Incidental Mutation 'R9014:Dennd4c'
| ID |
685821 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4c
|
| Ensembl Gene |
ENSMUSG00000038024 |
| Gene Name |
DENN domain containing 4C |
| Synonyms |
1700065A05Rik |
| MMRRC Submission |
068844-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9014 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
86666792-86768840 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 86754666 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Leucine
at position 1559
(I1559L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123367
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000082026]
[ENSMUST00000142837]
|
| AlphaFold |
A6H8H2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082026
AA Change: I1608L
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000080685
Gene: ENSMUSG00000038024
AA Change: I1608L
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
3.19e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
983 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1052 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1724 |
1739 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000142837
AA Change: I1559L
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000123367
Gene: ENSMUSG00000038024
AA Change: I1559L
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
2.68e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
934 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
964 |
976 |
N/A |
INTRINSIC |
|
low complexity region
|
996 |
1003 |
N/A |
INTRINSIC |
|
low complexity region
|
1053 |
1064 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1343 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1437 |
N/A |
INTRINSIC |
|
low complexity region
|
1675 |
1690 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aco2 |
A |
G |
15: 81,798,857 (GRCm39) |
N746S |
probably benign |
Het |
| Ahnak2 |
T |
C |
12: 112,740,170 (GRCm39) |
T1301A |
possibly damaging |
Het |
| Akap6 |
T |
A |
12: 53,186,403 (GRCm39) |
N1272K |
possibly damaging |
Het |
| Apc |
G |
T |
18: 34,354,074 (GRCm39) |
|
probably benign |
Het |
| Arap1 |
A |
G |
7: 101,053,540 (GRCm39) |
S1290G |
probably damaging |
Het |
| Arhgef25 |
T |
C |
10: 127,019,607 (GRCm39) |
Y483C |
probably damaging |
Het |
| Arpp21 |
G |
T |
9: 112,006,796 (GRCm39) |
Q138K |
probably damaging |
Het |
| Bahcc1 |
C |
T |
11: 120,163,715 (GRCm39) |
A671V |
probably benign |
Het |
| Bahcc1 |
T |
C |
11: 120,173,048 (GRCm39) |
S1557P |
probably benign |
Het |
| Bltp2 |
T |
C |
11: 78,160,488 (GRCm39) |
L649P |
possibly damaging |
Het |
| Brca2 |
C |
A |
5: 150,465,219 (GRCm39) |
T1661K |
probably benign |
Het |
| Casq1 |
T |
A |
1: 172,038,064 (GRCm39) |
S356C |
probably damaging |
Het |
| Catsperg1 |
T |
C |
7: 28,906,066 (GRCm39) |
Y171C |
probably damaging |
Het |
| Ccdc88c |
G |
C |
12: 100,879,323 (GRCm39) |
Q1926E |
probably benign |
Het |
| Cdc42bpg |
T |
A |
19: 6,372,289 (GRCm39) |
M1425K |
possibly damaging |
Het |
| Chac2 |
C |
T |
11: 30,936,158 (GRCm39) |
R30Q |
probably damaging |
Het |
| Clca3a1 |
T |
C |
3: 144,442,731 (GRCm39) |
D771G |
probably benign |
Het |
| Cyp26c1 |
T |
C |
19: 37,675,844 (GRCm39) |
|
probably null |
Het |
| Dcaf8 |
T |
C |
1: 172,007,530 (GRCm39) |
V333A |
possibly damaging |
Het |
| Dgcr8 |
T |
G |
16: 18,077,514 (GRCm39) |
H632P |
possibly damaging |
Het |
| Dhx16 |
C |
A |
17: 36,193,490 (GRCm39) |
R278S |
probably benign |
Het |
| Dsel |
A |
T |
1: 111,788,509 (GRCm39) |
Y675* |
probably null |
Het |
| Dsp |
T |
C |
13: 38,376,700 (GRCm39) |
I1495T |
possibly damaging |
Het |
| Fam227a |
T |
A |
15: 79,504,958 (GRCm39) |
N495I |
possibly damaging |
Het |
| Fcgbpl1 |
A |
G |
7: 27,854,876 (GRCm39) |
E1834G |
probably damaging |
Het |
| Focad |
T |
A |
4: 88,275,763 (GRCm39) |
M1124K |
unknown |
Het |
| Foxi3 |
A |
G |
6: 70,937,815 (GRCm39) |
H349R |
probably damaging |
Het |
| Foxp1 |
TTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG |
TTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG |
6: 99,052,866 (GRCm39) |
|
probably benign |
Het |
| Fsip2 |
C |
A |
2: 82,806,898 (GRCm39) |
D1072E |
probably benign |
Het |
| Fsip2 |
T |
G |
2: 82,817,075 (GRCm39) |
H4269Q |
possibly damaging |
Het |
| Fzd10 |
C |
G |
5: 128,679,369 (GRCm39) |
P363R |
probably damaging |
Het |
| Gm49383 |
A |
C |
12: 69,243,425 (GRCm39) |
Y151* |
probably null |
Het |
| Ighv1-26 |
T |
A |
12: 114,752,033 (GRCm39) |
S104C |
probably damaging |
Het |
| Kat6a |
A |
G |
8: 23,430,087 (GRCm39) |
N1814S |
unknown |
Het |
| Kif18a |
T |
A |
2: 109,123,414 (GRCm39) |
H229Q |
probably damaging |
Het |
| Klk1b4 |
C |
T |
7: 43,859,098 (GRCm39) |
R39C |
probably benign |
Het |
| Lgr6 |
T |
C |
1: 134,931,248 (GRCm39) |
I269V |
probably damaging |
Het |
| Lrtm2 |
A |
G |
6: 119,294,219 (GRCm39) |
V304A |
probably damaging |
Het |
| Lsm8 |
A |
G |
6: 18,853,632 (GRCm39) |
D78G |
possibly damaging |
Het |
| Mroh2b |
T |
C |
15: 4,928,670 (GRCm39) |
M1T |
probably null |
Het |
| Ms4a14 |
T |
C |
19: 11,278,871 (GRCm39) |
E1229G |
possibly damaging |
Het |
| Nbeal1 |
G |
A |
1: 60,329,118 (GRCm39) |
D2179N |
probably damaging |
Het |
| Nfix |
G |
A |
8: 85,448,405 (GRCm39) |
T366M |
possibly damaging |
Het |
| Or12j4 |
A |
T |
7: 140,045,883 (GRCm39) |
|
probably benign |
Het |
| Or56b1b |
A |
G |
7: 108,164,882 (GRCm39) |
L40P |
possibly damaging |
Het |
| Or8b49 |
T |
C |
9: 38,506,123 (GRCm39) |
V202A |
probably damaging |
Het |
| Or8h9 |
T |
A |
2: 86,789,035 (GRCm39) |
I256F |
probably benign |
Het |
| Pear1 |
T |
C |
3: 87,658,479 (GRCm39) |
Q964R |
probably benign |
Het |
| Pgk2 |
T |
G |
17: 40,518,687 (GRCm39) |
E247A |
probably benign |
Het |
| Ppfia2 |
C |
T |
10: 106,763,666 (GRCm39) |
P1220S |
probably benign |
Het |
| Ppp1r1b |
T |
C |
11: 98,241,449 (GRCm39) |
S46P |
probably damaging |
Het |
| Ppp2ca |
C |
A |
11: 52,009,510 (GRCm39) |
H167Q |
probably damaging |
Het |
| Scel |
A |
T |
14: 103,822,575 (GRCm39) |
R396S |
probably benign |
Het |
| Siae |
T |
C |
9: 37,557,639 (GRCm39) |
V482A |
possibly damaging |
Het |
| Skint2 |
A |
G |
4: 112,483,026 (GRCm39) |
M144V |
probably benign |
Het |
| Slc23a3 |
A |
G |
1: 75,109,274 (GRCm39) |
F219L |
probably benign |
Het |
| Slc4a4 |
G |
T |
5: 89,280,245 (GRCm39) |
A348S |
probably damaging |
Het |
| Spin1 |
G |
T |
13: 51,282,010 (GRCm39) |
|
probably null |
Het |
| Tab2 |
G |
A |
10: 7,794,920 (GRCm39) |
R521W |
probably damaging |
Het |
| Tas2r118 |
G |
A |
6: 23,970,049 (GRCm39) |
T4M |
probably benign |
Het |
| Tet2 |
T |
A |
3: 133,172,949 (GRCm39) |
D1771V |
probably damaging |
Het |
| Tmprss15 |
T |
C |
16: 78,872,691 (GRCm39) |
T172A |
probably benign |
Het |
| Trav7-6 |
A |
G |
14: 53,954,604 (GRCm39) |
K65E |
probably benign |
Het |
| Txnrd3 |
A |
G |
6: 89,631,091 (GRCm39) |
Y129C |
probably damaging |
Het |
| Ulk4 |
A |
G |
9: 121,017,294 (GRCm39) |
I728T |
probably benign |
Het |
| Vmn1r44 |
G |
A |
6: 89,870,997 (GRCm39) |
V248M |
possibly damaging |
Het |
| Wdr64 |
A |
G |
1: 175,526,395 (GRCm39) |
I15V |
probably benign |
Het |
| Zdhhc17 |
T |
C |
10: 110,785,544 (GRCm39) |
T423A |
probably benign |
Het |
| Zfp619 |
T |
C |
7: 39,187,246 (GRCm39) |
I1092T |
probably benign |
Het |
| Zfp729b |
A |
T |
13: 67,740,274 (GRCm39) |
Y664N |
probably damaging |
Het |
|
| Other mutations in Dennd4c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01309:Dennd4c
|
APN |
4 |
86,723,724 (GRCm39) |
splice site |
probably benign |
|
|
IGL01810:Dennd4c
|
APN |
4 |
86,717,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02203:Dennd4c
|
APN |
4 |
86,721,173 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02217:Dennd4c
|
APN |
4 |
86,732,036 (GRCm39) |
missense |
probably benign |
|
|
IGL02236:Dennd4c
|
APN |
4 |
86,725,672 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02256:Dennd4c
|
APN |
4 |
86,717,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02396:Dennd4c
|
APN |
4 |
86,743,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02523:Dennd4c
|
APN |
4 |
86,692,490 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02615:Dennd4c
|
APN |
4 |
86,739,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03069:Dennd4c
|
APN |
4 |
86,692,674 (GRCm39) |
nonsense |
probably null |
|
|
IGL03116:Dennd4c
|
APN |
4 |
86,707,057 (GRCm39) |
splice site |
probably benign |
|
|
IGL03117:Dennd4c
|
APN |
4 |
86,696,140 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03273:Dennd4c
|
APN |
4 |
86,696,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03329:Dennd4c
|
APN |
4 |
86,696,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03365:Dennd4c
|
APN |
4 |
86,725,663 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
PIT4486001:Dennd4c
|
UTSW |
4 |
86,717,701 (GRCm39) |
nonsense |
probably null |
|
|
R0010:Dennd4c
|
UTSW |
4 |
86,699,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Dennd4c
|
UTSW |
4 |
86,746,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0032:Dennd4c
|
UTSW |
4 |
86,746,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0092:Dennd4c
|
UTSW |
4 |
86,699,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0103:Dennd4c
|
UTSW |
4 |
86,730,683 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0103:Dennd4c
|
UTSW |
4 |
86,730,683 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0511:Dennd4c
|
UTSW |
4 |
86,744,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0515:Dennd4c
|
UTSW |
4 |
86,731,703 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0578:Dennd4c
|
UTSW |
4 |
86,730,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0759:Dennd4c
|
UTSW |
4 |
86,707,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0784:Dennd4c
|
UTSW |
4 |
86,763,145 (GRCm39) |
missense |
probably benign |
0.37 |
|
R1156:Dennd4c
|
UTSW |
4 |
86,725,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1370:Dennd4c
|
UTSW |
4 |
86,729,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Dennd4c
|
UTSW |
4 |
86,692,769 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1569:Dennd4c
|
UTSW |
4 |
86,704,331 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1747:Dennd4c
|
UTSW |
4 |
86,725,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Dennd4c
|
UTSW |
4 |
86,721,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Dennd4c
|
UTSW |
4 |
86,743,415 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1997:Dennd4c
|
UTSW |
4 |
86,755,634 (GRCm39) |
missense |
probably benign |
|
|
R2244:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2348:Dennd4c
|
UTSW |
4 |
86,729,764 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2968:Dennd4c
|
UTSW |
4 |
86,699,881 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3033:Dennd4c
|
UTSW |
4 |
86,743,557 (GRCm39) |
small deletion |
probably benign |
|
|
R3401:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3402:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3403:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Dennd4c
|
UTSW |
4 |
86,698,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3939:Dennd4c
|
UTSW |
4 |
86,692,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4164:Dennd4c
|
UTSW |
4 |
86,725,764 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4384:Dennd4c
|
UTSW |
4 |
86,729,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4435:Dennd4c
|
UTSW |
4 |
86,716,312 (GRCm39) |
missense |
probably benign |
0.44 |
|
R4788:Dennd4c
|
UTSW |
4 |
86,738,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4801:Dennd4c
|
UTSW |
4 |
86,738,121 (GRCm39) |
nonsense |
probably null |
|
|
R4802:Dennd4c
|
UTSW |
4 |
86,738,121 (GRCm39) |
nonsense |
probably null |
|
|
R4818:Dennd4c
|
UTSW |
4 |
86,743,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4923:Dennd4c
|
UTSW |
4 |
86,725,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4958:Dennd4c
|
UTSW |
4 |
86,699,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5025:Dennd4c
|
UTSW |
4 |
86,713,536 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5434:Dennd4c
|
UTSW |
4 |
86,729,693 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5662:Dennd4c
|
UTSW |
4 |
86,713,525 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5802:Dennd4c
|
UTSW |
4 |
86,729,690 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5849:Dennd4c
|
UTSW |
4 |
86,744,223 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5861:Dennd4c
|
UTSW |
4 |
86,709,589 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5970:Dennd4c
|
UTSW |
4 |
86,743,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6163:Dennd4c
|
UTSW |
4 |
86,723,828 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6356:Dennd4c
|
UTSW |
4 |
86,743,686 (GRCm39) |
missense |
probably benign |
|
|
R6661:Dennd4c
|
UTSW |
4 |
86,717,626 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6855:Dennd4c
|
UTSW |
4 |
86,754,694 (GRCm39) |
missense |
probably benign |
|
|
R6983:Dennd4c
|
UTSW |
4 |
86,717,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Dennd4c
|
UTSW |
4 |
86,730,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7126:Dennd4c
|
UTSW |
4 |
86,725,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7185:Dennd4c
|
UTSW |
4 |
86,729,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7212:Dennd4c
|
UTSW |
4 |
86,721,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7324:Dennd4c
|
UTSW |
4 |
86,747,975 (GRCm39) |
missense |
unknown |
|
|
R7329:Dennd4c
|
UTSW |
4 |
86,759,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7329:Dennd4c
|
UTSW |
4 |
86,698,111 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7466:Dennd4c
|
UTSW |
4 |
86,692,568 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7479:Dennd4c
|
UTSW |
4 |
86,717,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7538:Dennd4c
|
UTSW |
4 |
86,692,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7599:Dennd4c
|
UTSW |
4 |
86,729,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7688:Dennd4c
|
UTSW |
4 |
86,713,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7725:Dennd4c
|
UTSW |
4 |
86,704,330 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7751:Dennd4c
|
UTSW |
4 |
86,747,179 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7790:Dennd4c
|
UTSW |
4 |
86,717,754 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8056:Dennd4c
|
UTSW |
4 |
86,763,213 (GRCm39) |
missense |
probably null |
0.71 |
|
R8307:Dennd4c
|
UTSW |
4 |
86,744,109 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8494:Dennd4c
|
UTSW |
4 |
86,759,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Dennd4c
|
UTSW |
4 |
86,744,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9014:Dennd4c
|
UTSW |
4 |
86,739,702 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9017:Dennd4c
|
UTSW |
4 |
86,743,349 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9142:Dennd4c
|
UTSW |
4 |
86,755,637 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9224:Dennd4c
|
UTSW |
4 |
86,738,170 (GRCm39) |
nonsense |
probably null |
|
|
R9570:Dennd4c
|
UTSW |
4 |
86,747,208 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9644:Dennd4c
|
UTSW |
4 |
86,713,363 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9649:Dennd4c
|
UTSW |
4 |
86,743,160 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9658:Dennd4c
|
UTSW |
4 |
86,754,625 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTGAGGACATGGGGATTTAAGC -3'
(R):5'- AGGAATACTGCATTTCTCTTCTTACAG -3'
Sequencing Primer
(F):5'- TGGCTCACATCTTTAAGGCAGAG -3'
(R):5'- TCTTACAGTGAACTCTACGAACTC -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation