Mutagenetix > Incidental Mutation

Incidental Mutation 'R9051:Igsf10'

688343

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

6530405F15Rik, CMF608, Adlican2

MMRRC Submission

068877-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.194) question?

Stock #

R9051 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

59224156-59251815 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 59236668 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Serine at position 1171 (L1171S)

Ref Sequence

ENSEMBL: ENSMUSP00000037246 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000193455] [ENSMUST00000194546]

AlphaFold

Q3V1M1

Predicted Effect

probably benign
Transcript: ENSMUST00000039419
AA Change: L1171S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: L1171S

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000193455
AA Change: L1171S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: L1171S

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000194546
AA Change: L1171S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: L1171S

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.9%
20x: 99.6%

Validation Efficiency

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	A	T	11: 9,285,232 (GRCm39)	T3289S	probably damaging	Het
Actr1b	G	T	1: 36,740,534 (GRCm39)	Q240K	probably benign	Het
Adamts19	T	C	18: 59,034,048 (GRCm39)	V341A	probably damaging	Het
Akirin2	C	A	4: 34,551,148 (GRCm39)	S35*	probably null	Het
Alg3	G	T	16: 20,427,765 (GRCm39)	Q90K	probably benign	Het
Alox12	C	T	11: 70,138,153 (GRCm39)	R394H	possibly damaging	Het
Ankrd17	A	C	5: 90,411,134 (GRCm39)	M1387R	probably damaging	Het
Anp32b	T	G	4: 46,468,592 (GRCm39)	F121V	possibly damaging	Het
Atp2b2	A	G	6: 113,740,566 (GRCm39)	V815A	probably damaging	Het
Atxn7l1	T	C	12: 33,417,420 (GRCm39)	L527S	probably benign	Het
B9d2	C	T	7: 25,385,462 (GRCm39)	L91F	possibly damaging	Het
Bcl2l11	T	A	2: 128,000,221 (GRCm39)	I188N	probably damaging	Het
Bnc2	A	C	4: 84,210,138 (GRCm39)	S744A	probably benign	Het
Casr	T	G	16: 36,330,414 (GRCm39)	M307L	probably benign	Het
Cd109	CATTTATTTATTTATTTATTTATTTATTTATTTAT	CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT	9: 78,619,782 (GRCm39)		probably benign	Het
Cd109	TTATA	TTATATATA	9: 78,619,813 (GRCm39)		probably benign	Het
Cd22	A	G	7: 30,575,449 (GRCm39)	S198P	probably benign	Het
Cd37	C	A	7: 44,886,622 (GRCm39)	V99L	probably benign	Het
Cdkn1c	A	G	7: 143,013,964 (GRCm39)	S161P	possibly damaging	Het
Chi3l1	G	T	1: 134,111,919 (GRCm39)		probably null	Het
Col4a2	T	C	8: 11,498,198 (GRCm39)	F1669S	probably damaging	Het
Dchs2	A	T	3: 83,261,493 (GRCm39)	H2587L	probably benign	Het
Ddx19a	A	T	8: 111,710,228 (GRCm39)	M124K	probably benign	Het
Dnhd1	A	T	7: 105,341,933 (GRCm39)	H1244L	possibly damaging	Het
Dnpep	G	A	1: 75,292,329 (GRCm39)	P165L	probably damaging	Het
Dpp3	T	C	19: 4,973,172 (GRCm39)	R141G	probably benign	Het
Dpysl3	T	C	18: 43,462,814 (GRCm39)	D521G	probably damaging	Het
Dusp4	T	A	8: 35,284,345 (GRCm39)	M220K	probably damaging	Het
Duxf4	G	A	10: 58,071,711 (GRCm39)	P168S	probably damaging	Het
Edc4	T	A	8: 106,613,833 (GRCm39)	L391Q	probably damaging	Het
Edrf1	A	C	7: 133,273,207 (GRCm39)	I1221L	probably benign	Het
Elavl2	A	G	4: 91,199,847 (GRCm39)	L12P	probably benign	Het
Fastkd3	T	A	13: 68,733,071 (GRCm39)	V464D	probably damaging	Het
Flt4	C	A	11: 49,527,598 (GRCm39)	N920K	probably benign	Het
Gimap3	T	C	6: 48,742,259 (GRCm39)	T224A	probably benign	Het
Gm9772	T	A	17: 22,225,565 (GRCm39)	K112*	probably null	Het
Gp5	C	A	16: 30,127,976 (GRCm39)	V233L		Het
Gpr25	A	T	1: 136,188,026 (GRCm39)	W196R	probably benign	Het
Hs3st4	G	A	7: 123,582,680 (GRCm39)	G93S	probably damaging	Het
Itgb7	C	T	15: 102,126,359 (GRCm39)	G526S	possibly damaging	Het
Kcnh8	G	A	17: 53,141,642 (GRCm39)	C295Y	probably damaging	Het
Klhl8	A	G	5: 104,015,709 (GRCm39)		probably null	Het
Krt1c	T	A	15: 101,726,317 (GRCm39)	I74F	unknown	Het
Lamp5	G	T	2: 135,911,054 (GRCm39)	M262I	probably benign	Het
Lrp5	G	T	19: 3,680,156 (GRCm39)	R443S	possibly damaging	Het
Lrrc66	G	T	5: 73,765,267 (GRCm39)	A592E	probably benign	Het
Lrrc66	C	T	5: 73,765,268 (GRCm39)	A592T	probably benign	Het
Mettl23	T	A	11: 116,744,865 (GRCm39)	V93D	unknown	Het
Mier2	G	A	10: 79,384,274 (GRCm39)	R166W	probably damaging	Het
Mkrn2os	G	A	6: 115,562,325 (GRCm39)	R213W	probably benign	Het
Mrps36	T	A	13: 100,877,715 (GRCm39)	I22L	probably damaging	Het
Msantd5f4	A	G	4: 73,557,185 (GRCm39)	N6S	possibly damaging	Het
Myocd	T	C	11: 65,077,795 (GRCm39)	R667G	probably benign	Het
Ncapg	T	A	5: 45,853,140 (GRCm39)	L869M	probably damaging	Het
Ndst3	T	C	3: 123,465,549 (GRCm39)	N141S	probably benign	Het
Neu2	A	T	1: 87,524,965 (GRCm39)	R317*	probably null	Het
Nf1	G	T	11: 79,364,168 (GRCm39)	V1533F	probably damaging	Het
Npy4r	T	A	14: 33,869,083 (GRCm39)	R68S	possibly damaging	Het
Nr1h5	T	C	3: 102,853,427 (GRCm39)	H360R	probably null	Het
Or1x6	G	A	11: 50,938,938 (GRCm39)	M1I	probably null	Het
Or4f14c	T	C	2: 111,941,441 (GRCm39)	D52G	probably damaging	Het
Or9s15	T	C	1: 92,524,978 (GRCm39)	S246P	probably damaging	Het
Osmr	A	C	15: 6,882,027 (GRCm39)	V39G	probably damaging	Het
Plekhm2	T	C	4: 141,359,732 (GRCm39)	D345G	possibly damaging	Het
Prkaa2	G	T	4: 104,906,600 (GRCm39)	S165*	probably null	Het
Qser1	A	T	2: 104,593,292 (GRCm39)	F1575Y	possibly damaging	Het
Rasl11a	C	A	5: 146,782,107 (GRCm39)	D27E	probably benign	Het
Ret	A	T	6: 118,142,888 (GRCm39)	Y929*	probably null	Het
Samd9l	T	A	6: 3,373,493 (GRCm39)	E1256V	probably benign	Het
Scnn1g	A	G	7: 121,341,566 (GRCm39)	I243V	possibly damaging	Het
Slc6a3	C	T	13: 73,718,031 (GRCm39)	R514*	probably null	Het
Sorcs3	C	T	19: 48,194,809 (GRCm39)	A64V	probably benign	Het
Sos1	G	T	17: 80,715,723 (GRCm39)	N1011K	probably benign	Het
Srbd1	C	A	17: 86,428,115 (GRCm39)	A373S	possibly damaging	Het
Tas1r1	C	T	4: 152,122,833 (GRCm39)	W4*	probably null	Het
Tcf15	C	T	2: 151,985,690 (GRCm39)	R49C	probably damaging	Het
Tex30	A	G	1: 44,127,136 (GRCm39)	V124A	possibly damaging	Het
Tgif1	T	C	17: 71,151,882 (GRCm39)	D243G		Het
Tgtp1	T	G	11: 48,877,916 (GRCm39)	D263A	probably damaging	Het
Themis3	T	A	17: 66,862,864 (GRCm39)	T365S	probably benign	Het
Thoc2l	C	A	5: 104,666,818 (GRCm39)	P447T	probably benign	Het
Tprg1	A	T	16: 25,231,662 (GRCm39)	I213F	probably damaging	Het
Traf4	A	T	11: 78,052,005 (GRCm39)	C160S	probably damaging	Het
Trio	T	C	15: 27,732,770 (GRCm39)	E3037G	possibly damaging	Het
Ttbk2	G	T	2: 120,575,911 (GRCm39)	S1022*	probably null	Het
Ttc6	T	C	12: 57,783,949 (GRCm39)	Y1803H	probably damaging	Het
Ttn	A	C	2: 76,549,452 (GRCm39)	Y31742D	probably benign	Het
Ttn	G	T	2: 76,617,595 (GRCm39)	P16292Q	probably damaging	Het
Ubr5	A	G	15: 38,002,503 (GRCm39)	V1510A		Het
Vac14	A	G	8: 111,379,869 (GRCm39)	D389G	probably benign	Het
Vwa8	A	G	14: 79,324,150 (GRCm39)	D1151G	probably benign	Het
Zfp608	T	C	18: 55,032,266 (GRCm39)	N558S	probably damaging	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,238,960 (GRCm39)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,226,938 (GRCm39)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,238,548 (GRCm39)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,238,018 (GRCm39)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,235,203 (GRCm39)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,238,945 (GRCm39)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,227,071 (GRCm39)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,226,651 (GRCm39)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,237,452 (GRCm39)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,236,756 (GRCm39)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,233,432 (GRCm39)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,226,158 (GRCm39)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,226,081 (GRCm39)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,233,399 (GRCm39)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,238,573 (GRCm39)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,238,111 (GRCm39)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,235,652 (GRCm39)	missense	probably benign
IGL02494:Igsf10	APN	3	59,235,427 (GRCm39)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,236,662 (GRCm39)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,226,027 (GRCm39)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,238,285 (GRCm39)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,226,339 (GRCm39)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,226,905 (GRCm39)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,227,086 (GRCm39)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,235,586 (GRCm39)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,239,321 (GRCm39)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,243,632 (GRCm39)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,238,481 (GRCm39)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,226,531 (GRCm39)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,235,579 (GRCm39)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,233,000 (GRCm39)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,225,903 (GRCm39)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,238,045 (GRCm39)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,233,429 (GRCm39)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,238,253 (GRCm39)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,227,527 (GRCm39)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,236,089 (GRCm39)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,236,296 (GRCm39)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,227,188 (GRCm39)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,233,483 (GRCm39)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,236,015 (GRCm39)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,238,525 (GRCm39)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,239,269 (GRCm39)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,235,196 (GRCm39)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,226,188 (GRCm39)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,237,838 (GRCm39)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,233,583 (GRCm39)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,238,706 (GRCm39)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,235,921 (GRCm39)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,226,514 (GRCm39)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,236,617 (GRCm39)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,238,693 (GRCm39)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,236,993 (GRCm39)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,243,998 (GRCm39)	missense	possibly damaging	0.77
R2155:Igsf10	UTSW	3	59,239,101 (GRCm39)	missense	probably damaging	1.00
R2509:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,232,875 (GRCm39)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,239,157 (GRCm39)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,236,848 (GRCm39)	missense	probably benign
R3547:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,237,962 (GRCm39)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,243,752 (GRCm39)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,233,135 (GRCm39)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,233,546 (GRCm39)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,239,345 (GRCm39)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,235,981 (GRCm39)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,227,152 (GRCm39)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,226,171 (GRCm39)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,236,972 (GRCm39)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,237,521 (GRCm39)	missense	probably benign
R4676:Igsf10	UTSW	3	59,233,370 (GRCm39)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,227,751 (GRCm39)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,237,126 (GRCm39)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,236,027 (GRCm39)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,226,143 (GRCm39)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,235,714 (GRCm39)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,233,694 (GRCm39)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,227,553 (GRCm39)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,233,175 (GRCm39)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,235,574 (GRCm39)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,226,492 (GRCm39)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,237,832 (GRCm39)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,238,252 (GRCm39)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,235,578 (GRCm39)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,243,894 (GRCm39)	missense	probably damaging	1.00
R6145:Igsf10	UTSW	3	59,239,077 (GRCm39)	missense	possibly damaging	0.83
R6222:Igsf10	UTSW	3	59,226,336 (GRCm39)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,232,931 (GRCm39)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,235,928 (GRCm39)	missense	possibly damaging	0.88
R6283:Igsf10	UTSW	3	59,226,870 (GRCm39)	missense	probably damaging	1.00
R6336:Igsf10	UTSW	3	59,237,760 (GRCm39)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,236,992 (GRCm39)	missense	probably benign	0.06
R6785:Igsf10	UTSW	3	59,226,665 (GRCm39)	missense	probably damaging	1.00
R6873:Igsf10	UTSW	3	59,235,865 (GRCm39)	missense	probably benign
R6889:Igsf10	UTSW	3	59,239,354 (GRCm39)	missense	probably benign
R7024:Igsf10	UTSW	3	59,239,122 (GRCm39)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,238,501 (GRCm39)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,236,326 (GRCm39)	missense	probably benign
R7251:Igsf10	UTSW	3	59,226,875 (GRCm39)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,236,837 (GRCm39)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,233,189 (GRCm39)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,239,222 (GRCm39)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,226,775 (GRCm39)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,226,761 (GRCm39)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,233,612 (GRCm39)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,238,964 (GRCm39)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,236,549 (GRCm39)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,235,489 (GRCm39)	missense	probably benign	0.00
R7850:Igsf10	UTSW	3	59,227,053 (GRCm39)	missense	probably benign	0.33
R7879:Igsf10	UTSW	3	59,238,145 (GRCm39)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,235,748 (GRCm39)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,235,832 (GRCm39)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,227,125 (GRCm39)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,239,279 (GRCm39)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,237,130 (GRCm39)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,236,380 (GRCm39)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,237,949 (GRCm39)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,238,036 (GRCm39)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,236,254 (GRCm39)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,225,954 (GRCm39)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,238,949 (GRCm39)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,236,564 (GRCm39)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,227,431 (GRCm39)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,226,308 (GRCm39)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,238,063 (GRCm39)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,243,876 (GRCm39)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,237,410 (GRCm39)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,243,633 (GRCm39)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,233,739 (GRCm39)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,226,888 (GRCm39)	missense	possibly damaging	0.69
R9178:Igsf10	UTSW	3	59,233,480 (GRCm39)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,236,526 (GRCm39)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,226,869 (GRCm39)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,237,904 (GRCm39)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,233,624 (GRCm39)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,237,106 (GRCm39)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,227,199 (GRCm39)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,239,126 (GRCm39)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,237,359 (GRCm39)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,237,026 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- GGAGGAACCATGATCTGTGG -3'
(R):5'- ACTGTGGTCAAGAAGCCATC -3'

Sequencing Primer
(F):5'- AAGAGGAGCTTTTTCAGGAGGCTTAG -3'
(R):5'- CTGTGGTCAAGAAGCCATCTTTAC -3'

Posted On

2021-11-19