Incidental Mutation 'R9262:Jmjd1c'
| ID |
702326 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Jmjd1c
|
| Ensembl Gene |
ENSMUSG00000037876 |
| Gene Name |
jumonji domain containing 1C |
| Synonyms |
D630035I23Rik, TRIP8, 5430433L24Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.662)
|
| Stock # |
R9262 (G1)
|
| Quality Score |
216.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
66932189-67092105 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 67083793 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 2173
(I2173T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133700
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000051446]
[ENSMUST00000173689]
[ENSMUST00000174408]
|
| AlphaFold |
Q69ZK6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051446
AA Change: I2353T
PolyPhen 2
Score 0.390 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000056227
Gene: ENSMUSG00000037876
AA Change: I2353T
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
143 |
2236 |
N/A |
BLAST |
|
JmjC
|
2264 |
2488 |
3.29e-53 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173689
AA Change: I2173T
PolyPhen 2
Score 0.390 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000133700
Gene: ENSMUSG00000037876
AA Change: I2173T
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
1 |
2056 |
N/A |
BLAST |
|
JmjC
|
2084 |
2308 |
3.29e-53 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174408
AA Change: I2354T
PolyPhen 2
Score 0.390 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000134551
Gene: ENSMUSG00000037876
AA Change: I2354T
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
143 |
2237 |
N/A |
BLAST |
|
JmjC
|
2265 |
2489 |
3.29e-53 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
97% (73/75) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
PHENOTYPE: Mice homozygous for a null allele exhibit an age-dependent male infertility phenotype, characterized by early loss of undifferentiated spermatogonia, and a progressive reduction in testis size/weight and male germ cells, partly due to increased male germ cell apoptosis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933409G03Rik |
A |
T |
2: 68,443,375 (GRCm39) |
H192L |
unknown |
Het |
| Abca4 |
T |
A |
3: 121,964,639 (GRCm39) |
C2149S |
probably damaging |
Het |
| Abl2 |
G |
A |
1: 156,469,820 (GRCm39) |
G1028D |
possibly damaging |
Het |
| Adgre1 |
A |
G |
17: 57,754,941 (GRCm39) |
T680A |
probably damaging |
Het |
| Amn |
G |
A |
12: 111,237,585 (GRCm39) |
W10* |
probably null |
Het |
| Ankhd1 |
G |
T |
18: 36,765,799 (GRCm39) |
V140F |
|
Het |
| Asnsd1 |
A |
T |
1: 53,383,934 (GRCm39) |
N613K |
probably benign |
Het |
| Bbs2 |
A |
T |
8: 94,807,543 (GRCm39) |
I417N |
probably damaging |
Het |
| Cad |
T |
A |
5: 31,225,009 (GRCm39) |
W971R |
probably null |
Het |
| Cand2 |
A |
T |
6: 115,759,730 (GRCm39) |
I134F |
probably benign |
Het |
| Ccdc154 |
C |
A |
17: 25,389,160 (GRCm39) |
H453N |
probably damaging |
Het |
| Ccdc168 |
A |
G |
1: 44,096,269 (GRCm39) |
S1610P |
possibly damaging |
Het |
| Ccdc7a |
T |
A |
8: 129,486,277 (GRCm39) |
H1601L |
possibly damaging |
Het |
| Ccdc9 |
A |
C |
7: 16,012,400 (GRCm39) |
S261A |
probably benign |
Het |
| Cdkl3 |
T |
A |
11: 51,916,702 (GRCm39) |
S277T |
probably benign |
Het |
| Cipc |
T |
A |
12: 86,999,497 (GRCm39) |
Y8* |
probably null |
Het |
| Cramp1 |
A |
G |
17: 25,232,920 (GRCm39) |
S27P |
probably damaging |
Het |
| Csf1r |
A |
T |
18: 61,243,406 (GRCm39) |
M141L |
probably benign |
Het |
| Csf2rb2 |
G |
T |
15: 78,168,535 (GRCm39) |
F873L |
probably damaging |
Het |
| Dchs1 |
G |
A |
7: 105,404,833 (GRCm39) |
R2570W |
probably damaging |
Het |
| Dmxl1 |
A |
T |
18: 49,976,919 (GRCm39) |
N94Y |
probably benign |
Het |
| Dnajc10 |
A |
G |
2: 80,176,965 (GRCm39) |
K640R |
probably benign |
Het |
| Epha8 |
A |
C |
4: 136,658,995 (GRCm39) |
H886Q |
probably benign |
Het |
| Fcgbp |
G |
C |
7: 27,819,952 (GRCm39) |
D2560H |
probably damaging |
Het |
| Fry |
T |
G |
5: 150,305,109 (GRCm39) |
F605V |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,807,662 (GRCm39) |
N1327S |
probably benign |
Het |
| Gm12117 |
T |
C |
11: 33,226,001 (GRCm39) |
T112A |
probably benign |
Het |
| Gm3604 |
A |
T |
13: 62,517,697 (GRCm39) |
N220K |
probably damaging |
Het |
| Gm572 |
T |
C |
4: 148,735,652 (GRCm39) |
V27A |
probably benign |
Het |
| Gpr39 |
A |
G |
1: 125,800,524 (GRCm39) |
K425R |
probably benign |
Het |
| Heatr3 |
A |
G |
8: 88,883,097 (GRCm39) |
D349G |
probably benign |
Het |
| Hip1 |
A |
G |
5: 135,478,541 (GRCm39) |
S248P |
probably damaging |
Het |
| Itga11 |
A |
G |
9: 62,659,678 (GRCm39) |
|
probably benign |
Het |
| Itga3 |
C |
T |
11: 94,956,625 (GRCm39) |
V210I |
probably benign |
Het |
| Klf13 |
G |
A |
7: 63,574,456 (GRCm39) |
Q21* |
probably null |
Het |
| Kmt2a |
A |
T |
9: 44,731,222 (GRCm39) |
S3032T |
probably benign |
Het |
| Krt34 |
T |
C |
11: 99,930,851 (GRCm39) |
R184G |
probably benign |
Het |
| Krtap16-1 |
T |
C |
11: 99,876,994 (GRCm39) |
T137A |
probably benign |
Het |
| Ldc1 |
A |
G |
4: 130,114,153 (GRCm39) |
V88A |
possibly damaging |
Het |
| Mgam |
T |
C |
6: 40,723,422 (GRCm39) |
|
probably null |
Het |
| Mog |
T |
C |
17: 37,325,648 (GRCm39) |
T196A |
possibly damaging |
Het |
| Ms4a6d |
T |
C |
19: 11,579,216 (GRCm39) |
Y87C |
possibly damaging |
Het |
| Ndrg4 |
C |
T |
8: 96,435,812 (GRCm39) |
|
probably benign |
Het |
| Nsd1 |
T |
A |
13: 55,394,871 (GRCm39) |
M927K |
possibly damaging |
Het |
| Or11l3 |
T |
A |
11: 58,516,282 (GRCm39) |
M197L |
probably benign |
Het |
| Or4a73 |
G |
T |
2: 89,421,435 (GRCm39) |
T8K |
probably damaging |
Het |
| Ovgp1 |
T |
C |
3: 105,893,883 (GRCm39) |
|
probably benign |
Het |
| Pcdhac2 |
A |
G |
18: 37,279,095 (GRCm39) |
R692G |
possibly damaging |
Het |
| Pcsk4 |
T |
A |
10: 80,160,864 (GRCm39) |
S321C |
probably damaging |
Het |
| Pi4ka |
A |
G |
16: 17,120,859 (GRCm39) |
F1292L |
|
Het |
| Pigv |
G |
T |
4: 133,397,110 (GRCm39) |
P6Q |
possibly damaging |
Het |
| Pkhd1 |
A |
C |
1: 20,618,351 (GRCm39) |
S927A |
probably benign |
Het |
| Pnpla3 |
A |
T |
15: 84,055,363 (GRCm39) |
I90F |
probably benign |
Het |
| Pole |
C |
A |
5: 110,473,422 (GRCm39) |
L1739I |
probably damaging |
Het |
| Pole |
T |
A |
5: 110,473,423 (GRCm39) |
L1739H |
probably damaging |
Het |
| Rbm12 |
A |
T |
2: 155,939,317 (GRCm39) |
N318K |
possibly damaging |
Het |
| Rpl18a |
A |
T |
8: 71,348,179 (GRCm39) |
L168Q |
probably benign |
Het |
| Ryr2 |
T |
C |
13: 11,765,854 (GRCm39) |
N1294S |
probably damaging |
Het |
| Sema5b |
T |
C |
16: 35,453,223 (GRCm39) |
L98P |
possibly damaging |
Het |
| Slco1a8 |
G |
T |
6: 141,926,594 (GRCm39) |
F597L |
probably damaging |
Het |
| Smg7 |
A |
G |
1: 152,721,262 (GRCm39) |
V650A |
probably damaging |
Het |
| Spata31d1e |
T |
C |
13: 59,890,402 (GRCm39) |
M473V |
probably benign |
Het |
| Strada |
C |
T |
11: 106,075,444 (GRCm39) |
R13Q |
probably damaging |
Het |
| Sun1 |
T |
C |
5: 139,200,918 (GRCm39) |
S37P |
unknown |
Het |
| Syce1l |
T |
C |
8: 114,380,738 (GRCm39) |
|
probably null |
Het |
| Tdg |
T |
A |
10: 82,480,507 (GRCm39) |
F263L |
probably damaging |
Het |
| Tead3 |
G |
T |
17: 28,560,495 (GRCm39) |
S36R |
probably benign |
Het |
| Timm44 |
A |
G |
8: 4,310,621 (GRCm39) |
L377P |
probably damaging |
Het |
| Tk1 |
C |
T |
11: 117,716,581 (GRCm39) |
V9M |
probably benign |
Het |
| Trim36 |
A |
G |
18: 46,300,506 (GRCm39) |
Y722H |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,640,232 (GRCm39) |
M13792K |
possibly damaging |
Het |
| Unc80 |
A |
G |
1: 66,594,411 (GRCm39) |
|
probably benign |
Het |
| Usp46 |
G |
T |
5: 74,189,965 (GRCm39) |
A133E |
probably benign |
Het |
| Wnk2 |
T |
A |
13: 49,221,430 (GRCm39) |
R1240S |
probably benign |
Het |
| Zfp821 |
G |
A |
8: 110,450,982 (GRCm39) |
R325Q |
probably damaging |
Het |
|
| Other mutations in Jmjd1c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01062:Jmjd1c
|
APN |
10 |
67,062,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01604:Jmjd1c
|
APN |
10 |
67,085,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01753:Jmjd1c
|
APN |
10 |
67,067,794 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02081:Jmjd1c
|
APN |
10 |
67,055,305 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02128:Jmjd1c
|
APN |
10 |
67,079,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02134:Jmjd1c
|
APN |
10 |
67,056,171 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02215:Jmjd1c
|
APN |
10 |
67,056,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Jmjd1c
|
APN |
10 |
67,062,161 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02502:Jmjd1c
|
APN |
10 |
67,061,640 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02546:Jmjd1c
|
APN |
10 |
67,061,115 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02943:Jmjd1c
|
APN |
10 |
67,055,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03171:Jmjd1c
|
APN |
10 |
67,061,277 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL03261:Jmjd1c
|
APN |
10 |
67,067,849 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Accordion
|
UTSW |
10 |
67,069,193 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4378001:Jmjd1c
|
UTSW |
10 |
67,065,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0126:Jmjd1c
|
UTSW |
10 |
67,055,105 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0133:Jmjd1c
|
UTSW |
10 |
67,076,587 (GRCm39) |
missense |
probably benign |
0.22 |
|
R0201:Jmjd1c
|
UTSW |
10 |
67,054,888 (GRCm39) |
missense |
unknown |
|
|
R0396:Jmjd1c
|
UTSW |
10 |
67,055,302 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0401:Jmjd1c
|
UTSW |
10 |
67,056,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0452:Jmjd1c
|
UTSW |
10 |
67,091,261 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0488:Jmjd1c
|
UTSW |
10 |
67,076,506 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0504:Jmjd1c
|
UTSW |
10 |
67,061,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Jmjd1c
|
UTSW |
10 |
67,061,568 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0673:Jmjd1c
|
UTSW |
10 |
67,062,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Jmjd1c
|
UTSW |
10 |
67,054,725 (GRCm39) |
splice site |
probably null |
|
|
R0755:Jmjd1c
|
UTSW |
10 |
66,932,378 (GRCm39) |
intron |
probably benign |
|
|
R1142:Jmjd1c
|
UTSW |
10 |
67,061,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1196:Jmjd1c
|
UTSW |
10 |
67,075,015 (GRCm39) |
splice site |
probably benign |
|
|
R1413:Jmjd1c
|
UTSW |
10 |
67,085,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1619:Jmjd1c
|
UTSW |
10 |
67,055,654 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1676:Jmjd1c
|
UTSW |
10 |
67,060,588 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1751:Jmjd1c
|
UTSW |
10 |
67,061,469 (GRCm39) |
missense |
probably benign |
|
|
R1950:Jmjd1c
|
UTSW |
10 |
67,075,701 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1968:Jmjd1c
|
UTSW |
10 |
67,061,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Jmjd1c
|
UTSW |
10 |
66,993,777 (GRCm39) |
nonsense |
probably null |
|
|
R2061:Jmjd1c
|
UTSW |
10 |
67,054,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Jmjd1c
|
UTSW |
10 |
67,075,242 (GRCm39) |
splice site |
probably null |
|
|
R2203:Jmjd1c
|
UTSW |
10 |
67,075,242 (GRCm39) |
splice site |
probably null |
|
|
R2256:Jmjd1c
|
UTSW |
10 |
67,061,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2312:Jmjd1c
|
UTSW |
10 |
67,074,629 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2349:Jmjd1c
|
UTSW |
10 |
67,091,279 (GRCm39) |
missense |
probably benign |
|
|
R2392:Jmjd1c
|
UTSW |
10 |
67,065,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3015:Jmjd1c
|
UTSW |
10 |
66,993,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3110:Jmjd1c
|
UTSW |
10 |
67,075,863 (GRCm39) |
splice site |
probably benign |
|
|
R4043:Jmjd1c
|
UTSW |
10 |
67,055,245 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4097:Jmjd1c
|
UTSW |
10 |
67,054,787 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4118:Jmjd1c
|
UTSW |
10 |
67,055,532 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4193:Jmjd1c
|
UTSW |
10 |
66,932,460 (GRCm39) |
intron |
probably benign |
|
|
R4352:Jmjd1c
|
UTSW |
10 |
67,080,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4577:Jmjd1c
|
UTSW |
10 |
67,085,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4630:Jmjd1c
|
UTSW |
10 |
66,993,753 (GRCm39) |
nonsense |
probably null |
|
|
R4717:Jmjd1c
|
UTSW |
10 |
66,993,830 (GRCm39) |
nonsense |
probably null |
|
|
R4741:Jmjd1c
|
UTSW |
10 |
67,060,718 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4774:Jmjd1c
|
UTSW |
10 |
67,060,571 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R4836:Jmjd1c
|
UTSW |
10 |
67,069,225 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4914:Jmjd1c
|
UTSW |
10 |
67,054,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4939:Jmjd1c
|
UTSW |
10 |
67,081,916 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5211:Jmjd1c
|
UTSW |
10 |
67,067,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5215:Jmjd1c
|
UTSW |
10 |
67,076,480 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5514:Jmjd1c
|
UTSW |
10 |
67,053,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5530:Jmjd1c
|
UTSW |
10 |
67,085,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5624:Jmjd1c
|
UTSW |
10 |
67,069,193 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5640:Jmjd1c
|
UTSW |
10 |
67,061,857 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5654:Jmjd1c
|
UTSW |
10 |
67,065,785 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5742:Jmjd1c
|
UTSW |
10 |
67,056,112 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5764:Jmjd1c
|
UTSW |
10 |
67,062,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6118:Jmjd1c
|
UTSW |
10 |
67,075,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6163:Jmjd1c
|
UTSW |
10 |
67,083,827 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6256:Jmjd1c
|
UTSW |
10 |
67,056,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6266:Jmjd1c
|
UTSW |
10 |
67,085,439 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6358:Jmjd1c
|
UTSW |
10 |
67,061,718 (GRCm39) |
missense |
probably benign |
|
|
R6430:Jmjd1c
|
UTSW |
10 |
67,059,939 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6455:Jmjd1c
|
UTSW |
10 |
67,061,795 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6887:Jmjd1c
|
UTSW |
10 |
67,025,599 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6895:Jmjd1c
|
UTSW |
10 |
67,052,869 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7041:Jmjd1c
|
UTSW |
10 |
67,056,388 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7095:Jmjd1c
|
UTSW |
10 |
67,055,411 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7113:Jmjd1c
|
UTSW |
10 |
66,993,780 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7225:Jmjd1c
|
UTSW |
10 |
67,061,844 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7249:Jmjd1c
|
UTSW |
10 |
67,025,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7361:Jmjd1c
|
UTSW |
10 |
67,054,143 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7383:Jmjd1c
|
UTSW |
10 |
67,025,537 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7460:Jmjd1c
|
UTSW |
10 |
67,052,815 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7475:Jmjd1c
|
UTSW |
10 |
67,061,092 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7502:Jmjd1c
|
UTSW |
10 |
67,067,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7699:Jmjd1c
|
UTSW |
10 |
67,054,195 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7745:Jmjd1c
|
UTSW |
10 |
67,052,824 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7897:Jmjd1c
|
UTSW |
10 |
67,075,644 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7908:Jmjd1c
|
UTSW |
10 |
67,061,621 (GRCm39) |
missense |
probably benign |
|
|
R7911:Jmjd1c
|
UTSW |
10 |
67,067,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7967:Jmjd1c
|
UTSW |
10 |
67,085,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8058:Jmjd1c
|
UTSW |
10 |
67,090,274 (GRCm39) |
missense |
not run |
|
|
R8224:Jmjd1c
|
UTSW |
10 |
67,080,628 (GRCm39) |
missense |
noncoding transcript |
|
|
R8251:Jmjd1c
|
UTSW |
10 |
67,075,068 (GRCm39) |
missense |
noncoding transcript |
|
|
R8797:Jmjd1c
|
UTSW |
10 |
67,060,616 (GRCm39) |
missense |
probably benign |
|
|
R8833:Jmjd1c
|
UTSW |
10 |
67,054,162 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9354:Jmjd1c
|
UTSW |
10 |
67,059,875 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9373:Jmjd1c
|
UTSW |
10 |
66,932,495 (GRCm39) |
intron |
probably benign |
|
|
R9477:Jmjd1c
|
UTSW |
10 |
66,993,734 (GRCm39) |
nonsense |
probably null |
|
|
R9519:Jmjd1c
|
UTSW |
10 |
66,993,798 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9701:Jmjd1c
|
UTSW |
10 |
67,060,745 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9802:Jmjd1c
|
UTSW |
10 |
67,060,745 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
RF011:Jmjd1c
|
UTSW |
10 |
67,055,978 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1088:Jmjd1c
|
UTSW |
10 |
67,073,953 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Jmjd1c
|
UTSW |
10 |
67,073,953 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Jmjd1c
|
UTSW |
10 |
67,081,904 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Jmjd1c
|
UTSW |
10 |
67,073,953 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGGTCACATTCCAGACTTTGTTG -3'
(R):5'- TAGTCCACGCTCAAAGCAG -3'
Sequencing Primer
(F):5'- AATTCCACGGTAGTTTGTGCTAC -3'
(R):5'- TCCACGCTCAAAGCAGGAGTG -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation