Incidental Mutation 'R9015:Tanc1'
| ID |
685885 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc1
|
| Ensembl Gene |
ENSMUSG00000035168 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| Synonyms |
1200003E16Rik |
| MMRRC Submission |
068845-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9015 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
59442386-59676493 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 59622224 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 448
(S448T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123345
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037526]
[ENSMUST00000112568]
[ENSMUST00000139863]
|
| AlphaFold |
Q0VGY8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037526
AA Change: S448T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000036003
Gene: ENSMUSG00000035168
AA Change: S448T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112568
AA Change: S441T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000108187
Gene: ENSMUSG00000035168
AA Change: S441T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
448 |
468 |
N/A |
INTRINSIC |
|
ANK
|
886 |
918 |
1.06e3 |
SMART |
|
ANK
|
922 |
953 |
2.43e3 |
SMART |
|
ANK
|
957 |
986 |
1.12e-3 |
SMART |
|
Blast:ANK
|
990 |
1021 |
7e-12 |
BLAST |
|
ANK
|
1030 |
1059 |
1.78e3 |
SMART |
|
ANK
|
1068 |
1097 |
2.34e-1 |
SMART |
|
ANK
|
1101 |
1130 |
3.71e-4 |
SMART |
|
ANK
|
1134 |
1163 |
1.51e-4 |
SMART |
|
ANK
|
1167 |
1196 |
4.89e-4 |
SMART |
|
ANK
|
1200 |
1229 |
3.01e-4 |
SMART |
|
ANK
|
1233 |
1262 |
1.99e2 |
SMART |
|
TPR
|
1279 |
1312 |
7.49e1 |
SMART |
|
TPR
|
1326 |
1359 |
2.35e-1 |
SMART |
|
TPR
|
1360 |
1393 |
6.29e-2 |
SMART |
|
low complexity region
|
1409 |
1425 |
N/A |
INTRINSIC |
|
low complexity region
|
1447 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1679 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139863
AA Change: S448T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000123345
Gene: ENSMUSG00000035168
AA Change: S448T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0846 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
100% (93/93) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam22 |
T |
C |
5: 8,136,688 (GRCm39) |
|
probably benign |
Het |
| Adamtsl1 |
A |
G |
4: 86,150,847 (GRCm39) |
D335G |
probably damaging |
Het |
| Adcy8 |
T |
C |
15: 64,597,206 (GRCm39) |
|
probably benign |
Het |
| Alas1 |
A |
T |
9: 106,113,670 (GRCm39) |
I525N |
probably benign |
Het |
| Aoah |
A |
T |
13: 21,184,197 (GRCm39) |
|
silent |
Het |
| Aox1 |
G |
A |
1: 58,382,851 (GRCm39) |
V1044M |
probably damaging |
Het |
| Apcdd1 |
A |
T |
18: 63,083,157 (GRCm39) |
Y329F |
possibly damaging |
Het |
| Arhgap10 |
A |
C |
8: 77,985,687 (GRCm39) |
C727G |
probably benign |
Het |
| Arid4a |
G |
A |
12: 71,122,168 (GRCm39) |
D528N |
possibly damaging |
Het |
| Atp8a1 |
A |
G |
5: 67,887,250 (GRCm39) |
V611A |
|
Het |
| BC004004 |
T |
C |
17: 29,517,637 (GRCm39) |
F284L |
probably damaging |
Het |
| Bean1 |
CT |
C |
8: 104,908,664 (GRCm39) |
|
probably null |
Het |
| Cep295 |
T |
C |
9: 15,244,264 (GRCm39) |
I1397M |
probably benign |
Het |
| Cep63 |
A |
G |
9: 102,496,111 (GRCm39) |
S99P |
probably damaging |
Het |
| Coq3 |
T |
A |
4: 21,899,107 (GRCm39) |
S147T |
probably benign |
Het |
| Crym |
A |
T |
7: 119,801,090 (GRCm39) |
S20T |
probably benign |
Het |
| Ctr9 |
T |
A |
7: 110,643,108 (GRCm39) |
N493K |
probably benign |
Het |
| Dchs2 |
A |
G |
3: 83,188,751 (GRCm39) |
I1372V |
possibly damaging |
Het |
| Ddi2 |
G |
A |
4: 141,412,747 (GRCm39) |
T55M |
probably benign |
Het |
| Dnah1 |
T |
C |
14: 30,986,316 (GRCm39) |
M3724V |
probably damaging |
Het |
| Dst |
A |
G |
1: 34,326,337 (GRCm39) |
I4690V |
probably benign |
Het |
| Ect2l |
T |
C |
10: 18,039,148 (GRCm39) |
T429A |
probably benign |
Het |
| Eif3c |
G |
T |
7: 126,155,538 (GRCm39) |
H577N |
probably damaging |
Het |
| Erg |
A |
G |
16: 95,162,126 (GRCm39) |
S334P |
possibly damaging |
Het |
| Faf2 |
A |
G |
13: 54,796,139 (GRCm39) |
S127G |
probably benign |
Het |
| Fbxl3 |
T |
A |
14: 103,329,790 (GRCm39) |
T141S |
possibly damaging |
Het |
| Fbxw4 |
T |
A |
19: 45,624,874 (GRCm39) |
M122L |
probably benign |
Het |
| Fgd4 |
T |
C |
16: 16,271,941 (GRCm39) |
M476V |
probably damaging |
Het |
| Flvcr2 |
A |
T |
12: 85,829,779 (GRCm39) |
I263F |
probably benign |
Het |
| Gadl1 |
A |
T |
9: 115,794,705 (GRCm39) |
R293S |
probably benign |
Het |
| Gm11983 |
G |
T |
11: 6,787,033 (GRCm39) |
F31L |
unknown |
Het |
| Gmnn |
A |
T |
13: 24,940,638 (GRCm39) |
N70K |
probably benign |
Het |
| Gpr3 |
A |
G |
4: 132,938,390 (GRCm39) |
V94A |
possibly damaging |
Het |
| Greb1l |
A |
G |
18: 10,541,675 (GRCm39) |
S1141G |
probably benign |
Het |
| Helz2 |
A |
T |
2: 180,870,792 (GRCm39) |
V2892E |
probably damaging |
Het |
| Hivep1 |
T |
A |
13: 42,311,849 (GRCm39) |
M1363K |
probably benign |
Het |
| Hk1 |
T |
A |
10: 62,128,118 (GRCm39) |
T336S |
possibly damaging |
Het |
| Hpgds |
A |
T |
6: 65,115,229 (GRCm39) |
I18N |
possibly damaging |
Het |
| Insrr |
T |
A |
3: 87,720,910 (GRCm39) |
L1056Q |
probably damaging |
Het |
| Ints10 |
A |
G |
8: 69,260,139 (GRCm39) |
M288V |
probably benign |
Het |
| Itgb6 |
T |
C |
2: 60,485,032 (GRCm39) |
D237G |
probably damaging |
Het |
| Kcnf1 |
A |
G |
12: 17,225,303 (GRCm39) |
I306T |
probably damaging |
Het |
| Kdm3b |
G |
A |
18: 34,963,212 (GRCm39) |
G1556D |
probably damaging |
Het |
| Kif5b |
A |
G |
18: 6,216,892 (GRCm39) |
L477P |
probably damaging |
Het |
| Klf5 |
T |
G |
14: 99,540,919 (GRCm39) |
*310G |
probably null |
Het |
| Lnx1 |
A |
G |
5: 74,780,783 (GRCm39) |
V246A |
probably benign |
Het |
| Ly75 |
C |
T |
2: 60,146,442 (GRCm39) |
E1279K |
probably benign |
Het |
| Lztr1 |
T |
A |
16: 17,337,305 (GRCm39) |
C233S |
probably benign |
Het |
| Mfsd6l |
T |
G |
11: 68,447,536 (GRCm39) |
I129S |
probably benign |
Het |
| Mrgprx2 |
T |
A |
7: 48,148,938 (GRCm39) |
|
probably benign |
Het |
| Ncapd2 |
A |
T |
6: 125,145,285 (GRCm39) |
|
probably benign |
Het |
| Or10ag53 |
T |
A |
2: 87,082,546 (GRCm39) |
Y88* |
probably null |
Het |
| Or12e9 |
T |
A |
2: 87,202,485 (GRCm39) |
M203K |
possibly damaging |
Het |
| Or2a25 |
G |
T |
6: 42,888,825 (GRCm39) |
V123L |
possibly damaging |
Het |
| Or8g30 |
A |
C |
9: 39,230,019 (GRCm39) |
V297G |
probably damaging |
Het |
| Pde6a |
A |
G |
18: 61,397,047 (GRCm39) |
H631R |
probably damaging |
Het |
| Pfkl |
C |
T |
10: 77,824,794 (GRCm39) |
G665D |
probably damaging |
Het |
| Pik3ap1 |
T |
A |
19: 41,270,430 (GRCm39) |
E753V |
probably damaging |
Het |
| Pik3cd |
G |
T |
4: 149,740,055 (GRCm39) |
R502S |
probably benign |
Het |
| Piwil2 |
T |
A |
14: 70,627,984 (GRCm39) |
I762L |
probably benign |
Het |
| Pkd1 |
T |
A |
17: 24,784,636 (GRCm39) |
L394* |
probably null |
Het |
| Plekhb2 |
A |
G |
1: 34,916,046 (GRCm39) |
D195G |
probably benign |
Het |
| Plppr5 |
T |
C |
3: 117,456,103 (GRCm39) |
M208T |
probably damaging |
Het |
| Polr2i |
G |
A |
7: 29,932,513 (GRCm39) |
V115I |
unknown |
Het |
| Prkacb |
T |
C |
3: 146,456,239 (GRCm39) |
S187G |
probably null |
Het |
| Prkag3 |
G |
T |
1: 74,780,353 (GRCm39) |
H437Q |
probably benign |
Het |
| Prlr |
T |
A |
15: 10,319,352 (GRCm39) |
Y94N |
probably damaging |
Het |
| Prmt6 |
T |
C |
3: 110,157,214 (GRCm39) |
I358M |
probably benign |
Het |
| Psd4 |
A |
G |
2: 24,287,492 (GRCm39) |
R475G |
|
Het |
| Rad51b |
G |
A |
12: 79,347,417 (GRCm39) |
C27Y |
probably damaging |
Het |
| Scfd2 |
A |
G |
5: 74,691,625 (GRCm39) |
L219P |
probably damaging |
Het |
| Scn5a |
G |
A |
9: 119,381,142 (GRCm39) |
|
probably benign |
Het |
| Sec24d |
T |
C |
3: 123,121,287 (GRCm39) |
V391A |
probably benign |
Het |
| Selenbp2 |
T |
A |
3: 94,607,332 (GRCm39) |
L251Q |
probably damaging |
Het |
| Sh3rf1 |
T |
C |
8: 61,827,202 (GRCm39) |
V652A |
probably benign |
Het |
| Slc11a2 |
A |
G |
15: 100,301,186 (GRCm39) |
V289A |
probably benign |
Het |
| Smim29 |
T |
C |
17: 27,783,223 (GRCm39) |
D48G |
probably benign |
Het |
| Sox8 |
T |
A |
17: 25,789,135 (GRCm39) |
Y121F |
probably damaging |
Het |
| Taar7a |
A |
T |
10: 23,868,733 (GRCm39) |
I216N |
probably damaging |
Het |
| Tas2r119 |
G |
A |
15: 32,178,226 (GRCm39) |
G264D |
probably damaging |
Het |
| Trav7-6 |
A |
G |
14: 53,954,604 (GRCm39) |
K65E |
probably benign |
Het |
| Trim17 |
A |
G |
11: 58,856,057 (GRCm39) |
E38G |
probably damaging |
Het |
| Trub2 |
A |
T |
2: 29,668,276 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,571,964 (GRCm39) |
M26310L |
probably damaging |
Het |
| Unc13c |
T |
G |
9: 73,453,322 (GRCm39) |
I1823L |
probably benign |
Het |
| Vav2 |
C |
A |
2: 27,160,151 (GRCm39) |
E728* |
probably null |
Het |
| Virma |
A |
G |
4: 11,540,494 (GRCm39) |
D1465G |
probably benign |
Het |
| Vmn2r72 |
T |
G |
7: 85,398,388 (GRCm39) |
M531L |
probably benign |
Het |
| Vwa3b |
G |
A |
1: 37,203,597 (GRCm39) |
V59I |
possibly damaging |
Het |
| Xrcc1 |
G |
A |
7: 24,271,642 (GRCm39) |
E542K |
probably benign |
Het |
| Zdhhc6 |
T |
G |
19: 55,287,318 (GRCm39) |
T381P |
probably benign |
Het |
| Zdhhc8 |
T |
C |
16: 18,041,141 (GRCm39) |
S740G |
probably damaging |
Het |
| Zfp106 |
T |
C |
2: 120,364,019 (GRCm39) |
K819R |
probably damaging |
Het |
|
| Other mutations in Tanc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Tanc1
|
APN |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL00484:Tanc1
|
APN |
2 |
59,623,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00688:Tanc1
|
APN |
2 |
59,645,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00765:Tanc1
|
APN |
2 |
59,636,645 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01576:Tanc1
|
APN |
2 |
59,628,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01590:Tanc1
|
APN |
2 |
59,615,817 (GRCm39) |
missense |
probably benign |
|
|
IGL02016:Tanc1
|
APN |
2 |
59,673,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02373:Tanc1
|
APN |
2 |
59,626,372 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02539:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02541:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Tanc1
|
APN |
2 |
59,554,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL02626:Tanc1
|
APN |
2 |
59,630,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02669:Tanc1
|
APN |
2 |
59,630,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Tanc1
|
APN |
2 |
59,623,431 (GRCm39) |
splice site |
probably benign |
|
|
Oreja
|
UTSW |
2 |
59,622,148 (GRCm39) |
synonymous |
silent |
|
|
R0178:Tanc1
|
UTSW |
2 |
59,665,791 (GRCm39) |
nonsense |
probably null |
|
|
R0347:Tanc1
|
UTSW |
2 |
59,673,335 (GRCm39) |
missense |
probably benign |
|
|
R0570:Tanc1
|
UTSW |
2 |
59,626,382 (GRCm39) |
splice site |
probably benign |
|
|
R0660:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0664:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0898:Tanc1
|
UTSW |
2 |
59,621,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1333:Tanc1
|
UTSW |
2 |
59,673,835 (GRCm39) |
missense |
probably benign |
|
|
R1575:Tanc1
|
UTSW |
2 |
59,621,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1608:Tanc1
|
UTSW |
2 |
59,628,038 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1616:Tanc1
|
UTSW |
2 |
59,615,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1703:Tanc1
|
UTSW |
2 |
59,673,365 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1727:Tanc1
|
UTSW |
2 |
59,621,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Tanc1
|
UTSW |
2 |
59,630,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1812:Tanc1
|
UTSW |
2 |
59,622,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1925:Tanc1
|
UTSW |
2 |
59,555,095 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1951:Tanc1
|
UTSW |
2 |
59,622,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Tanc1
|
UTSW |
2 |
59,674,177 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2228:Tanc1
|
UTSW |
2 |
59,555,068 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2267:Tanc1
|
UTSW |
2 |
59,667,563 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4191:Tanc1
|
UTSW |
2 |
59,669,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4476:Tanc1
|
UTSW |
2 |
59,672,340 (GRCm39) |
splice site |
probably null |
|
|
R4632:Tanc1
|
UTSW |
2 |
59,626,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Tanc1
|
UTSW |
2 |
59,529,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4982:Tanc1
|
UTSW |
2 |
59,630,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5338:Tanc1
|
UTSW |
2 |
59,626,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5657:Tanc1
|
UTSW |
2 |
59,665,051 (GRCm39) |
splice site |
probably null |
|
|
R5672:Tanc1
|
UTSW |
2 |
59,602,697 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5703:Tanc1
|
UTSW |
2 |
59,626,341 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5707:Tanc1
|
UTSW |
2 |
59,588,874 (GRCm39) |
missense |
probably benign |
|
|
R5778:Tanc1
|
UTSW |
2 |
59,529,691 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5795:Tanc1
|
UTSW |
2 |
59,637,926 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5831:Tanc1
|
UTSW |
2 |
59,615,685 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5849:Tanc1
|
UTSW |
2 |
59,630,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5912:Tanc1
|
UTSW |
2 |
59,622,030 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5944:Tanc1
|
UTSW |
2 |
59,667,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6057:Tanc1
|
UTSW |
2 |
59,647,837 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6142:Tanc1
|
UTSW |
2 |
59,663,566 (GRCm39) |
nonsense |
probably null |
|
|
R6179:Tanc1
|
UTSW |
2 |
59,673,320 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6185:Tanc1
|
UTSW |
2 |
59,621,929 (GRCm39) |
splice site |
probably null |
|
|
R6192:Tanc1
|
UTSW |
2 |
59,669,305 (GRCm39) |
splice site |
probably null |
|
|
R6196:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6197:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6230:Tanc1
|
UTSW |
2 |
59,672,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6275:Tanc1
|
UTSW |
2 |
59,673,854 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6415:Tanc1
|
UTSW |
2 |
59,667,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6480:Tanc1
|
UTSW |
2 |
59,637,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6578:Tanc1
|
UTSW |
2 |
59,626,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Tanc1
|
UTSW |
2 |
59,622,150 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7006:Tanc1
|
UTSW |
2 |
59,626,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Tanc1
|
UTSW |
2 |
59,627,953 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7381:Tanc1
|
UTSW |
2 |
59,615,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Tanc1
|
UTSW |
2 |
59,636,688 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8392:Tanc1
|
UTSW |
2 |
59,636,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8692:Tanc1
|
UTSW |
2 |
59,673,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8730:Tanc1
|
UTSW |
2 |
59,601,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8731:Tanc1
|
UTSW |
2 |
59,673,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8813:Tanc1
|
UTSW |
2 |
59,630,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8815:Tanc1
|
UTSW |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8933:Tanc1
|
UTSW |
2 |
59,615,800 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9042:Tanc1
|
UTSW |
2 |
59,673,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9154:Tanc1
|
UTSW |
2 |
59,630,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9269:Tanc1
|
UTSW |
2 |
59,630,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Tanc1
|
UTSW |
2 |
59,630,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9380:Tanc1
|
UTSW |
2 |
59,665,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tanc1
|
UTSW |
2 |
59,637,933 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9428:Tanc1
|
UTSW |
2 |
59,601,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Tanc1
|
UTSW |
2 |
59,626,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF028:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
RF049:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Tanc1
|
UTSW |
2 |
59,674,324 (GRCm39) |
nonsense |
probably null |
|
|
X0064:Tanc1
|
UTSW |
2 |
59,674,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tanc1
|
UTSW |
2 |
59,602,873 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,622,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,621,231 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGCTCTTTCACCAGATAGAGG -3'
(R):5'- AACAATGTGAGACCCTCTCTC -3'
Sequencing Primer
(F):5'- GGCTCTTTCACCAGATAGAGGAAAAC -3'
(R):5'- TCTCCCTCTCCCATCAGAAAAAGTG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation