Incidental Mutation 'R9194:Vmn1r36'
ID 697856
Institutional Source Beutler Lab
Gene Symbol Vmn1r36
Ensembl Gene ENSMUSG00000115482
Gene Name vomeronasal 1 receptor 36
Synonyms V1rc11
MMRRC Submission
Accession Numbers
Essential gene? Probably non essential (E-score: 0.144) question?
Stock # R9194 (G1)
Quality Score 225.009
Status Validated
Chromosome 6
Chromosomal Location 66715257-66719168 bp(-) (GRCm38)
Type of Mutation nonsense
DNA Base Change (assembly) G to A at 66716052 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Glutamine to Stop codon at position 280 (Q280*)
Ref Sequence ENSEMBL: ENSMUSP00000153849 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000226142] [ENSMUST00000226635] [ENSMUST00000226728] [ENSMUST00000226829]
AlphaFold Q8R2E3
Predicted Effect probably null
Transcript: ENSMUST00000226142
AA Change: Q243*
Predicted Effect probably null
Transcript: ENSMUST00000226635
AA Change: Q280*
Predicted Effect probably null
Transcript: ENSMUST00000226728
AA Change: Q174*
Predicted Effect probably null
Transcript: ENSMUST00000226829
AA Change: Q280*
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 100.0%
  • 10x: 99.7%
  • 20x: 99.0%
Validation Efficiency 94% (44/47)
Allele List at MGI
Other mutations in this stock
Total: 46 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700017B05Rik A T 9: 57,259,088 M1K probably null Het
Adra1b A T 11: 43,835,436 V218D probably damaging Het
Ank1 A G 8: 23,116,239 S1216G possibly damaging Het
Celsr1 G T 15: 86,033,085 S229* probably null Het
Cfap44 G T 16: 44,468,461 D1525Y probably damaging Het
Chd8 A T 14: 52,202,193 M2341K probably benign Het
Chst11 A G 10: 83,191,485 T249A probably damaging Het
Cttnbp2 A G 6: 18,434,851 V336A probably benign Het
Dennd3 T C 15: 73,547,304 L648P probably benign Het
Dgcr14 A T 16: 17,910,164 D79E probably damaging Het
Dhx16 T C 17: 35,889,281 V864A probably benign Het
Enpp3 G A 10: 24,799,194 H362Y possibly damaging Het
Fam83c T A 2: 155,829,379 Y712F probably damaging Het
Helz C T 11: 107,670,287 Q1392* probably null Het
Il18rap C T 1: 40,543,017 T366M probably benign Het
Iqch T C 9: 63,572,679 H143R probably benign Het
Itgb5 A G 16: 33,900,511 D315G probably damaging Het
Kcnmb2 A G 3: 32,182,025 K141R probably benign Het
Lrrc37a G A 11: 103,500,850 P1250S probably benign Het
Mcm5 T G 8: 75,110,334 V110G probably damaging Het
Med27 G A 2: 29,471,300 D163N probably damaging Het
Mms22l C A 4: 24,600,185 Y1129* probably null Het
Mov10l1 G A 15: 89,046,820 R1081H probably damaging Het
Mtpap C G 18: 4,380,833 N170K probably benign Het
Mtpap C T 18: 4,380,834 Q171* probably null Het
Myo6 T A 9: 80,246,554 F271I unknown Het
Ndst4 C T 3: 125,724,736 S354L probably benign Het
Nfatc1 C T 18: 80,708,043 A26T probably benign Het
Olfr867 C A 9: 20,055,247 C72F probably damaging Het
Piezo2 G C 18: 63,117,744 T428S probably benign Het
Prkch A G 12: 73,721,842 E462G probably damaging Het
Rbm20 A G 19: 53,834,700 Y576C probably damaging Het
Riok3 TTTCATT TTT 18: 12,149,585 probably null Het
Rpp40 C T 13: 35,896,915 D302N probably benign Het
Sash1 A G 10: 8,740,205 V631A probably damaging Het
Sstr2 A G 11: 113,624,377 T41A probably benign Het
Thsd7b T A 1: 129,915,634 V861E possibly damaging Het
Tomm70a A G 16: 57,152,707 K603E possibly damaging Het
Tpd52l2 T A 2: 181,499,890 M22K possibly damaging Het
Tpst1 T A 5: 130,102,019 L110Q possibly damaging Het
Tram1l1 A G 3: 124,321,488 Y99C possibly damaging Het
Ttc39b A G 4: 83,263,740 F81L possibly damaging Het
Ubr1 A G 2: 120,947,844 Y238H probably damaging Het
Vmn1r202 G T 13: 22,502,146 H34N possibly damaging Het
Xpnpep1 A T 19: 53,011,858 V187E possibly damaging Het
Zfp592 A G 7: 81,024,601 I438V probably benign Het
Other mutations in Vmn1r36
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01384:Vmn1r36 APN 6 66716462 missense probably damaging 0.98
R0610:Vmn1r36 UTSW 6 66716420 missense probably damaging 0.99
R0864:Vmn1r36 UTSW 6 66716856 missense probably null
R1754:Vmn1r36 UTSW 6 66716533 frame shift probably null
R1813:Vmn1r36 UTSW 6 66716772 missense probably benign
R1844:Vmn1r36 UTSW 6 66716763 missense probably benign 0.00
R1896:Vmn1r36 UTSW 6 66716772 missense probably benign
R2987:Vmn1r36 UTSW 6 66716716 missense probably benign 0.05
R4852:Vmn1r36 UTSW 6 66716888 start codon destroyed probably null 1.00
R4899:Vmn1r36 UTSW 6 66716565 missense possibly damaging 0.93
R5985:Vmn1r36 UTSW 6 66716871 missense probably benign 0.02
R6235:Vmn1r36 UTSW 6 66716246 missense probably benign 0.00
R7313:Vmn1r36 UTSW 6 66716123 missense probably benign
R7511:Vmn1r36 UTSW 6 66716930 start gained probably benign
R8046:Vmn1r36 UTSW 6 66715980 nonsense probably null
R8143:Vmn1r36 UTSW 6 66716052 nonsense probably null
R8870:Vmn1r36 UTSW 6 66716736 missense probably benign 0.00
R8871:Vmn1r36 UTSW 6 66716458 nonsense probably null
R9335:Vmn1r36 UTSW 6 66716446 nonsense probably null
Predicted Primers PCR Primer
(F):5'- ATGAAGAATCTTGCTTTGCTGCTTG -3'
(R):5'- CTGAGAAAAGGGCCACTCAG -3'

Sequencing Primer
(F):5'- TCCAGAGGATCTCATGAGCTC -3'
(R):5'- CAGACCATCTTGCTGCTGGTG -3'
Posted On 2022-02-07