Incidental Mutation 'R9169:Sez6'
| ID |
696290 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sez6
|
| Ensembl Gene |
ENSMUSG00000000632 |
| Gene Name |
seizure related gene 6 |
| Synonyms |
sez-6, D11Bhm177e |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9169 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
77821626-77869874 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 77868473 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Valine
at position 945
(F945V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091532
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000000646]
[ENSMUST00000093995]
|
| AlphaFold |
Q7TSK2 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000000646
AA Change: F932V
PolyPhen 2
Score 0.925 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000000646
Gene: ENSMUSG00000000632
AA Change: F932V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
910 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000093995
AA Change: F945V
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000091532
Gene: ENSMUSG00000000632
AA Change: F945V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
923 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140630
|
| SMART Domains |
Protein: ENSMUSP00000115660
Gene: ENSMUSG00000000632
| Domain | Start | End | E-Value | Type |
|---|
|
CUB
|
29 |
140 |
9.8e-28 |
SMART |
|
CCP
|
157 |
214 |
5.43e-12 |
SMART |
|
Pfam:CUB
|
218 |
278 |
1.6e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151982
|
| SMART Domains |
Protein: ENSMUSP00000132041
Gene: ENSMUSG00000000632
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
57 |
69 |
N/A |
INTRINSIC |
|
CUB
|
75 |
184 |
9.36e-2 |
SMART |
|
CCP
|
188 |
243 |
1.23e-10 |
SMART |
|
CUB
|
247 |
358 |
8.08e-29 |
SMART |
|
low complexity region
|
379 |
394 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (92/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit increased short dendrites, decreased excitatory synaptic signaling, resistance to pharmacologically induces seizures, decreased activity and impaired learning and coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
A |
T |
7: 41,261,109 (GRCm39) |
|
probably benign |
Het |
| 9330182O14Rik |
A |
T |
15: 40,005,632 (GRCm39) |
K17* |
probably null |
Het |
| Adamtsl3 |
A |
C |
7: 82,223,188 (GRCm39) |
I990L |
probably damaging |
Het |
| Add1 |
T |
A |
5: 34,788,122 (GRCm39) |
S724T |
possibly damaging |
Het |
| Afdn |
A |
G |
17: 14,072,627 (GRCm39) |
N865S |
probably benign |
Het |
| Amot |
A |
T |
X: 144,244,745 (GRCm39) |
L435H |
|
Het |
| Ap1m2 |
T |
A |
9: 21,223,523 (GRCm39) |
I8F |
probably benign |
Het |
| Atp8a1 |
T |
C |
5: 67,824,944 (GRCm39) |
T811A |
|
Het |
| Axin2 |
A |
G |
11: 108,822,378 (GRCm39) |
D310G |
probably damaging |
Het |
| Bin1 |
T |
G |
18: 32,562,251 (GRCm39) |
F379L |
possibly damaging |
Het |
| Bin2 |
C |
A |
15: 100,554,631 (GRCm39) |
S91I |
possibly damaging |
Het |
| Birc5 |
A |
G |
11: 117,743,599 (GRCm39) |
N111S |
probably benign |
Het |
| Blk |
T |
A |
14: 63,620,130 (GRCm39) |
N137Y |
probably damaging |
Het |
| Cacna1d |
G |
A |
14: 29,796,873 (GRCm39) |
A1534V |
probably damaging |
Het |
| Cacna2d1 |
T |
C |
5: 16,451,757 (GRCm39) |
V207A |
probably damaging |
Het |
| Ccr3 |
A |
G |
9: 123,828,949 (GRCm39) |
I95V |
probably benign |
Het |
| Celsr2 |
T |
C |
3: 108,309,862 (GRCm39) |
D1579G |
probably benign |
Het |
| Cfap36 |
C |
A |
11: 29,196,541 (GRCm39) |
K19N |
probably benign |
Het |
| Cfap52 |
C |
T |
11: 67,844,860 (GRCm39) |
V70M |
possibly damaging |
Het |
| Chid1 |
A |
T |
7: 141,093,722 (GRCm39) |
I298N |
probably damaging |
Het |
| Clstn1 |
G |
T |
4: 149,731,322 (GRCm39) |
R888L |
possibly damaging |
Het |
| Col6a5 |
T |
A |
9: 105,822,596 (GRCm39) |
T254S |
unknown |
Het |
| Coro6 |
C |
T |
11: 77,359,329 (GRCm39) |
P301S |
probably damaging |
Het |
| Cstdc2 |
A |
G |
2: 148,692,589 (GRCm39) |
|
probably null |
Het |
| Dchs1 |
T |
C |
7: 105,422,114 (GRCm39) |
D102G |
probably damaging |
Het |
| Dnah14 |
T |
C |
1: 181,433,381 (GRCm39) |
F353L |
probably benign |
Het |
| Dnajc10 |
A |
T |
2: 80,163,315 (GRCm39) |
I344L |
probably benign |
Het |
| Dst |
T |
C |
1: 34,303,652 (GRCm39) |
V4026A |
probably damaging |
Het |
| Exo1 |
A |
G |
1: 175,715,203 (GRCm39) |
E114G |
possibly damaging |
Het |
| Fabp7 |
A |
G |
10: 57,662,439 (GRCm39) |
I109V |
probably benign |
Het |
| Fars2 |
T |
C |
13: 36,416,109 (GRCm39) |
F206S |
probably damaging |
Het |
| Gbp8 |
C |
T |
5: 105,179,155 (GRCm39) |
A115T |
possibly damaging |
Het |
| Gm17067 |
T |
C |
7: 42,357,627 (GRCm39) |
T292A |
probably benign |
Het |
| Gp2 |
T |
C |
7: 119,041,929 (GRCm39) |
D532G |
probably benign |
Het |
| Gtf2i |
C |
A |
5: 134,271,534 (GRCm39) |
A917S |
probably damaging |
Het |
| Guca1b |
A |
G |
17: 47,702,827 (GRCm39) |
E169G |
possibly damaging |
Het |
| Hdac1 |
A |
T |
4: 129,428,499 (GRCm39) |
Y24N |
probably damaging |
Het |
| Hepacam |
T |
C |
9: 37,293,693 (GRCm39) |
F251L |
probably damaging |
Het |
| Hmcn1 |
G |
T |
1: 150,506,092 (GRCm39) |
N3811K |
probably damaging |
Het |
| Htra4 |
A |
T |
8: 25,520,133 (GRCm39) |
M391K |
probably damaging |
Het |
| Ino80d |
T |
C |
1: 63,097,930 (GRCm39) |
T760A |
probably benign |
Het |
| Ints1 |
T |
G |
5: 139,748,586 (GRCm39) |
T1074P |
probably benign |
Het |
| Itga6 |
A |
T |
2: 71,647,015 (GRCm39) |
Q75L |
possibly damaging |
Het |
| Mapk14 |
A |
C |
17: 28,960,814 (GRCm39) |
N272T |
probably benign |
Het |
| Meikin |
A |
T |
11: 54,285,517 (GRCm39) |
T185S |
possibly damaging |
Het |
| Moxd2 |
C |
T |
6: 40,860,490 (GRCm39) |
G318D |
possibly damaging |
Het |
| Mtmr3 |
G |
A |
11: 4,437,739 (GRCm39) |
T905I |
probably benign |
Het |
| Muc16 |
A |
G |
9: 18,567,824 (GRCm39) |
I1565T |
unknown |
Het |
| Myh14 |
A |
G |
7: 44,271,281 (GRCm39) |
S1500P |
possibly damaging |
Het |
| Nfkb1 |
T |
C |
3: 135,310,874 (GRCm39) |
E475G |
probably benign |
Het |
| Ngef |
C |
A |
1: 87,473,581 (GRCm39) |
R67L |
probably benign |
Het |
| Olr1 |
T |
C |
6: 129,470,528 (GRCm39) |
E213G |
probably damaging |
Het |
| Or13c3 |
T |
A |
4: 52,856,052 (GRCm39) |
I154F |
probably damaging |
Het |
| Or5b124 |
A |
G |
19: 13,610,903 (GRCm39) |
I143V |
probably benign |
Het |
| Or8g21 |
A |
G |
9: 38,906,573 (GRCm39) |
S53P |
probably benign |
Het |
| Or9r3 |
A |
C |
10: 129,947,723 (GRCm39) |
I312R |
probably benign |
Het |
| Pcdhga3 |
C |
T |
18: 37,809,088 (GRCm39) |
L514F |
probably damaging |
Het |
| Pcnt |
A |
G |
10: 76,221,572 (GRCm39) |
M2018T |
possibly damaging |
Het |
| Pde8a |
C |
T |
7: 80,982,619 (GRCm39) |
T746I |
probably damaging |
Het |
| Pik3ca |
T |
C |
3: 32,503,755 (GRCm39) |
|
probably null |
Het |
| Psapl1 |
A |
G |
5: 36,362,880 (GRCm39) |
S491G |
possibly damaging |
Het |
| Psmf1 |
A |
T |
2: 151,577,457 (GRCm39) |
D73E |
probably benign |
Het |
| Ptprcap |
A |
G |
19: 4,206,358 (GRCm39) |
D147G |
probably benign |
Het |
| Ramacl |
T |
C |
13: 67,056,063 (GRCm39) |
F19L |
probably damaging |
Het |
| Rdh8 |
T |
A |
9: 20,736,935 (GRCm39) |
V309E |
possibly damaging |
Het |
| Rhobtb3 |
T |
A |
13: 76,041,121 (GRCm39) |
T396S |
probably benign |
Het |
| Rpa1 |
A |
T |
11: 75,200,999 (GRCm39) |
L475* |
probably null |
Het |
| Rtkn |
T |
A |
6: 83,129,190 (GRCm39) |
S562T |
probably damaging |
Het |
| Saxo5 |
A |
T |
8: 3,525,967 (GRCm39) |
Y40F |
possibly damaging |
Het |
| Scamp1 |
C |
T |
13: 94,389,533 (GRCm39) |
D35N |
probably benign |
Het |
| Scarb1 |
C |
T |
5: 125,371,146 (GRCm39) |
A309T |
probably damaging |
Het |
| Scube1 |
G |
A |
15: 83,543,298 (GRCm39) |
T180M |
possibly damaging |
Het |
| Sf3a1 |
C |
T |
11: 4,116,681 (GRCm39) |
T124M |
probably benign |
Het |
| Smchd1 |
T |
C |
17: 71,722,659 (GRCm39) |
K759E |
probably damaging |
Het |
| Sort1 |
C |
A |
3: 108,247,994 (GRCm39) |
C446* |
probably null |
Het |
| Sun1 |
T |
A |
5: 139,219,273 (GRCm39) |
S360T |
probably benign |
Het |
| Supv3l1 |
A |
G |
10: 62,268,238 (GRCm39) |
F536L |
probably damaging |
Het |
| Taar6 |
A |
C |
10: 23,861,273 (GRCm39) |
V91G |
probably damaging |
Het |
| Themis |
C |
A |
10: 28,658,233 (GRCm39) |
T420N |
probably benign |
Het |
| Thoc2l |
T |
A |
5: 104,666,348 (GRCm39) |
L290H |
probably damaging |
Het |
| Tmc2 |
T |
A |
2: 130,083,516 (GRCm39) |
I491N |
probably damaging |
Het |
| Trmt112 |
T |
C |
19: 6,888,187 (GRCm39) |
I113T |
probably damaging |
Het |
| Ttc14 |
C |
T |
3: 33,857,071 (GRCm39) |
Q183* |
probably null |
Het |
| Txndc16 |
T |
A |
14: 45,373,385 (GRCm39) |
D748V |
probably damaging |
Het |
| Xkr6 |
A |
G |
14: 63,844,067 (GRCm39) |
D30G |
possibly damaging |
Het |
| Zc3h14 |
C |
T |
12: 98,745,505 (GRCm39) |
S498L |
probably damaging |
Het |
| Zc3h7b |
A |
C |
15: 81,661,184 (GRCm39) |
D341A |
probably benign |
Het |
| Zfp108 |
T |
A |
7: 23,960,923 (GRCm39) |
C505S |
probably damaging |
Het |
| Zfp354c |
A |
C |
11: 50,706,088 (GRCm39) |
L329R |
probably damaging |
Het |
| Zfyve16 |
T |
A |
13: 92,657,871 (GRCm39) |
D680V |
probably damaging |
Het |
| Znfx1 |
A |
G |
2: 166,897,185 (GRCm39) |
F580L |
probably benign |
Het |
|
| Other mutations in Sez6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01125:Sez6
|
APN |
11 |
77,868,115 (GRCm39) |
splice site |
probably benign |
|
|
IGL01142:Sez6
|
APN |
11 |
77,864,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02252:Sez6
|
APN |
11 |
77,865,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02332:Sez6
|
APN |
11 |
77,845,568 (GRCm39) |
splice site |
probably benign |
|
|
IGL02366:Sez6
|
APN |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02479:Sez6
|
APN |
11 |
77,868,852 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02963:Sez6
|
APN |
11 |
77,853,775 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
velum
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0089:Sez6
|
UTSW |
11 |
77,865,170 (GRCm39) |
splice site |
probably benign |
|
|
R0485:Sez6
|
UTSW |
11 |
77,844,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0598:Sez6
|
UTSW |
11 |
77,868,647 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0729:Sez6
|
UTSW |
11 |
77,867,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1117:Sez6
|
UTSW |
11 |
77,865,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1199:Sez6
|
UTSW |
11 |
77,844,711 (GRCm39) |
missense |
probably benign |
|
|
R1534:Sez6
|
UTSW |
11 |
77,853,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Sez6
|
UTSW |
11 |
77,844,329 (GRCm39) |
missense |
probably benign |
|
|
R1840:Sez6
|
UTSW |
11 |
77,844,543 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1929:Sez6
|
UTSW |
11 |
77,863,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Sez6
|
UTSW |
11 |
77,844,894 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3156:Sez6
|
UTSW |
11 |
77,844,605 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R3930:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3931:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4894:Sez6
|
UTSW |
11 |
77,866,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4904:Sez6
|
UTSW |
11 |
77,866,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5026:Sez6
|
UTSW |
11 |
77,859,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5040:Sez6
|
UTSW |
11 |
77,859,915 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5057:Sez6
|
UTSW |
11 |
77,863,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5093:Sez6
|
UTSW |
11 |
77,867,388 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5640:Sez6
|
UTSW |
11 |
77,864,585 (GRCm39) |
intron |
probably benign |
|
|
R6013:Sez6
|
UTSW |
11 |
77,864,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6126:Sez6
|
UTSW |
11 |
77,864,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6153:Sez6
|
UTSW |
11 |
77,868,648 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6279:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6300:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6475:Sez6
|
UTSW |
11 |
77,864,670 (GRCm39) |
|
|
|
|
R6722:Sez6
|
UTSW |
11 |
77,844,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6897:Sez6
|
UTSW |
11 |
77,844,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Sez6
|
UTSW |
11 |
77,844,695 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7012:Sez6
|
UTSW |
11 |
77,868,621 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7233:Sez6
|
UTSW |
11 |
77,863,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7265:Sez6
|
UTSW |
11 |
77,853,691 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7289:Sez6
|
UTSW |
11 |
77,865,149 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7405:Sez6
|
UTSW |
11 |
77,853,717 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7408:Sez6
|
UTSW |
11 |
77,844,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7485:Sez6
|
UTSW |
11 |
77,864,711 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7592:Sez6
|
UTSW |
11 |
77,868,876 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7778:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7793:Sez6
|
UTSW |
11 |
77,868,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Sez6
|
UTSW |
11 |
77,867,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7980:Sez6
|
UTSW |
11 |
77,844,668 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8008:Sez6
|
UTSW |
11 |
77,864,082 (GRCm39) |
nonsense |
probably null |
|
|
R8840:Sez6
|
UTSW |
11 |
77,867,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8947:Sez6
|
UTSW |
11 |
77,844,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Sez6
|
UTSW |
11 |
77,865,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9040:Sez6
|
UTSW |
11 |
77,864,762 (GRCm39) |
missense |
probably benign |
|
|
R9081:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9082:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9092:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9094:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9095:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9097:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9513:Sez6
|
UTSW |
11 |
77,865,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9632:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9646:Sez6
|
UTSW |
11 |
77,867,632 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9709:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
X0013:Sez6
|
UTSW |
11 |
77,845,606 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0067:Sez6
|
UTSW |
11 |
77,865,264 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1088:Sez6
|
UTSW |
11 |
77,864,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTACCATAGGCAGCTAATGG -3'
(R):5'- TCAAATGCTGACTCTACCGTG -3'
Sequencing Primer
(F):5'- GAGCTGGTCTCCAAATGTCTTTAAG -3'
(R):5'- ATGCTGACTCTACCGTGATGCG -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation