Mutagenetix > Incidental Mutation

Incidental Mutation 'R9047:Tecta'

688127

Institutional Source

Beutler Lab

Gene Symbol

Tecta

Ensembl Gene

ENSMUSG00000037705

Gene Name

tectorin alpha

Synonyms

[a]-tectorin, Tctna

MMRRC Submission

068873-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.107) question?

Stock #

R9047 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

42240915-42311225 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 42286375 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 760 (D760E)

Ref Sequence

ENSEMBL: ENSMUSP00000040262 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042190] [ENSMUST00000160940]

AlphaFold

O08523

Predicted Effect

probably benign
Transcript: ENSMUST00000042190
AA Change: D760E

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)

SMART Domains

Protein: ENSMUSP00000040262
Gene: ENSMUSG00000037705
AA Change: D760E

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
NIDO	98	254	7.88e-77	SMART
VWC	260	314	1.04e0	SMART
VWD	312	477	1.5e-58	SMART
C8	517	592	7.06e-29	SMART
EGF_like	622	645	3.87e1	SMART
VWC	652	713	1.87e-1	SMART
VWD	703	865	4.44e-43	SMART
C8	905	981	9.19e-19	SMART
Pfam:TIL	984	1036	9.8e-13	PFAM
VWD	1090	1257	1.44e-51	SMART
C8	1294	1369	4.64e-15	SMART
EGF_like	1388	1420	5.34e1	SMART
VWC	1427	1487	2.88e-19	SMART
VWD	1477	1638	2.72e-38	SMART
C8	1684	1758	6.51e-10	SMART
ZP	1805	2059	2.95e-85	SMART
EGF	2087	2122	2.07e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000160940
AA Change: D760E

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000125370
Gene: ENSMUSG00000037705
AA Change: D760E

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
NIDO	98	254	7.88e-77	SMART
VWC	260	314	1.04e0	SMART
VWD	312	477	1.5e-58	SMART
C8	517	592	7.06e-29	SMART
EGF_like	622	645	3.87e1	SMART
VWC	652	713	1.87e-1	SMART
VWD	703	865	4.44e-43	SMART
C8	905	981	9.19e-19	SMART
Pfam:TIL	984	1036	6.1e-13	PFAM
VWD	1090	1257	1.44e-51	SMART
C8	1294	1369	4.64e-15	SMART
EGF_like	1388	1420	5.34e1	SMART
VWC	1427	1487	2.88e-19	SMART
VWD	1477	1638	2.72e-38	SMART
C8	1679	1753	6.51e-10	SMART
ZP	1800	2054	2.95e-85	SMART
EGF	2082	2117	2.07e1	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.9%
20x: 99.7%

Validation Efficiency

100% (76/76)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice exhibit a tectorial membrane that is detached from the cochlear epithelium. Though the basilar membranes of mutant mice are tuned, sensitivity is attenuated. Mice with an Y1870C mutation have a disrupted tectorial membrane, elevated neural thresholds and broadened neural tuning. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 80 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410004B18Rik	T	A	3: 145,644,848 (GRCm39)	S156T	probably damaging	Het
4930522L14Rik	A	G	5: 109,885,420 (GRCm39)	L146P		Het
Adra1a	T	A	14: 66,875,634 (GRCm39)	M203K	probably damaging	Het
Adtrp	G	A	13: 41,969,636 (GRCm39)	T89I	possibly damaging	Het
Akt3	G	T	1: 176,886,955 (GRCm39)	T298K	probably damaging	Het
Aldh4a1	G	T	4: 139,350,511 (GRCm39)		probably benign	Het
Aplf	T	C	6: 87,640,779 (GRCm39)	T77A	possibly damaging	Het
Arid4b	T	A	13: 14,355,815 (GRCm39)	W618R	probably damaging	Het
Asxl3	C	A	18: 22,585,465 (GRCm39)	P130Q	probably damaging	Het
Asxl3	A	G	18: 22,585,471 (GRCm39)	K132R	probably damaging	Het
Atp11a	T	C	8: 12,878,483 (GRCm39)	M353T	probably damaging	Het
Atp11b	A	G	3: 35,861,038 (GRCm39)	D375G	probably damaging	Het
Cage1	C	T	13: 38,201,338 (GRCm39)	A656T	possibly damaging	Het
Casz1	C	T	4: 149,023,497 (GRCm39)	P801S	probably damaging	Het
Cdc14b	A	T	13: 64,368,758 (GRCm39)		probably benign	Het
Cdin1	A	G	2: 115,607,504 (GRCm39)	T286A	probably benign	Het
Cox6b2	A	G	7: 4,755,086 (GRCm39)	F63L	probably benign	Het
Cramp1	A	C	17: 25,198,603 (GRCm39)	V773G	possibly damaging	Het
Cul7	A	G	17: 46,965,448 (GRCm39)	E542G	probably benign	Het
Cyp2c55	T	C	19: 39,019,790 (GRCm39)	Y243H	possibly damaging	Het
Dnah9	C	A	11: 65,962,925 (GRCm39)	D1797Y	possibly damaging	Het
Dpep2	C	A	8: 106,715,944 (GRCm39)	A298S		Het
Dvl3	G	A	16: 20,342,826 (GRCm39)		probably null	Het
Dynlt2a3	A	G	17: 15,187,942 (GRCm39)	Y111H	probably damaging	Het
Enpp3	T	C	10: 24,674,172 (GRCm39)	D376G	possibly damaging	Het
Ffar4	T	C	19: 38,102,232 (GRCm39)	I289T	possibly damaging	Het
Gm5565	T	C	5: 146,094,849 (GRCm39)	Y299C	probably damaging	Het
Gm57858	A	G	3: 36,087,033 (GRCm39)	I187T	probably benign	Het
Gpat3	A	T	5: 100,994,788 (GRCm39)	M39L	probably benign	Het
Gpr153	T	C	4: 152,364,664 (GRCm39)	L240P	probably damaging	Het
Gpr182	T	C	10: 127,586,517 (GRCm39)	I145V	probably benign	Het
H2-Q4	A	T	17: 35,598,969 (GRCm39)	T80S	possibly damaging	Het
Hnf1a	T	A	5: 115,088,882 (GRCm39)	T545S	probably benign	Het
Kif5b	A	C	18: 6,208,261 (GRCm39)	F946V	probably benign	Het
Krtap16-1	C	T	11: 99,877,167 (GRCm39)	C79Y	probably damaging	Het
Lama2	A	G	10: 26,882,697 (GRCm39)	V2622A	possibly damaging	Het
Lrrc37a	T	A	11: 103,391,375 (GRCm39)	Q1350L	probably damaging	Het
Map2k2	G	A	10: 80,955,498 (GRCm39)	V294I	probably benign	Het
Meak7	T	C	8: 120,489,050 (GRCm39)	N411S	probably benign	Het
Mtus1	G	A	8: 41,536,760 (GRCm39)	H319Y	possibly damaging	Het
Ncdn	T	C	4: 126,644,621 (GRCm39)	D67G	possibly damaging	Het
Ngef	G	A	1: 87,431,010 (GRCm39)	P269L	probably damaging	Het
Nlrp9b	A	G	7: 19,757,401 (GRCm39)	I213V	possibly damaging	Het
Nyap2	G	A	1: 81,275,803 (GRCm39)	R649H	possibly damaging	Het
Or14a258	A	G	7: 86,035,248 (GRCm39)	S207P	probably benign	Het
Or4a67	C	A	2: 88,598,299 (GRCm39)	R120L	probably damaging	Het
Or5d20-ps1	T	G	2: 87,931,416 (GRCm39)	D305A	unknown	Het
Pi4kb	T	A	3: 94,900,428 (GRCm39)	L354Q	probably damaging	Het
Plekhh2	T	C	17: 84,898,190 (GRCm39)	S944P	probably damaging	Het
Podn	C	T	4: 107,878,743 (GRCm39)	V375M	probably damaging	Het
Pramel12	C	A	4: 143,145,673 (GRCm39)	Q381K	possibly damaging	Het
Psmb2	T	A	4: 126,599,895 (GRCm39)	H110Q	probably benign	Het
Rasip1	A	G	7: 45,282,066 (GRCm39)	E523G	possibly damaging	Het
Ripor1	T	G	8: 106,342,783 (GRCm39)	C219G	probably damaging	Het
Rps6ka2	G	C	17: 7,567,678 (GRCm39)	V714L	probably damaging	Het
Sass6	G	T	3: 116,407,647 (GRCm39)	L254F	probably damaging	Het
Scarf2	G	A	16: 17,624,270 (GRCm39)	G525E	probably damaging	Het
Sh3d21	T	A	4: 126,046,131 (GRCm39)		probably benign	Het
Sh3tc1	C	A	5: 35,863,827 (GRCm39)	A787S	probably benign	Het
Skint5	T	A	4: 113,512,919 (GRCm39)	N871I	unknown	Het
Slc48a1	T	G	15: 97,687,833 (GRCm39)	D62E	probably damaging	Het
Slc6a21	G	A	7: 44,936,398 (GRCm39)	M157I		Het
Slurp2	T	C	15: 74,614,961 (GRCm39)	D60G	probably benign	Het
Sparcl1	G	T	5: 104,240,979 (GRCm39)	N148K	possibly damaging	Het
Spata31e4	C	T	13: 50,856,128 (GRCm39)	R589*	probably null	Het
Spsb2	T	A	6: 124,786,976 (GRCm39)	N236K	probably benign	Het
Sptb	G	T	12: 76,679,308 (GRCm39)		probably benign	Het
Ssc4d	A	T	5: 135,990,030 (GRCm39)	C41S	probably damaging	Het
Tesmin	G	T	19: 3,439,431 (GRCm39)		probably benign	Het
Tiam1	A	C	16: 89,601,776 (GRCm39)		probably benign	Het
Tnrc6a	T	C	7: 122,778,946 (GRCm39)	L1219S	probably damaging	Het
Tram1	T	G	1: 13,639,830 (GRCm39)	I306L	probably benign	Het
Trank1	A	C	9: 111,191,500 (GRCm39)	D503A	probably damaging	Het
Ttc21b	T	C	2: 66,031,596 (GRCm39)	H1044R		Het
Ubac2	T	C	14: 122,145,626 (GRCm39)	F95L	probably benign	Het
Vmn2r91	A	T	17: 18,326,296 (GRCm39)	M194L	probably benign	Het
Yju2b	C	T	8: 84,990,527 (GRCm39)	R35Q	probably damaging	Het
Zdhhc1	G	T	8: 106,205,533 (GRCm39)	H90Q	probably damaging	Het
Zfp169	C	T	13: 48,652,292 (GRCm39)	V42I	probably damaging	Het
Zfp81	A	G	17: 33,553,387 (GRCm39)	C476R	probably damaging	Het

Other mutations in Tecta

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00466:Tecta	APN	9	42,243,844 (GRCm39)	missense	probably damaging	1.00
IGL00925:Tecta	APN	9	42,286,331 (GRCm39)	missense	probably benign
IGL00960:Tecta	APN	9	42,270,376 (GRCm39)	missense	possibly damaging	0.74
IGL00974:Tecta	APN	9	42,242,670 (GRCm39)	missense	probably benign	0.00
IGL01070:Tecta	APN	9	42,306,299 (GRCm39)	missense	probably damaging	1.00
IGL01284:Tecta	APN	9	42,256,916 (GRCm39)	missense	probably damaging	1.00
IGL01324:Tecta	APN	9	42,256,727 (GRCm39)	missense	probably damaging	1.00
IGL01694:Tecta	APN	9	42,278,475 (GRCm39)	missense	possibly damaging	0.92
IGL01861:Tecta	APN	9	42,284,658 (GRCm39)	missense	probably benign
IGL02010:Tecta	APN	9	42,248,489 (GRCm39)	missense	probably damaging	0.97
IGL02397:Tecta	APN	9	42,306,294 (GRCm39)	missense	probably damaging	1.00
IGL03031:Tecta	APN	9	42,256,789 (GRCm39)	missense	probably benign
IGL03208:Tecta	APN	9	42,248,396 (GRCm39)	splice site	probably benign
IGL03249:Tecta	APN	9	42,303,182 (GRCm39)	missense	probably benign	0.20
cover	UTSW	9	42,255,183 (GRCm39)	missense	probably benign	0.05
lid	UTSW	9	42,284,406 (GRCm39)	missense	probably damaging	0.99
R0004:Tecta	UTSW	9	42,256,774 (GRCm39)	missense	possibly damaging	0.74
R0045:Tecta	UTSW	9	42,286,487 (GRCm39)	missense	probably damaging	1.00
R0045:Tecta	UTSW	9	42,286,487 (GRCm39)	missense	probably damaging	1.00
R0119:Tecta	UTSW	9	42,263,359 (GRCm39)	missense	probably damaging	1.00
R0133:Tecta	UTSW	9	42,278,524 (GRCm39)	missense	probably benign	0.00
R0157:Tecta	UTSW	9	42,286,307 (GRCm39)	missense	probably benign
R0180:Tecta	UTSW	9	42,278,109 (GRCm39)	missense	probably benign
R0299:Tecta	UTSW	9	42,263,359 (GRCm39)	missense	probably damaging	1.00
R0345:Tecta	UTSW	9	42,295,514 (GRCm39)	missense	probably damaging	0.98
R0370:Tecta	UTSW	9	42,278,100 (GRCm39)	missense	probably benign
R0465:Tecta	UTSW	9	42,270,714 (GRCm39)	missense	possibly damaging	0.62
R0466:Tecta	UTSW	9	42,284,369 (GRCm39)	missense	probably benign
R0479:Tecta	UTSW	9	42,249,235 (GRCm39)	missense	probably damaging	1.00
R0498:Tecta	UTSW	9	42,288,910 (GRCm39)	missense	probably damaging	1.00
R0499:Tecta	UTSW	9	42,263,359 (GRCm39)	missense	probably damaging	1.00
R0519:Tecta	UTSW	9	42,259,188 (GRCm39)	splice site	probably benign
R0584:Tecta	UTSW	9	42,259,204 (GRCm39)	missense	possibly damaging	0.79
R0589:Tecta	UTSW	9	42,256,930 (GRCm39)	missense	probably benign	0.01
R0607:Tecta	UTSW	9	42,299,501 (GRCm39)	missense	probably damaging	1.00
R0691:Tecta	UTSW	9	42,295,637 (GRCm39)	missense	probably damaging	1.00
R0905:Tecta	UTSW	9	42,250,290 (GRCm39)	missense	probably damaging	1.00
R1216:Tecta	UTSW	9	42,289,203 (GRCm39)	missense	probably benign	0.44
R1239:Tecta	UTSW	9	42,243,781 (GRCm39)	missense	probably damaging	1.00
R1442:Tecta	UTSW	9	42,243,778 (GRCm39)	missense	probably damaging	1.00
R1553:Tecta	UTSW	9	42,259,482 (GRCm39)	missense	probably damaging	1.00
R1727:Tecta	UTSW	9	42,270,597 (GRCm39)	missense	probably damaging	0.96
R1728:Tecta	UTSW	9	42,303,218 (GRCm39)	missense	probably benign	0.12
R1729:Tecta	UTSW	9	42,303,218 (GRCm39)	missense	probably benign	0.12
R1762:Tecta	UTSW	9	42,286,605 (GRCm39)	missense	probably benign	0.30
R1778:Tecta	UTSW	9	42,254,927 (GRCm39)	missense	probably damaging	1.00
R1795:Tecta	UTSW	9	42,289,345 (GRCm39)	missense	probably benign
R1796:Tecta	UTSW	9	42,295,493 (GRCm39)	missense	probably damaging	1.00
R1866:Tecta	UTSW	9	42,303,320 (GRCm39)	missense	probably damaging	0.97
R1871:Tecta	UTSW	9	42,248,636 (GRCm39)	missense	probably damaging	1.00
R1871:Tecta	UTSW	9	42,248,472 (GRCm39)	missense	probably damaging	0.98
R1911:Tecta	UTSW	9	42,249,232 (GRCm39)	missense	probably damaging	1.00
R2074:Tecta	UTSW	9	42,248,575 (GRCm39)	nonsense	probably null
R2135:Tecta	UTSW	9	42,251,581 (GRCm39)	missense	probably damaging	1.00
R2171:Tecta	UTSW	9	42,270,220 (GRCm39)	missense	probably damaging	0.99
R2220:Tecta	UTSW	9	42,303,326 (GRCm39)	missense	probably damaging	1.00
R2372:Tecta	UTSW	9	42,299,570 (GRCm39)	missense	probably damaging	1.00
R2570:Tecta	UTSW	9	42,243,848 (GRCm39)	missense	probably damaging	1.00
R2939:Tecta	UTSW	9	42,289,290 (GRCm39)	missense	possibly damaging	0.63
R2940:Tecta	UTSW	9	42,289,290 (GRCm39)	missense	possibly damaging	0.63
R3081:Tecta	UTSW	9	42,289,290 (GRCm39)	missense	possibly damaging	0.63
R3407:Tecta	UTSW	9	42,249,150 (GRCm39)	missense	probably damaging	1.00
R3732:Tecta	UTSW	9	42,303,402 (GRCm39)	missense	possibly damaging	0.95
R3771:Tecta	UTSW	9	42,242,292 (GRCm39)	missense	probably damaging	1.00
R3772:Tecta	UTSW	9	42,242,292 (GRCm39)	missense	probably damaging	1.00
R3773:Tecta	UTSW	9	42,242,292 (GRCm39)	missense	probably damaging	1.00
R3832:Tecta	UTSW	9	42,250,329 (GRCm39)	missense	probably damaging	1.00
R4378:Tecta	UTSW	9	42,278,004 (GRCm39)	missense	probably damaging	1.00
R4480:Tecta	UTSW	9	42,284,529 (GRCm39)	missense	possibly damaging	0.75
R4485:Tecta	UTSW	9	42,248,570 (GRCm39)	missense	possibly damaging	0.73
R4804:Tecta	UTSW	9	42,309,533 (GRCm39)	missense	probably benign
R4869:Tecta	UTSW	9	42,286,830 (GRCm39)	missense	probably benign	0.02
R4944:Tecta	UTSW	9	42,241,573 (GRCm39)	missense	probably benign	0.05
R5008:Tecta	UTSW	9	42,284,358 (GRCm39)	missense	possibly damaging	0.76
R5014:Tecta	UTSW	9	42,284,538 (GRCm39)	missense	probably damaging	1.00
R5125:Tecta	UTSW	9	42,286,481 (GRCm39)	missense	probably damaging	1.00
R5178:Tecta	UTSW	9	42,286,481 (GRCm39)	missense	probably damaging	1.00
R5180:Tecta	UTSW	9	42,248,504 (GRCm39)	missense	probably damaging	1.00
R5214:Tecta	UTSW	9	42,256,964 (GRCm39)	missense	probably benign	0.04
R5230:Tecta	UTSW	9	42,306,239 (GRCm39)	missense	probably damaging	0.96
R5330:Tecta	UTSW	9	42,249,152 (GRCm39)	missense	probably damaging	1.00
R5387:Tecta	UTSW	9	42,286,359 (GRCm39)	missense	probably damaging	0.98
R5614:Tecta	UTSW	9	42,250,351 (GRCm39)	missense	probably damaging	1.00
R5708:Tecta	UTSW	9	42,250,222 (GRCm39)	missense	probably damaging	1.00
R5738:Tecta	UTSW	9	42,284,474 (GRCm39)	missense	possibly damaging	0.63
R5770:Tecta	UTSW	9	42,256,885 (GRCm39)	missense	possibly damaging	0.94
R5839:Tecta	UTSW	9	42,284,272 (GRCm39)	missense	possibly damaging	0.86
R5839:Tecta	UTSW	9	42,242,319 (GRCm39)	missense	probably benign	0.03
R6119:Tecta	UTSW	9	42,284,371 (GRCm39)	missense	probably benign	0.00
R6246:Tecta	UTSW	9	42,289,204 (GRCm39)	missense	probably benign	0.07
R6377:Tecta	UTSW	9	42,255,051 (GRCm39)	missense	probably damaging	1.00
R6416:Tecta	UTSW	9	42,286,563 (GRCm39)	missense	probably damaging	0.97
R6595:Tecta	UTSW	9	42,295,523 (GRCm39)	missense	probably damaging	1.00
R6850:Tecta	UTSW	9	42,255,134 (GRCm39)	missense	probably benign	0.20
R6859:Tecta	UTSW	9	42,303,425 (GRCm39)	missense	probably damaging	1.00
R6861:Tecta	UTSW	9	42,248,633 (GRCm39)	missense	possibly damaging	0.93
R6939:Tecta	UTSW	9	42,259,293 (GRCm39)	missense	probably damaging	1.00
R6996:Tecta	UTSW	9	42,278,082 (GRCm39)	missense	probably benign
R7069:Tecta	UTSW	9	42,306,237 (GRCm39)	missense	probably benign	0.03
R7104:Tecta	UTSW	9	42,278,239 (GRCm39)	missense	probably benign	0.00
R7129:Tecta	UTSW	9	42,259,287 (GRCm39)	missense	probably damaging	1.00
R7220:Tecta	UTSW	9	42,255,183 (GRCm39)	missense	probably benign	0.05
R7251:Tecta	UTSW	9	42,299,048 (GRCm39)	missense	probably damaging	1.00
R7307:Tecta	UTSW	9	42,289,288 (GRCm39)	missense	probably damaging	1.00
R7343:Tecta	UTSW	9	42,248,628 (GRCm39)	missense	probably damaging	1.00
R7355:Tecta	UTSW	9	42,278,438 (GRCm39)	nonsense	probably null
R7635:Tecta	UTSW	9	42,242,283 (GRCm39)	missense	probably benign	0.11
R7653:Tecta	UTSW	9	42,248,532 (GRCm39)	missense	probably damaging	1.00
R7723:Tecta	UTSW	9	42,278,232 (GRCm39)	missense	probably damaging	1.00
R7939:Tecta	UTSW	9	42,299,519 (GRCm39)	missense	probably damaging	0.99
R7966:Tecta	UTSW	9	42,306,258 (GRCm39)	missense	probably damaging	0.98
R7967:Tecta	UTSW	9	42,289,251 (GRCm39)	missense	possibly damaging	0.95
R8000:Tecta	UTSW	9	42,278,480 (GRCm39)	nonsense	probably null
R8064:Tecta	UTSW	9	42,306,251 (GRCm39)	missense	possibly damaging	0.94
R8117:Tecta	UTSW	9	42,288,927 (GRCm39)	missense	probably damaging	1.00
R8176:Tecta	UTSW	9	42,270,465 (GRCm39)	missense	probably damaging	0.97
R8284:Tecta	UTSW	9	42,289,325 (GRCm39)	missense	possibly damaging	0.89
R8315:Tecta	UTSW	9	42,299,121 (GRCm39)	critical splice acceptor site	probably null
R8321:Tecta	UTSW	9	42,284,349 (GRCm39)	missense	probably damaging	1.00
R8332:Tecta	UTSW	9	42,286,310 (GRCm39)	missense	probably damaging	1.00
R8437:Tecta	UTSW	9	42,243,856 (GRCm39)	missense	probably damaging	0.98
R8496:Tecta	UTSW	9	42,241,547 (GRCm39)	missense	probably benign	0.01
R8514:Tecta	UTSW	9	42,284,406 (GRCm39)	missense	probably damaging	0.99
R8683:Tecta	UTSW	9	42,278,268 (GRCm39)	missense	probably damaging	0.96
R8856:Tecta	UTSW	9	42,284,597 (GRCm39)	missense	probably benign	0.13
R8886:Tecta	UTSW	9	42,278,359 (GRCm39)	missense	probably benign	0.37
R9106:Tecta	UTSW	9	42,278,479 (GRCm39)	missense	probably benign	0.05
R9332:Tecta	UTSW	9	42,284,193 (GRCm39)	missense	probably damaging	1.00
R9352:Tecta	UTSW	9	42,249,147 (GRCm39)	missense	probably damaging	1.00
R9462:Tecta	UTSW	9	42,248,576 (GRCm39)	missense	probably damaging	1.00
R9535:Tecta	UTSW	9	42,270,759 (GRCm39)	missense	probably damaging	0.99
R9564:Tecta	UTSW	9	42,249,123 (GRCm39)	missense	probably damaging	0.97
R9592:Tecta	UTSW	9	42,250,238 (GRCm39)	missense	probably damaging	1.00
R9715:Tecta	UTSW	9	42,286,596 (GRCm39)	missense	probably damaging	1.00
Z1176:Tecta	UTSW	9	42,303,390 (GRCm39)	missense	probably damaging	0.99
Z1177:Tecta	UTSW	9	42,286,872 (GRCm39)	missense	probably benign	0.00
Z1177:Tecta	UTSW	9	42,303,366 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCCCAGCCAGAGGAAGAATG -3'
(R):5'- GATGTCTACTGCTTCAACAAGACC -3'

Sequencing Primer
(F):5'- CAGCCAGAGGAAGAATGTCAAGTC -3'
(R):5'- TCAACAAGACCTGCCGGAGTG -3'

Posted On

2021-11-19