Incidental Mutation 'R9014:Foxp1'
| ID |
685832 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Foxp1
|
| Ensembl Gene |
ENSMUSG00000030067 |
| Gene Name |
forkhead box P1 |
| Synonyms |
3110052D19Rik, 4932443N09Rik |
| MMRRC Submission |
068844-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9014 (G1)
|
| Quality Score |
129.467 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
98902299-99499682 bp(-) (GRCm39) |
| Type of Mutation |
small deletion (1 aa in frame mutation) |
| DNA Base Change (assembly) |
TTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG to TTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGTTGCTGCTGCTGTTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGTTGCTGCTGCTG
at 99052866 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135764
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074346]
[ENSMUST00000113322]
[ENSMUST00000113324]
[ENSMUST00000113326]
[ENSMUST00000113328]
[ENSMUST00000113329]
[ENSMUST00000175886]
[ENSMUST00000176565]
[ENSMUST00000176632]
[ENSMUST00000176850]
[ENSMUST00000177208]
[ENSMUST00000177230]
[ENSMUST00000177307]
|
| AlphaFold |
P58462 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074346
|
| SMART Domains |
Protein: ENSMUSP00000073953
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113322
|
| SMART Domains |
Protein: ENSMUSP00000108948
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113324
|
| SMART Domains |
Protein: ENSMUSP00000108950
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113326
|
| SMART Domains |
Protein: ENSMUSP00000108952
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
218 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
298 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
302 |
327 |
8.67e-1 |
SMART |
|
low complexity region
|
339 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
414 |
N/A |
INTRINSIC |
|
FH
|
459 |
540 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113328
|
| SMART Domains |
Protein: ENSMUSP00000108954
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113329
|
| SMART Domains |
Protein: ENSMUSP00000108955
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
579 |
1.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175886
|
| SMART Domains |
Protein: ENSMUSP00000135517
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
71 |
105 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176565
|
| SMART Domains |
Protein: ENSMUSP00000135181
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176632
|
| SMART Domains |
Protein: ENSMUSP00000135635
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
202 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
219 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
244 |
N/A |
INTRINSIC |
|
low complexity region
|
286 |
299 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
303 |
328 |
8.67e-1 |
SMART |
|
low complexity region
|
340 |
352 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
415 |
N/A |
INTRINSIC |
|
FH
|
460 |
541 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176850
|
| SMART Domains |
Protein: ENSMUSP00000135041
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177208
|
| SMART Domains |
Protein: ENSMUSP00000135187
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
88 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177230
|
| SMART Domains |
Protein: ENSMUSP00000135098
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177307
|
| SMART Domains |
Protein: ENSMUSP00000135764
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
235 |
N/A |
INTRINSIC |
|
low complexity region
|
238 |
252 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
277 |
N/A |
INTRINSIC |
|
low complexity region
|
319 |
332 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
336 |
361 |
8.67e-1 |
SMART |
|
low complexity region
|
373 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
448 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display embryonic lethality with abnormal outflow tract septation, ventricular septal defects, abnormal cardiac valve morphology, decreased and irregular heart rate, thin ventricular compact zone, and edema. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aco2 |
A |
G |
15: 81,798,857 (GRCm39) |
N746S |
probably benign |
Het |
| Ahnak2 |
T |
C |
12: 112,740,170 (GRCm39) |
T1301A |
possibly damaging |
Het |
| Akap6 |
T |
A |
12: 53,186,403 (GRCm39) |
N1272K |
possibly damaging |
Het |
| Apc |
G |
T |
18: 34,354,074 (GRCm39) |
|
probably benign |
Het |
| Arap1 |
A |
G |
7: 101,053,540 (GRCm39) |
S1290G |
probably damaging |
Het |
| Arhgef25 |
T |
C |
10: 127,019,607 (GRCm39) |
Y483C |
probably damaging |
Het |
| Arpp21 |
G |
T |
9: 112,006,796 (GRCm39) |
Q138K |
probably damaging |
Het |
| Bahcc1 |
C |
T |
11: 120,163,715 (GRCm39) |
A671V |
probably benign |
Het |
| Bahcc1 |
T |
C |
11: 120,173,048 (GRCm39) |
S1557P |
probably benign |
Het |
| Bltp2 |
T |
C |
11: 78,160,488 (GRCm39) |
L649P |
possibly damaging |
Het |
| Brca2 |
C |
A |
5: 150,465,219 (GRCm39) |
T1661K |
probably benign |
Het |
| Casq1 |
T |
A |
1: 172,038,064 (GRCm39) |
S356C |
probably damaging |
Het |
| Catsperg1 |
T |
C |
7: 28,906,066 (GRCm39) |
Y171C |
probably damaging |
Het |
| Ccdc88c |
G |
C |
12: 100,879,323 (GRCm39) |
Q1926E |
probably benign |
Het |
| Cdc42bpg |
T |
A |
19: 6,372,289 (GRCm39) |
M1425K |
possibly damaging |
Het |
| Chac2 |
C |
T |
11: 30,936,158 (GRCm39) |
R30Q |
probably damaging |
Het |
| Clca3a1 |
T |
C |
3: 144,442,731 (GRCm39) |
D771G |
probably benign |
Het |
| Cyp26c1 |
T |
C |
19: 37,675,844 (GRCm39) |
|
probably null |
Het |
| Dcaf8 |
T |
C |
1: 172,007,530 (GRCm39) |
V333A |
possibly damaging |
Het |
| Dennd4c |
G |
A |
4: 86,739,702 (GRCm39) |
S997N |
probably benign |
Het |
| Dennd4c |
A |
C |
4: 86,754,666 (GRCm39) |
I1559L |
probably benign |
Het |
| Dgcr8 |
T |
G |
16: 18,077,514 (GRCm39) |
H632P |
possibly damaging |
Het |
| Dhx16 |
C |
A |
17: 36,193,490 (GRCm39) |
R278S |
probably benign |
Het |
| Dsel |
A |
T |
1: 111,788,509 (GRCm39) |
Y675* |
probably null |
Het |
| Dsp |
T |
C |
13: 38,376,700 (GRCm39) |
I1495T |
possibly damaging |
Het |
| Fam227a |
T |
A |
15: 79,504,958 (GRCm39) |
N495I |
possibly damaging |
Het |
| Fcgbpl1 |
A |
G |
7: 27,854,876 (GRCm39) |
E1834G |
probably damaging |
Het |
| Focad |
T |
A |
4: 88,275,763 (GRCm39) |
M1124K |
unknown |
Het |
| Foxi3 |
A |
G |
6: 70,937,815 (GRCm39) |
H349R |
probably damaging |
Het |
| Fsip2 |
C |
A |
2: 82,806,898 (GRCm39) |
D1072E |
probably benign |
Het |
| Fsip2 |
T |
G |
2: 82,817,075 (GRCm39) |
H4269Q |
possibly damaging |
Het |
| Fzd10 |
C |
G |
5: 128,679,369 (GRCm39) |
P363R |
probably damaging |
Het |
| Gm49383 |
A |
C |
12: 69,243,425 (GRCm39) |
Y151* |
probably null |
Het |
| Ighv1-26 |
T |
A |
12: 114,752,033 (GRCm39) |
S104C |
probably damaging |
Het |
| Kat6a |
A |
G |
8: 23,430,087 (GRCm39) |
N1814S |
unknown |
Het |
| Kif18a |
T |
A |
2: 109,123,414 (GRCm39) |
H229Q |
probably damaging |
Het |
| Klk1b4 |
C |
T |
7: 43,859,098 (GRCm39) |
R39C |
probably benign |
Het |
| Lgr6 |
T |
C |
1: 134,931,248 (GRCm39) |
I269V |
probably damaging |
Het |
| Lrtm2 |
A |
G |
6: 119,294,219 (GRCm39) |
V304A |
probably damaging |
Het |
| Lsm8 |
A |
G |
6: 18,853,632 (GRCm39) |
D78G |
possibly damaging |
Het |
| Mroh2b |
T |
C |
15: 4,928,670 (GRCm39) |
M1T |
probably null |
Het |
| Ms4a14 |
T |
C |
19: 11,278,871 (GRCm39) |
E1229G |
possibly damaging |
Het |
| Nbeal1 |
G |
A |
1: 60,329,118 (GRCm39) |
D2179N |
probably damaging |
Het |
| Nfix |
G |
A |
8: 85,448,405 (GRCm39) |
T366M |
possibly damaging |
Het |
| Or12j4 |
A |
T |
7: 140,045,883 (GRCm39) |
|
probably benign |
Het |
| Or56b1b |
A |
G |
7: 108,164,882 (GRCm39) |
L40P |
possibly damaging |
Het |
| Or8b49 |
T |
C |
9: 38,506,123 (GRCm39) |
V202A |
probably damaging |
Het |
| Or8h9 |
T |
A |
2: 86,789,035 (GRCm39) |
I256F |
probably benign |
Het |
| Pear1 |
T |
C |
3: 87,658,479 (GRCm39) |
Q964R |
probably benign |
Het |
| Pgk2 |
T |
G |
17: 40,518,687 (GRCm39) |
E247A |
probably benign |
Het |
| Ppfia2 |
C |
T |
10: 106,763,666 (GRCm39) |
P1220S |
probably benign |
Het |
| Ppp1r1b |
T |
C |
11: 98,241,449 (GRCm39) |
S46P |
probably damaging |
Het |
| Ppp2ca |
C |
A |
11: 52,009,510 (GRCm39) |
H167Q |
probably damaging |
Het |
| Scel |
A |
T |
14: 103,822,575 (GRCm39) |
R396S |
probably benign |
Het |
| Siae |
T |
C |
9: 37,557,639 (GRCm39) |
V482A |
possibly damaging |
Het |
| Skint2 |
A |
G |
4: 112,483,026 (GRCm39) |
M144V |
probably benign |
Het |
| Slc23a3 |
A |
G |
1: 75,109,274 (GRCm39) |
F219L |
probably benign |
Het |
| Slc4a4 |
G |
T |
5: 89,280,245 (GRCm39) |
A348S |
probably damaging |
Het |
| Spin1 |
G |
T |
13: 51,282,010 (GRCm39) |
|
probably null |
Het |
| Tab2 |
G |
A |
10: 7,794,920 (GRCm39) |
R521W |
probably damaging |
Het |
| Tas2r118 |
G |
A |
6: 23,970,049 (GRCm39) |
T4M |
probably benign |
Het |
| Tet2 |
T |
A |
3: 133,172,949 (GRCm39) |
D1771V |
probably damaging |
Het |
| Tmprss15 |
T |
C |
16: 78,872,691 (GRCm39) |
T172A |
probably benign |
Het |
| Trav7-6 |
A |
G |
14: 53,954,604 (GRCm39) |
K65E |
probably benign |
Het |
| Txnrd3 |
A |
G |
6: 89,631,091 (GRCm39) |
Y129C |
probably damaging |
Het |
| Ulk4 |
A |
G |
9: 121,017,294 (GRCm39) |
I728T |
probably benign |
Het |
| Vmn1r44 |
G |
A |
6: 89,870,997 (GRCm39) |
V248M |
possibly damaging |
Het |
| Wdr64 |
A |
G |
1: 175,526,395 (GRCm39) |
I15V |
probably benign |
Het |
| Zdhhc17 |
T |
C |
10: 110,785,544 (GRCm39) |
T423A |
probably benign |
Het |
| Zfp619 |
T |
C |
7: 39,187,246 (GRCm39) |
I1092T |
probably benign |
Het |
| Zfp729b |
A |
T |
13: 67,740,274 (GRCm39) |
Y664N |
probably damaging |
Het |
|
| Other mutations in Foxp1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02191:Foxp1
|
APN |
6 |
98,922,561 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02330:Foxp1
|
APN |
6 |
98,922,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02869:Foxp1
|
APN |
6 |
98,907,044 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL02968:Foxp1
|
APN |
6 |
99,052,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Foxy
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
Moxie
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Roxie
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R0037:Foxp1
|
UTSW |
6 |
99,139,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0427:Foxp1
|
UTSW |
6 |
98,907,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0601:Foxp1
|
UTSW |
6 |
98,907,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1356:Foxp1
|
UTSW |
6 |
98,993,637 (GRCm39) |
splice site |
probably benign |
|
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1548:Foxp1
|
UTSW |
6 |
98,922,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1696:Foxp1
|
UTSW |
6 |
98,922,663 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1933:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R2152:Foxp1
|
UTSW |
6 |
98,993,502 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2338:Foxp1
|
UTSW |
6 |
98,980,254 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R3896:Foxp1
|
UTSW |
6 |
99,052,897 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5006:Foxp1
|
UTSW |
6 |
99,139,819 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5143:Foxp1
|
UTSW |
6 |
98,922,493 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5428:Foxp1
|
UTSW |
6 |
98,993,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5765:Foxp1
|
UTSW |
6 |
98,992,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5816:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6175:Foxp1
|
UTSW |
6 |
98,943,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6776:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6782:Foxp1
|
UTSW |
6 |
98,907,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7229:Foxp1
|
UTSW |
6 |
98,912,373 (GRCm39) |
missense |
unknown |
|
|
R7559:Foxp1
|
UTSW |
6 |
98,922,521 (GRCm39) |
missense |
unknown |
|
|
R7715:Foxp1
|
UTSW |
6 |
98,922,621 (GRCm39) |
missense |
unknown |
|
|
R8007:Foxp1
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R8099:Foxp1
|
UTSW |
6 |
98,922,510 (GRCm39) |
missense |
unknown |
|
|
R8317:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R8408:Foxp1
|
UTSW |
6 |
98,922,543 (GRCm39) |
missense |
unknown |
|
|
R8704:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R8705:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R9147:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9399:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9604:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
X0066:Foxp1
|
UTSW |
6 |
99,052,976 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Foxp1
|
UTSW |
6 |
98,955,122 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCATGCTGGATTCTTCCCAAC -3'
(R):5'- TCTCCAGACCTGTGTGATAATG -3'
Sequencing Primer
(F):5'- GAAACTTCTGGTCAAAGAGACTTTTC -3'
(R):5'- CTCCAGACCTGTGTGATAATGAAATC -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation