Incidental Mutation 'R9187:Mical2'
| ID |
697443 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.242)
|
| Stock # |
R9187 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 111902797 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 89
(C89*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047639
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000037991
AA Change: C89*
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: C89*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000050149
AA Change: C89*
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
AA Change: C89*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
97% (70/72) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca5 |
A |
G |
11: 110,200,961 (GRCm39) |
|
probably null |
Het |
| Abcb1a |
T |
A |
5: 8,765,016 (GRCm39) |
C669S |
probably benign |
Het |
| Abcc3 |
A |
G |
11: 94,255,913 (GRCm39) |
L524P |
probably damaging |
Het |
| Akap5 |
A |
T |
12: 76,376,745 (GRCm39) |
K726* |
probably null |
Het |
| Aldh16a1 |
T |
C |
7: 44,791,441 (GRCm39) |
E778G |
probably damaging |
Het |
| Ankle2 |
G |
A |
5: 110,400,610 (GRCm39) |
V649M |
possibly damaging |
Het |
| Apon |
A |
G |
10: 128,090,832 (GRCm39) |
N170S |
probably benign |
Het |
| Baiap2l1 |
T |
C |
5: 144,217,764 (GRCm39) |
Y274C |
probably benign |
Het |
| Bub1 |
A |
T |
2: 127,656,856 (GRCm39) |
N425K |
possibly damaging |
Het |
| Camsap1 |
A |
G |
2: 25,820,028 (GRCm39) |
C1487R |
probably damaging |
Het |
| Cd4 |
A |
C |
6: 124,844,651 (GRCm39) |
V378G |
probably damaging |
Het |
| Cenpa |
C |
A |
5: 30,824,380 (GRCm39) |
P3Q |
unknown |
Het |
| Cfap44 |
T |
C |
16: 44,225,144 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
T |
A |
1: 74,956,517 (GRCm39) |
M1021L |
probably benign |
Het |
| Ddx39a |
G |
T |
8: 84,449,113 (GRCm39) |
M300I |
probably benign |
Het |
| Dgkh |
T |
C |
14: 78,832,601 (GRCm39) |
R819G |
probably damaging |
Het |
| Dlc1 |
A |
T |
8: 37,405,786 (GRCm39) |
M1K |
probably null |
Het |
| Dnah9 |
A |
G |
11: 65,895,972 (GRCm39) |
W2468R |
probably benign |
Het |
| Ebag9 |
A |
T |
15: 44,503,706 (GRCm39) |
K177I |
probably damaging |
Het |
| Ehbp1 |
T |
C |
11: 22,101,184 (GRCm39) |
I249V |
probably damaging |
Het |
| Fam171b |
T |
C |
2: 83,710,365 (GRCm39) |
V679A |
probably damaging |
Het |
| Gabbr2 |
G |
A |
4: 46,674,533 (GRCm39) |
T818I |
probably damaging |
Het |
| Gcn1 |
T |
C |
5: 115,752,177 (GRCm39) |
S2098P |
probably damaging |
Het |
| Glb1 |
T |
C |
9: 114,302,991 (GRCm39) |
I609T |
probably damaging |
Het |
| Gm5916 |
T |
G |
9: 36,032,020 (GRCm39) |
H88P |
probably benign |
Het |
| Gon4l |
T |
C |
3: 88,786,618 (GRCm39) |
S586P |
probably benign |
Het |
| Gzmg |
T |
A |
14: 56,394,714 (GRCm39) |
T185S |
probably benign |
Het |
| Hipk3 |
T |
A |
2: 104,276,936 (GRCm39) |
D381V |
probably damaging |
Het |
| Hnrnpul2 |
C |
A |
19: 8,808,319 (GRCm39) |
N681K |
probably benign |
Het |
| Hpdl |
C |
A |
4: 116,678,372 (GRCm39) |
G30C |
probably damaging |
Het |
| Iws1 |
G |
A |
18: 32,213,213 (GRCm39) |
E214K |
possibly damaging |
Het |
| Krt82 |
C |
A |
15: 101,450,260 (GRCm39) |
V479L |
probably benign |
Het |
| Lama4 |
G |
A |
10: 38,924,124 (GRCm39) |
|
probably null |
Het |
| Lamc1 |
C |
A |
1: 153,097,434 (GRCm39) |
E1537* |
probably null |
Het |
| Mab21l3 |
G |
A |
3: 101,730,594 (GRCm39) |
T215M |
probably benign |
Het |
| Magi3 |
C |
A |
3: 103,923,073 (GRCm39) |
V1215F |
possibly damaging |
Het |
| Mitf |
T |
A |
6: 97,994,835 (GRCm39) |
V427D |
probably benign |
Het |
| Muc4 |
T |
C |
16: 32,589,102 (GRCm39) |
V753A |
|
Het |
| Myo16 |
G |
A |
8: 10,492,233 (GRCm39) |
R725H |
unknown |
Het |
| Ncapg2 |
T |
A |
12: 116,402,287 (GRCm39) |
D706E |
probably damaging |
Het |
| Ndst1 |
T |
C |
18: 60,824,268 (GRCm39) |
D803G |
probably benign |
Het |
| Neb |
A |
T |
2: 52,096,115 (GRCm39) |
V5065D |
probably damaging |
Het |
| Npm3 |
G |
A |
19: 45,737,941 (GRCm39) |
R19* |
probably null |
Het |
| Ntrk3 |
A |
C |
7: 77,896,966 (GRCm39) |
N690K |
possibly damaging |
Het |
| Or7g32 |
T |
C |
9: 19,389,166 (GRCm39) |
I127V |
probably benign |
Het |
| Or7g35 |
T |
C |
9: 19,495,950 (GRCm39) |
I39T |
probably benign |
Het |
| Or8d4 |
C |
A |
9: 40,038,886 (GRCm39) |
V124L |
possibly damaging |
Het |
| P3h2 |
G |
A |
16: 25,924,186 (GRCm39) |
A83V |
probably benign |
Het |
| Pdia2 |
A |
G |
17: 26,415,910 (GRCm39) |
S362P |
probably damaging |
Het |
| Pmp22 |
C |
T |
11: 63,025,268 (GRCm39) |
H34Y |
probably benign |
Het |
| Pmp22 |
T |
C |
11: 63,025,317 (GRCm39) |
V50A |
probably benign |
Het |
| Ppfia4 |
T |
C |
1: 134,255,006 (GRCm39) |
D283G |
probably damaging |
Het |
| Pramel58 |
T |
C |
5: 94,831,755 (GRCm39) |
V254A |
probably benign |
Het |
| Prss55 |
T |
A |
14: 64,314,531 (GRCm39) |
Q213L |
probably null |
Het |
| Rgsl1 |
C |
T |
1: 153,669,613 (GRCm39) |
E258K |
possibly damaging |
Het |
| Ripor2 |
T |
C |
13: 24,897,632 (GRCm39) |
F777L |
probably benign |
Het |
| Rsf1 |
GGC |
GGCGGCGGCCGC |
7: 97,229,140 (GRCm39) |
|
probably benign |
Het |
| Sgce |
G |
A |
6: 4,711,362 (GRCm39) |
R173C |
probably benign |
Het |
| Sncaip |
T |
G |
18: 53,040,011 (GRCm39) |
M735R |
probably benign |
Het |
| Snrpd2 |
T |
A |
7: 18,886,505 (GRCm39) |
I96N |
probably damaging |
Het |
| Spryd3 |
T |
G |
15: 102,039,110 (GRCm39) |
D121A |
probably damaging |
Het |
| Srsf3-ps |
A |
G |
11: 98,516,187 (GRCm39) |
V62A |
possibly damaging |
Het |
| Sspo |
T |
C |
6: 48,472,223 (GRCm39) |
C149R |
probably damaging |
Het |
| Tbc1d10b |
A |
T |
7: 126,807,105 (GRCm39) |
M144K |
probably benign |
Het |
| Tbc1d31 |
T |
A |
15: 57,779,485 (GRCm39) |
I66N |
probably damaging |
Het |
| Tssk1 |
A |
G |
16: 17,712,457 (GRCm39) |
T81A |
possibly damaging |
Het |
| Ttc28 |
A |
G |
5: 111,249,902 (GRCm39) |
Y284C |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,573,755 (GRCm39) |
T25713A |
probably benign |
Het |
| Vmn2r125 |
T |
C |
4: 156,703,554 (GRCm39) |
W311R |
probably damaging |
Het |
| Vmn2r80 |
A |
T |
10: 79,030,438 (GRCm39) |
T755S |
probably benign |
Het |
| Vmn2r98 |
T |
C |
17: 19,301,481 (GRCm39) |
C828R |
probably damaging |
Het |
| Wwox |
T |
C |
8: 115,438,978 (GRCm39) |
F348S |
probably damaging |
Het |
| Zeb2 |
T |
A |
2: 45,000,040 (GRCm39) |
R65W |
possibly damaging |
Het |
| Zfp712 |
T |
A |
13: 67,188,637 (GRCm39) |
H630L |
probably damaging |
Het |
| Zfp764 |
G |
T |
7: 127,004,608 (GRCm39) |
H174Q |
probably damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTTAGAACCACCTGTGCATC -3'
(R):5'- CCCATAGAACTTCTTGGCCC -3'
Sequencing Primer
(F):5'- TAGAACCACCTGTGCATCTTACAGTG -3'
(R):5'- ATAGAACTTCTTGGCCCCCAGG -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation