Incidental Mutation 'R9154:Tanc1'
| ID |
695199 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc1
|
| Ensembl Gene |
ENSMUSG00000035168 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| Synonyms |
1200003E16Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9154 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
59442386-59676493 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 59630132 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 704
(L704P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123345
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037526]
[ENSMUST00000112568]
[ENSMUST00000139863]
|
| AlphaFold |
Q0VGY8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037526
AA Change: L704P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000036003
Gene: ENSMUSG00000035168
AA Change: L704P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112568
AA Change: L697P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108187
Gene: ENSMUSG00000035168
AA Change: L697P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
448 |
468 |
N/A |
INTRINSIC |
|
ANK
|
886 |
918 |
1.06e3 |
SMART |
|
ANK
|
922 |
953 |
2.43e3 |
SMART |
|
ANK
|
957 |
986 |
1.12e-3 |
SMART |
|
Blast:ANK
|
990 |
1021 |
7e-12 |
BLAST |
|
ANK
|
1030 |
1059 |
1.78e3 |
SMART |
|
ANK
|
1068 |
1097 |
2.34e-1 |
SMART |
|
ANK
|
1101 |
1130 |
3.71e-4 |
SMART |
|
ANK
|
1134 |
1163 |
1.51e-4 |
SMART |
|
ANK
|
1167 |
1196 |
4.89e-4 |
SMART |
|
ANK
|
1200 |
1229 |
3.01e-4 |
SMART |
|
ANK
|
1233 |
1262 |
1.99e2 |
SMART |
|
TPR
|
1279 |
1312 |
7.49e1 |
SMART |
|
TPR
|
1326 |
1359 |
2.35e-1 |
SMART |
|
TPR
|
1360 |
1393 |
6.29e-2 |
SMART |
|
low complexity region
|
1409 |
1425 |
N/A |
INTRINSIC |
|
low complexity region
|
1447 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1679 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000139863
AA Change: L704P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000123345
Gene: ENSMUSG00000035168
AA Change: L704P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930590J08Rik |
T |
C |
6: 91,926,926 (GRCm39) |
V862A |
probably benign |
Het |
| A2m |
A |
T |
6: 121,645,512 (GRCm39) |
K1019M |
probably damaging |
Het |
| Acot6 |
G |
T |
12: 84,147,789 (GRCm39) |
W15L |
possibly damaging |
Het |
| Adam32 |
CCAGCAGCAGCAGCAGCAG |
CCAGCAGCAGCAGCAG |
8: 25,438,769 (GRCm39) |
|
probably benign |
Het |
| Adnp |
C |
A |
2: 168,026,580 (GRCm39) |
Q238H |
possibly damaging |
Het |
| Akap7 |
T |
C |
10: 25,047,053 (GRCm39) |
Y281C |
probably damaging |
Het |
| Ank1 |
A |
G |
8: 23,605,387 (GRCm39) |
E1085G |
probably damaging |
Het |
| Arhgef38 |
A |
T |
3: 132,837,924 (GRCm39) |
S669T |
unknown |
Het |
| Atp8b2 |
A |
T |
3: 89,865,927 (GRCm39) |
S50R |
possibly damaging |
Het |
| Atp8b5 |
T |
C |
4: 43,372,630 (GRCm39) |
I1090T |
probably benign |
Het |
| Ccdc198 |
A |
T |
14: 49,473,367 (GRCm39) |
H129Q |
probably benign |
Het |
| Chrna4 |
G |
A |
2: 180,670,602 (GRCm39) |
R385C |
probably damaging |
Het |
| Col4a1 |
T |
A |
8: 11,267,446 (GRCm39) |
I1105F |
probably damaging |
Het |
| Crybg2 |
G |
A |
4: 133,792,620 (GRCm39) |
R85Q |
probably benign |
Het |
| Cspg4 |
T |
A |
9: 56,798,287 (GRCm39) |
L1434Q |
|
Het |
| Cyp3a13 |
T |
C |
5: 137,919,758 (GRCm39) |
N6S |
probably benign |
Het |
| Dnase2b |
A |
T |
3: 146,299,326 (GRCm39) |
Y42* |
probably null |
Het |
| F11r |
A |
G |
1: 171,289,376 (GRCm39) |
E233G |
probably damaging |
Het |
| Fip1l1 |
T |
C |
5: 74,747,703 (GRCm39) |
I390T |
possibly damaging |
Het |
| Fiz1 |
G |
A |
7: 5,011,280 (GRCm39) |
R413C |
probably damaging |
Het |
| Fus |
G |
A |
7: 127,580,440 (GRCm39) |
G450E |
unknown |
Het |
| Gm11569 |
C |
A |
11: 99,689,267 (GRCm39) |
C144F |
unknown |
Het |
| Gm7298 |
A |
T |
6: 121,756,436 (GRCm39) |
Y1027F |
probably damaging |
Het |
| Grik5 |
C |
A |
7: 24,758,403 (GRCm39) |
W340L |
probably damaging |
Het |
| H1f2 |
A |
G |
13: 23,923,373 (GRCm39) |
K181R |
unknown |
Het |
| Hectd4 |
G |
A |
5: 121,391,967 (GRCm39) |
R77H |
|
Het |
| Ift81 |
C |
A |
5: 122,689,122 (GRCm39) |
V665L |
probably benign |
Het |
| Ints2 |
A |
G |
11: 86,125,524 (GRCm39) |
F559L |
probably damaging |
Het |
| Kdm8 |
G |
A |
7: 125,054,296 (GRCm39) |
V176I |
probably benign |
Het |
| Keap1 |
A |
T |
9: 21,142,121 (GRCm39) |
Y584* |
probably null |
Het |
| Klra1 |
T |
C |
6: 130,357,607 (GRCm39) |
T7A |
|
Het |
| Lmo7 |
T |
A |
14: 102,122,743 (GRCm39) |
W311R |
probably damaging |
Het |
| Lrp6 |
A |
G |
6: 134,518,855 (GRCm39) |
V70A |
probably damaging |
Het |
| Luc7l3 |
A |
T |
11: 94,190,793 (GRCm39) |
S174T |
unknown |
Het |
| Madd |
T |
C |
2: 90,998,162 (GRCm39) |
T653A |
probably damaging |
Het |
| Mlph |
G |
T |
1: 90,855,716 (GRCm39) |
G41V |
probably damaging |
Het |
| Mov10l1 |
A |
G |
15: 88,896,118 (GRCm39) |
E654G |
possibly damaging |
Het |
| Mpp3 |
T |
C |
11: 101,911,328 (GRCm39) |
I165V |
|
Het |
| Mrgpra2a |
T |
G |
7: 47,076,394 (GRCm39) |
Y288S |
probably damaging |
Het |
| Mroh9 |
T |
A |
1: 162,890,030 (GRCm39) |
M236L |
|
Het |
| Muc5b |
A |
C |
7: 141,417,974 (GRCm39) |
K3640T |
probably damaging |
Het |
| Myh13 |
A |
G |
11: 67,253,318 (GRCm39) |
I1485V |
probably benign |
Het |
| Nf2 |
A |
T |
11: 4,744,873 (GRCm39) |
F285L |
probably damaging |
Het |
| Nfx1 |
T |
A |
4: 40,990,845 (GRCm39) |
C471S |
probably damaging |
Het |
| Nsd1 |
C |
T |
13: 55,361,253 (GRCm39) |
R74W |
probably damaging |
Het |
| Nudt16l1 |
A |
T |
16: 4,758,281 (GRCm39) |
*212C |
probably null |
Het |
| Oaf |
T |
C |
9: 43,133,992 (GRCm39) |
Y243C |
probably damaging |
Het |
| Or51e1 |
T |
C |
7: 102,358,541 (GRCm39) |
V25A |
probably benign |
Het |
| Or6c3 |
T |
C |
10: 129,308,690 (GRCm39) |
I43T |
probably benign |
Het |
| Or7g30 |
T |
A |
9: 19,352,531 (GRCm39) |
F107L |
probably benign |
Het |
| Or7h8 |
A |
G |
9: 20,124,173 (GRCm39) |
H176R |
possibly damaging |
Het |
| Or8b36 |
T |
A |
9: 37,937,690 (GRCm39) |
L196* |
probably null |
Het |
| Parp9 |
T |
C |
16: 35,768,543 (GRCm39) |
I241T |
probably damaging |
Het |
| Phlpp2 |
G |
T |
8: 110,666,590 (GRCm39) |
A1040S |
possibly damaging |
Het |
| Pon2 |
A |
T |
6: 5,265,391 (GRCm39) |
V332E |
possibly damaging |
Het |
| Ptprc |
A |
G |
1: 138,016,302 (GRCm39) |
V544A |
probably damaging |
Het |
| Rfx6 |
A |
G |
10: 51,597,600 (GRCm39) |
S446G |
probably benign |
Het |
| Rnf103 |
T |
A |
6: 71,487,099 (GRCm39) |
C577S |
probably benign |
Het |
| Ros1 |
T |
G |
10: 51,922,301 (GRCm39) |
E2278D |
possibly damaging |
Het |
| Rpl37 |
A |
G |
15: 5,147,109 (GRCm39) |
S50G |
probably benign |
Het |
| Rrad |
C |
T |
8: 105,355,343 (GRCm39) |
V222M |
possibly damaging |
Het |
| Ryr1 |
T |
C |
7: 28,769,283 (GRCm39) |
T2770A |
probably benign |
Het |
| Secisbp2l |
G |
A |
2: 125,617,623 (GRCm39) |
P18L |
probably damaging |
Het |
| Septin2 |
T |
A |
1: 93,429,310 (GRCm39) |
W260R |
probably damaging |
Het |
| Slc35c2 |
A |
G |
2: 165,122,797 (GRCm39) |
M117T |
probably benign |
Het |
| Slc44a5 |
A |
G |
3: 153,953,373 (GRCm39) |
T252A |
probably benign |
Het |
| Speer4f2 |
T |
A |
5: 17,581,610 (GRCm39) |
L184Q |
|
Het |
| Sphkap |
C |
G |
1: 83,234,982 (GRCm39) |
V1615L |
probably damaging |
Het |
| Sult2a3 |
C |
T |
7: 13,806,981 (GRCm39) |
V234I |
probably benign |
Het |
| Tas2r126 |
T |
C |
6: 42,412,174 (GRCm39) |
S236P |
probably benign |
Het |
| Tnik |
A |
G |
3: 28,704,235 (GRCm39) |
I1020V |
probably damaging |
Het |
| Tomm5 |
T |
C |
4: 45,106,724 (GRCm39) |
Q64R |
unknown |
Het |
| Ttll13 |
A |
G |
7: 79,897,182 (GRCm39) |
E16G |
probably benign |
Het |
| Vmn1r21 |
C |
A |
6: 57,821,348 (GRCm39) |
C32F |
probably benign |
Het |
| Vmn2r51 |
T |
A |
7: 9,839,480 (GRCm39) |
D36V |
probably damaging |
Het |
| Vmn2r63 |
C |
T |
7: 42,576,413 (GRCm39) |
D467N |
probably damaging |
Het |
| Vwce |
A |
G |
19: 10,625,850 (GRCm39) |
N454S |
possibly damaging |
Het |
| Wfdc1 |
A |
C |
8: 120,406,116 (GRCm39) |
D77A |
|
Het |
| Yme1l1 |
T |
A |
2: 23,077,815 (GRCm39) |
I419N |
probably damaging |
Het |
| Zfp106 |
G |
A |
2: 120,364,812 (GRCm39) |
Q555* |
probably null |
Het |
| Zfp773 |
A |
C |
7: 7,138,302 (GRCm39) |
M111R |
probably damaging |
Het |
| Zmat3 |
G |
A |
3: 32,397,767 (GRCm39) |
A165V |
possibly damaging |
Het |
|
| Other mutations in Tanc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Tanc1
|
APN |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL00484:Tanc1
|
APN |
2 |
59,623,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00688:Tanc1
|
APN |
2 |
59,645,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00765:Tanc1
|
APN |
2 |
59,636,645 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01576:Tanc1
|
APN |
2 |
59,628,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01590:Tanc1
|
APN |
2 |
59,615,817 (GRCm39) |
missense |
probably benign |
|
|
IGL02016:Tanc1
|
APN |
2 |
59,673,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02373:Tanc1
|
APN |
2 |
59,626,372 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02539:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02541:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Tanc1
|
APN |
2 |
59,554,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL02626:Tanc1
|
APN |
2 |
59,630,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02669:Tanc1
|
APN |
2 |
59,630,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Tanc1
|
APN |
2 |
59,623,431 (GRCm39) |
splice site |
probably benign |
|
|
Oreja
|
UTSW |
2 |
59,622,148 (GRCm39) |
synonymous |
silent |
|
|
R0178:Tanc1
|
UTSW |
2 |
59,665,791 (GRCm39) |
nonsense |
probably null |
|
|
R0347:Tanc1
|
UTSW |
2 |
59,673,335 (GRCm39) |
missense |
probably benign |
|
|
R0570:Tanc1
|
UTSW |
2 |
59,626,382 (GRCm39) |
splice site |
probably benign |
|
|
R0660:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0664:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0898:Tanc1
|
UTSW |
2 |
59,621,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1333:Tanc1
|
UTSW |
2 |
59,673,835 (GRCm39) |
missense |
probably benign |
|
|
R1575:Tanc1
|
UTSW |
2 |
59,621,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1608:Tanc1
|
UTSW |
2 |
59,628,038 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1616:Tanc1
|
UTSW |
2 |
59,615,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1703:Tanc1
|
UTSW |
2 |
59,673,365 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1727:Tanc1
|
UTSW |
2 |
59,621,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Tanc1
|
UTSW |
2 |
59,630,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1812:Tanc1
|
UTSW |
2 |
59,622,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1925:Tanc1
|
UTSW |
2 |
59,555,095 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1951:Tanc1
|
UTSW |
2 |
59,622,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Tanc1
|
UTSW |
2 |
59,674,177 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2228:Tanc1
|
UTSW |
2 |
59,555,068 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2267:Tanc1
|
UTSW |
2 |
59,667,563 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4191:Tanc1
|
UTSW |
2 |
59,669,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4476:Tanc1
|
UTSW |
2 |
59,672,340 (GRCm39) |
splice site |
probably null |
|
|
R4632:Tanc1
|
UTSW |
2 |
59,626,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Tanc1
|
UTSW |
2 |
59,529,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4982:Tanc1
|
UTSW |
2 |
59,630,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5338:Tanc1
|
UTSW |
2 |
59,626,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5657:Tanc1
|
UTSW |
2 |
59,665,051 (GRCm39) |
splice site |
probably null |
|
|
R5672:Tanc1
|
UTSW |
2 |
59,602,697 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5703:Tanc1
|
UTSW |
2 |
59,626,341 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5707:Tanc1
|
UTSW |
2 |
59,588,874 (GRCm39) |
missense |
probably benign |
|
|
R5778:Tanc1
|
UTSW |
2 |
59,529,691 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5795:Tanc1
|
UTSW |
2 |
59,637,926 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5831:Tanc1
|
UTSW |
2 |
59,615,685 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5849:Tanc1
|
UTSW |
2 |
59,630,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5912:Tanc1
|
UTSW |
2 |
59,622,030 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5944:Tanc1
|
UTSW |
2 |
59,667,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6057:Tanc1
|
UTSW |
2 |
59,647,837 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6142:Tanc1
|
UTSW |
2 |
59,663,566 (GRCm39) |
nonsense |
probably null |
|
|
R6179:Tanc1
|
UTSW |
2 |
59,673,320 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6185:Tanc1
|
UTSW |
2 |
59,621,929 (GRCm39) |
splice site |
probably null |
|
|
R6192:Tanc1
|
UTSW |
2 |
59,669,305 (GRCm39) |
splice site |
probably null |
|
|
R6196:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6197:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6230:Tanc1
|
UTSW |
2 |
59,672,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6275:Tanc1
|
UTSW |
2 |
59,673,854 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6415:Tanc1
|
UTSW |
2 |
59,667,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6480:Tanc1
|
UTSW |
2 |
59,637,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6578:Tanc1
|
UTSW |
2 |
59,626,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Tanc1
|
UTSW |
2 |
59,622,150 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7006:Tanc1
|
UTSW |
2 |
59,626,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Tanc1
|
UTSW |
2 |
59,627,953 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7381:Tanc1
|
UTSW |
2 |
59,615,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Tanc1
|
UTSW |
2 |
59,636,688 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8392:Tanc1
|
UTSW |
2 |
59,636,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8692:Tanc1
|
UTSW |
2 |
59,673,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8730:Tanc1
|
UTSW |
2 |
59,601,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8731:Tanc1
|
UTSW |
2 |
59,673,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8813:Tanc1
|
UTSW |
2 |
59,630,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8815:Tanc1
|
UTSW |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8933:Tanc1
|
UTSW |
2 |
59,615,800 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9015:Tanc1
|
UTSW |
2 |
59,622,224 (GRCm39) |
missense |
probably benign |
|
|
R9042:Tanc1
|
UTSW |
2 |
59,673,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9269:Tanc1
|
UTSW |
2 |
59,630,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Tanc1
|
UTSW |
2 |
59,630,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9380:Tanc1
|
UTSW |
2 |
59,665,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tanc1
|
UTSW |
2 |
59,637,933 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9428:Tanc1
|
UTSW |
2 |
59,601,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Tanc1
|
UTSW |
2 |
59,626,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF028:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
RF049:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Tanc1
|
UTSW |
2 |
59,674,324 (GRCm39) |
nonsense |
probably null |
|
|
X0064:Tanc1
|
UTSW |
2 |
59,674,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tanc1
|
UTSW |
2 |
59,602,873 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,622,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,621,231 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGCACTGCCATTTGTCAAGC -3'
(R):5'- ATATCTGCTCATCCGTCATGGGG -3'
Sequencing Primer
(F):5'- GTCAAGCTTTCCCTAGACGAC -3'
(R):5'- CTCATCCGTCATGGGGTGGAG -3'
|
| Posted On |
2022-01-20 |
Incidental Mutation