Incidental Mutation 'R9178:Apc2'
| ID |
696835 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Apc2
|
| Ensembl Gene |
ENSMUSG00000020135 |
| Gene Name |
APC regulator of WNT signaling pathway 2 |
| Synonyms |
APCL |
| MMRRC Submission |
068978-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.172)
|
| Stock # |
R9178 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
80131811-80154097 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 80150235 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Glutamic Acid
at position 1763
(G1763E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000100996
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020341]
[ENSMUST00000020349]
[ENSMUST00000105359]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000020341
|
| SMART Domains |
Protein: ENSMUSP00000020341
Gene: ENSMUSG00000020133
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UPF0449
|
6 |
103 |
7.5e-40 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000020349
AA Change: G1734E
PolyPhen 2
Score 0.033 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000020349
Gene: ENSMUSG00000020135
AA Change: G1734E
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1DEB|B
|
4 |
57 |
9e-17 |
PDB |
|
Pfam:Suppressor_APC
|
123 |
205 |
1.3e-28 |
PFAM |
|
coiled coil region
|
214 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
242 |
261 |
N/A |
INTRINSIC |
|
ARM
|
300 |
355 |
2.95e0 |
SMART |
|
ARM
|
417 |
468 |
2.22e-2 |
SMART |
|
ARM
|
470 |
511 |
3.22e0 |
SMART |
|
ARM
|
513 |
555 |
3.56e-1 |
SMART |
|
ARM
|
557 |
602 |
2.1e1 |
SMART |
|
ARM
|
607 |
647 |
1.82e-7 |
SMART |
|
Blast:ARM
|
649 |
689 |
6e-18 |
BLAST |
|
low complexity region
|
772 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
859 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
971 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1103 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1134 |
1159 |
4.4e-9 |
PFAM |
|
low complexity region
|
1197 |
1208 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1244 |
1269 |
4.1e-8 |
PFAM |
|
Pfam:SAMP
|
1323 |
1343 |
2.1e-10 |
PFAM |
|
Pfam:APC_crr
|
1369 |
1394 |
5.8e-8 |
PFAM |
|
low complexity region
|
1500 |
1516 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1540 |
1565 |
5.7e-8 |
PFAM |
|
Pfam:SAMP
|
1594 |
1613 |
8.8e-11 |
PFAM |
|
low complexity region
|
1673 |
1699 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1757 |
2093 |
1.1e-142 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000105359
AA Change: G1763E
PolyPhen 2
Score 0.109 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000100996
Gene: ENSMUSG00000020135
AA Change: G1763E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:APC_N_CC
|
30 |
81 |
2.7e-34 |
PFAM |
|
Pfam:Suppressor_APC
|
148 |
228 |
1.4e-27 |
PFAM |
|
coiled coil region
|
238 |
260 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
285 |
N/A |
INTRINSIC |
|
ARM
|
324 |
379 |
2.95e0 |
SMART |
|
ARM
|
446 |
497 |
2.22e-2 |
SMART |
|
ARM
|
499 |
540 |
3.22e0 |
SMART |
|
ARM
|
542 |
584 |
3.56e-1 |
SMART |
|
ARM
|
586 |
631 |
2.1e1 |
SMART |
|
ARM
|
636 |
676 |
1.82e-7 |
SMART |
|
Blast:ARM
|
678 |
718 |
6e-18 |
BLAST |
|
Pfam:Arm_APC_u3
|
719 |
977 |
1.1e-26 |
PFAM |
|
low complexity region
|
1000 |
1009 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1132 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1164 |
1187 |
9.3e-8 |
PFAM |
|
low complexity region
|
1226 |
1237 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1274 |
1297 |
7.9e-10 |
PFAM |
|
Pfam:APC_crr
|
1399 |
1423 |
1.3e-9 |
PFAM |
|
low complexity region
|
1529 |
1545 |
N/A |
INTRINSIC |
|
low complexity region
|
1585 |
1603 |
N/A |
INTRINSIC |
|
Pfam:SAMP
|
1624 |
1642 |
1.3e-11 |
PFAM |
|
low complexity region
|
1702 |
1728 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1786 |
2122 |
1.3e-122 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (74/74) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele display gradual postnatal growth retardation, abnormal lamination of the cerebral cortex, hippocampus, olfactory bulb and cerebellum, impaired neuronal migration and impaired coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930563M21Rik |
T |
A |
9: 55,880,992 (GRCm39) |
T146S |
unknown |
Het |
| Abca8b |
A |
T |
11: 109,840,937 (GRCm39) |
F1079I |
probably benign |
Het |
| Adcy10 |
A |
T |
1: 165,403,218 (GRCm39) |
Q1572L |
possibly damaging |
Het |
| Akna |
T |
C |
4: 63,312,846 (GRCm39) |
T426A |
possibly damaging |
Het |
| Alkbh8 |
A |
G |
9: 3,338,448 (GRCm39) |
|
probably benign |
Het |
| Bmp1 |
G |
T |
14: 70,727,613 (GRCm39) |
R657S |
possibly damaging |
Het |
| Calm1 |
G |
A |
12: 100,171,979 (GRCm39) |
|
probably null |
Het |
| Ccdc150 |
C |
A |
1: 54,311,644 (GRCm39) |
A210E |
probably damaging |
Het |
| Cdc42bpa |
T |
C |
1: 179,958,401 (GRCm39) |
I275T |
|
Het |
| Cfap54 |
G |
T |
10: 92,830,579 (GRCm39) |
Q1186K |
probably benign |
Het |
| Col6a6 |
A |
G |
9: 105,659,169 (GRCm39) |
V592A |
probably benign |
Het |
| Colec11 |
A |
T |
12: 28,644,854 (GRCm39) |
N213K |
possibly damaging |
Het |
| Dennd2b |
C |
T |
7: 109,156,291 (GRCm39) |
G153D |
probably benign |
Het |
| Dennd5b |
G |
A |
6: 148,934,844 (GRCm39) |
R676* |
probably null |
Het |
| Dnaaf5 |
T |
G |
5: 139,138,652 (GRCm39) |
Y278D |
probably damaging |
Het |
| Dop1a |
T |
A |
9: 86,371,796 (GRCm39) |
Y162* |
probably null |
Het |
| Dync1li2 |
A |
G |
8: 105,150,255 (GRCm39) |
L369P |
possibly damaging |
Het |
| Ebf1 |
A |
G |
11: 44,883,276 (GRCm39) |
T505A |
probably benign |
Het |
| Ebf1 |
A |
G |
11: 44,895,548 (GRCm39) |
I584M |
probably benign |
Het |
| Eif1ad17 |
A |
G |
12: 87,978,786 (GRCm39) |
R57G |
probably damaging |
Het |
| Frmpd1 |
T |
C |
4: 45,285,367 (GRCm39) |
L1396P |
probably damaging |
Het |
| Gart |
A |
T |
16: 91,430,904 (GRCm39) |
V386D |
possibly damaging |
Het |
| Gprin1 |
C |
T |
13: 54,885,601 (GRCm39) |
R891H |
probably damaging |
Het |
| Gsap |
G |
A |
5: 21,422,471 (GRCm39) |
V147I |
probably damaging |
Het |
| Gsc |
G |
T |
12: 104,439,120 (GRCm39) |
Y85* |
probably null |
Het |
| Gtf2a1l |
A |
G |
17: 88,976,152 (GRCm39) |
N5S |
|
Het |
| Hmcn2 |
T |
C |
2: 31,281,521 (GRCm39) |
V1912A |
possibly damaging |
Het |
| Icos |
G |
T |
1: 61,034,714 (GRCm39) |
S179I |
probably damaging |
Het |
| Ifi209 |
T |
C |
1: 173,464,969 (GRCm39) |
L33P |
probably damaging |
Het |
| Igsf10 |
A |
G |
3: 59,233,480 (GRCm39) |
I1751T |
possibly damaging |
Het |
| Il31ra |
T |
C |
13: 112,677,780 (GRCm39) |
Y252C |
probably damaging |
Het |
| Ints6 |
A |
T |
14: 62,947,036 (GRCm39) |
S310T |
probably damaging |
Het |
| Kcng1 |
A |
T |
2: 168,111,105 (GRCm39) |
S20T |
possibly damaging |
Het |
| Klf15 |
T |
C |
6: 90,444,091 (GRCm39) |
I222T |
probably damaging |
Het |
| Lmo7 |
A |
T |
14: 102,044,906 (GRCm39) |
K53* |
probably null |
Het |
| Map10 |
C |
A |
8: 126,397,649 (GRCm39) |
N347K |
probably damaging |
Het |
| Mrps11 |
C |
A |
7: 78,440,444 (GRCm39) |
T111K |
probably damaging |
Het |
| Myom3 |
T |
G |
4: 135,506,710 (GRCm39) |
D494E |
probably benign |
Het |
| Naalad2 |
T |
A |
9: 18,242,152 (GRCm39) |
Y584F |
probably damaging |
Het |
| Ndufa9 |
A |
G |
6: 126,826,050 (GRCm39) |
V9A |
probably benign |
Het |
| Nrcam |
G |
T |
12: 44,615,329 (GRCm39) |
V640F |
possibly damaging |
Het |
| Or10x4 |
C |
T |
1: 174,219,229 (GRCm39) |
T198I |
probably benign |
Het |
| Or2t48 |
C |
A |
11: 58,420,473 (GRCm39) |
G113V |
probably damaging |
Het |
| Or52d1 |
T |
C |
7: 103,755,720 (GRCm39) |
M78T |
probably benign |
Het |
| Or5ak23 |
G |
A |
2: 85,244,848 (GRCm39) |
A125V |
probably damaging |
Het |
| Pcdhga8 |
T |
A |
18: 37,860,892 (GRCm39) |
H649Q |
probably benign |
Het |
| Pdk1 |
C |
A |
2: 71,730,402 (GRCm39) |
H413Q |
probably benign |
Het |
| Pfkm |
T |
A |
15: 98,027,161 (GRCm39) |
H611Q |
probably damaging |
Het |
| Polr3g |
T |
C |
13: 81,842,535 (GRCm39) |
Y160C |
unknown |
Het |
| Ppargc1b |
A |
T |
18: 61,443,993 (GRCm39) |
M406K |
probably benign |
Het |
| Ptf1a |
C |
T |
2: 19,450,536 (GRCm39) |
|
probably benign |
Het |
| Rc3h2 |
A |
T |
2: 37,295,264 (GRCm39) |
C251S |
possibly damaging |
Het |
| Rnf32 |
A |
G |
5: 29,411,211 (GRCm39) |
T166A |
possibly damaging |
Het |
| Sav1 |
A |
T |
12: 70,022,790 (GRCm39) |
V254E |
probably damaging |
Het |
| Sel1l |
T |
C |
12: 91,797,526 (GRCm39) |
N234D |
probably benign |
Het |
| Setd1a |
C |
T |
7: 127,385,590 (GRCm39) |
P766S |
possibly damaging |
Het |
| Skida1 |
T |
A |
2: 18,050,489 (GRCm39) |
K801* |
probably null |
Het |
| Slc22a5 |
G |
A |
11: 53,774,547 (GRCm39) |
T146I |
probably benign |
Het |
| Slc25a24 |
G |
T |
3: 109,064,268 (GRCm39) |
A206S |
possibly damaging |
Het |
| Slc39a6 |
G |
A |
18: 24,733,970 (GRCm39) |
R240W |
probably damaging |
Het |
| Ssc5d |
T |
A |
7: 4,930,058 (GRCm39) |
D46E |
probably damaging |
Het |
| Tekt4 |
C |
T |
17: 25,690,901 (GRCm39) |
A69V |
possibly damaging |
Het |
| Tmigd1 |
T |
A |
11: 76,804,878 (GRCm39) |
F239Y |
probably benign |
Het |
| Tpp1 |
T |
A |
7: 105,400,846 (GRCm39) |
R60S |
probably benign |
Het |
| Trank1 |
A |
T |
9: 111,196,268 (GRCm39) |
I1431F |
probably damaging |
Het |
| Trav15-1-dv6-1 |
G |
T |
14: 53,797,519 (GRCm39) |
W56L |
probably damaging |
Het |
| Ugt2b38 |
A |
G |
5: 87,568,396 (GRCm39) |
S300P |
probably damaging |
Het |
| Urah |
T |
A |
7: 140,417,587 (GRCm39) |
L119Q |
unknown |
Het |
| Uspl1 |
T |
A |
5: 149,141,148 (GRCm39) |
F382L |
probably damaging |
Het |
| Vps9d1 |
T |
A |
8: 123,975,574 (GRCm39) |
Q157L |
probably damaging |
Het |
| Wbp1l |
G |
A |
19: 46,640,933 (GRCm39) |
V88I |
probably benign |
Het |
| Zfp444 |
T |
C |
7: 6,191,157 (GRCm39) |
S113P |
probably damaging |
Het |
| Zfp580 |
T |
G |
7: 5,056,152 (GRCm39) |
S171A |
possibly damaging |
Het |
| Zfp607a |
A |
G |
7: 27,577,382 (GRCm39) |
I151V |
probably benign |
Het |
| Zfp827 |
T |
C |
8: 79,818,564 (GRCm39) |
F614S |
probably damaging |
Het |
| Zic4 |
A |
T |
9: 91,260,913 (GRCm39) |
Q56L |
possibly damaging |
Het |
|
| Other mutations in Apc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01069:Apc2
|
APN |
10 |
80,147,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01154:Apc2
|
APN |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01411:Apc2
|
APN |
10 |
80,150,912 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01598:Apc2
|
APN |
10 |
80,148,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01621:Apc2
|
APN |
10 |
80,142,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01720:Apc2
|
APN |
10 |
80,150,333 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01837:Apc2
|
APN |
10 |
80,150,492 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01933:Apc2
|
APN |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02243:Apc2
|
APN |
10 |
80,138,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02292:Apc2
|
APN |
10 |
80,138,258 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02956:Apc2
|
APN |
10 |
80,142,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03081:Apc2
|
APN |
10 |
80,148,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03172:Apc2
|
APN |
10 |
80,149,220 (GRCm39) |
missense |
probably damaging |
0.98 |
|
LCD18:Apc2
|
UTSW |
10 |
80,135,808 (GRCm39) |
intron |
probably benign |
|
|
R0278:Apc2
|
UTSW |
10 |
80,148,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0501:Apc2
|
UTSW |
10 |
80,150,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Apc2
|
UTSW |
10 |
80,142,090 (GRCm39) |
nonsense |
probably null |
|
|
R0607:Apc2
|
UTSW |
10 |
80,149,935 (GRCm39) |
missense |
probably benign |
|
|
R0624:Apc2
|
UTSW |
10 |
80,150,417 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0633:Apc2
|
UTSW |
10 |
80,143,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Apc2
|
UTSW |
10 |
80,140,801 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0647:Apc2
|
UTSW |
10 |
80,140,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0830:Apc2
|
UTSW |
10 |
80,151,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1071:Apc2
|
UTSW |
10 |
80,147,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1221:Apc2
|
UTSW |
10 |
80,142,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Apc2
|
UTSW |
10 |
80,148,183 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1579:Apc2
|
UTSW |
10 |
80,147,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Apc2
|
UTSW |
10 |
80,137,676 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1700:Apc2
|
UTSW |
10 |
80,148,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1774:Apc2
|
UTSW |
10 |
80,144,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Apc2
|
UTSW |
10 |
80,149,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1908:Apc2
|
UTSW |
10 |
80,150,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1915:Apc2
|
UTSW |
10 |
80,151,701 (GRCm39) |
missense |
probably benign |
|
|
R1999:Apc2
|
UTSW |
10 |
80,144,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2050:Apc2
|
UTSW |
10 |
80,143,443 (GRCm39) |
splice site |
probably null |
|
|
R2219:Apc2
|
UTSW |
10 |
80,144,943 (GRCm39) |
missense |
probably benign |
0.41 |
|
R2393:Apc2
|
UTSW |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3862:Apc2
|
UTSW |
10 |
80,143,393 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3900:Apc2
|
UTSW |
10 |
80,131,806 (GRCm39) |
splice site |
probably null |
|
|
R3901:Apc2
|
UTSW |
10 |
80,150,922 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3952:Apc2
|
UTSW |
10 |
80,150,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4009:Apc2
|
UTSW |
10 |
80,149,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4090:Apc2
|
UTSW |
10 |
80,141,378 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4695:Apc2
|
UTSW |
10 |
80,146,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4754:Apc2
|
UTSW |
10 |
80,150,192 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Apc2
|
UTSW |
10 |
80,150,196 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4886:Apc2
|
UTSW |
10 |
80,150,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4964:Apc2
|
UTSW |
10 |
80,149,841 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5056:Apc2
|
UTSW |
10 |
80,137,148 (GRCm39) |
missense |
probably benign |
|
|
R5057:Apc2
|
UTSW |
10 |
80,144,903 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5165:Apc2
|
UTSW |
10 |
80,151,684 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5241:Apc2
|
UTSW |
10 |
80,148,068 (GRCm39) |
missense |
probably benign |
|
|
R5649:Apc2
|
UTSW |
10 |
80,149,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Apc2
|
UTSW |
10 |
80,147,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6124:Apc2
|
UTSW |
10 |
80,142,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6218:Apc2
|
UTSW |
10 |
80,142,254 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6376:Apc2
|
UTSW |
10 |
80,148,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Apc2
|
UTSW |
10 |
80,149,757 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6572:Apc2
|
UTSW |
10 |
80,147,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6620:Apc2
|
UTSW |
10 |
80,149,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7171:Apc2
|
UTSW |
10 |
80,151,170 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7180:Apc2
|
UTSW |
10 |
80,146,990 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7326:Apc2
|
UTSW |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Apc2
|
UTSW |
10 |
80,149,316 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7378:Apc2
|
UTSW |
10 |
80,147,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7384:Apc2
|
UTSW |
10 |
80,148,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7431:Apc2
|
UTSW |
10 |
80,138,017 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7543:Apc2
|
UTSW |
10 |
80,150,720 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7743:Apc2
|
UTSW |
10 |
80,140,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7759:Apc2
|
UTSW |
10 |
80,147,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Apc2
|
UTSW |
10 |
80,151,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8327:Apc2
|
UTSW |
10 |
80,137,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8489:Apc2
|
UTSW |
10 |
80,143,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Apc2
|
UTSW |
10 |
80,150,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8669:Apc2
|
UTSW |
10 |
80,149,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8773:Apc2
|
UTSW |
10 |
80,142,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8920:Apc2
|
UTSW |
10 |
80,149,934 (GRCm39) |
missense |
probably benign |
|
|
R9224:Apc2
|
UTSW |
10 |
80,150,111 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9357:Apc2
|
UTSW |
10 |
80,146,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Apc2
|
UTSW |
10 |
80,145,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9666:Apc2
|
UTSW |
10 |
80,147,183 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9689:Apc2
|
UTSW |
10 |
80,150,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Apc2
|
UTSW |
10 |
80,148,098 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Apc2
|
UTSW |
10 |
80,147,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGCAAACTCCATTGTCACATG -3'
(R):5'- AGTGGTACCAGATGTCCCTG -3'
Sequencing Primer
(F):5'- CATTGTCACATGGCTGCATCAGG -3'
(R):5'- GGTACCAGATGTCCCTGTCTTCTTAG -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation