Incidental Mutation 'R9047:Tnrc6a'
| ID |
688119 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6a
|
| Ensembl Gene |
ENSMUSG00000052707 |
| Gene Name |
trinucleotide repeat containing 6a |
| Synonyms |
3110054G10Rik, 2010321I05Rik, Tnrc6, CAGH26, D130023A07Rik |
| MMRRC Submission |
068873-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.850)
|
| Stock # |
R9047 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
122723108-122794519 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 122778946 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Serine
at position 1219
(L1219S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091595
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094053]
[ENSMUST00000205514]
[ENSMUST00000206014]
[ENSMUST00000206888]
|
| AlphaFold |
Q3UHK8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000094053
AA Change: L1219S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000091595
Gene: ENSMUSG00000052707
AA Change: L1219S
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
568 |
590 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
690 |
853 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
858 |
871 |
N/A |
INTRINSIC |
|
Pfam:Ago_hook
|
1028 |
1190 |
1.2e-29 |
PFAM |
|
low complexity region
|
1284 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1301 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1392 |
N/A |
INTRINSIC |
|
Pfam:TNRC6-PABC_bdg
|
1439 |
1714 |
1.5e-126 |
PFAM |
|
RRM
|
1717 |
1784 |
4.95e-2 |
SMART |
|
low complexity region
|
1808 |
1820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205514
|
| Predicted Effect |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000206014
AA Change: L82S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206888
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.9%
- 20x: 99.7%
|
| Validation Efficiency |
100% (76/76) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit partial embryonic lethality during organogenesis associated with impaired hematopoiesis. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(21) : Gene trapped(21) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410004B18Rik |
T |
A |
3: 145,644,848 (GRCm39) |
S156T |
probably damaging |
Het |
| 4930522L14Rik |
A |
G |
5: 109,885,420 (GRCm39) |
L146P |
|
Het |
| Adra1a |
T |
A |
14: 66,875,634 (GRCm39) |
M203K |
probably damaging |
Het |
| Adtrp |
G |
A |
13: 41,969,636 (GRCm39) |
T89I |
possibly damaging |
Het |
| Akt3 |
G |
T |
1: 176,886,955 (GRCm39) |
T298K |
probably damaging |
Het |
| Aldh4a1 |
G |
T |
4: 139,350,511 (GRCm39) |
|
probably benign |
Het |
| Aplf |
T |
C |
6: 87,640,779 (GRCm39) |
T77A |
possibly damaging |
Het |
| Arid4b |
T |
A |
13: 14,355,815 (GRCm39) |
W618R |
probably damaging |
Het |
| Asxl3 |
C |
A |
18: 22,585,465 (GRCm39) |
P130Q |
probably damaging |
Het |
| Asxl3 |
A |
G |
18: 22,585,471 (GRCm39) |
K132R |
probably damaging |
Het |
| Atp11a |
T |
C |
8: 12,878,483 (GRCm39) |
M353T |
probably damaging |
Het |
| Atp11b |
A |
G |
3: 35,861,038 (GRCm39) |
D375G |
probably damaging |
Het |
| Cage1 |
C |
T |
13: 38,201,338 (GRCm39) |
A656T |
possibly damaging |
Het |
| Casz1 |
C |
T |
4: 149,023,497 (GRCm39) |
P801S |
probably damaging |
Het |
| Cdc14b |
A |
T |
13: 64,368,758 (GRCm39) |
|
probably benign |
Het |
| Cdin1 |
A |
G |
2: 115,607,504 (GRCm39) |
T286A |
probably benign |
Het |
| Cox6b2 |
A |
G |
7: 4,755,086 (GRCm39) |
F63L |
probably benign |
Het |
| Cramp1 |
A |
C |
17: 25,198,603 (GRCm39) |
V773G |
possibly damaging |
Het |
| Cul7 |
A |
G |
17: 46,965,448 (GRCm39) |
E542G |
probably benign |
Het |
| Cyp2c55 |
T |
C |
19: 39,019,790 (GRCm39) |
Y243H |
possibly damaging |
Het |
| Dnah9 |
C |
A |
11: 65,962,925 (GRCm39) |
D1797Y |
possibly damaging |
Het |
| Dpep2 |
C |
A |
8: 106,715,944 (GRCm39) |
A298S |
|
Het |
| Dvl3 |
G |
A |
16: 20,342,826 (GRCm39) |
|
probably null |
Het |
| Dynlt2a3 |
A |
G |
17: 15,187,942 (GRCm39) |
Y111H |
probably damaging |
Het |
| Enpp3 |
T |
C |
10: 24,674,172 (GRCm39) |
D376G |
possibly damaging |
Het |
| Ffar4 |
T |
C |
19: 38,102,232 (GRCm39) |
I289T |
possibly damaging |
Het |
| Gm5565 |
T |
C |
5: 146,094,849 (GRCm39) |
Y299C |
probably damaging |
Het |
| Gm57858 |
A |
G |
3: 36,087,033 (GRCm39) |
I187T |
probably benign |
Het |
| Gpat3 |
A |
T |
5: 100,994,788 (GRCm39) |
M39L |
probably benign |
Het |
| Gpr153 |
T |
C |
4: 152,364,664 (GRCm39) |
L240P |
probably damaging |
Het |
| Gpr182 |
T |
C |
10: 127,586,517 (GRCm39) |
I145V |
probably benign |
Het |
| H2-Q4 |
A |
T |
17: 35,598,969 (GRCm39) |
T80S |
possibly damaging |
Het |
| Hnf1a |
T |
A |
5: 115,088,882 (GRCm39) |
T545S |
probably benign |
Het |
| Kif5b |
A |
C |
18: 6,208,261 (GRCm39) |
F946V |
probably benign |
Het |
| Krtap16-1 |
C |
T |
11: 99,877,167 (GRCm39) |
C79Y |
probably damaging |
Het |
| Lama2 |
A |
G |
10: 26,882,697 (GRCm39) |
V2622A |
possibly damaging |
Het |
| Lrrc37a |
T |
A |
11: 103,391,375 (GRCm39) |
Q1350L |
probably damaging |
Het |
| Map2k2 |
G |
A |
10: 80,955,498 (GRCm39) |
V294I |
probably benign |
Het |
| Meak7 |
T |
C |
8: 120,489,050 (GRCm39) |
N411S |
probably benign |
Het |
| Mtus1 |
G |
A |
8: 41,536,760 (GRCm39) |
H319Y |
possibly damaging |
Het |
| Ncdn |
T |
C |
4: 126,644,621 (GRCm39) |
D67G |
possibly damaging |
Het |
| Ngef |
G |
A |
1: 87,431,010 (GRCm39) |
P269L |
probably damaging |
Het |
| Nlrp9b |
A |
G |
7: 19,757,401 (GRCm39) |
I213V |
possibly damaging |
Het |
| Nyap2 |
G |
A |
1: 81,275,803 (GRCm39) |
R649H |
possibly damaging |
Het |
| Or14a258 |
A |
G |
7: 86,035,248 (GRCm39) |
S207P |
probably benign |
Het |
| Or4a67 |
C |
A |
2: 88,598,299 (GRCm39) |
R120L |
probably damaging |
Het |
| Or5d20-ps1 |
T |
G |
2: 87,931,416 (GRCm39) |
D305A |
unknown |
Het |
| Pi4kb |
T |
A |
3: 94,900,428 (GRCm39) |
L354Q |
probably damaging |
Het |
| Plekhh2 |
T |
C |
17: 84,898,190 (GRCm39) |
S944P |
probably damaging |
Het |
| Podn |
C |
T |
4: 107,878,743 (GRCm39) |
V375M |
probably damaging |
Het |
| Pramel12 |
C |
A |
4: 143,145,673 (GRCm39) |
Q381K |
possibly damaging |
Het |
| Psmb2 |
T |
A |
4: 126,599,895 (GRCm39) |
H110Q |
probably benign |
Het |
| Rasip1 |
A |
G |
7: 45,282,066 (GRCm39) |
E523G |
possibly damaging |
Het |
| Ripor1 |
T |
G |
8: 106,342,783 (GRCm39) |
C219G |
probably damaging |
Het |
| Rps6ka2 |
G |
C |
17: 7,567,678 (GRCm39) |
V714L |
probably damaging |
Het |
| Sass6 |
G |
T |
3: 116,407,647 (GRCm39) |
L254F |
probably damaging |
Het |
| Scarf2 |
G |
A |
16: 17,624,270 (GRCm39) |
G525E |
probably damaging |
Het |
| Sh3d21 |
T |
A |
4: 126,046,131 (GRCm39) |
|
probably benign |
Het |
| Sh3tc1 |
C |
A |
5: 35,863,827 (GRCm39) |
A787S |
probably benign |
Het |
| Skint5 |
T |
A |
4: 113,512,919 (GRCm39) |
N871I |
unknown |
Het |
| Slc48a1 |
T |
G |
15: 97,687,833 (GRCm39) |
D62E |
probably damaging |
Het |
| Slc6a21 |
G |
A |
7: 44,936,398 (GRCm39) |
M157I |
|
Het |
| Slurp2 |
T |
C |
15: 74,614,961 (GRCm39) |
D60G |
probably benign |
Het |
| Sparcl1 |
G |
T |
5: 104,240,979 (GRCm39) |
N148K |
possibly damaging |
Het |
| Spata31e4 |
C |
T |
13: 50,856,128 (GRCm39) |
R589* |
probably null |
Het |
| Spsb2 |
T |
A |
6: 124,786,976 (GRCm39) |
N236K |
probably benign |
Het |
| Sptb |
G |
T |
12: 76,679,308 (GRCm39) |
|
probably benign |
Het |
| Ssc4d |
A |
T |
5: 135,990,030 (GRCm39) |
C41S |
probably damaging |
Het |
| Tecta |
A |
T |
9: 42,286,375 (GRCm39) |
D760E |
probably benign |
Het |
| Tesmin |
G |
T |
19: 3,439,431 (GRCm39) |
|
probably benign |
Het |
| Tiam1 |
A |
C |
16: 89,601,776 (GRCm39) |
|
probably benign |
Het |
| Tram1 |
T |
G |
1: 13,639,830 (GRCm39) |
I306L |
probably benign |
Het |
| Trank1 |
A |
C |
9: 111,191,500 (GRCm39) |
D503A |
probably damaging |
Het |
| Ttc21b |
T |
C |
2: 66,031,596 (GRCm39) |
H1044R |
|
Het |
| Ubac2 |
T |
C |
14: 122,145,626 (GRCm39) |
F95L |
probably benign |
Het |
| Vmn2r91 |
A |
T |
17: 18,326,296 (GRCm39) |
M194L |
probably benign |
Het |
| Yju2b |
C |
T |
8: 84,990,527 (GRCm39) |
R35Q |
probably damaging |
Het |
| Zdhhc1 |
G |
T |
8: 106,205,533 (GRCm39) |
H90Q |
probably damaging |
Het |
| Zfp169 |
C |
T |
13: 48,652,292 (GRCm39) |
V42I |
probably damaging |
Het |
| Zfp81 |
A |
G |
17: 33,553,387 (GRCm39) |
C476R |
probably damaging |
Het |
|
| Other mutations in Tnrc6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00335:Tnrc6a
|
APN |
7 |
122,770,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00580:Tnrc6a
|
APN |
7 |
122,773,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Tnrc6a
|
APN |
7 |
122,770,717 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02004:Tnrc6a
|
APN |
7 |
122,780,589 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02142:Tnrc6a
|
APN |
7 |
122,751,414 (GRCm39) |
intron |
probably benign |
|
|
IGL02220:Tnrc6a
|
APN |
7 |
122,769,679 (GRCm39) |
missense |
probably benign |
|
|
IGL02436:Tnrc6a
|
APN |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02670:Tnrc6a
|
APN |
7 |
122,770,535 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02743:Tnrc6a
|
APN |
7 |
122,770,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
0152:Tnrc6a
|
UTSW |
7 |
122,779,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Tnrc6a
|
UTSW |
7 |
122,770,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Tnrc6a
|
UTSW |
7 |
122,785,951 (GRCm39) |
splice site |
probably benign |
|
|
R0566:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0600:Tnrc6a
|
UTSW |
7 |
122,771,039 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0751:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1184:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1319:Tnrc6a
|
UTSW |
7 |
122,783,474 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Tnrc6a
|
UTSW |
7 |
122,776,098 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1709:Tnrc6a
|
UTSW |
7 |
122,769,205 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1776:Tnrc6a
|
UTSW |
7 |
122,770,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Tnrc6a
|
UTSW |
7 |
122,792,140 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1807:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R1876:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2010:Tnrc6a
|
UTSW |
7 |
122,770,269 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2086:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2089:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2511:Tnrc6a
|
UTSW |
7 |
122,770,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2830:Tnrc6a
|
UTSW |
7 |
122,792,172 (GRCm39) |
makesense |
probably null |
|
|
R2850:Tnrc6a
|
UTSW |
7 |
122,779,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Tnrc6a
|
UTSW |
7 |
122,780,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Tnrc6a
|
UTSW |
7 |
122,769,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Tnrc6a
|
UTSW |
7 |
122,770,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4439:Tnrc6a
|
UTSW |
7 |
122,751,405 (GRCm39) |
nonsense |
probably null |
|
|
R4525:Tnrc6a
|
UTSW |
7 |
122,779,005 (GRCm39) |
missense |
probably benign |
|
|
R4578:Tnrc6a
|
UTSW |
7 |
122,783,444 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4613:Tnrc6a
|
UTSW |
7 |
122,783,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4711:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Tnrc6a
|
UTSW |
7 |
122,791,313 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4746:Tnrc6a
|
UTSW |
7 |
122,789,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Tnrc6a
|
UTSW |
7 |
122,769,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Tnrc6a
|
UTSW |
7 |
122,791,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4967:Tnrc6a
|
UTSW |
7 |
122,789,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5064:Tnrc6a
|
UTSW |
7 |
122,785,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5239:Tnrc6a
|
UTSW |
7 |
122,785,842 (GRCm39) |
missense |
probably benign |
|
|
R5604:Tnrc6a
|
UTSW |
7 |
122,773,459 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5805:Tnrc6a
|
UTSW |
7 |
122,769,299 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5942:Tnrc6a
|
UTSW |
7 |
122,785,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Tnrc6a
|
UTSW |
7 |
122,781,603 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6212:Tnrc6a
|
UTSW |
7 |
122,742,965 (GRCm39) |
splice site |
probably null |
|
|
R6284:Tnrc6a
|
UTSW |
7 |
122,770,558 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6417:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6420:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Tnrc6a
|
UTSW |
7 |
122,769,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6760:Tnrc6a
|
UTSW |
7 |
122,771,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6886:Tnrc6a
|
UTSW |
7 |
122,786,668 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6968:Tnrc6a
|
UTSW |
7 |
122,781,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7216:Tnrc6a
|
UTSW |
7 |
122,770,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7260:Tnrc6a
|
UTSW |
7 |
122,785,813 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7299:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
|
|
R7322:Tnrc6a
|
UTSW |
7 |
122,770,731 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7500:Tnrc6a
|
UTSW |
7 |
122,772,673 (GRCm39) |
splice site |
probably null |
|
|
R7872:Tnrc6a
|
UTSW |
7 |
122,779,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8270:Tnrc6a
|
UTSW |
7 |
122,769,294 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8313:Tnrc6a
|
UTSW |
7 |
122,769,936 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8348:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8390:Tnrc6a
|
UTSW |
7 |
122,761,794 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8448:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8514:Tnrc6a
|
UTSW |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R8767:Tnrc6a
|
UTSW |
7 |
122,783,133 (GRCm39) |
unclassified |
probably benign |
|
|
R9147:Tnrc6a
|
UTSW |
7 |
122,785,667 (GRCm39) |
intron |
probably benign |
|
|
R9153:Tnrc6a
|
UTSW |
7 |
122,773,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9166:Tnrc6a
|
UTSW |
7 |
122,786,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9179:Tnrc6a
|
UTSW |
7 |
122,791,881 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9192:Tnrc6a
|
UTSW |
7 |
122,789,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Tnrc6a
|
UTSW |
7 |
122,778,958 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9778:Tnrc6a
|
UTSW |
7 |
122,769,635 (GRCm39) |
missense |
probably benign |
0.43 |
|
X0064:Tnrc6a
|
UTSW |
7 |
122,769,021 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1176:Tnrc6a
|
UTSW |
7 |
122,761,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTGGACCTTGGACTCTTTCC -3'
(R):5'- AAGGGTATGGTTGATTATGCTCAGATC -3'
Sequencing Primer
(F):5'- GTGATGACCAAGTACTTACATGTC -3'
(R):5'- CTTTGGAAATCTGAGGCC -3'
|
| Posted On |
2021-11-19 |
Incidental Mutation