Mutagenetix > Incidental Mutation

Incidental Mutation 'R9169:Dchs1'

696264

Institutional Source

Beutler Lab

Gene Symbol

Dchs1

Ensembl Gene

ENSMUSG00000036862

Gene Name

dachsous cadherin related 1

Synonyms

C130033F22Rik, 3110041P15Rik

MMRRC Submission

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R9169 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

105402197-105436861 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 105422114 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 102 (D102G)

Ref Sequence

ENSEMBL: ENSMUSP00000077574 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078482]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000078482
AA Change: D102G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000077574
Gene: ENSMUSG00000036862
AA Change: D102G

Domain	Start	End	E-Value	Type
signal peptide	1	36	N/A	INTRINSIC
CA	58	135	5.2e-11	SMART
CA	159	247	6.1e-17	SMART
CA	271	354	2.6e-30	SMART
CA	382	464	7.8e-26	SMART
CA	489	570	1.2e-34	SMART
CA	594	677	1.9e-27	SMART
CA	701	782	5.3e-11	SMART
CA	806	886	1e-12	SMART
CA	910	990	3.3e-14	SMART
CA	1016	1097	3.6e-18	SMART
CA	1121	1203	3.1e-34	SMART
CA	1233	1307	8.8e-16	SMART
low complexity region	1323	1335	N/A	INTRINSIC
CA	1344	1427	9.9e-9	SMART
CA	1451	1537	1.5e-23	SMART
CA	1560	1640	7.2e-32	SMART
CA	1664	1742	1.8e-31	SMART
CA	1765	1846	7.8e-30	SMART
CA	1870	1951	3.7e-26	SMART
low complexity region	1957	1965	N/A	INTRINSIC
CA	1979	2059	1.1e-6	SMART
CA	2083	2162	2.7e-18	SMART
CA	2186	2268	2.2e-26	SMART
CA	2291	2367	1e-18	SMART
CA	2391	2473	1.8e-23	SMART
CA	2497	2593	3.5e-21	SMART
CA	2617	2697	1.2e-25	SMART
CA	2721	2804	1.9e-18	SMART
CA	2828	2919	3e-3	SMART
transmembrane domain	2932	2954	N/A	INTRINSIC
low complexity region	3001	3017	N/A	INTRINSIC
low complexity region	3046	3055	N/A	INTRINSIC
low complexity region	3088	3097	N/A	INTRINSIC
low complexity region	3185	3196	N/A	INTRINSIC
low complexity region	3237	3259	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (92/92)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality, growth retardation, small lungs, abnormal cochlea morphology, abnormal kidney morphology, cardiovascular abnormalities and skeletal abnormalities. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 91 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610021A01Rik	A	T	7: 41,261,109 (GRCm39)		probably benign	Het
9330182O14Rik	A	T	15: 40,005,632 (GRCm39)	K17*	probably null	Het
Adamtsl3	A	C	7: 82,223,188 (GRCm39)	I990L	probably damaging	Het
Add1	T	A	5: 34,788,122 (GRCm39)	S724T	possibly damaging	Het
Afdn	A	G	17: 14,072,627 (GRCm39)	N865S	probably benign	Het
Amot	A	T	X: 144,244,745 (GRCm39)	L435H		Het
Ap1m2	T	A	9: 21,223,523 (GRCm39)	I8F	probably benign	Het
Atp8a1	T	C	5: 67,824,944 (GRCm39)	T811A		Het
Axin2	A	G	11: 108,822,378 (GRCm39)	D310G	probably damaging	Het
Bin1	T	G	18: 32,562,251 (GRCm39)	F379L	possibly damaging	Het
Bin2	C	A	15: 100,554,631 (GRCm39)	S91I	possibly damaging	Het
Birc5	A	G	11: 117,743,599 (GRCm39)	N111S	probably benign	Het
Blk	T	A	14: 63,620,130 (GRCm39)	N137Y	probably damaging	Het
Cacna1d	G	A	14: 29,796,873 (GRCm39)	A1534V	probably damaging	Het
Cacna2d1	T	C	5: 16,451,757 (GRCm39)	V207A	probably damaging	Het
Ccr3	A	G	9: 123,828,949 (GRCm39)	I95V	probably benign	Het
Celsr2	T	C	3: 108,309,862 (GRCm39)	D1579G	probably benign	Het
Cfap36	C	A	11: 29,196,541 (GRCm39)	K19N	probably benign	Het
Cfap52	C	T	11: 67,844,860 (GRCm39)	V70M	possibly damaging	Het
Chid1	A	T	7: 141,093,722 (GRCm39)	I298N	probably damaging	Het
Clstn1	G	T	4: 149,731,322 (GRCm39)	R888L	possibly damaging	Het
Col6a5	T	A	9: 105,822,596 (GRCm39)	T254S	unknown	Het
Coro6	C	T	11: 77,359,329 (GRCm39)	P301S	probably damaging	Het
Cstdc2	A	G	2: 148,692,589 (GRCm39)		probably null	Het
Dnah14	T	C	1: 181,433,381 (GRCm39)	F353L	probably benign	Het
Dnajc10	A	T	2: 80,163,315 (GRCm39)	I344L	probably benign	Het
Dst	T	C	1: 34,303,652 (GRCm39)	V4026A	probably damaging	Het
Exo1	A	G	1: 175,715,203 (GRCm39)	E114G	possibly damaging	Het
Fabp7	A	G	10: 57,662,439 (GRCm39)	I109V	probably benign	Het
Fars2	T	C	13: 36,416,109 (GRCm39)	F206S	probably damaging	Het
Gbp8	C	T	5: 105,179,155 (GRCm39)	A115T	possibly damaging	Het
Gm17067	T	C	7: 42,357,627 (GRCm39)	T292A	probably benign	Het
Gp2	T	C	7: 119,041,929 (GRCm39)	D532G	probably benign	Het
Gtf2i	C	A	5: 134,271,534 (GRCm39)	A917S	probably damaging	Het
Guca1b	A	G	17: 47,702,827 (GRCm39)	E169G	possibly damaging	Het
Hdac1	A	T	4: 129,428,499 (GRCm39)	Y24N	probably damaging	Het
Hepacam	T	C	9: 37,293,693 (GRCm39)	F251L	probably damaging	Het
Hmcn1	G	T	1: 150,506,092 (GRCm39)	N3811K	probably damaging	Het
Htra4	A	T	8: 25,520,133 (GRCm39)	M391K	probably damaging	Het
Ino80d	T	C	1: 63,097,930 (GRCm39)	T760A	probably benign	Het
Ints1	T	G	5: 139,748,586 (GRCm39)	T1074P	probably benign	Het
Itga6	A	T	2: 71,647,015 (GRCm39)	Q75L	possibly damaging	Het
Mapk14	A	C	17: 28,960,814 (GRCm39)	N272T	probably benign	Het
Meikin	A	T	11: 54,285,517 (GRCm39)	T185S	possibly damaging	Het
Moxd2	C	T	6: 40,860,490 (GRCm39)	G318D	possibly damaging	Het
Mtmr3	G	A	11: 4,437,739 (GRCm39)	T905I	probably benign	Het
Muc16	A	G	9: 18,567,824 (GRCm39)	I1565T	unknown	Het
Myh14	A	G	7: 44,271,281 (GRCm39)	S1500P	possibly damaging	Het
Nfkb1	T	C	3: 135,310,874 (GRCm39)	E475G	probably benign	Het
Ngef	C	A	1: 87,473,581 (GRCm39)	R67L	probably benign	Het
Olr1	T	C	6: 129,470,528 (GRCm39)	E213G	probably damaging	Het
Or13c3	T	A	4: 52,856,052 (GRCm39)	I154F	probably damaging	Het
Or5b124	A	G	19: 13,610,903 (GRCm39)	I143V	probably benign	Het
Or8g21	A	G	9: 38,906,573 (GRCm39)	S53P	probably benign	Het
Or9r3	A	C	10: 129,947,723 (GRCm39)	I312R	probably benign	Het
Pcdhga3	C	T	18: 37,809,088 (GRCm39)	L514F	probably damaging	Het
Pcnt	A	G	10: 76,221,572 (GRCm39)	M2018T	possibly damaging	Het
Pde8a	C	T	7: 80,982,619 (GRCm39)	T746I	probably damaging	Het
Pik3ca	T	C	3: 32,503,755 (GRCm39)		probably null	Het
Psapl1	A	G	5: 36,362,880 (GRCm39)	S491G	possibly damaging	Het
Psmf1	A	T	2: 151,577,457 (GRCm39)	D73E	probably benign	Het
Ptprcap	A	G	19: 4,206,358 (GRCm39)	D147G	probably benign	Het
Ramacl	T	C	13: 67,056,063 (GRCm39)	F19L	probably damaging	Het
Rdh8	T	A	9: 20,736,935 (GRCm39)	V309E	possibly damaging	Het
Rhobtb3	T	A	13: 76,041,121 (GRCm39)	T396S	probably benign	Het
Rpa1	A	T	11: 75,200,999 (GRCm39)	L475*	probably null	Het
Rtkn	T	A	6: 83,129,190 (GRCm39)	S562T	probably damaging	Het
Saxo5	A	T	8: 3,525,967 (GRCm39)	Y40F	possibly damaging	Het
Scamp1	C	T	13: 94,389,533 (GRCm39)	D35N	probably benign	Het
Scarb1	C	T	5: 125,371,146 (GRCm39)	A309T	probably damaging	Het
Scube1	G	A	15: 83,543,298 (GRCm39)	T180M	possibly damaging	Het
Sez6	T	G	11: 77,868,473 (GRCm39)	F945V	probably damaging	Het
Sf3a1	C	T	11: 4,116,681 (GRCm39)	T124M	probably benign	Het
Smchd1	T	C	17: 71,722,659 (GRCm39)	K759E	probably damaging	Het
Sort1	C	A	3: 108,247,994 (GRCm39)	C446*	probably null	Het
Sun1	T	A	5: 139,219,273 (GRCm39)	S360T	probably benign	Het
Supv3l1	A	G	10: 62,268,238 (GRCm39)	F536L	probably damaging	Het
Taar6	A	C	10: 23,861,273 (GRCm39)	V91G	probably damaging	Het
Themis	C	A	10: 28,658,233 (GRCm39)	T420N	probably benign	Het
Thoc2l	T	A	5: 104,666,348 (GRCm39)	L290H	probably damaging	Het
Tmc2	T	A	2: 130,083,516 (GRCm39)	I491N	probably damaging	Het
Trmt112	T	C	19: 6,888,187 (GRCm39)	I113T	probably damaging	Het
Ttc14	C	T	3: 33,857,071 (GRCm39)	Q183*	probably null	Het
Txndc16	T	A	14: 45,373,385 (GRCm39)	D748V	probably damaging	Het
Xkr6	A	G	14: 63,844,067 (GRCm39)	D30G	possibly damaging	Het
Zc3h14	C	T	12: 98,745,505 (GRCm39)	S498L	probably damaging	Het
Zc3h7b	A	C	15: 81,661,184 (GRCm39)	D341A	probably benign	Het
Zfp108	T	A	7: 23,960,923 (GRCm39)	C505S	probably damaging	Het
Zfp354c	A	C	11: 50,706,088 (GRCm39)	L329R	probably damaging	Het
Zfyve16	T	A	13: 92,657,871 (GRCm39)	D680V	probably damaging	Het
Znfx1	A	G	2: 166,897,185 (GRCm39)	F580L	probably benign	Het

Other mutations in Dchs1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00235:Dchs1	APN	7	105,407,950 (GRCm39)	missense	probably damaging	1.00
IGL00422:Dchs1	APN	7	105,407,236 (GRCm39)	missense	possibly damaging	0.88
IGL00427:Dchs1	APN	7	105,407,631 (GRCm39)	missense	probably damaging	0.98
IGL00469:Dchs1	APN	7	105,404,468 (GRCm39)	missense	probably damaging	1.00
IGL00470:Dchs1	APN	7	105,407,414 (GRCm39)	missense	probably damaging	1.00
IGL00534:Dchs1	APN	7	105,407,150 (GRCm39)	missense	probably benign
IGL01292:Dchs1	APN	7	105,410,098 (GRCm39)	missense	probably damaging	0.98
IGL01380:Dchs1	APN	7	105,411,418 (GRCm39)	missense	probably damaging	1.00
IGL01396:Dchs1	APN	7	105,421,490 (GRCm39)	missense	probably damaging	1.00
IGL01448:Dchs1	APN	7	105,421,134 (GRCm39)	missense	probably damaging	0.98
IGL01759:Dchs1	APN	7	105,404,509 (GRCm39)	missense	probably benign	0.00
IGL01829:Dchs1	APN	7	105,404,604 (GRCm39)	missense	probably damaging	0.99
IGL01946:Dchs1	APN	7	105,408,312 (GRCm39)	missense	probably damaging	1.00
IGL01955:Dchs1	APN	7	105,406,798 (GRCm39)	missense	probably benign	0.00
IGL02012:Dchs1	APN	7	105,413,504 (GRCm39)	missense	probably damaging	0.98
IGL02222:Dchs1	APN	7	105,414,094 (GRCm39)	missense	probably damaging	1.00
IGL02261:Dchs1	APN	7	105,421,776 (GRCm39)	missense	probably damaging	1.00
IGL02365:Dchs1	APN	7	105,404,395 (GRCm39)	missense	probably benign	0.22
IGL02430:Dchs1	APN	7	105,421,178 (GRCm39)	missense	probably benign	0.34
IGL02500:Dchs1	APN	7	105,405,013 (GRCm39)	missense	probably benign
IGL02741:Dchs1	APN	7	105,406,530 (GRCm39)	missense	probably damaging	1.00
IGL02890:Dchs1	APN	7	105,405,698 (GRCm39)	missense	probably damaging	1.00
IGL03213:Dchs1	APN	7	105,404,279 (GRCm39)	missense	probably damaging	1.00
G1patch:Dchs1	UTSW	7	105,408,000 (GRCm39)	missense	probably damaging	0.99
P0026:Dchs1	UTSW	7	105,407,612 (GRCm39)	missense	probably damaging	0.99
PIT4377001:Dchs1	UTSW	7	105,406,795 (GRCm39)	missense	probably damaging	1.00
PIT4791001:Dchs1	UTSW	7	105,408,178 (GRCm39)	missense	probably damaging	1.00
R0013:Dchs1	UTSW	7	105,405,043 (GRCm39)	missense	possibly damaging	0.90
R0090:Dchs1	UTSW	7	105,405,139 (GRCm39)	missense	probably benign	0.18
R0091:Dchs1	UTSW	7	105,415,301 (GRCm39)	splice site	probably benign
R0193:Dchs1	UTSW	7	105,414,190 (GRCm39)	missense	probably benign	0.40
R0395:Dchs1	UTSW	7	105,407,745 (GRCm39)	missense	probably damaging	1.00
R0448:Dchs1	UTSW	7	105,415,134 (GRCm39)	missense	probably benign	0.00
R0480:Dchs1	UTSW	7	105,420,696 (GRCm39)	missense	probably benign	0.14
R0485:Dchs1	UTSW	7	105,421,934 (GRCm39)	missense	probably benign	0.00
R0566:Dchs1	UTSW	7	105,408,402 (GRCm39)	missense	probably benign	0.00
R0571:Dchs1	UTSW	7	105,421,203 (GRCm39)	missense	probably damaging	1.00
R0573:Dchs1	UTSW	7	105,407,985 (GRCm39)	missense	probably damaging	0.98
R0577:Dchs1	UTSW	7	105,413,462 (GRCm39)	missense	possibly damaging	0.78
R0622:Dchs1	UTSW	7	105,412,656 (GRCm39)	missense	probably damaging	1.00
R0654:Dchs1	UTSW	7	105,421,556 (GRCm39)	missense	probably damaging	1.00
R0677:Dchs1	UTSW	7	105,414,191 (GRCm39)	missense	probably damaging	1.00
R1171:Dchs1	UTSW	7	105,406,921 (GRCm39)	missense	probably benign
R1241:Dchs1	UTSW	7	105,407,385 (GRCm39)	missense	probably damaging	1.00
R1389:Dchs1	UTSW	7	105,404,778 (GRCm39)	missense	probably benign	0.40
R1427:Dchs1	UTSW	7	105,415,398 (GRCm39)	missense	probably benign	0.06
R1458:Dchs1	UTSW	7	105,404,451 (GRCm39)	missense	probably damaging	1.00
R1513:Dchs1	UTSW	7	105,421,278 (GRCm39)	nonsense	probably null
R1524:Dchs1	UTSW	7	105,413,732 (GRCm39)	missense	probably damaging	1.00
R1525:Dchs1	UTSW	7	105,408,138 (GRCm39)	missense	probably damaging	1.00
R1534:Dchs1	UTSW	7	105,421,247 (GRCm39)	missense	probably damaging	0.98
R1567:Dchs1	UTSW	7	105,421,068 (GRCm39)	missense	probably benign	0.01
R1577:Dchs1	UTSW	7	105,415,162 (GRCm39)	missense	probably damaging	1.00
R1603:Dchs1	UTSW	7	105,411,977 (GRCm39)	missense	probably benign	0.24
R1676:Dchs1	UTSW	7	105,404,128 (GRCm39)	missense	probably benign	0.40
R1794:Dchs1	UTSW	7	105,420,927 (GRCm39)	missense	probably benign	0.02
R1826:Dchs1	UTSW	7	105,406,834 (GRCm39)	missense	probably damaging	1.00
R1892:Dchs1	UTSW	7	105,413,363 (GRCm39)	missense	probably benign	0.00
R1924:Dchs1	UTSW	7	105,421,487 (GRCm39)	missense	possibly damaging	0.81
R1932:Dchs1	UTSW	7	105,415,109 (GRCm39)	missense	probably damaging	1.00
R1962:Dchs1	UTSW	7	105,413,408 (GRCm39)	missense	probably damaging	1.00
R1985:Dchs1	UTSW	7	105,421,605 (GRCm39)	missense	possibly damaging	0.72
R1993:Dchs1	UTSW	7	105,411,755 (GRCm39)	missense	probably benign	0.00
R2007:Dchs1	UTSW	7	105,404,532 (GRCm39)	missense	probably damaging	1.00
R2316:Dchs1	UTSW	7	105,413,411 (GRCm39)	missense	possibly damaging	0.71
R2351:Dchs1	UTSW	7	105,403,301 (GRCm39)	missense	probably benign
R2474:Dchs1	UTSW	7	105,404,281 (GRCm39)	missense	probably benign	0.37
R2474:Dchs1	UTSW	7	105,422,045 (GRCm39)	missense	probably damaging	1.00
R3429:Dchs1	UTSW	7	105,405,711 (GRCm39)	missense	possibly damaging	0.85
R3430:Dchs1	UTSW	7	105,405,711 (GRCm39)	missense	possibly damaging	0.85
R3737:Dchs1	UTSW	7	105,411,523 (GRCm39)	missense	possibly damaging	0.88
R3767:Dchs1	UTSW	7	105,406,292 (GRCm39)	missense	possibly damaging	0.67
R3874:Dchs1	UTSW	7	105,410,842 (GRCm39)	missense	probably damaging	1.00
R3883:Dchs1	UTSW	7	105,411,770 (GRCm39)	missense	probably damaging	1.00
R4105:Dchs1	UTSW	7	105,414,347 (GRCm39)	missense	probably damaging	1.00
R4209:Dchs1	UTSW	7	105,415,397 (GRCm39)	missense	probably damaging	0.99
R4329:Dchs1	UTSW	7	105,402,966 (GRCm39)	missense	probably damaging	1.00
R4516:Dchs1	UTSW	7	105,404,059 (GRCm39)	missense	probably damaging	1.00
R4579:Dchs1	UTSW	7	105,408,180 (GRCm39)	missense	probably benign
R4579:Dchs1	UTSW	7	105,403,972 (GRCm39)	missense	probably damaging	1.00
R4588:Dchs1	UTSW	7	105,405,248 (GRCm39)	missense	probably benign
R4613:Dchs1	UTSW	7	105,421,931 (GRCm39)	missense	probably damaging	1.00
R4632:Dchs1	UTSW	7	105,403,562 (GRCm39)	missense	probably benign	0.02
R4696:Dchs1	UTSW	7	105,413,834 (GRCm39)	missense	probably damaging	1.00
R4725:Dchs1	UTSW	7	105,414,759 (GRCm39)	missense	probably damaging	1.00
R4725:Dchs1	UTSW	7	105,404,460 (GRCm39)	missense	probably damaging	0.98
R4738:Dchs1	UTSW	7	105,407,880 (GRCm39)	missense	probably damaging	0.96
R4768:Dchs1	UTSW	7	105,420,827 (GRCm39)	missense	possibly damaging	0.96
R4784:Dchs1	UTSW	7	105,415,133 (GRCm39)	missense	probably damaging	1.00
R4864:Dchs1	UTSW	7	105,404,460 (GRCm39)	missense	probably damaging	0.98
R4880:Dchs1	UTSW	7	105,404,937 (GRCm39)	missense	probably benign	0.00
R4909:Dchs1	UTSW	7	105,415,462 (GRCm39)	missense	probably damaging	1.00
R5102:Dchs1	UTSW	7	105,421,384 (GRCm39)	missense	probably benign	0.09
R5109:Dchs1	UTSW	7	105,414,221 (GRCm39)	missense	probably benign
R5126:Dchs1	UTSW	7	105,402,724 (GRCm39)	missense	probably damaging	1.00
R5149:Dchs1	UTSW	7	105,404,865 (GRCm39)	missense	probably damaging	0.98
R5330:Dchs1	UTSW	7	105,403,809 (GRCm39)	missense	probably damaging	1.00
R5384:Dchs1	UTSW	7	105,421,262 (GRCm39)	missense	probably damaging	1.00
R5384:Dchs1	UTSW	7	105,407,236 (GRCm39)	missense	probably damaging	1.00
R5386:Dchs1	UTSW	7	105,407,236 (GRCm39)	missense	probably damaging	1.00
R5622:Dchs1	UTSW	7	105,404,500 (GRCm39)	missense	probably benign	0.11
R5623:Dchs1	UTSW	7	105,421,976 (GRCm39)	missense	probably damaging	1.00
R5708:Dchs1	UTSW	7	105,422,016 (GRCm39)	missense	probably damaging	1.00
R5718:Dchs1	UTSW	7	105,404,955 (GRCm39)	missense	probably benign	0.01
R5743:Dchs1	UTSW	7	105,420,803 (GRCm39)	missense	probably benign
R5759:Dchs1	UTSW	7	105,413,383 (GRCm39)	missense	probably damaging	0.99
R5772:Dchs1	UTSW	7	105,422,247 (GRCm39)	missense	probably damaging	1.00
R5860:Dchs1	UTSW	7	105,421,242 (GRCm39)	missense	probably damaging	1.00
R5916:Dchs1	UTSW	7	105,408,373 (GRCm39)	missense	probably damaging	1.00
R5965:Dchs1	UTSW	7	105,405,132 (GRCm39)	missense	probably damaging	1.00
R5997:Dchs1	UTSW	7	105,403,302 (GRCm39)	missense	probably benign	0.08
R6065:Dchs1	UTSW	7	105,404,628 (GRCm39)	missense	probably damaging	1.00
R6136:Dchs1	UTSW	7	105,410,132 (GRCm39)	missense	probably benign
R6137:Dchs1	UTSW	7	105,414,313 (GRCm39)	missense	probably damaging	0.99
R6324:Dchs1	UTSW	7	105,414,145 (GRCm39)	missense	probably benign	0.05
R6363:Dchs1	UTSW	7	105,407,679 (GRCm39)	missense	probably benign	0.12
R6466:Dchs1	UTSW	7	105,413,748 (GRCm39)	missense	probably benign	0.09
R6544:Dchs1	UTSW	7	105,407,385 (GRCm39)	missense	probably damaging	1.00
R6572:Dchs1	UTSW	7	105,408,013 (GRCm39)	missense	possibly damaging	0.94
R6579:Dchs1	UTSW	7	105,412,120 (GRCm39)	missense	probably benign	0.17
R6632:Dchs1	UTSW	7	105,411,085 (GRCm39)	missense	probably damaging	1.00
R6725:Dchs1	UTSW	7	105,408,000 (GRCm39)	missense	probably damaging	0.99
R6789:Dchs1	UTSW	7	105,406,210 (GRCm39)	missense	possibly damaging	0.61
R6868:Dchs1	UTSW	7	105,412,710 (GRCm39)	missense	possibly damaging	0.91
R7058:Dchs1	UTSW	7	105,406,228 (GRCm39)	missense	probably benign
R7064:Dchs1	UTSW	7	105,412,392 (GRCm39)	missense	probably damaging	0.99
R7076:Dchs1	UTSW	7	105,411,078 (GRCm39)	missense	probably benign	0.04
R7191:Dchs1	UTSW	7	105,414,646 (GRCm39)	missense	possibly damaging	0.89
R7298:Dchs1	UTSW	7	105,404,338 (GRCm39)	nonsense	probably null
R7380:Dchs1	UTSW	7	105,407,835 (GRCm39)	missense	probably benign	0.35
R7438:Dchs1	UTSW	7	105,404,155 (GRCm39)	missense	probably benign	0.30
R7496:Dchs1	UTSW	7	105,411,066 (GRCm39)	missense	probably damaging	1.00
R7534:Dchs1	UTSW	7	105,421,580 (GRCm39)	missense	probably benign	0.00
R7604:Dchs1	UTSW	7	105,415,189 (GRCm39)	missense	probably damaging	1.00
R7631:Dchs1	UTSW	7	105,408,445 (GRCm39)	missense	probably benign
R7821:Dchs1	UTSW	7	105,414,352 (GRCm39)	missense	probably benign	0.00
R7834:Dchs1	UTSW	7	105,414,774 (GRCm39)	missense	probably benign	0.39
R7841:Dchs1	UTSW	7	105,412,180 (GRCm39)	missense	probably benign
R7913:Dchs1	UTSW	7	105,408,435 (GRCm39)	missense	possibly damaging	0.61
R8041:Dchs1	UTSW	7	105,404,395 (GRCm39)	missense	probably benign	0.45
R8076:Dchs1	UTSW	7	105,411,189 (GRCm39)	missense	probably damaging	1.00
R8076:Dchs1	UTSW	7	105,405,128 (GRCm39)	missense	possibly damaging	0.52
R8087:Dchs1	UTSW	7	105,402,706 (GRCm39)	missense	probably benign	0.41
R8125:Dchs1	UTSW	7	105,414,089 (GRCm39)	missense	possibly damaging	0.91
R8223:Dchs1	UTSW	7	105,411,824 (GRCm39)	missense	possibly damaging	0.81
R8239:Dchs1	UTSW	7	105,414,718 (GRCm39)	missense	probably benign	0.22
R8476:Dchs1	UTSW	7	105,408,015 (GRCm39)	missense	probably benign	0.05
R8497:Dchs1	UTSW	7	105,408,168 (GRCm39)	missense	probably damaging	1.00
R8770:Dchs1	UTSW	7	105,420,945 (GRCm39)	missense	probably damaging	1.00
R8856:Dchs1	UTSW	7	105,410,064 (GRCm39)	missense	probably damaging	1.00
R8866:Dchs1	UTSW	7	105,404,597 (GRCm39)	missense	probably benign	0.00
R8948:Dchs1	UTSW	7	105,408,212 (GRCm39)	missense	probably benign	0.30
R8950:Dchs1	UTSW	7	105,408,212 (GRCm39)	missense	probably benign	0.30
R9029:Dchs1	UTSW	7	105,402,919 (GRCm39)	missense	probably benign	0.13
R9039:Dchs1	UTSW	7	105,405,215 (GRCm39)	missense	probably benign	0.11
R9081:Dchs1	UTSW	7	105,403,636 (GRCm39)	missense	probably benign	0.00
R9134:Dchs1	UTSW	7	105,404,910 (GRCm39)	missense	probably damaging	0.96
R9159:Dchs1	UTSW	7	105,415,126 (GRCm39)	missense	probably benign
R9162:Dchs1	UTSW	7	105,414,732 (GRCm39)	missense	probably damaging	1.00
R9262:Dchs1	UTSW	7	105,404,833 (GRCm39)	missense	probably damaging	1.00
R9292:Dchs1	UTSW	7	105,403,120 (GRCm39)	missense	probably damaging	1.00
R9325:Dchs1	UTSW	7	105,415,402 (GRCm39)	missense	possibly damaging	0.51
R9376:Dchs1	UTSW	7	105,414,981 (GRCm39)	critical splice donor site	probably null
R9392:Dchs1	UTSW	7	105,421,869 (GRCm39)	missense	probably benign	0.09
R9619:Dchs1	UTSW	7	105,413,662 (GRCm39)	missense	probably benign	0.07
R9680:Dchs1	UTSW	7	105,411,625 (GRCm39)	missense	probably damaging	1.00
R9687:Dchs1	UTSW	7	105,407,191 (GRCm39)	missense	probably damaging	0.99
R9747:Dchs1	UTSW	7	105,412,682 (GRCm39)	missense	probably damaging	1.00
Z1177:Dchs1	UTSW	7	105,406,900 (GRCm39)	missense	probably damaging	1.00
Z1177:Dchs1	UTSW	7	105,407,758 (GRCm39)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- TAGCGCATACCCTTGGGTTC -3'
(R):5'- CCTACAGATCGACGAGGAAC -3'

Sequencing Primer
(F):5'- ATCTGCATCACGAGCAGG -3'
(R):5'- GATCGACGAGGAACAACCAGC -3'

Posted On

2022-02-07