Incidental Mutation 'R8927:Copa'
| ID |
690116 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Copa
|
| Ensembl Gene |
ENSMUSG00000026553 |
| Gene Name |
coatomer protein complex subunit alpha |
| Synonyms |
xenin |
| MMRRC Submission |
068771-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.971)
|
| Stock # |
R8927 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
171910096-171949897 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 171931737 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 329
(H329Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027833]
[ENSMUST00000124289]
[ENSMUST00000135192]
|
| AlphaFold |
Q8CIE6 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000027833
AA Change: H329Q
PolyPhen 2
Score 0.592 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000027833
Gene: ENSMUSG00000026553
AA Change: H329Q
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
37 |
2.86e0 |
SMART |
|
WD40
|
40 |
79 |
1.11e-6 |
SMART |
|
WD40
|
82 |
121 |
4.76e-6 |
SMART |
|
WD40
|
124 |
163 |
2.24e-11 |
SMART |
|
WD40
|
194 |
233 |
2.98e-7 |
SMART |
|
WD40
|
238 |
277 |
8.42e-7 |
SMART |
|
WD40
|
280 |
318 |
1.38e1 |
SMART |
|
Pfam:Coatomer_WDAD
|
338 |
776 |
5.4e-144 |
PFAM |
|
Pfam:COPI_C
|
824 |
1233 |
1.4e-190 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124289
|
| SMART Domains |
Protein: ENSMUSP00000118899
Gene: ENSMUSG00000026553
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:WD40
|
1 |
37 |
2e-19 |
BLAST |
|
PDB:4J8G|B
|
1 |
52 |
2e-23 |
PDB |
|
SCOP:d1erja_
|
1 |
52 |
1e-6 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000135192
AA Change: H329Q
PolyPhen 2
Score 0.030 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000118179
Gene: ENSMUSG00000026553
AA Change: H329Q
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
37 |
2.86e0 |
SMART |
|
WD40
|
40 |
79 |
1.11e-6 |
SMART |
|
WD40
|
82 |
121 |
4.76e-6 |
SMART |
|
WD40
|
124 |
163 |
2.24e-11 |
SMART |
|
WD40
|
194 |
233 |
2.98e-7 |
SMART |
|
WD40
|
238 |
277 |
8.42e-7 |
SMART |
|
WD40
|
280 |
318 |
1.38e1 |
SMART |
|
Pfam:Coatomer_WDAD
|
338 |
767 |
1.1e-148 |
PFAM |
|
Pfam:COPI_C
|
815 |
1224 |
3.6e-216 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123214
Gene: ENSMUSG00000026553
AA Change: H104Q
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
14 |
53 |
8.42e-7 |
SMART |
|
WD40
|
56 |
94 |
1.38e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
99% (78/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(6) : Gene trapped(6)
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A630089N07Rik |
A |
T |
16: 97,867,367 (GRCm39) |
H198Q |
probably damaging |
Het |
| Abcb9 |
T |
C |
5: 124,221,706 (GRCm39) |
T223A |
probably benign |
Het |
| Actc1 |
T |
A |
2: 113,880,881 (GRCm39) |
K115* |
probably null |
Het |
| Angptl2 |
G |
A |
2: 33,132,316 (GRCm39) |
D308N |
probably benign |
Het |
| Arl4d |
A |
C |
11: 101,557,892 (GRCm39) |
Q139H |
possibly damaging |
Het |
| Aspm |
T |
A |
1: 139,418,125 (GRCm39) |
C2951* |
probably null |
Het |
| Atp23 |
A |
T |
10: 126,723,362 (GRCm39) |
*247R |
probably null |
Het |
| B3gnt7 |
T |
A |
1: 86,232,839 (GRCm39) |
S28R |
probably benign |
Het |
| Bmp7 |
C |
T |
2: 172,721,211 (GRCm39) |
R288H |
probably damaging |
Het |
| Bsdc1 |
G |
T |
4: 129,355,439 (GRCm39) |
|
probably benign |
Het |
| Capn13 |
T |
C |
17: 73,631,761 (GRCm39) |
|
probably null |
Het |
| Ccdc146 |
T |
C |
5: 21,538,060 (GRCm39) |
E88G |
probably damaging |
Het |
| Ccdc73 |
C |
A |
2: 104,822,542 (GRCm39) |
D2E |
|
Het |
| Cdc5l |
C |
A |
17: 45,721,839 (GRCm39) |
R477L |
|
Het |
| Cdh22 |
T |
A |
2: 164,965,504 (GRCm39) |
H529L |
possibly damaging |
Het |
| Chchd3 |
T |
A |
6: 32,780,951 (GRCm39) |
E178D |
probably benign |
Het |
| Ciz1 |
A |
T |
2: 32,257,512 (GRCm39) |
R186* |
probably null |
Het |
| Col4a2 |
A |
G |
8: 11,475,543 (GRCm39) |
|
probably null |
Het |
| Dcaf7 |
A |
G |
11: 105,942,752 (GRCm39) |
D233G |
probably damaging |
Het |
| Dclk2 |
G |
T |
3: 86,739,048 (GRCm39) |
P317Q |
probably damaging |
Het |
| Dgat2 |
T |
C |
7: 98,818,710 (GRCm39) |
Y90C |
probably benign |
Het |
| Dsc3 |
A |
T |
18: 20,107,234 (GRCm39) |
H462Q |
probably benign |
Het |
| Fam151a |
T |
A |
4: 106,603,242 (GRCm39) |
|
probably benign |
Het |
| Fn1 |
T |
C |
1: 71,638,535 (GRCm39) |
N1998S |
probably benign |
Het |
| Fpr2 |
T |
C |
17: 18,113,724 (GRCm39) |
L240S |
possibly damaging |
Het |
| Fzd9 |
A |
T |
5: 135,278,589 (GRCm39) |
M432K |
probably damaging |
Het |
| Gm5862 |
T |
A |
5: 26,226,678 (GRCm39) |
I75F |
probably damaging |
Het |
| Gpr45 |
T |
A |
1: 43,072,314 (GRCm39) |
V319D |
probably damaging |
Het |
| H4c11 |
T |
C |
13: 21,919,525 (GRCm39) |
V87A |
possibly damaging |
Het |
| Igfn1 |
T |
A |
1: 135,905,984 (GRCm39) |
R275W |
probably damaging |
Het |
| Inafm1 |
G |
A |
7: 16,006,980 (GRCm39) |
A79V |
unknown |
Het |
| Itfg1 |
C |
T |
8: 86,567,420 (GRCm39) |
|
probably benign |
Het |
| Kcnt2 |
T |
A |
1: 140,356,535 (GRCm39) |
|
probably null |
Het |
| Klhl35 |
T |
G |
7: 99,120,221 (GRCm39) |
I366S |
probably damaging |
Het |
| Lysmd1 |
A |
T |
3: 95,045,831 (GRCm39) |
I223F |
probably damaging |
Het |
| Mrps30 |
A |
G |
13: 118,523,205 (GRCm39) |
L189P |
probably damaging |
Het |
| Ms4a4d |
A |
C |
19: 11,533,574 (GRCm39) |
T152P |
probably benign |
Het |
| Mtcl1 |
A |
T |
17: 66,755,628 (GRCm39) |
I238K |
probably benign |
Het |
| Musk |
T |
C |
4: 58,301,638 (GRCm39) |
I132T |
probably damaging |
Het |
| Myh2 |
A |
T |
11: 67,079,509 (GRCm39) |
M989L |
probably benign |
Het |
| Myh8 |
G |
A |
11: 67,174,081 (GRCm39) |
R172H |
probably benign |
Het |
| Nt5c1a |
C |
T |
4: 123,102,281 (GRCm39) |
T69M |
possibly damaging |
Het |
| Nuak2 |
T |
A |
1: 132,255,916 (GRCm39) |
D196E |
probably damaging |
Het |
| Or52h7 |
A |
T |
7: 104,214,229 (GRCm39) |
H267L |
probably damaging |
Het |
| Or5ap2 |
A |
T |
2: 85,679,918 (GRCm39) |
I41F |
possibly damaging |
Het |
| Or5t7 |
T |
C |
2: 86,507,630 (GRCm39) |
T16A |
probably benign |
Het |
| Or8k53 |
T |
C |
2: 86,178,090 (GRCm39) |
T7A |
possibly damaging |
Het |
| Or8s10 |
A |
G |
15: 98,336,519 (GRCm39) |
|
probably benign |
Het |
| Palb2 |
A |
T |
7: 121,723,821 (GRCm39) |
C643S |
probably damaging |
Het |
| Pde5a |
T |
A |
3: 122,633,249 (GRCm39) |
I706N |
probably damaging |
Het |
| Pdlim4 |
T |
C |
11: 53,950,790 (GRCm39) |
R100G |
probably benign |
Het |
| Pip5k1c |
T |
A |
10: 81,128,906 (GRCm39) |
V5E |
possibly damaging |
Het |
| Pira1 |
A |
C |
7: 3,742,358 (GRCm39) |
N56K |
probably benign |
Het |
| Plekhm1 |
A |
G |
11: 103,268,039 (GRCm39) |
V644A |
probably benign |
Het |
| Plk2 |
T |
G |
13: 110,535,750 (GRCm39) |
V524G |
probably damaging |
Het |
| Ppl |
T |
A |
16: 4,905,474 (GRCm39) |
N1607I |
probably benign |
Het |
| Prag1 |
T |
G |
8: 36,614,360 (GRCm39) |
V1304G |
probably damaging |
Het |
| Prex1 |
C |
T |
2: 166,426,995 (GRCm39) |
V1077M |
probably damaging |
Het |
| Prmt6 |
T |
C |
3: 110,158,248 (GRCm39) |
S14G |
probably benign |
Het |
| Psrc1 |
T |
G |
3: 108,293,973 (GRCm39) |
S263R |
probably damaging |
Het |
| Qrfprl |
C |
A |
6: 65,358,597 (GRCm39) |
S107* |
probably null |
Het |
| Rbp7 |
A |
T |
4: 149,537,958 (GRCm39) |
L36* |
probably null |
Het |
| Rgs12 |
G |
T |
5: 35,123,633 (GRCm39) |
W472L |
possibly damaging |
Het |
| Rrp8 |
C |
A |
7: 105,384,073 (GRCm39) |
C143F |
possibly damaging |
Het |
| Sart1 |
T |
C |
19: 5,438,529 (GRCm39) |
S43G |
probably benign |
Het |
| Setx |
A |
G |
2: 29,016,971 (GRCm39) |
T25A |
possibly damaging |
Het |
| Skint5 |
G |
A |
4: 113,341,099 (GRCm39) |
T1414I |
probably benign |
Het |
| Sorbs2 |
T |
A |
8: 46,248,952 (GRCm39) |
S734R |
probably damaging |
Het |
| Spata31g1 |
A |
T |
4: 42,972,251 (GRCm39) |
Y528F |
probably benign |
Het |
| Spon1 |
T |
C |
7: 113,629,592 (GRCm39) |
|
probably null |
Het |
| Sptbn1 |
C |
T |
11: 30,088,962 (GRCm39) |
V767I |
probably damaging |
Het |
| Srf |
T |
C |
17: 46,860,095 (GRCm39) |
I477V |
probably damaging |
Het |
| Tanc2 |
A |
G |
11: 105,701,331 (GRCm39) |
Y282C |
probably damaging |
Het |
| Tbc1d23 |
A |
G |
16: 56,992,152 (GRCm39) |
Y603H |
probably damaging |
Het |
| Tdpoz6 |
T |
A |
3: 93,599,950 (GRCm39) |
T140S |
probably benign |
Het |
| Tfap4 |
T |
C |
16: 4,369,218 (GRCm39) |
D134G |
probably damaging |
Het |
| Tmem200c |
A |
G |
17: 69,148,733 (GRCm39) |
T439A |
probably benign |
Het |
| Tmem63b |
A |
T |
17: 45,975,908 (GRCm39) |
M515K |
probably damaging |
Het |
| Tnc |
A |
T |
4: 63,925,595 (GRCm39) |
N980K |
probably damaging |
Het |
| Ttc23l |
T |
A |
15: 10,530,720 (GRCm39) |
L297F |
probably damaging |
Het |
| Vinac1 |
A |
G |
2: 128,882,789 (GRCm39) |
S76P |
|
Het |
| Vmn1r170 |
A |
G |
7: 23,305,814 (GRCm39) |
N72S |
possibly damaging |
Het |
| Vmn2r8 |
T |
C |
5: 108,950,131 (GRCm39) |
M239V |
|
Het |
| Vopp1 |
A |
G |
6: 57,731,578 (GRCm39) |
F138L |
probably damaging |
Het |
| Vps41 |
T |
A |
13: 18,929,501 (GRCm39) |
F79I |
probably benign |
Het |
| Zfp317 |
T |
C |
9: 19,552,521 (GRCm39) |
M1T |
probably null |
Het |
|
| Other mutations in Copa |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00848:Copa
|
APN |
1 |
171,938,255 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01360:Copa
|
APN |
1 |
171,915,155 (GRCm39) |
splice site |
probably null |
|
|
IGL01434:Copa
|
APN |
1 |
171,947,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01744:Copa
|
APN |
1 |
171,940,756 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01837:Copa
|
APN |
1 |
171,946,419 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01988:Copa
|
APN |
1 |
171,945,831 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02059:Copa
|
APN |
1 |
171,927,320 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02123:Copa
|
APN |
1 |
171,939,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02731:Copa
|
APN |
1 |
171,929,785 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL03114:Copa
|
APN |
1 |
171,946,835 (GRCm39) |
nonsense |
probably null |
|
|
P0027:Copa
|
UTSW |
1 |
171,939,515 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
PIT4434001:Copa
|
UTSW |
1 |
171,933,742 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0233:Copa
|
UTSW |
1 |
171,915,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0465:Copa
|
UTSW |
1 |
171,945,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0547:Copa
|
UTSW |
1 |
171,949,254 (GRCm39) |
splice site |
probably benign |
|
|
R0568:Copa
|
UTSW |
1 |
171,939,704 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0628:Copa
|
UTSW |
1 |
171,918,592 (GRCm39) |
splice site |
probably benign |
|
|
R1328:Copa
|
UTSW |
1 |
171,949,258 (GRCm39) |
splice site |
probably benign |
|
|
R1494:Copa
|
UTSW |
1 |
171,931,694 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1728:Copa
|
UTSW |
1 |
171,939,554 (GRCm39) |
missense |
probably benign |
|
|
R1758:Copa
|
UTSW |
1 |
171,931,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1784:Copa
|
UTSW |
1 |
171,939,554 (GRCm39) |
missense |
probably benign |
|
|
R1942:Copa
|
UTSW |
1 |
171,939,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2054:Copa
|
UTSW |
1 |
171,946,524 (GRCm39) |
nonsense |
probably null |
|
|
R2299:Copa
|
UTSW |
1 |
171,949,292 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2518:Copa
|
UTSW |
1 |
171,947,468 (GRCm39) |
missense |
probably benign |
|
|
R2680:Copa
|
UTSW |
1 |
171,948,971 (GRCm39) |
nonsense |
probably null |
|
|
R3080:Copa
|
UTSW |
1 |
171,940,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3161:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3973:Copa
|
UTSW |
1 |
171,948,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3975:Copa
|
UTSW |
1 |
171,948,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4031:Copa
|
UTSW |
1 |
171,935,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Copa
|
UTSW |
1 |
171,928,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4227:Copa
|
UTSW |
1 |
171,945,682 (GRCm39) |
intron |
probably benign |
|
|
R4244:Copa
|
UTSW |
1 |
171,938,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4254:Copa
|
UTSW |
1 |
171,929,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Copa
|
UTSW |
1 |
171,919,964 (GRCm39) |
intron |
probably benign |
|
|
R4323:Copa
|
UTSW |
1 |
171,946,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4402:Copa
|
UTSW |
1 |
171,929,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4711:Copa
|
UTSW |
1 |
171,947,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4721:Copa
|
UTSW |
1 |
171,931,841 (GRCm39) |
splice site |
probably benign |
|
|
R4773:Copa
|
UTSW |
1 |
171,932,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4794:Copa
|
UTSW |
1 |
171,946,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Copa
|
UTSW |
1 |
171,919,843 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4953:Copa
|
UTSW |
1 |
171,910,453 (GRCm39) |
unclassified |
probably benign |
|
|
R5139:Copa
|
UTSW |
1 |
171,948,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5152:Copa
|
UTSW |
1 |
171,945,628 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5297:Copa
|
UTSW |
1 |
171,940,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5586:Copa
|
UTSW |
1 |
171,932,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5698:Copa
|
UTSW |
1 |
171,946,511 (GRCm39) |
nonsense |
probably null |
|
|
R6283:Copa
|
UTSW |
1 |
171,946,415 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6921:Copa
|
UTSW |
1 |
171,939,491 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6934:Copa
|
UTSW |
1 |
171,938,253 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7009:Copa
|
UTSW |
1 |
171,918,567 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7194:Copa
|
UTSW |
1 |
171,947,511 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7348:Copa
|
UTSW |
1 |
171,929,790 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7710:Copa
|
UTSW |
1 |
171,937,411 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7745:Copa
|
UTSW |
1 |
171,939,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7893:Copa
|
UTSW |
1 |
171,947,132 (GRCm39) |
nonsense |
probably null |
|
|
R8168:Copa
|
UTSW |
1 |
171,927,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8273:Copa
|
UTSW |
1 |
171,946,546 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8704:Copa
|
UTSW |
1 |
171,931,693 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8754:Copa
|
UTSW |
1 |
171,935,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8757:Copa
|
UTSW |
1 |
171,947,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8759:Copa
|
UTSW |
1 |
171,947,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8885:Copa
|
UTSW |
1 |
171,925,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8891:Copa
|
UTSW |
1 |
171,946,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8928:Copa
|
UTSW |
1 |
171,931,737 (GRCm39) |
missense |
probably null |
0.03 |
|
R8956:Copa
|
UTSW |
1 |
171,937,480 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9063:Copa
|
UTSW |
1 |
171,944,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9295:Copa
|
UTSW |
1 |
171,939,823 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9364:Copa
|
UTSW |
1 |
171,944,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9437:Copa
|
UTSW |
1 |
171,931,712 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9673:Copa
|
UTSW |
1 |
171,945,648 (GRCm39) |
missense |
probably benign |
0.11 |
|
T0722:Copa
|
UTSW |
1 |
171,939,515 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Copa
|
UTSW |
1 |
171,933,690 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACCTAGGCACAGTCCATCTC -3'
(R):5'- GGCAGTCCATATCTGACAGCTG -3'
Sequencing Primer
(F):5'- GTCCATCTCCAAGCTGTAGTAGATG -3'
(R):5'- CAGTCCATATCTGACAGCTGAGATTC -3'
|
| Posted On |
2021-11-19 |
Incidental Mutation