 |
39,325,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1779:Rims2
|
UTSW |
15 |
39,545,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1804:Rims2
|
UTSW |
15 |
39,300,439 (GRCm39) |
nonsense |
probably null |
|
|
R1985:Rims2
|
UTSW |
15 |
39,208,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1986:Rims2
|
UTSW |
15 |
39,208,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2113:Rims2
|
UTSW |
15 |
39,374,722 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2260:Rims2
|
UTSW |
15 |
39,341,962 (GRCm39) |
nonsense |
probably null |
|
|
R2510:Rims2
|
UTSW |
15 |
39,449,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3693:Rims2
|
UTSW |
15 |
39,341,971 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3937:Rims2
|
UTSW |
15 |
39,301,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4425:Rims2
|
UTSW |
15 |
39,301,320 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4453:Rims2
|
UTSW |
15 |
39,155,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Rims2
|
UTSW |
15 |
39,325,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4518:Rims2
|
UTSW |
15 |
39,300,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4526:Rims2
|
UTSW |
15 |
39,301,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4833:Rims2
|
UTSW |
15 |
39,399,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4936:Rims2
|
UTSW |
15 |
39,301,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4993:Rims2
|
UTSW |
15 |
39,317,841 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5001:Rims2
|
UTSW |
15 |
39,315,824 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5054:Rims2
|
UTSW |
15 |
39,381,265 (GRCm39) |
splice site |
probably null |
|
|
R5072:Rims2
|
UTSW |
15 |
39,325,986 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5171:Rims2
|
UTSW |
15 |
39,300,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5429:Rims2
|
UTSW |
15 |
39,208,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5623:Rims2
|
UTSW |
15 |
39,342,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5624:Rims2
|
UTSW |
15 |
39,208,809 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5685:Rims2
|
UTSW |
15 |
39,300,602 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5784:Rims2
|
UTSW |
15 |
39,399,383 (GRCm39) |
splice site |
probably null |
|
|
R5790:Rims2
|
UTSW |
15 |
39,544,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5822:Rims2
|
UTSW |
15 |
39,339,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5963:Rims2
|
UTSW |
15 |
39,300,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Rims2
|
UTSW |
15 |
39,155,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6057:Rims2
|
UTSW |
15 |
39,538,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Rims2
|
UTSW |
15 |
39,061,758 (GRCm39) |
start codon destroyed |
unknown |
|
|
R6407:Rims2
|
UTSW |
15 |
39,315,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6418:Rims2
|
UTSW |
15 |
39,373,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6495:Rims2
|
UTSW |
15 |
39,381,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6502:Rims2
|
UTSW |
15 |
39,398,251 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6753:Rims2
|
UTSW |
15 |
39,430,369 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6855:Rims2
|
UTSW |
15 |
39,208,911 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6948:Rims2
|
UTSW |
15 |
39,374,737 (GRCm39) |
missense |
probably benign |
|
|
R7058:Rims2
|
UTSW |
15 |
39,449,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Rims2
|
UTSW |
15 |
39,300,473 (GRCm39) |
missense |
probably benign |
|
|
R7217:Rims2
|
UTSW |
15 |
39,339,885 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7223:Rims2
|
UTSW |
15 |
39,300,428 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7289:Rims2
|
UTSW |
15 |
39,301,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7459:Rims2
|
UTSW |
15 |
39,381,235 (GRCm39) |
missense |
probably benign |
|
|
R7663:Rims2
|
UTSW |
15 |
39,370,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7792:Rims2
|
UTSW |
15 |
39,061,923 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7836:Rims2
|
UTSW |
15 |
39,544,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8082:Rims2
|
UTSW |
15 |
39,339,919 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8489:Rims2
|
UTSW |
15 |
39,479,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8730:Rims2
|
UTSW |
15 |
39,381,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8830:Rims2
|
UTSW |
15 |
39,300,758 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8857:Rims2
|
UTSW |
15 |
39,543,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8893:Rims2
|
UTSW |
15 |
39,398,350 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9030:Rims2
|
UTSW |
15 |
39,339,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9287:Rims2
|
UTSW |
15 |
39,543,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9395:Rims2
|
UTSW |
15 |
39,155,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Rims2
|
UTSW |
15 |
39,300,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9506:Rims2
|
UTSW |
15 |
39,335,832 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0034:Rims2
|
UTSW |
15 |
39,300,930 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,544,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rims2
|
UTSW |
15 |
39,342,086 (GRCm39) |
frame shift |
probably null |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,301,165 (GRCm39) |
missense |
probably benign |
0.24 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCACACTTGTAGGGGACAGTC -3'
(R):5'- GGGTGTGCTGTCTATTAACAAG -3'
Sequencing Primer
(F):5'- TCACACTTGTAGGGGACAGTCAAAAG -3'
(R):5'- GGTGTGCTGTCTATTAACAAGAACAG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation