Incidental Mutation 'R9169:Adamtsl3'
| ID |
696263 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamtsl3
|
| Ensembl Gene |
ENSMUSG00000070469 |
| Gene Name |
ADAMTS-like 3 |
| Synonyms |
9230119C12Rik, punctin-2 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9169 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
81984902-82263658 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 82223188 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Leucine
at position 990
(I990L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133637
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173287]
[ENSMUST00000173828]
|
| AlphaFold |
G3UXC7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000173287
AA Change: I990L
PolyPhen 2
Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000133637
Gene: ENSMUSG00000070469
AA Change: I990L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
38 |
N/A |
INTRINSIC |
|
TSP1
|
90 |
136 |
6.43e-8 |
SMART |
|
TSP1
|
355 |
414 |
1.59e-1 |
SMART |
|
TSP1
|
433 |
492 |
3.72e-4 |
SMART |
|
TSP1
|
494 |
547 |
4.28e-4 |
SMART |
|
TSP1
|
579 |
638 |
1.85e-2 |
SMART |
|
TSP1
|
660 |
717 |
1.75e-2 |
SMART |
|
TSP1
|
719 |
773 |
3.45e-8 |
SMART |
|
TSP1
|
775 |
833 |
3.67e-3 |
SMART |
|
TSP1
|
836 |
894 |
8.99e-2 |
SMART |
|
IGc2
|
938 |
1002 |
7.59e-4 |
SMART |
|
IG
|
1213 |
1296 |
4.87e0 |
SMART |
|
IGc2
|
1326 |
1388 |
1.01e-13 |
SMART |
|
TSP1
|
1441 |
1498 |
1.95e-2 |
SMART |
|
TSP1
|
1500 |
1559 |
6.76e-2 |
SMART |
|
TSP1
|
1616 |
1666 |
3.84e-1 |
SMART |
|
Pfam:PLAC
|
1674 |
1704 |
2.4e-11 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000133337
Gene: ENSMUSG00000070469
AA Change: I64L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
Blast:IG
|
22 |
79 |
1e-26 |
BLAST |
|
SCOP:d1biha4
|
27 |
77 |
2e-5 |
SMART |
|
IG
|
283 |
366 |
4.87e0 |
SMART |
|
IGc2
|
396 |
458 |
1.01e-13 |
SMART |
|
TSP1
|
511 |
568 |
1.95e-2 |
SMART |
|
TSP1
|
570 |
629 |
6.76e-2 |
SMART |
|
TSP1
|
686 |
736 |
3.84e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (92/92) |
| Allele List at MGI |
All alleles(10) : Targeted(7) Gene trapped(2) Spontaneous(1)
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
A |
T |
7: 41,261,109 (GRCm39) |
|
probably benign |
Het |
| 9330182O14Rik |
A |
T |
15: 40,005,632 (GRCm39) |
K17* |
probably null |
Het |
| Add1 |
T |
A |
5: 34,788,122 (GRCm39) |
S724T |
possibly damaging |
Het |
| Afdn |
A |
G |
17: 14,072,627 (GRCm39) |
N865S |
probably benign |
Het |
| Amot |
A |
T |
X: 144,244,745 (GRCm39) |
L435H |
|
Het |
| Ap1m2 |
T |
A |
9: 21,223,523 (GRCm39) |
I8F |
probably benign |
Het |
| Atp8a1 |
T |
C |
5: 67,824,944 (GRCm39) |
T811A |
|
Het |
| Axin2 |
A |
G |
11: 108,822,378 (GRCm39) |
D310G |
probably damaging |
Het |
| Bin1 |
T |
G |
18: 32,562,251 (GRCm39) |
F379L |
possibly damaging |
Het |
| Bin2 |
C |
A |
15: 100,554,631 (GRCm39) |
S91I |
possibly damaging |
Het |
| Birc5 |
A |
G |
11: 117,743,599 (GRCm39) |
N111S |
probably benign |
Het |
| Blk |
T |
A |
14: 63,620,130 (GRCm39) |
N137Y |
probably damaging |
Het |
| Cacna1d |
G |
A |
14: 29,796,873 (GRCm39) |
A1534V |
probably damaging |
Het |
| Cacna2d1 |
T |
C |
5: 16,451,757 (GRCm39) |
V207A |
probably damaging |
Het |
| Ccr3 |
A |
G |
9: 123,828,949 (GRCm39) |
I95V |
probably benign |
Het |
| Celsr2 |
T |
C |
3: 108,309,862 (GRCm39) |
D1579G |
probably benign |
Het |
| Cfap36 |
C |
A |
11: 29,196,541 (GRCm39) |
K19N |
probably benign |
Het |
| Cfap52 |
C |
T |
11: 67,844,860 (GRCm39) |
V70M |
possibly damaging |
Het |
| Chid1 |
A |
T |
7: 141,093,722 (GRCm39) |
I298N |
probably damaging |
Het |
| Clstn1 |
G |
T |
4: 149,731,322 (GRCm39) |
R888L |
possibly damaging |
Het |
| Col6a5 |
T |
A |
9: 105,822,596 (GRCm39) |
T254S |
unknown |
Het |
| Coro6 |
C |
T |
11: 77,359,329 (GRCm39) |
P301S |
probably damaging |
Het |
| Cstdc2 |
A |
G |
2: 148,692,589 (GRCm39) |
|
probably null |
Het |
| Dchs1 |
T |
C |
7: 105,422,114 (GRCm39) |
D102G |
probably damaging |
Het |
| Dnah14 |
T |
C |
1: 181,433,381 (GRCm39) |
F353L |
probably benign |
Het |
| Dnajc10 |
A |
T |
2: 80,163,315 (GRCm39) |
I344L |
probably benign |
Het |
| Dst |
T |
C |
1: 34,303,652 (GRCm39) |
V4026A |
probably damaging |
Het |
| Exo1 |
A |
G |
1: 175,715,203 (GRCm39) |
E114G |
possibly damaging |
Het |
| Fabp7 |
A |
G |
10: 57,662,439 (GRCm39) |
I109V |
probably benign |
Het |
| Fars2 |
T |
C |
13: 36,416,109 (GRCm39) |
F206S |
probably damaging |
Het |
| Gbp8 |
C |
T |
5: 105,179,155 (GRCm39) |
A115T |
possibly damaging |
Het |
| Gm17067 |
T |
C |
7: 42,357,627 (GRCm39) |
T292A |
probably benign |
Het |
| Gp2 |
T |
C |
7: 119,041,929 (GRCm39) |
D532G |
probably benign |
Het |
| Gtf2i |
C |
A |
5: 134,271,534 (GRCm39) |
A917S |
probably damaging |
Het |
| Guca1b |
A |
G |
17: 47,702,827 (GRCm39) |
E169G |
possibly damaging |
Het |
| Hdac1 |
A |
T |
4: 129,428,499 (GRCm39) |
Y24N |
probably damaging |
Het |
| Hepacam |
T |
C |
9: 37,293,693 (GRCm39) |
F251L |
probably damaging |
Het |
| Hmcn1 |
G |
T |
1: 150,506,092 (GRCm39) |
N3811K |
probably damaging |
Het |
| Htra4 |
A |
T |
8: 25,520,133 (GRCm39) |
M391K |
probably damaging |
Het |
| Ino80d |
T |
C |
1: 63,097,930 (GRCm39) |
T760A |
probably benign |
Het |
| Ints1 |
T |
G |
5: 139,748,586 (GRCm39) |
T1074P |
probably benign |
Het |
| Itga6 |
A |
T |
2: 71,647,015 (GRCm39) |
Q75L |
possibly damaging |
Het |
| Mapk14 |
A |
C |
17: 28,960,814 (GRCm39) |
N272T |
probably benign |
Het |
| Meikin |
A |
T |
11: 54,285,517 (GRCm39) |
T185S |
possibly damaging |
Het |
| Moxd2 |
C |
T |
6: 40,860,490 (GRCm39) |
G318D |
possibly damaging |
Het |
| Mtmr3 |
G |
A |
11: 4,437,739 (GRCm39) |
T905I |
probably benign |
Het |
| Muc16 |
A |
G |
9: 18,567,824 (GRCm39) |
I1565T |
unknown |
Het |
| Myh14 |
A |
G |
7: 44,271,281 (GRCm39) |
S1500P |
possibly damaging |
Het |
| Nfkb1 |
T |
C |
3: 135,310,874 (GRCm39) |
E475G |
probably benign |
Het |
| Ngef |
C |
A |
1: 87,473,581 (GRCm39) |
R67L |
probably benign |
Het |
| Olr1 |
T |
C |
6: 129,470,528 (GRCm39) |
E213G |
probably damaging |
Het |
| Or13c3 |
T |
A |
4: 52,856,052 (GRCm39) |
I154F |
probably damaging |
Het |
| Or5b124 |
A |
G |
19: 13,610,903 (GRCm39) |
I143V |
probably benign |
Het |
| Or8g21 |
A |
G |
9: 38,906,573 (GRCm39) |
S53P |
probably benign |
Het |
| Or9r3 |
A |
C |
10: 129,947,723 (GRCm39) |
I312R |
probably benign |
Het |
| Pcdhga3 |
C |
T |
18: 37,809,088 (GRCm39) |
L514F |
probably damaging |
Het |
| Pcnt |
A |
G |
10: 76,221,572 (GRCm39) |
M2018T |
possibly damaging |
Het |
| Pde8a |
C |
T |
7: 80,982,619 (GRCm39) |
T746I |
probably damaging |
Het |
| Pik3ca |
T |
C |
3: 32,503,755 (GRCm39) |
|
probably null |
Het |
| Psapl1 |
A |
G |
5: 36,362,880 (GRCm39) |
S491G |
possibly damaging |
Het |
| Psmf1 |
A |
T |
2: 151,577,457 (GRCm39) |
D73E |
probably benign |
Het |
| Ptprcap |
A |
G |
19: 4,206,358 (GRCm39) |
D147G |
probably benign |
Het |
| Ramacl |
T |
C |
13: 67,056,063 (GRCm39) |
F19L |
probably damaging |
Het |
| Rdh8 |
T |
A |
9: 20,736,935 (GRCm39) |
V309E |
possibly damaging |
Het |
| Rhobtb3 |
T |
A |
13: 76,041,121 (GRCm39) |
T396S |
probably benign |
Het |
| Rpa1 |
A |
T |
11: 75,200,999 (GRCm39) |
L475* |
probably null |
Het |
| Rtkn |
T |
A |
6: 83,129,190 (GRCm39) |
S562T |
probably damaging |
Het |
| Saxo5 |
A |
T |
8: 3,525,967 (GRCm39) |
Y40F |
possibly damaging |
Het |
| Scamp1 |
C |
T |
13: 94,389,533 (GRCm39) |
D35N |
probably benign |
Het |
| Scarb1 |
C |
T |
5: 125,371,146 (GRCm39) |
A309T |
probably damaging |
Het |
| Scube1 |
G |
A |
15: 83,543,298 (GRCm39) |
T180M |
possibly damaging |
Het |
| Sez6 |
T |
G |
11: 77,868,473 (GRCm39) |
F945V |
probably damaging |
Het |
| Sf3a1 |
C |
T |
11: 4,116,681 (GRCm39) |
T124M |
probably benign |
Het |
| Smchd1 |
T |
C |
17: 71,722,659 (GRCm39) |
K759E |
probably damaging |
Het |
| Sort1 |
C |
A |
3: 108,247,994 (GRCm39) |
C446* |
probably null |
Het |
| Sun1 |
T |
A |
5: 139,219,273 (GRCm39) |
S360T |
probably benign |
Het |
| Supv3l1 |
A |
G |
10: 62,268,238 (GRCm39) |
F536L |
probably damaging |
Het |
| Taar6 |
A |
C |
10: 23,861,273 (GRCm39) |
V91G |
probably damaging |
Het |
| Themis |
C |
A |
10: 28,658,233 (GRCm39) |
T420N |
probably benign |
Het |
| Thoc2l |
T |
A |
5: 104,666,348 (GRCm39) |
L290H |
probably damaging |
Het |
| Tmc2 |
T |
A |
2: 130,083,516 (GRCm39) |
I491N |
probably damaging |
Het |
| Trmt112 |
T |
C |
19: 6,888,187 (GRCm39) |
I113T |
probably damaging |
Het |
| Ttc14 |
C |
T |
3: 33,857,071 (GRCm39) |
Q183* |
probably null |
Het |
| Txndc16 |
T |
A |
14: 45,373,385 (GRCm39) |
D748V |
probably damaging |
Het |
| Xkr6 |
A |
G |
14: 63,844,067 (GRCm39) |
D30G |
possibly damaging |
Het |
| Zc3h14 |
C |
T |
12: 98,745,505 (GRCm39) |
S498L |
probably damaging |
Het |
| Zc3h7b |
A |
C |
15: 81,661,184 (GRCm39) |
D341A |
probably benign |
Het |
| Zfp108 |
T |
A |
7: 23,960,923 (GRCm39) |
C505S |
probably damaging |
Het |
| Zfp354c |
A |
C |
11: 50,706,088 (GRCm39) |
L329R |
probably damaging |
Het |
| Zfyve16 |
T |
A |
13: 92,657,871 (GRCm39) |
D680V |
probably damaging |
Het |
| Znfx1 |
A |
G |
2: 166,897,185 (GRCm39) |
F580L |
probably benign |
Het |
|
| Other mutations in Adamtsl3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01549:Adamtsl3
|
APN |
7 |
82,261,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01936:Adamtsl3
|
APN |
7 |
82,244,579 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02819:Adamtsl3
|
APN |
7 |
82,223,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0012:Adamtsl3
|
UTSW |
7 |
82,223,465 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0180:Adamtsl3
|
UTSW |
7 |
82,225,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Adamtsl3
|
UTSW |
7 |
82,206,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Adamtsl3
|
UTSW |
7 |
82,197,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0329:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0330:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0548:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0611:Adamtsl3
|
UTSW |
7 |
82,178,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0671:Adamtsl3
|
UTSW |
7 |
82,172,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0845:Adamtsl3
|
UTSW |
7 |
82,225,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1119:Adamtsl3
|
UTSW |
7 |
82,189,525 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1458:Adamtsl3
|
UTSW |
7 |
82,172,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Adamtsl3
|
UTSW |
7 |
82,099,298 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1691:Adamtsl3
|
UTSW |
7 |
82,148,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Adamtsl3
|
UTSW |
7 |
82,142,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Adamtsl3
|
UTSW |
7 |
82,227,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2245:Adamtsl3
|
UTSW |
7 |
82,099,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2274:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2275:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2448:Adamtsl3
|
UTSW |
7 |
82,148,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3725:Adamtsl3
|
UTSW |
7 |
82,261,612 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R3757:Adamtsl3
|
UTSW |
7 |
81,986,415 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3821:Adamtsl3
|
UTSW |
7 |
82,255,687 (GRCm39) |
splice site |
probably benign |
|
|
R4618:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4842:Adamtsl3
|
UTSW |
7 |
82,178,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4888:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4925:Adamtsl3
|
UTSW |
7 |
82,251,507 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4960:Adamtsl3
|
UTSW |
7 |
82,216,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5026:Adamtsl3
|
UTSW |
7 |
82,225,262 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5152:Adamtsl3
|
UTSW |
7 |
82,223,752 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5198:Adamtsl3
|
UTSW |
7 |
82,261,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5244:Adamtsl3
|
UTSW |
7 |
82,247,277 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5281:Adamtsl3
|
UTSW |
7 |
82,178,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5323:Adamtsl3
|
UTSW |
7 |
82,206,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5523:Adamtsl3
|
UTSW |
7 |
82,223,650 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5602:Adamtsl3
|
UTSW |
7 |
82,206,447 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5638:Adamtsl3
|
UTSW |
7 |
82,260,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5682:Adamtsl3
|
UTSW |
7 |
82,255,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5782:Adamtsl3
|
UTSW |
7 |
82,189,494 (GRCm39) |
splice site |
probably null |
|
|
R5946:Adamtsl3
|
UTSW |
7 |
82,225,265 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6091:Adamtsl3
|
UTSW |
7 |
82,114,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6500:Adamtsl3
|
UTSW |
7 |
82,227,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6765:Adamtsl3
|
UTSW |
7 |
82,216,232 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6785:Adamtsl3
|
UTSW |
7 |
82,171,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6982:Adamtsl3
|
UTSW |
7 |
82,164,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R7341:Adamtsl3
|
UTSW |
7 |
82,206,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Adamtsl3
|
UTSW |
7 |
82,227,825 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7506:Adamtsl3
|
UTSW |
7 |
82,164,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7549:Adamtsl3
|
UTSW |
7 |
82,223,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7575:Adamtsl3
|
UTSW |
7 |
82,223,756 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7592:Adamtsl3
|
UTSW |
7 |
81,986,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7617:Adamtsl3
|
UTSW |
7 |
82,206,054 (GRCm39) |
splice site |
probably null |
|
|
R7654:Adamtsl3
|
UTSW |
7 |
82,223,702 (GRCm39) |
missense |
probably benign |
|
|
R7721:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7784:Adamtsl3
|
UTSW |
7 |
82,223,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7858:Adamtsl3
|
UTSW |
7 |
82,099,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8109:Adamtsl3
|
UTSW |
7 |
82,251,487 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8125:Adamtsl3
|
UTSW |
7 |
82,099,541 (GRCm39) |
splice site |
probably null |
|
|
R8211:Adamtsl3
|
UTSW |
7 |
82,172,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8348:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8360:Adamtsl3
|
UTSW |
7 |
82,197,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8448:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8465:Adamtsl3
|
UTSW |
7 |
82,247,330 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8547:Adamtsl3
|
UTSW |
7 |
82,077,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8551:Adamtsl3
|
UTSW |
7 |
82,189,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8558:Adamtsl3
|
UTSW |
7 |
82,077,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8709:Adamtsl3
|
UTSW |
7 |
82,077,642 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8722:Adamtsl3
|
UTSW |
7 |
82,244,745 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8930:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R8932:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R9131:Adamtsl3
|
UTSW |
7 |
82,244,722 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9272:Adamtsl3
|
UTSW |
7 |
82,189,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9276:Adamtsl3
|
UTSW |
7 |
82,206,710 (GRCm39) |
intron |
probably benign |
|
|
R9351:Adamtsl3
|
UTSW |
7 |
82,169,929 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9352:Adamtsl3
|
UTSW |
7 |
82,091,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9749:Adamtsl3
|
UTSW |
7 |
82,099,394 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9750:Adamtsl3
|
UTSW |
7 |
82,244,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
RF005:Adamtsl3
|
UTSW |
7 |
82,261,603 (GRCm39) |
missense |
|
|
|
X0003:Adamtsl3
|
UTSW |
7 |
82,260,967 (GRCm39) |
nonsense |
probably null |
|
|
X0063:Adamtsl3
|
UTSW |
7 |
82,223,365 (GRCm39) |
missense |
probably benign |
0.25 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,189,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,148,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGTAGAGCCTACTTGCTGC -3'
(R):5'- AAGGCTGCTTATTCATTTCACCAC -3'
Sequencing Primer
(F):5'- AGTAGAGCCTACTTGCTGCTCAATAC -3'
(R):5'- TTCATTTCACCACCGTGCAGATAAAG -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation