Mutagenetix > Incidental Mutation

Incidental Mutation 'R9090:Hmcn1'

690862

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

EG545370, LOC240793

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9090 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

150438275-150869186 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 150632309 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 876 (I876T)

Ref Sequence

ENSEMBL: ENSMUSP00000074340 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000074783
AA Change: I876T

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: I876T

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000137197
AA Change: I876T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: I876T

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 106 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aatk	A	T	11: 119,901,940 (GRCm39)	S819T	probably damaging	Het
Abca13	A	T	11: 9,241,698 (GRCm39)	D1187V	probably damaging	Het
Ak9	C	A	10: 41,300,623 (GRCm39)	T1611K	unknown	Het
Als2	G	T	1: 59,242,189 (GRCm39)	T622K	probably benign	Het
Ankrd40	G	A	11: 94,225,262 (GRCm39)	A98T	probably benign	Het
Ap1b1	T	C	11: 4,973,174 (GRCm39)	L339P	probably damaging	Het
Appl1	A	C	14: 26,669,084 (GRCm39)	H363Q	probably benign	Het
Atf6	T	C	1: 170,622,245 (GRCm39)	N459D	probably damaging	Het
Ccdc6	A	T	10: 70,024,993 (GRCm39)	Q432L	unknown	Het
Ccl21a	T	A	4: 42,773,486 (GRCm39)	Q84L	probably damaging	Het
Cct4	A	G	11: 22,951,389 (GRCm39)	I348V	probably benign	Het
Cd300ld2	A	G	11: 114,904,550 (GRCm39)	Y106H	probably damaging	Het
Cdh19	C	T	1: 110,876,947 (GRCm39)	E131K	probably damaging	Het
Cdon	A	G	9: 35,403,175 (GRCm39)	D1095G	probably damaging	Het
Cep85l	T	A	10: 53,157,670 (GRCm39)	R678*	probably null	Het
Chst3	T	A	10: 60,021,465 (GRCm39)	S461C	probably damaging	Het
Clk1	A	G	1: 58,459,312 (GRCm39)	I149T	possibly damaging	Het
Clvs2	T	A	10: 33,389,301 (GRCm39)	D313V	possibly damaging	Het
Dap3	T	C	3: 88,840,913 (GRCm39)	T75A	probably benign	Het
Dnaaf1	T	A	8: 120,324,392 (GRCm39)	F631L	probably benign	Het
Dnah14	A	T	1: 181,597,325 (GRCm39)	N3549I	probably benign	Het
Dnah17	A	T	11: 117,931,870 (GRCm39)	Y3701N	probably damaging	Het
Dock6	A	G	9: 21,752,796 (GRCm39)	V339A	possibly damaging	Het
Dpp6	T	A	5: 27,803,832 (GRCm39)	C259*	probably null	Het
Dqx1	A	G	6: 83,036,024 (GRCm39)	T119A	probably benign	Het
Dync1h1	G	T	12: 110,583,310 (GRCm39)	R469L	probably benign	Het
Eno4	C	T	19: 58,951,260 (GRCm39)	A424V	probably benign	Het
Entrep1	A	T	19: 23,972,221 (GRCm39)	I161N	possibly damaging	Het
Fads1	T	A	19: 10,163,162 (GRCm39)	D146E	probably damaging	Het
Fam171a1	C	T	2: 3,224,543 (GRCm39)	T303M	probably damaging	Het
Fbxw20	C	T	9: 109,050,423 (GRCm39)	D401N	probably benign	Het
Fcho1	T	A	8: 72,163,068 (GRCm39)	T654S	possibly damaging	Het
Flad1	C	A	3: 89,315,858 (GRCm39)	E235*	probably null	Het
Flrt2	G	T	12: 95,745,907 (GRCm39)	A82S	probably benign	Het
Gabrg3	A	T	7: 56,829,386 (GRCm39)	S124T	probably benign	Het
Galt	C	T	4: 41,756,777 (GRCm39)	T139I	probably benign	Het
Garin4	A	G	1: 190,895,153 (GRCm39)	S497P	probably damaging	Het
Gfod1	T	C	13: 43,456,861 (GRCm39)	E38G	possibly damaging	Het
Gm10330	A	G	12: 23,829,992 (GRCm39)	I63T	possibly damaging	Het
Gm49359	A	G	13: 62,602,867 (GRCm39)	V111A	probably benign	Het
Gpank1	C	T	17: 35,340,734 (GRCm39)		probably benign	Het
Hck	T	C	2: 152,973,185 (GRCm39)	L156P	probably damaging	Het
Hcn3	G	T	3: 89,057,267 (GRCm39)	R444S	probably damaging	Het
Hephl1	T	C	9: 14,988,236 (GRCm39)	N624S	probably damaging	Het
Ifi207	CTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATAGAGTTGCATATGGAGCCAGGAGGATGCTATATGTTGTTGATGAAGTTGCATGTGGAGCCAGGAG	CTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATAGAGTTGCATATGGAGCCAGGAGGATGCTATATGTTGTTGATGAAGTTGCATGTGGAGCCAGGAG	1: 173,556,762 (GRCm39)		probably benign	Het
Itga9	T	A	9: 118,500,859 (GRCm39)	D377E	possibly damaging	Het
Itpr3	G	A	17: 27,337,651 (GRCm39)		probably benign	Het
Itprid1	G	T	6: 55,944,051 (GRCm39)	R417L	probably benign	Het
Klk1b11	C	T	7: 43,425,954 (GRCm39)	L32F	probably benign	Het
Lta4h	A	G	10: 93,310,412 (GRCm39)	S427G	probably benign	Het
Lxn	T	A	3: 67,368,651 (GRCm39)	I122F	probably damaging	Het
Lyz1	A	G	10: 117,124,492 (GRCm39)	V148A	possibly damaging	Het
Mael	G	T	1: 166,032,424 (GRCm39)	Q326K	probably benign	Het
Magi3	T	C	3: 103,923,264 (GRCm39)	D1151G	possibly damaging	Het
Map3k9	C	A	12: 81,769,261 (GRCm39)	G929V	probably benign	Het
Mcoln1	A	G	8: 3,555,771 (GRCm39)	Y22C	probably damaging	Het
Mier3	G	T	13: 111,827,870 (GRCm39)	M45I	probably benign	Het
Mrpl1	T	C	5: 96,371,746 (GRCm39)	V91A	probably damaging	Het
Myo7a	T	C	7: 97,740,281 (GRCm39)	H571R	probably benign	Het
Myom1	T	A	17: 71,374,325 (GRCm39)	W601R	probably damaging	Het
Myom3	C	T	4: 135,505,479 (GRCm39)	T456I	probably benign	Het
Nags	A	T	11: 102,037,584 (GRCm39)	H225L	probably benign	Het
Ncaph	C	A	2: 126,958,554 (GRCm39)	K488N	probably damaging	Het
Nkain3	C	T	4: 20,484,897 (GRCm39)	R60H	probably damaging	Het
Nlrp9a	A	T	7: 26,261,944 (GRCm39)	M698L	probably benign	Het
Nmur2	A	C	11: 55,931,308 (GRCm39)	I134M	probably benign	Het
Nrp2	A	C	1: 62,784,670 (GRCm39)	E273A	probably benign	Het
Nup85	A	G	11: 115,468,787 (GRCm39)	D210G	possibly damaging	Het
Obscn	A	G	11: 59,006,643 (GRCm39)	F1173S	probably damaging	Het
Or5ac24	A	T	16: 59,165,145 (GRCm39)	C306*	probably null	Het
Otogl	T	A	10: 107,652,974 (GRCm39)	E1126V	probably null	Het
Pfkl	T	C	10: 77,833,426 (GRCm39)	I259V	probably benign	Het
Phkg1	A	T	5: 129,893,863 (GRCm39)	Y291N	probably benign	Het
Piezo2	T	G	18: 63,163,450 (GRCm39)	H2156P	probably damaging	Het
Piezo2	C	A	18: 63,208,790 (GRCm39)	V1408L	probably damaging	Het
Pira13	T	A	7: 3,819,997 (GRCm39)	E640V	unknown	Het
Plekhg3	A	G	12: 76,622,694 (GRCm39)	T646A	probably benign	Het
Plk5	C	G	10: 80,193,830 (GRCm39)	R40G	probably damaging	Het
Ppp1r12a	T	C	10: 108,098,224 (GRCm39)	S838P	probably damaging	Het
Rarb	A	T	14: 16,435,235 (GRCm38)	Y270*	probably null	Het
Rbm15	T	C	3: 107,239,312 (GRCm39)	E362G	possibly damaging	Het
Rcan1	A	G	16: 92,262,741 (GRCm39)	F76L		Het
Rdh19	T	C	10: 127,696,142 (GRCm39)	L298P	probably damaging	Het
Rims1	T	A	1: 22,498,773 (GRCm39)	H57L		Het
Rlf	T	C	4: 121,004,751 (GRCm39)	T1520A	probably benign	Het
Rnase1	T	A	14: 51,382,964 (GRCm39)	H130L	possibly damaging	Het
Samd8	T	A	14: 21,842,569 (GRCm39)	M360K	probably damaging	Het
Samhd1	A	G	2: 156,956,205 (GRCm39)	L329P	probably damaging	Het
Scube1	C	T	15: 83,494,394 (GRCm39)	E878K	probably damaging	Het
Sema3b	T	C	9: 107,476,154 (GRCm39)	Y689C	probably damaging	Het
Semp2l2a	T	C	8: 13,886,697 (GRCm39)	T465A	possibly damaging	Het
Sh3pxd2b	A	T	11: 32,373,361 (GRCm39)	N843Y	possibly damaging	Het
Slco1a6	C	T	6: 142,035,575 (GRCm39)	C583Y	probably damaging	Het
Smg1	A	C	7: 117,811,786 (GRCm39)	V88G	unknown	Het
Spata24	T	A	18: 35,790,054 (GRCm39)	N146Y	probably damaging	Het
Tcf3	C	A	10: 80,253,191 (GRCm39)	V258L	probably benign	Het
Tiam2	T	C	17: 3,465,011 (GRCm39)	Y247H	probably damaging	Het
Ticrr	T	C	7: 79,310,604 (GRCm39)	F173L	possibly damaging	Het
Tpp2	A	G	1: 43,993,811 (GRCm39)	E232G	probably damaging	Het
Trank1	T	A	9: 111,174,547 (GRCm39)	V138E	probably damaging	Het
Ttll3	T	C	6: 113,369,596 (GRCm39)	S47P	probably benign	Het
Utp4	C	T	8: 107,632,857 (GRCm39)	T280M	probably damaging	Het
Vmn1r123	A	T	7: 20,896,794 (GRCm39)	N229Y	probably benign	Het
Vmn1r85	A	T	7: 12,818,942 (GRCm39)	Y67*	probably null	Het
Zbtb12	T	A	17: 35,114,320 (GRCm39)	V35E	possibly damaging	Het
Zmym6	T	A	4: 127,017,854 (GRCm39)	F1212I	probably damaging	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,553,029 (GRCm39)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,514,750 (GRCm39)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,682,117 (GRCm39)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,540,687 (GRCm39)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,532,485 (GRCm39)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,506,091 (GRCm39)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,486,464 (GRCm39)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,480,757 (GRCm39)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,458,052 (GRCm39)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,514,620 (GRCm39)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,502,784 (GRCm39)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,508,303 (GRCm39)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,498,675 (GRCm39)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,620,752 (GRCm39)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,594,991 (GRCm39)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,468,848 (GRCm39)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,734,990 (GRCm39)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,480,823 (GRCm39)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,485,382 (GRCm39)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,474,148 (GRCm39)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,503,164 (GRCm39)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,547,783 (GRCm39)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,455,984 (GRCm39)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,613,050 (GRCm39)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,459,031 (GRCm39)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,620,711 (GRCm39)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,547,789 (GRCm39)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,491,051 (GRCm39)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,566,352 (GRCm39)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,618,011 (GRCm39)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,543,638 (GRCm39)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,608,643 (GRCm39)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,479,622 (GRCm39)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,491,049 (GRCm39)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,579,932 (GRCm39)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,598,358 (GRCm39)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,439,349 (GRCm39)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,682,152 (GRCm39)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,540,666 (GRCm39)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,678,648 (GRCm39)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,868,774 (GRCm39)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,685,477 (GRCm39)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,573,244 (GRCm39)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,620,746 (GRCm39)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,494,760 (GRCm39)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,480,654 (GRCm39)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,532,445 (GRCm39)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,522,583 (GRCm39)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,439,579 (GRCm39)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,551,725 (GRCm39)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,453,029 (GRCm39)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,532,958 (GRCm39)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,573,273 (GRCm39)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,547,668 (GRCm39)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,684,290 (GRCm39)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,678,660 (GRCm39)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,619,418 (GRCm39)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,646,103 (GRCm39)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,648,261 (GRCm39)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,474,175 (GRCm39)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,505,982 (GRCm39)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,608,661 (GRCm39)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,577,720 (GRCm39)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,539,623 (GRCm39)	missense	probably damaging	1.00
Backbone	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
Cambrian	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
chordate	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
Justamere	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
notochord	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,614,409 (GRCm39)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,596,440 (GRCm39)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,684,488 (GRCm39)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,545,238 (GRCm39)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,684,427 (GRCm39)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,528,302 (GRCm39)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,553,157 (GRCm39)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,684,398 (GRCm39)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,553,075 (GRCm39)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,539,630 (GRCm39)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,479,562 (GRCm39)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,674,565 (GRCm39)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,591,573 (GRCm39)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,608,543 (GRCm39)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,735,003 (GRCm39)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,752,170 (GRCm39)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,618,092 (GRCm39)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,594,868 (GRCm39)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,525,768 (GRCm39)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,485,552 (GRCm39)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,533,127 (GRCm39)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,469,767 (GRCm39)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,674,470 (GRCm39)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,695,161 (GRCm39)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,684,538 (GRCm39)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,629,416 (GRCm39)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,525,824 (GRCm39)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,453,128 (GRCm39)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,624,777 (GRCm39)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,629,405 (GRCm39)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,623,942 (GRCm39)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,556,466 (GRCm39)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,522,545 (GRCm39)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,528,257 (GRCm39)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,485,451 (GRCm39)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,648,303 (GRCm39)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,545,172 (GRCm39)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,649,554 (GRCm39)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,610,283 (GRCm39)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,532,992 (GRCm39)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,620,778 (GRCm39)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,545,309 (GRCm39)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,506,084 (GRCm39)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,441,120 (GRCm39)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,551,735 (GRCm39)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,734,937 (GRCm39)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,474,781 (GRCm39)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,439,319 (GRCm39)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,624,834 (GRCm39)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,502,903 (GRCm39)	missense	probably damaging	0.98
R1794:Hmcn1	UTSW	1	150,474,036 (GRCm39)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,597,415 (GRCm39)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,532,944 (GRCm39)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,479,563 (GRCm39)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,596,446 (GRCm39)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,453,046 (GRCm39)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,533,202 (GRCm39)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,868,606 (GRCm39)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,480,633 (GRCm39)	missense	probably benign	0.28
R1959:Hmcn1	UTSW	1	150,525,427 (GRCm39)	missense	probably benign	0.00
R1960:Hmcn1	UTSW	1	150,553,127 (GRCm39)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,551,742 (GRCm39)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,614,364 (GRCm39)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,553,085 (GRCm39)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,453,074 (GRCm39)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,509,410 (GRCm39)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,591,566 (GRCm39)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,474,761 (GRCm39)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,500,349 (GRCm39)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,579,977 (GRCm39)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,528,429 (GRCm39)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,498,685 (GRCm39)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,441,135 (GRCm39)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,736,092 (GRCm39)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,474,783 (GRCm39)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,490,972 (GRCm39)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,562,618 (GRCm39)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,649,571 (GRCm39)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,619,398 (GRCm39)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,528,326 (GRCm39)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,506,403 (GRCm39)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,678,624 (GRCm39)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,624,786 (GRCm39)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,565,269 (GRCm39)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,620,776 (GRCm39)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,678,575 (GRCm39)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,462,169 (GRCm39)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,525,328 (GRCm39)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,462,716 (GRCm39)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,566,361 (GRCm39)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,449,320 (GRCm39)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,598,204 (GRCm39)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,598,120 (GRCm39)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,648,253 (GRCm39)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,534,259 (GRCm39)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,471,750 (GRCm39)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,533,210 (GRCm39)	missense	probably null
R4493:Hmcn1	UTSW	1	150,577,650 (GRCm39)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,509,417 (GRCm39)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,439,531 (GRCm39)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,610,238 (GRCm39)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,614,396 (GRCm39)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,471,645 (GRCm39)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,551,262 (GRCm39)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,500,301 (GRCm39)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,494,816 (GRCm39)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,648,322 (GRCm39)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,570,584 (GRCm39)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,565,346 (GRCm39)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,453,363 (GRCm39)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,468,836 (GRCm39)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,553,130 (GRCm39)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,598,286 (GRCm39)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,752,111 (GRCm39)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,695,200 (GRCm39)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,556,439 (GRCm39)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,613,007 (GRCm39)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,486,420 (GRCm39)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,532,492 (GRCm39)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,522,452 (GRCm39)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,471,612 (GRCm39)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,555,265 (GRCm39)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,458,047 (GRCm39)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,631,123 (GRCm39)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,498,995 (GRCm39)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,577,723 (GRCm39)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,485,576 (GRCm39)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,619,539 (GRCm39)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,631,042 (GRCm39)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,613,257 (GRCm39)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,453,290 (GRCm39)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,532,318 (GRCm39)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,534,313 (GRCm39)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,485,529 (GRCm39)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,566,351 (GRCm39)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,485,417 (GRCm39)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,570,600 (GRCm39)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,634,225 (GRCm39)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,684,448 (GRCm39)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,449,305 (GRCm39)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,570,629 (GRCm39)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,550,098 (GRCm39)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,525,358 (GRCm39)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,613,275 (GRCm39)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,868,774 (GRCm39)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,506,078 (GRCm39)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,474,648 (GRCm39)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,453,047 (GRCm39)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,532,973 (GRCm39)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,439,568 (GRCm39)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,579,924 (GRCm39)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,678,646 (GRCm39)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,508,188 (GRCm39)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,539,660 (GRCm39)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,646,081 (GRCm39)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,631,045 (GRCm39)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,631,044 (GRCm39)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,506,978 (GRCm39)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,494,687 (GRCm39)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,441,176 (GRCm39)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,522,535 (GRCm39)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,614,432 (GRCm39)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,573,170 (GRCm39)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,573,227 (GRCm39)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,620,711 (GRCm39)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,868,670 (GRCm39)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,540,535 (GRCm39)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,553,053 (GRCm39)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,459,029 (GRCm39)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,573,317 (GRCm39)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,470,869 (GRCm39)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,599,008 (GRCm39)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,619,547 (GRCm39)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,634,057 (GRCm39)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,620,784 (GRCm39)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,579,926 (GRCm39)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,610,269 (GRCm39)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,868,802 (GRCm39)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,475,404 (GRCm39)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,649,641 (GRCm39)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,479,853 (GRCm39)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,736,118 (GRCm39)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,479,997 (GRCm39)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,576,292 (GRCm39)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,452,961 (GRCm39)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,539,624 (GRCm39)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,562,605 (GRCm39)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,624,744 (GRCm39)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,629,450 (GRCm39)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,525,331 (GRCm39)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,514,627 (GRCm39)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,598,394 (GRCm39)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,591,574 (GRCm39)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,458,088 (GRCm39)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,559,466 (GRCm39)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,608,880 (GRCm39)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,479,565 (GRCm39)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,514,617 (GRCm39)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,559,496 (GRCm39)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,543,640 (GRCm39)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,682,196 (GRCm39)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,494,597 (GRCm39)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,439,382 (GRCm39)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,522,421 (GRCm39)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,550,181 (GRCm39)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,596,510 (GRCm39)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,506,017 (GRCm39)	nonsense	probably null
R7454:Hmcn1	UTSW	1	150,439,355 (GRCm39)	missense	probably damaging	1.00
R7476:Hmcn1	UTSW	1	150,456,018 (GRCm39)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,552,985 (GRCm39)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,498,718 (GRCm39)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,532,324 (GRCm39)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,562,531 (GRCm39)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,480,625 (GRCm39)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,531,586 (GRCm39)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,532,885 (GRCm39)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,441,080 (GRCm39)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,522,460 (GRCm39)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,543,631 (GRCm39)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,598,196 (GRCm39)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,632,343 (GRCm39)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,646,030 (GRCm39)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,682,172 (GRCm39)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,620,722 (GRCm39)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,468,940 (GRCm39)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,540,643 (GRCm39)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,525,835 (GRCm39)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,531,606 (GRCm39)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,540,629 (GRCm39)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,474,062 (GRCm39)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,525,743 (GRCm39)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,532,256 (GRCm39)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,624,841 (GRCm39)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,734,957 (GRCm39)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,629,411 (GRCm39)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,480,705 (GRCm39)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,522,409 (GRCm39)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,598,265 (GRCm39)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,453,228 (GRCm39)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,469,761 (GRCm39)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,695,117 (GRCm39)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,735,005 (GRCm39)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,614,515 (GRCm39)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,614,485 (GRCm39)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,634,142 (GRCm39)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,570,671 (GRCm39)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,479,551 (GRCm39)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,455,990 (GRCm39)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,449,302 (GRCm39)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,551,789 (GRCm39)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,631,008 (GRCm39)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,509,371 (GRCm39)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,556,413 (GRCm39)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,540,636 (GRCm39)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,591,469 (GRCm39)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,610,248 (GRCm39)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,531,570 (GRCm39)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,547,726 (GRCm39)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,514,659 (GRCm39)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,525,723 (GRCm39)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,649,530 (GRCm39)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,630,795 (GRCm39)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,692,870 (GRCm39)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,565,320 (GRCm39)	missense	probably benign	0.04
R9096:Hmcn1	UTSW	1	150,532,869 (GRCm39)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,573,331 (GRCm39)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,474,141 (GRCm39)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,506,092 (GRCm39)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,488,405 (GRCm39)	missense	probably damaging	1.00
R9182:Hmcn1	UTSW	1	150,500,337 (GRCm39)	nonsense	probably null
R9204:Hmcn1	UTSW	1	150,610,262 (GRCm39)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,594,844 (GRCm39)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,473,740 (GRCm39)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,506,046 (GRCm39)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,545,187 (GRCm39)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,506,053 (GRCm39)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,599,248 (GRCm39)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,506,471 (GRCm39)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,610,281 (GRCm39)	missense	probably benign	0.06
R9496:Hmcn1	UTSW	1	150,579,971 (GRCm39)	missense	probably benign	0.00
R9501:Hmcn1	UTSW	1	150,470,990 (GRCm39)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,545,175 (GRCm39)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,498,660 (GRCm39)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,475,303 (GRCm39)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,555,346 (GRCm39)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,684,473 (GRCm39)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,506,054 (GRCm39)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,619,492 (GRCm39)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,613,356 (GRCm39)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,485,378 (GRCm39)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,674,566 (GRCm39)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,623,941 (GRCm39)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,632,339 (GRCm39)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,868,625 (GRCm39)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,598,380 (GRCm39)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,528,333 (GRCm39)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,684,391 (GRCm39)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,500,312 (GRCm39)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,510,897 (GRCm39)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,576,281 (GRCm39)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,736,127 (GRCm39)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,539,652 (GRCm39)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,524,688 (GRCm39)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,539,668 (GRCm39)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,531,672 (GRCm39)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,462,196 (GRCm39)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- AGGCTTCAACCTATTTAAACTGACC -3'
(R):5'- CCATCCCTAGACAGGAATGGTC -3'

Sequencing Primer
(F):5'- GCAGGTGCTCTCTAAGTTATTTATAG -3'
(R):5'- CATCCCTAGACAGGAATGGTCAAAAG -3'

Posted On

2021-12-30