Mutagenetix > Incidental Mutation

Incidental Mutation 'R9258:Nav3'

702043

Institutional Source

Beutler Lab

Gene Symbol

Nav3

Ensembl Gene

ENSMUSG00000020181

Gene Name

neuron navigator 3

Synonyms

Pomfil1p, 9630020C08Rik, POMFIL1, steerin 3, 4732483H20Rik, unc53H3

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9258 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

109517120-110292065 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 109550243 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Valine at position 1829 (E1829V)

Ref Sequence

ENSEMBL: ENSMUSP00000032719 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032719]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000032719
AA Change: E1829V

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000032719
Gene: ENSMUSG00000020181
AA Change: E1829V

Domain	Start	End	E-Value	Type
CH	79	182	4.41e-12	SMART
low complexity region	184	194	N/A	INTRINSIC
low complexity region	318	329	N/A	INTRINSIC
low complexity region	353	363	N/A	INTRINSIC
low complexity region	427	439	N/A	INTRINSIC
low complexity region	522	536	N/A	INTRINSIC
low complexity region	713	724	N/A	INTRINSIC
low complexity region	807	818	N/A	INTRINSIC
low complexity region	873	896	N/A	INTRINSIC
low complexity region	904	916	N/A	INTRINSIC
low complexity region	1077	1095	N/A	INTRINSIC
low complexity region	1160	1173	N/A	INTRINSIC
low complexity region	1207	1229	N/A	INTRINSIC
low complexity region	1256	1266	N/A	INTRINSIC
low complexity region	1274	1285	N/A	INTRINSIC
low complexity region	1293	1312	N/A	INTRINSIC
low complexity region	1327	1341	N/A	INTRINSIC
low complexity region	1383	1397	N/A	INTRINSIC
low complexity region	1462	1474	N/A	INTRINSIC
low complexity region	1550	1563	N/A	INTRINSIC
coiled coil region	1565	1656	N/A	INTRINSIC
low complexity region	1675	1692	N/A	INTRINSIC
low complexity region	1722	1733	N/A	INTRINSIC
low complexity region	1756	1781	N/A	INTRINSIC
low complexity region	1782	1795	N/A	INTRINSIC
coiled coil region	1801	1842	N/A	INTRINSIC
low complexity region	1848	1871	N/A	INTRINSIC
AAA	2029	2184	4.94e-7	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 97 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb10	T	A	8: 124,709,347 (GRCm39)	Q69L	probably benign	Het
Abtb2	A	C	2: 103,546,410 (GRCm39)	Q930P	probably null	Het
Adam18	G	A	8: 25,158,574 (GRCm39)	T73I	probably benign	Het
Ankrd54	A	T	15: 78,946,996 (GRCm39)	M1K	probably null	Het
Anks1	T	C	17: 28,277,400 (GRCm39)	V1106A	probably damaging	Het
Aox1	A	T	1: 58,351,515 (GRCm39)	I701F	probably damaging	Het
Arfgef3	C	T	10: 18,465,387 (GRCm39)	R2152H	probably damaging	Het
Arnt2	C	T	7: 84,010,798 (GRCm39)	G37E	probably damaging	Het
Arpp21	G	A	9: 111,953,956 (GRCm39)	T581M	probably benign	Het
Arvcf	A	G	16: 18,216,957 (GRCm39)	N428S	probably damaging	Het
C2cd3	A	G	7: 100,098,026 (GRCm39)	E1471G		Het
Cadm1	A	G	9: 47,710,730 (GRCm39)	K211R	probably benign	Het
Cdh6	A	G	15: 13,064,462 (GRCm39)	S143P	probably damaging	Het
Cep152	G	A	2: 125,421,356 (GRCm39)	Q1125*	probably null	Het
Cfap54	A	C	10: 92,770,960 (GRCm39)	S2095A	unknown	Het
Col12a1	T	C	9: 79,613,645 (GRCm39)	T67A	probably benign	Het
Col6a3	T	C	1: 90,700,703 (GRCm39)	N3216S	unknown	Het
Cpeb2	T	A	5: 43,391,455 (GRCm39)	L217Q		Het
Ctbp2	A	T	7: 132,597,021 (GRCm39)	N119K	probably damaging	Het
Des	G	T	1: 75,340,289 (GRCm39)	V399L	probably benign	Het
Dnah2	G	T	11: 69,368,079 (GRCm39)	H1753Q	probably damaging	Het
Dnajc6	T	C	4: 101,475,813 (GRCm39)	V562A	probably benign	Het
Dusp13b	T	C	14: 21,791,155 (GRCm39)	D99G	probably benign	Het
Ehd3	A	G	17: 74,127,561 (GRCm39)	I165V	probably benign	Het
Eme2	C	T	17: 25,112,053 (GRCm39)	V241M	probably damaging	Het
Eml5	A	G	12: 98,810,376 (GRCm39)	L860P	possibly damaging	Het
Eogt	T	A	6: 97,089,043 (GRCm39)	K521M	possibly damaging	Het
Epb41l5	T	C	1: 119,506,701 (GRCm39)	T489A	probably benign	Het
Fmo5	G	T	3: 97,558,802 (GRCm39)	V421L	probably benign	Het
Gabpa	C	T	16: 84,653,403 (GRCm39)	P268S	probably benign	Het
Gas2l3	G	T	10: 89,262,315 (GRCm39)	H136N	probably benign	Het
Gm5592	C	T	7: 40,938,407 (GRCm39)	A563V	possibly damaging	Het
Gpn3	A	T	5: 122,519,508 (GRCm39)	D205V	probably benign	Het
H13	T	C	2: 152,522,999 (GRCm39)	L104S	probably damaging	Het
H2-Q4	T	A	17: 35,599,105 (GRCm39)	V125E	probably benign	Het
Ifih1	A	G	2: 62,442,242 (GRCm39)	F374S	probably damaging	Het
Ildr2	A	G	1: 166,131,158 (GRCm39)	D338G	probably damaging	Het
Kmt2b	A	T	7: 30,281,893 (GRCm39)	N1162K	probably null	Het
Lmntd1	T	C	6: 145,359,256 (GRCm39)	D298G	probably damaging	Het
Lrrc32	T	A	7: 98,148,345 (GRCm39)	V375E	probably benign	Het
Lrrc37a	A	C	11: 103,393,022 (GRCm39)	I801R	probably benign	Het
Matcap1	A	G	8: 106,008,775 (GRCm39)	V414A	probably damaging	Het
Mgam	A	G	6: 40,657,121 (GRCm39)	E935G	probably benign	Het
Mms22l	A	T	4: 24,588,238 (GRCm39)	T917S	probably damaging	Het
Myo3a	A	T	2: 22,467,545 (GRCm39)	E1204D	possibly damaging	Het
Nccrp1	C	T	7: 28,245,632 (GRCm39)	G150D	probably damaging	Het
Nlrp4b	G	T	7: 10,444,087 (GRCm39)	W12L	probably damaging	Het
Nmb	T	C	7: 80,554,001 (GRCm39)	T71A	possibly damaging	Het
Ogfod2	T	A	5: 124,250,505 (GRCm39)	H35Q	probably benign	Het
Ola1	A	T	2: 72,929,732 (GRCm39)	S290R	probably damaging	Het
Or1e30	T	G	11: 73,678,281 (GRCm39)	N172K	probably benign	Het
Or4k47	A	T	2: 111,452,329 (GRCm39)	I30N	possibly damaging	Het
Or51v15-ps1	T	G	7: 103,278,543 (GRCm39)	Y208S	unknown	Het
Or52e2	C	A	7: 102,804,409 (GRCm39)	E182*	probably null	Het
Or5p68	T	G	7: 107,945,886 (GRCm39)	T101P	probably benign	Het
Or9i14	A	T	19: 13,792,099 (GRCm39)	L285*	probably null	Het
Pcsk9	T	C	4: 106,316,047 (GRCm39)	D132G	possibly damaging	Het
Pkhd1	A	T	1: 20,444,174 (GRCm39)	V2296E	probably damaging	Het
Prl2c5	A	T	13: 13,365,297 (GRCm39)	I151L	probably damaging	Het
Prl3d3	A	T	13: 27,344,931 (GRCm39)	D101V	possibly damaging	Het
Prrt1	A	G	17: 34,850,120 (GRCm39)	Y178C	probably damaging	Het
Rasal1	A	T	5: 120,793,155 (GRCm39)	I87F	possibly damaging	Het
Rpgrip1l	A	T	8: 91,987,614 (GRCm39)	Y814*	probably null	Het
Rpl3l	T	G	17: 24,951,447 (GRCm39)		probably null	Het
Rrbp1	C	A	2: 143,853,161 (GRCm39)		probably benign	Het
Ryr3	A	G	2: 112,483,364 (GRCm39)	S4158P	probably damaging	Het
Scube2	G	T	7: 109,398,515 (GRCm39)	S951Y	probably damaging	Het
Sec14l1	T	C	11: 117,041,002 (GRCm39)	V396A	probably benign	Het
Sh3gl1	T	A	17: 56,325,911 (GRCm39)	K173*	probably null	Het
Shank3	A	T	15: 89,388,521 (GRCm39)	E371V	probably damaging	Het
Slc25a24	A	G	3: 109,066,751 (GRCm39)	T302A	probably damaging	Het
Slc25a41	A	T	17: 57,348,580 (GRCm39)	H4Q	probably benign	Het
Slc45a1	A	T	4: 150,723,071 (GRCm39)	V271D	possibly damaging	Het
Smad6	A	T	9: 63,927,573 (GRCm39)	L245Q	probably damaging	Het
Smad7	C	A	18: 75,527,317 (GRCm39)	Q388K	probably damaging	Het
Snx29	G	T	16: 11,532,799 (GRCm39)	D348Y	possibly damaging	Het
Son	A	T	16: 91,474,570 (GRCm39)	H2418L	unknown	Het
Sppl3	G	A	5: 115,233,922 (GRCm39)	V331M	probably damaging	Het
St13	T	G	15: 81,272,569 (GRCm39)	T92P	probably benign	Het
St3gal4	A	G	9: 34,963,643 (GRCm39)	W222R	probably damaging	Het
Stk32a	T	A	18: 43,444,999 (GRCm39)	N264K	probably benign	Het
Stoml3	T	A	3: 53,405,397 (GRCm39)	I26N	possibly damaging	Het
Taf7	T	C	18: 37,776,021 (GRCm39)	E182G	probably damaging	Het
Tas2r138	A	G	6: 40,590,129 (GRCm39)	V39A	probably damaging	Het
Tbc1d12	A	G	19: 38,889,823 (GRCm39)	S418G	possibly damaging	Het
Tbr1	T	A	2: 61,642,723 (GRCm39)	C663S	probably benign	Het
Tmc5	A	T	7: 118,222,501 (GRCm39)	Y67F	probably benign	Het
Tnfsf4	A	C	1: 161,244,814 (GRCm39)	I168L	probably benign	Het
Trav5-1	T	G	14: 52,860,347 (GRCm39)	S51A	probably benign	Het
Trmt10c	A	T	16: 55,854,646 (GRCm39)	C330S	possibly damaging	Het
Trpm1	T	C	7: 63,884,713 (GRCm39)	M798T	probably benign	Het
Unc13d	AATGCCTCCCATGCC	AATGCCTCCCATGCCTCCCATGCC	11: 115,958,998 (GRCm39)		probably benign	Het
Unc13d	CATGCC	CATGCCTCCGATGCC	11: 115,959,007 (GRCm39)		probably benign	Het
Vmn1r199	A	G	13: 22,566,822 (GRCm39)	T39A	possibly damaging	Het
Vmn1r74	T	A	7: 11,580,999 (GRCm39)	C100S	possibly damaging	Het
Vmn2r77	T	A	7: 86,452,302 (GRCm39)	I494K	possibly damaging	Het
Wdr17	G	A	8: 55,112,654 (GRCm39)	Q816*	probably null	Het

Other mutations in Nav3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00095:Nav3	APN	10	109,677,594 (GRCm39)	missense	probably damaging	0.99
IGL00425:Nav3	APN	10	109,539,368 (GRCm39)	missense	probably benign	0.13
IGL00465:Nav3	APN	10	109,688,607 (GRCm39)	missense	probably damaging	0.99
IGL00531:Nav3	APN	10	109,539,171 (GRCm39)	missense	probably null	0.99
IGL00575:Nav3	APN	10	109,600,626 (GRCm39)	missense	probably damaging	0.98
IGL00770:Nav3	APN	10	109,652,124 (GRCm39)	missense	probably damaging	1.00
IGL00774:Nav3	APN	10	109,652,124 (GRCm39)	missense	probably damaging	1.00
IGL00858:Nav3	APN	10	109,578,493 (GRCm39)	missense	probably damaging	0.98
IGL00935:Nav3	APN	10	109,541,527 (GRCm39)	missense	probably benign
IGL01638:Nav3	APN	10	109,688,724 (GRCm39)	missense	probably damaging	1.00
IGL01662:Nav3	APN	10	109,605,119 (GRCm39)	missense	possibly damaging	0.56
IGL01670:Nav3	APN	10	109,550,102 (GRCm39)	missense	possibly damaging	0.92
IGL01885:Nav3	APN	10	109,578,521 (GRCm39)	nonsense	probably null
IGL01979:Nav3	APN	10	109,540,790 (GRCm39)	missense	probably benign	0.01
IGL02121:Nav3	APN	10	109,594,897 (GRCm39)	missense	probably damaging	0.99
IGL02210:Nav3	APN	10	109,602,851 (GRCm39)	missense	probably benign
IGL02523:Nav3	APN	10	109,605,157 (GRCm39)	missense	probably damaging	1.00
IGL02573:Nav3	APN	10	109,702,835 (GRCm39)	missense	probably benign	0.23
IGL02633:Nav3	APN	10	109,527,997 (GRCm39)	missense	probably benign	0.09
IGL02810:Nav3	APN	10	109,652,135 (GRCm39)	missense	probably damaging	1.00
IGL02964:Nav3	APN	10	109,572,814 (GRCm39)	missense	probably damaging	0.99
IGL03015:Nav3	APN	10	109,554,158 (GRCm39)	missense	probably damaging	0.98
IGL03288:Nav3	APN	10	109,594,878 (GRCm39)	missense	probably damaging	1.00
IGL03310:Nav3	APN	10	109,660,433 (GRCm39)	critical splice donor site	probably null
PIT4377001:Nav3	UTSW	10	109,552,466 (GRCm39)	missense	probably damaging	0.99
R0010:Nav3	UTSW	10	109,659,087 (GRCm39)	splice site	probably benign
R0043:Nav3	UTSW	10	109,603,379 (GRCm39)	missense	possibly damaging	0.95
R0053:Nav3	UTSW	10	109,602,778 (GRCm39)	splice site	probably benign
R0053:Nav3	UTSW	10	109,602,778 (GRCm39)	splice site	probably benign
R0077:Nav3	UTSW	10	109,552,503 (GRCm39)	missense	possibly damaging	0.87
R0219:Nav3	UTSW	10	109,702,791 (GRCm39)	critical splice donor site	probably null
R0310:Nav3	UTSW	10	109,602,989 (GRCm39)	missense	possibly damaging	0.82
R0380:Nav3	UTSW	10	109,594,740 (GRCm39)	splice site	probably benign
R0403:Nav3	UTSW	10	109,602,964 (GRCm39)	missense	probably damaging	0.98
R0480:Nav3	UTSW	10	109,689,161 (GRCm39)	missense	probably damaging	1.00
R0626:Nav3	UTSW	10	109,659,325 (GRCm39)	missense	probably damaging	1.00
R0637:Nav3	UTSW	10	109,606,058 (GRCm39)	missense	probably benign	0.25
R0847:Nav3	UTSW	10	109,739,718 (GRCm39)	missense	possibly damaging	0.94
R0988:Nav3	UTSW	10	109,552,389 (GRCm39)	missense	probably damaging	1.00
R1272:Nav3	UTSW	10	109,572,860 (GRCm39)	missense	probably damaging	0.98
R1295:Nav3	UTSW	10	109,527,963 (GRCm39)	missense	probably damaging	1.00
R1405:Nav3	UTSW	10	109,606,194 (GRCm39)	splice site	probably benign
R1406:Nav3	UTSW	10	109,719,495 (GRCm39)	missense	possibly damaging	0.64
R1406:Nav3	UTSW	10	109,719,495 (GRCm39)	missense	possibly damaging	0.64
R1420:Nav3	UTSW	10	109,659,115 (GRCm39)	missense	probably benign	0.02
R1449:Nav3	UTSW	10	109,689,372 (GRCm39)	missense	probably benign	0.13
R1458:Nav3	UTSW	10	109,555,905 (GRCm39)	missense	probably damaging	1.00
R1469:Nav3	UTSW	10	109,596,369 (GRCm39)	missense	probably damaging	1.00
R1469:Nav3	UTSW	10	109,596,369 (GRCm39)	missense	probably damaging	1.00
R1472:Nav3	UTSW	10	109,563,802 (GRCm39)	missense	probably damaging	0.99
R1537:Nav3	UTSW	10	109,702,846 (GRCm39)	missense	probably damaging	1.00
R1539:Nav3	UTSW	10	109,603,031 (GRCm39)	missense	probably damaging	0.99
R1581:Nav3	UTSW	10	109,659,289 (GRCm39)	missense	probably damaging	1.00
R1586:Nav3	UTSW	10	109,689,115 (GRCm39)	missense	probably damaging	1.00
R1654:Nav3	UTSW	10	109,688,984 (GRCm39)	missense	possibly damaging	0.85
R1725:Nav3	UTSW	10	109,659,451 (GRCm39)	missense	probably damaging	1.00
R1742:Nav3	UTSW	10	109,605,074 (GRCm39)	missense	probably benign
R1793:Nav3	UTSW	10	109,539,233 (GRCm39)	missense	probably benign	0.00
R1830:Nav3	UTSW	10	109,659,184 (GRCm39)	missense	probably damaging	1.00
R1834:Nav3	UTSW	10	109,555,883 (GRCm39)	missense	probably damaging	0.99
R1881:Nav3	UTSW	10	109,688,420 (GRCm39)	missense	probably damaging	0.96
R1922:Nav3	UTSW	10	109,541,467 (GRCm39)	missense	probably benign	0.43
R1944:Nav3	UTSW	10	109,552,391 (GRCm39)	missense	probably damaging	0.99
R1981:Nav3	UTSW	10	109,554,951 (GRCm39)	splice site	probably benign
R1985:Nav3	UTSW	10	109,606,045 (GRCm39)	splice site	probably benign
R1996:Nav3	UTSW	10	109,689,262 (GRCm39)	missense	probably damaging	1.00
R2051:Nav3	UTSW	10	109,660,536 (GRCm39)	missense	probably damaging	0.99
R2062:Nav3	UTSW	10	109,555,882 (GRCm39)	missense	probably damaging	1.00
R2139:Nav3	UTSW	10	109,688,996 (GRCm39)	missense	probably benign	0.22
R2248:Nav3	UTSW	10	109,532,088 (GRCm39)	missense	probably damaging	1.00
R2420:Nav3	UTSW	10	109,699,674 (GRCm39)	missense	probably damaging	0.98
R2444:Nav3	UTSW	10	109,600,776 (GRCm39)	missense	probably benign	0.09
R3026:Nav3	UTSW	10	109,660,465 (GRCm39)	missense	probably damaging	0.99
R3052:Nav3	UTSW	10	109,739,613 (GRCm39)	missense	probably damaging	0.99
R3441:Nav3	UTSW	10	109,540,789 (GRCm39)	missense	probably benign	0.01
R3845:Nav3	UTSW	10	109,689,237 (GRCm39)	missense	possibly damaging	0.82
R3929:Nav3	UTSW	10	109,520,064 (GRCm39)	missense	probably damaging	1.00
R3932:Nav3	UTSW	10	109,529,896 (GRCm39)	missense	probably damaging	0.99
R4056:Nav3	UTSW	10	109,716,394 (GRCm39)	critical splice donor site	probably null
R4057:Nav3	UTSW	10	109,716,394 (GRCm39)	critical splice donor site	probably null
R4120:Nav3	UTSW	10	109,739,605 (GRCm39)	critical splice donor site	probably null
R4244:Nav3	UTSW	10	109,605,157 (GRCm39)	missense	probably damaging	1.00
R4361:Nav3	UTSW	10	109,688,847 (GRCm39)	missense	probably damaging	1.00
R4512:Nav3	UTSW	10	109,529,943 (GRCm39)	missense	possibly damaging	0.89
R4514:Nav3	UTSW	10	109,529,943 (GRCm39)	missense	possibly damaging	0.89
R4700:Nav3	UTSW	10	109,600,796 (GRCm39)	missense	probably benign	0.10
R4815:Nav3	UTSW	10	109,659,413 (GRCm39)	missense	probably benign
R4981:Nav3	UTSW	10	109,716,553 (GRCm39)	missense	probably benign
R5042:Nav3	UTSW	10	109,605,129 (GRCm39)	missense	probably benign	0.27
R5251:Nav3	UTSW	10	109,689,114 (GRCm39)	missense	probably damaging	0.99
R5252:Nav3	UTSW	10	109,550,152 (GRCm39)	small deletion	probably benign
R5273:Nav3	UTSW	10	109,528,899 (GRCm39)	critical splice donor site	probably null
R5288:Nav3	UTSW	10	109,688,966 (GRCm39)	missense	probably benign	0.10
R5407:Nav3	UTSW	10	109,702,796 (GRCm39)	missense	probably benign	0.28
R5533:Nav3	UTSW	10	109,719,539 (GRCm39)	missense	possibly damaging	0.61
R5561:Nav3	UTSW	10	109,552,413 (GRCm39)	missense	probably damaging	1.00
R5577:Nav3	UTSW	10	109,605,264 (GRCm39)	missense	probably damaging	1.00
R5656:Nav3	UTSW	10	109,600,494 (GRCm39)	missense	probably damaging	0.96
R5872:Nav3	UTSW	10	109,600,648 (GRCm39)	missense	probably damaging	1.00
R6023:Nav3	UTSW	10	109,659,376 (GRCm39)	missense	possibly damaging	0.95
R6061:Nav3	UTSW	10	109,702,845 (GRCm39)	nonsense	probably null
R6189:Nav3	UTSW	10	109,555,880 (GRCm39)	missense	probably damaging	0.98
R6214:Nav3	UTSW	10	109,688,426 (GRCm39)	missense	probably damaging	1.00
R6215:Nav3	UTSW	10	109,688,426 (GRCm39)	missense	probably damaging	1.00
R6264:Nav3	UTSW	10	109,524,694 (GRCm39)	missense	probably damaging	0.97
R6500:Nav3	UTSW	10	109,600,617 (GRCm39)	missense	probably damaging	1.00
R6524:Nav3	UTSW	10	109,555,891 (GRCm39)	missense	probably damaging	0.99
R6868:Nav3	UTSW	10	109,529,027 (GRCm39)	missense	possibly damaging	0.49
R7079:Nav3	UTSW	10	109,603,153 (GRCm39)	missense	probably benign	0.16
R7099:Nav3	UTSW	10	109,539,195 (GRCm39)	missense	probably benign	0.11
R7139:Nav3	UTSW	10	109,689,338 (GRCm39)	missense	probably benign	0.44
R7238:Nav3	UTSW	10	109,689,185 (GRCm39)	missense	possibly damaging	0.75
R7338:Nav3	UTSW	10	109,605,073 (GRCm39)	missense	probably benign	0.04
R7343:Nav3	UTSW	10	109,739,619 (GRCm39)	missense	probably damaging	0.98
R7383:Nav3	UTSW	10	109,552,532 (GRCm39)	missense	probably damaging	0.98
R7391:Nav3	UTSW	10	109,539,317 (GRCm39)	missense	probably benign	0.07
R7399:Nav3	UTSW	10	109,688,795 (GRCm39)	missense	possibly damaging	0.74
R7457:Nav3	UTSW	10	109,532,189 (GRCm39)	nonsense	probably null
R7462:Nav3	UTSW	10	109,659,439 (GRCm39)	missense	probably damaging	1.00
R7542:Nav3	UTSW	10	109,659,394 (GRCm39)	missense	possibly damaging	0.89
R7659:Nav3	UTSW	10	109,602,851 (GRCm39)	missense	probably benign	0.09
R7749:Nav3	UTSW	10	109,539,213 (GRCm39)	missense	probably damaging	0.99
R7794:Nav3	UTSW	10	109,524,717 (GRCm39)	missense	probably benign	0.08
R7876:Nav3	UTSW	10	109,689,359 (GRCm39)	missense	probably benign	0.26
R8048:Nav3	UTSW	10	109,600,779 (GRCm39)	missense	probably benign	0.13
R8104:Nav3	UTSW	10	109,594,828 (GRCm39)	missense	probably damaging	0.99
R8125:Nav3	UTSW	10	109,688,520 (GRCm39)	missense	probably damaging	0.99
R8275:Nav3	UTSW	10	109,527,984 (GRCm39)	missense	noncoding transcript
R8325:Nav3	UTSW	10	109,541,464 (GRCm39)	missense	probably benign	0.24
R8336:Nav3	UTSW	10	109,603,430 (GRCm39)	missense	probably damaging	0.99
R8523:Nav3	UTSW	10	109,659,138 (GRCm39)	missense	probably damaging	1.00
R8529:Nav3	UTSW	10	109,689,192 (GRCm39)	missense	probably benign	0.09
R8745:Nav3	UTSW	10	109,659,311 (GRCm39)	missense	probably benign	0.08
R8752:Nav3	UTSW	10	109,596,165 (GRCm39)	intron	probably benign
R8794:Nav3	UTSW	10	109,605,032 (GRCm39)	nonsense	probably null
R8816:Nav3	UTSW	10	109,699,721 (GRCm39)	missense	possibly damaging	0.69
R9029:Nav3	UTSW	10	109,699,613 (GRCm39)	missense	possibly damaging	0.68
R9117:Nav3	UTSW	10	109,520,100 (GRCm39)	missense	probably benign	0.41
R9126:Nav3	UTSW	10	109,541,524 (GRCm39)	missense	probably benign
R9347:Nav3	UTSW	10	109,738,955 (GRCm39)	missense	probably damaging	0.98
R9353:Nav3	UTSW	10	109,554,065 (GRCm39)	missense	probably damaging	0.99
R9366:Nav3	UTSW	10	109,659,364 (GRCm39)	missense	probably damaging	0.99
R9384:Nav3	UTSW	10	109,554,158 (GRCm39)	missense	probably damaging	0.98
R9428:Nav3	UTSW	10	109,605,176 (GRCm39)	missense	probably benign
R9454:Nav3	UTSW	10	109,835,864 (GRCm39)	missense	probably benign	0.01
R9516:Nav3	UTSW	10	109,520,015 (GRCm39)	missense	probably damaging	1.00
R9521:Nav3	UTSW	10	109,835,845 (GRCm39)	missense	possibly damaging	0.95
R9622:Nav3	UTSW	10	109,603,103 (GRCm39)	missense	probably benign
R9689:Nav3	UTSW	10	109,605,034 (GRCm39)	missense	probably damaging	1.00
R9796:Nav3	UTSW	10	109,527,969 (GRCm39)	missense	probably damaging	0.99
X0012:Nav3	UTSW	10	109,527,958 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ACTTGTGGGGATCTGAACAAATAC -3'
(R):5'- AACGGGTTCTCTTCTTTGGAATC -3'

Sequencing Primer
(F):5'- CACACAGGTATGCATGTAGGC -3'
(R):5'- GTTCTCTTCTTTGGAATCGTGTTTTC -3'

Posted On

2022-03-25