Incidental Mutation 'R9090:Magi3'
| ID |
690876 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R9090 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103923264 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1151
(D1151G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112934
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
[ENSMUST00000145727]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064371
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000121198
AA Change: D1151G
PolyPhen 2
Score 0.675 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: D1151G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122303
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145727
|
| SMART Domains |
Protein: ENSMUSP00000114722
Gene: ENSMUSG00000058388
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Phtf-FEM1B_bdg
|
3 |
158 |
1.6e-88 |
PFAM |
|
low complexity region
|
170 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
347 |
370 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
512 |
534 |
N/A |
INTRINSIC |
|
transmembrane domain
|
610 |
632 |
N/A |
INTRINSIC |
|
transmembrane domain
|
647 |
664 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
A |
T |
11: 119,901,940 (GRCm39) |
S819T |
probably damaging |
Het |
| Abca13 |
A |
T |
11: 9,241,698 (GRCm39) |
D1187V |
probably damaging |
Het |
| Ak9 |
C |
A |
10: 41,300,623 (GRCm39) |
T1611K |
unknown |
Het |
| Als2 |
G |
T |
1: 59,242,189 (GRCm39) |
T622K |
probably benign |
Het |
| Ankrd40 |
G |
A |
11: 94,225,262 (GRCm39) |
A98T |
probably benign |
Het |
| Ap1b1 |
T |
C |
11: 4,973,174 (GRCm39) |
L339P |
probably damaging |
Het |
| Appl1 |
A |
C |
14: 26,669,084 (GRCm39) |
H363Q |
probably benign |
Het |
| Atf6 |
T |
C |
1: 170,622,245 (GRCm39) |
N459D |
probably damaging |
Het |
| Ccdc6 |
A |
T |
10: 70,024,993 (GRCm39) |
Q432L |
unknown |
Het |
| Ccl21a |
T |
A |
4: 42,773,486 (GRCm39) |
Q84L |
probably damaging |
Het |
| Cct4 |
A |
G |
11: 22,951,389 (GRCm39) |
I348V |
probably benign |
Het |
| Cd300ld2 |
A |
G |
11: 114,904,550 (GRCm39) |
Y106H |
probably damaging |
Het |
| Cdh19 |
C |
T |
1: 110,876,947 (GRCm39) |
E131K |
probably damaging |
Het |
| Cdon |
A |
G |
9: 35,403,175 (GRCm39) |
D1095G |
probably damaging |
Het |
| Cep85l |
T |
A |
10: 53,157,670 (GRCm39) |
R678* |
probably null |
Het |
| Chst3 |
T |
A |
10: 60,021,465 (GRCm39) |
S461C |
probably damaging |
Het |
| Clk1 |
A |
G |
1: 58,459,312 (GRCm39) |
I149T |
possibly damaging |
Het |
| Clvs2 |
T |
A |
10: 33,389,301 (GRCm39) |
D313V |
possibly damaging |
Het |
| Dap3 |
T |
C |
3: 88,840,913 (GRCm39) |
T75A |
probably benign |
Het |
| Dnaaf1 |
T |
A |
8: 120,324,392 (GRCm39) |
F631L |
probably benign |
Het |
| Dnah14 |
A |
T |
1: 181,597,325 (GRCm39) |
N3549I |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,931,870 (GRCm39) |
Y3701N |
probably damaging |
Het |
| Dock6 |
A |
G |
9: 21,752,796 (GRCm39) |
V339A |
possibly damaging |
Het |
| Dpp6 |
T |
A |
5: 27,803,832 (GRCm39) |
C259* |
probably null |
Het |
| Dqx1 |
A |
G |
6: 83,036,024 (GRCm39) |
T119A |
probably benign |
Het |
| Dync1h1 |
G |
T |
12: 110,583,310 (GRCm39) |
R469L |
probably benign |
Het |
| Eno4 |
C |
T |
19: 58,951,260 (GRCm39) |
A424V |
probably benign |
Het |
| Entrep1 |
A |
T |
19: 23,972,221 (GRCm39) |
I161N |
possibly damaging |
Het |
| Fads1 |
T |
A |
19: 10,163,162 (GRCm39) |
D146E |
probably damaging |
Het |
| Fam171a1 |
C |
T |
2: 3,224,543 (GRCm39) |
T303M |
probably damaging |
Het |
| Fbxw20 |
C |
T |
9: 109,050,423 (GRCm39) |
D401N |
probably benign |
Het |
| Fcho1 |
T |
A |
8: 72,163,068 (GRCm39) |
T654S |
possibly damaging |
Het |
| Flad1 |
C |
A |
3: 89,315,858 (GRCm39) |
E235* |
probably null |
Het |
| Flrt2 |
G |
T |
12: 95,745,907 (GRCm39) |
A82S |
probably benign |
Het |
| Gabrg3 |
A |
T |
7: 56,829,386 (GRCm39) |
S124T |
probably benign |
Het |
| Galt |
C |
T |
4: 41,756,777 (GRCm39) |
T139I |
probably benign |
Het |
| Garin4 |
A |
G |
1: 190,895,153 (GRCm39) |
S497P |
probably damaging |
Het |
| Gfod1 |
T |
C |
13: 43,456,861 (GRCm39) |
E38G |
possibly damaging |
Het |
| Gm10330 |
A |
G |
12: 23,829,992 (GRCm39) |
I63T |
possibly damaging |
Het |
| Gm49359 |
A |
G |
13: 62,602,867 (GRCm39) |
V111A |
probably benign |
Het |
| Gpank1 |
C |
T |
17: 35,340,734 (GRCm39) |
|
probably benign |
Het |
| Hck |
T |
C |
2: 152,973,185 (GRCm39) |
L156P |
probably damaging |
Het |
| Hcn3 |
G |
T |
3: 89,057,267 (GRCm39) |
R444S |
probably damaging |
Het |
| Hephl1 |
T |
C |
9: 14,988,236 (GRCm39) |
N624S |
probably damaging |
Het |
| Hmcn1 |
A |
G |
1: 150,632,309 (GRCm39) |
I876T |
probably damaging |
Het |
| Ifi207 |
CTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATAGAGTTGCATATGGAGCCAGGAGGATGCTATATGTTGTTGATGAAGTTGCATGTGGAGCCAGGAG |
CTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATAGAGTTGCATATGGAGCCAGGAGGATGCTATATGTTGTTGATGAAGTTGCATGTGGAGCCAGGAG |
1: 173,556,762 (GRCm39) |
|
probably benign |
Het |
| Itga9 |
T |
A |
9: 118,500,859 (GRCm39) |
D377E |
possibly damaging |
Het |
| Itpr3 |
G |
A |
17: 27,337,651 (GRCm39) |
|
probably benign |
Het |
| Itprid1 |
G |
T |
6: 55,944,051 (GRCm39) |
R417L |
probably benign |
Het |
| Klk1b11 |
C |
T |
7: 43,425,954 (GRCm39) |
L32F |
probably benign |
Het |
| Lta4h |
A |
G |
10: 93,310,412 (GRCm39) |
S427G |
probably benign |
Het |
| Lxn |
T |
A |
3: 67,368,651 (GRCm39) |
I122F |
probably damaging |
Het |
| Lyz1 |
A |
G |
10: 117,124,492 (GRCm39) |
V148A |
possibly damaging |
Het |
| Mael |
G |
T |
1: 166,032,424 (GRCm39) |
Q326K |
probably benign |
Het |
| Map3k9 |
C |
A |
12: 81,769,261 (GRCm39) |
G929V |
probably benign |
Het |
| Mcoln1 |
A |
G |
8: 3,555,771 (GRCm39) |
Y22C |
probably damaging |
Het |
| Mier3 |
G |
T |
13: 111,827,870 (GRCm39) |
M45I |
probably benign |
Het |
| Mrpl1 |
T |
C |
5: 96,371,746 (GRCm39) |
V91A |
probably damaging |
Het |
| Myo7a |
T |
C |
7: 97,740,281 (GRCm39) |
H571R |
probably benign |
Het |
| Myom1 |
T |
A |
17: 71,374,325 (GRCm39) |
W601R |
probably damaging |
Het |
| Myom3 |
C |
T |
4: 135,505,479 (GRCm39) |
T456I |
probably benign |
Het |
| Nags |
A |
T |
11: 102,037,584 (GRCm39) |
H225L |
probably benign |
Het |
| Ncaph |
C |
A |
2: 126,958,554 (GRCm39) |
K488N |
probably damaging |
Het |
| Nkain3 |
C |
T |
4: 20,484,897 (GRCm39) |
R60H |
probably damaging |
Het |
| Nlrp9a |
A |
T |
7: 26,261,944 (GRCm39) |
M698L |
probably benign |
Het |
| Nmur2 |
A |
C |
11: 55,931,308 (GRCm39) |
I134M |
probably benign |
Het |
| Nrp2 |
A |
C |
1: 62,784,670 (GRCm39) |
E273A |
probably benign |
Het |
| Nup85 |
A |
G |
11: 115,468,787 (GRCm39) |
D210G |
possibly damaging |
Het |
| Obscn |
A |
G |
11: 59,006,643 (GRCm39) |
F1173S |
probably damaging |
Het |
| Or5ac24 |
A |
T |
16: 59,165,145 (GRCm39) |
C306* |
probably null |
Het |
| Otogl |
T |
A |
10: 107,652,974 (GRCm39) |
E1126V |
probably null |
Het |
| Pfkl |
T |
C |
10: 77,833,426 (GRCm39) |
I259V |
probably benign |
Het |
| Phkg1 |
A |
T |
5: 129,893,863 (GRCm39) |
Y291N |
probably benign |
Het |
| Piezo2 |
T |
G |
18: 63,163,450 (GRCm39) |
H2156P |
probably damaging |
Het |
| Piezo2 |
C |
A |
18: 63,208,790 (GRCm39) |
V1408L |
probably damaging |
Het |
| Pira13 |
T |
A |
7: 3,819,997 (GRCm39) |
E640V |
unknown |
Het |
| Plekhg3 |
A |
G |
12: 76,622,694 (GRCm39) |
T646A |
probably benign |
Het |
| Plk5 |
C |
G |
10: 80,193,830 (GRCm39) |
R40G |
probably damaging |
Het |
| Ppp1r12a |
T |
C |
10: 108,098,224 (GRCm39) |
S838P |
probably damaging |
Het |
| Rarb |
A |
T |
14: 16,435,235 (GRCm38) |
Y270* |
probably null |
Het |
| Rbm15 |
T |
C |
3: 107,239,312 (GRCm39) |
E362G |
possibly damaging |
Het |
| Rcan1 |
A |
G |
16: 92,262,741 (GRCm39) |
F76L |
|
Het |
| Rdh19 |
T |
C |
10: 127,696,142 (GRCm39) |
L298P |
probably damaging |
Het |
| Rims1 |
T |
A |
1: 22,498,773 (GRCm39) |
H57L |
|
Het |
| Rlf |
T |
C |
4: 121,004,751 (GRCm39) |
T1520A |
probably benign |
Het |
| Rnase1 |
T |
A |
14: 51,382,964 (GRCm39) |
H130L |
possibly damaging |
Het |
| Samd8 |
T |
A |
14: 21,842,569 (GRCm39) |
M360K |
probably damaging |
Het |
| Samhd1 |
A |
G |
2: 156,956,205 (GRCm39) |
L329P |
probably damaging |
Het |
| Scube1 |
C |
T |
15: 83,494,394 (GRCm39) |
E878K |
probably damaging |
Het |
| Sema3b |
T |
C |
9: 107,476,154 (GRCm39) |
Y689C |
probably damaging |
Het |
| Semp2l2a |
T |
C |
8: 13,886,697 (GRCm39) |
T465A |
possibly damaging |
Het |
| Sh3pxd2b |
A |
T |
11: 32,373,361 (GRCm39) |
N843Y |
possibly damaging |
Het |
| Slco1a6 |
C |
T |
6: 142,035,575 (GRCm39) |
C583Y |
probably damaging |
Het |
| Smg1 |
A |
C |
7: 117,811,786 (GRCm39) |
V88G |
unknown |
Het |
| Spata24 |
T |
A |
18: 35,790,054 (GRCm39) |
N146Y |
probably damaging |
Het |
| Tcf3 |
C |
A |
10: 80,253,191 (GRCm39) |
V258L |
probably benign |
Het |
| Tiam2 |
T |
C |
17: 3,465,011 (GRCm39) |
Y247H |
probably damaging |
Het |
| Ticrr |
T |
C |
7: 79,310,604 (GRCm39) |
F173L |
possibly damaging |
Het |
| Tpp2 |
A |
G |
1: 43,993,811 (GRCm39) |
E232G |
probably damaging |
Het |
| Trank1 |
T |
A |
9: 111,174,547 (GRCm39) |
V138E |
probably damaging |
Het |
| Ttll3 |
T |
C |
6: 113,369,596 (GRCm39) |
S47P |
probably benign |
Het |
| Utp4 |
C |
T |
8: 107,632,857 (GRCm39) |
T280M |
probably damaging |
Het |
| Vmn1r123 |
A |
T |
7: 20,896,794 (GRCm39) |
N229Y |
probably benign |
Het |
| Vmn1r85 |
A |
T |
7: 12,818,942 (GRCm39) |
Y67* |
probably null |
Het |
| Zbtb12 |
T |
A |
17: 35,114,320 (GRCm39) |
V35E |
possibly damaging |
Het |
| Zmym6 |
T |
A |
4: 127,017,854 (GRCm39) |
F1212I |
probably damaging |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0514:Magi3
|
UTSW |
3 |
103,922,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1964:Magi3
|
UTSW |
3 |
103,927,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2519:Magi3
|
UTSW |
3 |
103,923,081 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6244:Magi3
|
UTSW |
3 |
103,923,013 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Magi3
|
UTSW |
3 |
103,956,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7237:Magi3
|
UTSW |
3 |
103,935,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTCGACTCTTCTCGCCATG -3'
(R):5'- CTCCTCAGGCTATGCAACCAAG -3'
Sequencing Primer
(F):5'- TTCTCGCCATGCCCGGAAC -3'
(R):5'- GGCTGTCAGTTCAAAACTCACTG -3'
|
| Posted On |
2021-12-30 |
Incidental Mutation