Mutagenetix > Incidental Mutation

Incidental Mutation 'R9182:Hmcn1'

697055

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

LOC240793, EG545370

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9182 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

150562524-150993435 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to A at 150624586 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Stop codon at position 3952 (E3952*)

Ref Sequence

ENSEMBL: ENSMUSP00000074340 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000074783
AA Change: E3952*

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: E3952*

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000137197
AA Change: E3952*

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: E3952*

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.5%

Validation Efficiency

100% (99/99)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 101 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2900026A02Rik	A	T	5: 113,095,607 (GRCm38)	M190K	probably damaging	Het
4931406B18Rik	A	G	7: 43,504,216 (GRCm38)	W3R	probably damaging	Het
Acap3	T	C	4: 155,905,435 (GRCm38)	L720P	probably damaging	Het
Actc1	T	C	2: 114,052,013 (GRCm38)	T7A	probably benign	Het
Angpt2	T	A	8: 18,710,642 (GRCm38)		probably null	Het
Babam2	T	A	5: 31,901,057 (GRCm38)	D228E	possibly damaging	Het
Ccar1	G	A	10: 62,785,568 (GRCm38)	L34F	probably damaging	Het
Ccdc83	T	C	7: 90,236,894 (GRCm38)	D219G	probably damaging	Het
Cct2	A	G	10: 117,056,120 (GRCm38)	V341A	probably benign	Het
Cdc20b	G	A	13: 113,071,969 (GRCm38)		probably null	Het
Chd7	T	A	4: 8,838,737 (GRCm38)	L1312Q	probably damaging	Het
Cltc	G	A	11: 86,705,156 (GRCm38)	T1252I	probably damaging	Het
Cnpy1	G	T	5: 28,245,801 (GRCm38)	D2E	possibly damaging	Het
Crat	C	T	2: 30,408,073 (GRCm38)	V205M	probably damaging	Het
Cspg4b	A	G	13: 113,320,824 (GRCm38)	N1135D		Het
Dgkb	T	C	12: 38,166,777 (GRCm38)		probably null	Het
Dglucy	T	C	12: 100,844,769 (GRCm38)	V254A	possibly damaging	Het
Disp3	A	G	4: 148,270,384 (GRCm38)	S392P	probably damaging	Het
Dlx6	A	T	6: 6,863,456 (GRCm38)	Q26L	probably benign	Het
Dnah3	T	C	7: 120,085,128 (GRCm38)	D258G	probably damaging	Het
Dnah6	A	T	6: 73,144,705 (GRCm38)	Y1431*	probably null	Het
Dnah7b	T	C	1: 46,290,878 (GRCm38)	I3294T	probably benign	Het
Dnai2	A	G	11: 114,733,013 (GRCm38)	N34S	probably benign	Het
Dock2	T	C	11: 34,310,398 (GRCm38)	K981R	possibly damaging	Het
Entpd8	T	C	2: 25,081,919 (GRCm38)	I33T	probably benign	Het
Eppk1	A	G	15: 76,111,253 (GRCm38)	L476P	probably benign	Het
Etv1	T	A	12: 38,780,717 (GRCm38)		probably null	Het
Fads2b	T	C	2: 85,500,237 (GRCm38)	H242R	probably benign	Het
Fam193a	T	A	5: 34,466,017 (GRCm38)	N1316K	possibly damaging	Het
Fkbp4	T	C	6: 128,438,419 (GRCm38)	E31G	probably benign	Het
Fnbp1l	C	T	3: 122,569,696 (GRCm38)	D81N	probably damaging	Het
Fstl4	T	C	11: 53,134,078 (GRCm38)	V259A	probably damaging	Het
Glipr1l1	T	C	10: 112,076,151 (GRCm38)	S197P	probably damaging	Het
Gprin3	A	T	6: 59,354,212 (GRCm38)	M370K	probably benign	Het
Gsc	G	T	12: 104,472,861 (GRCm38)	Y85*	probably null	Het
Gys2	T	G	6: 142,446,009 (GRCm38)	Y509S	probably damaging	Het
Gys2	T	C	6: 142,461,252 (GRCm38)	N126S	possibly damaging	Het
Hsd3b9	C	T	3: 98,446,689 (GRCm38)	A165T	possibly damaging	Het
Htr1f	T	C	16: 64,926,462 (GRCm38)	M156V	probably benign	Het
Il21r	G	A	7: 125,629,041 (GRCm38)	G228E	probably benign	Het
Kat6b	C	T	14: 21,517,119 (GRCm38)	S82L	probably benign	Het
Kntc1	T	A	5: 123,802,292 (GRCm38)	L1651Q	probably damaging	Het
Lipi	G	T	16: 75,560,785 (GRCm38)	Y297*	probably null	Het
Mapre3	T	C	5: 30,864,672 (GRCm38)	S190P	possibly damaging	Het
Mmp8	T	A	9: 7,567,466 (GRCm38)	Y442*	probably null	Het
Mmut	A	G	17: 40,941,419 (GRCm38)	E284G	probably damaging	Het
Mt3	G	A	8: 94,153,987 (GRCm38)	E62K	unknown	Het
Myh13	A	G	11: 67,337,753 (GRCm38)	E373G	probably damaging	Het
Myh7	T	C	14: 54,988,917 (GRCm38)	Y422C	probably damaging	Het
Nalcn	A	G	14: 123,596,604 (GRCm38)	V53A	probably damaging	Het
Nucb2	A	G	7: 116,521,835 (GRCm38)		probably null	Het
Opn5	A	T	17: 42,592,999 (GRCm38)	H148Q	probably damaging	Het
Or13a23-ps1	A	T	7: 140,538,869 (GRCm38)	L117F	probably benign	Het
Or51h1	A	T	7: 102,659,720 (GRCm38)	I300L	probably damaging	Het
Or51v14	T	C	7: 103,611,856 (GRCm38)	K166E	possibly damaging	Het
Or6b1	A	T	6: 42,838,076 (GRCm38)	N65I	probably benign	Het
Or7g16	G	T	9: 18,815,446 (GRCm38)	Q283K	probably damaging	Het
Or8b56	C	A	9: 38,827,876 (GRCm38)	H56N	probably damaging	Het
Osmr	T	A	15: 6,821,088 (GRCm38)	D679V	probably damaging	Het
Pde4dip	T	C	3: 97,694,998 (GRCm38)	D2305G	probably benign	Het
Pdgfrl	A	T	8: 40,976,959 (GRCm38)	Q121L	probably damaging	Het
Pls1	C	A	9: 95,776,758 (GRCm38)	V226F	probably damaging	Het
Plxnd1	T	A	6: 115,993,785 (GRCm38)	I341F	probably damaging	Het
Ppfia2	T	A	10: 106,927,779 (GRCm38)	M1211K	probably benign	Het
Ppfibp2	T	A	7: 107,708,846 (GRCm38)	Y229N	possibly damaging	Het
Prss53	A	G	7: 127,888,382 (GRCm38)	S266P	probably benign	Het
Pycr2	C	T	1: 180,906,832 (GRCm38)	Q226*	probably null	Het
Rad50	T	C	11: 53,692,763 (GRCm38)	H397R	probably benign	Het
Raf1	T	C	6: 115,623,479 (GRCm38)	E393G	probably damaging	Het
Reln	T	C	5: 21,901,619 (GRCm38)	D3251G	probably benign	Het
Robo4	A	T	9: 37,401,910 (GRCm38)		probably benign	Het
Sbf1	A	T	15: 89,289,603 (GRCm38)		probably null	Het
Serpinb6a	T	C	13: 33,925,377 (GRCm38)	D145G	probably damaging	Het
Setx	T	A	2: 29,171,287 (GRCm38)	M2236K	probably damaging	Het
Sgms1	A	G	19: 32,124,358 (GRCm38)	V416A	probably benign	Het
Six5	T	G	7: 19,097,007 (GRCm38)	S520A	probably benign	Het
Sox5	T	A	6: 143,833,392 (GRCm38)	I722F	possibly damaging	Het
Spag17	T	G	3: 100,058,842 (GRCm38)	I1147S	possibly damaging	Het
Spice1	C	T	16: 44,385,702 (GRCm38)	T842I	possibly damaging	Het
Ssbp2	A	G	13: 91,700,681 (GRCm38)	T358A	probably damaging	Het
Taok3	T	C	5: 117,217,242 (GRCm38)		probably null	Het
Tbc1d2b	C	A	9: 90,270,599 (GRCm38)	C38F	probably damaging	Het
Tecrl	C	A	5: 83,309,202 (GRCm38)		probably null	Het
Tgm7	T	C	2: 121,096,499 (GRCm38)	N390D	probably benign	Het
Thsd4	T	G	9: 59,987,366 (GRCm38)	M770L	probably benign	Het
Tmod2	C	A	9: 75,597,342 (GRCm38)		probably benign	Het
Tnks	A	G	8: 34,841,751 (GRCm38)		probably null	Het
Tox3	T	C	8: 90,257,879 (GRCm38)	N224S	probably benign	Het
Trappc10	C	T	10: 78,214,630 (GRCm38)	E326K	probably damaging	Het
Usp16	T	A	16: 87,479,654 (GRCm38)	F627I	probably benign	Het
Vcam1	T	C	3: 116,117,355 (GRCm38)	I465V	probably benign	Het
Vmn1r128	T	C	7: 21,349,758 (GRCm38)	I129T	possibly damaging	Het
Vmn1r217	T	A	13: 23,114,325 (GRCm38)	I136L	probably benign	Het
Vmn2r2	A	T	3: 64,137,381 (GRCm38)	C115S	probably damaging	Het
Vmn2r85	A	C	10: 130,429,481 (GRCm38)	S44R	probably benign	Het
Wasf3	T	A	5: 146,466,825 (GRCm38)	Y248*	probably null	Het
Yipf5	A	T	18: 40,210,798 (GRCm38)	L127M	probably damaging	Het
Zbp1	G	T	2: 173,209,140 (GRCm38)	C312*	probably null	Het
Zfp423	A	T	8: 87,782,114 (GRCm38)	F534Y	probably damaging	Het
Zfp69	T	G	4: 120,935,111 (GRCm38)	Y156S	probably damaging	Het
Zmat4	A	G	8: 23,929,210 (GRCm38)	N155S	probably damaging	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,677,278 (GRCm38)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,638,999 (GRCm38)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,806,366 (GRCm38)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,664,936 (GRCm38)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,656,734 (GRCm38)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,630,340 (GRCm38)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,610,713 (GRCm38)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,605,006 (GRCm38)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,582,301 (GRCm38)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,638,869 (GRCm38)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,627,033 (GRCm38)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,632,552 (GRCm38)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,622,924 (GRCm38)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,745,001 (GRCm38)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,719,240 (GRCm38)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,593,097 (GRCm38)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,859,239 (GRCm38)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,605,072 (GRCm38)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,609,631 (GRCm38)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,598,397 (GRCm38)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,627,413 (GRCm38)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,672,032 (GRCm38)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,580,233 (GRCm38)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,737,299 (GRCm38)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,583,280 (GRCm38)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,744,960 (GRCm38)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,672,038 (GRCm38)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,615,300 (GRCm38)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,690,601 (GRCm38)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,742,260 (GRCm38)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,667,887 (GRCm38)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,732,892 (GRCm38)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,603,871 (GRCm38)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,615,298 (GRCm38)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,704,181 (GRCm38)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,630,728 (GRCm38)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,722,607 (GRCm38)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,563,598 (GRCm38)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,806,401 (GRCm38)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,664,915 (GRCm38)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,802,897 (GRCm38)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,722,424 (GRCm38)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,993,023 (GRCm38)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,809,726 (GRCm38)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,697,493 (GRCm38)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,744,995 (GRCm38)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,619,009 (GRCm38)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,604,903 (GRCm38)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,656,694 (GRCm38)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,646,832 (GRCm38)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,563,828 (GRCm38)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,675,974 (GRCm38)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,577,278 (GRCm38)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,657,207 (GRCm38)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,697,522 (GRCm38)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,671,917 (GRCm38)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,808,539 (GRCm38)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,802,909 (GRCm38)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,743,667 (GRCm38)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,770,352 (GRCm38)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,772,510 (GRCm38)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,598,424 (GRCm38)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,630,231 (GRCm38)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,732,910 (GRCm38)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,701,969 (GRCm38)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,663,872 (GRCm38)	missense	probably damaging	1.00
Backbone	UTSW	1	150,622,994 (GRCm38)	missense	probably benign	0.09
Cambrian	UTSW	1	150,732,846 (GRCm38)	missense	probably damaging	1.00
chordate	UTSW	1	150,587,015 (GRCm38)	missense	probably benign	0.00
Justamere	UTSW	1	150,588,257 (GRCm38)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,675,540 (GRCm38)	missense	probably benign	0.00
notochord	UTSW	1	150,770,293 (GRCm38)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,732,946 (GRCm38)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,609,775 (GRCm38)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,609,775 (GRCm38)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,738,658 (GRCm38)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,720,689 (GRCm38)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,808,737 (GRCm38)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,669,487 (GRCm38)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,808,676 (GRCm38)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,652,551 (GRCm38)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,677,406 (GRCm38)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,587,015 (GRCm38)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,808,647 (GRCm38)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,677,324 (GRCm38)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,663,879 (GRCm38)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,603,811 (GRCm38)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,798,814 (GRCm38)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,715,822 (GRCm38)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,732,792 (GRCm38)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,859,252 (GRCm38)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,876,419 (GRCm38)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,742,341 (GRCm38)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,719,117 (GRCm38)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,650,017 (GRCm38)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,609,801 (GRCm38)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,657,376 (GRCm38)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,594,016 (GRCm38)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,798,719 (GRCm38)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,819,410 (GRCm38)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,808,787 (GRCm38)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,753,665 (GRCm38)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,650,073 (GRCm38)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,679,607 (GRCm38)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,577,377 (GRCm38)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,689,590 (GRCm38)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,618,928 (GRCm38)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,618,928 (GRCm38)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,679,607 (GRCm38)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,679,607 (GRCm38)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,749,026 (GRCm38)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,753,654 (GRCm38)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,748,191 (GRCm38)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,586,468 (GRCm38)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,680,715 (GRCm38)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,646,794 (GRCm38)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,652,506 (GRCm38)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,609,700 (GRCm38)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,689,590 (GRCm38)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,689,590 (GRCm38)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,772,552 (GRCm38)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,669,421 (GRCm38)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,773,803 (GRCm38)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,734,532 (GRCm38)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,657,241 (GRCm38)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,745,027 (GRCm38)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,669,558 (GRCm38)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,630,333 (GRCm38)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,565,369 (GRCm38)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,675,984 (GRCm38)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,859,186 (GRCm38)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,586,468 (GRCm38)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,599,030 (GRCm38)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,563,568 (GRCm38)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,749,083 (GRCm38)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,627,152 (GRCm38)	missense	probably damaging	0.98
R1794:Hmcn1	UTSW	1	150,598,285 (GRCm38)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,721,664 (GRCm38)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,657,193 (GRCm38)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,603,812 (GRCm38)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,720,695 (GRCm38)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,577,295 (GRCm38)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,819,500 (GRCm38)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,819,500 (GRCm38)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,657,451 (GRCm38)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,992,855 (GRCm38)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,604,882 (GRCm38)	missense	probably benign	0.28
R1959:Hmcn1	UTSW	1	150,649,676 (GRCm38)	missense	probably benign	0.00
R1960:Hmcn1	UTSW	1	150,677,376 (GRCm38)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,675,991 (GRCm38)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,738,613 (GRCm38)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,677,334 (GRCm38)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,577,323 (GRCm38)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,633,659 (GRCm38)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,715,815 (GRCm38)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,599,010 (GRCm38)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,624,598 (GRCm38)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,704,226 (GRCm38)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,652,678 (GRCm38)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,622,934 (GRCm38)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,565,384 (GRCm38)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,860,341 (GRCm38)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,599,032 (GRCm38)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,615,221 (GRCm38)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,686,867 (GRCm38)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,773,820 (GRCm38)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,743,647 (GRCm38)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,652,575 (GRCm38)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,630,652 (GRCm38)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,563,599 (GRCm38)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,563,599 (GRCm38)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,802,873 (GRCm38)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,749,035 (GRCm38)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,605,102 (GRCm38)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,605,102 (GRCm38)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,689,518 (GRCm38)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,745,025 (GRCm38)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,802,824 (GRCm38)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,622,994 (GRCm38)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,586,418 (GRCm38)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,649,577 (GRCm38)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,586,965 (GRCm38)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,635,195 (GRCm38)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,635,195 (GRCm38)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,635,195 (GRCm38)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,690,610 (GRCm38)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,573,569 (GRCm38)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,722,453 (GRCm38)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,722,369 (GRCm38)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,772,502 (GRCm38)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,703,216 (GRCm38)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,658,508 (GRCm38)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,595,999 (GRCm38)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,657,459 (GRCm38)	missense	probably null
R4493:Hmcn1	UTSW	1	150,701,899 (GRCm38)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,633,666 (GRCm38)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,563,780 (GRCm38)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,734,487 (GRCm38)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,738,645 (GRCm38)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,595,894 (GRCm38)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,675,511 (GRCm38)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,624,550 (GRCm38)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,619,065 (GRCm38)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,772,571 (GRCm38)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,694,833 (GRCm38)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,689,595 (GRCm38)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,577,612 (GRCm38)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,753,611 (GRCm38)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,753,611 (GRCm38)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,593,085 (GRCm38)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,677,379 (GRCm38)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,722,535 (GRCm38)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,876,360 (GRCm38)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,657,470 (GRCm38)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,819,449 (GRCm38)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,680,688 (GRCm38)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,588,257 (GRCm38)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,737,256 (GRCm38)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,610,669 (GRCm38)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,656,741 (GRCm38)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,646,701 (GRCm38)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,595,861 (GRCm38)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,679,514 (GRCm38)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,582,296 (GRCm38)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,755,372 (GRCm38)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,623,244 (GRCm38)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,701,972 (GRCm38)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,675,540 (GRCm38)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,609,825 (GRCm38)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,743,788 (GRCm38)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,755,291 (GRCm38)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,737,506 (GRCm38)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,577,539 (GRCm38)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,656,567 (GRCm38)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,658,562 (GRCm38)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,609,778 (GRCm38)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,690,600 (GRCm38)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,609,666 (GRCm38)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,694,849 (GRCm38)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,758,474 (GRCm38)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,808,697 (GRCm38)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,573,554 (GRCm38)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,694,878 (GRCm38)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,674,347 (GRCm38)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,649,607 (GRCm38)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,737,524 (GRCm38)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,993,023 (GRCm38)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,630,327 (GRCm38)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,598,897 (GRCm38)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,577,296 (GRCm38)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,657,222 (GRCm38)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,563,817 (GRCm38)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,704,173 (GRCm38)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,802,895 (GRCm38)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,632,437 (GRCm38)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,663,909 (GRCm38)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,770,330 (GRCm38)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,755,294 (GRCm38)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,755,293 (GRCm38)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,631,227 (GRCm38)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,618,936 (GRCm38)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,732,846 (GRCm38)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,722,424 (GRCm38)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,565,425 (GRCm38)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,646,784 (GRCm38)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,615,438 (GRCm38)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,630,728 (GRCm38)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,738,681 (GRCm38)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,697,419 (GRCm38)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,697,476 (GRCm38)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,744,960 (GRCm38)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,703,216 (GRCm38)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,992,919 (GRCm38)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,664,784 (GRCm38)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,677,302 (GRCm38)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,583,278 (GRCm38)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,697,566 (GRCm38)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,615,438 (GRCm38)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,595,118 (GRCm38)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,723,257 (GRCm38)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,743,796 (GRCm38)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,758,306 (GRCm38)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,745,033 (GRCm38)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,704,175 (GRCm38)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,734,518 (GRCm38)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,770,293 (GRCm38)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,993,051 (GRCm38)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,599,653 (GRCm38)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,773,890 (GRCm38)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,604,102 (GRCm38)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,860,367 (GRCm38)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,604,246 (GRCm38)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,700,541 (GRCm38)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,577,210 (GRCm38)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,663,873 (GRCm38)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,686,854 (GRCm38)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,748,993 (GRCm38)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,753,699 (GRCm38)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,649,580 (GRCm38)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,638,876 (GRCm38)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,722,643 (GRCm38)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,715,823 (GRCm38)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,582,337 (GRCm38)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,683,715 (GRCm38)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,733,129 (GRCm38)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,732,946 (GRCm38)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,603,814 (GRCm38)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,638,866 (GRCm38)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,683,745 (GRCm38)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,667,889 (GRCm38)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,806,445 (GRCm38)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,618,846 (GRCm38)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,563,631 (GRCm38)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,646,670 (GRCm38)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,674,430 (GRCm38)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,720,759 (GRCm38)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,630,266 (GRCm38)	nonsense	probably null
R7454:Hmcn1	UTSW	1	150,563,604 (GRCm38)	missense	probably damaging	1.00
R7476:Hmcn1	UTSW	1	150,580,267 (GRCm38)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,677,234 (GRCm38)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,622,967 (GRCm38)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,656,573 (GRCm38)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,686,780 (GRCm38)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,604,874 (GRCm38)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,655,835 (GRCm38)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,657,134 (GRCm38)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,565,329 (GRCm38)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,646,709 (GRCm38)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,667,880 (GRCm38)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,722,445 (GRCm38)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,756,592 (GRCm38)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,770,279 (GRCm38)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,806,421 (GRCm38)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,744,971 (GRCm38)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,657,470 (GRCm38)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,593,189 (GRCm38)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,664,892 (GRCm38)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,609,775 (GRCm38)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,650,084 (GRCm38)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,655,855 (GRCm38)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,664,878 (GRCm38)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,598,311 (GRCm38)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,649,992 (GRCm38)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,656,505 (GRCm38)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,749,090 (GRCm38)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,859,206 (GRCm38)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,753,660 (GRCm38)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,604,954 (GRCm38)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,646,658 (GRCm38)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,722,514 (GRCm38)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,577,477 (GRCm38)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,594,010 (GRCm38)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,819,366 (GRCm38)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,859,254 (GRCm38)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,738,764 (GRCm38)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,738,734 (GRCm38)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,758,391 (GRCm38)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,694,920 (GRCm38)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,603,800 (GRCm38)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,580,239 (GRCm38)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,573,551 (GRCm38)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,676,038 (GRCm38)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,755,257 (GRCm38)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,633,620 (GRCm38)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,680,662 (GRCm38)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,664,885 (GRCm38)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,715,718 (GRCm38)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,734,497 (GRCm38)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,655,819 (GRCm38)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,671,975 (GRCm38)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,638,908 (GRCm38)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,649,972 (GRCm38)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,773,779 (GRCm38)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,755,044 (GRCm38)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,817,119 (GRCm38)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,689,569 (GRCm38)	missense	probably benign	0.04
R9090:Hmcn1	UTSW	1	150,756,558 (GRCm38)	missense	probably damaging	1.00
R9096:Hmcn1	UTSW	1	150,657,118 (GRCm38)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,697,580 (GRCm38)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,598,390 (GRCm38)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,646,592 (GRCm38)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,630,341 (GRCm38)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,612,654 (GRCm38)	missense	probably damaging	1.00
R9204:Hmcn1	UTSW	1	150,734,511 (GRCm38)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,719,093 (GRCm38)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,597,989 (GRCm38)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,756,558 (GRCm38)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,630,295 (GRCm38)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,646,592 (GRCm38)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,669,436 (GRCm38)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,630,302 (GRCm38)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,723,497 (GRCm38)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,630,720 (GRCm38)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,586,376 (GRCm38)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,734,530 (GRCm38)	missense	probably benign	0.06
R9496:Hmcn1	UTSW	1	150,704,220 (GRCm38)	missense	probably benign	0.00
R9501:Hmcn1	UTSW	1	150,595,239 (GRCm38)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,586,376 (GRCm38)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,669,424 (GRCm38)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,622,909 (GRCm38)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,599,552 (GRCm38)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,679,595 (GRCm38)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,808,722 (GRCm38)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,630,303 (GRCm38)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,743,741 (GRCm38)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,737,605 (GRCm38)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,609,627 (GRCm38)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,798,815 (GRCm38)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,748,190 (GRCm38)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,756,588 (GRCm38)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,992,874 (GRCm38)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,722,629 (GRCm38)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,652,582 (GRCm38)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,732,938 (GRCm38)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,732,938 (GRCm38)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,732,938 (GRCm38)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,808,640 (GRCm38)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,624,561 (GRCm38)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,635,146 (GRCm38)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,700,530 (GRCm38)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,860,376 (GRCm38)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,663,901 (GRCm38)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,648,937 (GRCm38)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,663,917 (GRCm38)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,655,921 (GRCm38)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,586,445 (GRCm38)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- CTTGAAGTTTTGCGCATAGTACC -3'
(R):5'- GAGATACACCCTCTAGTAAAACTTCTG -3'

Sequencing Primer
(F):5'- CTGGAGAGCAAACCCCAGTTTTTG -3'
(R):5'- CCCTCTAGTAAAACTTCTGTGGGAG -3'

Posted On

2022-02-07