Mutagenetix > Incidental Mutation

Incidental Mutation 'R9180:Fcgbp'

696956

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9180 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

28071236-28120862 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to T at 28103773 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Stop codon at position 1601 (E1601*)

Ref Sequence

ENSEMBL: ENSMUSP00000075945 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

probably null
Transcript: ENSMUST00000076648
AA Change: E1601*

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: E1601*

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000138392
AA Change: E1601*

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: E1601*

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 77 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930579F01Rik	G	A	3: 138,183,709 (GRCm38)	P49L	probably benign	Het
Adam34l	T	A	8: 43,626,933 (GRCm38)	R85*	probably null	Het
Anapc2	C	T	2: 25,273,291 (GRCm38)	T180I	probably benign	Het
Ankib1	A	T	5: 3,706,276 (GRCm38)	H556Q	probably damaging	Het
Aox2	A	T	1: 58,339,618 (GRCm38)	K1009*	probably null	Het
Apob	C	T	12: 7,997,925 (GRCm38)	P968L	probably damaging	Het
Bpi	T	A	2: 158,274,688 (GRCm38)	F335Y	probably benign	Het
Cabcoco1	T	C	10: 68,436,889 (GRCm38)	Y222C	probably damaging	Het
Camk2b	G	T	11: 5,989,332 (GRCm38)	C273*	probably null	Het
Catsperd	G	A	17: 56,661,252 (GRCm38)	D546N	probably benign	Het
Cenpb	C	T	2: 131,179,543 (GRCm38)	G112S	probably damaging	Het
Col6a5	A	G	9: 105,861,979 (GRCm38)	L2585P	probably damaging	Het
Cop1	A	G	1: 159,319,769 (GRCm38)	E555G	probably damaging	Het
Coro1b	T	C	19: 4,153,393 (GRCm38)	V411A	probably benign	Het
Cyfip2	G	A	11: 46,286,093 (GRCm38)	R87C	probably damaging	Het
Dthd1	A	C	5: 62,888,067 (GRCm38)	I725L	probably benign	Het
Dydc1	A	C	14: 41,078,097 (GRCm38)	E20A	probably damaging	Het
Ermp1	T	C	19: 29,632,445 (GRCm38)	I317V	probably benign	Het
Fat4	A	G	3: 38,888,407 (GRCm38)	N483S	possibly damaging	Het
Fbxo33	A	G	12: 59,204,309 (GRCm38)		probably null	Het
Fer1l5	A	T	1: 36,410,918 (GRCm38)	S1118C	probably null	Het
Fer1l6	T	C	15: 58,622,381 (GRCm38)	V1141A	probably benign	Het
Flnb	C	T	14: 7,818,219 (GRCm38)	T23M	probably damaging	Het
Fsip2	T	C	2: 82,985,230 (GRCm38)	L3769P	possibly damaging	Het
Gna11	T	C	10: 81,535,108 (GRCm38)	K98R		Het
Gpat3	A	T	5: 100,884,364 (GRCm38)	T176S	probably benign	Het
Gprc5b	A	G	7: 118,984,319 (GRCm38)	L109P	probably damaging	Het
Hadha	A	T	5: 30,135,040 (GRCm38)	N246K	probably benign	Het
Haus3	G	A	5: 34,167,491 (GRCm38)	Q275*	probably null	Het
Higd1b	A	G	11: 102,837,264 (GRCm38)	Y44C	possibly damaging	Het
Igkv1-131	T	C	6: 67,766,234 (GRCm38)	K55R	probably benign	Het
Igtp	G	T	11: 58,207,265 (GRCm38)	E421*	probably null	Het
Kcnk3	G	T	5: 30,588,188 (GRCm38)		probably benign	Het
Krtap4-13	A	T	11: 99,809,339 (GRCm38)	C165S	unknown	Het
Lrfn4	T	C	19: 4,613,325 (GRCm38)	R394G	probably benign	Het
Lrrc7	A	C	3: 158,161,374 (GRCm38)	L910R	possibly damaging	Het
Mbtd1	A	G	11: 93,932,392 (GRCm38)	D568G	probably damaging	Het
Mettl16	T	A	11: 74,803,000 (GRCm38)	I279N	probably benign	Het
Mmrn2	A	G	14: 34,399,201 (GRCm38)	H676R	probably benign	Het
Mrgprg	T	C	7: 143,764,613 (GRCm38)	K254R	probably benign	Het
Muc16	A	C	9: 18,642,742 (GRCm38)	V4085G	unknown	Het
Mvp	T	C	7: 126,992,650 (GRCm38)	Q456R	probably benign	Het
Myf6	T	C	10: 107,493,457 (GRCm38)	D209G	probably benign	Het
Ociad1	A	G	5: 73,310,382 (GRCm38)	D167G	probably benign	Het
Or11l3	A	G	11: 58,625,236 (GRCm38)	L270P	probably benign	Het
Or1l4	A	G	2: 37,201,280 (GRCm38)	D13G	probably benign	Het
Or51f23b	T	A	7: 102,753,527 (GRCm38)	Y134F	probably damaging	Het
Or5m3	T	G	2: 86,007,981 (GRCm38)	D68E	probably damaging	Het
Or6c1b	T	C	10: 129,436,989 (GRCm38)	F59S	probably damaging	Het
Phf20	A	G	2: 156,272,617 (GRCm38)	D295G	probably benign	Het
Pkd1l3	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	8: 109,624,195 (GRCm38)		probably benign	Het
Ppp1r13b	A	T	12: 111,844,982 (GRCm38)	H157Q	probably benign	Het
Prss3b	A	G	6: 41,031,747 (GRCm38)	L211P	probably damaging	Het
Rbm26	C	T	14: 105,153,603 (GRCm38)	R149H	unknown	Het
Reg3d	C	T	6: 78,378,460 (GRCm38)	C16Y	possibly damaging	Het
Rrp36	A	G	17: 46,668,054 (GRCm38)	F193L	possibly damaging	Het
Rtca	A	T	3: 116,489,256 (GRCm38)	M361K	probably benign	Het
Ryr3	T	G	2: 112,661,636 (GRCm38)	D3790A	probably damaging	Het
Serpina3n	C	A	12: 104,411,181 (GRCm38)	A231E	probably benign	Het
Sh2d2a	A	G	3: 87,851,763 (GRCm38)	D224G	possibly damaging	Het
Sh3bp2	A	T	5: 34,561,033 (GRCm38)	K526*	probably null	Het
Slc12a2	A	G	18: 57,936,397 (GRCm38)	T1017A	possibly damaging	Het
Slc12a8	T	C	16: 33,541,027 (GRCm38)	L93P	probably damaging	Het
Slc5a6	A	G	5: 31,037,846 (GRCm38)	I469T	probably damaging	Het
Smarcc1	T	A	9: 110,135,660 (GRCm38)	V95D	probably damaging	Het
Snap29	T	A	16: 17,406,299 (GRCm38)	S59R	probably damaging	Het
Tmem121b	T	A	6: 120,492,823 (GRCm38)	Y311F	probably damaging	Het
Tpcn1	C	A	5: 120,555,935 (GRCm38)	V199L	probably benign	Het
Ttn	T	C	2: 76,788,377 (GRCm38)	I16188V	probably benign	Het
Usp24	T	C	4: 106,359,050 (GRCm38)	I366T	possibly damaging	Het
Utrn	T	A	10: 12,669,719 (GRCm38)	E1727D	probably damaging	Het
Vav2	T	C	2: 27,292,689 (GRCm38)	D301G	probably damaging	Het
Vmn2r104	T	C	17: 20,042,825 (GRCm38)	T125A	probably benign	Het
Vmn2r73	T	G	7: 85,857,915 (GRCm38)	I730L	probably benign	Het
Zfp352	A	T	4: 90,224,881 (GRCm38)	K419N	probably benign	Het
Zfp84	C	A	7: 29,775,448 (GRCm38)	S48R	probably damaging	Het
Zfp947	A	T	17: 22,145,405 (GRCm38)	H429Q	probably damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	28,085,130 (GRCm38)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	28,101,541 (GRCm38)	splice site	probably benign
IGL00335:Fcgbp	APN	7	28,086,135 (GRCm38)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	28,075,086 (GRCm38)	nonsense	probably null
IGL00491:Fcgbp	APN	7	28,093,402 (GRCm38)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	28,091,797 (GRCm38)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	28,089,647 (GRCm38)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	28,093,642 (GRCm38)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	28,103,963 (GRCm38)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	28,106,374 (GRCm38)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	28,075,204 (GRCm38)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	28,091,954 (GRCm38)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	28,075,235 (GRCm38)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	28,071,643 (GRCm38)	splice site	probably benign
IGL02377:Fcgbp	APN	7	28,106,970 (GRCm38)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	28,075,171 (GRCm38)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	28,089,953 (GRCm38)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	28,104,732 (GRCm38)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	28,101,174 (GRCm38)	intron	probably benign
IGL02631:Fcgbp	APN	7	28,085,298 (GRCm38)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	28,101,434 (GRCm38)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	28,117,358 (GRCm38)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	28,091,847 (GRCm38)	nonsense	probably null
IGL02971:Fcgbp	APN	7	28,101,473 (GRCm38)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	28,085,432 (GRCm38)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	28,089,917 (GRCm38)	missense	possibly damaging	0.76
bilge	UTSW	7	28,117,337 (GRCm38)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	28,091,918 (GRCm38)	missense	probably benign	0.00
swill	UTSW	7	28,089,734 (GRCm38)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	28,107,356 (GRCm38)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	28,101,151 (GRCm38)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	28,075,273 (GRCm38)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	28,085,493 (GRCm38)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	28,091,454 (GRCm38)	splice site	probably benign
R0586:Fcgbp	UTSW	7	28,089,713 (GRCm38)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	28,085,110 (GRCm38)	nonsense	probably null
R0987:Fcgbp	UTSW	7	28,094,174 (GRCm38)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	28,120,525 (GRCm38)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	28,093,379 (GRCm38)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	28,093,379 (GRCm38)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	28,103,733 (GRCm38)	nonsense	probably null
R1474:Fcgbp	UTSW	7	28,091,848 (GRCm38)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	28,075,160 (GRCm38)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	28,101,249 (GRCm38)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	28,093,443 (GRCm38)	nonsense	probably null
R1772:Fcgbp	UTSW	7	28,105,175 (GRCm38)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	28,086,139 (GRCm38)	missense	probably benign
R1808:Fcgbp	UTSW	7	28,085,090 (GRCm38)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	28,085,283 (GRCm38)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	28,107,093 (GRCm38)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	28,094,192 (GRCm38)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	28,120,360 (GRCm38)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	28,120,389 (GRCm38)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	28,120,389 (GRCm38)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	28,092,019 (GRCm38)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	28,107,203 (GRCm38)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	28,075,413 (GRCm38)	splice site	probably benign
R3037:Fcgbp	UTSW	7	28,102,702 (GRCm38)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	28,117,240 (GRCm38)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	28,101,276 (GRCm38)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	28,085,457 (GRCm38)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	28,075,399 (GRCm38)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	28,075,399 (GRCm38)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	28,104,116 (GRCm38)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	28,104,116 (GRCm38)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	28,107,296 (GRCm38)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	28,094,961 (GRCm38)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	28,094,961 (GRCm38)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	28,094,937 (GRCm38)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	28,113,958 (GRCm38)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	28,086,344 (GRCm38)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	28,086,235 (GRCm38)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	28,089,812 (GRCm38)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	28,117,570 (GRCm38)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	28,086,103 (GRCm38)	splice site	probably null
R5219:Fcgbp	UTSW	7	28,104,085 (GRCm38)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	28,085,199 (GRCm38)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	28,093,674 (GRCm38)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	28,091,818 (GRCm38)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	28,089,734 (GRCm38)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	28,105,055 (GRCm38)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	28,085,313 (GRCm38)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	28,093,635 (GRCm38)	missense	probably benign
R5583:Fcgbp	UTSW	7	28,091,579 (GRCm38)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	28,092,022 (GRCm38)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	28,085,218 (GRCm38)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	28,101,494 (GRCm38)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	28,085,503 (GRCm38)	splice site	probably benign
R5936:Fcgbp	UTSW	7	28,086,692 (GRCm38)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	28,120,534 (GRCm38)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	28,104,965 (GRCm38)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	28,107,008 (GRCm38)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	28,093,538 (GRCm38)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	28,091,918 (GRCm38)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	28,086,270 (GRCm38)	nonsense	probably null
R6711:Fcgbp	UTSW	7	28,089,673 (GRCm38)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	28,103,212 (GRCm38)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	28,107,356 (GRCm38)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	28,085,018 (GRCm38)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	28,089,704 (GRCm38)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	28,093,823 (GRCm38)	missense	probably benign
R6943:Fcgbp	UTSW	7	28,092,052 (GRCm38)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	28,091,933 (GRCm38)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	28,084,962 (GRCm38)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	28,104,021 (GRCm38)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	28,101,392 (GRCm38)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	28,093,436 (GRCm38)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	28,101,507 (GRCm38)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	28,086,524 (GRCm38)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	28,107,285 (GRCm38)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	28,102,976 (GRCm38)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	28,089,674 (GRCm38)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	28,085,369 (GRCm38)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	28,086,299 (GRCm38)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	28,102,966 (GRCm38)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	28,091,503 (GRCm38)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	28,085,035 (GRCm38)	nonsense	probably null
R7820:Fcgbp	UTSW	7	28,120,359 (GRCm38)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	28,106,979 (GRCm38)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	28,117,207 (GRCm38)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	28,104,170 (GRCm38)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	28,113,964 (GRCm38)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	28,105,071 (GRCm38)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	28,085,082 (GRCm38)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	28,085,494 (GRCm38)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	28,091,749 (GRCm38)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	28,104,851 (GRCm38)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	28,086,344 (GRCm38)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	28,094,189 (GRCm38)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	28,117,337 (GRCm38)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	28,107,390 (GRCm38)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	28,089,806 (GRCm38)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	28,105,010 (GRCm38)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	28,086,553 (GRCm38)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	28,120,495 (GRCm38)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	28,106,196 (GRCm38)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	28,084,987 (GRCm38)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	28,086,509 (GRCm38)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	28,091,483 (GRCm38)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	28,091,852 (GRCm38)	missense	probably damaging	1.00
R9262:Fcgbp	UTSW	7	28,120,527 (GRCm38)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	28,104,011 (GRCm38)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	28,091,512 (GRCm38)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	28,103,138 (GRCm38)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	28,101,407 (GRCm38)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	28,106,975 (GRCm38)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	28,093,575 (GRCm38)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	28,103,587 (GRCm38)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	28,089,755 (GRCm38)	missense	probably benign
X0028:Fcgbp	UTSW	7	28,104,020 (GRCm38)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	28,091,647 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,089,755 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,086,191 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,103,884 (GRCm38)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	28,093,345 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AGCCACTATGAGCTCTGTGG -3'
(R):5'- AAGTCAAACCGGTGCCCATC -3'

Sequencing Primer
(F):5'- ACTATGAGCTCTGTGGCCCAC -3'
(R):5'- CCATCTAGGGTGGTGTAATGG -3'

Posted On

2022-02-07