Mutagenetix > Incidental Mutation

Incidental Mutation 'R9205:Nbeal1'

698414

Institutional Source

Beutler Lab

Gene Symbol

Nbeal1

Ensembl Gene

ENSMUSG00000073664

Gene Name

neurobeachin like 1

Synonyms

A530083I02Rik, A530050O19Rik, ALS2CR17, 2310076G13Rik

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9205 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

60219758-60377487 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 60317839 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 1925 (D1925E)

Ref Sequence

ENSEMBL: ENSMUSP00000124056 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160834] [ENSMUST00000162291]

AlphaFold

E9PYP2

Predicted Effect

SMART Domains

Protein: ENSMUSP00000049393
Gene: ENSMUSG00000073664
AA Change: D658E

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
low complexity region	719	735	N/A	INTRINSIC
Pfam:DUF4704	851	1130	3.4e-39	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
Pfam:DUF4800	1575	1828	6.3e-126	PFAM
coiled coil region	1859	1882	N/A	INTRINSIC
Pfam:PH_BEACH	1889	1975	2e-24	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000159344

SMART Domains

Protein: ENSMUSP00000124850
Gene: ENSMUSG00000073664

Domain	Start	End	E-Value	Type
Beach	31	246	4.21e-109	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000160834
AA Change: D1925E

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000124056
Gene: ENSMUSG00000073664
AA Change: D1925E

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
Pfam:Laminin_G_3	567	801	8.3e-9	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
low complexity region	1849	1865	N/A	INTRINSIC
Pfam:PH_BEACH	1882	1975	4.9e-32	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000162291
AA Change: D656E

PolyPhen 2 Score 0.507 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000125592
Gene: ENSMUSG00000073664
AA Change: D656E

Domain	Start	End	E-Value	Type
low complexity region	114	132	N/A	INTRINSIC
low complexity region	580	596	N/A	INTRINSIC
Pfam:PH_BEACH	613	706	9.6e-33	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.3%

Validation Efficiency

95% (76/80)

Allele List at MGI

All alleles(16) : Targeted(1) Gene trapped(15)

Other mutations in this stock

Total: 79 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aebp2	T	A	6: 140,587,954 (GRCm39)	H341Q	probably damaging	Het
Apob	G	A	12: 8,030,635 (GRCm39)	A125T	probably damaging	Het
Bace2	G	T	16: 97,158,059 (GRCm39)	A20S	unknown	Het
Bcar1	T	C	8: 112,442,341 (GRCm39)	Y238C	probably damaging	Het
Brinp3	A	T	1: 146,777,827 (GRCm39)	D758V	possibly damaging	Het
Btnl10	T	C	11: 58,811,345 (GRCm39)	S223P	probably damaging	Het
Cckar	C	T	5: 53,864,587 (GRCm39)		probably null	Het
Cdhr2	A	G	13: 54,861,801 (GRCm39)	N66S	probably benign	Het
Chd9	A	G	8: 91,757,270 (GRCm39)	M1890V	probably benign	Het
Col6a5	C	T	9: 105,755,837 (GRCm39)	G2196R	probably damaging	Het
Col9a1	T	G	1: 24,224,175 (GRCm39)	M119R	unknown	Het
Cryaa	A	G	17: 31,898,642 (GRCm39)	H123R	probably damaging	Het
Cux1	A	T	5: 136,398,989 (GRCm39)	D171E	probably damaging	Het
Dgkz	T	A	2: 91,764,144 (GRCm39)	T1067S	probably benign	Het
Dnah11	C	T	12: 117,991,251 (GRCm39)	E2372K	probably damaging	Het
Dnah5	T	C	15: 28,448,480 (GRCm39)	M4181T	possibly damaging	Het
Dnajb14	A	G	3: 137,614,145 (GRCm39)	E352G	possibly damaging	Het
Dnmt3l	T	A	10: 77,892,586 (GRCm39)		probably null	Het
Dph6	T	C	2: 114,399,995 (GRCm39)	I117V	probably damaging	Het
Dsg1a	A	G	18: 20,473,228 (GRCm39)	D767G	probably damaging	Het
Edn3	C	T	2: 174,603,482 (GRCm39)	P77S	possibly damaging	Het
Fbln7	A	C	2: 128,737,168 (GRCm39)	S328R	probably null	Het
Fbn2	T	C	18: 58,192,428 (GRCm39)	R1518G	probably damaging	Het
Foxi2	A	T	7: 135,013,525 (GRCm39)	T252S	probably benign	Het
Foxred2	A	G	15: 77,836,206 (GRCm39)	S384P	probably damaging	Het
Gdpd1	G	A	11: 86,936,009 (GRCm39)	H174Y	probably benign	Het
Gm10542	A	C	18: 44,337,705 (GRCm39)	D61A	possibly damaging	Het
Gm10563	TTCCTCCTCCTCCTCCTCCTCTTCCTCCTCCTCCTCCTCCTC	TTCCTCCTCCTCCTCCTCTTCCTCCTCCTCCTCCTCCTC	4: 155,720,307 (GRCm39)		probably benign	Het
H2-Ab1	A	G	17: 34,483,981 (GRCm39)	E114G	probably damaging	Het
Htt	C	T	5: 34,976,367 (GRCm39)	T723M	probably benign	Het
Igfn1	C	T	1: 135,903,695 (GRCm39)	V348I	probably damaging	Het
Itpr1	T	A	6: 108,466,810 (GRCm39)	L2173Q	probably damaging	Het
Lamp5	A	G	2: 135,901,521 (GRCm39)	Y115C	probably damaging	Het
Lrp1	T	A	10: 127,430,850 (GRCm39)	K400*	probably null	Het
Man2a2	C	T	7: 80,010,868 (GRCm39)	V708I	probably benign	Het
Matr3	T	C	18: 35,720,774 (GRCm39)	S746P	probably benign	Het
Me1	C	T	9: 86,480,847 (GRCm39)	V353M	probably benign	Het
Mideas	A	C	12: 84,199,661 (GRCm39)	F1020V	probably benign	Het
Oca2	T	A	7: 55,966,168 (GRCm39)	F387I	probably damaging	Het
Opn3	G	T	1: 175,490,655 (GRCm39)	N335K	probably benign	Het
Or5d36	T	A	2: 87,900,778 (GRCm39)	H316L	probably benign	Het
Or5k17	T	G	16: 58,746,485 (GRCm39)	I150L	probably benign	Het
Or5k17	G	T	16: 58,746,486 (GRCm39)	F149L	probably benign	Het
Or6d12	T	A	6: 116,493,315 (GRCm39)	N192K	probably benign	Het
Or6k2	T	C	1: 173,986,456 (GRCm39)	I39T	probably benign	Het
Or8b48	T	A	9: 38,493,373 (GRCm39)	S267T	probably benign	Het
Osm	A	G	11: 4,188,504 (GRCm39)	N44D	possibly damaging	Het
Otop2	T	C	11: 115,219,912 (GRCm39)	Y251H	probably damaging	Het
Pappa	T	C	4: 65,074,612 (GRCm39)	S389P	possibly damaging	Het
Polr1d	C	T	5: 147,038,068 (GRCm39)	A19V	probably damaging	Het
Ptchd4	G	A	17: 42,814,276 (GRCm39)	V726M	probably benign	Het
Pzp	T	A	6: 128,473,626 (GRCm39)	D731V	probably benign	Het
Rgl2	A	T	17: 34,155,002 (GRCm39)	I669F	probably damaging	Het
Rpl38	T	C	11: 114,563,114 (GRCm39)	*71R	probably null	Het
Rufy1	G	A	11: 50,289,301 (GRCm39)	R514W	probably damaging	Het
Ruvbl2	G	A	7: 45,083,741 (GRCm39)		probably benign	Het
Scn9a	T	G	2: 66,363,657 (GRCm39)	I874L	probably damaging	Het
Slc14a2	A	G	18: 78,238,951 (GRCm39)	S85P	probably benign	Het
Slc17a1	A	G	13: 24,062,794 (GRCm39)	I287V	probably benign	Het
Slc35f3	T	A	8: 127,115,928 (GRCm39)	I285N	probably damaging	Het
Slx4	A	G	16: 3,805,927 (GRCm39)	S542P	possibly damaging	Het
Sox30	A	T	11: 45,908,180 (GRCm39)	L782F	probably damaging	Het
Sspo	A	G	6: 48,432,806 (GRCm39)	N894S	probably benign	Het
Syne1	G	A	10: 5,152,013 (GRCm39)	Q5765*	probably null	Het
Taar7e	T	C	10: 23,913,972 (GRCm39)	I154T	probably benign	Het
Tars1	A	G	15: 11,397,265 (GRCm39)		probably null	Het
Thap1	CAGCATCTGCTCGGAGCA	CAGCA	8: 26,650,884 (GRCm39)		probably null	Het
Tmem198b	A	T	10: 128,639,057 (GRCm39)	C29S	probably damaging	Het
Tnr	A	C	1: 159,722,617 (GRCm39)	M1021L	probably benign	Het
Tom1l1	G	A	11: 90,548,644 (GRCm39)	P309L	probably damaging	Het
Traf4	A	G	11: 78,051,927 (GRCm39)	S186P	probably benign	Het
Trpm1	T	G	7: 63,890,319 (GRCm39)	V974G	possibly damaging	Het
Tsga10	T	A	1: 37,880,359 (GRCm39)		probably benign	Het
Tyw1	G	A	5: 130,298,065 (GRCm39)	R202Q	probably damaging	Het
Vmn2r93	A	T	17: 18,524,281 (GRCm39)	I92F	probably damaging	Het
Zfp457	A	T	13: 67,441,965 (GRCm39)	D203E	probably benign	Het
Zfp518b	G	A	5: 38,831,501 (GRCm39)	S168F	probably damaging	Het
Zfp7	TGCGGGAAAGGTTTCCACCTGAGCG	TGCG	15: 76,774,800 (GRCm39)		probably benign	Het
Zfp777	G	A	6: 48,002,521 (GRCm39)	T523M	probably benign	Het

Other mutations in Nbeal1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Nbeal1	APN	1	60,274,350 (GRCm39)	nonsense	probably null	0.00
IGL00334:Nbeal1	APN	1	60,321,042 (GRCm39)	missense	probably damaging	0.98
IGL00334:Nbeal1	APN	1	60,367,262 (GRCm39)	missense	probably damaging	1.00
IGL00514:Nbeal1	APN	1	60,256,384 (GRCm39)	missense	probably benign	0.31
IGL00596:Nbeal1	APN	1	60,220,900 (GRCm39)	missense	probably damaging	0.96
IGL00654:Nbeal1	APN	1	60,234,170 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL00757:Nbeal1	APN	1	60,234,302 (GRCm39)	missense	possibly damaging	0.82
IGL00771:Nbeal1	APN	1	60,274,512 (GRCm39)	missense	probably benign	0.11
IGL01315:Nbeal1	APN	1	60,320,500 (GRCm39)	missense	probably damaging	1.00
IGL01445:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01456:Nbeal1	APN	1	60,269,787 (GRCm39)	missense	probably damaging	1.00
IGL01458:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01535:Nbeal1	APN	1	60,256,414 (GRCm39)	missense	probably damaging	1.00
IGL01608:Nbeal1	APN	1	60,281,694 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL02006:Nbeal1	APN	1	60,311,418 (GRCm39)	critical splice donor site	probably null
IGL02105:Nbeal1	APN	1	60,292,660 (GRCm39)	missense	probably damaging	1.00
IGL02409:Nbeal1	APN	1	60,368,494 (GRCm39)	missense	probably benign	0.01
IGL02713:Nbeal1	APN	1	60,274,396 (GRCm39)	missense	possibly damaging	0.94
IGL02720:Nbeal1	APN	1	60,323,146 (GRCm39)	missense	probably damaging	0.98
IGL02887:Nbeal1	APN	1	60,326,603 (GRCm39)	splice site	probably benign
IGL02945:Nbeal1	APN	1	60,245,569 (GRCm39)	missense	probably damaging	1.00
IGL03023:Nbeal1	APN	1	60,292,572 (GRCm39)	missense	probably damaging	0.98
IGL03114:Nbeal1	APN	1	60,317,886 (GRCm39)	missense	probably damaging	1.00
IGL03231:Nbeal1	APN	1	60,275,618 (GRCm39)	missense	probably benign	0.44
IGL03241:Nbeal1	APN	1	60,274,027 (GRCm39)	missense	possibly damaging	0.46
IGL03241:Nbeal1	APN	1	60,274,028 (GRCm39)	missense	probably benign	0.44
IGL03382:Nbeal1	APN	1	60,300,745 (GRCm39)	critical splice donor site	probably null
IGL03412:Nbeal1	APN	1	60,281,726 (GRCm39)	nonsense	probably null
coach	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
Committee	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
Disgrace	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
Dravrah	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
Harvard	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
horrified	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
Lampoon	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
lawyer	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
magistrate	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
Maratimus	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
National	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
phainopepla	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R3875_Nbeal1_770	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
satirical	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
silky	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
stiggs	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
3-1:Nbeal1	UTSW	1	60,303,431 (GRCm39)	splice site	probably benign
P0007:Nbeal1	UTSW	1	60,358,847 (GRCm39)	missense	probably damaging	0.98
P0028:Nbeal1	UTSW	1	60,331,096 (GRCm39)	missense	probably damaging	1.00
R0041:Nbeal1	UTSW	1	60,321,030 (GRCm39)	missense	probably benign	0.05
R0051:Nbeal1	UTSW	1	60,349,422 (GRCm39)	missense	probably benign	0.19
R0052:Nbeal1	UTSW	1	60,267,771 (GRCm39)	splice site	probably benign
R0054:Nbeal1	UTSW	1	60,326,560 (GRCm39)	utr 3 prime	probably benign
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0094:Nbeal1	UTSW	1	60,344,468 (GRCm39)	missense	possibly damaging	0.62
R0310:Nbeal1	UTSW	1	60,344,529 (GRCm39)	splice site	probably benign
R0324:Nbeal1	UTSW	1	60,332,032 (GRCm39)	missense	probably damaging	1.00
R0329:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0330:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0417:Nbeal1	UTSW	1	60,286,893 (GRCm39)	missense	probably benign	0.00
R0421:Nbeal1	UTSW	1	60,307,598 (GRCm39)	missense	probably benign	0.08
R0617:Nbeal1	UTSW	1	60,320,991 (GRCm39)	nonsense	probably null
R1034:Nbeal1	UTSW	1	60,329,165 (GRCm39)	nonsense	probably null
R1082:Nbeal1	UTSW	1	60,351,385 (GRCm39)	missense	probably damaging	0.99
R1123:Nbeal1	UTSW	1	60,299,428 (GRCm39)	missense	probably benign
R1187:Nbeal1	UTSW	1	60,233,687 (GRCm39)	missense	probably damaging	1.00
R1484:Nbeal1	UTSW	1	60,240,098 (GRCm39)	missense	probably damaging	1.00
R1594:Nbeal1	UTSW	1	60,344,450 (GRCm39)	missense	possibly damaging	0.91
R1651:Nbeal1	UTSW	1	60,239,278 (GRCm39)	missense	probably damaging	1.00
R1678:Nbeal1	UTSW	1	60,299,493 (GRCm39)	missense	probably benign	0.00
R1806:Nbeal1	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
R1937:Nbeal1	UTSW	1	60,307,100 (GRCm39)	nonsense	probably null
R1952:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R1953:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R2038:Nbeal1	UTSW	1	60,245,503 (GRCm39)	missense	probably benign	0.00
R2044:Nbeal1	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R2050:Nbeal1	UTSW	1	60,332,123 (GRCm39)	splice site	probably null
R2055:Nbeal1	UTSW	1	60,350,216 (GRCm39)	missense	probably damaging	1.00
R2064:Nbeal1	UTSW	1	60,309,515 (GRCm39)	missense	possibly damaging	0.89
R2100:Nbeal1	UTSW	1	60,344,430 (GRCm39)	splice site	probably null
R2181:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R2192:Nbeal1	UTSW	1	60,321,054 (GRCm39)	missense	probably damaging	1.00
R2203:Nbeal1	UTSW	1	60,323,165 (GRCm39)	missense	probably benign	0.21
R2267:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2268:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2351:Nbeal1	UTSW	1	60,276,257 (GRCm39)	missense	possibly damaging	0.90
R2366:Nbeal1	UTSW	1	60,290,511 (GRCm39)	missense	probably damaging	0.97
R2393:Nbeal1	UTSW	1	60,290,529 (GRCm39)	missense	probably damaging	0.98
R3545:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3546:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3547:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3701:Nbeal1	UTSW	1	60,290,572 (GRCm39)	splice site	probably benign
R3747:Nbeal1	UTSW	1	60,234,182 (GRCm39)	missense	probably damaging	0.98
R3875:Nbeal1	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
R4119:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R4256:Nbeal1	UTSW	1	60,370,107 (GRCm39)	missense	probably benign	0.19
R4371:Nbeal1	UTSW	1	60,329,105 (GRCm39)	missense	possibly damaging	0.95
R4450:Nbeal1	UTSW	1	60,306,933 (GRCm39)	missense	probably damaging	0.97
R4558:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R4618:Nbeal1	UTSW	1	60,267,890 (GRCm39)	intron	probably benign
R4673:Nbeal1	UTSW	1	60,368,549 (GRCm39)	missense	probably damaging	1.00
R4719:Nbeal1	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
R4798:Nbeal1	UTSW	1	60,261,352 (GRCm39)	splice site	probably null
R4826:Nbeal1	UTSW	1	60,290,501 (GRCm39)	missense	possibly damaging	0.79
R4841:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4842:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4895:Nbeal1	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
R4929:Nbeal1	UTSW	1	60,277,813 (GRCm39)	missense	probably damaging	1.00
R5026:Nbeal1	UTSW	1	60,276,338 (GRCm39)	missense	probably damaging	1.00
R5243:Nbeal1	UTSW	1	60,309,487 (GRCm39)	missense	probably damaging	0.99
R5300:Nbeal1	UTSW	1	60,274,718 (GRCm39)	nonsense	probably null
R5345:Nbeal1	UTSW	1	60,367,369 (GRCm39)	critical splice donor site	probably null
R5502:Nbeal1	UTSW	1	60,350,158 (GRCm39)	missense	probably damaging	1.00
R5542:Nbeal1	UTSW	1	60,316,353 (GRCm39)	missense	probably benign	0.00
R5555:Nbeal1	UTSW	1	60,276,311 (GRCm39)	missense	possibly damaging	0.93
R5580:Nbeal1	UTSW	1	60,281,761 (GRCm39)	missense	probably benign	0.45
R5765:Nbeal1	UTSW	1	60,331,006 (GRCm39)	missense	probably damaging	1.00
R5802:Nbeal1	UTSW	1	60,311,380 (GRCm39)	missense	probably benign	0.01
R5907:Nbeal1	UTSW	1	60,267,950 (GRCm39)	intron	probably benign
R5918:Nbeal1	UTSW	1	60,307,051 (GRCm39)	missense	possibly damaging	0.90
R5923:Nbeal1	UTSW	1	60,287,554 (GRCm39)	missense	probably damaging	1.00
R6066:Nbeal1	UTSW	1	60,287,564 (GRCm39)	missense	probably benign	0.29
R6091:Nbeal1	UTSW	1	60,220,715 (GRCm39)	start gained	probably benign
R6113:Nbeal1	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
R6143:Nbeal1	UTSW	1	60,290,466 (GRCm39)	missense	possibly damaging	0.81
R6194:Nbeal1	UTSW	1	60,296,643 (GRCm39)	missense	possibly damaging	0.80
R6197:Nbeal1	UTSW	1	60,261,287 (GRCm39)	missense	probably damaging	0.99
R6228:Nbeal1	UTSW	1	60,335,083 (GRCm39)	missense	probably benign	0.00
R6229:Nbeal1	UTSW	1	60,287,524 (GRCm39)	missense	possibly damaging	0.88
R6309:Nbeal1	UTSW	1	60,277,878 (GRCm39)	missense	probably benign
R6457:Nbeal1	UTSW	1	60,292,633 (GRCm39)	missense	probably benign	0.31
R6489:Nbeal1	UTSW	1	60,370,101 (GRCm39)	missense	possibly damaging	0.89
R6845:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R7021:Nbeal1	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
R7033:Nbeal1	UTSW	1	60,350,106 (GRCm39)	missense	probably damaging	1.00
R7144:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7145:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7146:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7157:Nbeal1	UTSW	1	60,299,793 (GRCm39)	nonsense	probably null
R7157:Nbeal1	UTSW	1	60,276,317 (GRCm39)	missense	probably damaging	1.00
R7209:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7210:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7211:Nbeal1	UTSW	1	60,240,110 (GRCm39)	missense	probably damaging	1.00
R7212:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7213:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7214:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7283:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7285:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7287:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7296:Nbeal1	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
R7312:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7313:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7329:Nbeal1	UTSW	1	60,256,355 (GRCm39)	missense	probably benign	0.39
R7380:Nbeal1	UTSW	1	60,283,969 (GRCm39)	missense	probably damaging	1.00
R7414:Nbeal1	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
R7477:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R7507:Nbeal1	UTSW	1	60,274,626 (GRCm39)	missense	probably damaging	1.00
R7642:Nbeal1	UTSW	1	60,316,386 (GRCm39)	missense	probably benign	0.31
R7678:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7689:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7728:Nbeal1	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
R7757:Nbeal1	UTSW	1	60,296,609 (GRCm39)	missense	probably damaging	0.97
R7761:Nbeal1	UTSW	1	60,358,500 (GRCm39)	missense	probably benign	0.00
R7813:Nbeal1	UTSW	1	60,331,048 (GRCm39)	missense	probably damaging	1.00
R7829:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7891:Nbeal1	UTSW	1	60,299,591 (GRCm39)	missense	probably benign
R7902:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R8022:Nbeal1	UTSW	1	60,299,431 (GRCm39)	nonsense	probably null
R8053:Nbeal1	UTSW	1	60,318,954 (GRCm39)	missense	probably damaging	0.98
R8169:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8170:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8178:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8182:Nbeal1	UTSW	1	60,239,292 (GRCm39)	missense	probably benign	0.00
R8186:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8187:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8193:Nbeal1	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
R8209:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8226:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8549:Nbeal1	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
R8560:Nbeal1	UTSW	1	60,274,316 (GRCm39)	missense	probably benign	0.38
R8753:Nbeal1	UTSW	1	60,307,542 (GRCm39)	missense	probably damaging	1.00
R8769:Nbeal1	UTSW	1	60,274,370 (GRCm39)	missense	probably damaging	0.99
R8771:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R8952:Nbeal1	UTSW	1	60,299,459 (GRCm39)	missense	probably benign	0.01
R9014:Nbeal1	UTSW	1	60,329,118 (GRCm39)	missense	probably damaging	1.00
R9056:Nbeal1	UTSW	1	60,317,885 (GRCm39)	missense	probably damaging	1.00
R9091:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9138:Nbeal1	UTSW	1	60,286,904 (GRCm39)	nonsense	probably null
R9168:Nbeal1	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
R9200:Nbeal1	UTSW	1	60,320,425 (GRCm39)	missense	probably damaging	1.00
R9270:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9322:Nbeal1	UTSW	1	60,297,818 (GRCm39)	missense	possibly damaging	0.91
R9405:Nbeal1	UTSW	1	60,349,424 (GRCm39)	missense	probably damaging	1.00
R9554:Nbeal1	UTSW	1	60,290,287 (GRCm39)	nonsense	probably null
R9557:Nbeal1	UTSW	1	60,274,509 (GRCm39)	missense	probably benign
R9560:Nbeal1	UTSW	1	60,368,544 (GRCm39)	missense	probably damaging	1.00
R9641:Nbeal1	UTSW	1	60,350,247 (GRCm39)	missense	probably damaging	1.00
R9784:Nbeal1	UTSW	1	60,299,741 (GRCm39)	nonsense	probably null
X0022:Nbeal1	UTSW	1	60,316,391 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- CTGGCCTCGTAGAAAGGTAGTAG -3'
(R):5'- CCAAATACCATGAGAGCTCAGTAG -3'

Sequencing Primer
(F):5'- AAGGTAGTAGAATAGCTTCGGGGTTC -3'
(R):5'- GTAGTTGGACTGATCAACATG -3'

Posted On

2022-02-07