Incidental Mutation 'R9043:Slc4a7'
| ID |
687873 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Slc4a7
|
| Ensembl Gene |
ENSMUSG00000021733 |
| Gene Name |
solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| Synonyms |
NBC3, NBCn1, E430014N10Rik |
| MMRRC Submission |
068870-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.925)
|
| Stock # |
R9043 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
7669819-7766808 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 14775048 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 826
(L826P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000058313
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057015]
[ENSMUST00000223607]
[ENSMUST00000223695]
[ENSMUST00000223740]
[ENSMUST00000223761]
[ENSMUST00000223981]
[ENSMUST00000224049]
[ENSMUST00000224222]
[ENSMUST00000224333]
[ENSMUST00000224672]
[ENSMUST00000224752]
[ENSMUST00000225175]
[ENSMUST00000225232]
[ENSMUST00000225238]
[ENSMUST00000225630]
[ENSMUST00000225979]
[ENSMUST00000226079]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000057015
AA Change: L826P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000058313
Gene: ENSMUSG00000021733
AA Change: L826P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
57 |
89 |
N/A |
INTRINSIC |
|
Pfam:Band_3_cyto
|
146 |
413 |
1.4e-110 |
PFAM |
|
Pfam:HCO3_cotransp
|
456 |
969 |
1.6e-242 |
PFAM |
|
transmembrane domain
|
977 |
999 |
N/A |
INTRINSIC |
|
coiled coil region
|
1021 |
1050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000223607
AA Change: L938P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000223695
AA Change: L839P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000223740
AA Change: L832P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000223761
AA Change: L949P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000223981
AA Change: L951P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000224049
AA Change: L819P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000224222
AA Change: L938P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000224333
AA Change: L957P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000224672
AA Change: L942P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000224752
AA Change: L943P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225175
AA Change: L936P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225232
AA Change: L813P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225238
AA Change: L846P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225630
AA Change: L813P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225979
AA Change: L833P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000226079
AA Change: L826P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.0%
|
| Validation Efficiency |
99% (87/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
PHENOTYPE: Mice homozygous for a disruption at this locus display defects of the auditory and visual systems similar to those observed in patients with Ushers syndrome. Mice homozygous for a gene trap allele exhibit disruption in sodium/bicarbonate function that impacts vasodilation and hypertension. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933402J07Rik |
T |
A |
8: 88,309,238 (GRCm39) |
S134T |
possibly damaging |
Het |
| Aadacl4 |
T |
A |
4: 144,349,790 (GRCm39) |
L349Q |
probably damaging |
Het |
| Ankrd29 |
T |
C |
18: 12,428,970 (GRCm39) |
N33S |
probably damaging |
Het |
| Arid3b |
T |
C |
9: 57,699,900 (GRCm39) |
S536G |
possibly damaging |
Het |
| Art5 |
A |
C |
7: 101,748,699 (GRCm39) |
M1R |
probably null |
Het |
| Arvcf |
T |
A |
16: 18,218,452 (GRCm39) |
C545S |
probably damaging |
Het |
| Atpsckmt |
A |
G |
15: 31,617,101 (GRCm39) |
T189A |
probably benign |
Het |
| Axin2 |
T |
A |
11: 108,833,794 (GRCm39) |
N580K |
probably benign |
Het |
| Cdh23 |
T |
G |
10: 60,151,478 (GRCm39) |
D2469A |
probably benign |
Het |
| Cep350 |
T |
A |
1: 155,773,228 (GRCm39) |
T1781S |
probably damaging |
Het |
| Cfap65 |
T |
A |
1: 74,943,847 (GRCm39) |
T1555S |
possibly damaging |
Het |
| Chga |
G |
A |
12: 102,529,054 (GRCm39) |
E344K |
possibly damaging |
Het |
| Ckap2l |
A |
T |
2: 129,126,892 (GRCm39) |
L429M |
probably damaging |
Het |
| Cpne7 |
C |
T |
8: 123,856,951 (GRCm39) |
P402L |
probably damaging |
Het |
| Cyp2g1 |
A |
G |
7: 26,509,256 (GRCm39) |
N110S |
probably benign |
Het |
| Cyp3a11 |
T |
C |
5: 145,805,995 (GRCm39) |
D124G |
probably benign |
Het |
| Dgkq |
A |
T |
5: 108,801,061 (GRCm39) |
V527D |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 119,551,272 (GRCm39) |
I37V |
probably benign |
Het |
| Dnah9 |
T |
A |
11: 65,845,680 (GRCm39) |
E3068V |
|
Het |
| Dusp23 |
T |
C |
1: 172,460,184 (GRCm39) |
E89G |
probably null |
Het |
| Fam187a |
A |
G |
11: 102,776,685 (GRCm39) |
Y163C |
possibly damaging |
Het |
| Gabrg2 |
T |
A |
11: 41,865,662 (GRCm39) |
I106F |
probably damaging |
Het |
| Gpc2 |
A |
G |
5: 138,277,193 (GRCm39) |
I78T |
probably benign |
Het |
| Gpr149 |
A |
C |
3: 62,511,360 (GRCm39) |
L213R |
probably damaging |
Het |
| Grm1 |
A |
T |
10: 10,565,056 (GRCm39) |
L1084* |
probably null |
Het |
| Gypa |
A |
G |
8: 81,222,946 (GRCm39) |
T17A |
unknown |
Het |
| Gys2 |
A |
T |
6: 142,376,059 (GRCm39) |
F534L |
probably damaging |
Het |
| Iqce |
A |
T |
5: 140,651,810 (GRCm39) |
M721K |
probably benign |
Het |
| Klrc2 |
T |
A |
6: 129,635,741 (GRCm39) |
Y129F |
probably damaging |
Het |
| Krt14 |
T |
C |
11: 100,095,464 (GRCm39) |
S314G |
possibly damaging |
Het |
| L3mbtl3 |
T |
C |
10: 26,156,152 (GRCm39) |
Q685R |
unknown |
Het |
| Lamb3 |
A |
T |
1: 193,007,919 (GRCm39) |
K206* |
probably null |
Het |
| Lgr5 |
A |
G |
10: 115,314,343 (GRCm39) |
I198T |
probably damaging |
Het |
| Mapk10 |
A |
T |
5: 103,074,025 (GRCm39) |
|
probably benign |
Het |
| Mcm6 |
C |
T |
1: 128,271,231 (GRCm39) |
D463N |
probably damaging |
Het |
| Med15 |
A |
T |
16: 17,470,582 (GRCm39) |
W742R |
probably benign |
Het |
| Meis1 |
T |
A |
11: 18,831,916 (GRCm39) |
Q374L |
possibly damaging |
Het |
| Nrxn3 |
T |
C |
12: 89,227,252 (GRCm39) |
C296R |
probably damaging |
Het |
| Ntaq1 |
A |
G |
15: 58,014,004 (GRCm39) |
Y67C |
possibly damaging |
Het |
| Oaf |
C |
T |
9: 43,135,308 (GRCm39) |
A157T |
probably damaging |
Het |
| Oca2 |
T |
A |
7: 55,927,189 (GRCm39) |
|
probably null |
Het |
| Or5b110-ps1 |
A |
T |
19: 13,260,074 (GRCm39) |
M116K |
probably damaging |
Het |
| Or5b12 |
T |
A |
19: 12,897,667 (GRCm39) |
E2V |
probably benign |
Het |
| Or5d36 |
T |
A |
2: 87,900,983 (GRCm39) |
T248S |
possibly damaging |
Het |
| Or9k2b |
A |
T |
10: 130,016,154 (GRCm39) |
H198Q |
probably benign |
Het |
| Pacs1 |
A |
G |
19: 5,188,964 (GRCm39) |
I806T |
probably benign |
Het |
| Pax2 |
T |
A |
19: 44,804,499 (GRCm39) |
S257T |
probably benign |
Het |
| Pbxip1 |
A |
T |
3: 89,350,794 (GRCm39) |
T72S |
probably benign |
Het |
| Pcdhb14 |
T |
C |
18: 37,581,851 (GRCm39) |
I319T |
probably damaging |
Het |
| Pcdhga2 |
C |
A |
18: 37,802,963 (GRCm39) |
A269E |
possibly damaging |
Het |
| Pdzph1 |
A |
C |
17: 59,280,535 (GRCm39) |
N582K |
probably benign |
Het |
| Plk2 |
A |
T |
13: 110,533,194 (GRCm39) |
I186F |
probably damaging |
Het |
| Pzp |
A |
T |
6: 128,471,742 (GRCm39) |
C895S |
probably damaging |
Het |
| Rasa2 |
A |
T |
9: 96,484,770 (GRCm39) |
V148D |
probably damaging |
Het |
| Rgsl1 |
A |
T |
1: 153,717,567 (GRCm39) |
I14N |
possibly damaging |
Het |
| Rhox3c |
C |
T |
X: 36,651,303 (GRCm39) |
|
probably benign |
Het |
| Rnf213 |
A |
G |
11: 119,349,739 (GRCm39) |
R3867G |
|
Het |
| Rpap3 |
A |
G |
15: 97,584,443 (GRCm39) |
Y334H |
possibly damaging |
Het |
| Scara3 |
A |
C |
14: 66,169,070 (GRCm39) |
N182K |
probably damaging |
Het |
| Sh3bp1 |
A |
G |
15: 78,791,449 (GRCm39) |
E412G |
possibly damaging |
Het |
| Sh3tc2 |
T |
A |
18: 62,122,961 (GRCm39) |
I574N |
possibly damaging |
Het |
| Slc16a11 |
T |
C |
11: 70,106,520 (GRCm39) |
Y253H |
probably damaging |
Het |
| Slc38a4 |
A |
T |
15: 96,906,805 (GRCm39) |
V311E |
possibly damaging |
Het |
| Spag9 |
T |
G |
11: 93,951,085 (GRCm39) |
V83G |
|
Het |
| Sspo |
T |
G |
6: 48,470,214 (GRCm39) |
V4560G |
probably benign |
Het |
| Stxbp2 |
T |
A |
8: 3,684,478 (GRCm39) |
F144I |
|
Het |
| Tafa2 |
T |
C |
10: 123,540,294 (GRCm39) |
V50A |
probably damaging |
Het |
| Tdh |
T |
C |
14: 63,730,278 (GRCm39) |
I334V |
probably benign |
Het |
| Tesk2 |
C |
A |
4: 116,660,148 (GRCm39) |
S451Y |
probably benign |
Het |
| Tjp1 |
A |
T |
7: 64,962,679 (GRCm39) |
V1166E |
probably benign |
Het |
| Tmeff2 |
G |
A |
1: 51,018,779 (GRCm39) |
V254M |
unknown |
Het |
| Tmem126a |
A |
G |
7: 90,100,749 (GRCm39) |
|
probably null |
Het |
| Togaram2 |
C |
G |
17: 71,993,699 (GRCm39) |
P2A |
probably benign |
Het |
| Trappc14 |
G |
A |
5: 138,259,889 (GRCm39) |
T389I |
possibly damaging |
Het |
| Tssk4 |
C |
T |
14: 55,889,211 (GRCm39) |
R246W |
probably damaging |
Het |
| Tubal3 |
C |
T |
13: 3,982,708 (GRCm39) |
R163* |
probably null |
Het |
| Usp48 |
G |
A |
4: 137,340,996 (GRCm39) |
G332E |
probably benign |
Het |
| Vezt |
T |
C |
10: 93,820,027 (GRCm39) |
N446S |
probably damaging |
Het |
| Vim |
A |
T |
2: 13,579,249 (GRCm39) |
T3S |
unknown |
Het |
| Vmn2r45 |
A |
G |
7: 8,474,904 (GRCm39) |
L708P |
possibly damaging |
Het |
| Yes1 |
A |
G |
5: 32,810,312 (GRCm39) |
Y157C |
probably damaging |
Het |
| Zfp358 |
A |
G |
8: 3,545,810 (GRCm39) |
T131A |
probably benign |
Het |
| Zfp426 |
C |
T |
9: 20,386,308 (GRCm39) |
V58M |
probably damaging |
Het |
| Zfp692 |
T |
C |
11: 58,198,550 (GRCm39) |
S47P |
probably damaging |
Het |
| Zfp719 |
A |
T |
7: 43,239,605 (GRCm39) |
T398S |
possibly damaging |
Het |
|
| Other mutations in Slc4a7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00974:Slc4a7
|
APN |
14 |
14,760,292 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL01468:Slc4a7
|
APN |
14 |
14,737,480 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01863:Slc4a7
|
APN |
14 |
14,762,430 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL03122:Slc4a7
|
APN |
14 |
14,782,040 (GRCm38) |
splice site |
probably benign |
|
|
R0020:Slc4a7
|
UTSW |
14 |
14,796,108 (GRCm38) |
missense |
probably benign |
|
|
R0403:Slc4a7
|
UTSW |
14 |
14,766,808 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0410:Slc4a7
|
UTSW |
14 |
14,738,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0624:Slc4a7
|
UTSW |
14 |
14,794,059 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0631:Slc4a7
|
UTSW |
14 |
14,757,382 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1128:Slc4a7
|
UTSW |
14 |
14,733,832 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1556:Slc4a7
|
UTSW |
14 |
14,778,872 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1672:Slc4a7
|
UTSW |
14 |
14,760,247 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1711:Slc4a7
|
UTSW |
14 |
14,765,709 (GRCm38) |
missense |
probably benign |
0.45 |
|
R1870:Slc4a7
|
UTSW |
14 |
14,737,509 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1939:Slc4a7
|
UTSW |
14 |
14,748,581 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2012:Slc4a7
|
UTSW |
14 |
14,733,727 (GRCm38) |
nonsense |
probably null |
|
|
R2042:Slc4a7
|
UTSW |
14 |
14,737,386 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2064:Slc4a7
|
UTSW |
14 |
14,733,773 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2404:Slc4a7
|
UTSW |
14 |
14,733,733 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2880:Slc4a7
|
UTSW |
14 |
14,773,277 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3729:Slc4a7
|
UTSW |
14 |
14,729,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4368:Slc4a7
|
UTSW |
14 |
14,733,775 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4395:Slc4a7
|
UTSW |
14 |
14,765,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4432:Slc4a7
|
UTSW |
14 |
14,757,323 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4592:Slc4a7
|
UTSW |
14 |
14,778,850 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4705:Slc4a7
|
UTSW |
14 |
14,733,856 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4743:Slc4a7
|
UTSW |
14 |
14,796,073 (GRCm38) |
splice site |
probably null |
|
|
R4765:Slc4a7
|
UTSW |
14 |
14,762,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4831:Slc4a7
|
UTSW |
14 |
14,772,699 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4845:Slc4a7
|
UTSW |
14 |
14,733,803 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4880:Slc4a7
|
UTSW |
14 |
14,757,342 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4948:Slc4a7
|
UTSW |
14 |
14,771,283 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R5348:Slc4a7
|
UTSW |
14 |
14,786,310 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5385:Slc4a7
|
UTSW |
14 |
14,773,345 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5418:Slc4a7
|
UTSW |
14 |
14,760,280 (GRCm38) |
missense |
probably benign |
0.25 |
|
R5480:Slc4a7
|
UTSW |
14 |
14,782,138 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5842:Slc4a7
|
UTSW |
14 |
14,778,866 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5919:Slc4a7
|
UTSW |
14 |
14,791,092 (GRCm38) |
missense |
probably benign |
|
|
R6063:Slc4a7
|
UTSW |
14 |
14,793,964 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R6065:Slc4a7
|
UTSW |
14 |
14,739,836 (GRCm38) |
missense |
probably benign |
0.29 |
|
R6549:Slc4a7
|
UTSW |
14 |
14,748,564 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6845:Slc4a7
|
UTSW |
14 |
14,775,000 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6870:Slc4a7
|
UTSW |
14 |
14,733,846 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6881:Slc4a7
|
UTSW |
14 |
14,737,452 (GRCm38) |
missense |
probably benign |
0.43 |
|
R6962:Slc4a7
|
UTSW |
14 |
14,746,021 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7099:Slc4a7
|
UTSW |
14 |
14,733,750 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7180:Slc4a7
|
UTSW |
14 |
14,765,580 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7346:Slc4a7
|
UTSW |
14 |
14,775,000 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7378:Slc4a7
|
UTSW |
14 |
14,757,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7646:Slc4a7
|
UTSW |
14 |
14,773,348 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7647:Slc4a7
|
UTSW |
14 |
14,773,348 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7648:Slc4a7
|
UTSW |
14 |
14,773,348 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7650:Slc4a7
|
UTSW |
14 |
14,773,348 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7857:Slc4a7
|
UTSW |
14 |
14,772,624 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7892:Slc4a7
|
UTSW |
14 |
14,773,348 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8124:Slc4a7
|
UTSW |
14 |
14,729,211 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8225:Slc4a7
|
UTSW |
14 |
14,738,224 (GRCm38) |
nonsense |
probably null |
|
|
R8354:Slc4a7
|
UTSW |
14 |
14,786,313 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8998:Slc4a7
|
UTSW |
14 |
14,775,346 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9016:Slc4a7
|
UTSW |
14 |
14,773,241 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9139:Slc4a7
|
UTSW |
14 |
14,796,115 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9342:Slc4a7
|
UTSW |
14 |
14,772,541 (GRCm38) |
nonsense |
probably null |
|
|
R9383:Slc4a7
|
UTSW |
14 |
14,766,803 (GRCm38) |
nonsense |
probably null |
|
|
R9568:Slc4a7
|
UTSW |
14 |
14,796,073 (GRCm38) |
splice site |
probably null |
|
|
R9798:Slc4a7
|
UTSW |
14 |
14,782,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0067:Slc4a7
|
UTSW |
14 |
14,771,276 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAATAGATCCACTTATGTGCTGTG -3'
(R):5'- ACGGCAAGCCCATGATAGAG -3'
Sequencing Primer
(F):5'- ACTTATGTGCTGTGGAAATTTGGTAC -3'
(R):5'- GCCCATGATAGAGCAGACTC -3'
|
| Posted On |
2021-11-19 |
Incidental Mutation