Mutagenetix > Incidental Mutation

Incidental Mutation 'R9264:Dnah10'

702415

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9264 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

124725085-124834308 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 124736836 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Glycine at position 347 (R347G)

Ref Sequence

ENSEMBL: ENSMUSP00000062995 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000058440
AA Change: R347G

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: R347G

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000141137
AA Change: R347G

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: R347G

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (58/58)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca15	A	T	7: 120,401,833 (GRCm38)	I1531L	probably benign	Het
Adam28	T	C	14: 68,607,465 (GRCm38)	Y791C	probably benign	Het
Ankrd40	T	A	11: 94,338,361 (GRCm38)	I262N	probably damaging	Het
Catsperg2	A	T	7: 29,698,188 (GRCm38)	N1033K	possibly damaging	Het
Cdh10	A	T	15: 18,963,995 (GRCm38)	D81V	probably damaging	Het
Cep290	T	C	10: 100,498,016 (GRCm38)	V310A	possibly damaging	Het
Cep78	T	C	19: 15,974,466 (GRCm38)	Y325C	probably damaging	Het
Clstn3	T	A	6: 124,459,768 (GRCm38)	D197V	probably damaging	Het
Col11a1	T	C	3: 114,212,160 (GRCm38)	I1647T	unknown	Het
Col5a1	G	A	2: 27,964,111 (GRCm38)	R569K	unknown	Het
Cspg4b	G	A	13: 113,319,480 (GRCm38)	V687M		Het
Cyp4a10	T	C	4: 115,524,278 (GRCm38)	S180P	probably benign	Het
D630045J12Rik	T	C	6: 38,158,238 (GRCm38)	I1336V	probably benign	Het
Dchs2	G	A	3: 83,270,477 (GRCm38)	V946M	probably damaging	Het
Dnah11	T	A	12: 118,027,527 (GRCm38)	D2368V	probably damaging	Het
Ganab	T	C	19: 8,912,864 (GRCm38)	I719T	possibly damaging	Het
Gm10944	C	A	10: 10,681,839 (GRCm38)	A11D	unknown	Het
Gmcl1	T	C	6: 86,714,213 (GRCm38)	M267V	probably benign	Het
Inhbe	T	A	10: 127,350,558 (GRCm38)	D251V	probably damaging	Het
Kcnj1	G	A	9: 32,396,358 (GRCm38)	R26Q	probably benign	Het
Lama5	A	G	2: 180,196,478 (GRCm38)		probably benign	Het
Lin9	T	A	1: 180,667,347 (GRCm38)	D251E	probably damaging	Het
Magel2	T	A	7: 62,378,596 (GRCm38)	I416N	possibly damaging	Het
Mdga2	T	C	12: 66,513,283 (GRCm38)	N772S	probably damaging	Het
Ms4a20	T	A	19: 11,116,466 (GRCm38)	M1L	probably benign	Het
Msh3	G	T	13: 92,349,304 (GRCm38)	Q171K	probably benign	Het
Mslnl	T	G	17: 25,742,532 (GRCm38)		probably benign	Het
Mtpn	A	G	6: 35,512,241 (GRCm38)	L116P	possibly damaging	Het
Myh7	T	C	14: 54,975,997 (GRCm38)	T1351A	probably benign	Het
Nectin3	A	T	16: 46,454,635 (GRCm38)	I353N	probably damaging	Het
Nprl3	A	T	11: 32,233,948 (GRCm38)	N500K	probably benign	Het
Nup93	T	A	8: 94,292,720 (GRCm38)	I181N	probably benign	Het
Optc	T	C	1: 133,905,240 (GRCm38)	I41V	probably benign	Het
Or1b1	G	A	2: 37,104,789 (GRCm38)	T287I	probably damaging	Het
Or4p23	T	C	2: 88,746,432 (GRCm38)	H152R	probably damaging	Het
Pcdh7	C	A	5: 58,129,321 (GRCm38)	N1246K	probably benign	Het
Pcdhb3	T	A	18: 37,302,113 (GRCm38)	D377E	probably benign	Het
Pnpla6	C	T	8: 3,523,294 (GRCm38)	P386L	probably benign	Het
Polr3a	T	C	14: 24,470,831 (GRCm38)	T587A	probably benign	Het
Pramel1	T	G	4: 143,398,529 (GRCm38)	L341R	probably damaging	Het
Rhot2	A	T	17: 25,841,766 (GRCm38)	N210K	probably damaging	Het
Slc37a1	A	G	17: 31,300,485 (GRCm38)	I12V	probably benign	Het
Spmip7	T	A	11: 11,464,678 (GRCm38)	D141E		Het
Sstr3	G	T	15: 78,539,592 (GRCm38)	N318K	probably damaging	Het
Ssx2ip	T	C	3: 146,437,200 (GRCm38)	V511A	probably benign	Het
Stfa1	G	A	16: 36,280,568 (GRCm38)	V57I	unknown	Het
Syne1	T	G	10: 5,262,793 (GRCm38)	R3265S	probably damaging	Het
Tacc2	G	T	7: 130,626,803 (GRCm38)	K1739N	probably damaging	Het
Tas2r143	A	T	6: 42,400,739 (GRCm38)	M168L	probably benign	Het
Tm4sf1	A	T	3: 57,294,610 (GRCm38)		probably null	Het
Ttc16	A	G	2: 32,763,005 (GRCm38)	I604T	possibly damaging	Het
Ugt1a10	T	A	1: 88,055,671 (GRCm38)	W64R	possibly damaging	Het
Usp34	A	T	11: 23,489,064 (GRCm38)	H3561L		Het
Vasp	C	T	7: 19,259,451 (GRCm38)	V276I	unknown	Het
Vwa3a	A	G	7: 120,775,464 (GRCm38)	N333S	probably benign	Het
Wipf3	A	G	6: 54,483,881 (GRCm38)	N105D	probably benign	Het
Zfp760	T	C	17: 21,723,682 (GRCm38)	S613P	possibly damaging	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,828,603 (GRCm38)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,746,616 (GRCm38)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,794,341 (GRCm38)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,775,512 (GRCm38)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,777,212 (GRCm38)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,779,154 (GRCm38)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,783,946 (GRCm38)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,821,341 (GRCm38)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,732,489 (GRCm38)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,803,328 (GRCm38)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,787,465 (GRCm38)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,768,927 (GRCm38)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,755,786 (GRCm38)	missense	probably benign
IGL01767:Dnah10	APN	5	124,743,737 (GRCm38)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,764,944 (GRCm38)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,783,921 (GRCm38)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,789,812 (GRCm38)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,804,746 (GRCm38)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,819,366 (GRCm38)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,833,423 (GRCm38)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,773,067 (GRCm38)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,773,819 (GRCm38)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,793,852 (GRCm38)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,821,287 (GRCm38)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,787,331 (GRCm38)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,799,005 (GRCm38)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,773,745 (GRCm38)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,826,863 (GRCm38)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,730,086 (GRCm38)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,798,014 (GRCm38)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,801,822 (GRCm38)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,763,133 (GRCm38)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,730,162 (GRCm38)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,764,886 (GRCm38)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,748,457 (GRCm38)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,817,643 (GRCm38)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,817,697 (GRCm38)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,754,290 (GRCm38)	missense	probably benign	0.06
frosty	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,829,529 (GRCm38)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,730,100 (GRCm38)	missense	probably benign
P0019:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
P0037:Dnah10	UTSW	5	124,817,992 (GRCm38)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,775,524 (GRCm38)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,726,902 (GRCm38)	missense	probably benign
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,830,744 (GRCm38)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,763,076 (GRCm38)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,834,075 (GRCm38)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,796,369 (GRCm38)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,823,352 (GRCm38)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,755,735 (GRCm38)	missense	probably benign
R0480:Dnah10	UTSW	5	124,808,851 (GRCm38)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,812,723 (GRCm38)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,775,250 (GRCm38)	splice site	probably null
R0599:Dnah10	UTSW	5	124,800,953 (GRCm38)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,750,812 (GRCm38)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,829,577 (GRCm38)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,797,938 (GRCm38)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,760,014 (GRCm38)	splice site	probably null
R1248:Dnah10	UTSW	5	124,755,823 (GRCm38)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,753,326 (GRCm38)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,774,986 (GRCm38)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,762,221 (GRCm38)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,798,945 (GRCm38)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,743,686 (GRCm38)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1479:Dnah10	UTSW	5	124,777,889 (GRCm38)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,754,239 (GRCm38)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,760,952 (GRCm38)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,829,614 (GRCm38)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,765,562 (GRCm38)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,760,091 (GRCm38)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,773,190 (GRCm38)	splice site	probably null
R1828:Dnah10	UTSW	5	124,761,279 (GRCm38)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,804,689 (GRCm38)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,832,526 (GRCm38)	splice site	probably null
R1893:Dnah10	UTSW	5	124,754,317 (GRCm38)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,758,430 (GRCm38)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,800,984 (GRCm38)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,782,268 (GRCm38)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,775,203 (GRCm38)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,833,988 (GRCm38)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,829,587 (GRCm38)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,746,704 (GRCm38)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,796,341 (GRCm38)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,814,674 (GRCm38)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,774,981 (GRCm38)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,761,237 (GRCm38)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,731,466 (GRCm38)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,819,221 (GRCm38)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,742,000 (GRCm38)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,762,865 (GRCm38)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,775,478 (GRCm38)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,817,670 (GRCm38)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,819,412 (GRCm38)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,796,258 (GRCm38)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,747,630 (GRCm38)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,773,031 (GRCm38)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,777,926 (GRCm38)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,730,137 (GRCm38)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,732,330 (GRCm38)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,819,925 (GRCm38)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,762,869 (GRCm38)	splice site	probably null
R4651:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,775,517 (GRCm38)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,747,745 (GRCm38)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,819,344 (GRCm38)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,773,132 (GRCm38)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,817,748 (GRCm38)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,762,196 (GRCm38)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,832,513 (GRCm38)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,779,258 (GRCm38)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,798,960 (GRCm38)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,787,420 (GRCm38)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,785,156 (GRCm38)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,791,787 (GRCm38)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,773,566 (GRCm38)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,743,629 (GRCm38)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,830,493 (GRCm38)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,753,168 (GRCm38)	missense	probably benign
R5587:Dnah10	UTSW	5	124,793,913 (GRCm38)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,742,026 (GRCm38)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,821,386 (GRCm38)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,747,746 (GRCm38)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,823,373 (GRCm38)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,808,729 (GRCm38)	missense	probably benign
R6021:Dnah10	UTSW	5	124,736,984 (GRCm38)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,801,860 (GRCm38)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,819,210 (GRCm38)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,805,897 (GRCm38)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,753,174 (GRCm38)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,785,175 (GRCm38)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,770,599 (GRCm38)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,823,318 (GRCm38)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,743,679 (GRCm38)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,794,219 (GRCm38)	splice site	probably null
R6275:Dnah10	UTSW	5	124,785,184 (GRCm38)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,775,080 (GRCm38)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,829,646 (GRCm38)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,809,269 (GRCm38)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,762,782 (GRCm38)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,758,355 (GRCm38)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,830,033 (GRCm38)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,760,159 (GRCm38)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,805,805 (GRCm38)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,808,812 (GRCm38)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,777,826 (GRCm38)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,790,000 (GRCm38)	splice site	probably null
R6932:Dnah10	UTSW	5	124,821,450 (GRCm38)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,787,426 (GRCm38)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,816,142 (GRCm38)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,822,945 (GRCm38)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,822,942 (GRCm38)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,813,828 (GRCm38)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,832,598 (GRCm38)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,821,269 (GRCm38)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,747,739 (GRCm38)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,799,031 (GRCm38)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,746,544 (GRCm38)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,817,712 (GRCm38)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,777,234 (GRCm38)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,782,361 (GRCm38)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,726,885 (GRCm38)	missense	probably benign
R7999:Dnah10	UTSW	5	124,725,258 (GRCm38)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,800,885 (GRCm38)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,746,612 (GRCm38)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,828,511 (GRCm38)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,754,266 (GRCm38)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,800,882 (GRCm38)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,755,726 (GRCm38)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,828,460 (GRCm38)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,750,794 (GRCm38)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,782,346 (GRCm38)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,832,502 (GRCm38)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,773,542 (GRCm38)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,736,831 (GRCm38)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,816,100 (GRCm38)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,726,847 (GRCm38)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,814,621 (GRCm38)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,775,346 (GRCm38)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,765,550 (GRCm38)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,818,117 (GRCm38)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,789,764 (GRCm38)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,800,951 (GRCm38)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,813,942 (GRCm38)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,736,993 (GRCm38)	missense
R9001:Dnah10	UTSW	5	124,775,451 (GRCm38)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,743,719 (GRCm38)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,828,077 (GRCm38)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,762,173 (GRCm38)	missense
R9133:Dnah10	UTSW	5	124,782,359 (GRCm38)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,830,411 (GRCm38)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,794,373 (GRCm38)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,741,925 (GRCm38)	missense	possibly damaging	0.94
R9266:Dnah10	UTSW	5	124,768,926 (GRCm38)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,794,443 (GRCm38)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,746,613 (GRCm38)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,823,444 (GRCm38)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,830,043 (GRCm38)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,775,185 (GRCm38)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,818,077 (GRCm38)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,777,907 (GRCm38)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
U24488:Dnah10	UTSW	5	124,813,980 (GRCm38)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,765,697 (GRCm38)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,775,355 (GRCm38)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,741,955 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,817,988 (GRCm38)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,747,619 (GRCm38)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- GTGCTGTCTTGCATTCCCAGTAG -3'
(R):5'- TGAAGTGACGTTCCACAGTG -3'

Sequencing Primer
(F):5'- CAGTAGGGTCCTGAGGTCCATTC -3'
(R):5'- GGACAGGAAGCGCACATTGTC -3'

Posted On

2022-03-25