Incidental Mutation 'R9225:Ncoa6'
| ID |
699755 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ncoa6
|
| Ensembl Gene |
ENSMUSG00000038369 |
| Gene Name |
nuclear receptor coactivator 6 |
| Synonyms |
ASC-2, RAP250, NRC, AIB3, ASC2, PRIP |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9225 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
155232585-155315741 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 155249441 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 1288
(I1288F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045386
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043126]
[ENSMUST00000109670]
[ENSMUST00000123293]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000043126
AA Change: I1288F
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000045386
Gene: ENSMUSG00000038369
AA Change: I1288F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
47 |
190 |
3.3e-55 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109670
AA Change: I1288F
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000105295
Gene: ENSMUSG00000038369
AA Change: I1288F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
3.6e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000123293
AA Change: I1288F
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000118113
Gene: ENSMUSG00000038369
AA Change: I1288F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
2.4e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
564 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes for targeted null mutations exhibit retarded embryonic growth and defects of the placenta, heart, liver, and nervous system. Mutants die around midgestation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310003L06Rik |
G |
T |
5: 88,120,433 (GRCm39) |
V397L |
probably benign |
Het |
| Adam26b |
G |
T |
8: 43,973,453 (GRCm39) |
Y516* |
probably null |
Het |
| Afap1 |
A |
G |
5: 36,133,968 (GRCm39) |
K468E |
possibly damaging |
Het |
| Ank2 |
A |
G |
3: 126,736,111 (GRCm39) |
S3258P |
unknown |
Het |
| Ap1g1 |
A |
G |
8: 110,585,509 (GRCm39) |
K783E |
probably benign |
Het |
| Apbb1 |
A |
G |
7: 105,218,063 (GRCm39) |
S20P |
|
Het |
| Atg13 |
T |
C |
2: 91,519,128 (GRCm39) |
|
probably null |
Het |
| Atg16l2 |
A |
G |
7: 100,951,188 (GRCm39) |
V16A |
probably benign |
Het |
| Atp11a |
G |
A |
8: 12,867,005 (GRCm39) |
R144Q |
probably benign |
Het |
| Avpr1a |
A |
T |
10: 122,285,466 (GRCm39) |
T253S |
probably benign |
Het |
| B4galnt3 |
T |
C |
6: 120,195,928 (GRCm39) |
T300A |
probably damaging |
Het |
| Bag4 |
A |
G |
8: 26,261,270 (GRCm39) |
V157A |
probably benign |
Het |
| Brsk2 |
A |
G |
7: 141,547,039 (GRCm39) |
H494R |
probably damaging |
Het |
| Cacna2d2 |
G |
A |
9: 107,403,403 (GRCm39) |
G955S |
probably benign |
Het |
| Ccdc42 |
A |
T |
11: 68,479,061 (GRCm39) |
E83V |
probably damaging |
Het |
| Cep120 |
T |
C |
18: 53,839,896 (GRCm39) |
Q788R |
probably benign |
Het |
| Cnbd1 |
A |
G |
4: 18,907,010 (GRCm39) |
I188T |
probably benign |
Het |
| Col6a6 |
C |
T |
9: 105,659,437 (GRCm39) |
E503K |
possibly damaging |
Het |
| Cpt1c |
A |
T |
7: 44,610,213 (GRCm39) |
L661H |
probably damaging |
Het |
| Cyp2a22 |
T |
C |
7: 26,637,202 (GRCm39) |
D194G |
possibly damaging |
Het |
| Cyp2c70 |
C |
A |
19: 40,168,912 (GRCm39) |
R125L |
probably damaging |
Het |
| Cyp3a41a |
A |
T |
5: 145,650,414 (GRCm39) |
D76E |
probably benign |
Het |
| Cyp4f13 |
A |
T |
17: 33,144,319 (GRCm39) |
I458N |
probably damaging |
Het |
| Cyp4f13 |
T |
C |
17: 33,148,175 (GRCm39) |
Q350R |
probably damaging |
Het |
| Ddx60 |
G |
A |
8: 62,470,875 (GRCm39) |
V1456I |
probably benign |
Het |
| Dgkh |
T |
C |
14: 78,962,507 (GRCm39) |
H8R |
probably damaging |
Het |
| Diaph3 |
A |
G |
14: 87,244,760 (GRCm39) |
|
probably null |
Het |
| Dnah8 |
A |
C |
17: 30,854,647 (GRCm39) |
D103A |
probably benign |
Het |
| Dock4 |
G |
A |
12: 40,879,669 (GRCm39) |
R1551Q |
probably benign |
Het |
| Eps8 |
A |
T |
6: 137,507,561 (GRCm39) |
S56T |
probably benign |
Het |
| Fam171b |
T |
A |
2: 83,710,386 (GRCm39) |
L686Q |
probably damaging |
Het |
| Fndc3b |
A |
C |
3: 27,510,680 (GRCm39) |
L814* |
probably null |
Het |
| Gcnt2 |
T |
A |
13: 41,014,336 (GRCm39) |
L169Q |
probably damaging |
Het |
| Gm21103 |
T |
A |
14: 17,484,877 (GRCm39) |
I56F |
possibly damaging |
Het |
| Gpc1 |
A |
T |
1: 92,783,742 (GRCm39) |
K276N |
probably damaging |
Het |
| Hivep1 |
T |
A |
13: 42,337,184 (GRCm39) |
V2421D |
probably damaging |
Het |
| Hoxb1 |
T |
C |
11: 96,257,119 (GRCm39) |
L156P |
probably benign |
Het |
| Ifi208 |
A |
G |
1: 173,518,294 (GRCm39) |
D467G |
possibly damaging |
Het |
| Klhl22 |
A |
G |
16: 17,594,617 (GRCm39) |
M249V |
probably damaging |
Het |
| Kmt2b |
A |
G |
7: 30,286,172 (GRCm39) |
V240A |
unknown |
Het |
| Lacc1 |
A |
T |
14: 77,272,414 (GRCm39) |
Y127* |
probably null |
Het |
| Lgr4 |
C |
A |
2: 109,842,485 (GRCm39) |
H823Q |
probably benign |
Het |
| Llgl1 |
T |
C |
11: 60,600,889 (GRCm39) |
S662P |
probably damaging |
Het |
| Lrrc1 |
G |
A |
9: 77,359,955 (GRCm39) |
T279I |
probably benign |
Het |
| Lrrc8e |
T |
A |
8: 4,284,561 (GRCm39) |
V262E |
probably damaging |
Het |
| Magi1 |
G |
T |
6: 93,762,511 (GRCm39) |
P292T |
possibly damaging |
Het |
| Mccc1 |
T |
A |
3: 36,018,511 (GRCm39) |
I608F |
probably benign |
Het |
| Mroh8 |
T |
A |
2: 157,107,010 (GRCm39) |
I220L |
probably damaging |
Het |
| Mtcl3 |
A |
T |
10: 29,072,327 (GRCm39) |
K540* |
probably null |
Het |
| Mycn |
C |
A |
12: 12,987,609 (GRCm39) |
D263Y |
probably damaging |
Het |
| Myrip |
A |
G |
9: 120,293,850 (GRCm39) |
K782E |
probably damaging |
Het |
| Nebl |
A |
G |
2: 17,405,322 (GRCm39) |
I399T |
possibly damaging |
Het |
| Neurod1 |
A |
T |
2: 79,284,731 (GRCm39) |
H217Q |
probably benign |
Het |
| Nlrp5 |
T |
C |
7: 23,117,371 (GRCm39) |
V365A |
probably benign |
Het |
| Or1e1 |
C |
A |
11: 73,244,595 (GRCm39) |
N5K |
probably damaging |
Het |
| Or2ag12 |
A |
G |
7: 106,276,976 (GRCm39) |
V239A |
probably benign |
Het |
| Or5b100-ps1 |
G |
C |
19: 12,994,371 (GRCm39) |
*261Y |
probably null |
Het |
| Or5b100-ps1 |
A |
G |
19: 12,994,370 (GRCm39) |
*261W |
probably null |
Het |
| Otud7a |
A |
G |
7: 63,407,469 (GRCm39) |
T591A |
possibly damaging |
Het |
| Pbx3 |
T |
C |
2: 34,260,938 (GRCm39) |
|
probably benign |
Het |
| Pcdhb4 |
A |
T |
18: 37,441,695 (GRCm39) |
Q335L |
possibly damaging |
Het |
| Plxnc1 |
C |
A |
10: 94,629,061 (GRCm39) |
C1571F |
probably damaging |
Het |
| Pola2 |
G |
A |
19: 6,000,492 (GRCm39) |
P330S |
probably benign |
Het |
| Ppm1l |
A |
T |
3: 69,460,244 (GRCm39) |
N274Y |
probably benign |
Het |
| Ppp4r3b |
A |
G |
11: 29,155,648 (GRCm39) |
D538G |
possibly damaging |
Het |
| Ptx4 |
C |
T |
17: 25,341,696 (GRCm39) |
T57I |
probably benign |
Het |
| Rchy1 |
A |
T |
5: 92,105,396 (GRCm39) |
C108* |
probably null |
Het |
| Rif1 |
A |
G |
2: 52,001,862 (GRCm39) |
E130G |
probably benign |
Het |
| Rmdn1 |
A |
T |
4: 19,601,385 (GRCm39) |
Y219F |
probably damaging |
Het |
| Rnf144a |
A |
G |
12: 26,377,606 (GRCm39) |
C46R |
probably damaging |
Het |
| Rpl13a |
C |
A |
7: 44,775,627 (GRCm39) |
G146V |
probably damaging |
Het |
| Rpl13a |
C |
A |
7: 44,775,628 (GRCm39) |
G146W |
probably damaging |
Het |
| Rtn3 |
A |
T |
19: 7,434,854 (GRCm39) |
N379K |
probably damaging |
Het |
| Sdc1 |
G |
T |
12: 8,821,817 (GRCm39) |
R19L |
unknown |
Het |
| Shank1 |
A |
G |
7: 43,983,470 (GRCm39) |
I651V |
unknown |
Het |
| Slamf6 |
T |
C |
1: 171,764,270 (GRCm39) |
V221A |
probably benign |
Het |
| Sp9 |
C |
A |
2: 73,103,839 (GRCm39) |
S131* |
probably null |
Het |
| Spen |
T |
C |
4: 141,202,943 (GRCm39) |
T1895A |
possibly damaging |
Het |
| Taf6l |
CGCAGCCGCACCTG |
CG |
19: 8,751,688 (GRCm39) |
|
probably benign |
Het |
| Thada |
G |
T |
17: 84,749,172 (GRCm39) |
H600N |
possibly damaging |
Het |
| Trmt11 |
G |
T |
10: 30,423,753 (GRCm39) |
P384Q |
probably damaging |
Het |
| Tsnaxip1 |
T |
C |
8: 106,566,659 (GRCm39) |
L165P |
probably damaging |
Het |
| Ttc7 |
A |
G |
17: 87,637,502 (GRCm39) |
Y419C |
probably damaging |
Het |
| Ugt1a6a |
T |
C |
1: 88,066,560 (GRCm39) |
F122S |
probably benign |
Het |
| Vmn1r218 |
G |
A |
13: 23,320,824 (GRCm39) |
C57Y |
probably benign |
Het |
| Vmn2r14 |
T |
C |
5: 109,369,288 (GRCm39) |
N95S |
probably damaging |
Het |
| Vmn2r2 |
G |
T |
3: 64,034,021 (GRCm39) |
H500Q |
probably benign |
Het |
| Vmn2r70 |
T |
A |
7: 85,208,242 (GRCm39) |
Y745F |
probably damaging |
Het |
| Zfp189 |
C |
T |
4: 49,530,193 (GRCm39) |
S432F |
probably benign |
Het |
| Zscan2 |
C |
T |
7: 80,513,021 (GRCm39) |
A2V |
probably damaging |
Het |
|
| Other mutations in Ncoa6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Ncoa6
|
APN |
2 |
155,248,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00849:Ncoa6
|
APN |
2 |
155,263,608 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL00933:Ncoa6
|
APN |
2 |
155,257,317 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00981:Ncoa6
|
APN |
2 |
155,248,099 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01420:Ncoa6
|
APN |
2 |
155,249,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ncoa6
|
APN |
2 |
155,263,003 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL03049:Ncoa6
|
APN |
2 |
155,260,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03194:Ncoa6
|
APN |
2 |
155,257,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03269:Ncoa6
|
APN |
2 |
155,248,409 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03299:Ncoa6
|
APN |
2 |
155,249,207 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03306:Ncoa6
|
APN |
2 |
155,247,427 (GRCm39) |
missense |
probably benign |
0.30 |
|
alcoa
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
Aluminum
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
balboa
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
mauna_loa
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4466001:Ncoa6
|
UTSW |
2 |
155,247,577 (GRCm39) |
missense |
probably benign |
|
|
R0011:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0014:Ncoa6
|
UTSW |
2 |
155,279,963 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0079:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0080:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0081:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0164:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0166:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0172:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0173:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0245:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0284:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0285:Ncoa6
|
UTSW |
2 |
155,257,621 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0285:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0288:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0539:Ncoa6
|
UTSW |
2 |
155,257,617 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0652:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0781:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1053:Ncoa6
|
UTSW |
2 |
155,275,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1110:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1420:Ncoa6
|
UTSW |
2 |
155,263,073 (GRCm39) |
nonsense |
probably null |
|
|
R1521:Ncoa6
|
UTSW |
2 |
155,257,142 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1541:Ncoa6
|
UTSW |
2 |
155,257,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1677:Ncoa6
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
R1858:Ncoa6
|
UTSW |
2 |
155,263,559 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1954:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1955:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2040:Ncoa6
|
UTSW |
2 |
155,248,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2087:Ncoa6
|
UTSW |
2 |
155,248,079 (GRCm39) |
nonsense |
probably null |
|
|
R2159:Ncoa6
|
UTSW |
2 |
155,249,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2278:Ncoa6
|
UTSW |
2 |
155,249,570 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2696:Ncoa6
|
UTSW |
2 |
155,279,935 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2891:Ncoa6
|
UTSW |
2 |
155,279,881 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3618:Ncoa6
|
UTSW |
2 |
155,249,709 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3747:Ncoa6
|
UTSW |
2 |
155,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3778:Ncoa6
|
UTSW |
2 |
155,263,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Ncoa6
|
UTSW |
2 |
155,249,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3802:Ncoa6
|
UTSW |
2 |
155,247,484 (GRCm39) |
missense |
probably benign |
|
|
R3820:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3821:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3822:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3870:Ncoa6
|
UTSW |
2 |
155,257,477 (GRCm39) |
splice site |
probably null |
|
|
R4037:Ncoa6
|
UTSW |
2 |
155,249,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4488:Ncoa6
|
UTSW |
2 |
155,249,396 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4719:Ncoa6
|
UTSW |
2 |
155,233,081 (GRCm39) |
unclassified |
probably benign |
|
|
R4732:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Ncoa6
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4835:Ncoa6
|
UTSW |
2 |
155,249,053 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4883:Ncoa6
|
UTSW |
2 |
155,248,687 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4967:Ncoa6
|
UTSW |
2 |
155,263,252 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5021:Ncoa6
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5234:Ncoa6
|
UTSW |
2 |
155,279,933 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5356:Ncoa6
|
UTSW |
2 |
155,263,112 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5358:Ncoa6
|
UTSW |
2 |
155,248,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5375:Ncoa6
|
UTSW |
2 |
155,275,915 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5412:Ncoa6
|
UTSW |
2 |
155,249,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5579:Ncoa6
|
UTSW |
2 |
155,248,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5618:Ncoa6
|
UTSW |
2 |
155,279,817 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5641:Ncoa6
|
UTSW |
2 |
155,263,756 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5757:Ncoa6
|
UTSW |
2 |
155,253,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Ncoa6
|
UTSW |
2 |
155,250,061 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5778:Ncoa6
|
UTSW |
2 |
155,248,688 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5852:Ncoa6
|
UTSW |
2 |
155,247,419 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5940:Ncoa6
|
UTSW |
2 |
155,257,785 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6155:Ncoa6
|
UTSW |
2 |
155,249,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6374:Ncoa6
|
UTSW |
2 |
155,263,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6389:Ncoa6
|
UTSW |
2 |
155,237,736 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6669:Ncoa6
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7097:Ncoa6
|
UTSW |
2 |
155,279,983 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7385:Ncoa6
|
UTSW |
2 |
155,249,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7963:Ncoa6
|
UTSW |
2 |
155,247,916 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8356:Ncoa6
|
UTSW |
2 |
155,248,172 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8698:Ncoa6
|
UTSW |
2 |
155,257,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8859:Ncoa6
|
UTSW |
2 |
155,248,388 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8870:Ncoa6
|
UTSW |
2 |
155,263,078 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9041:Ncoa6
|
UTSW |
2 |
155,257,450 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9062:Ncoa6
|
UTSW |
2 |
155,263,348 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9088:Ncoa6
|
UTSW |
2 |
155,249,726 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9445:Ncoa6
|
UTSW |
2 |
155,250,063 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9497:Ncoa6
|
UTSW |
2 |
155,248,238 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9514:Ncoa6
|
UTSW |
2 |
155,248,133 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9656:Ncoa6
|
UTSW |
2 |
155,274,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9720:Ncoa6
|
UTSW |
2 |
155,250,304 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9732:Ncoa6
|
UTSW |
2 |
155,244,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF033:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF040:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF048:Ncoa6
|
UTSW |
2 |
155,263,632 (GRCm39) |
small deletion |
probably benign |
|
|
X0017:Ncoa6
|
UTSW |
2 |
155,248,460 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1176:Ncoa6
|
UTSW |
2 |
155,263,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,263,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,248,062 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGGTAGTTTTCCTACTGGACC -3'
(R):5'- TTTCCAAATGTGGCTGCTCC -3'
Sequencing Primer
(F):5'- TGGACCCAGGACTCGAC -3'
(R):5'- TGGCTGCTCCAACCCAGAC -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation