Incidental Mutation 'R9189:Greb1l'
| ID |
697647 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Greb1l
|
| Ensembl Gene |
ENSMUSG00000042942 |
| Gene Name |
growth regulation by estrogen in breast cancer-like |
| Synonyms |
AK220484, mKIAA4095 |
| MMRRC Submission |
068951-MU
|
| Accession Numbers |
Genbank: NM_001083628; MGI: 3576497 |
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9189 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
10325177-10562934 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 10499983 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 350
(V350A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049003
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048977]
[ENSMUST00000172532]
|
| AlphaFold |
B9EJV3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000048977
AA Change: V350A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049003
Gene: ENSMUSG00000042942
AA Change: V350A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:GREB1
|
1 |
1172 |
N/A |
PFAM |
|
Pfam:GREB1
|
1154 |
1913 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172532
AA Change: V350A
PolyPhen 2
Score 0.060 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000134090
Gene: ENSMUSG00000042942
AA Change: V350A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
83 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
301 |
N/A |
INTRINSIC |
|
low complexity region
|
606 |
617 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(5) : Targeted, other(2) Gene trapped(3) |
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acox1 |
T |
A |
11: 116,174,405 (GRCm38) |
D608V |
probably damaging |
Het |
| Actg1 |
A |
T |
11: 120,348,187 (GRCm38) |
C26S |
unknown |
Het |
| Ahnak |
T |
A |
19: 9,010,883 (GRCm38) |
V3177E |
possibly damaging |
Het |
| Akap11 |
G |
A |
14: 78,513,498 (GRCm38) |
T483I |
|
Het |
| Akr1cl |
A |
G |
1: 65,024,671 (GRCm38) |
S120P |
probably benign |
Het |
| Ankle2 |
G |
A |
5: 110,252,744 (GRCm38) |
V649M |
possibly damaging |
Het |
| Ankrd55 |
A |
T |
13: 112,368,036 (GRCm38) |
I439F |
probably damaging |
Het |
| Asb8 |
A |
G |
15: 98,142,754 (GRCm38) |
M9T |
possibly damaging |
Het |
| Ascc1 |
A |
T |
10: 60,007,823 (GRCm38) |
Y69F |
probably benign |
Het |
| Atp9a |
A |
T |
2: 168,676,140 (GRCm38) |
|
probably null |
Het |
| Cd8b1 |
T |
C |
6: 71,329,768 (GRCm38) |
F160L |
probably benign |
Het |
| Cdh23 |
G |
A |
10: 60,307,527 (GRCm38) |
A3005V |
possibly damaging |
Het |
| Cep250 |
A |
G |
2: 155,976,430 (GRCm38) |
T842A |
probably benign |
Het |
| Cgnl1 |
T |
A |
9: 71,723,565 (GRCm38) |
K552* |
probably null |
Het |
| Cntnap4 |
C |
T |
8: 112,875,968 (GRCm38) |
T1227M |
possibly damaging |
Het |
| Cobll1 |
C |
A |
2: 65,150,989 (GRCm38) |
V86F |
probably damaging |
Het |
| Dchs2 |
A |
G |
3: 83,348,254 (GRCm38) |
N2419S |
probably damaging |
Het |
| Dhx30 |
A |
T |
9: 110,085,426 (GRCm38) |
L1001* |
probably null |
Het |
| Diaph1 |
C |
T |
18: 37,891,109 (GRCm38) |
V559M |
unknown |
Het |
| Dis3l |
A |
T |
9: 64,310,449 (GRCm38) |
H783Q |
probably benign |
Het |
| Dock7 |
T |
G |
4: 98,989,113 (GRCm38) |
T1063P |
unknown |
Het |
| Dsc1 |
T |
C |
18: 20,099,157 (GRCm38) |
T265A |
possibly damaging |
Het |
| Eif2ak4 |
A |
T |
2: 118,427,912 (GRCm38) |
Q581L |
probably damaging |
Het |
| Eprs |
A |
T |
1: 185,374,137 (GRCm38) |
D183V |
possibly damaging |
Het |
| Fads2 |
G |
C |
19: 10,091,819 (GRCm38) |
D80E |
probably benign |
Het |
| Fam167b |
G |
A |
4: 129,577,082 (GRCm38) |
R158C |
probably damaging |
Het |
| Fam71a |
G |
A |
1: 191,162,703 (GRCm38) |
T581I |
possibly damaging |
Het |
| Flnb |
T |
A |
14: 7,892,976 (GRCm38) |
I682K |
possibly damaging |
Het |
| Gpatch2l |
C |
T |
12: 86,244,378 (GRCm38) |
P112S |
probably benign |
Het |
| Gpn1 |
T |
A |
5: 31,497,366 (GRCm38) |
H87Q |
unknown |
Het |
| Grm5 |
A |
T |
7: 88,074,816 (GRCm38) |
K771N |
probably damaging |
Het |
| Gucy2c |
C |
T |
6: 136,751,047 (GRCm38) |
S319N |
probably benign |
Het |
| Hcfc2 |
G |
T |
10: 82,699,207 (GRCm38) |
A22S |
probably benign |
Het |
| Hist1h2bg |
A |
G |
13: 23,571,587 (GRCm38) |
D52G |
probably damaging |
Het |
| Hnf4a |
A |
G |
2: 163,551,577 (GRCm38) |
D39G |
probably benign |
Het |
| Il6st |
C |
T |
13: 112,498,806 (GRCm38) |
T584M |
probably damaging |
Het |
| Irf3 |
T |
A |
7: 45,000,822 (GRCm38) |
V254E |
possibly damaging |
Het |
| Iws1 |
G |
A |
18: 32,080,160 (GRCm38) |
E214K |
possibly damaging |
Het |
| Kank4 |
T |
A |
4: 98,780,052 (GRCm38) |
K53* |
probably null |
Het |
| Kcnj11 |
A |
T |
7: 46,098,752 (GRCm38) |
F382L |
possibly damaging |
Het |
| Kcnq3 |
T |
C |
15: 65,995,661 (GRCm38) |
Y711C |
probably damaging |
Het |
| Kctd3 |
A |
G |
1: 188,972,439 (GRCm38) |
S712P |
possibly damaging |
Het |
| Krt20 |
A |
G |
11: 99,432,261 (GRCm38) |
I245T |
possibly damaging |
Het |
| Larp1b |
T |
C |
3: 40,970,604 (GRCm38) |
I219T |
probably damaging |
Het |
| Lman2l |
A |
G |
1: 36,439,690 (GRCm38) |
F114L |
probably damaging |
Het |
| Loxl2 |
T |
A |
14: 69,692,410 (GRCm38) |
Y746N |
possibly damaging |
Het |
| Lrrc43 |
T |
C |
5: 123,508,046 (GRCm38) |
S628P |
probably benign |
Het |
| Mroh8 |
A |
C |
2: 157,269,625 (GRCm38) |
D136E |
probably damaging |
Het |
| Nek8 |
T |
A |
11: 78,172,516 (GRCm38) |
M141L |
probably benign |
Het |
| Nr2e1 |
C |
A |
10: 42,578,272 (GRCm38) |
R22L |
probably damaging |
Het |
| Nr6a1 |
C |
T |
2: 38,926,117 (GRCm38) |
|
probably null |
Het |
| Olfr1164 |
A |
G |
2: 88,093,850 (GRCm38) |
F29L |
probably damaging |
Het |
| Olfr1167 |
T |
C |
2: 88,149,564 (GRCm38) |
M152V |
probably benign |
Het |
| Olfr1377 |
T |
A |
11: 50,985,339 (GRCm38) |
C213S |
probably damaging |
Het |
| Olfr3 |
T |
A |
2: 36,812,202 (GRCm38) |
M297L |
possibly damaging |
Het |
| Onecut2 |
A |
G |
18: 64,340,819 (GRCm38) |
Y147C |
probably damaging |
Het |
| Pcdhac2 |
T |
C |
18: 37,144,263 (GRCm38) |
F99L |
probably benign |
Het |
| Pcdhga2 |
T |
G |
18: 37,669,742 (GRCm38) |
V213G |
possibly damaging |
Het |
| Pgap1 |
A |
T |
1: 54,480,749 (GRCm38) |
V909E |
probably benign |
Het |
| Pik3r4 |
A |
T |
9: 105,669,839 (GRCm38) |
T939S |
probably benign |
Het |
| Pip4k2c |
T |
C |
10: 127,199,377 (GRCm38) |
D374G |
possibly damaging |
Het |
| Plxdc1 |
A |
T |
11: 97,953,962 (GRCm38) |
D252E |
probably benign |
Het |
| Pm20d1 |
A |
C |
1: 131,802,377 (GRCm38) |
D218A |
probably damaging |
Het |
| Polq |
C |
A |
16: 37,044,903 (GRCm38) |
Q706K |
probably damaging |
Het |
| Pram1 |
A |
T |
17: 33,641,157 (GRCm38) |
I233F |
probably benign |
Het |
| Prr27 |
C |
A |
5: 87,843,135 (GRCm38) |
P202Q |
probably benign |
Het |
| Prss41 |
A |
T |
17: 23,842,387 (GRCm38) |
H143Q |
probably damaging |
Het |
| Ptpn21 |
A |
G |
12: 98,689,002 (GRCm38) |
Y569H |
probably damaging |
Het |
| Rad17 |
T |
C |
13: 100,637,056 (GRCm38) |
K142E |
probably damaging |
Het |
| Rcan3 |
T |
C |
4: 135,425,296 (GRCm38) |
E38G |
probably benign |
Het |
| Rgl3 |
C |
A |
9: 21,974,060 (GRCm38) |
R658L |
possibly damaging |
Het |
| Rnf125 |
T |
A |
18: 20,983,183 (GRCm38) |
*141K |
probably null |
Het |
| Ros1 |
G |
T |
10: 52,143,406 (GRCm38) |
N711K |
probably damaging |
Het |
| Rsph10b |
T |
A |
5: 143,959,686 (GRCm38) |
Y421N |
probably benign |
Het |
| Ryr1 |
C |
T |
7: 29,077,046 (GRCm38) |
V2222I |
probably damaging |
Het |
| Samsn1 |
C |
T |
16: 75,859,561 (GRCm38) |
C333Y |
probably damaging |
Het |
| Slc9a2 |
G |
A |
1: 40,755,784 (GRCm38) |
E502K |
probably benign |
Het |
| Stard9 |
A |
T |
2: 120,703,019 (GRCm38) |
E3252D |
possibly damaging |
Het |
| Syne1 |
T |
C |
10: 5,222,289 (GRCm38) |
I5051V |
probably benign |
Het |
| Syne1 |
C |
A |
10: 5,173,008 (GRCm38) |
R309S |
probably damaging |
Het |
| Syngap1 |
A |
G |
17: 26,964,974 (GRCm38) |
S1241G |
probably damaging |
Het |
| Tbpl2 |
T |
C |
2: 24,076,018 (GRCm38) |
K321R |
probably damaging |
Het |
| Tnrc18 |
C |
T |
5: 142,731,352 (GRCm38) |
G2449E |
probably damaging |
Het |
| Trim25 |
A |
G |
11: 89,010,905 (GRCm38) |
D342G |
probably benign |
Het |
| Tssk4 |
T |
A |
14: 55,650,447 (GRCm38) |
H33Q |
probably benign |
Het |
| Ttc3 |
G |
A |
16: 94,467,972 (GRCm38) |
G1971D |
possibly damaging |
Het |
| Tufm |
C |
T |
7: 126,489,677 (GRCm38) |
Q347* |
probably null |
Het |
| Ubxn10 |
G |
A |
4: 138,720,822 (GRCm38) |
S181F |
possibly damaging |
Het |
| Ushbp1 |
T |
C |
8: 71,388,895 (GRCm38) |
E430G |
probably benign |
Het |
| Vmn1r33 |
T |
C |
6: 66,611,732 (GRCm38) |
I279M |
possibly damaging |
Het |
| Vmn2r115 |
T |
C |
17: 23,345,810 (GRCm38) |
F224L |
probably damaging |
Het |
| Vmn2r23 |
A |
T |
6: 123,704,364 (GRCm38) |
H77L |
probably benign |
Het |
| Vps13a |
T |
C |
19: 16,686,597 (GRCm38) |
I1481V |
probably benign |
Het |
| Vps35 |
T |
C |
8: 85,281,269 (GRCm38) |
N294S |
possibly damaging |
Het |
| Washc3 |
A |
T |
10: 88,216,054 (GRCm38) |
T102S |
probably benign |
Het |
| Zfp27 |
T |
A |
7: 29,895,934 (GRCm38) |
E202V |
possibly damaging |
Het |
| Zfp58 |
T |
C |
13: 67,491,916 (GRCm38) |
H152R |
possibly damaging |
Het |
| Zfr2 |
T |
C |
10: 81,244,662 (GRCm38) |
V390A |
probably damaging |
Het |
|
| Other mutations in Greb1l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00485:Greb1l
|
APN |
18 |
10,555,962 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL01554:Greb1l
|
APN |
18 |
10,522,144 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01563:Greb1l
|
APN |
18 |
10,469,399 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01944:Greb1l
|
APN |
18 |
10,557,280 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL02110:Greb1l
|
APN |
18 |
10,515,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02249:Greb1l
|
APN |
18 |
10,532,961 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02318:Greb1l
|
APN |
18 |
10,469,388 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL02340:Greb1l
|
APN |
18 |
10,515,200 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02516:Greb1l
|
APN |
18 |
10,537,064 (GRCm38) |
missense |
probably benign |
0.31 |
|
IGL02566:Greb1l
|
APN |
18 |
10,503,299 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02583:Greb1l
|
APN |
18 |
10,542,362 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02838:Greb1l
|
APN |
18 |
10,560,430 (GRCm38) |
missense |
probably damaging |
1.00 |
|
A4554:Greb1l
|
UTSW |
18 |
10,532,862 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
PIT4453001:Greb1l
|
UTSW |
18 |
10,533,032 (GRCm38) |
missense |
probably benign |
0.08 |
|
PIT4453001:Greb1l
|
UTSW |
18 |
10,533,031 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0099:Greb1l
|
UTSW |
18 |
10,509,158 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0226:Greb1l
|
UTSW |
18 |
10,522,076 (GRCm38) |
intron |
probably benign |
|
|
R0234:Greb1l
|
UTSW |
18 |
10,560,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0234:Greb1l
|
UTSW |
18 |
10,560,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0239:Greb1l
|
UTSW |
18 |
10,458,567 (GRCm38) |
splice site |
probably benign |
|
|
R0316:Greb1l
|
UTSW |
18 |
10,547,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0369:Greb1l
|
UTSW |
18 |
10,469,375 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R0394:Greb1l
|
UTSW |
18 |
10,523,374 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0478:Greb1l
|
UTSW |
18 |
10,509,281 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0555:Greb1l
|
UTSW |
18 |
10,458,781 (GRCm38) |
splice site |
probably benign |
|
|
R0671:Greb1l
|
UTSW |
18 |
10,474,303 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1282:Greb1l
|
UTSW |
18 |
10,547,289 (GRCm38) |
missense |
probably benign |
0.13 |
|
R1574:Greb1l
|
UTSW |
18 |
10,554,997 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1574:Greb1l
|
UTSW |
18 |
10,554,997 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1607:Greb1l
|
UTSW |
18 |
10,529,703 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1666:Greb1l
|
UTSW |
18 |
10,529,708 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1666:Greb1l
|
UTSW |
18 |
10,501,080 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1720:Greb1l
|
UTSW |
18 |
10,553,848 (GRCm38) |
missense |
probably benign |
0.19 |
|
R1808:Greb1l
|
UTSW |
18 |
10,542,143 (GRCm38) |
missense |
probably benign |
|
|
R1829:Greb1l
|
UTSW |
18 |
10,509,314 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1897:Greb1l
|
UTSW |
18 |
10,498,992 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1967:Greb1l
|
UTSW |
18 |
10,501,049 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2025:Greb1l
|
UTSW |
18 |
10,515,221 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R2086:Greb1l
|
UTSW |
18 |
10,523,281 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2125:Greb1l
|
UTSW |
18 |
10,511,422 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2139:Greb1l
|
UTSW |
18 |
10,555,011 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2255:Greb1l
|
UTSW |
18 |
10,554,857 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2256:Greb1l
|
UTSW |
18 |
10,503,307 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2257:Greb1l
|
UTSW |
18 |
10,503,307 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2880:Greb1l
|
UTSW |
18 |
10,547,288 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R3623:Greb1l
|
UTSW |
18 |
10,542,380 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3778:Greb1l
|
UTSW |
18 |
10,469,444 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R3975:Greb1l
|
UTSW |
18 |
10,522,247 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R4038:Greb1l
|
UTSW |
18 |
10,515,209 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4062:Greb1l
|
UTSW |
18 |
10,522,150 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4134:Greb1l
|
UTSW |
18 |
10,529,708 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4342:Greb1l
|
UTSW |
18 |
10,544,561 (GRCm38) |
missense |
probably benign |
0.12 |
|
R4409:Greb1l
|
UTSW |
18 |
10,503,182 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R4600:Greb1l
|
UTSW |
18 |
10,553,705 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4618:Greb1l
|
UTSW |
18 |
10,498,965 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4683:Greb1l
|
UTSW |
18 |
10,529,563 (GRCm38) |
splice site |
probably null |
|
|
R4686:Greb1l
|
UTSW |
18 |
10,522,112 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4707:Greb1l
|
UTSW |
18 |
10,532,922 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4780:Greb1l
|
UTSW |
18 |
10,541,792 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4819:Greb1l
|
UTSW |
18 |
10,458,358 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4925:Greb1l
|
UTSW |
18 |
10,547,447 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R4960:Greb1l
|
UTSW |
18 |
10,547,306 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5150:Greb1l
|
UTSW |
18 |
10,555,950 (GRCm38) |
frame shift |
probably null |
|
|
R5154:Greb1l
|
UTSW |
18 |
10,458,312 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5269:Greb1l
|
UTSW |
18 |
10,511,409 (GRCm38) |
missense |
probably benign |
|
|
R5290:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5310:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5328:Greb1l
|
UTSW |
18 |
10,553,720 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5337:Greb1l
|
UTSW |
18 |
10,509,143 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5393:Greb1l
|
UTSW |
18 |
10,458,312 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5402:Greb1l
|
UTSW |
18 |
10,537,169 (GRCm38) |
missense |
probably benign |
0.26 |
|
R5718:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5719:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5720:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5721:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5902:Greb1l
|
UTSW |
18 |
10,538,302 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5993:Greb1l
|
UTSW |
18 |
10,544,455 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6035:Greb1l
|
UTSW |
18 |
10,501,025 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R6035:Greb1l
|
UTSW |
18 |
10,501,025 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R6045:Greb1l
|
UTSW |
18 |
10,547,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6063:Greb1l
|
UTSW |
18 |
10,557,340 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6297:Greb1l
|
UTSW |
18 |
10,469,494 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6405:Greb1l
|
UTSW |
18 |
10,501,076 (GRCm38) |
missense |
probably benign |
0.30 |
|
R6552:Greb1l
|
UTSW |
18 |
10,541,814 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6572:Greb1l
|
UTSW |
18 |
10,522,131 (GRCm38) |
missense |
probably benign |
0.07 |
|
R6575:Greb1l
|
UTSW |
18 |
10,547,347 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6922:Greb1l
|
UTSW |
18 |
10,547,482 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6957:Greb1l
|
UTSW |
18 |
10,558,786 (GRCm38) |
missense |
probably benign |
0.23 |
|
R6962:Greb1l
|
UTSW |
18 |
10,547,327 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7012:Greb1l
|
UTSW |
18 |
10,529,707 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7179:Greb1l
|
UTSW |
18 |
10,544,576 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7251:Greb1l
|
UTSW |
18 |
10,515,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7275:Greb1l
|
UTSW |
18 |
10,544,561 (GRCm38) |
missense |
probably benign |
0.12 |
|
R7301:Greb1l
|
UTSW |
18 |
10,544,970 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7307:Greb1l
|
UTSW |
18 |
10,538,142 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7455:Greb1l
|
UTSW |
18 |
10,554,915 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7832:Greb1l
|
UTSW |
18 |
10,542,056 (GRCm38) |
missense |
probably benign |
0.38 |
|
R7934:Greb1l
|
UTSW |
18 |
10,474,371 (GRCm38) |
nonsense |
probably null |
|
|
R8137:Greb1l
|
UTSW |
18 |
10,474,357 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R8138:Greb1l
|
UTSW |
18 |
10,533,060 (GRCm38) |
missense |
probably benign |
0.13 |
|
R8208:Greb1l
|
UTSW |
18 |
10,510,703 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8227:Greb1l
|
UTSW |
18 |
10,515,371 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8312:Greb1l
|
UTSW |
18 |
10,511,587 (GRCm38) |
intron |
probably benign |
|
|
R8331:Greb1l
|
UTSW |
18 |
10,458,706 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R8364:Greb1l
|
UTSW |
18 |
10,529,687 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R8389:Greb1l
|
UTSW |
18 |
10,529,613 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8695:Greb1l
|
UTSW |
18 |
10,544,450 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8795:Greb1l
|
UTSW |
18 |
10,553,739 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8836:Greb1l
|
UTSW |
18 |
10,509,257 (GRCm38) |
missense |
probably benign |
0.30 |
|
R8862:Greb1l
|
UTSW |
18 |
10,555,042 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R8872:Greb1l
|
UTSW |
18 |
10,529,684 (GRCm38) |
missense |
probably benign |
0.18 |
|
R8874:Greb1l
|
UTSW |
18 |
10,544,896 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8886:Greb1l
|
UTSW |
18 |
10,553,843 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8921:Greb1l
|
UTSW |
18 |
10,541,825 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8997:Greb1l
|
UTSW |
18 |
10,510,747 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9015:Greb1l
|
UTSW |
18 |
10,541,675 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9018:Greb1l
|
UTSW |
18 |
10,542,004 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R9074:Greb1l
|
UTSW |
18 |
10,558,795 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9074:Greb1l
|
UTSW |
18 |
10,532,797 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9117:Greb1l
|
UTSW |
18 |
10,542,422 (GRCm38) |
missense |
probably benign |
0.31 |
|
R9332:Greb1l
|
UTSW |
18 |
10,532,796 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R9367:Greb1l
|
UTSW |
18 |
10,522,130 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9497:Greb1l
|
UTSW |
18 |
10,458,600 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9796:Greb1l
|
UTSW |
18 |
10,538,233 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
Z1176:Greb1l
|
UTSW |
18 |
10,515,305 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATCACAGGCAAGGTCCTC -3'
(R):5'- ACACGGTTAAAACTAAGGTCAGTTG -3'
Sequencing Primer
(F):5'- AAGGTCCTCTGAGCACTTGG -3'
(R):5'- GGTCAGTTGTAACAGTACATGAAC -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation